Autoinjectors Innovation Landscape

Autoinjectors: Intellectual Property Landscape, Featuring Historical and Contemporary Patent Filing Trends, Prior Art Search Expressions, Patent Valuation Analysis, Patentability, Freedom to Operate, Pockets of Innovation, Existing White Spaces, and Claims Analysis

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Report Description

According to the National Health Council, nearly 40% of the adult population in the US is diagnosed with at least one chronic condition, such as diabetes, asthma, and hypertension. The annual cost burden associated with chronic diseases in the US is around USD 3.8 trillion. A major share of expenses incurred by patients living with a chronic disorder is driven by the frequent need to medicate, which may require repeated visits to hospitals / out-patient clinics. This has prompted stakeholders to develop devices that enable self-administration of drugs. Amongst the various self-injection devices, autoinjectors have steadily gained prominence, especially for the treatment of emergency and chronic conditions. However, there are several challenges associated with such devices, such as safety issues, human errors and dosing errors.

In order to overcome the aforementioned challenges, players are engaged in the development of cutting-edge technology, such as feedback systems in autoinjectors that track the injection process of therapies. Presently, close to 80 autoinjectors are available in the market, of which nearly 40% are accessible in combination with therapeutics and have disposable components. In addition, a significant increase in the research and development efforts for reusable autoinjectors has been observed. This can be attributed to the fact that the development of reusable or multi chambered autoinjectors is likely to reduce the cost of therapy for patients. It is worth mentioning that more than 11,000 patents have been filed / granted by the stakeholders related to autoinjectors. As a result, the intellectual capital around reusable components, reusable autoinjectors and associated methods of use has also grown, indicating the cost saving potential of the autoinjectors. Given these trends, it is crucial to monitor both the pockets of creativity and the white spaces that signal areas with a high potential for innovation. This report captures some of the key R&D-related trends and provides competitive intelligence on intellectual property in the field of autoinjectors.

Scope of the Report

The “Autoinjectors: Intellectual Property Landscape” report features an extensive study of some of the key historical and contemporary intellectual property (IP) documents (featuring granted patents, patent applications and other documents), describing the various types of autoinjectors and their components intended to offer safety features and patient compliance during self-administration of drugs. The insights generated in this report have been presented across two deliverables, namely a MS Excel workbook and a MS PowerPoint deck, summarizing the ongoing activity in this domain. Key inclusions are briefly described below:

  • Overall Intellectual Property Landscape
    An analytical perspective of the various patents and affiliated IP documents that have been published related to autoinjectors, since 1973. An in-depth analysis of published IP documents, representing unique patent families across various global jurisdictions, featuring insightful inferences related to both historical and recent R&D trends within this niche, but rapidly evolving segment of the biopharmaceutical industry.
  • Popular / Relevant Prior Art Search Expressions
    An examination of IP literature, shortlisting key words and phrases used to describe autoinjectors (and affiliated products) that are either already available in the market, or under development. The analysis also includes details on the historical use of the aforementioned terms across different IP filings, key affiliated terms (which can be used to identify other relevant IP search terms and establish relationships between prior art search expressions), and other related trends.
  • Patent Valuation Analysis
    A competitive benchmarking and valuation analysis of the key members of unique patent families captured in the report, taking into consideration important parameters, such as type of IP document, year of application, time to expiry, number of citations and jurisdiction (factoring in value associated with the gross domestic product (GDP) of a particular region).
  • Patentability and Freedom to Operate
    A systematic approach to identifying relevant areas of innovation by analyzing published IP documents (representative of unique patent families), by defining the uniqueness of patented / patent pending innovations, in order to assess the scope of patentability in this domain, and pinpoint jurisdictions wherein new and / or modified claims may be filed without infringing on existing IP. 
  • Analysis of Patent Applications
    A detailed summary of the various patent applications (representative of unique patent families) that were filed across different jurisdictions and their relative value in the IP ecosystem. The analysis classified the intellectual capital in terms of innovation and type of innovation (such as a product class, enabling technologies or method of use), thereby, offering the means to identify active arenas of research and assess innovation-specific IP filing trends.
  • Analysis of Granted Patents
    An analysis of the granted patents (representative of unique patent families) across different global jurisdictions and their relative value in the IP ecosystem. The analysis also features a meaningful classification system, segregating granted IP into relevant categories (namely type of innovation and innovation) to help develop a detailed perspective on the diversity of intellectual capital (having marketing exclusivity) related to autoinjectors, and the assessing likelihood for innovators to enter into promising research areas.
  • Pockets of Innovation and White Spaces
    An insightful analysis of the various CPC codes used in published IP literature (representative of unique patent families) and their affiliated families, offering the means to identify historical and existing pockets of innovation (based on the functional area / industry described by the elaborate and systematic IP classification approach, mentioned earlier); the analysis also features a discussion on prevalent white spaces (based on innovation and type of innovation) in this field of research.
  • Claim Analysis
    One of the objectives of the report was to analyze and summarize key inferences from the independent claims mentioned in granted, active patents (representative of unique patent families) in the dataset. Using a systematic segregation approach, we have analyzed trends associated with the preamble, type of patent (product patent or method patent), type of claim (open ended claim or closed ended claim) and key elements of a claim (individual aspects of an innovation that are covered in a singular claim).

