Published: November 2025
Chromatography is a biophysical technique employed for the separation and identification of components within complex mixtures based on the differential partitioning of components between two phases. For instance, chromatography is used for purification of various types of proteins based on their characteristics, including total charge, size and shape, binding capacity with the stationary phase and hydrophobic groups present on the surface. Originally, chromatography was employed for separation of components based on their color, such as herbal pigments. Over time, it has undergone significant advancements and has become indispensable across diverse scientific disciplines. Its applications extend broadly across pharmaceutical development, biochemical research, environmental analysis, food safety and numerous industrial processes, underscoring its critical role in modern analytical science.
This versatile technique has become a valuable separation tool in biomedical and pharmaceutical analysis. Owing to this, the recent years have witnessed a gradual shift towards the advancement of chromatography techniques to make purification and separation processes more accurate and reliable. The ongoing innovations include miniaturization of chromatographic systems, facilitating the creation of microfluidic devices and portable instrumentation, to ultimately enhance efficiency, reduce sample consumption and improve operational convenience.
Column chromatography is expected to evolve with the introduction of novel stationary phases, incorporating advanced materials and surface modifications to enhance selectivity, resolution and analytical speed. Further, the integration of artificial intelligence (AI) and machine learning (ML) is expected to transform data analysis, method optimization and predictive modeling, thereby accelerating analytical workflows. In summary, the future trajectory of chromatography is characterized by continuous evolution, promising capabilities and expanded applicability across a diverse range of scientific and industrial domains.
Roots Analysis has conducted an exhaustive study on Chromatography Market featuring the current market landscape, market size and future opportunity for the chromatography instruments and consumables providers, over a span of next 10 years.
As the chromatography market continues to expand, with North America as a prominent hub of chromatography instruments and consumables providers, the rising adoption of chromatography techniques in drug development and other application areas will play a pivotal role in catalyzing the overall market growth.
1. Agilent Technologies
2. Bio-Rad Laboratories
3. JASCO
4. Millipore Sigma
5. Revvity
6. Sartorius
7. Shimadzu Scientific Instruments
8. Thermo Fisher Scientific
The figure below highlights the top eight ion exchange chromatography instrument manufacturers and consumable manufacturers:

Interested in exploring all 140+ ion chromatography instrument manufacturers and consumables manufacturers?
Let us dive deep into the details of the top eight ion chromatography instrument manufacturers and consumables manufacturers. It is essential to note that the selection of top players can differ substantially according to the defined criteria.
1. Agilent Technologies
Company Overview
Agilent Technologies is a US-based firm offering various instruments, consumables, software and services to its clients. The company provides a wide range of chromatography solutions across various applications for several industries, including pharmaceuticals, biotechnology, environmental, food and beverage industries. Additionally, the firm has a comprehensive portfolio of chromatography products, including gas chromatography (GC), liquid chromatography (LC), and HPLC systems. In addition to instruments, it also offers a range of chromatography consumables, such as columns, vials, syringes, and sample preparation products.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1999 |
| Number of Employees | 10,001+ |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In June 2025, Agilent Technologies participated in multiple conferences including:
Earlier, in May 2025, Agilent Technologies announced the inauguration of its first India Solution Center in Haryana, featuring dedicated zones for analytical and life science technologies.
To know more about the recent initiatives of Agilent Technologies and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
2. Bio-Rad Laboratories
Company Overview
Bio-Rad Laboratories is a US-based healthcare company engaged in the development of innovative products, serving life science researchers (in accelerating the discovery process) and medical diagnostic labs (in obtaining faster and improved results). The company claims to be among the top five life science companies in the world, offering a wide range of products, including instruments, software, consumables, and reagents. Further, Bio-Rad also provides various chromatography systems, resins, columns, and accessories for several applications, including protein purification, protein analysis, and biomolecule separation.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1952 |
| Number of Employees | 10,001+ |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In June 2025, Bio-Rad Laboratories participated in the Jefferies Global Healthcare Conference, held in New York, US.
In January 2025, the company launched Nuvia wPrime 2A Media, a scalable weak anion exchange and hydrophobic interaction (AEX-HIC) mixed-mode chromatography resin for small and large scale biomolecule purification.
