ADME Toxicology Testing Market

2 EXECUTIVE SUMMARY

3 INTRODUCTION
3.1. Chapter Overview
3.2. The Drug Discovery and Development Process
3.3. Introduction to Absorption, Distribution, Metabolism and Excretion (ADME) Testing
3.3.1. Absorption
3.3.2. Distribution
3.3.3. Metabolism
3.3.4. Excretion

3.4. Importance of ADME Studies in Early Stage Research
3.5. Types of ADME Studies in Discovery and Preclinical Development
3.6. Types of Assays Used in ADME Testing

3.7. Types of ADME Testing Studies
3.7.1. In Vitro ADME Testing Studies
3.7.2. In Silico ADME Testing Studies
3.7.3. In Vivo ADME Testing Studies

3.8. Key Drivers for ADME Testing Studies
3.9. Concluding Remarks

4 GUIDE TO OUTSOURCING
4.1. Chapter Overview
4.2. Outsourcing ADME Testing Services
4.3. Guiding Models for Outsourcing
4.3.1. Transactional Outsourcing Model
4.3.2. Performance-based Outsourcing Model
4.3.3. Outcomes-based Outsourcing Model
4.3.4. Phase-dependent Outsourcing Model

4.4. Selecting a Contract Research Organization (CRO) Partner
4.4.1. Key Considerations

4.5. Role of CROs in Drug Development
4.5.1. Discovery and Preclinical Research
4.5.2. Early Clinical Research
4.5.3. Late Stage Clinical Research

4.6. Benefits of Outsourcing ADME Testing Services
4.7. Risks and Challenges Associated with Outsourcing ADME Testing Services
4.8. Concluding Remarks

5 MARKET LANDSCAPE
5.1. Chapter Overview
5.2. In Vitro ADME Testing Services: List of Industry Players
5.2.1. Analysis by Year of Establishment
5.2.2. Analysis by Geographical Location
5.2.3. Analysis by Company Size
5.2.4. Analysis by Type of Service Offering
5.2.5. Analysis by Type of In Vitro ADME Assays
5.2.6. Analysis by Type of Molecule
5.2.7. Analysis by Type of Clientele
5.2.8. Logo Landscape: Distribution by Company Size and Location of Headquarters

5.3. In Silico ADME Testing Services: List of Industry Players

6 COMPANY PROFILES
6.1. Chapter Overview
6.2. Key Players based in North America
6.2.1. Albany Molecular Research (AMRI)
6.2.1.1. Company Snapshot
6.2.1.2. Financial Information
6.2.1.3. ADME Testing Specific Service Portfolio
6.2.1.4. Recent Developments and Future Outlook

6.2.2. Charles River Laboratories
6.2.2.1. Company Snapshot
6.2.2.2. Financial Information
6.2.2.3. ADME Testing Specific Service Portfolio
6.2.2.4. Recent Developments and Future Outlook

6.2.3. Pharmaceutical Product Development (PPD)
6.2.3.1. Company Snapshot
6.2.3.2. ADME Testing Specific Service Portfolio
6.2.3.3. Recent Developments and Future Outlook

6.2.4. RTI International
6.2.4.1. Company Snapshot
6.2.4.2. Financial Information
6.2.4.3. ADME Testing Specific Service Portfolio
6.2.4.4. Recent Developments and Future Outlook

6.3. Key Players based in Europe
6.3.1. Eurofins Scientific
6.3.1.1. Company Snapshot
6.3.1.2. Financial Information
6.3.1.3. ADME Testing Specific Service Portfolio
6.3.1.4. Recent Developments and Future Outlook

6.3.2. Evotec
6.3.2.1. Company Snapshot
6.3.2.2. Financial Information
6.3.2.3. ADME Testing Specific Service Portfolio
6.3.2.4. Recent Developments and Future Outlook

6.3.3. Galapagos
6.3.3.1. Company Snapshot
6.3.3.2. Financial Information
6.3.3.3. ADME Testing Specific Service Portfolio
6.3.3.4. Recent Developments and Future Outlook

6.3.4. Tecan Group
6.3.4.1. Company Snapshot
6.3.4.2. Financial Information
6.3.4.3. ADME Testing Specific Service Portfolio
6.3.4.4. Recent Developments and Future Outlook

6.4. Key Players based in Asia-Pacific
6.4.1. GVK Biosciences
6.4.1.1. Company Snapshot
6.4.1.2. ADME Testing Specific Service Portfolio
6.4.1.3. Recent Developments and Future Outlook

