{"id":9866,"date":"2019-05-28T13:14:31","date_gmt":"2019-05-28T13:14:31","guid":{"rendered":"https:\/\/www.rootsanalysis.com\/blog\/?p=9866"},"modified":"2026-07-30T18:59:54","modified_gmt":"2026-07-30T13:29:54","slug":"neoantigen-targeted-therapies-mapping-the-future-growth-potential","status":"publish","type":"post","link":"https:\/\/www.rootsanalysis.com\/blog\/neoantigen-targeted-therapies-mapping-the-future-growth-potential\/","title":{"rendered":"Neoantigen Targeted Therapies: Mapping the Future Growth Potential"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The World Health Organization has estimated the number of new cancer cases, reported across the globe, to rise by 70% over the next 20 years. Conventional treatment options, such as chemotherapy, surgery and radiation therapy, continue to demonstrate limited efficacy in late-stage cancers. Recent developments in genomic analysis and advances in bioinformatics have enabled the adoption of more personalized treatment approaches, such as neoantigen targeted therapies. Currently, several neoantigen-based therapies are being investigated in combination with various immune checkpoint inhibitors, such as atezolizumab, durvalumab, ipilimumab and nivolumab.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I have highlighted below some of the most interesting insights from our study. You can also access additional details&nbsp;<a href=\"https:\/\/www.rootsanalysis.com\/reports\/neoantigen-targeted-therapies-market-2019-2030\/257.html\">Neoantigen Targeted Therapy Market<\/a>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><b>Advances in bioinformatics and genomic data analysis have enabled the identification of cancer antigens that are generally overlooked during immune surveillance; these neoantigens have been shown to possess substantial therapeutic potential<\/b><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Presently, over 130 neoantigen targeted therapies are being evaluated for advanced cancer indications and are designed for delivery via different routes of administration<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"499\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Clinical-and-Preclical-Pipeline-Roots-1024x499.webp\" alt=\"As per Roots Analysis, over 45 products are in preclinical stage followed by over 60 in early stage pipeline and around 20 in late stage clinical pipeline.\" class=\"wp-image-17919\" style=\"object-fit:contain;width:800px;height:390px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Clinical-and-Preclical-Pipeline-Roots-1024x499.webp 1024w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Clinical-and-Preclical-Pipeline-Roots-300x146.webp 300w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Clinical-and-Preclical-Pipeline-Roots-768x374.webp 768w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Clinical-and-Preclical-Pipeline-Roots.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Several molecules are in early stages of clinical development; based on delivery strategies, variety of vaccines and immunotherapies have been established for targeting personalized and shared antigens<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Over the years, more than 6,000 patents related to neoantigens and affiliated therapies have been granted \/ filed; this is indicative of the heightened pace of research in this field<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"499\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Publication-Analysis-Roots-1024x499.webp\" alt=\"The rising interest of stakeholders can be be attributed from the increasing numbers of publications by industry and non-industry players.\" class=\"wp-image-17920\" style=\"object-fit:contain;width:800px;height:389px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Publication-Analysis-Roots-1024x499.webp 1024w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Publication-Analysis-Roots-300x146.webp 300w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Publication-Analysis-Roots-768x374.webp 768w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Publication-Analysis-Roots.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><strong>Both industry and academic players are contributing to the innovation, which is evident across published scientific literature focused on multiple targeted therapies for a myriad of cancer indications<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Several investors, having realized the untapped opportunity within this emerging segment of cancer immunotherapy, have invested over USD 7 billion across 150 instances in the period between 2014 and 2019<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"499\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Funding-and-investments-Roots-1024x499.webp\" alt=\"Various stakeholders are continuously investing in neoantigen targeted therapies. Additionally, majority of the funding were raised in seed funding round. \" class=\"wp-image-17921\" style=\"object-fit:contain;width:800px;height:390px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Funding-and-investments-Roots-1024x499.webp 1024w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Funding-and-investments-Roots-300x146.webp 300w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Funding-and-investments-Roots-768x374.webp 768w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Funding-and-investments-Roots.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The increasing traction in this field is also reflected in the partnership activity; deals inked in the recent past focused on a diverse range of therapies, involving both international and indigenous stakeholders<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"499\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Partnerships-and-Collaborations-Roots-1024x499.webp\" alt=\"Over 20% of the deals were signed by various industry and non-industry players focused on protein \/ peptide-based vaccine.\" class=\"wp-image-17923\" style=\"object-fit:contain;width:800px;height:390px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Partnerships-and-Collaborations-Roots-1024x499.webp 1024w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Partnerships-and-Collaborations-Roots-300x146.webp 300w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Partnerships-and-Collaborations-Roots-768x374.webp 768w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Partnerships-and-Collaborations-Roots.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>The market will receive the required impetus after approval of the first neoantigen targeted therapy; the future growth is likely to be driven by the successful clinical outcomes of the late-stage molecules<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>In fact, opinions from industry experts confirm the vast potential of this segment of cancer immunotherapy, capable of targeting personalized \/ off-the-shelf tumour antigens with multiple types of vaccines and therapies <\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"499\" src=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Market-Forecast-Roots-1024x499.webp\" alt=\"The market for neoantigen targeted therapies is likely to be fragmented across neoantigen and immunotherapy \" class=\"wp-image-17924\" style=\"object-fit:contain;width:800px;height:390px\" srcset=\"https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Market-Forecast-Roots-1024x499.webp 1024w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Market-Forecast-Roots-300x146.webp 300w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Market-Forecast-Roots-768x374.webp 768w, https:\/\/www.rootsanalysis.com\/blog\/wp-content\/uploads\/2023\/10\/Neoantigen-Targeted-Therapies-Market-Forecast-Roots.webp 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\">To learn more, please click here. For any queries \/ suggestions, please do not hesitate to contact us at <a href=\"mailto:sales@rootsanalysis.com\">sales@rootsanalysis.com<\/a>. Alternatively, you can place an Order by filling this <a href=\"https:\/\/rootsanalysis.com\/dashboard\/uploads\/documents\/Neoantigen%20Targeted%20Therapies%20Market,%202019-2030%20(Order%20Form).pdf\">Order Form<\/a>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n","protected":false},"excerpt":{"rendered":"<p>The World Health Organization has estimated the number of new cancer cases, reported across the globe, to rise by 70% over the next 20 years. Conventional treatment options, such as chemotherapy, surgery and radiation therapy, continue to demonstrate limited efficacy in late-stage cancers. Recent developments in genomic analysis and advances in bioinformatics have enabled the [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":18922,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[58],"tags":[348],"class_list":["post-9866","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oncology","tag-neoantigen"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neoantigen Targeted Therapies: Future of Growth Potential<\/title>\n<meta name=\"description\" content=\"Presently, over 130 neoantigen targeted therapies are being evaluated for advanced cancer indications and are designed for delivery\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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