{"id":12177,"date":"2020-10-26T12:32:00","date_gmt":"2020-10-26T07:02:00","guid":{"rendered":"https:\/\/www.rootsanalysis.com\/blog\/?p=12177"},"modified":"2026-07-09T13:20:52","modified_gmt":"2026-07-09T07:50:52","slug":"growing-microbial-based-biologics-pipeline-boosts-the-microbial-contract-biomanufacturing-market","status":"publish","type":"post","link":"https:\/\/www.rootsanalysis.com\/blog\/growing-microbial-based-biologics-pipeline-boosts-the-microbial-contract-biomanufacturing-market\/","title":{"rendered":"Microbial Fermentation: Growing Microbial-Based Biologics Pipeline"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The recent years have portrayed the renaissance in the domain of microbial fermentation, as microbial <a href=\"https:\/\/en.wikipedia.org\/wiki\/Biopharmaceutical\">biopharma industry<\/a> has once again gained attention towards the production of biologics using microbial expression system. The modification and innovation in the microbial fermentation based expression systems for the production of various biologics have side-lined some of the earlier concerns associated with them, such as folding of the biologics, and has led to high-quality <a href=\"https:\/\/www.rootsanalysis.com\/reports\/biopharmaceutical-contract-manufacturing-market\/250.html\">biologics contract manufacturing<\/a> in a larger quantity. The upscaled trend in adoption of production of biologics using microbial fermentation has been due to the advancements in the <a href=\"https:\/\/www.rootsanalysis.com\/blog\/renascence-of-microbial-manufacturing\/\">microbial fermentation companies<\/a> offering novel technologies \/ platforms. Over time, microbial fermentation domain has significantly evolved and has led to production of various biologics, primarily proteins. However, an increasing bend can be observed towards the microbial contract biomanufacturing domain.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.rootsanalysis.com\/reports\/microbial-contract-biomanufacturing-market.html\">microbial fermentation CMO market<\/a> is one of the few businesses that has been relatively less impacted amidst the COVID-19 pandemic. Moreover, as the disease spreads, the demand for the effective preventive and treatment solutions for COVID-19, is growing at a rapid pace. In this context, it is worth mentioning that the need for a faster means to produce biopharmaceuticals and various other biologics have put the microbial fermentation sector under the spotlight. Moreover, in order to meet the growing demand for modalities targeting COVID-19 and other novel biologics, CMOs are actively engaged in making necessary investments to expand their existing capabilities and capacities. Further, in general, any strategy conceived \/ deployed in this crisis must be communicated in an effective manner, across both public and private stakeholders in the industry.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Companies Involved in Microbial Fermentation<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Currently, over 115 industry players are actively involved in the microbial fermentation industry. The microbial fermentation <a href=\"https:\/\/www.rootsanalysis.com\/reports\/microbial-contract-biomanufacturing-market.html\">CMO market<\/a> is presently highly fragmented, featuring the presence of small companies (28%), mid-sized players (27%), large firms (25%) and very large firms (20%). Examples of well-established players engaged in this domain (<em>companies having more than 10,000 employees<\/em>) include (<em>in alphabetical order<\/em>) AbbVie Contract Manufacturing, GE Healthcare, Lonza, Pierre Fabre and Sandoz.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"593\" height=\"319\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Companies-Involved-RootsAnalysis.webp\" alt=\"Microbial Contract Biomanufacturing Market - sample highlights for service providers operating as per Roots Analysis\" class=\"wp-image-19425\" style=\"object-fit:contain;width:800px;height:431px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Companies-Involved-RootsAnalysis.webp 593w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Companies-Involved-RootsAnalysis-300x161.webp 300w\" sizes=\"auto, (max-width: 593px) 100vw, 593px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Location of Microbial Contract Biomanufacturing Facilities<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Europe emerged as the manufacturing hub for biologics produced using microbial expression systems, representing 43% of the total facilities presently. This is followed by North America (31%), and Asia Pacific and Middle East (26%). Within Europe, the UK (17%) and Germany (15%) emerged as the most prominent hubs for biologics manufactured using microbial expression systems. Whereas, North America, the US has emerged as the key hub for biologics manufactured using microbial expression systems. Further, in Asia Pacific and Middle East, it was observed that most of the manufacturing facilities are located in China (33%) and India (28%).