Contents

DELIVERABLE OUTLINES

Excel Deliverable

Sheet 1 features details regarding how the input data for this project was collated, including the search strings used to query a popular, public patent database (namely lens.org), and data segregation notes. 

Sheet 2 is a summary MS Excel dashboard, offering a detailed, graphical perspective of the intellectual property landscape of autoinjectors. It includes pictorial representations of the overall patent landscape, IP documents representing patent families that describe unique innovations related to autoinjectors, trends related to patent applications (including insights on patentability and freedom to operate), trends related to granted patents (including insights on patentability and freedom to operate), key inferences from a proprietary claims analysis, list of popular CPC symbols (featuring key pockets of innovation), list of popular applicants (shortlisted based on number of published IP documents), and list of non-English patents (including IP documents with undecipherable language and script as downloaded from lens.org)
    
Sheet 3 is an elaborate tabular representation of the overall IP landscape, featuring information on the various types of IP documents, related to autoinjectors, which have been published since 1973. 

Sheet 4 is an excerpt of the data presented in the previous sheet, featuring published IP documents, that represent unique patent families across various global jurisdictions. This dataset has been analyzed in detail, in the report. 

Sheet 5 includes a tabular representation of the key words and phrases (prior art search expressions) that are used to describe autoinjectors and affiliated intellectual capital.

Sheet 6 is a subset of sheet 4, featuring all the patent applications, covering innovations related to autoinjectors and affiliated methods / products.

Sheet 7 is a subset of sheet 4, featuring all the granted patents, covering innovations related to autoinjectors and affiliated methods / products. 

Sheet 8 is an insightful summary of key inferences from the independent claims of the granted, active patents in the dataset. It involves the use of a systematic segregation approach to analyze key trends associated with the preamble, type of patent (product patent or method patent), type of claim (open ended claim or closed ended claim) and key elements of a claim (individual aspects of an innovation that are covered in a singular claim).

Sheet 9 provides insights related to some of the key applicants that are active in this field of research, featuring company-specific details (such as year of establishment, and location of headquarters), and inputs on their respective IP publication trends. 
    
Sheet 10 features an analysis of the most popular CPC symbols and CPC families (in terms of frequency of appearance in the dataset), related to autoinjectors that are either already available in the market, or under development. 

Sheet 11 is a subset of Sheet 4 and features a list of IP documents with non-English patent literature, with the contents of the documents filed in the native language of the applicants’ country and have not been analyzed in the research report.

Sheet 12 is an appendix, which includes pivot tables that drive the charts and interactive elements for the complete IP landscape depicted in sheet 2 of the deliverable.

Sheet 13 is an appendix, featuring details related to the categorization done in the report, and important abbreviations used in reference to the data categories mentioned in the document. 

PowerPoint Deliverable
Chapter 1 briefly describes of the need for autoinjectors interventions, and the key advantages associated with the use of such devices. Further, it provides an overview of the intellectual property landscape related to this important yet relatively less explored domain of autoinjectors. 

Chapter 2 and 3 feature brief (pictorial) summaries of the approach used during data collection for this project, and the key objectives of the study.

Chapter 4 is an executive summary of the important insights and key takeaways, generated from analyzing the IP landscape of autoinjectors.

