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The number of biopharmaceuticals being developed and manufactured has increased significantly in recent years. This is evident from the fact that over 10 novel biologics have been approved annually by FDA over the last three years; this represents around 30% of the total novel drugs approved during this time period. Currently, more than 50% of the drugs in clinical pipeline comprise of biologics. It is worth highlighting that most of these products are not stable as aqueous formulations, making it difficult to preserve them for longer durations. In order to achieve longer and commercially viable shelf lives, lyophilization has emerged as the preferred choice for making dry biopharmaceutical formulations. The method proves to be beneficial for biologics with stability issues or when providing exact dosage is challenging (for instance, very small and highly concentrated doses). In addition, it is suitable for biologics that are sensitive to heat, oxygen and / or humidity.
The lyophilization process requires specialized equipment, expertise and care. Contract manufacturing organizations (CMOs) that provide such services have specialized facilities and dedicated lines for lyophilization operations. A number of biopharmaceutical companies are outsourcing their lyophilization operations to CMOs to leverage their expertise and capabilities. It is well-known that setting up in-house lyophilization capabilities and operations is an expensive and time-consuming process. In order to decrease the overall cost of the product and yield cost savings, we expect that drug developers will continue to outsource such operations to CMOs. Key drivers, both in the short-mid term and long term, not only include the increasing demand for biological therapies but also the expected entry of a number of biosimilars and the technological advancements that are steadily resulting in improved productivity for clients.
Scope of the Report
The ‘Lyophilization Services for Biopharmaceuticals, 2017-2027’ report provides an extensive study on the current market landscape of lyophilization services for biopharmaceuticals. The study presents an in-depth analysis of a diverse set of companies that provide such services across different regions worldwide. In fact, we identified close to 90 companies that are actively involved in providing lyophilization services for biopharmaceuticals. In addition to other elements, the report covers the following:
The study features a detailed analysis of the existing size and potential future growth opportunities (2017-2027) in the lyophilization services market for biopharmaceuticals. We have provided insights on the likely regional evolution of the market covering North America, Europe (UK, France, Italy, Spain, Germany and rest of Europe), Asia Pacific (Japan, China, India and South Korea) and rest of the world. In addition, we have provided the likely evolution and a market attractiveness analysis on the basis of the type of containment system (bulk containers, vials, syringes, ampoules and cartridges). In order to account for the uncertainties associated with some of the key parameters and to add robustness to our model, we have presented three different forecast scenarios, depicting conservative, base and optimistic tracks of the market’s evolution.
The research, analysis and insights presented in this report are backed by a deep understanding of key insights gathered from both secondary and primary research. Actual figures have been sourced and analyzed from publicly available data. For the purpose of the study, we invited over 80 stakeholders to participate in a survey to solicit their opinions on upcoming opportunities, challenges and likely future trends. The opinions and insights presented in this study were also influenced by discussions conducted with experts in this field. These included contributions from Steven Nail (Principal Scientist, Baxter BioPharma Solutions), Adam Viverette (Lyophilization Manager, Patheon), Patrick DePalma (Director, CMO Business Development, BioDefense Division, Emergent BioSolutions) and John Shaw (Head of Business Development and Marketing, Vibalogics).
Chapter 2 provides an executive summary of the insights captured in our research. This summary offers a high level view on the current state of the lyophilization services market for biopharmaceuticals and its likely evolution in the mid-long term.
Chapter 3 provides an introduction to the lyophilization approach. It includes a detailed discussion on the history / evolution of the lyophilization technology, the principle on which the process is based, the basic components of a lyophilizer, and highlights the advantages / disadvantages and applications of the lyophilization process.
Chapter 4 highlights the importance of lyophilization for biopharmaceuticals. It elaborates on the steps involved in the process of lyophilization, lyophilization cycle development and optimization, and the containment systems in which lyophilization services for biopharmaceuticals are carried out.