<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"621\" height=\"342\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Geographical-Distribution-by-Comapny-Size-Roots.webp\" alt=\"Microbial Contract Biomanufacturing Market is growing but major players are limited to Western countries as per the industry data collated by Roots Analysis\" class=\"wp-image-19426\" style=\"object-fit:contain;width:800px;height:441px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Geographical-Distribution-by-Comapny-Size-Roots.webp 621w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Geographical-Distribution-by-Comapny-Size-Roots-300x165.webp 300w\" sizes=\"auto, (max-width: 621px) 100vw, 621px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Recent Developments in the Microbial Fermentation Market<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Since 2016, partnership activity within the microbial contract biomanufacturing domain has increased with an annualized growth rate of 9.3%. Manufacturing agreements have captured a substantial share in the partnerships related to <a href=\"https:\/\/www.rootsanalysis.com\/reports\/microbial-contract-biomanufacturing-market.html\">microbial contract biomanufacturing<\/a>, during the period of 2016-2020.This was followed by process development agreements, which have captured a significant share of the partnerships inked in this domain. Further the domain has witnessed some consolidation during the period of 2016-2020 (<em>till May<\/em>). We were able to identify the key value drivers, such as geographical consolidation, geographical expansion, capability expansion, capacity expansion and access to new technology behind the various acquisitions reported during the given time period. Majority (64%) of the acquisitions in the microbial contract biomanufacturing industry were focused on geographical expansion, followed by capability (55%) and capacity expansions (55%). Further, most of the expansions (33%) initiated within this domain were for the establishment of a new facility, followed by initiatives carried out for expansion of existing facilities (28%).<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"621\" height=\"335\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Recent-Developments-in-the-Microbial-Contract-Biomanufacturing-Roots.webp\" alt=\"Microbial Contract Biomanufacturing Market distribution by expansion types or key value drivers triggering the acquisition as well as year when partnership was developed as per Roots Analysis\" class=\"wp-image-19427\" style=\"object-fit:contain;width:800px;height:432px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Recent-Developments-in-the-Microbial-Contract-Biomanufacturing-Roots.webp 621w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Recent-Developments-in-the-Microbial-Contract-Biomanufacturing-Roots-300x162.webp 300w\" sizes=\"auto, (max-width: 621px) 100vw, 621px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Likely Growth of the Microbial Contract Biomanufacturing Market<\/strong><strong><\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.rootsanalysis.com\/reports\/microbial-contract-biomanufacturing-market.html\">microbial fermentation CMO market<\/a> is anticipated to grow at an annualized rate of approximately 9%, as the drug developers are anticipated to continue to outsource their manufacturing services in mid to long term.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"603\" height=\"328\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Market-Forecast-upto-2030-RootsAnalysis.webp\" alt=\"Microbial Contract Biomanufacturing Market analysis done by Roots Analysis includes distribution by product type or biologic type or expression system\" class=\"wp-image-19428\" style=\"object-fit:contain;width:800px;height:439px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Market-Forecast-upto-2030-RootsAnalysis.webp 603w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Microbial-Contract-Manufacturing-Market-Forecast-upto-2030-RootsAnalysis-300x163.webp 300w\" sizes=\"auto, (max-width: 603px) 100vw, 603px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">In the long-term, the projected opportunity is anticipated to be well distributed across scale of operation, size of contract service providers and various regions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">For more details, you can also download the&nbsp;<a href=\"https:\/\/www.rootsanalysis.com\/reports\/microbial-contract-biomanufacturing-market\/request-sample.html\">SAMPLE REPORT<\/a>&nbsp;on microbial fermentation by Roots Analysis.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Check out our new Reports Here-<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.rootsanalysis.com\/reports.html\">Roots Analysis &#8211; Research Insights<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The recent years have portrayed the renaissance in the domain of microbial fermentation, as microbial biopharma industry has once again gained attention towards the production of biologics using microbial expression system. The modification and innovation in the microbial fermentation based expression systems for the production of various biologics have side-lined some of the earlier concerns [&hellip;]<\/p>\n","protected":false},"author":41,"featured_media":12189,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[491,124,413,490,462],"tags":[256,492,174],"class_list":["post-12177","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biomanufacturing","category-contract-manufacturing","category-manufacturing","category-microbial-biopharma-industry","category-microbial-manufacturing","tag-biologics","tag-biomanufacturing","tag-contract-manufacturing"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Growing Microbial-Based Biologics Pipeline: Microbial Fermentation<\/title>\n<meta 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