Chapter 5 offers an informed perspective on the core concepts of autoinjectors. It also includes brief descriptions of autoinjectors and important milestones in this field of research, highlighting some of the important breakthrough approvals in the field of autoinjectors. Further, it provides a summary of the important application areas, advantages and existing limitations of autoinjectors. Finally, the chapter also features a discussion on recent developments, providing an informed future outlook backed by informed opinions and insights from several key senior stakeholders in the industry.

Chapter 6 includes a review of the various patents and affiliated IP documents that have been published related to autoinjectors, since the year 1973. It also features an in-depth analysis of published IP documents, representing unique patent families across various global jurisdictions, and includes insightful inferences related to both historical and recent R&D trends within this niche, but rapidly evolving segment of the biopharmaceutical industry.

Chapter 7 features an insightful examination of IP literature, highlighting key words and phrases that are used to describe different autoinjectors, including information on historical usage in IP filings, key affiliated terms (which can be used to identify other relevant IP search terms and establish relationships between prior art search expressions), and other related trends.

Chapter 8 offers insights from a competitive benchmarking and valuation analysis of the key members of unique patent families that have been captured in the report. It takes into consideration important parameters, such as type of IP document, year of application, time to expiry, number of citations and jurisdiction (factoring in value associated with the gross domestic product (GDP) of a particular region).

Chapter 9 provides a detailed summary of the patent applications (representative of unique patent families) that were filed across different jurisdictions and their relative value in the IP ecosystem. The analysis segregates the captured intellectual capital in terms of type of innovation and the specific innovation (novel products, enabling technologies or methods of use), thereby, offering the means to identify active arenas of research and assess innovation-specific IP filing trends. Further, it features an analysis that helps identify relevant areas of innovation by analyzing published IP documents (representative of unique patent families), defining the uniqueness of patent pending innovations, in order to assess the scope of patentability in this domain, and pinpoint jurisdictions where new and / or modified claims may be filed without infringing on existing IP.

Chapter 10 is an elaborate summary of the granted patents (representative of unique patent families) across different global jurisdictions and their relative value in the IP ecosystem. The analysis also features a meaningful classification system, segregating granted IP into relevant categories (namely type of innovation and innovation) to help develop a detailed perspective on the diversity of intellectual capital (having marketing exclusivity) related to autoinjectors, and the assessing likelihood for innovators to enter into promising product markets, once active patents expire. Further, it features an analysis that helps identify relevant areas of innovation by analyzing published IP documents (representative of unique patent families), defining the uniqueness of patented innovations, in order to assess the scope of patentability in this domain, and pinpoint jurisdictions where new and / or modified claims may be filed without infringing on existing IP.

Chapter 11 features profiles of some of the most popular applicant companies, which were shortlisted based on their respective patent filing activities. Each profiles includes a brief overview of the company, information on annual revenues (wherever available), details of its autoinjector portfolio, names of key management team members and recent developments. 

Chapter 12 includes an insightful analysis of the various CPC symbols mentioned in published IP literature (representative of unique patent families) and their affiliated families, offering the means to identify historical and existing pockets of innovation (based on the functional area / industry described by the elaborate and systematic IP classification approach, mentioned earlier); the analysis also features a discussion on prevalent white spaces (based on innovation and type of innovation) in this field of research.

Chapter 13 concludes the report by summarizing publicly available insights on the anticipated developments in this domain (taking into consideration the perspectives of eminent representatives of stakeholder companies in this industry), and trends that are likely to shape the future of autoinjectors.

Chapter 14 is a set of appendices, entailing an overview of the excel research report, a list of IP documents featuring the identified white spaces, table of contents, list of figures, list of tables, glossary, and list of all the applicant companies and organizations.

Table Of Contents

Excel Deliverable

1. Research Notes

2. Summary Dashboard
A. Overall Intellectual Property Landscape
B. Intellectual Property Landscape (Grouped by Simple Families)
C. Key Prior Art Search Expressions
D. Key Trends related to Patent Applications (featuring Patentability and Freedom-to-Operate)
E. Key Trends related to Granted Patents (featuring Patentability and Freedom-to-Operate)
F. Claim Analysis
G. Key CPC Symbols
H. Key Applicants