Chapter 5 includes a comprehensive market landscape of the companies that provide lyophilization services for biopharmaceuticals. It presents an analysis of the lyophilization service providers on the basis of their geographical location, types of biopharmaceuticals lyophilized (antibodies, ADCs, proteins, peptides, nucleic acids and vaccines), scale of operation (lab, clinical and commercial) and the containment systems (vials, bulk containers, syringes, cartridges and ampoules).
Chapter 6 provides detailed profiles of some of the lyophilization service providers for biopharmaceuticals based in North America. Each profile presents a brief overview of the company, its financial information, lyophilization capabilities and facilities, recent developments, and a comprehensive future outlook. The chapter also provides insights on the overall evolution of the North American lyophilization services market, specifically distributed on the basis of type of containment system.
Chapter 7 provides detailed profiles of some of the lyophilization service providers for biopharmaceuticals based in Europe. Each profile provides a brief overview of the company, its financial information, lyophilization capabilities and facilities, recent developments, and a comprehensive future outlook. The chapter also provides insights on the overall evolution of the European lyophilization services market, specifically distributed on the basis of type of containment system.
Chapter 8 provides brief profiles of some of the lyophilization service providers for biopharmaceuticals based in the Asia Pacific region. The chapter also provides insights on the overall evolution of the Asia Pacific lyophilization services market, specifically distributed on the basis of type of containment system.
Chapter 9 presents a comprehensive view on how the lyophilization services market for biopharmaceuticals is likely to evolve over the next ten years. We have segregated the financial opportunity on the basis of different regions (North America, Europe (UK, France, Italy, Spain, Germany and rest of Europe), Asia Pacific (Japan, China, India and South Korea) and rest of the world)and the type of containment system (bulk containers, vials, syringes, ampoules and cartridges). All our predictions are backed by robust analysis of data procured from both secondary and primary sources. The analysis also presents insightful 2 X 2 matrices based on Market Share and Market Attractiveness derived from the current and likely future state of the market. Due to uncertainties surrounding some of the assumptions within our forecast model, we have presented three different growth tracks outlined as the conservative, base and optimistic scenarios.
Chapter 10 provides a benchmark analysis of the companies that provide lyophilization services for biopharmaceuticals. The key parameters considered for this analysis include the scale of operation, number of biologics lyophilized and type of containment system used for the lyophilization of biologics. The analysis allows the companies to compare their existing capabilities within their peer group and identify opportunities to become more competitive in the industry.
Chapter 11 presents elaborate details on lyophilization cycle development and optimization services, highlighting the important parameters and techniques required for these processes and the list of players providing such services for biopharmaceuticals.
Chapter 12 features a case study on alternative methods to lyophilization such as spray drying, spray freeze drying, atmospheric spray freeze drying and vacuum foam drying. It specifically elaborates on spray drying, covering information such as step-wise approach, applications of spray drying for biopharmaceuticals, key players providing such services and an informed comparison with lyophilization.
Chapter 13 presents insights from the survey conducted for this study. We invited over 80 stakeholders involved in providing lyophilization services for biopharmaceuticals. The participants, who were primarily Directors / CXO level representatives of their respective companies, helped us develop a deeper understanding on the nature of their services and the associated commercial potential.
Chapter 14 summarizes the overall report. It presents a list of key takeaways and offers our independent opinion on the current market scenario and key trends that are likely to determine how the market is likely to evolve in the short and long term.
Chapter 15 is a collection of interview transcripts of our discussions with some of the key players in this industry. We have presented the details of our conversations with Steven Nail (Principal Scientist, Baxter BioPharma Solutions), Adam Viverette (Lyophilization Manager, Patheon), Patrick DePalma (Director, CMO Business Development, BioDefense Division, Emergent BioSolutions) and John Shaw (Head of Business Development and Marketing, Vibalogics).
Chapter 16 is an appendix, which provides tabulated data and numbers for all the figures in the report.
Chapter 17 is an appendix, which contains the list of companies and organizations that have been mentioned in the report.
