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Report Description
The global CRISPR-based genome editing service market is expected to grow from $644 million to $5,882 million by 2030, at a compounded annual growth rate (CAGR) of ~22%. The 1970s witnessed the introduction of one of the most revolutionary advances in biotechnology, when Hamilton Smith (a molecular biologist at Johns Hopkins University School of Medicine) purified the first site-specific restriction enzyme, called Hind II. This development enabled the scientific community to devise the means to manipulate living organisms at the genetic level, opening up a plethora of opportunities in fundamental and applied life science research. Soon after, in the 1980s, the US FDA approved the world’s first genetically engineered drug, which was human insulin marketed under the brand name HUMULIN®. Genetic engineering and genome editing concepts have evolved significantly over the last two decades, with the development of a variety of versatile DNA modulation technologies including zinc finger nucleases, transcription activator-like effector-based nucleases (TALENs), and the clustered regularly interspaced short palindromic repeats (CRISPR). These developments have enabled medical researchers to perform an array of gene / cell line engineering experiments, including gene knockdowns, gene overexpressions and single base editing, for a variety of R&D applications. It is worth highlighting that, of all the available genome manipulation technologies, CRISPR is currently considered to be the most popular tool, owing to its fast, accurate, and cost-effective approach. In fact, in 2018, scientists Emmanuelle Charpentier, Jennifer Doudna, and Virginijus Siksnys were felicitated for their pioneering efforts on the CRISPR-Cas9 technology, with the prestigious Kavli Prize in Nanoscience.
Currently, there is an evident increase in demand for complex biological therapies (including regenerative medicine products), which has created an urgent need for robust genome editing techniques. The biopharmaceutical pipeline includes close to 500 gene therapies, several of which are being developed based on the CRISPR technology. Recently, in July 2019, a first in vivo clinical trial for a CRISPR-based therapy was initiated. However, successful gene manipulation efforts involve complex experimental protocols and advanced molecular biology centered infrastructure. Therefore, many biopharmaceutical researchers and developers have demonstrated a preference to outsource such operations to capable contract service providers. Consequently, the genome editing contract services market was established and has grown to become an indispensable segment of the modern healthcare industry, offering a range of services, such as gRNA design and construction, cell line development (involving gene knockout, gene knockin, tagging and others) and transgenic animal model generation (such as knockout mice). Additionally, there are several players focused on developing advanced technology platforms that are intended to improve / augment existing gene editing tools, especially the CRISPR-based genome editing processes. Given the rising interest in personalized medicine, a number of strategic investors are presently willing to back genetic engineering focused initiatives. Prevalent trends indicate that the market for CRISPR-based genome editing services is likely to grow at a significant pace in the foreseen future.
The “Genome Editing Services Market: Focus on CRISPR, 2019-2030” report features an extensive study of the current landscape of CRISPR-based genome editing service providers. The study presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain, across different geographical regions. Amongst other elements, the report includes:
One of the key objectives of the report was to evaluate the current opportunity and the future potential of CRISPR-based genome editing services market. We have provided an informed estimate of the likely evolution of the market in the short to mid-term and long term, for the period 2019-2030. In addition, we have segmented the future opportunity across [A] type of services offered (gRNA construction, cell line engineering and animal model generation), [B] type of cell line used (mammalian, microbial, insect and others) and [C] different geographical regions (North America, Europe, Asia Pacific and rest of the world). To account for the uncertainties associated with the CRISPR-based genome editing services market and to add robustness to our model, we have provided three forecast scenarios, portraying the conservative, base and optimistic tracks of the market’s evolution.
The research, analysis and insights presented in this report are backed by a deep understanding of key insights generated from both secondary and primary research. All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.
Contents
Chapter 2 is an executive summary of the insights captured in our research. The summary offers a high-level view on the likely evolution of the CRISPR-based genome editing services market in the short to mid-term, and long term.
Chapter 3 provides a brief overview, history and applications of genome editing. It includes detailed discussion on the different types of currently available genome editing techniques. In addition, the chapter provides details of CRISPR technology along with the information on role of CRISPR / Cas in bacterial adaptive immunity, key CRISPR / Cas systems and components of CRISPR / Cas system. Further, it includes details on protocol associated with CRISPR-based genome editing, applications of CRISPR and associated key challenges and future perspectives.
Chapter 4 provides a comprehensive view on the current landscape of CRISPR-based genome editing service providers. It includes information related to over 80 companies that claim to offer CRISPR-based genome editing services, featuring an in-depth analyses of the players based on their service offering including gRNA service (gRNA design and gRNA construction), availability of gRNA format (plasmid, lentivirus, AAV, adenovirus and others), type of endonuclease (Cas9, Cpf1 and others), availability of Cas9 format (mRNA, plasmid, lentivirus, AAV, protein and others), type of cell line engineering offering (knockout, knockin, tagging / reporters and others), type of cell line (stem cell lines, human cell lines, other mammalian cell lines and others (microbial, insects and others)), type of animal model generation offering (mice / mouse, rat, zebrafish, C.elegans and others), availability of CRISPR libraries and important service provider details (year of establishment, headquarter location(s), company size).