6.4.2. Pharmaron
6.4.2.1. Company Snapshot
6.4.2.2. ADME Testing Specific Service Portfolio
6.4.2.3. Recent Developments and Future Outlook

6.4.3. Sai Life Sciences
6.4.3.1. Company Snapshot
6.4.3.2. ADME Testing Specific Service Portfolio
6.4.3.3. Recent Developments and Future Outlook

6.4.4. Shanghai Medicilon
6.4.4.1. Company Snapshot
6.4.4.2. ADME Testing Specific Service Portfolio
6.4.4.3. Recent Developments and Future Outlook

6.4.5. Syngene International
6.4.5.1. Company Snapshot
6.4.5.2. Financial Information
6.4.5.3. ADME Testing Specific Service Portfolio
6.4.5.4. Recent Developments and Future Outlook

6.4.6. WuXi AppTec
6.4.6.1. Company Snapshot
6.4.6.2. Financial Information
6.4.6.3. ADME Testing Specific Service Portfolio
6.4.6.4. Recent Developments and Future Outlook

7 BENCHMARK ANALYSIS
7.1. Chapter Overview
7.2. Benchmark Analysis: Methodology
7.3. Benchmark Analysis: Peer Groups
7.3.1. Peer Group I
7.3.2. Peer Group II
7.3.3. Peer Group III
7.3.4. Peer Group IV
7.3.5. Peer Group V
7.3.6. Peer Group VI
7.3.7. Peer Group VII
7.3.8. Peer Group VIII

7.4. Concluding Remarks

8 MERGERS AND ACQUISITIONS
8.1. Chapter Overview
8.2. In Vitro ADME Testing Services: Mergers and Acquisitions
8.2.1. Cumulative Year-wise Trend
8.2.2. Geographical Activity
8.2.3. Ownership Change Matrix
8.2.4. Most Active Players: Analysis by Number of Acquisitions
8.2.5. Key Value Drivers
8.2.6. Key Acquisitions: Deal Multiples

9 REGULATORY RECOMMENDATIONS AND GUIDELINES
9.1. Chapter Overview
9.2. Regulatory Guidelines Issued by International Regulatory Agencies
9.2.1. The International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use
9.2.2. World Health Organization (WHO)
9.2.3. Organisation for Economic Co-operation and Development (OECD)

9.3. Regulatory Guidelines Issued by Regional Regulatory Agencies
9.3.1. United States Food and Drug Administration (USFDA), US
9.3.2. European Medicine Agency (EMA), Europe
9.3.3. Ministry of Health, Labour and Welfare (MHLW), Japan

9.4. In Vitro ADME Testing Service Providers: Information on Regulatory Approval

10 MARKET FORECAST
10.1. Chapter Overview
10.2. Forecast Methodology and Key Assumptions
10.3. Overall In Vitro ADME Testing Services Market, 2019-2030
10.4. In Vitro ADME Testing Services Market: Distribution by Regions, 2019-2030
10.4.1. In Vitro ADME Testing Services Market in North America, 2019-2030
10.4.1.1. In Vitro ADME Testing Services Market in the US, 2019-2030
10.4.1.2. In Vitro ADME Testing Services Market in Canada, 2019-2030

10.4.2. In Vitro ADME Testing Services Market in Europe, 2019-2030
10.4.2.1. In Vitro ADME Testing Services Market in Germany, 2019-2030
10.4.2.2. In Vitro ADME Testing Services Market in France, 2019-2030
10.4.2.3. In Vitro ADME Testing Services Market in the UK, 2019-2030
10.4.2.4. In Vitro ADME Testing Services Market in Italy, 2019-2030
10.4.2.5. In Vitro ADME Testing Services Market in Spain, 2019-2030
10.4.2.6. In Vitro ADME Testing Services Market in Rest of Europe, 2019-2030

10.4.3. In Vitro ADME Testing Services Market in Asia-Pacific and Rest of the World, 2019-2030
10.4.3.1. In Vitro ADME Testing Services Market in Japan, 2019-2030
10.4.3.2. In Vitro ADME Testing Services Market in China, 2018-2028
10.4.3.3. In Vitro ADME Testing Services Market in India, 2019-2030
10.4.3.4. In Vitro ADME Testing Services Market in Rest of the World, 2019-2030

