Top 10 Cold Chain Packaging Companies for Pharmaceuticals

Published: January 2024


These players are engaged in offering cold chain secondary packaging solutions (containers / shippers) for the transportation of temperature-sensitive pharmaceuticals. We analyzed more than 70 cold chain packaging companies providing containers / shippers for the transportation of temperature-sensitive pharmaceuticals. In this article, discover the 10 leading companies and their portfolios in the cold chain market for pharmaceuticals.


Advancements in the food, healthcare and chemical industries have prompted the requirement of advanced packaging solutions for storing, handling and transporting products. Owing to the temperature-sensitive nature of certain products such as fresh agricultural products, flowers, seafood, frozen food, photographic films and pharmaceutical chemicals / products, the need for temperature-controlled packaging has emerged in the packaging industry. Therefore, in order to extend the shelf life and maintain the stability and integrity of products during shipment, several cold chain companies are actively engaged in developing and offering temperature-controlled packaging solutions. In the recent years, this approach has evolved significantly to become one of the most preferred methods for healthcare products including biologics, tissues, organs, cell and gene therapies, vaccines and blood.

Despite the potential of such solutions in safe transportation of pharmaceuticals, there are still some challenges with the packaging and temperature monitoring of pharmaceuticals in cold chain storage, including risk of damage, contamination, and disrupted temperature control. In this context, cold chain solutions providers are actively exploring advanced hybrid solutions, involving the use of packaging integrated data loggers for improved visibility and efficient tracking of pharmaceutical shipment in the cold chain industry, posing as a promising alternative over conventional packaging solutions.

Roots Analysis has conducted an exhaustive study on Cold Chain Market for Pharmaceuticals featuring the current market landscape and future opportunity for the cold chain packaging companies providing containers / shippers, over a span of 12 years.

Table of Contents

The top 10 cold chain packaging companies providing containers / shippers (mid-sized and large companies) are listed below (in alphabetical order):

Table 1: List of Top 10 Cold Chain Packaging Companies Providing Containers / Shippers

S.No. Cold Chain Containers / Shippers Providers   Year of Establishment                    Number of Employees    Location of Headquarters   
1 Cold Chain Technologies 1967 501-1,000 US
2 Cryopak 1990 201-500 US
3 Csafe 1979 501-1,000 US
4 EMBALL'ISO 1990 51-200 France
5 Intelsius 1998 51-200 UK
6 Nordic Cold Chain Solutions 2004 51-200 US
7 Peli BioThermal 2000 51-200 US
8 SEE 1960 10,001+ US
9 Sofrigam 1979 51-200 France
10 Sonoco Thermosafe 1946 1,001-5,000 US

 

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Discover the Details on 10 Cold Chain Packaging Companies Providing Containers / Shippers

This article highlights the top 10 players to watch out for in this industry. These companies were chosen based on their prominence in the industry and company size (mid-sized and large). It is essential to note that the selection of top players can differ substantially according to the defined criteria.

1. Cold Chain Technologies, an Insulated Packaging Solutions Provider for the Life Sciences Industry

Cold Chain Technologies - Cold Chain Packaging

Cold Chain Technologies is a US-based company that claims to have more than 50 years of experience in the life sciences supply chain domain. The company offers reusable and single-use thermal packaging solutions for the shipment of temperature-sensitive materials. 

Cold Chain Technologies offers both active as well as passive solutions fabricated from expanded polystyrene, polyurethane material, vacuum insulated panel and phase change material. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants
  • Freezers and Refrigerators

Additional Services for Containers / Shippers: Design services, reuse services, and track and trace services

Recent Developments:

In October 2023, the company acquired Exeltainer for expanding its footprint and life sciences portfolio of thermal packaging solutions

In January 2023, the company expanded its product portfolio with the launch of CCT TheraShield an advanced, reusable thermal packaging solution with applications in cell and gene therapy sector. Further information related to the product and services portfolios of cold chain packaging companies is available in the full report.
 

2. Cryopak, a Designer and Manufacturer of Cold Chain Packaging Solutions and Refrigerants for Applications in the Healthcare Industry

Cryopak - Cold Chain Packaging

Cryopak is a US based company, engaged in designing and manufacturing of cold chain packaging systems used for the shipment of temperature-sensitive products pertaining to the pharmaceutical, biotech and life sciences industries. In addition to these industries, the company provides cold chain solutions to food and electronics industries. Interestingly, the company is also engaged in the design and manufacturing of self-powered, reliable, and technically advanced data loggers for the purpose of monitoring temperature sensitive shipments. It is worth highlighting that the firm is a part of Integreon Global companies, collectively aimed at ensuring product integrity and safety.

