Automatic Aseptic Sampling Market

Automatic Aseptic Sampling Market Overview

The automatic aseptic sampling market is estimated to be worth $113 million in 2022 and is expected to grow at compounded annual growth rate (CAGR) of 20% during the forecast period. During each stage of biopharmaceutical manufacturing process, it is essential to ensure that the bioprocess variables and parameters are under control. Sampling is considered to be an important step in the bioprocess. However, there are several challenges associated with conventional, manual aseptic sampling technique, such as high risk of contamination of the sample, high labor costs, operator-to-operator deviations during sampling and sample preparation, lower sample frequency rates and no real-time availability of data. This has created a demand for systems that allow aseptic sampling and handling of samples, reduce errors, and increase reproducibility. As a result, automatic sampling systems have emerged to be the most appropriate solution as these systems have the potential to address a number of challenges associated with manual sampling method and offer various additional benefits including real-time data monitoring, reduction in deviations by around 65% and increase in the overall productivity up to 80%. Moreover, automated sampling systems ensure that the processes continue to run within precise limits and make the necessary adjustments, while minimizing the risk of human errors, improving the overall product quality, timely monitoring critical process parameters, bringing tangible cost benefits and increased throughput.

Several companies are actively engaged in the manufacturing of automatic sampling systems and automatic sample preparation systems that can be used across various scale of operations in biopharmaceutical manufacturing. These systems have diverse applications, including bioprocess / analyte monitoring, fraction collection, data management and advanced process control / feedback control in biotechnology, pharmaceutical, chemical, food and cosmetic industries. In addition, automatic sampling systems use process analytical technology (PAT) that can be easily integrated in the bioprocessing unit in order to improve scalability. Further, the field has witnessed several innovations, constantly evolving guidelines for pharmaceutical bioprocessing, mainly based on automation, digitalization and process transparency. It is also important to highlight that several equipment manufacturers offering user-friendly, controlled, and automated systems, have recently emerged. Given the rising interest of stakeholders towards technological advancements and adoption of these systems, we believe that the overall market for automatic sampling in biopharmaceutical applications and the measurement of CQA is anticipated to witness substantial market growth during the forecast period.

Key Companies in Automatic Aseptic Sampling Market

Examples of key companies engaged in automatic aseptic sampling market (which have also been profiled in this market report; the complete list of companies is available in the full report) include Agilent Technologies, Biotage, Cytiva, Flownamics, MGI Tech, Mettler Toledo, Pall Corporation, Shimadzu and SOTAX. This market report includes an easily searchable excel database of all the companies providing automatic aseptic samplers for upstream and downstream biologics manufacturing, worldwide.

Recent Developments in Automatic Aseptic Sampling Market:

Several recent developments have taken place in the field of automatic aseptic sampling market. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.

• In August 2023, Rentschler Biopharma entered into a collaboration with Cell and Gene Therapy Catapult (CGT Catapult) and Refeyn in order to use automated and digital technologies to improve AAV manufacturing for gene therapies. 
• In February 2023, Biosero collaborated with AltemisLab with an aim to streamline sample management automation for customers.

Scope of the Report

The ‘Automatic Aseptic Sampling Market in Biopharmaceutical Applications and the Measurement of CQA, 2022-2035: Distribution by Type of Monitoring Method (On-line, Off-line and At-line), Bioprocessing Method (Upstream and Downstream), Working Volume (Less than 10 mL, 10-50 mL, 51-100 mL and more than 100 mL), Scalability (Lab Scale, Pilot Scale and Commercial Scale), Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World): Industry Trends and Global Forecasts, 2022-2035’ market report features an extensive study on the current market landscape, market size, market share, market forecast, market outlook and future opportunities for automatic aseptic sampling market. Due to the growing demand for biologics and stringent regulatory guidelines, the biopharmaceutical industry has shifted to using automatic sampling methods, which offer reliable systems for transferring bioprocess samples directly from bioreactors to analytical devices while maintaining the process sterility and integrity. In addition, it features an elaborate discussion on the likely opportunity for the players engaged in automatic aseptic sampling market, over the next decade. Amongst other elements, the market research report includes:

• A detailed assessment of the current market landscape of automatic sampling systems, featuring a detailed analysis of these systems based on several parameters, such as type of monitoring method, type of sampling unit(s), availability of pump / probe, type of module, automated software, type of vessel, vessel fabrication material, type of analyte monitored, type of analyzer, number of sampling vessels, working volume, operating temperature, end user industry, scalability and applications of the system. In addition, the chapter includes analysis of automatic sampling system developers, along with information on their year of establishment, company size, location of headquarters and leading players (in terms of number of systems being offered).
• A competitiveness analysis of automatic sampling systems manufacturers based on various relevant parameters, such as overall experience of the company (in terms of number of years since it was established), product portfolio strength (in terms of number of automatic sampling systems manufactured and type of monitoring method) and portfolio diversity (in terms of type of sampling unit, end user industry, scalability and applications).
• Elaborate profiles of prominent players engaged in automatic aseptic sampling market. Each profile includes a brief overview of the company, details related to its financial information (if available), information on product portfolio, recent developments and an informed future outlook.
• A detailed market landscape of automatic sample collection / preparation systems, based on a several relevant parameters, such as system category, system classification, type of monitoring method, type of sampling unit, type of module, working volume, type of analyzer, end user industry and scalability of the products. In addition, the chapter includes a list of players engaged in developing automatic sample collection / preparation systems along with information on their year of establishment, company size, location of headquarters. Further, it also highlights the leading manufacturers of automatic sample collection / preparation systems (in terms of the number of systems manufactured).
• Detailed profiles of the players offering automatic sample collection / preparation systems. It includes a brief overview of the company, details of its product portfolio, and a section on recent developments and an informed future outlook.
• An insightful analysis of the patents filed / granted for automatic sampling systems, since 2016, taking into consideration various relevant parameters, such as type of patent, publication year, geographical location, CPC symbols, emerging focus areas, type of organization, leading players (in terms of number of patents granted / filed in the given time period) and patent characteristics. In addition, the chapter includes a detailed patent benchmarking and an insightful valuation analysis.
• An analysis of various developments / recent trends related to automatic sampling systems, offering insights on recent global events related to automatic sampling systems, and partnerships and collaborations established within the industry.
• A discussion on affiliated trends, key drivers and challenges, under a SWOT framework, featuring a Harvey ball analysis, highlighting the relative impact of each SWOT parameter on the overall automatic sampling systems market.
• A qualitative analysis, highlighting the five competitive forces prevalent in automatic aseptic sampling market, including threats of new entrants, bargaining power of customers, bargaining power of automatic sampling system manufacturers, threats of substitute products and rivalry among existing competitors.

The key objective of automatic aseptic sampling market report is to provide a detailed market analysis in order to estimate the existing market size, market value, statistics and future opportunity for automatic aseptic sampling market during the forecast period. We have provided informed estimates of the likely evolution of the market in the short to mid-term and long term, for the forecast period 2022-2035. Our year-wise projections of the current and future opportunity have further been segmented based on relevant parameters, such as type of monitoring method (on-line, off-line and at-line), bioprocessing method (upstream and downstream), working volume (less than 10 ml, 10-50 ml, 51-100 ml and more than 100 ml), scalability (lab scale, pilot scale and commercial scale), and key geographical regions (North America, Europe, Asia-Pacific and Rest of the World). In order to account for future uncertainties and to add robustness to our model, we have provided three market forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry’s growth.

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this market research report are in USD, unless otherwise specified.

Frequently Asked Questions

Question 1: What is automatic aseptic sampling?

Answer: An automatic sampler is a device which is coupled with another analytical device in order to provide samples on a periodic basis for analytical procedures in biologics manufacturing.

Question 2: How big is the automatic aseptic sampling market?

Answer: The automatic aseptic sampling market size is estimated to be worth $113 million in 2022.

Question 3: What is the projected market growth of the automatic aseptic sampling market?

Answer: The automatic aseptic sampling market is expected to grow at compounded annual growth rate (CAGR) of 20% during the forecast period 2022 - 2035.

Question 4: Who are the leading players in the automatic aseptic sampling market?

Answer: Examples of key companies engaged in automatic aseptic sampling market (which have also been profiled in this market report; the complete list of companies is available in the full report) include Agilent Technologies, Biotage, Cytiva, Flownamics, MGI Tech, Mettler Toledo, Pall Corporation, Shimadzu and SOTAX.

Question 5: How many companies presently claim to provide automatic samplers in the automatic aseptic sampling market?

Answer: Presently, over 40 companies are engaged in the automatic aseptic sampling market, providing more than 55 systems, globally.

Question 6: Which region is the hub for companies engaged in the automatic aseptic sampling market?

Answer: North America presently harbors the majority of the companies engaged in the automatic aseptic sampling market, with close to 40% of the companies being established in this region.

Question 7: How many patents related to automatic samplers have been filed / granted over the last few years?

Answer: Since 2016, over 400 patents related to automatic samplers have been filed / granted, worldwide.