Rheumatoid Arthritis: Beyond TNF Inhibitors

Roots Analysis has announced the addition of the “Rheumatoid Arthritis Market: Beyond TNF Inhibitors, 2016-2026” report to its list of offerings. The report provides a comprehensive analysis of the current market landscape of therapies for the treatment of rheumatoid arthritis, specifically, non-tumor necrosis factor (TNF) inhibitors.

Neha Agarwal, the principal analyst, stated, “Over the last three decades, the treatment paradigm for rheumatoid arthritis has shifted from drugs that offer mere symptomatic relief to strategies that aim to slow down / arrest structural joint damage and disease activity. This has led to the emergence of several novel types of therapies and drug classes, such as JAK inhibitors and anti-interleukins.”

One of the primary objectives of the study was to project the growth of this market segment and predict how it is likely to evolve over the coming decade. In addition, the report includes:

• An overview of the current state of the market with respect to available drug classes, key players, phase of development of pipeline products, route of administration used, type of molecule and type of therapy.
• In-depth analyses, featuring schematic representations, which highlight the distribution of pipeline molecules, the landscape of industrial developers and the geographical distribution of the companies involved in this domain.
• Detailed profiles of drugs that have been recently (post-2010) launched or are in the late stages of development (phase III and above).
• Information on the mechanisms of action of novel non-TNF inhibitor drugs, which are being investigated as potential treatment options for rheumatoid arthritis.
• A review of the clinical development programs of late stage product candidates (active comparator trials, important primary endpoints and scale), including a comparative analysis of the key clinical trial endpoints for drugs that are already marketed or are in phase III of development.
• A detailed analysis of the partnerships established between stakeholders in the industry over the past few years.
• A discussion on emerging trends and the popularity of non-TNF inhibitors on social media.

Agarwal further stated, “In order to address the growing concerns related to patient compliance, drug developers have shifted their focus towards the development of oral drugs. Over 50% of molecules in the current pipeline are being developed for oral administration. In addition, combination therapies involving existing drug classes, have been shown to be associated with better outcomes as compared to their use as monotherapies.”

Key players, having marketed / late stage product candidates, that have been covered extensively in the study include:

• AbbVie
• Amgen
• Astellas
• Biogen Idec
• Bristol-Myers Squibb
• Can-Fite BioPharma
• Chugai Pharmaceuticals
• Daiichi Sankyo
• Eli Lilly
• Galapagos
• Genentech
• Gilead Sciences
• GlaxoSmithKline
• Immune Response BioPharma
• Incyte Corporation
• Johnson & Johnson
• Pfizer
• Regeneron Pharmaceuticals
• Roche
• Sanofi-Aventis

About Roots Analysis

Roots Analysis is a global life sciences market research, competitive intelligence, and strategic consulting firm specializing in the pharmaceutical, biotechnology, medical devices and healthcare industries. Founded in 2013, we have served 1,500+ global clients, from startups to Fortune 500 companies, helping them evaluate market opportunities, assess competition, and make data-driven business decisions. We also provide dedicated solutions to academic institutes, universities, non-profit organizations and other non-industry players.

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