Chapter 5 features a comprehensive 2X2 analysis offering a comparative summary of all the CRISPR-based genome editing service providers that we came across during our research. The analysis compares the aforementioned companies within three peer-groups, established based on size of employee base (small-sized (1-200 employees), mid-sized (>201-1,000 employees) and large (>1,000 employees)). The companies were compared based on their genome editing capabilities (including gRNA service(s), endonuclease service(s), cell line service(s), animal model generation service(s), CRISPR library(s)) and supplier power.
Chapter 6 features profiles of CRISPR-based genome editing service providers (shortlisted based on strength of service portfolio). Each profile features an overview of the company, its financial performance (if available), brief details of genome editing service portfolio, recent developments and an informed future outlook.
Chapter 7 provides an in-depth patent analysis to provide an overview of how the industry is evolving from the R&D perspective. For this analysis, we considered those patents that have been filed since 2006 related to CRISPR technology. The analysis also highlights the key trends associated with these patents, including type of patent (granted patent, patent application and others), publication year and application year, geography (North America, Europe, Asia-Pacific and Rest of the World), CPC symbols (Top 15 CPC symbols), key focus areas, leading industry / non-industry players, patent benchmarking analysis and patent valuation analysis.
Chapter 8 provides information on close to 2,200 grants that were awarded to research institutes engaged in projects related to CRISPR technology, between 2015 and 2019 (till September). The analysis also highlights important parameters associated with grants, such as year of award, amount awarded, administering institute center, support period, funding mechanism, type of grant application, grant activity, type of recipient organization, regional distribution of recipient organization, prominent project leaders and emerging focus areas. It also features a detailed multivariate grant attractiveness analysis based on the amount awarded, support period, grant type and funding mechanism.
Chapter 9 provides details of innovative technology platforms (such as integration of delivery platforms, enzyme technologies, protein technologies and others with the fundamental CRISPR technology) to improve CRISPR processes. It includes the list of companies that are focused on the development of these technologies along with details on a number of parameters, such as year of establishment, headquarter location(s), company size, company expertise and technology details (name, focus and key features). In addition, it includes tabulated profiles of key technology providers, with details on company overview, funding and collaboration instances. Further, the chapter highlights a list of companies that offer CRISPR design tools and kits.
Chapter 10 features an insightful analysis, highlighting potential strategic partners (for instance, drug developers) for CRISPR-based genome editing service providers, based on multiple parameters, such as type of therapy, pipeline strength, pipeline maturity, company strength and therapeutic area. The analysis aims to provide the necessary inputs to the stakeholders, enabling them to make the right decisions to conduct research work with the help the appropriate partner entities.
Chapter 11 features a comprehensive market forecast, highlighting the future potential of CRISPR-based genome editing services market till 2030. The projected opportunity has been further analyzed to develop a better perspective related to its distribution across [A] type of services (gRNA construction, cell line engineering and animal model generation), [B] type of cell line (mammalian, microbial, insect and others) and [C] different global regions (North America, Europe, Asia-Pacific and rest of the world).
Chapter 12 provides a discussion on important industry-specific trends, key market drivers and challenges, under a SWOT framework, featuring a qualitative Harvey ball analysis, that highlights the relative impact of each SWOT parameter on the overall CRISPR-based genome editing services market.
Chapter 13 is a collection of transcripts of the interviews conducted with representatives from renowned organizations that are engaged in the CRISPR technology domain.
Chapter 14 is an appendix, which provides tabulated data and numbers for all the figures in the report.
Chapter 15 is an appendix that provides the list of companies and organizations that have been mentioned in the report.