10.5. In Vitro ADME Testing Services Market: Distribution by Type of Services, 2019-2030
10.5.1. In Vitro ADME Testing Services Market for Absorption Testing, 2019-2030
10.5.2. In Vitro ADME Testing Services Market for Distribution Testing, 2019-2030
10.5.3. In Vitro ADME Testing Services Market for Metabolism Testing, 2019-2030
10.5.4. In Vitro ADME Testing Services Market for Excretion Testing, 2019-2030

10.6. In Vitro ADME Testing Services Market: Distribution by Type of Assays, 2019-2030
10.6.1. In Vitro ADME Testing Services Market for Caco-2 Permeability Assay, 2019-2030
10.6.2. In Vitro ADME Testing Services Market for Protein Binding Assay, 2019-2030
10.6.3. In Vitro ADME Testing Services Market for Metabolic Stability / Clearance Assay, 2019-2030
10.6.4. In Vitro ADME Testing Services Market for Enzyme Induction Assay, 2019-2030
10.6.5. In Vitro ADME Testing Services Market for Enzyme Inhibition Assay, 2019-2030
10.6.6. In Vitro ADME Testing Services Market for Other Assays, 2019-2030

10.7. In Vitro ADME Testing Services Market: Distribution by Type of Molecules, 2019-2030
10.7.1. In Vitro ADME Testing Services Market for Small Molecules, 2019-2030
10.7.2. In Vitro ADME Testing Services Market for Biologics, 2019-2030

10.8. In Vitro ADME Testing Services Market: Distribution by Therapeutic Areas, 2019-2030
10.8.1. In Vitro ADME Testing Services Market for Blood Disorders, 2019-2030
10.8.2. In Vitro ADME Testing Services Market for Cardiovascular Disorders, 2019-2030
10.8.3. In Vitro ADME Testing Services Market for Gastrointestinal and Digestive Disorders, 2019-2030
10.8.4. In Vitro ADME Testing Services Market for Hormonal Disorders, 2019-2030
10.8.5. In Vitro ADME Testing Services Market for Infectious Diseases, 2019-2030
10.8.6. In Vitro ADME Testing Services Market for Immunological Disorders, 2019-2030
10.8.7. In Vitro ADME Testing Services Market for Mental Disorders, 2019-2030
10.8.8. In Vitro ADME Testing Services Market for Metabolic Disorders, 2019-2030
10.8.9. In Vitro ADME Testing Services Market for Neurological Disorders, 2019-2030
10.8.10. In Vitro ADME Testing Services Market for Cancers, 2019-2030
10.8.11. In Vitro ADME Testing Services Market for Respiratory Disorders, 2019-2030
10.8.12. In Vitro ADME Testing Services Market for Skin Disorders, 2019-2030
10.8.13. In Vitro ADME Testing Services Market for Urogenital Disorders, 2019-2030
10.8.14. In Vitro ADME Testing Services Market for Other Disorders, 2019-2030
10.8.15. In Vitro ADME Testing Services Market: Market Attractiveness Analysis by Therapeutic Areas, 2019-2030

10.9. In Vitro ADME Testing Services Market: Distribution by Type of Sponsors, 2019-2030
10.9.1. In Vitro ADME Testing Services Market for Industry Players, 2019-2030
10.9.2. In Vitro ADME Testing Services Market for Non-Industry Players, 2019-2030

11 CONCLUSION
11.1. In Vitro ADME Studies Conducted During the Early Stages of Drug Development has Demonstrated the Potential to Improve the Probability of Success in Clinical Trials
11.2. Several CROs Offer Services for In Vitro ADME Testing; Most such Companies are based in North America and Europe
11.3. The Market is Dominated by Players having Vast In Vitro ADME Testing Portfolios; Drug Metabolism-related Assays Represent a Major Fraction of Services
11.4. Stakeholders are Actively Expanding their Existing Capabilities to Cater to the Increasing Demand; this is Evident in Number of Acquisitions Reported over the Past Decade
11.5. Owing to the Benefits of Outsourcing, the In Vitro ADME testing Services Market is Expected to Grow at a Healthy Pace in the Foreseen Future

12 EXECUTIVE INSIGHTS
12.1. Chapter Overview
12.2. 490 BioTech
12.2.1. Company Snapshot
12.2.2. Interview Transcript: Dan Close, Chief Scientific Officer

12.3. JRF Global
12.3.1. Company Snapshot
12.3.2. Interview Transcript: Sridhar Iyer, Director and Global Head, Business Development and Sarang Gorte, Assistant Manager, Business Development