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION TO LYOPHILIZATION
3.1. Chapter Overview
3.2. Lyophilization: Historical Background
3.3. Lyophilization: Underlying Principle
3.4. Lyophilization: Equipment
3.5. Lyophilization: Advantages and Disadvantages
3.6. Lyophilization: Applications
3.6.1. Pharmaceutical and Biotechnology Industry
3.6.2. Food Industry
3.6.3. Microbiology
3.6.4. Chemical Industry
3.6.5. Dairy Industry
3.6.6. Nutraceutical Industry
3.6.7. Floral Lyophilization
3.6.8. Other Applications
4. LYOPHILIZATION OF BIOPHARMACEUTICALS
4.1. Chapter Overview
4.2. Need for Lyophilization of Biopharmaceuticals
4.3. Lyophilization Process for Biopharmaceuticals
4.3.1. Formulation and Filling
4.3.2. Freezing
4.3.3. Primary Drying
4.3.4. Secondary Drying
4.4. Lyophilization Cycle Development and Optimization
4.5. Containment Systems Used for the Lyophilization of Biopharmaceuticals
5. COMPETITIVE LANDSCAPE
5.1. Chapter Overview
5.2. Lyophilization Service Providers for Biopharmaceuticals: Overall Landscape
5.3. Lyophilization Service Providers for Biopharmaceuticals: Analysis by Type of Biopharmaceuticals Lyophilized
5.4. Lyophilization Service Provides for Biopharmaceuticals: Analysis by Scale of Operation
5.5. Lyophilization Service Providers for Biopharmaceuticals: Analysis by Containment Systems
6. LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS: NORTH AMERICA
6.1. Chapter Overview
6.2. Anteco Pharma
6.2.1. Company Overview
6.2.2. Lyophilization Capabilities and Facilities
6.2.3. Recent Developments
6.2.4. Future Outlook
6.3. Axcellerate Pharma
6.3.1. Company Overview
6.3.2. Lyophilization Capabilities and Facilities
6.3.3. Recent Developments
6.3.4. Future Outlook
6.4. Berkshire Sterile Manufacturing
6.4.1. Company Overview
6.4.2. Lyophilization Capabilities and Facilities
6.4.3. Recent Developments
6.4.4. Future Outlook
6.5. Emergent BioSolutions
6.5.1. Company Overview
6.5.2. Financial Performance
6.5.3. Lyophilization Facilities and Capabilities
6.5.4. Recent Developments
6.5.5. Future Outlook
6.6. LSNE Contract Manufacturing
6.6.1. Company Overview
6.6.2. Lyophilization Capabilities and Facilities
6.6.3. Recent Developments
6.6.4. Future Outlook
6.7. Lyophilization Technology
6.7.1. Company Overview
6.7.2. Lyophilization Capabilities and Facilities
6.7.3. Recent Developments
6.7.4. Future Outlook
6.8. Quality BioResources
6.8.1. Company Overview
6.8.2. Lyophilization Capabilities and Facilities
6.8.3. Future Outlook
6.9. North America: Lyophilization Services Market for Biopharmaceuticals, 2017-2027 (USD Million)
6.9.1. North America Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System (USD Million)
7. LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS: EUROPE
7.1. Chapter Overview
7.2. Amatsigroup
7.2.1. Company Overview
7.2.2. Financial Performance
7.2.3. Lyophilization Capabilities and Facilities
7.2.4. Recent Developments
7.2.5. Future Outlook
7.3. Biopharma Technology
7.3.1. Company Overview
7.3.2. Lyophilization Capabilities and Facilities
7.3.3. Recent Developments
7.3.4. Future Outlook
7.4. Boehringer Ingelheim BioXcellence™
7.4.1. Company Overview
7.4.2. Financial Performance
7.4.3. Lyophilization Capabilities and Facilities
7.4.4. Recent Developments
7.4.5. Future Outlook
7.5. LYOCONTRACT
7.5.1. Company Overview
7.5.2. Lyophilization Capabilities and Facilities
7.5.3. Recent Developments
7.5.4. Future Outlook
7.6. Lyofal
7.6.1. Company Overview
7.6.2. Lyophilization Facilities and Capabilities
7.6.3. Recent Developments
7.6.4. Future Outlook
7.7. Vetter Pharma
7.7.1. Company Overview
7.7.2. Lyophilization Capabilities and Facilities
7.7.3. Recent Developments
7.7.4. Future Outlook
7.8. Europe: Lyophilization Services Market for Biopharmaceuticals, 2017-2027 (USD Million)
