According to a recently published report by Roots Analysis, the increasing number of approvals of cell therapies and a sharp rise in associated clinical trials is driving the cell therapy media and consumables market growth
The global cell therapy consumables and cell therapy media market size was estimated at USD 1.2 billion in 2023 and is expected to reach over USD 4.5 billion by 2035, growing at a CAGR of 11.7% in the forecast period 2023-2035.
Cell therapy refers to transplantation of healthy cells to restore impaired tissues or functions. Novel cell therapies are being developed for potential application across several therapeutic areas, including oncological disorders, autoimmune disorders, and neurological disorders. Till date, 61 non-genetically modified cell therapies have been approved, across the globe. Further, over 2,000 cell therapies are currently being developed across various stages of development. However, multiple challenges related to operations, cost, and manufacturing of cell therapies hinder patient welfare. In addition, the industry is regulated through the implementation of stringent guidelines. In pursuit of both time and cost savings, as well as to mitigate the regulatory challenges associated with manufacturing of cell therapy consumables, around 90% of the cell therapy developers prefer to outsource culture media, kits, reagents and extracellular matrices from consumable providers. The majority of cell therapies demonstrate high effectiveness in clinical studies, however, witness major hurdles during commercialization. This is due to the inability of developers to maintain product consistency at a commercially viable cost. The variability rises from the use of animal or human derived supplements, such as cell culture media, which have poorly defined composition and are inconsistent. This has led to a paradigm shift from serum-containing media to serum free and xeno free compositions, which are chemically defined and offer homogeneity.
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Various factors contribute to the market growth of cell therapy consumables and cell therapy media market. These factors include the growing incidence of chronic therapeutic indications, such as cancer and rare disorders, and subsequent surge in the demand for novel cellular therapies. Cell therapies have demonstrated vast potential to treat rare disorders, which were previously considered incurable. Owing to the increasing number of cell therapy approvals, rise in associated clinical studies, the demand for cell therapy consumables is likely to witness significant surge. Further, the increasing adoption of chemically defined, animal component free media is also contributing to the sustained growth of the industry.
One of the primary restraints associated with this industry includes standardization challenges associated with the manufacturing of cell therapies. Conventionally, animal derived supplements such as FBS (Fetal Bovine Serum) containing basal media was widely used for cell proliferation and maintenance. However, these products pose a risk to patient safety due to its heterogeneous composition and risk of pathogen transmission. Further, for large scale manufacturing of cell therapies, the FBS supply chain poses as a limiting factor. In addition, stringent regulatory guidelines obstruct the growth of the industry. The high cost and low success rate of cell therapies restricts new entrants from exploring opportunities within the market.
Despite the challenges, several growth factors continue to drive the cell therapy media, kits, reagents and surfaces market forward. One notable factor is the growing number of cell therapy focused clinical trials. Nearly 970 CAR-T cell therapies are currently being developed, from preclinical to pre-registration stages. It is worth highlighting that of these therapies, 95% are targeted for the treatment of oncological disorders. With the increasing prevalence of cancer, the demand for such therapeutic interventions is anticipated to surge. This is creating lucrative market opportunities for cell therapy consumable providers. Further, as research in this domain is accelerating, the demand for research-grade consumables is also poised to elevate. Given the advantages of chemically defined, serum free and xeno free consumable products, combined with regulatory stringency, the opportunity associated within this market is expected to rise.
The cell culture consumables and cell culture media market report also includes detailed profiles of key players (listed below) that offer liquid biopsy products:
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Gaurav Chaudhary
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