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Context and Background
3.2. Overview of Genome Editing
3.3. History of Genome Editing
3.4. Applications of Genome Editing
3.5. Genome Editing Techniques
3.5.1. Mutagenesis
3.5.2 Conventional Homologous Recombination
3.5.3 Single Stranded Oligo DNA Nucleotides Homologous Recombination
3.5.4. Homing Endonuclease Systems (Adeno Associated Virus System)
3.5.5. Protein-based Nuclease Systems
3.5.5.1. Meganucleases
3.5.5.2. Zinc Finger Nucleases
3.5.5.3. Transcription Activator-like Effector Nucleases
3.5.6. DNA Guided Systems
3.5.6.1. Peptide Nucleic Acids
3.5.6.2. Triplex Forming Oligonucleotides
3.5.6.3. Structure Guided Endonucleases
3.5.7. RNA Guided Systems
3.5.7.1. CRISPR-Cas9
3.5.7.2. Targetrons
3.6. CRISPR-based Genome Editing
3.6.1. Role of CRISPR-Cas in Adaptive Immunity in Bacteria
3.6.2. Key CRISPR-Cas Systems
3.6.3. Components of CRISPR-Cas System
3.6.4. Protocol for CRISPR-based Genome Editing
3.7. Applications of CRISPR
3.7.1. Development of Therapeutic Interventions
3.7.2. Augmentation of Artificial Fertilization Techniques
3.7.3. Development of Genetically Modified Organisms
3.7.4. Production of Biofuels
3.7.5. Other Bioengineering Applications
3.8. Key Challenges and Future Perspectives
4. CRISPR-BASED GENOME EDITING SERVICE PROVIDERS: CURRENT MARKET LANDSCAPE
4.1. Chapter Overview
4.2. CRISPR-based Genome Editing Service Providers: Overall Market Landscape
4.2.3. Analysis by Type of Service Offering
4.2.4. Analysis by Type of gRNA Format
4.2.5. Analysis by Type of Endonuclease
4.2.6. Analysis by Type of Cas9 Format
4.2.7. Analysis by Type of Cell Line Engineering Offering
4.2.8. Analysis by Type of Animal Model Generation Offering
4.2.9. Analysis by Availability of CRISPR Libraries
4.2.10. Analysis by Year of Establishment
4.2.11. Analysis by Company Size
4.2.12. Analysis by Geographical Location
4.2.13. Logo Landscape: Distribution by Company Size and Location of Headquarters
5. COMPANY COMPETITIVENESS ANALYSIS
5.1. Chapter Overview
5.2. Methodology
5.3. Assumptions and Key Parameters
5.4. CRISPR-based Genome Editing Service Providers: Competitive Landscape
5.4.1. Small-sized Companies
5.4.2. Mid-sized Companies
5.4.3. Large Companies
6. COMPANY PROFILES
6.1. Chapter Overview
6.2. Applied StemCell
6.2.1. Company Overview
6.2.2. Service Portfolio
6.2.3. Recent Developments and Future Outlook
6.3. BioCat
6.3.1. Company Overview
6.3.2. Service Portfolio
6.3.3. Recent Developments and Future Outlook
6.4. Biotools
6.4.1. Company Overview
6.4.2. Service Portfolio
6.4.3. Recent Developments and Future Outlook
6.5. Charles River Laboratories
6.5.1. Company Overview
6.5.2. Financial Information
6.5.3. Service Portfolio
6.5.4. Recent Developments and Future Outlook
6.6. Cobo Scientific
6.6.1. Company Overview
6.6.2. Service Portfolio
6.6.3. Recent Developments and Future Outlook
6.7. Creative Biogene
6.7.1. Company Overview
6.7.2. Service Portfolio
6.7.3. Recent Developments and Future Outlook
6.8. Cyagen Biosciences
6.8.1. Company Overview
6.8.2. Service Portfolio
6.8.3. Recent Developments and Future Outlook
6.9. GeneCopoeia
6.9.1. Company Overview
6.9.2. Service Portfolio
6.9.3. Recent Developments and Future Outlook
6.10. Horizon Discovery
6.10.1. Company Overview
6.10.2. Financial Information
6.10.3. Service Portfolio
6.10.4. Recent Developments and Future Outlook
6.11. NemaMetrix
6.11.1. Company Overview
6.11.2. Service Portfolio
6.11.3. Recent Developments and Future Outlook
6.12. Synbio Technologies
6.12.1. Company Overview
6.12.2. Service Portfolio
6.12.3. Recent Developments and Future Outlook
6.13. Thermo Fisher Scientific
6.13.1. Company Overview
6.13.2. Financial Information
6.13.3. Service Portfolio
6.13.4. Recent Developments and Future Outlook
7. PATENT ANALYSIS
7.1. Chapter Overview