7.8.1. Europe Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System (USD Million)
8. LYOPHILIZATION SERVICE PROVIDERS FOR BIOPHARMACEUTICALS: ASIA PACIFIC
8.1. Chapter Overview
8.2. BioZed Engineering
8.3. Bovogen Biologics
8.4. CinnaGen
8.5. Mycenax Biotech
8.6. Piramal Pharma Solutions
8.7. Samsung Biologics
8.8. Siam Bioscience
8.9. WuXi AppTec
8.10. Asia Pacific: Lyophilization Services Market for Biopharmaceuticals, 2017-2027 (USD Million)
8.10.1. Asia Pacific Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System (USD Million)
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9. MARKET SIZING AND FORECAST
9.1. Chapter Overview
9.2. Forecast Methodology
9.3. Lyophilization Services Market for Biopharmaceuticals, 2017-2027 (USD Million)
9.4. Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Region (USD Million)
9.4.1. Lyophilization Services Market for Biopharmaceuticals: North America (USD Million)
9.4.2. Lyophilization Services Market for Biopharmaceuticals: Europe (USD Million)
9.4.3. Lyophilization Services Market for Biopharmaceuticals: Asia Pacific and Rest of the World (USD Million)
9.5. Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Type of Containment System (USD Million)
9.5.1. Lyophilization Services Market for Biopharmaceuticals: Market Attractiveness Analysis by Type of Containment System
10. BENCHMARK ANALYSIS
10.1. Chapter Overview
10.2. Benchmark Analysis: Methodology
10.3. Benchmark Analysis: Peer Groups
10.3.1. Benchmark Analysis: North America, Peer Group I
10.3.2. Benchmark Analysis: North America, Peer Group II
10.3.3. Benchmark Analysis: North America, Peer Group III
10.3.4. Benchmark Analysis: Europe, Peer Group IV
10.3.5. Benchmark Analysis: Europe, Peer Group V
10.3.6. Benchmark Analysis: Europe, Peer Group VI
10.3.7. Benchmark Analysis: Asia Pacific, Peer Group VII
10.3.8. Benchmark Analysis: Asia Pacific, Peer Group VIII
11. LYOPHILIZATION CYCLE DEVELOPMENT AND OPTIMIZATION
11.1. Chapter Overview
11.2. Lyophilization Cycle Development
11.3. Lyophilization Cycle Optimization
11.4. Lyophilization Cycle Development and Optimization: Service Providers
11.4.1. Lyophilization Cycle Development and Optimization Service Providers: Analysis by Type of Services
11.4.2. Lyophilization Cycle Development and Optimization Service Providers: Analysis by Company Size
11.4.3. Lyophilization Cycle Development and Optimization Service Providers: Analysis by Geography
11.5. Lyophilization Cycle Development and Optimization Service Providers: Company Snapshots
12. ALTERNATIVE APPROACHES TO LYOPHILIZATION
12.1. Chapter Overview
12.2. Spray Drying
12.2.1. Spray Drying: Process
12.2.2. Spray Drying: Applications
12.2.3. Spray Drying of Biopharmaceuticals
12.2.4. Spray Drying Service Providers for Biopharmaceuticals
12.2.5. Comparison: Lyophilization and Spray Drying
12.3. Spray Freeze Drying
12.4. Atmospheric Spray Freeze Drying
12.5. Vacuum Foam Drying
13. SURVEY ANALYSIS
13.1. Chapter Overview
13.2. Seniority Level of Respondents
13.3. Type of Biopharmaceuticals Lyophilized
13.4. Type of Containment System
13.5. Scale of Operation
13.6. Lyophilization Cycle Development and Optimization
13.7. Location of Lyophilization Facility
13.8. Likely Market Size
14. CONCLUSION
14.1. In Light of High Costs Associated with Establishing In-house Lyophilization Capabilities, Outsourcing has Emerged as a Convenient Alternative
14.2. Cycle Development and Optimization are Among the Key Lyophilization Processes; a Number of Players Specializing in These Services Have Entered the Market Expanding the Value Chain
14.3. Although Alternative Methods have Gained Attention in Recent Times, Lyophilization will Continue to Play a Pivotal Role
14.4. Fueled by the Growing Pipeline of Biopharmaceuticals, the Market is Likely to Witness Continuous Growth in the Coming Decade
15. INTERVIEW TRANSCRIPTS