13 APPENDIX 1: TABULATED DATA

14 APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List of Figures

Figure 3.1 Drug Discovery and Development Timeline
Figure 3.2 Pharmacokinetics Pathway of a Drug in Human Body
Figure 3.3 Comparison of Oral and Intravascular Drug Administration: Role of Hepatic Portal System
Figure 3.4 Reasons for Attrition in Drug Development
Figure 3.5 ADME Studies in Discovery and Preclinical Development
Figure 3.6 Drivers for In Vitro ADME Testing Studies
Figure 4.1 Guiding Models for Outsourcing
Figure 4.2 Key Characteristics of Transactional Outsourcing Model
Figure 4.3 Key Characteristics of Performance-based Outsourcing Model
Figure 4.4 Key Steps Leading to Outcomes-based Outsourcing Model
Figure 4.5 Factors Influencing Outsourcing Decisions
Figure 4.6 Key Considerations to Select a CRO Partner
Figure 4.7 Role of a CRO in Different Phases of Drug Development
Figure 4.8 End-to-End Integrated Services in Discovery and Preclinical Research
Figure 4.9 Benefits of Outsourcing ADME Testing Services
Figure 4.1 Challenges Related to Outsourcing ADME Testing Services
Figure 5.1 In Vitro ADME Testing Service Providers: Distribution by Year of Establishment
Figure 5.2 In Vitro ADME Testing Service Providers: Distribution by Geographical Location
Figure 5.3 In Vitro ADME Testing Service Providers: Distribution by Year of Establishment and Geography
Figure 5.4 In Vitro ADME Testing Service Providers: Distribution by Company Size
Figure 5.5 In Vitro ADME Testing Service Providers: Distribution by Type of Service Offerings
Figure 5.6 In Vitro ADME Testing Service Providers: Distribution by Type of In Vitro ADME Testing Services
Figure 5.7 In Vitro ADME Testing Service Providers: Distribution by Type of Absorption Assays
Figure 5.8 In Vitro ADME Testing Service Providers: Distribution by Type of Distribution Assays
Figure 5.9 In Vitro ADME Testing Service Providers: Distribution by Type of Metabolism Assays
Figure 5.10 In Vitro ADME Testing Service Providers: Distribution by Type of Molecule
Figure 5.11 In Vitro ADME Testing Service Providers: Distribution by Type of Clientele
Figure 5.12 In Vitro ADME Testing Service Providers Logo Landscape: Distribution by Company Size and Location
Figure 6.1 AMRI: Annual Revenues, 2012-Q1 2017 (USD Million)
Figure 6.2 AMRI: Contract Revenues by Business Segments, 2012-2016 (USD Million)
Figure 6.3 AMRI: In Vitro ADME Testing Service Portfolio
Figure 6.4 Charles River Laboratories: Business Segments
Figure 6.5 Charles River Laboratories: Annual Revenues, 2013-Q3 2018 (USD Billion)
Figure 6.6 Charles River Laboratories: In Vitro ADME Testing Service Portfolio
Figure 6.7 BioDuro: In Vitro ADME Assays Offered
Figure 6.8 RTI International: Annual Revenues, 2013-2017 (USD Million)
Figure 6.9 RTI International: In Vitro ADME Testing Service Portfolio
Figure 6.10 Eurofins Scientific: 2013-Q3 2018 Annual Revenues (EUR Billion)
Figure 6.11 Eurofins Scientific: In Vitro ADME Testing Service Portfolio
Figure 6.12 Evotec: Annual Revenues, 2013–Q1 2018 (EUR Million)
Figure 6.13 Evotec: Revenues by Business Segments, 2017 (EUR Million)
Figure 6.14 Evotec: Drug Discovery Services
Figure 6.15 Galapagos: Annual Revenues, 2013-Q3 2018 (EUR Million)
Figure 6.16 Galapagos: In Vitro ADME Testing Service Portfolio
Figure 6.17 Tecan Group: Annual Revenues, 2013-H1 2018 (CHF Million)
Figure 6.18 Tecan Group: In Vitro ADME Testing Service Portfolio
Figure 6.19 GVK Biosciences: Business Segments
Figure 6.20 GVK Biosciences: In Vitro ADME Testing Service Portfolio
Figure 6.21 Pharmaron: In Vitro ADME Service Portfolio
Figure 6.22 Sai Life Sciences: In Vitro ADME Testing Service Portfolio
Figure 6.23 Shanghai Medicilon: In Vitro ADME Testing Service Portfolio