7.2. Scope and Methodology
7.3. CRISPR-based Genome Editing: Patent Analysis
7.3.1. Analysis by Application Year and Publication Year
7.3.2. Analysis by Geography
7.3.3. Analysis by CPC Symbols
7.3.4. Emerging Focus Areas
7.3.5. Leading Players: Analysis by Number of Patents
7.4. CRISPR-based Genome Editing: Patent Benchmarking Analysis
7.4.1. Analysis by Patent Characteristics
7.5. Patent Valuation Analysis
8. ACADEMIC GRANT ANALYSIS
8.1. Chapter Overview
8.2. Scope and Methodology
8.3. Grants Awarded by the National Institutes of Health for CRISPR-based
8.3.1. Year-wise Trend of Grant Award
8.3.2. Analysis by Amount Awarded
8.3.3. Analysis by Administering Institutes
8.3.4. Analysis by Support Period
8.3.5. Analysis by Funding Mechanism
8.3.6. Analysis by Type of Grant Application
8.3.7. Analysis by Grant Activity
8.3.8. Analysis by Recipient Organization
8.3.9. Regional Distribution of Grant Recipient Organization
8.3.10. Prominent Project Leaders: Analysis by Number of Grants
8.3.11. Emerging Focus Areas
8.3.12. Grant Attractiveness Analysis
9. CASE STUDY: ADVANCED CRISPR-BASED TECHNOLOGIES / SYSTEMS AND TOOLS
9.1. Chapter Overview
9.2. CRISPR-based Technology Providers
9.2.1. Analysis by Year of Establishment and Company Size
9.2.2. Analysis by Geographical Location and Company Expertise
9.2.3. Analysis by Focus Area
9.2.4. Key Technology Providers: Company Snapshots
9.2.4.1. APSIS Therapeutics
9.2.4.2. Beam Therapeutics
9.2.4.3. CRISPR Therapeutics
9.2.4.4. Editas Medicine
9.2.4.5. Intellia Therapeutics
9.2.4.6. Jenthera Therapeutics
9.2.4.7. KSQ Therapeutics
9.2.4.8. Locus Biosciences
9.2.4.9. Refuge Biotechnologies
9.2.4.10. Repare Therapeutics
9.2.4.11. SNIPR BIOME
9.2.5. Key Technology Providers: Summary of Venture Capital Investments
9.3. List of CRISPR Kit Providers
9.4. List of CRISPR Design Tool Providers
10. POTENTIAL STRATEGIC PARTNERS
10.1. Chapter Overview
10.2. Scope and Methodology
10.3. Potential Strategic Partners for Genome Editing Service Providers
10.3.1. Key Industry Partners
10.3.1.1. Most Likely Partners
10.3.1.2. Likely Partners
10.3.1.3. Less Likely Partners
10.3.2. Key Non-Industry / Academic Partners
10.3.2.1. Most Likely Partners
10.3.2.2. Likely Partners
10.3.2.3. Less Likely Partners
11. MARKET FORECAST
11.1. Chapter Overview
11.2. Forecast Methodology and Key Assumptions
11.3. Overall CRISPR-based Genome Editing Services Market, 2019-2030
11.4. CRISPR-based Genome Editing Services Market: Distribution by Regions, 2019-2030
11.4.1. CRISPR-based Genome Editing Services Market in North America, 2019-2030
11.4.2. CRISPR-based Genome Editing Services Market in Europe, 2019-2030
11.4.3. CRISPR-based Genome Editing Services Market in Asia Pacific, 2019-2030
11.4.4. CRISPR-based Genome Editing Services Market in Rest of the World, 2019-2030
11.5. CRISPR-based Genome Editing Services Market: Distribution by Type of Services, 2019-2030
11.5.1. CRISPR-based Genome Editing Services Market for gRNA Construction, 2019-2030
11.5.1.1. CRISPR-based Genome Editing Services Market for gRNA Construction in North America, 2019-2030
11.5.1.2. CRISPR-based Genome Editing Services Market for gRNA Construction in Europe, 2019-2030
11.5.1.3. CRISPR-based Genome Editing Services Market for gRNA Construction in Asia Pacific, 2019-2030
11.5.1.4. CRISPR-based Genome Editing Services Market for gRNA Construction in Rest of the World, 2019-2030
11.6.1. CRISPR-based Genome Editing Services Market for Cell Line Engineering, 2019-2030
11.6.1.1. CRISPR-based Genome Editing Services Market for Cell Line Engineering in North America, 2019-2030
11.6.1.2. CRISPR-based Genome Editing Services Market for Cell Line Engineering in Europe, 2019-2030
11.6.1.3. CRISPR-based Genome Editing Services Market for Cell Line Engineering in Asia Pacific, 2019-2030
11.6.1.4.