To know more about the recent initiatives of Bio-Rad Laboratories and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
3. Jasco
Company Overview
JASCO is dedicated to advancing molecular spectroscopy and chromatography technologies for global life science, pharmaceutical, biotechnology, academic, and industrial researchers. The company is recognized for developing innovative solutions that enable precise analysis and separation, supporting applications ranging from routine laboratory tasks to advanced scientific discovery. Further, JASCO provides a broad portfolio of products, including state-of-the-art HPLC, UHPLC, and supercritical fluid chromatography (SFC / SFE) systems, as well as cutting-edge detectors, columns, accessories, and specialized software to facilitate versatile workflows. Notably, their chromatography systems are widely used for various applications including analysis and purification of proteins, biomolecules, and chiral compounds. In addition to instruments, JASCO supports its clients through comprehensive application support, method development, and global service networks.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1958 |
| Number of Employees | 501-1,000 |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In July 2024, JASCO entered into a partnership with Bioz Join to enhance visibility into the usage and application of its products and encourage researchers to improve and refine their experiments.
To know more about the recent initiatives of JASCO and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
4. MilliporeSigma
Company Overview
MilliporeSigma, a brand of Merck is globally recognized for its innovation in chromatography solutions, addressing the diverse needs of life science, pharmaceutical, biotechnology, and academic sectors. The company offers a comprehensive range of advanced HPLC, UHPLC, and purification systems, complemented by high-performance detectors, columns, and specialized reagents designed to meet complex analytical challenges. The company’s product portfolio supports critical applications such as the separation, analysis, and purification of proteins, peptides, nucleic acids, and small molecules, enabling researchers to tackle both routine and advanced scientific tasks. MilliporeSigma also provides expert application support, method development services, and a global technical and service network. This commitment to quality and reliability empowers customers to achieve exceptional standards in accuracy, efficiency, and data integrity throughout their research and quality assurance processes.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1951 |
| Number of Employees | 5,001 - 10,000 |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In January 2025, Merck Life Science announced the expansion of its manufacturing facility in Pennya, Bengaluru by adding additional 50,000 square feet area. This expansion strengthened the company’s manufacturing capabilities for tangential flow filtration (TFF) and chromatography purification systems.
To know more about the recent initiatives of MilliporeSigma and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
5. Revvity
Company Overview
Revvity is a US-based life sciences and diagnostics company which was formed in 2023, following the separation of PerkinElmer's life sciences and diagnostics segments. The company is engaged in the development of spectroscopic instruments with high sensitivity and reliability. Moreover, Revvity has a robust product portfolio of chromatography systems, which includes HPLC, UPLC, liquid chromatography mass spectrometry (LC/MS), gas chromatography, gas chromatography mass spectrometry (GC/MS) for the identification and quantification of small molecules, biologics, food safety and other industrial applications.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 2023 |
| Number of Employees | 10,001+ |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In September 2025, Revvity participated in the Baird Global Healthcare Conference 2025 for presenting its recent performance and future outlook. The company reported growth in its consumables and software segments in the second quarter.
In the same month, the company also participated in the Wells Fargo 20th Annual Healthcare Conference 2025, presenting its strategic position in the industry, while emphasizing on its commitment to innovation and operational efficiency for long-term growth.
To know more about the recent initiatives of Revvity and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
6. Sartorius
Company Overview
Headquartered in Germany, Sartorius claims to be a pioneer in advancing biotechnology research and bioprocessing technologies. The company provides a comprehensive portfolio of chromatography consumables and integrated systems to meet the needs of diverse industries worldwide, including pharmaceuticals, biopharmaceuticals, and life sciences research. Moreover, Sartorius specializes in process chromatography solutions that enable efficient large-scale purification and separation, supporting various biopharmaceutical manufacturers in ensuring product quality, scalability, and process robustness. By focusing on innovative chromatography consumables and scalable process chromatography solutions, Sartorius continues to advance the efficiency and precision of biopharmaceutical purification and separation processes globally.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1870 |
| Number of Employees | 10,001+ |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In April 2025, Sartorius completed the acquisition of Danaher’s FortéBio, SoloHill and chromatography hardware and resins businesses for an amount of USD 825 million. This acquisition positions Sartorius at the forefront of the bioprocessing and bioanalytics sectors.
In March 2025, Sartorius announced investment in its Bengaluru plant to expand its annual manufacturing and testing capacity for Resolute Flowdrive chromatography systems and support large-scale biopharmaceutical purification globally.