15.1. Chapter Overview
15.2. Steven Nail, Principal Scientist, Baxter BioPharma Solutions
15.3. Adam Viverette, Lyophilization Manager, Patheon
15.4. Patrick DePalma, Director, CMO Business Development BioDefense Division, Emergent BioSolutions
15.5. John Shaw, Head of Business Development and Marketing, Vibalogics
APPENDIX 1: TABULATED DATA
APPENDIX 2: LIST OF COMPANIES AND ORGANIZATION
Figure 3.1 Lyophilization: Historical Timeline
Figure 3.2 Phase Diagram of Water
Figure 3.3 Sublimation of Ice Crystals
Figure 3.4 Components of a Lyophilizer
Figure 3.5 Applications of Lyophilization
Figure 4.1 Formulation and Filling of Biopharmaceuticals: Key Steps
Figure 4.2 Freezing of Biopharmaceuticals: Key Steps
Figure 5.1 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Geography
Figure 5.2 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Biopharmaceuticals Lyophilized
Figure 5.3 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Scale of Operation
Figure 5.4 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Containment System
Figure 6.1 Anteco Pharma: Service Portfolio
Figure 6.2 Axcellerate Pharma: Service Portfolio
Figure 6.3 Berkshire Sterile Manufacturing: Service Portfolio
Figure 6.4 Emergent BioSolutions: Service Portfolio
Figure 6.5 Emergent BioSolutions: Annual Revenues, 2011-2016 (USD Million)
Figure 6.6 Emergent BioSolutions: Revenues from Contract Manufacturing Operations, 2014-2016 (USD Million)
Figure 6.7 LSNE Contract Manufacturing: Service Portfolio
Figure 6.8 Lyophilization Technology: Service Portfolio
Figure 6.9 Quality BioResources: Service Portfolio
Figure 6.10 North America Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System, 2017-2027: Base Scenario (USD Million)
Figure 7.1 Amatsigroup: Service Portfolio
Figure 7.2 Biopharma Technology: Service Portfolio
Figure 7.3 Boehringer Ingelheim BioXcellence™: Service Portfolio
Figure 7.4 Boehringer Ingelheim: Annual Revenues, 2011–2016 (EUR Billion)
Figure 7.5 Boehringer Ingelheim: Revenues by Business Divisions, 2016 (EUR Billion)
Figure 7.6 Lyofal: Service Portfolio
Figure 7.7 Vetter Pharma: Service Portfolio
Figure 7.8 Europe Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System, 2017-2027: Base Scenario (USD Million)
Figure 8.1 BioZed Engineering: Service Portfolio
Figure 8.2 Bovogen Biologics: Service Portfolio
Figure 8.3 CinnaGen: Service Portfolio
Figure 8.4 Mycenax Biotech: Service Portfolio
Figure 8.5 Piramal Pharma Solutions: Service Portfolio
Figure 8.6 Samsung Biologics: Service Portfolio
Figure 8.7 Siam Bioscience: Service Portfolio
Figure 8.8 WuXi Biologics: Service Portfolio
Figure 8.9 Asia Pacific Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System, 2017-2027: Base Scenario (USD Million)
Figure 9.1 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Base Scenario (USD Million)
Figure 9.2 Lyophilization Services Market for Biopharmaceuticals, 2017, 2022 and 2027: Distribution by Region (%)
Figure 9.3 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: North America, Base Scenario (USD Million)
Figure 9.4 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Europe, Base Scenario (USD Million)
Figure 9.5 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Asia Pacific and Rest of the World, Base Scenario (USD Million)
Figure 9.6 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Type of Containment Systems, Base Scenario (USD Million)
Figure 9.7 Lyophilization Services Market for Biopharmaceuticals: Market Attractiveness Analysis by the Type of Containment System
Figure 10.1 Benchmark Analysis: Distribution by Company Size
Figure 10.2 Benchmark Analysis: North America, Peer Group I
Figure 10.3 Benchmark Analysis: North America, Peer Group II
Figure 10.4 Benchmark Analysis: North America, Peer Group III
Figure 10.5 Benchmark Analysis: Europe, Peer Group IV