11.7.1. CRISPR-based Genome Editing Services Market for Animal Model Generation, 2019-2030
11.7.1.1. CRISPR-based Genome Editing Services Market for Animal Model Generation in North America, 2019-2030
11.7.1.2. CRISPR-based Genome Editing Services Market for Animal Model Generation in Europe, 2019-2030
11.7.1.3. CRISPR-based Genome Editing Services Market for Animal Model Generation in Asia Pacific, 2019-2030
11.7.1.4. CRISPR-based Genome Editing Services Market for Animal Model Generation in Rest of the World, 2019-2030
11.8. CRISPR-based Genome Editing Services Market: Distribution by Type of Cell Line, 2019-2030
11.8.1. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines, 2019-2030
11.8.1.1. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in North America, 2019-2030
11.8.1.2. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Europe, 2019-2030
11.8.1.3. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Asia Pacific, 2019-2030
11.8.1.4. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Rest of the World, 2019-2030
11.9.1. CRISPR-based Genome Editing Services Market for Microbial Cell Lines, 2019-2030
11.9.1.1. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in North America, 2019-2030
11.9.1.2. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Europe, 2019-2030
11.9.1.3. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Asia Pacific, 2019-2030
11.9.1.4. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Rest of the World, 2019-2030
11.10.1. CRISPR-based Genome Editing Services Market for Other Cell Lines, 2019-2030
11.10.1.1. CRISPR-based Genome Editing Services Market for Other Cell Lines in North America, 2019-2030
11.10.1.2. CRISPR-based Genome Editing Services Market for Other Cell Lines in Europe, 2019-2030
11.10.1.3. CRISPR-based Genome Editing Services Market for Other Cell Lines in Asia Pacific, 2019-2030
11.10.1.4. CRISPR-based Genome Editing Services Market for Other Cell Lines in Rest of the World, 2019-2030
12. SWOT ANALYSIS
12.1. Chapter Overview
12.2. SWOT Analysis
12.2.1. Strengths
12.2.2. Weaknesses
12.2.3. Opportunities
12.2.4. Threats
12.2.5. Concluding Remarks
13. EXECUTIVE INSIGHTS
14. APPENDIX 1: TABULATED DATA
15. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS
Figure 3.1. Genome Editing: Historical Milestones
Figure 3.2. Genome Editing Techniques
Figure 3.3. CRISPR-based Genome Editing Protocol
Figure 4.1. CRISPR-based Genome Editing Services: Distribution by Type of Service Offering
Figure 4.2. CRISPR-based Genome Editing Services: Distribution by Type of gRNA Format
Figure 4.3. CRISPR-based Genome Editing Services: Distribution by Type of Endonuclease
Figure 4.4. CRISPR-based Genome Editing Services: Distribution by Type of Cas9 Endonuclease Format
Figure 4.5. CRISPR-based Genome Editing Services: Distribution by Type of Cell Line Engineering
Figure 4.6. CRISPR-based Genome Editing Services: Distribution by Type of Animal Model Generation
Figure 4.7. CRISPR-based Genome Editing Services: Distribution by Availability of CRISPR Libraries
Figure 4.8. CRISPR-based Genome Editing Service Providers: Distribution by Year of Establishment
Figure 4.9. CRISPR-based Genome Editing Service Providers: Distribution by Company Size
Figure 4.10. CRISPR-based Genome Editing Service Providers: Distribution by Geographical Location
Figure 4.11. CRISPR-based Genome Editing Service Providers Logo Landscape: Distribution by Company Size and Location of Headquarters
Figure 5.1. Company Competitiveness Analysis: Assumptions and Key Parameters
Figure 5.2. Company Competitiveness Analysis: Small-sized Players
Figure 5.3. Company Competitiveness Analysis: Mid-sized Players
Figure 5.4. Company Competitiveness Analysis: Large Players
Figure 6.1. Charles River Laboratories: Annual Revenues, 2014–H1 2019 (USD Billion)
Figure 6.2. Horizon Discovery: Annual Revenues, 2014-H1 2019 (EUR Million)
Figure 6.3. Thermo Fisher Scientific: Annual Revenues, 2014-H1 2019 (USD Million)
Figure 7.1. Patent Portfolio: Distribution by Type of Patent
Figure 7.2. Patent Portfolio: Distribution by Application Year
Figure 7.3. Patent Portfolio: Distribution by Publication Year
Figure 7.4. Patent Portfolio: Distribution by Geography
Figure 7.5. Patent Portfolio: Distribution by CPC Symbols
Figure 7.6. Patent Portfolio: Emerging Focus Areas
Figure 7.7. Leading Industry Players: Distribution by Size of Patent Portfolio
Figure 7.8. Leading Non-Industry Players: Distribution by Size of Patent Portfolio
Figure 7.9. Patent Portfolio: Benchmarking by Patent Characteristics
Figure 7.10. Patent Portfolio: Valuation Analysis
Figure 8.1. Academic Grant Analysis: Year-wise Trend of Award
Figure 8.2. Academic Grant Analysis: Distribution by Amount Awarded
Figure 8.3. Academic Grant Analysis: Distribution by Administering Institutes
Figure 8.4. Academic Grant Analysis: Distribution by Support Period
Figure 8.5. Academic Grant Analysis: Distribution by Funding Mechanism
Figure 8.6. Academic Grant Analysis: Distribution by Type of Grant Application
Figure 8.7. Academic Grant Analysis: Distribution by Grant Activity