To know more about the recent initiatives of Sartorius and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
7. Shimadzu Scientific Instruments
Company Overview
Shimadzu Scientific Instruments is a US-based company specializing in the manufacturing of innovative medical devices, analytical and measuring instruments, and industrial machinery. The company is focused on advancing human health, safety, societal security, and industrial processes with rigorous quality control. Further, Shimadzu Scientific Instruments provides a comprehensive range of chromatography solutions, including preparative systems for large-scale purification and advanced software for sophisticated data handling and analysis. These cutting-edge analytical and preparative chromatography technologies enable precise separation and purification across various industries such as pharmaceuticals, environmental monitoring, food safety, and chemicals.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1975 |
| Number of Employees | 501-1,000 |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Column Offered |
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| Type of Stationary Phase Offered |
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| Format of Stationary Phase |
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| Type of Analyte Separated |
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| Application Area |
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Recent Developments:
In May 2025, Shimadzu announced enhancements to its gas chromatography systems, Brevis GC-2050, with the primary focus on operational efficiency and environment sustainability.
In March 2025, Shimadzu established a new R&D lab in Boston focused on advancing chromatography and mass spectrometry technologies, thereby accelerating pharmaceutical research and innovation.
To know more about the recent initiatives of Shimadzu Scientific Instruments and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
8. Thermo Fisher Scientific
Company Overview
Thermo Fisher Scientific is an international firm dedicated to accelerating life sciences research by solving complex analytical challenges and developing innovative technologies for its clients. The company claims to operate in over 600 locations through its subsidiaries, including Applied Biosystems, Invitrogen, Patheon and Unity Lab Services. The firm develops products for applications in various fields, such as life sciences, clinical, diagnostic, industrial and applied sciences. In addition, the company provides a wide variety of chromatography instruments, software solutions and consumables to cater to the needs of the pharmaceutical, biopharmaceutical and food industries.
| Key Parameters | Specifications |
| Company Logo | ![]() |
| Year of Establishment | 1962 |
| Number of Employees | 10,001+ |
| Headquarters | ![]() |
Chromatography Instruments Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Chromatography Consumables Portfolio
| Parameter | Details |
| Type of Chromatography Systems / Instruments Offered |
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| Type of Chromatography Consumables Offered |
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| Application Area |
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Recent Developments:
In February 2024, Thermo Fisher Scientific launched a new ion chromatography instrument, Thermo Scientific™ Dionex™ Inuvion™ Ion Chromatography (IC) system, to improve overall reliability, efficiency and functional adaptability for laboratories.
To know more about the recent initiatives of Thermo Fisher Scientific and other ion chromatography instrument manufacturers and consumables manufacturers, access full report.
The above article features eight chromatography companies selected from a pool of over 140 players that we have compiled. If you're interested, you can download the Sample Report on this topic by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com.
Sources
1. https://www.agilent.com/about/newsroom/presrel/2025/12jun-ca25020.html
2. https://www.agilent.com/about/newsroom/presrel/2025/30may-ca25018.html
3. https://www.agilent.com/about/newsroom/presrel/2025/15may-gp25008.html
4. https://www.agilent.com/about/newsroom/presrel/2025/08may-ca25013.html
5. https://investors.bio-rad.com/press-releases/news-details/2025/Bio-Rads-Management-to-Host-Investor-Meetings-During-Jefferies-Global-Healthcare-Conference/default.aspx
6. https://www.bio-rad.com/en-in/process-separations/news/bio-rad-launches-nuvia-wprime-2a-media-for-biomolecule-purification?ID=Bio-Rad-Launches-Nuv_1736287564
7. https://www.newswire.com/news/jasco-and-bioz-join-forces-for-a-second-year-to-empower-the-scientific-22385448
8. https://www.bioprocessintl.com/deal-making/milliporesigma-opentrons-to-automate-assay-kits
9. https://www.investing.com/news/transcripts/revvity-at-baird-global-healthcare-conference-steady-growth-amid-challenges-93CH-4232364
10. https://www.investing.com/news/transcripts/revvity-at-wells-fargo-conference-navigating-growth-amid-challenges-93CH-4221896
11. https://chemanager-online.com/en/news/sartorius-closes-danaher-acquisition
12. https://www.pharmabiz.com/NewsDetails.aspx?aid=176870&sid=2
13. https://www.labmanager.com/shimadzu-s-brevis-gc-2050-enhancements-offer-efficiency-and-sustainability-33977
14. https://www.biospectrumasia.com/news/107/25804/japans-shimadzu-scientific-instruments-opens-boston-location-of-rd-centre.html