3. Overall Intellectual Property Landscape Dataset

4. Prior Art Search Expressions (Keyword Analysis)

5. Patent Applications Dataset

6. Granted Patents Dataset

7. Claim Analysis

8. Key Applicants Analysis

9. CPC Analysis

10. Appendix I: Pivot Tables

11. Appendix II: Country / Geography Codes

12. Appendix III: Innovation Categories

PowerPoint Deliverable 
1. Context

2. Project Approach

3. Project Objectives

4. Executive Summary

5. Introduction
5.1. Overview
5.2. Limitations of Conventional Methods
5.3. Need of Self Administrations
5.4. Autoinjectors
5.5. Classification of Autoinjectors
5.6. Benefits of Autoinjectors

6. Overall Intellectual Property Landscape
6.1. Overview
6.2. Analysis of Simple Patent Families
6.3. Key Innovation Categories
6.4. Insights from Patent Applications
6.5. Insights from Granted Patents

7. Key Prior Art Search Expressions
7.1. Overview
7.2. Analysis of Prior Art Search Expressions

8. Intellectual Property Valuation Analysis
8.1. Valuation Overview
8.2. Analysis of Individual Value Ranks
8.2.1. Rank 1 IP Documents
8.2.2. Rank 2 IP Documents
8.2.3. Rank 3 IP Documents
8.2.4. Rank 4 IP Documents
8.2.5. Rank 5 IP Documents
8.3. Concluding Remarks
8.4. List of Rank 1 IP Documents

9. Analysis of Patent Applications
9.1. Overview
9.2. Relative Valuation of Patent Applications
9.3. Patentability & Freedom-to-Operate

10. Analysis of Granted Patents
10.1. Overview
10.2. Relative Valuation of Grated Patents
10.3. Patentability & Freedom-to-Operate
10.4. Analysis of Patent Claims (Granted Active Patents)

11. Key Applicants
11.1. Overview
11.2. Analysis of Key Applicants
11.2.1. Company A
11.2.2. Company B
11.2.3. Company C
11.2.4. Company D
11.2.5. Company E
11.2.6. Company F
11.2.7. Company G
11.2.8. Company H
11.2.9. Company I
11.2.10. Company J

12. Pockets of Innovation and White Spaces
12.1. Overview
12.2. Pockets of Innovation
12.3. White Spaces
12.4. Concluding Remarks

13. Future Outlook
13.1. Overview
13.2. Contemporary Sentiments & Expert Opinions
13.3. Future Perspectives

14. Appendices

List Of Companies

The following companies / institutes / government bodies and organizations have been mentioned in this report:

  1. Abbott Laboratories
  2. AbbVie
  3. Above The Fold
  4. Adar MedTech
  5. AdrenaCard
  6. Aguettant
  7. Aijex Pharma
  8. Air Force Medical University
  9. Aktiv Pharma Group
  10. Alcon
  11. Alcyone Therapeutics
  12. ALICE 123
  13. ALK-Abelló
  14. Allergan (acquired by AbbVie)
  15. Alza
  16. Amgen
  17. Amorepacific
  18. AngioDynamics
  19. Anhui Hongyu Wuzhou Medical Manufacturer
  20. Anhui Yuandong Biological Technology
  21. Ansan College of Technology
  22. Antares Pharma
  23. APS Injector
  24. Aptar
  25. Ares Trading
  26. Arrow Medical 
  27. Asahi Kasei Pharma
  28. Ascendis Pharma
  29. Astra Meditech
  30. Autoject Systems
  31. Avant
  32. B. Braun Melsungen
  33. Bang & Olufsen Medicom
  34. Banza Stamping Industry
  35. Battelle Memorial Institute
  36. Bayer
  37. Becton Dickinson
  38. Beijing Institute of Nanoenergy and Nanosystems
  39. Beijing Runmei Yuzhiguang Medical Beauty
  40. Beijing Tianneng Sunny Science & Technology 
  41. Beijing Yangshi Haohua Technology And Trade 
  42. Beilun People's Hospital
  43. Benchmark Internet Group 
  44. Berpu Medical Technology
  45. Berry Global
  46. Bespack (acquired by Resipharm)
  47. Biocon
  48. Biocorp
  49. Biocorp Production
  50. BioFront Technologies
  51. Biogen
  52. Bioject Medical Technologies
  53. Bioworld Technology
  54. Birya Biotech
  55. Blue Lead Medical
  56. Boehringer Ingelheim
  57. Bristol-Myers Squibb
  58. Brovedani
  59. California Institute of Technology
  60. Cambridge Biostability
  61. Cambridge Consultants
  62. Camurus
  63. Carebay Europe
  64. CC Biotech
  65. CCBio
  66. Changhai Hospital
  67. Changzhou Kangxin Medical Instruments
  68. Chemprotect
  69. Chengdu Antejin Biotech 
  70. Chengdu Kechuang Jiasi Technology
  71. Chengdu TCWY New Energy Technology
  72. Chinese Metering University
  73. Chongqing Haodeyi Information Technology
  74. Chongqing Zhongdian Dayu Satellite Application Tech Institute
  75. Chungbuk National University
  76. Chungjin Biotech
  77. Cilag
  78. Cincinnati Children's Hospital Medical Center
  79. Clearside Biomedical
  80. ConnectMeSmart
  81. Consort Medical
  82. Copernicus
  83. Creare
  84. Crossject
  85. Daewoong Pharmaceutical
  86. Daicel
  87. Dankook University
  88. DCA Design International
  89. Difinity Solutions
  90. DJ Medical
  91. DNK Technologies
  92. Dongguan Jinyue Electronic Technology
  93. Dr Reddy’s Laboratories
  94. Drone Delivery Canada 
  95. Duoject Medical Systems
  96. Duphar International Research
  97. E.L.M. Plastic
  98. E3D Agricultural Cooperative Association
  99. E3D Elcam Drug Delivery Devices
  100. Ebbvi Bajoteknolodzhi Ltd
  101. Elan Pharma International
  102. Elcam Medical Agricultural Cooperative Association
  103. Emergent Product Development Gaithersburg
  104. Emperra E-Health Technologies
  105. Enable Injections
  106. EOFLOW
  107. Epson
  108. Equidyne Systems
  109. Eunsung Global
  110. EVEON
  111. E-WHA Meditech
  112. Falcon Medical
  113. Feldreich Caro Ruiz
  114. Felton International
  115. Fi-Tek
  116. Flextronics
  117. Foshan University
  118. Foshan Yaboli Technology
  119. FPIN (Family Physicians Inquiries Network)
  120. Future Injection Technology
  121. Fuzhou Lian Qi Intelligent Technology
  122. GadLight
  123. Gan & Lee Pharmaceuticals
  124. Gansu ChanGee Bio-Pharmaceutical 
  125. Genentech
  126. Genesis MedTech
  127. Gifthealth
  128. GlaxoSmithKline
  129. Gold NanoTech
  130. GTG Wellness
  131. Guangdong Provincial People's Hospital 
  132. H&B Electronic
  133. Hangzhou Lanbishi Trade 
  134. Hangzhou MED Technology
  135. Haselmeier
  136. Haselmeier (A part of Medmix)
  137. Health Ricerca E Sviluppo
  138. Healthcare Triangle
  139. Henan Hengfei Biological Technology
  140. Henke Sass Wolf 
  141. Henry Schein
  142. HIOS
  143. Hoffman La Roche
  144. Hospira (A part of Pfizer)
  145. Huayang Electrical Appliance
  146. Huazhong University of Science and Technology
  147. HuBioMed
  148. Huizhou Minglong Technology 
  149. Human & Biz
  150. Humboldt Solutions
  151. Hunan Xialong Medical Instrument Manufacturing
  152. Huzhou University