Figure 8.8. Academic Grant Analysis: Distribution by Recipient Organization
Figure 8.9. Academic Grant Analysis: Regional Distribution of Recipient Organization
Figure 8.10. Prominent Project Leaders: Distribution by Number of Grants Awarded
Figure 8.11. Academic Grant Analysis: Emerging Focus Areas
Figure 8.12. Academic Grant Analysis: Grant Attractiveness Analysis
Figure 9.1. CRISPR-based Technology Providers: Distribution by Year of Establishment
Figure 9.2. CRISPR-based Technology Providers: Distribution by Company Size
Figure 9.3. CRISPR-based Technology Providers: Distribution by Geographical Location and Company Expertise
Figure 9.4. CRISPR-based Technology Providers: Distribution by Focus Area
Figure 9.5. Key CRISPR-based Technology Providers: Venture Capital Investments (USD Million)
Figure 11.1. Overall CRISPR-based Genome Editing Services Market, 2019-2030 (USD Million)
Figure 11.2. CRISPR-based Genome Editing Services Market: Distribution by Regions, 2019-2030 (USD Million)
Figure 11.3. CRISPR-based Genome Editing Services Market in North America, 2019-2030 (USD Million)
Figure 11.4. CRISPR-based Genome Editing Services Market in Europe, 2019-2030 (USD Million)
Figure 11.5. CRISPR-based Genome Editing Services Market in Asia Pacific, 2019-2030 (USD Million)
Figure 11.6. CRISPR-based Genome Editing Services Market in Rest of the World, 2019-2030 (USD Million)
Figure 11.7. CRISPR-based Genome Editing Services Market: Distribution by Type of Services, 2019-2030 (USD Million)
Figure 11.8. CRISPR-based Genome Editing Services Market for gRNA Construction, 2019-2030 (USD Million)
Figure 11.9. CRISPR-based Genome Editing Services Market for gRNA Construction in North America, 2019-2030 (USD Million)
Figure 11.10. CRISPR-based Genome Editing Services Market for gRNA Construction in
Figure 11.11. CRISPR-based Genome Editing Services Market for gRNA Construction in Asia Pacific, 2019-2030 (USD Million)
Figure 11.12. CRISPR-based Genome Editing Services Market for gRNA Construction in Rest of the World, 2019-2030 (USD Million)
Figure 11.13. CRISPR-based Genome Editing Services Market for Cell Line Engineering, 2019-2030 (USD Million)
Figure 11.14. CRISPR-based Genome Editing Services Market for Cell Line Engineering in North America, 2019-2030 (USD Million)
Figure 11.15. CRISPR-based Genome Editing Services Market for Cell Line Engineering in Europe, 2019-2030 (USD Million)
Figure 11.16. CRISPR-based Genome Editing Services Market for Cell Line Engineering in Asia Pacific, 2019-2030 (USD Million)
Figure 11.17. CRISPR-based Genome Editing Services Market for Cell Line Engineering in Rest of the World, 2019-2030 (USD Million)
Figure 11.18. CRISPR-based Genome Editing Services Market for Animal Model Generation, 2019-2030 (USD Million)
Figure 11.19. CRISPR-based Genome Editing Services Market for Animal Model Generation in North America, 2019-2030 (USD Million)
Figure 11.20. CRISPR-based Genome Editing Services Market for Animal Model Generation in Europe, 2019-2030 (USD Million)
Figure 11.21. CRISPR-based Genome Editing Services Market for Animal Model Generation in Asia Pacific, 2019-2030 (USD Million)
Figure 11.22. CRISPR-based Genome Editing Services Market for Animal Model Generation in Rest of the World, 2019-2030 (USD Million)
Figure 11.23. CRISPR-based Genome Editing Services Market: Distribution by Type of Cell Line, 2019-2030 (USD Million)
Figure 11.24. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines, 2019-2030 (USD Million)
Figure 11.25. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in North America, 2019-2030 (USD Million)
Figure 11.26. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Europe, 2019-2030 (USD Million)
Figure 11.27. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Asia Pacific, 2019-2030 (USD Million)
Figure 11.28. CRISPR-based Genome Editing Services Market for Mammalian Cell Lines in Rest of the World, 2019-2030 (USD Million)
Figure 11.29. CRISPR-based Genome Editing Services Market for Microbial Cell Lines, 2019-2030 (USD Million)
Figure 11.30. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in North America, 2019-2030 (USD Million)
Figure 11.31. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Europe, 2019-2030 (USD Million)
Figure 11.32. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Asia Pacific, 2019-2030 (USD Million)
Figure 11.33. CRISPR-based Genome Editing Services Market for Microbial Cell Lines in Rest of the World, 2019-2030 (USD Million)
Figure 11.34. CRISPR-based Genome Editing Services Market for Other Cell Lines, 2019-2030 (USD Million)
Figure 11.35. CRISPR-based Genome Editing Services Market for Other Cell Lines in North America, 2019-2030 (USD Million)
Figure 11.36. CRISPR-based Genome Editing Services Market for Other Cell Lines in Europe, 2019-2030 (USD Million)
Figure 11.37. CRISPR-based Genome Editing Services Market for Other Cell Lines in Asia Pacific, 2019-2030 (USD Million)
Figure 11.38. CRISPR-based Genome Editing Services Market for Other Cell Lines in Rest of the World, 2019-2030 (USD Million)
