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Report Description
The global non-hormonal therapies market is estimated to be worth USD $1.8 billion in 2021 and is projected to reach $10.9 billion in 2030. According to the World Health Organization (WHO), sexual and reproductive health-related conditions represent around one third of all clinical conditions prevalent among women between the ages of 15 and 44 years. The human female reproductive system is complex and governed primarily by two hormones, estrogen and progesterone. Any imbalance in the levels of these hormones materializes in the form of a disease, and / or mood related disorders; in fact, women are more prone to experiencing various forms of anxiety, depression and certain physical symptoms that cannot yet be explained medically, as compared to men. Since hormones are responsible for almost all of the concerns associated with reproductive health, a number of hormone regulating interventions have been developed, and are available, for the treatment / prevention of the clinical conditions that are unique to women. This form of therapy has been proven to be both viable and effective, and have been in use since the 1960s. Such therapies gained better traction as mainstream healthcare solutions after clinical trials were conducted, proving their efficacy, in the late 1990s. Despite the vast success of using hormones as therapeutics, later studies reflected a positive correlation between the use of such interventions and several unwanted side effects, including the risk of developing hormone dependent cancers.
In recent years, the development and introduction of non-hormonal alternatives has revolutionized women’s healthcare. Brisdelle® was the first of such products, approved in 2013 for the management of hot flashes in menopausal women. Till date, 21 non-hormonal therapies (recent examples include Oriahnn™, Phexxi™ and Esmya®) have been approved. Further, several such non-hormonal product candidates are under evaluation across different stages of product development. The inherent advantages of non-hormonal therapies, such as better safety profile, ability to maintain hormonal balance and relatively short treatment courses, over their hormonal counterparts have been demonstrated both in clinical trials and post product approval studies. As a result, such products are currently preferred over hormone-based therapies, and the non-hormonal therapy pipeline is expected to continue to steadily expand over the coming years.It is worth highlighting that significant partnership activity has been observed in this market, with several stakeholders entering into strategic collaborations to support the ongoing product development and commercialization initiatives of such products. In the foreseen future, promising results from the ongoing clinical research initiatives are likely to bring in more investments to support product development activity in this upcoming market segment. Therefore, we are led to anticipate significant growth in this domain in the coming years.
Several recent developments have taken place in the field of non-hormonal therapies for women health. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.
The “Non-hormonal Therapies Market for Women’s Health by Target Indication (Bacterial Vaginosis, Contraception, Endometriosis, Postmenopausal Osteoporosis, Uterine Fibroids, Vaginitis and Others), Type of Molecule (Biologic and Small Molecule), Purpose of Therapy (Treatment of Disease and Management of Symptoms), Mechanism of Action (Antagonist, Agonist, Inhibitor and Modulator), Route of Administration (intramuscular, intravaginal, intravenous, oral, subcutaneous, topical, transdermal and others), and Key Geographical Regions (North America, Europe and Asia-Pacific): Industry Trends and Global Forecasts, 2021-2030”report features an extensive study of the current market landscape of non-hormonal therapies, primarily focusing on prescription drugs. The study also includes an elaborate discussion on the future potential of this evolving market. Amongst other elements, the report features:
One of the key objectives of the report was to estimate the existing market size and the future opportunity associated with non-hormonal therapies, over the next decade. Based on multiple parameters, such as target patient population, likely adoption rates and expected pricing, we have provided informed estimates on the evolution of the market for the period 2021-2030. The report also features the likely distribution of the current and forecasted opportunity across [A] target indication (bacterial vaginosis, contraception, endometriosis, postmenopausal osteoporosis, uterine fibroids, vaginitis and others), [B] type of molecule (biologic and small molecule), [C] route of administration (intramuscular, intravaginal, intravenous, oral, subcutaneous, topical, transdermal and others), [D] key geographical regions (North America, Europe and Asia-Pacific). In addition, the chapter presents indication specific value creation analysis. In order to account for future uncertainties and to add robustness to our model, we have provided three market forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry’s growth.
All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.
Contents
Chapter 2 is an executive summary of the key insights captured in our research. It offers a high-level view on the current state of the non-hormonal therapies for women’s health market and its likely evolution in the short to mid term and long term.
Chapter 3 provides a general overview of non-hormonal therapies, including a discussion on the key historical milestones in their development. It further includes an overview of the clinical conditions associated with women’s health. Furthermore, it outlines various available treatment modalities for women’s health related conditions (namely surgeries, hormonal therapies and non-hormonal therapies), with key focus on non-hormonal treatment options and prescription therapies. The chapter concludes with a discussion on the risks and benefits associated with non-hormonal therapies, along with demonstrating their future potential in the market.