Cryopak offers active as well as passive packaging solutions, which are essentially fabricated using expanded polystyrene, extruded polyisocyanurate, polyurethane and vacuum insulated panels. These materials aid in maintaining the temperature inside the packaging by restricting the exchange of heat. The different types of products offered by the company include:

  • Containers / Shippers
  • Refrigerants

Additional Services for Containers / Shippers: Design services, reuse services and track and trace services

Recent Developments:

In April 2023, the company exhibited its latest innovative and sustainable thermal packaging solutions at Asembia’s AXS23 Summit at the Wynn & Encore Las Vegas.

In March 2023, the company entered into a joint venture agreement with M. Chasen & Son in order to introduce full line of sustainable, recyclable and compostable shipping solutions. Further information related to the product and services portfolio of cold chain packaging companies is available in the full report.
 

3. CSafe, an End-to-End Cold Chain Shipping Solutions Provider Collaborating to Serve the Pharmaceutical Needs

CSafe - Cold Chain Packaging

CSafe is a US based company that claims to offer a comprehensive suite of thermal shipping solutions for pharmaceutical cold chain shipping. In this context, the company delivers both active and passive segments of industry leading packaging products. Interestingly, the company is also engaged in providing thermal packaging solutions that can be customized to cater to the size, duration, and temperature requirements of the customers. It is worth mentioning that, in December 2021, CSafe acquired Softbox Systems to further expand its passive cold chain packaging product portfolio.

CSafe offers active as well as passive solutions which are essentially fabricated from polyurethane, vacuum insulated panels and phase change materials. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants
  • Freezers and Refrigerators

Additional Services for Containers / Shippers: Design services, reuse services and track and trace services

Recent Developments:

In May 2023, the company entered into a partnership with Modality Solutions in order to provide an integrated solution by combining latter’s cold chain engineering capabilities with CSafe's shipping solutions.

Further, in May 2023, the company initiated a collaboration with Central Pharma in order to provide expanded supply chain options for cell and gene therapy products across multiple stages of development.

In January 2023, the company expanded its digital ecosystem with the launch of CSafe Connect, a cloud-based portal for placing, tracking, and managing shipments in real-time along with a new TracSafeTM line of data loggers. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

4. EMBALL'ISO, an Experienced High-performance, Temperature-controlled Packaging Systems Provider

EMBALL’ISO - Cold Chain Packaging

EMBALL’ISO is a France based company that provides passive high-performance isothermal packaging solutions for the storage and transportation of pharmaceuticals. For more than 30 years, the company has supported pharmaceutical laboratories and logistic companies with the aim of managing and controlling cold chain risks. Further, the company claims to be an expert in providing preconditioning, rental, and reverse logistics services for a sustainable cold chain. It is worth mentioning that the company operates across four continents, with nine manufacturing sites, 13 additional service centers, and collection points in more than 80 countries in order to facilitate the supply of packaging solutions.

EMBALL’ISO offers active as well as passive solutions which are essentially formed from polyurethane, vacuum insulated panel and phase change material. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants
  • Freezers and Refrigerators

Additional Services for Containers / Shippers: Design services, reuse services, rental services and track and trace services

Recent Developments:

In June 2023, the company participated in various international exhibitions in order to exhibit its cold chain services and product offerings. These include:

  • LogiPharma, held in Singapore.
  • CPHI China, held at the Shanghai New International Expo Centre (SNIEC) in Shanghai, China.
  • Transport Logistics China, held in Shanghai, China.
  • Temperature Controlled Logistics IQPC, held in Germany, Frankfurt.
  • FCE Pharma, held in Sao Paulo, Brazil.

In March 2023, the company entered into a distribution partnership with Hankyu Hanshin Express to support the latter’s cold chain service portfolio by offering transportation that is environment-friendly and ensuring quality and safety of the products in transit. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

5. Intelsius is Designing Intelligent, Sustainable and Pre-qualified Packaging Solutions

Intelsius - Cold Chain Packaging

Intelsius is a UK based company focused on designing and manufacturing sample transport and temperature-controlled packaging. The company thrives on the green mission, aimed at reducing the global carbon footprint. As a part of this mission, the company has undertaken several initiatives and responsibilities to ensure future success without compromising the environment. Further, the company has collaborated with several environmental charities.