Figure 10.6 Benchmark Analysis: Europe, Peer Group V
Figure 10.7 Benchmark Analysis: Europe, Peer Group VI
Figure 10.8 Benchmark Analysis: Asia Pacific, Peer Group VII
Figure 10.9 Benchmark Analysis: Asia Pacific, Peer Group VIII
Figure 11.1 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Type of Services
Figure 11.2 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Company Size
Figure 11.3 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Geography
Figure 12.1 Spray Drying: Process
Figure 13.1 Survey Analysis: Distribution by Geography
Figure 13.2 Survey Analysis: Seniority Levels of Respondents
Figure 13.3 Survey Analysis: Distribution by Type of Biopharmaceutical Lyophilized
Figure 13.4 Survey Analysis: Distribution by Type of Containment System
Figure 13.5 Survey Analysis: Distribution by Scale of Operation
Figure 13.6 Survey Analysis: Lyophilization Cycle Development and Optimization
Figure 13.7 Survey Analysis: Location of Lyophilization Facility
Figure 13.8 Survey Analysis: Likely Current Market Size
Figure 14.1 Lyophilization Services Market for Biopharmaceuticals: 2017, 2022 and 2027 (USD Million)
Table 3.1 Lyophilization: Advantages and Disadvantages
Table 5.1 List of Lyophilization Service Providers for Biopharmaceuticals
Table 5.2 Lyophilization Service Providers for Biopharmaceuticals: Type of Biopharmaceuticals Lyophilized
Table 5.3 Lyophilization Service Providers for Biopharmaceuticals: Scale of Operation
Table 5.4 Lyophilization Service Providers for Biopharmaceuticals: Type of Containment Systems Used for Lyophilization of Biopharmaceuticals
Table 6.1 Lyophilization Service Providers for Biopharmaceuticals: North America
Table 6.2 Emergent BioSolutions: Lyophilization Capacity
Table 7.1 Lyophilization Service Providers for Biopharmaceuticals: Europe
Table 8.1 Lyophilization Service Providers for Biopharmaceuticals: Asia Pacific
Table 10.1 Benchmark Analysis: Peer Groups
Table 11.1 Lyophilization Cycle Development and Optimization: Service Providers
Table 11.2 Axys-Network: Snapshot
Table 11.3 BSP Pharmaceuticals: Snapshot
Table 11.4 Clarity BioSolutions: Snapshot
Table 11.5 CMC Biologics: Snapshot
Table 11.6 CuriRx: Snapshot
Table 11.7 FUJIFILM Diosynth Biotechnologies: Snapshot
Table 11.8 GILYOS (GIeseler LYOphilization Solutions): Snapshot
Table 11.9 Markt Technologies: Snapshot
Table 11.10 PaizoBio: Snapshot
Table 11.11 Pierre Fabre: Snapshot
Table 11.12 SGS Group: Snapshot
Table 11.13 Singota Solutions: Snapshot
Table 11.14 Syngene: Snapshot
Table 11.15 Tofflon: Snapshot
Table 11.16 Wolfe Laboratories: Snapshot
Table 12.1 Spray Drying Service Providers for Biopharmaceuticals
Table 12.2 Comparison: Spray Drying and Lyophilization
Table 13.1 Survey Response: Overview of the Participating Companies
Table 13.2 Survey Response: Seniority Level of Respondents
Table 13.3 Survey Response: Type of Biopharmaceuticals Lyophilized
Table 13.4 Survey Response: Type of Containment System
Table 13.5 Survey Response: Scale of Operation
Table 13.6 Survey Response: Lyophilization Cycle Development and Optimization
Table 13.7 Survey Response: Location of Lyophilization Facility
Table 13.8 Survey Response: Likely Current Market Size
Table 16.1 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Type of Biopharmaceuticals Lyophilized
Table 16.2 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Scale of Operation
Table 16.3 Lyophilization Service Providers for Biopharmaceuticals: Distribution by Containment System
Table 16.4 Emergent BioSolutions: Annual Revenues, 2011-2016 (USD Million)
Table 16.5 Emergent BioSolutions: Revenues from Contract Manufacturing Operations, 2014-2016 (USD Million)
Table 16.6 North America Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Conservative Scenario, USD Million)