Chapter 4 presents a detailed assessment of the current market landscape of non-hormonal therapies along with information on the industry players active in the domain of women’s health. In addition, it features an in-depth analysis of the pipeline molecules, based on a several relevant parameters, such as, current phase of development (marketed, clinical, preclinical and discovery), type of molecule (biologic and small molecule), target indication(bacterial vaginosis, contraception, endometriosis, postmenopausal osteoporosis, uterine fibroids, vaginitis and others), purpose of therapy (treatment of disease and management of symptoms), target women population (adult, postmenarchal and premenopausal female, postmenopausal female), mechanism of action (antagonists, agonists, inhibitors and modulators), route of administration (intramuscular, intravaginal, intravenous, oral, subcutaneous, topical, transdermal and others)and special drug designation(s) awarded (if any).
Chapter 5 provides a detailed review of the players engaged in the development of non-hormonal therapies, along with information on their year of establishment, company size, location of headquarters, and regional landscape.
Chapter 6 features an elaborate discussion on the various strategies that can be adopted by therapy developers engaged in this domain, across key commercialization stages, including prior to drug launch, during drug launch and post-launch. In addition, it presents an in-depth analysis of the key commercialization strategies that have been adopted by developers of non-hormonal therapies approved during the period 2017-2020.
Chapter 7 provides detailed profiles of phase III non-hormonal therapies. Each drug profile provides information on their current development status, route of administration, primary target indication, dosage, mechanism of action, clinical trials, clinical trial results, collaborations and special drug designation(s) received (if any).
Chapter 8 presents a detailed, geographical clinical trial analysis of completed and ongoing studies focused on non-hormonal therapies, based on several relevant parameters, such as trial registration year, trial status, trial phase, target indication, geography, type of sponsor, prominent treatment sites and enrolled patient population.
Chapter 9 features an elaborate analysis and discussion of the various collaborations and partnerships that have been inked amongst players engaged in the development of non-hormonal therapies, during the period pre2013 - 2020. It includes a brief description on the various types of partnership models including research agreements, research and development agreements, contract manufacturing agreements, licensing agreements and other relevant types of deals, that have been adopted by stakeholders in this domain. Furthermore, we have provided a world map representation of all the deals inked in this field, highlighting those that have been established within and across different continents. In addition, the chapter presents details on various funding instances, investments and grants reported within the non-hormonal therapy domain. The chapter includes information on various types of investments, such as seed financing, debt financing, grants, venture capital financing, and others, received by the companies between pre 2013 and 2020, highlighting the growing interest of the strategic investors in this market.
Chapter 10 presents an elaborate market forecast analysis, highlighting the future potential of the market till the year 2030. It also includes future sales projections of non-hormonal therapies that are either marketed or in advanced stage of clinical development (phase III). Sales potential and growth opportunity were estimated based on the target patient population, likely adoption rates, existing / future competition from other drug classes and the likely price of products. The chapter also presents a detailed market segmentation on the basis of [A] target indication (bacterial vaginosis, contraception, endometriosis, postmenopausal osteoporosis, uterine fibroids, vaginitis and others), [B] type of molecule (biologic and small molecule), [C] route of administration (intramuscular, intravaginal, intravenous, oral, subcutaneous, topical, transdermal and others), [D] key geographical regions (North America, Europe and Asia-Pacific). In addition, the chapter presents indication specific value creation analysis.
Chapter 11 summarizes the overall report, wherein we have mentioned all the key facts and figures described in the previous chapters. The chapter also highlights important evolutionary trends that were identified during the course of the study and are expected to influence the future of the non-hormonal therapy market.
Chapter 12 is an appendix, which provides tabulated data and numbers for all the figures provided in the report.
Chapter 13 is an appendix, which provides the list of companies mentioned in the report.