Figure 6.24 Syngene International: Annual Revenues, 2012–H1 2018 (INR Million)
Figure 6.25 Syngene International: In Vitro ADME Testing Service Portfolio
Figure 6.26 WuXi AppTec: Annual Revenues, 2011-9M 2015 (USD Million)
Figure 6.27 WuXi AppTec: In Vitro ADME Testing Service Portfolio
Figure 7.1 Benchmark Analysis: Distribution of Companies by Geographical Location and Company Size
Figure 7.2 Benchmark Analysis: Peer Group I
Figure 7.3 Benchmark Analysis: Peer Group II
Figure 7.4 Benchmark Analysis: Peer Group III
Figure 7.5 Benchmark Analysis: Peer Group IV
Figure 7.6 Benchmark Analysis: Peer Group V
Figure 7.7 Benchmark Analysis: Peer Group VI
Figure 7.8 Benchmark Analysis: Peer Group VII
Figure 7.9 Benchmark Analysis: Peer Group VIII
Figure 7.10 Benchmark Analysis: Comparison Across Peer Groups
Figure 8.1 Acquisitions: Year-Wise Cumulative Trend (2005-2018)
Figure 8.2 Acquisitions: Regional Distribution
Figure 8.3 Acquisitions: Intercontinental and Intracontinental Acquisitions
Figure 8.4 Acquisitions: Ownership Change Matrix
Figure 8.5 Acquisitions: Most Active Acquirers
Figure 8.6 Acquisitions: Key Value Drivers
Figure 8.7 Acquisitions: Heat Map Analysis by Key Value Drivers and Year of Acquisition
Figure 9.1 Regulatory Guidelines for Non-Clinical Studies
Figure 9.2 ICH: Regulatory and Industry Participants
Figure 9.3 ICH: Guidance Documents for Non-Clinical Studies
Figure 9.4 USFDA: GLP Guidelines for Non-Clinical Studies
Figure 9.5 Regulatory Landscape for In Vitro ADME Testing Service Providers: Analysis by Type of Regulatory Authorities
Figure 10.1 Overall In Vitro ADME Testing Services Market, 2019-2030: Base Scenario (USD Billion)
Figure 10.2 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Regions, Base Scenario (USD Billion)
Figure 10.3 In Vitro ADME Testing Services Market: Share by Regions, 2019 and 2030
Figure 10.4 In Vitro ADME Testing Services Market, 2019-2030: North America, Base Scenario (USD Billion)
Figure 10.5 In Vitro ADME Testing Services Market, 2019-2030: US, Base Scenario (USD Million)
Figure 10.6 In Vitro ADME Testing Services Market, 2019-2030: Canada, Base Scenario (USD Million)
Figure 10.7 In Vitro ADME Testing Services Market, 2019-2030: Europe, Base Scenario (USD Billion)
Figure 10.8 In Vitro ADME Testing Services Market, 2019-2030: Germany, Base Scenario (USD Million)
Figure 10.9 In Vitro ADME Testing Services Market, 2019-2030: France, Base Scenario (USD Million)
Figure 10.10 In Vitro ADME Testing Services Market, 2019-2030: UK, Base Scenario (USD Million)
Figure 10.11 In Vitro ADME Testing Services Market, 2019-2030: Italy, Base Scenario (USD Million)
Figure 10.12 In Vitro ADME Testing Services Market, 2019-2030: Spain, Base Scenario (USD Million)
Figure 10.13 In Vitro ADME Testing Services Market, 2019-2030: Rest of Europe, Base Scenario (USD Million)
Figure 10.14 In Vitro ADME Testing Services Market, 2019-2030: Asia-Pacific and Rest of the World, Base Scenario (USD Billion)
Figure 10.15 In Vitro ADME Testing Services Market, 2019-2030: Japan, Base Scenario (USD Million)
Figure 10.16 In Vitro ADME Testing Services Market, 2019-2030: China, Base Scenario (USD Million)
Figure 10.17 In Vitro ADME Testing Services Market, 2019-2030: India, Base Scenario (USD Million)
Figure 10.18 In Vitro ADME Testing Services Market, 2019-2030: Rest of the World, Base Scenario (USD Million)
Figure 10.19 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Services, Base Scenario (USD Million)
Figure 10.20 In Vitro ADME Testing Services Market: Share by Type of Services, 2019 and 2030
Figure 10.21 In Vitro ADME Testing Services Market for Absorption Testing, 2019-2030: Base Scenario (USD Million)
Figure 10.22 In Vitro ADME Testing Services Market for Distribution Testing, 2019-2030: Base Scenario (USD Million)
