Research Insights

Driven by numerous developmental breakthroughs and encouraging clinical trial results demonstrating the vast potential of adoptive cell therapies (ACT), including CAR-T cell therapies, TCR therapies, TILs and natural killer cell therapies, this therapeutic modality has garnered considerable attention from the players engaged in the pharmaceutical industry. In fact, in the past few years, close to 30 cell and gene therapies have been approved by the US FDA. In addition, over 1,200 cell therapies more

Since the outbreak of COVID-19 infection, there has been immense pressure on the biopharmaceutical industry to reduce production timelines and increase the manufacturing capacity, without compromising on the quality of the final product. Further, a surge in morbidity across the globe and enhanced interconnectivity of equipment and technologies has led to an increased burden on manufacturing operations. Other factors that influenced the market include higher competition, competitive pricing, infl more

Since the mid-twentieth century, computing devices have continually been explored for applications beyond mere calculations, to emerge as machines that possess intelligence. These targeted efforts have contributed to the introduction of artificial intelligence, the next-generation simulator that employs programmed machines possessing the ability to comprehend data and execute the instructed tasks. The progress of artificial intelligence can be attributed to machine learning, a field of study imp more

Digital health is a broad concept that encompasses telemedicine, teleconsultation, remote monitoring, connected devices, digital health platforms and health applications. The outbreak of COVID-19 pandemic has propelled the usage of digital technologies in order to receive healthcare, remotely. The revolutionary developments in digital health have transformed medicine and biomedical science as well as promoted early disease diagnosis and treatment. In addition, several FemTech startups are focuse more

Digital therapeutics are clinically validated solutions that are delivered as applications, software and online programs, demonstrating the capability to facilitate positive outcomes when employed in the management of clinical conditions. These therapeutics are designed to engage patients in personalized treatment or disease prevention programs, through mediating behavioral or psychological modifications. The primary benefits of digital therapeutics include reduction of treatment related costs, more

It is a well-known fact that almost 90% of the therapeutic interventions fail in clinical trials, resulting in significant economic losses to the pharmaceutical industry.  The lack of effective preclinical prediction of drug responses in humans is one of the various reasons for drug’s failure to get approved. Animal testing for preclinical evaluation of drugs sometimes fails to identify toxicity signs caused by a drug in humans. Moreover, these studies are quite expensive, time-consum more

Cancer is the one of the leading cause of deaths, globally, as per the World Health Organization (WHO). Annual statistics reported by the American Cancer Society (ACR) indicate that, in 2022, around 1.9 million individuals are likely to be diagnosed with various types of cancer in the US. During the same year, around 0.6 million cancer-related deaths are anticipated to be reported in the aforementioned region. In this context, it is important to highlight that, according to the International Age more

The drug discovery process, which involves the identification of a relevant biological target and a corresponding pharmacological lead, is deemed crucial to the clinical success of a drug candidate. However, considering the growing complexity of modern pharmacology, the discovery of viable therapeutic candidates is very demanding, both in terms of time and capital investment. In fact, as per estimates, a therapeutic drug takes around 10 to 15 years and an average investment of USD 1 to 2 billion more

The oral solid dosage (OSD) market is the largest segment in the pharmaceutical industry, anticipated to reach over USD 900 billion by 2027. However, one of key concerns associated with this industry is that the active pharmaceutical ingredients (APIs) used in orally administered dosage forms inherently possess an unpleasant taste / odor. The existence of such taste in drug formulations is unappealing and has been shown to have a negative impact on patient compliance, particularly among the pedi more

The discovery and development process of a novel therapeutic candidate is often tedious and fraught with several challenges.The key concern associated with the overall process is the high attrition rate, which is often attributed to the trial-and-error approach followed for the drug discovery process.In fact, only a small proportion of pharmacological leads are translated into viable product candidates for clinical studies.  In addition, experts believe that close to 90% of the product cand more

Over the past few years, there have been several advancements in the field of digital health market; this has led to an increase in the adoption of digital healthcare solutions. Specifically, the outbreak of COVID-19 pandemic prompted people all over the world to rely on digital medium to receive healthcare remotely. Females constitute 49.6% of the world’s total population and, in one of its reports, the US department of labor reported that females use digital health care solutions more th more

The global healthcare sector has been overtly reluctant to embrace technology. This may partially be due to the failure of early digitization efforts, which were fraught with challenges and turned out to be more of a liability rather than a path forward. In fact, according to a study, clinicians ended up spending more than twice as much time on administrative work (49%), such as updating electronic medical records, than on seeing patients (27%). The delivery of modern healthcare services is, the more

It is a well-known fact that clinical trials form an integral part of the overall drug development process, enabling innovators to assess safety and efficacy of their drug candidates / devices. These studies account for around 50% of the total time and capital invested in the development process. However, the conduct of trials is often fraught with several challenges, including scientific and operational complexity, concerns associated with recruitment and retention of suitable patients, issues more

Various studies have indicated that the genetic composition of two individuals is unlikely to be similar. This can be attributed to the fact that the genetic makeup of an individual is influenced by various factors, such as family history, as well as environmental and health conditions. Therefore, one treatment cannot be expected to be successful in every patient suffering from the same disorder. It is worth highlighting that the inability to report a health issue to a medical practitioner in it more

Telehealth refers to the remote delivery of healthcare services, such as medical consults, examination / interpretation of medical reports, critical health parameter monitoring, medical information sharing (between physicians and their patients) and patient education, using modern telecommunications solutions. In other words, it offers a convenient and cost-effective way for individuals with health problems to seek medical attention from the comfort of their respective homes. Currently, a wide v more

The ongoing technological advancements, rising popularity of social media, use of virtual platforms in the ongoing COVID-19 pandemic and digitalization of the various aspects in the modern world have led to the generation of colossal amount of digital data. In fact, the amount of digital data being produced has grown exponentially over the last few years and is likely to witness significant rise in the future as well. The reliable and secure storage and accessibility of such voluminous data requ more

Over the past few years, an increase in the global disease burden has been observed. In fact, the failure to report a health issue to a healthcare provider, in its early stages, is anticipated to cost several billion dollars in excess, each year. Further, some individuals are required to visit a radiologist frequently for proper diagnosis of their health condition. This creates an additional burden on radiologists, as in most of the cases the examination is done manually. It is worth mentioning more

In the last few years, there has been an evident rise in the global disease burden. More importantly, the inability to report a health issue to a medical practitioner in its initial stages is expected to cost over USD 90 billion in excess and more than USD 40 billion in productivity loss, each year. Moreover, a number of individuals that are required to frequent hospitals for monitoring of their health conditions, such visits cause additional financial burden. The aforementioned concerns can be more
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