Intelsius offers passive solutions which are fabricated using expanded polystyrene, expanded polypropylene, vacuum insulated panel and phase change material. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants
  • Mailers

Additional Services for Containers / Shippers: Design services, reuse services, rental services and track and trace services

Recent Developments:

In June 2023, the company attended the Temperature Control and Logistics 2023 summit in Frankfurt, where it showcased its wide range of cold chain packaging solutions.

In May 2023, Intelsius entered into a partnership with A2Cargo in order to utilize former’s validated and qualified packaging solutions for time and temperature sensitive shipments. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

6. Nordic Cold Chain Solutions, an Emerging Leader in Cold Chain Landscape, Offering a Wide Range of Cold Chain Products and Services

Nordic Cold Chain Solutions - Cold Chain Packaging

Nordic Cold Chain Solutions is a US based company, engaged in providing high quality cold chain solutions to the pharmaceutical industry for over a decade. It is worth highlighting that the company partners with its clients to create custom solutions in order to cater to their expectations for temperature-controlled packaging and manufacturing. Further, the company utilizes recyclable materials, demonstrating its commitment towards the environment.

Nordic Cold Chain Solutions offers passive solutions which are made up of expanded polystyrene and polyurethane materials. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants
  • Mailers

Additional Services for Containers / Shippers: Design services and track and trace services

Recent Developments:

In May 2023, the company appointed Andy Bolton as the president and chief executive officer of Nordic Cold Chain Solutions.

Nordic Cold Chain Solutions is currently focused on making breakthrough developments in the cold chain market. In this context, the company has developed a new line of Frozen Shippers that are specifically designed for the distribution of vaccines. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

7. Peli Biothermal, Widest Range of Temperature-controlled Packaging, Rental and Leasing Service Solutions Provider

Peli BioThermal - Cold Chain Packaging

Peli BioThermal is a US based company, which claims to be the first cold chain packaging solutions provider that offers a comprehensive portfolio of single-use and reusable thermal packaging solutions. The company is dedicated to developing innovative products that are designed to fulfil the complex requirements of the life sciences industry. Further, the company provides a services network, which includes consultation, support, engineering, and deployment for any challenges associated with cold chain distribution.

Peli Biothermal offers passive solutions which are fabricated from expanded polystyrene, vacuum insulated panel and phase change material. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Refrigerants

Additional Services for Containers / Shippers: Design services, reuse services, rental services and track and trace services

Recent Developments:

In June 2023, the company announced the establishment of a new service network station in Valencia, California for the purpose of discovering new therapies and distribution of packaging products.

In March 2023, the company announced an expansion of its reusable Credo shipper portfolio to support the safe transport of temperature-sensitive biologics and cell and gene therapies to the patients. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

8. SEE, Pledging towards 100% Sustainable Packaging Materials for Food and Healthcare-related Packaging

SEE - Cold Chain Packaging

SEE is a US based company that claims to be engaged in creating a more environmentally, socially, and economically sustainable future for the packaging industry. For this, the company actively collaborates with its customers to solve their resource challenges by delivering new solutions derived from its industry knowledge and expertise. It is worth highlighting that the company has pledged to design 100% packaging materials that can be recycled or reused by 2025, along with zero carbon emissions in its operations by 2040.

SEE offers passive solutions which are fabricated using vacuum insulated panel and polyurethane materials. The different types of products offered by the company include:

  • Containers / Shippers

Additional Services for Containers / Shippers: Design services and reuse services

Recent Developments:

In June 2023, the company participated in Bank of America Non-Deal Roadshow in Tokyo, Japan in order to discuss its strategy to drive high-quality growth.

Additionally, in June 2023, the company participated in William Blair 43rd Annual Growth Stock Conference –Chicago, US with the aim of discussing its approach to manage high-quality growth. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

9. SOFRIGAM, a Pioneer in Cold Chain Industry Offering Innovative Solutions and Technologies for Packaging and Monitoring of Cold Chain Shipments

SOFRIGAM - Cold Chain Packaging

SOFRIGAM is a France based company having more than 40 years of experience in developing and offering isothermal and refrigeration solutions for the transport of temperature-sensitive pharmaceutical products. In this context, the company has designed high quality cold chain shipping packaging solutions that can meet the demands and requirements of pharmaceutical as well as chemical industries. The company’s primary aim is to help improve the efficacy of medicines by facilitating their transportation across the world and support its customers with an optimized, environmental-friendly cold chain solution.