Figure 10.23 In Vitro ADME Testing Services Market for Metabolism Testing, 2019-2030: Base Scenario (USD Million)
Figure 10.24 In Vitro ADME Testing Services Market for Excretion Testing, 2019-2030: Base Scenario (USD Million)
Figure 10.25 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Assays, Base Scenario (USD Million)
Figure 10.26 In Vitro ADME Testing Services Market: Share by Type of Assays, 2019 and 2030
Figure 10.27 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Caco-2 Permeability Assay, Base Scenario (USD Million)
Figure 10.28 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Protein Binding Assay, Base Scenario (USD Million)
Figure 10.29 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Metabolic Stability / Clearance Assay, Base Scenario (USD Million)
Figure 10.30 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Enzyme Induction Assay, Base Scenario (USD Million)
Figure 10.31 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Enzyme Inhibition Assay, Base Scenario (USD Million)
Figure 10.32 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Other Assays, Base Scenario (USD Million)
Figure 10.33 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Molecules, Base Scenario (USD Billion)
Figure 10.34 In Vitro ADME Testing Services Market: Share by Type of Molecules, 2019 and 2030
Figure 10.35 In Vitro ADME Testing Services Market for Small Molecules, 2019-2030: Base Scenario (USD Billion)
Figure 10.36 In Vitro ADME Testing Services Market for Biologics, 2019-2030: Base Scenario (USD Billion)
Figure 10.37 In Vitro ADME Testing Services Market for Blood Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.38 In Vitro ADME Testing Services Market for Cardiovascular Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.39 In Vitro ADME Testing Services Market for Gastrointestinal and Digestive Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.40 In Vitro ADME Testing Services Market for Hormonal Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.41 In Vitro ADME Testing Services Market for Infectious Diseases, 2019-2030: Base Scenario (USD Million)
Figure 10.42 In Vitro ADME Testing Services Market for Immunological Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.43 In Vitro ADME Testing Services Market for Mental Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.44 In Vitro ADME Testing Services Market for Metabolic Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.45 In Vitro ADME Testing Services Market for Neurological Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.46 In Vitro ADME Testing Services Market for Cancers, 2019-2030: Base Scenario (USD Million)
Figure 10.47 In Vitro ADME Testing Services Market for Respiratory Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.48 In Vitro ADME Testing Services Market for Skin Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.49 In Vitro ADME Testing Services Market for Urogenital Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.50 In Vitro ADME Testing Services Market for Other Disorders, 2019-2030: Base Scenario (USD Million)
Figure 10.51 In Vitro ADME Testing Services Market, 2019-2030: Market Attractiveness by Therapeutic Areas, Base Scenario (USD Million)
Figure 10.52 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Sponsors, Base Scenario (USD Billion)
Figure 10.53 In Vitro ADME Testing Services Market: Share by Type of Sponsors, 2019 and 2030
Figure 10.54 In Vitro ADME Testing Services Market for Industry Players, 2019-2030: Base Scenario (USD Billion)
Figure 10.55 In Vitro ADME Testing Services Market for Non-Industry Players, 2019-2030: Base Scenario (USD Billion)
Figure 11.1 Overall In Vitro ADME Testing Services Market, Conservative, Base and Optimistic Scenarios, 2019, 2024 and 2030 (USD Billion)