Figure 12.1. CRISPR-based Genome Editing: SWOT Factors
Figure 12.2. Comparison of SWOT Factors: Harvey Ball Analysis
Table 3.1. Classification of CRISPR-Cas Systems
Table 4.1. List of CRISPR-based Genome Editing Service Providers: Information on Type of Service
Table 4.2. List of CRISPR-based Genome Editing Service Providers: Information on gRNA Format, Type of Endonuclease and Cas9 Endonuclease Format
Table 4.3. List of CRISPR-based Genome Editing Service Providers: Information on Cell Line Engineering Offerings, Animal Model Generation Offerings and Availability of CRISPR Libraries
Table 5.1. Company Competitive Analysis: Small-sized Players
Table 5.2. Company Competitive Analysis: Mid-sized Players
Table 5.3. Company Competitive Analysis: Large Players
Table 6.1. CRISPR-based Genome Editing Services Providers: List of Companies Profiled
Table 6.2. Applied StemCell: Company Overview
Table 6.3. Applied StemCell: CRISPR-based Genome Editing Services
Table 6.4. Applied StemCell: Recent Developments and Future Outlook
Table 6.5. BioCat: Company Overview
Table 6.6. BioCat: CRISPR-based Genome Editing Services
Table 6.7. BioCat: Recent Developments and Future Outlook
Table 6.8. Charles River Laboratories: Company Overview
Table 6.9. Charles River Laboratories: CRISPR-based Genome Editing Services
Table 6.10. Charles River Laboratories: Recent Developments and Future Outlook
Table 6.11. Cobo Scientific: Company Overview
Table 6.12. Cobo Scientific: CRISPR-based Genome Editing Services
Table 6.13. Cobo Scientific: Recent Developments and Future Outlook
Table 6.14. Creative Biogene: Company Overview
Table 6.15. Creative Biogene: CRISPR-based Genome Editing Services
Table 6.16. Creative Biogene: Recent Developments and Future Outlook
Table 6.17. Cyagen Biosciences: Company Overview
Table 6.18. Cyagen Biosciences: CRISPR-based Genome Editing Services
Table 6.19. Cyagen Biosciences: Recent Developments and Future Outlook
Table 6.20. GeneCopoeia: Company Overview
Table 6.21. GeneCopoeia: CRISPR-based Genome Editing Services
Table 6.22. GeneCopoeia: Recent Developments and Future Outlook
Table 6.23. Horizon Discovery: Company Overview
Table 6.24. Horizon Discovery: CRISPR-based Genome Editing Services
Table 6.25. Horizon Discovery: Recent Developments and Future Outlook
Table 6.26. NemaMetrix: Company Overview
Table 6.27. NemaMetrix: CRISPR-based Genome Editing Services
Table 6.28. NemaMetrix: Recent Developments and Future Outlook
Table 6.29. Synbio Technologies: Company Overview
Table 6.30. Synbio Technologies: CRISPR-based Genome Editing Services
Table 6.31. Synbio Technologies: Recent Developments and Future Outlook
Table 6.32. Thermo Fisher Scientific: Company Overview
Table 6.33. Thermo Fisher Scientific: CRISPR-based Genome Editing Services
Table 6.34. Thermo Fisher Scientific: Recent Developments and Future Outlook
Table 8.1. Grant Analysis: List of Most Attractive Grants
Table 9.1. List of CRISPR-based Technology Providers
Table 9.2. List of CRISPR-based Technology Providers: Information on Technology
Table 9.3. Beam Therapeutics: Funding Instances
Table 9.4. Beam Therapeutics: Collaborations
Table 9.5. CRISPR Therapeutics: Funding Instances
Table 9.6. CRISPR Therapeutics: Collaborations
Table 9.7. Editas Medicine: Funding Instances
Table 9.8. Editas Medicine: Collaborations
Table 9.9. KSQ Therapeutics: Funding Instances
Table 9.10. Locus Biosciences: Funding Instances
Table 9.11. Locus Biosciences: Collaborations
Table 9.12. Refuge Biotechnologies: Funding Instances
Table 9.13. Refuge Biotechnologies: Collaborations
Table 9.14. Repare Therapeutics: Funding Instances
Table 9.15. SNIPR BIOME: Funding Instances
Table 9.16. Intellia Therapeutics: Funding Instances
Table 9.17. Intellia Therapeutics: Collaborations
Table 9.18. List of CRISPR Kit Providers
Table 9.19. List of CRISPR Design Tool Providers
Table 10.1. Industry Players: Most Likely Partners
Table 10.2. Industry Players: Likely Partners
Table 10.3. Industry Players: Less Likely Partners
Table 10.4. Non-Industry Players: Most Likely Partners
Table 10.5. Non-Industry Players: Likely Partners
Table 10.6. Non-Industry Players: Less Likely Partners
Table 14.1. CRISPR-based Genome Editing Services: Distribution by Type of Service Offering
Table 14.2. CRISPR-based Genome Editing Services: Distribution by Type of gRNA Format
Table 14.3. CRISPR-based Genome Editing Services: Distribution by Type of Endonuclease
Table 14.4. CRISPR-based Genome Editing Services: Distribution by Type of Cas9 Endonuclease Format
Table 14.5. CRISPR-based Genome Editing Services: Distribution by Type of Cell Line Engineering
Table 14.6. CRISPR-based Genome Editing Services: Distribution by Type of Animal Model Generation
Table 14.7. CRISPR-based Genome Editing Services: Distribution by Availability of CRISPR Libraries
Table 14.8. CRISPR-based Genome Editing Service Providers: Distribution by Year of Establishment
Table 14.9. CRISPR-based Genome Editing Service Providers: Distribution by Company Size
Table 14.10. CRISPR-based Genome Editing Service Providers: Distribution by Geographical Location