SOFRIGAM offers active as well as passive solutions which are essentially fabricated from vacuum insulated panel and expanded polystyrene. The different types of products offered by the company include:

  • Containers / Shippers
  • Films / Covers
  • Freezers and Refrigerators

Additional Services for Containers / Shippers: Design services, reuse services and track and trace services

Recent Developments:

In July 2023, the company participated at the Tecnea - Cemafroid Technical Days 2023, for discussing challenges associated with last mile delivery logistics, and decarbonated cold system offered by SOFRIGAM, along with recent innovations in cold chain delivery processes.

In June 2023, SOFRIGAM participated in EUROBIKE show in Frankfurt, Germany in order to showcase its novel, zero emission cold chain delivery solution for urban logistics. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.
 

10. Sonoco Thermosafe, a Strategic Cold Chain Packaging Partner for Temperature Sensitive Pharmaceuticals, Biologicals and Vaccines

Sonoco Thermosafe - Cold Chain Packaging

Sonoco Thermosafe is a US based company that is engaged in offering temperature-controlled packaging solutions for the secure and effective transport of medicines, biologics, vaccines, and other temperature-sensitive goods. In this context, the company provides designing and thermal testing of cold shipping boxes. It is worth mentioning that the company claims to have an experience of over 120 years in this domain and it is focused on offering better packaging solutions, products and services and digital tools.

Sonoco Thermosafe offers passive solutions which are made up of expanded polystyrene, polyurethane, expanded polypropylene, fiberboard material and vacuum insulated panel. The different types of products offered by the company include:

  • Containers / Shippers
  • Refrigerants

Additional Services for Containers / Shippers: Design services, reuse services, rental services and track and trace services

Recent Developments:

In January 2023, the company attended the BioPharma & Lifesciences Connected Live event in Ireland, in order to exhibit its full range of temperature-controlled packaging solutions designed to ensure safe and efficient transportation of pharmaceuticals, biologics, vaccines and other temperature-sensitive products. Further information related to the product and service portfolio of cold chain packaging companies is available in the full report.

What About the Other Cold Chain Packaging Companies Providing Containers / Shippers?

The above presentation features 10 cold chain packaging companies supplying containers / shippers selected from a pool of over 70 product providers that we have compiled. If you are interested, you can download the Sample Report on “Cold Chain Market for Pharmaceuticals” by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com.

About Author

Dhriti_Gulati

Dhriti is a Senior Business Analyst, working as an integral part of the Roots Analysis team since 2021. Passionate about the intersection of science and industry, she holds a Bachelor’s degree in biotechnology from a renowned university. Possessing keen interest in the pharma domain, Dhriti initiated her professional journey with a strong academic foundation. Her passion to learn more about the emerging trends and technological advancements has enabled her to provide comprehensive insights through syndicate reports and consulting. The unique blend of scientific knowledge and business acumen has enabled her to provide insightful analysis in the ever-evolving life-sciences domain. Till date, she has earnestly contributed to over 6 in-depth market research reports on trending topics, ranging from non-hormonal therapies for women health, oligonucleotide synthesis, RNAi therapeutics and technologies, cell therapy manufacturing to next deep learning in drug discovery and diagnostics.

Source1: Exeltainer
Source2: https://www.coldchaintech.com/news-item/cold-chain-technologies-acquires-exeltainer-expanding-its-presence-in-europe-and-latin-america
Source3: https://www.coldchaintech.com/news-item/cold-chain-technologies-expands-portfolio-to-provide-solutions-for-cell-and-gene-therapy-industry-cct-therashield
Source4: https://www.cryopak.com/cryopak-and-m-chasen-son-inc-form-joint-venture/
Source6: https://csafeglobal.com/blog/2023/01/10/csafe-expands-digital-ecosystem-csafeconnect-tracsafe/
Source7: https://www.emballiso.com/en/news-isothermal-packaging/606-emball-iso-starts-supporting-hankyu-hanshin-express
Source8: https://a2cargo.com/en/partnership-with-dgp-intelsius-supplier-of-validated-packaging-systems-for-pharma-logistics-industry/
Source9: https://nordiccoldchain.com/nordic-cold-chain-solutions-prepared-for-covid-vaccine-distribution/
Source10: https://pelibiothermal.com/news/peli-biothermal-opens-full-service-network-station-southern-california

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