Published: December 2023
According to a recently published report by Roots Analysis, the growing complexities with click-chemistry and demand for bioconjugation capabilities is driving the conjugation and labeling services market growth
The global conjugation and labeling services market is anticipated to grow at a CAGR of 10.2% from 2023-2035, reaching USD 2.9 billion by 2035.
The growing interest of various stakeholders in conjugated and labeled molecules for therapeutic and diagnostic applications had led to a surge in demand for these complex molecules. The conjugates / labels incorporated in the molecules are known to offer target specificity, bioavailability, improved pharmacokinetic property and membrane permeability. Moreover, these bioconjugates support the robust and sensitive detection of the target molecule of interest. The construction of homogenous bioconjugates require multidisciplinary expertise and advanced bioconjugation technologies that can be accessed through service providers. The service providers tend to be equipped with established methodologies, along with a wide range of reagent systems and conjugates required for the chemical modification of different biomolecules. These factors together will be responsible for market growth through increased outsourcing of protein labeling, antibody labeling and antibody conjugation services to the CROs.
Browse 65+ figures and 75+ market data tables spread across 190+ pages and detailed Table of Content on “Conjugation and Labeling Services Market (Focus on Protein Labeling, Peptide Labeling, Small Molecule Conjugation and Antibody Conjugation) by Type of Molecule Supported, Type of Molecular Conjugate / Label and Key Geographical Regions: Industry Trends and Global Forecasts, 2023-2035” here: https://www.rootsanalysis.com/reports/conjugation-and-labeling-services-market.html
The bioconjugation field has witnessed several advancements and garnered significant attention over the last few years owing to its potential in the therapeutic, diagnostic and theranostic areas. Conjugated therapeutics have demonstrated their superiority over conventional drug products for the treatment of various diseases. They have been reported to increase the drug targeting, therapeutic window and lower the side-effects in the patient’s body. The growing bioconjugated drugs pipeline is expected to translate into huge business opportunities for contract service providers. These service providers possess the required technical expertise to mitigate the click-chemistry related concerns observed during the conjugation process. Further, these players offer solutions for conjugation of various conjugates (including enzymes, photoreactives, isotopes and quantum dots), with the molecule of interest and have dedicated facilities to carry out complex conjugation operations. Therefore, in order to mitigate the process-related complexities, companies engaged in this domain are outsourcing their operations to contract service providers.
Despite several advantages, the conjugation and labeling services domain still faces certain limitations. For instance, maintenance of quality of the conjugated molecule poses a concern amongst service providers. The conjugation process may lead up to formation of heterogeneous mixtures of unconjugated, over-conjugated and under-conjugated molecules, due to similarity in different functional groups of various molecules (such as protein) present in the mixture. Therefore, owing to non-specific conjugation, the probability of usage of such products as therapeutics can be reduced. Moreover, significant efficacy variation between different batches of conjugated products poses a concern. The contract service providers need to ensure the formation of homogenous mixture and batch quality. Apart from availability of specialized technologies, strict regulatory guidelines, highly skilled professionals, high capital and need for conjugates, such as radioactive isotopes and quantum dots, also pose a restraint.
Despite the challenges, several growth factors continue to drive the conjugation and labeling services market forward. The significant rise in popularity of conjugated biomolecules for therapeutics and diagnostics (including bioimaging) has led to substantial growth of the conjugation and labeling services market in recent years. Such service providers also offer a quick turnaround time after the receipt of the molecule, for a lower cost. Specifically, the availability of low-cost outsourcing options in emerging geographies has led to a noteworthy rise in outsourcing budgets. With the increasing dependency on contract service providers, the need for cost effective and high-quality operations is likely to rise. Further, in order to meet the growing requirements of their clients and improve their capabilities, several contract service providers have entered into partnerships with stakeholders in order to provide end-to-end solutions for their clients’ product development needs.
The conjugation and labeling services market report also includes detailed profiles of key players (listed below) that offer services for conjugation and labeling of biomolecules:
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