List of Tables

Table 3.1 List of Assays Performed During ADME Studies
Table 5.1 In Vitro ADME Testing Services: List of Industry Players
Table 5.2 In Vitro ADME Testing Service Providers: Information on Type of In Vitro ADME Testing Services
Table 5.3 In Vitro ADME Testing Service Providers: Information on Type of Molecule
Table 5.4 In Vitro ADME Testing Service Providers: Information on Type of Clientele
Table 5.5 In Silico ADME Testing Services: List of Industry Players
Table 6.1 In Vitro ADME Testing Services: List of Companies Profiled
Table 6.2 AMRI: Key Highlights
Table 6.3 AMRI: Recent / Past Trends and Future Outlook
Table 6.4 Charles River Laboratories: Key Highlights
Table 6.5 Charles River Laboratories: Recent / Past Trends and Future Outlook
Table 6.6 BioDuro: Key Highlights
Table 6.7 BioDuro: Recent / Past Trends and Future Outlook
Table 6.8 RTI International: Key Highlights
Table 6.9 RTI International: Recent / Past Trends and Future Outlook
Table 6.10 Eurofins Scientific: Key Highlights
Table 6.11 Eurofins Scientific: Recent / Past Trends and Future Outlook
Table 6.12 Evotec: Key Highlights
Table 6.13 Evotec: In Vitro ADME Assays Offered
Table 6.14 Evotec: Recent / Past Trends and Future Outlook
Table 6.15 Galapagos: Key Highlights
Table 6.16 Galapagos: Recent / Past Trends and Future Outlook
Table 6.17 Tecan Group: Key Highlights
Table 6.18 Tecan Group: Recent / Past Trends and Future Outlook
Table 6.19 GVK Biosciences: Key Highlights
Table 6.20 GVK Biosciences: Recent / Past Trends and Future Outlook
Table 6.21 Pharmaron: Key Highlights
Table 6.22 Pharmaron: Recent / Past Trends and Future Outlook
Table 6.23 Sai Life Sciences: Key Highlights
Table 6.24 Sai Life Sciences: Recent / Past Trends and Future Outlook
Table 6.25 Shanghai Medicilon: Key Highlights
Table 6.26 Shanghai Medicilon: Recent / Past Trends and Future Outlook
Table 6.27 Syngene International: Key Highlights
Table 6.28 Syngene International: Recent / Past Trends and Future Outlook
Table 6.29 WuXi AppTec: Key Highlights
Table 6.30 WuXi AppTec: Recent / Past Trends and Future Outlook
Table 7.1 Benchmark Analysis: Peer Groups
Table 8.1 In Vitro ADME Testing Services: Mergers and Acquisitions
Table 8.2 In Vitro ADME Testing Services: Information on Key Value Drivers of Acquisitions
Table 8.3 Key Acquisitions: Deal Multiples
Table 9.1 USFDA: Guidance Documents for Non-Clinical Studies
Table 9.2 EMA: Guidance Documents for Non-Clinical Studies
Table 9.3 MHLW: Guidance Documents for Non-Clinical Studies
Table 9.4 In Vitro ADME Testing Service Providers: Information on Regulatory Approval
Table 12.1 490 BioTech: Key Highlights
Table 12.2 JRF Global: Key Highlights
Table 13.1 Reasons for Attrition in Drug Development
Table 13.2 In Vitro ADME Testing Service Providers: Distribution by Year of Establishment
Table 13.3 In Vitro ADME Testing Service Providers: Distribution by Geographical Location
Table 13.4 In Vitro ADME Testing Service Providers: Distribution by Year of Establishment and Geography
Table 13.5 In Vitro ADME Testing Service Providers: Distribution by Company Size
Table 13.6 In Vitro ADME Testing Service Providers: Distribution by Type of Service Offerings
Table 13.7 In Vitro ADME Testing Service Providers: Distribution by Type of In Vitro ADME Testing Services
Table 13.8 In Vitro ADME Testing Service Providers: Distribution by Type of Absorption Assays
Table 13.9 In Vitro ADME Testing Service Providers: Distribution by Type of Distribution Assays
Table 13.10 In Vitro ADME Testing Service Providers: Distribution by Type of Metabolism Assays
Table 13.11 In Vitro ADME Testing Service Providers: Distribution by Type of Molecule
Table 13.12 In Vitro ADME Testing Service Providers: Distribution by Type of Clientele
Table 13.13 AMRI: Annual Revenues, 2012-Q1 2017 (USD Million)
Table 13.14 AMRI: Contract Revenues by Business Segments, 2012-2016 (USD Million)
Table 13.15 Charles River Laboratories: Annual Revenues, 2013-Q3 2018 (USD Billion)
Table 13.16 RTI International: Annual Revenues, 2013-2017 (USD Million)
Table 13.17 Eurofins Scientific: 2013-Q3 2018 Annual Revenues (EUR Billion)
Table 13.18 Evotec: Annual Revenues, 2013–Q1 2018 (EUR Million)
Table 13.19 Evotec: Revenues by Business Segments, 2017 (EUR Million)
Table 13.20 Galapagos: Annual Revenues, 2013-Q3 2018 (EUR Million)
Table 13.21 Tecan Group: Annual Revenues, 2013-H1 2018 (CHF Million)
Table 13.22 Syngene International: Annual Revenues, 2012–H1 2018 (INR Million)
Table 13.23 WuXi AppTec: Annual Revenues, 2011-9M 2015 (USD Million)
Table 13.24 Benchmark Analysis: Distribution of Companies by Geographical Location and Company Size
Table 13.25 Benchmark Analysis: Peer Group I
Table 13.26 Benchmark Analysis: Peer Group II
