Upon realizing the potential of this route of administration, industry stakeholders have initiated several R&D efforts focused on exploiting the use of intranasal therapeutics as an effective modality for the treatment of various disorders.
Roots Analysis has announced the addition of “Nasal drug delivery Market, 2023-2035” report to its list of offerings.
Over the last few years, pharmaceutical companies have expanded their focus to devise novel intranasal drug delivery systems for the development of therapeutic candidates. This can be attributed to its numerous advantages such as, ease of administration, avoidance of first pass-metabolism and rapid onset of action, potentially making it an appealing alternative to other drug delivery systems.
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Close to 60% of the pipeline candidates are currently being evaluated in clinical stages; of these, more than 15 drugs are in phase II studies. It is also worth highlighting that majority of the therapy candidates (55%) are small molecules.
Of the total, 20% companies were established in this domain since 2016. Further, around 54% of the industry stakeholders are small companies. In addition, majority (80%) of the intranasal therapeutic developers are based in North America, primarily in the US.
40% of the intranasal drug delivery systems are available in unit and multi dose type of systems. This is followed by 20% intranasal drug delivery systems have metered dose type of system. It is worth highlighting that majority of the intranasal drug delivery systems are (53%) are present in liquid type of dosage form.
Clinical research activity, in terms of number of trials registered, is reported to have increased over the last five years. Of the total number of trials, close to 65% have already been completed, while 16% are active and still recruiting patients.
Owing to the rising research efforts of several industry and non-industry players engaged in this domain, close to 56% of patent applications have been filed post 2014. It is worth noting that, 235 patents related to nasal drug delivery were filled / granted in the US alone.
Maximum number of partnerships were established in 2020, indicating a recent rise in the interest of players engaged in this domain. It is worth mentioning that, majority (19%) of the deals were instances of product commercialization / distribution agreements, followed by technology utilization agreements (17%).
Of the total amount invested, over USD 1 billion was raised through debt financing, representing over 50% of the overall funding activity in this domain. Further, 11 instances of other equity were reported, wherein players collectively received funds worth more than USD 0.7 billion.
The market will be primarily driven by sales of intranasal small molecule therapeutics (91%), followed by those developed as biologics (9%). Further, intranasal therapies targeting dry eye diseases are expected to capture the dominant share (64.8%) of the market (in terms of sales-based revenues); this trend is unlikely to change in the foreseen future as well.
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The research also includes detailed profiles of the companies (listed below) engaged in developing nasal drug delivery; each profile features an overview of the company, its financial information (if available), details on product portfolio, recent developments, and an informed future outlook.
You Can Download Free Sample PDF Copy of This Report At:
https://www.rootsanalysis.com/reports/intranasal-therapeutics-and-drug-delivery-systems/request-sample.html
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