  153. Inject Pharma
  154. IntelliJect
  155. Intervet International
  156. Invivotek
  157. Jabil Healthcare
  158. Janssen Pharmaceuticals (Acquired by Johnson & Johnson)
  159. Jeisys Medical
  160. Jiading District Central Hospital 
  161. Jiamusi University
  162. Jiangsu Delfu Medical Device
  163. Jiangxi Agricultural University
  164. Jiangxi Yikang Medical Instrument
  165. Jiangxi Zhengbang Technology 
  166. Johnson & Johnson
  167. JSK Biomed
  168. Juvaplus
  169. Kailian Medical
  170. Kaléo
  171. Ki. Works Vietnam
  172. Korea Institute of Industrial Technology
  173. Krontek Farma
  174. Kunming Pharmaceutical
  175. Kyungpook National University
  176. L + N - Plast - Vertrieb
  177. Leopard Green & Partners
  178. LG Chem Life Sciences Innovation Center
  179. Logan Medical Devices
  180. LTS Lohmann Therapie-Systeme
  181. Luna Health
  182. Lundbeck
  183. LUTZ
  184. LynJohnston
  185. MACH32
  186. Magnetic Dynamic Technology
  187. Mallinckrodt Pharmaceuticals
  188. Matsushita Electric Industrial
  189. Mayo Foundation for Medical Education and Research (MFMER)
  190. Mcure
  191. MDC Investments
  192. Medical House
  193. Medical Plastic Data Service
  194. Medico
  195. Medicom Innovation Partner (Acquired by Philips-Medisize)
  196. Medihub Pharma
  197. Medimech
  198. MedImmune (a subsidiary of AstraZeneca)
  199. Medimop Medical Projects
  200. Medizin Labortechnik
  201. Medmix
  202. MegaGen
  203. Menarini
  204. Merck
  205. Meridian Medical Technologies
  206. Miaozhen Systems
  207. Milestone Scientific
  208. Mitsubishisteel
  209. Muyuan Foodstuff
  210. My Invu
  211. Mylan (acquired by Viatris)
  212. NA
  213. Nanchang He Tong Trading
  214. Nanjing Hexi Beauty Hospital
  215. Nanjing Institute of Technology 
  216. Nanjing University
  217. Nantong First People's Hospital
  218. Nazhi Medical Equipment Xuzhou
  219. NDM Technologies
  220. Nemoto Kyorindo
  221. New Injection Systems
  222. NEXT Bio-Research Services
  223. Ningbo First Hospital
  224. Ningbo Life Medical Company
  225. Ningbo Ruiai Product Design
  226. Nipro
  227. Nobelpharma
  228. Nordson
  229. Northwest University
  230. Norton Healthcare
  231. Novartis
  232. Novo Nordisk
  233. NPS Pharmaceuticals
  234. Nuance Designs
  235. Oriental Melaka Straits Medical Centre
  236. Oscillate Infotech
  237. Osprey Medical
  238. Otsuka Pharmaceutical
  239. Oval Medical Technologies
  240. Owen Mumford
  241. PA Consulting
  242. Packaging Technologies & Inspection
  243. Painless Technologies
  244. Panasonic Healthcare
  245. Parentral Technologies 
  246. PediaMed Pharmaceuticals
  247. Peking University Shenzhen Hospital 
  248. Pfizer
  249. Pharma Consulting Group International
  250. Pharmacia
  251. Pharmacia & Upjohn
  252. PharmaJet
  253. Philips
  254. Philosys
  255. Pingliang Sanzhu Traditional Chinese Medicine Hospital
  256. Pirouette Medical
  257. Poke
  258. PoongLim Pharmatech
  259. Pos-T-Vac
  260. Preciflex
  261. PrimoJEX
  262. Promisemed Medical Devices
  263. Ptech
  264. Pulse NeedleFree Systems
  265. Qingdao Central Hospital
  266. Qingdao HDMECH Intelligent Equipment
  267. Qingdao Huaao Modern Medical Beauty
  268. Qingdao University
  269. Q-Med
  270. Qualcomm Technologies
  271. QuiO Technologies
  272. Quzhou Feihe Animal Husbandry Technology
  273. Quzhou Youcheng Medical Devices
  274. RapidSOS
  275. Raumedic
  276. Regeneron Pharmaceuticals
  277. Regent's University London
  278. Relevale
  279. Rexam Pharma Le Verpilliere
  280. Reyon Pharmaceutical
  281. Robert Bosch
  282. Rochester Area Consulting Engineers
  283. Ryu Arm
  284. Safety Syringe (A subsidiary of Becton Dickinson)
  285. Sanofi
  286. Sarcos
  287. Schering
  288. Schott Schweiz
  289. Sciele Pharma Cayman
  290. Second Military Medical University
  291. Seedlings Life Science Ventures
  292. Senetek
  293. Seoul National University R&D Research Foundation
  294. Seoul National University School of Dentistry
  295. Shaanxi Ansen Medical Technology Development 
  296. Shaanxi Traditional Chinese Medicine Hospitals
  297. Shaanxi Yifu Beauty Therapy Technology