Table 14.11. CRISPR-based Genome Editing Service Providers Logo Landscape: Distribution by Company Size and Location of Headquarters
Table 14.12. Charles River Laboratories: Annual Revenues, 2014–H1 2019 (USD Billion)
Table 14.13. Horizon Discovery: Annual Revenues, 2014-H1 2019 (EUR Million)
Table 14.14. Thermo Fisher Scientific: Annual Revenues, 2014-H1 2019 (USD Million)
Table 14.15. Patent Portfolio: Distribution by Type of Patent
Table 14.16. Patent Portfolio: Distribution by Application Year
Table 14.17. Patent Portfolio: Distribution by Publication Year
Table 14.18. Patent Portfolio: Distribution by Geography
Table 14.19. Leading Industry Players: Distribution by Size of Patent Portfolio
Table 14.20. Leading Non-Industry Players: Distribution by Size of Patent Portfolio
Table 14.21. Patent Portfolio: Valuation Analysis
Table 14.22. Academic Grant Analysis: Year-wise Trend of Award
Table 14.23. Academic Grant Analysis: Distribution by Amount Awarded
Table 14.24. Academic Grant Analysis: Distribution by Administering Institutes
Table 14.25. Academic Grant Analysis: Distribution by Support Period
Table 14.26. Academic Grant Analysis: Distribution by Funding Mechanism
Table 14.27. Academic Grant Analysis: Distribution by Type of Grant Application
Table 14.28. Academic Grant Analysis: Distribution by Grant Activity
Table 14.29. Academic Grant Analysis: Distribution by Recipient Organization
Table 14.30. Prominent Project Leaders: Distribution by Number of Grants Awarded
Table 14.31. Academic Grant Analysis: Grant Attractiveness Analysis
Table 14.32. CRISPR-based Technology Providers: Distribution by Year of Establishment
Table 14.33. CRISPR-based Technology Providers: Distribution by Company Size
Table 14.34. CRISPR-based Technology Providers: Distribution by Focus Area
Table 14.35. Key CRISPR-based Technology Providers: Venture Capital Investments (USD Million)
Table 14.36. Overall CRISPR-based Genome Editing Services Market, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.37. CRISPR-based Genome Editing Services Market: Distribution by Regions, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.38. CRISPR-based Genome Editing Services Market in North America, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.39. CRISPR-based Genome Editing Services Market in Europe, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.40. CRISPR-based Genome Editing Services Market in Asia Pacific, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.41. CRISPR-based Genome Editing Services Market in Rest of the World, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.42. CRISPR-based Genome Editing Services Market: Distribution by Type of Services, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.43. CRISPR-based Genome Editing Services Market for gRNA Construction, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.44. CRISPR-based Genome Editing Services Market for gRNA Construction in North America, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.45. CRISPR-based Genome Editing Services Market for gRNA Construction in Europe, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.46. CRISPR-based Genome Editing Services Market for gRNA Construction in Asia Pacific, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.47. CRISPR-based Genome Editing Services Market for gRNA Construction in Rest of the World, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.48. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.49. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.50. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.51. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.52. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.53. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.54. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.55. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.56. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.57. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.58. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.59. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.60. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.61. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.62. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.63. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.64. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.65. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.66. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.67. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.68. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.69. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.70. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.71. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.72. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)
Table 14.73. CRISPR-based Genome Editing Services Market for Cell Line Engineering, Conservative, Base and Optimistic Scenarios, Conservative, Base and Optimistic Scenarios, 2019-2030 (USD Million)