Table 16.7 North America Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Base Scenario, USD Million)
Table 16.8 North America Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Optimistic Scenario, USD Million)
Table 16.9 Boehringer Ingelheim: Annual Revenues, 2011–2016 (EUR Billion)
Table 16.10 Boehringer Ingelheim: Revenues by Business Divisions, 2016 (EUR Billion)
Table 16.11 Europe Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Conservative Scenario, USD Million)
Table 16.12 Europe Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Base Scenario, USD Million)
Table 16.13 Europe Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Optimistic Scenario, USD Million)
Table 16.14 Asia Pacific Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Conservative Scenario, USD Million)
Table 16.15 Asia Pacific Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Base Scenario, USD Million)
Table 16.16 Asia Pacific Lyophilization Services Market for Biopharmaceuticals: Distribution by Type of Containment System: 2017-2027 (Optimistic Scenario, USD Million)
Table 16.17 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Conservative Scenario (USD Million)
Table 16.18 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Base Scenario (USD Million)
Table 16.19 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Optimistic Scenario (USD Million)
Table 16.20 Lyophilization Services Market for Biopharmaceuticals, 2017, 2022 and 2027: Distribution by Region (%)
Table 16.21 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: North America, Conservative Scenario (USD Million)
Table 16.22 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: North America, Base Scenario (USD Million)
Table 16.23 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: North America, Optimistic Scenario (USD Million)
Table 16.24 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Europe, Conservative Scenario (USD Million)
Table 16.25 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Europe, Base Scenario (USD Million)
Table 16.26 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Europe, Optimistic Scenario (USD Million)
Table 16.27 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Asia Pacific and Rest of the World, Conservative Scenario (USD Million)
Table 16.28 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Asia Pacific and Rest of the World, Base Scenario (USD Million)
Table 16.29 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Asia Pacific and Rest of the World, Optimistic Scenario (USD Million)
Table 16.30 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Type of Containment Systems, Conservative Scenario (USD Million)
Table 16.31 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Type of Containment Systems, Base Scenario (USD Million)
Table 16.32 Lyophilization Services Market for Biopharmaceuticals, 2017-2027: Distribution by Type of Containment Systems, Optimistic Scenario (USD Million)
Table 16.33 Lyophilization Services Market for Biopharmaceuticals: Market Attractiveness Analysis by the Type of Containment System
Table 16.34 Benchmark Analysis: Distribution by Company Size
Table 16.35 Lyophilization Cycle Development and Optimization Service Providers: Distribution by Type of Services
Table 16.36 Survey Analysis: Distribution by Geography
Table 16.37 Survey Analysis: Seniority Levels of Respondents
Table 16.38 Survey Analysis: Distribution by Type of Biopharmaceuticals Lyophilized
Table 16.39 Survey Analysis: Distribution by Type of Containment System
Table 16.40 Survey Analysis: Distribution by Scale of Operation
Table 16.41 Survey Analysis: Lyophilization Cycle Development and Optimization Services
Table 16.42 Survey Analysis: Location of Lyophilization Facility
Table 16.43 Survey Analysis: Likely Current Market Size
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