  298. Shaily Engineering Plastics
  299. Shandong University of Traditional Chinese Medicine
  300. Shandong Wego Prefills Pharmaceutical Packaging
  301. Shandong Xinchuang Biotechnology
  302. Shandong Yixing Medical Devices
  303. Shanghai Bayou Industry & Trade
  304. Shanghai Changzheng Hospital
  305. Shanghai Jiusen Medical Technology
  306. Shanghai Kindly Enterprise Development Group (KDL)
  307. Shanghai Kindly Medical Instruments 
  308. Shanghai Muorange Medical Devices
  309. Shanghai Skeqi Intelligent Equipment Technology
  310. Shanghai Yaojia Medical Devices
  311. Shanghai Youmitai Medical Technology
  312. Shantou Wealy Medical Instrument
  313. Shanxi Academy of Medical Sciences Shanxi Bethune Hospital
  314. Shanxi Medical University
  315. Shaoxing Jizhihui Information Technology
  316. Shenzhen Anke High-tech
  317. Shenzhen Boon Medical Supply
  318. Shenzhen Maiwei BioTech
  319. Shenzhen Mingjian Daily Necessities
  320. Shenzhen Qianhai Kangqiyuan Technology
  321. Shenzhen Ruige Medical Technology
  322. Shenzhen Soga Technology
  323. Shenzhen Weiqi Chemical
  324. Shenzhen Xiaokong Communication Technology
  325. Shenzhen Zhongke Jingyi Design
  326. Shenzhen Zhongxing Technology Development
  327. SHL Group
  328. Shore Group
  329. Showa Chemical
  330. SID Technologies
  331. Silcor Biomed
  332. Sindolor 
  333. SongAm Unc
  334. Southern Medical University
  335. Specialized Health Products
  336. Sterimatic Holdings
  337. Sterling Winthrop Pharmaceuticals
  338. Subot
  339. Summit Street Medical 
  340. Surface Technology International (STI)
  341. Survival Technologies 
  342. Suzhou Hanerxi Medical Device Development
  343. Suzhou Hengrui Hongyuan Medical
  344. Suzhou Jiashu Biomedical Technology
  345. Suzuken
  346. Syntex
  347. Tact IP
  348. Taizhou Qidian Machinery
  349. TCB Medical Devices
  350. Tebro Hindustan
  351. Tech Group Europe
  352. Tecpharma Licensing
  353. Tel Hashomer Medical Research, Infrastructure and Services
  354. Terumo
  355. Teva Pharmaceuticals
  356. The Japan Food Chemical Research Foundation
  357. The Medical House Limited
  358. The Second Affiliated Hospital of Nanchang University
  359. The Third Affiliated Hospital of Zhejiang Chinese Medical University
  360. Thomas Jefferson University
  361. Tianjin Hanaco Medical
  362. Tianjin Keruisheng Technology
  363. Tianjin Puluoxian Science And Technology
  364. Tianjin Yiteng Shengjie Medical Instrument
  365. Tina Hetting Holding
  366. Todo Kogyo
  367. Tongji University
  368. UCB Biopharma
  369. Ulrich Medical USA
  370. Union Medico
  371. Unitract Syringe
  372. University Hospitals Case Medical Center
  373. University of Antwerp
  374. University of Cape Town
  375. University of Florida
  376. University of Saskatchewan
  377. University of South China 
  378. University of Washington
  379. Valois
  380. Valtronic
  381. Verily
  382. Vetter Pharma
  383. Visionary Medical Supplies
  384. Vita Invest Collective Foundation
  385. W. L. Gore & Associates
  386. Washington Biotechnology (WBI)
  387. Wenzhou Medical University
  388. West Pharmaceutical Services
  389. West Virginia University
  390. Weston Medical Publishing
  391. White Innovation
  392. Windgap Medical
  393. Wockhardt
  394. Wuhan Jinwansu Medical Equipment
  395. Wuhu Tong Quan Electronic And Electrical Technology Enterprise
  396. Wuxi Anzhizhuo Medical Treatment Robot
  397. WuXi Biologics
  398. Xi'an Polytechnic University
  399. Xiangya Hospital 
  400. Xiaogan Kuixing Machinery Tech
  401. Yih Hoong Enterprise
  402. Yingtai (Suzhou) Medical Technology
  403. YOFiMeter
  404. Yonsei University
  405. Youwo (Guangzhou) Medical Device
  406. Ypsomed
  407. Zaozhuang Dumi Information Technology
  408. Zhejiang Kangrui Apparatus Technology
  409. Zhejiang Kindly Medical Devices
  410. Zhejiang Ocean University
  411. Zhimai (Shanghai) Robot

Source 1: https://www.sciencedirect.com/science/article/pii/S1319016421001821
Source 2: https://aapsopen.springeropen.com/articles/10.1186/s41120-018-0027-z

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