{"id":9794,"date":"2019-04-30T13:21:47","date_gmt":"2019-04-30T13:21:47","guid":{"rendered":"https:\/\/www.rootsanalysis.com\/blog\/?p=9794"},"modified":"2026-07-30T18:20:06","modified_gmt":"2026-07-30T12:50:06","slug":"novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils","status":"publish","type":"post","link":"https:\/\/www.rootsanalysis.com\/blog\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\/","title":{"rendered":"Cancer Biomarkers Market: Focus on TMB, MSI \/ MMR and TILs Testing"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignleft\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2019\/05\/IO-Biomarkers-90678023_s-150x150.jpg\" alt=\"\" class=\"wp-image-9795\"\/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Advances in biotechnology have enabled the development of several high throughput tools, which have led to the establishment of better biomarkers based on genome \/ exome profiles. Novel biomarkers, such as tumour mutation burden (TMB), microsatellite instability (MSI) \/ mismatch repair (MMR) deficiency, tumour infiltrating lymphocytes (TILs) and certain others, are presently being investigated across numerous clinical studies.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I have highlighted below some of the most <a href=\"https:\/\/www.rootsanalysis.com\/reports\/cancer-biomarkers-market\/253.html\">interesting insights<\/a> from our study.\u00a0You can also access additional details here.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Advances in biotechnology have enabled the identification of several novel biomarkers, which are presently being used for a variety of purposes, including diagnosis, drug development, clinical research and to facilitate therapy-related decisions<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Several novel biomarkers are presently under investigation for a variety of cancer indications; the initiatives of big pharmaceutical companies are indicative of the growing interest in this domain<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Presently, close to 50 companies are offering a variety of analytical testing solutions for the assessment of novel biomarkers; majority of these tests are intended to facilitate important therapy-related decisions.<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Multiple tests are currently available for specific diseases indications; next generation sequencing has emerged as a key driver, enabling high throughput results and faster turnaround times <\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Companies involved in this domain are putting in significant efforts to develop efficient tests and differentiate their offerings, from those of other stakeholders, to maintain a competitive edge<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Till date, close to 200 trials, evaluating the expression of novel biomarkers have been registered across different cancer indications, phases of development and geographical locations<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The growing research activity in this domain is also evident across published scientific literature; several biomarker-focused studies are evaluating different types of immunotherapies <\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The opportunity is likely to be driven by the applicability of these tests across multiple cancer indications; the market is anticipated to grow as more biomarker based drugs get approved in the coming decade<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The projected future opportunity is expected to be distributed across different application areas, types of analytical techniques used and various global regions<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">To learn more, please click here. For any queries \/ suggestions, please do not hesitate to contact us at <a href=\"mailto:sales@rootsanalysis.com\">sales@rootsanalysis.com<\/a>. Alternatively, you can place an Order by filling this <a href=\"https:\/\/rootsanalysis.com\/dashboard\/uploads\/documents\/Novel%20Immuno-Oncology%20Biomarker%20Testing%20Market,%202019-2030%20(Order%20Form).pdf\">Order Form<\/a>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n","protected":false},"excerpt":{"rendered":"<p>Advances in biotechnology have enabled the development of several high throughput tools, which have led to the establishment of better biomarkers based on genome \/ exome profiles. Novel biomarkers, such as tumour mutation burden (TMB), microsatellite instability (MSI) \/ mismatch repair (MMR) deficiency, tumour infiltrating lymphocytes (TILs) and certain others, are presently being investigated across [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":18927,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[311],"tags":[347],"class_list":["post-9794","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-cancer-biomarkers"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cancer Biomarkers Market: Focus on TMB, MSI and TILs Testing<\/title>\n<meta name=\"description\" content=\"Several novel biomarkers are presently under investigation for a variety of cancer indications; the initiatives of big pharmaceutical\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rootsanalysis.com\/blog\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer Biomarkers Market: Focus on TMB, MSI and TILs Testing\" \/>\n<meta property=\"og:description\" content=\"Several novel biomarkers are presently under investigation for a variety of cancer indications; the initiatives of big pharmaceutical\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.rootsanalysis.com\/blog\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\/\" \/>\n<meta property=\"og:site_name\" content=\"Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/RootsAnalysis\/\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-30T13:21:47+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-30T12:50:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2019\/04\/Roots-Analysis-FeaturedImage-IO-Biomarkers.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"150\" \/>\n\t<meta property=\"og:image:height\" content=\"150\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Arun Gupta\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@RootsAnalysis\" \/>\n<meta name=\"twitter:site\" content=\"@RootsAnalysis\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Arun Gupta\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/\"},\"author\":{\"name\":\"Arun Gupta\",\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/#\\\/schema\\\/person\\\/af9198bf467c6e126793d9da458a1f62\"},\"headline\":\"Cancer Biomarkers Market: Focus on TMB, MSI \\\/ MMR and TILs Testing\",\"datePublished\":\"2019-04-30T13:21:47+00:00\",\"dateModified\":\"2026-07-30T12:50:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/\"},\"wordCount\":365,\"publisher\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/wp-content\\\/uploads\\\/2019\\\/04\\\/Roots-Analysis-FeaturedImage-IO-Biomarkers.webp\",\"keywords\":[\"Cancer Biomarkers\"],\"articleSection\":[\"Cancer\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/\",\"url\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/\",\"name\":\"Cancer Biomarkers Market: Focus on TMB, MSI and TILs Testing\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/novel-immuno-oncology-biomarker-testing-focus-on-tmbs-msis-mmrs-and-tils\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.rootsanalysis.com\\\/blog\\\/wp-content\\\/uploads\\\/2019\\\/04\\\/Roots-Analysis-FeaturedImage-IO-Biomarkers.webp\",\"datePublished\":\"2019-04-30T13:21:47+00:00\",\"dateModified\":\"2026-07-30T12:50:06+00:00\",\"description\":\"Several novel biomarkers are presently under investigation for a variety of cancer indications; 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