Table 13.27 Benchmark Analysis: Peer Group III
Table 13.28 Benchmark Analysis: Peer Group IV
Table 13.29 Benchmark Analysis: Peer Group V
Table 13.30 Benchmark Analysis: Peer Group VI
Table 13.31 Benchmark Analysis: Peer Group VII
Table 13.32 Benchmark Analysis: Peer Group VIII
Table 13.33 Acquisitions: Year-Wise Cumulative Trend (2005-2018)
Table 13.34 Acquisitions: Regional Distribution
Table 13.35 Acquisitions: Intercontinental and Intracontinental Acquisitions
Table 13.36 Acquisitions: Ownership Change Matrix
Table 13.37 Acquisitions: Most Active Acquirers
Table 13.38 Acquisitions: Key Value Drivers
Table 13.39 Acquisitions: Heat Map Analysis by Key Value Drivers and Year of Acquisition
Table 13.40 Regulatory Landscape for In Vitro ADME Testing Service Providers: Analysis by Type of Regulatory Authorities
Table 13.41 Overall In Vitro ADME Testing Services Market, 2019-2030: Conservative Scenario (USD Billion)
Table 13.42 Overall In Vitro ADME Testing Services Market, 2019-2030: Base Scenario (USD Billion)
Table 13.43 Overall In Vitro ADME Testing Services Market, 2019-2030: Optimistic Scenario (USD Billion)
Table 13.44 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Regions, Conservative Scenario (USD Billion)
Table 13.45 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Regions, Base Scenario (USD Billion)
Table 13.46 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Regions, Optimistic Scenario (USD Billion)
Table 13.47 In Vitro ADME Testing Services Market, 2019-2030: North America, Conservative Scenario (USD Million)
Table 13.48 In Vitro ADME Testing Services Market, 2019-2030: North America, Base Scenario (USD Million)
Table 13.49 In Vitro ADME Testing Services Market, 2019-2030: North America, Optimistic Scenario (USD Million)
Table 13.50 In Vitro ADME Testing Services Market, 2019-2030: Europe, Conservative Scenario (USD Million)
Table 13.51 In Vitro ADME Testing Services Market, 2019-2030: Europe, Base Scenario (USD Million)
Table 13.52 In Vitro ADME Testing Services Market, 2019-2030: Europe, Optimistic Scenario (USD Million)
Table 13.53 In Vitro ADME Testing Services Market, 2019-2030: Asia-Pacific and Rest of the World, Conservative Scenario (USD Million)
Table 13.54 In Vitro ADME Testing Services Market, 2019-2030: Asia-Pacific and Rest of the World, Base Scenario (USD Million)
Table 13.55 In Vitro ADME Testing Services Market, 2019-2030: Asia-Pacific and Rest of the World, Optimistic Scenario (USD Million)
Table 13.56 In Vitro ADME Testing Services Market: Share by Regions, 2019 and 2030
Table 13.57 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Services, Conservative Scenario (USD Million)
Table 13.58 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Services, Base Scenario (USD Million)
Table 13.59 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Services, Optimistic Scenario (USD Million)
Table 13.60 In Vitro ADME Testing Services Market: Share by Type of Services, 2019 and 2030
Table 13.61 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Assays, Conservative Scenario (USD Million)
Table 13.62 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Assays, Base Scenario (USD Million)
Table 13.63 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Assays, Optimistic Scenario (USD Million)
Table 13.64 In Vitro ADME Testing Services Market: Share by Type of Assays, 2019 and 2030
Table 13.65 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Molecules, Conservative Scenario (USD Billion)
Table 13.66 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Molecules, Base Scenario (USD Billion)
Table 13.67 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Molecules, Optimistic Scenario (USD Billion)
Table 13.68 In Vitro ADME Testing Services Market: Share by Type of Molecules, 2019 and 2030
Table 13.69 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Therapeutic Areas, Conservative Scenario (USD Million)
Table 13.70 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Therapeutic Areas, Base Scenario (USD Million)
Table 13.71 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Therapeutic Areas, Optimistic Scenario (USD Million)
Table 13.72 In Vitro ADME Testing Services Market, 2019-2030: Market Attractiveness Analysis by Therapeutic Areas (USD Million)
Table 13.73 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Sponsors, Conservative Scenario (USD Billion)
Table 13.74 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Sponsors, Base Scenario (USD Billion)
Table 13.75 In Vitro ADME Testing Services Market, 2019-2030: Distribution by Type of Sponsors, Optimistic Scenario (USD Billion)
Table 13.76 In Vitro ADME Testing Services Market: Share by Type of Sponsors, 2019 and 2030

List of Companies

Please reach out to our team for the details.