1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Women’s Health and Affiliated Clinical Conditions
3.2.1. Key Milestones in the Treatment of Women’s Health-related Disorders
3.3. Women’s Health-related Conditions
3.4. Available Treatment Modalities
3.4.1. Surgery
3.4.2. Hormonal Therapies
3.4.3. Non-Hormonal Therapies
3.5. Future Perspectives
4. MARKET OVERVIEW
4.1. Chapter Overview
4.2. Non-hormonal Therapies Market: Pipeline
4.2.1. Analysis by Phase of Development
4.2.2. Analysis by Type of Molecule
4.2.3. Analysis by Target Indication
4.2.4. Analysis by Phase of Development and Target Indication
4.2.5. Analysis by Type of Molecule and Target Indication
4.2.6. Analysis by Purpose of Therapy
4.2.7. Analysis by Target Women Population
4.2.8. Analysis by Mechanism of Action
4.2.9. Analysis by Route of Administration
4.3.1. Analysis by Special Designation(s) Awarded
5. COMPETITIVE LANDSCAPE
5.1. Chapter Overview
5.2. Non-hormonal Therapies Market: List of Developers
5.2.1. Analysis by Year of Establishment
5.2.2. Analysis by Company Size
5.2.3. Analysis by Geography
5.3. Key Players: Analysis by Number of Product Candidates
5.4. Big Pharma Initiatives
6. KEY COMMERCIALIZATION STRATEGIES
6.1. Chapter Overview
6.2. Successful Drug Launch Strategy: ROOTS Framework
6.3. Successful Drug Launch Strategy: Product Differentiation
6.4. Commonly Adopted Commercialization Strategies based on the Development Stage of the Product
6.5. Approved Non-hormonal Prescription Drugs
6.6. Key Commercialization Strategies Adopted by Companies Focused on Women’s Health
6.6.1. Strategies Adopted Before Therapy Approval
6.6.1.1. Participation in Global Events
6.6.1.2. Collaboration with Industry Stakeholders and Other Pharmaceutical Firms
6.6.1.3. Expansion of Target Indication
6.6.2. Strategies Adopted During / Post Therapy Approval
6.6.2.1. Geographical Expansion
6.6.2.2. Participation in Global Events
6.6.2.3. Patient Assistance Programs
6.6.2.4. Awareness Through Product Websites
6.6.2.5. Collaboration with Industry Stakeholders and Other Pharmaceutical Firms
6.6.2.6. Aligning with Government Initiatives to Ensure High Adoption Rate
6.7. Concluding Remarks
7. DRUG PROFILES (PHASE III)
7.1. Chapter Overview
7.2. Relugolix
7.3. DARE-BV1 (Clindamycin gel)
7.4. Ovaprene®
7.5. Yselty® (Linzagolix)
7.6. Fezolinetant
7.7. BAY1002670 (Vilaprisan)
7.8. Abaloparatide-TD
7.9. Terconazole (0.4%)
7.10. SCY-078 (Ibrexafungerp)
7.11. VT-1161 (Oteseconazole)
7.12. MV140 (Uromune)
7.13. Orilissa™ (Elagolix)
7.14. EVO100 (Amphora)
8. CLINICAL TRIAL ANALYSIS
8.1. Chapter Overview
8.2. Scope and Methodology
8.3. Non-hormonal Therapies: Clinical Trial Analysis
8.3.1. Analysis by Trial Registration Year
8.3.2. Analysis by Trial Status
8.3.3. Analysis by Trial Phase
8.3.4. Analysis by Trial Registration Year and Trial Status
8.3.5. Analysis by Target Patient Segment
8.3.6. Analysis by Target Indication
8.3.7. Analysis by Type of Sponsor
8.3.8. Analysis by Geography
8.3.8.1. Analysis by Geography (Pre-2017 and Post 2017)
8.4. Non-Hormonal Therapies: Analysis by Enrolled Patient Population
8.4.1. Analysis by Trial Registration Year
8.4.2. Analysis by Trial Status
8.4.3. Analysis by Trial Phase
8.4.4. Analysis by Geography
8.4.4.1. Analysis by Geography (Pre-2017 and Post 2017)
8.5. Analysis by Study Design
8.6. Concluding Remarks
8.6.1. Emerging Molecules to Watch
8.6.2. Most Important Trials to Watch
9. RECENT DEVELOPMENTS
9.1. Chapter Overview
9.2. Partnership Models
9.3. Non-hormonal Therapies: Recent Partnerships
9.3.1. Analysis by Year of Partnership
9.3.2. Analysis by Type of Partnership
9.3.3. Analysis by Target Indication
9.3.4. Most Active Players: Analysis by Number of Partnerships
9.3.5. Geographical Analysis
9.3.5.1. Intercontinental and Intracontinental Agreements
9.4. Types of Funding
9.5. Non-Hormonal Therapies: Funding and Investment Analysis
9.5.1. Analysis by Number of Funding Instances
9.5.2. Analysis by Amount Invested
9.5.3. Analysis by Type of Funding
9.5.4. Analysis by Type of Funding and Year
9.5.5. Analysis by Funding Amount and Year
9.5.6. Regional Analysis by Amount Invested
9.5.7. Most Active Players
9.6. Concluding Remarks
10. MARKET FORECAST AND OPPORTUNITY ANALYSIS
10.1. Chapter Overview
10.2. Scope and Limitations
10.3. Key Assumptions and Forecast Methodology
10.4. Global Non-hormonal Therapiesfor Women’s Health Market, 2021-2030
10.4.1. Non-hormonal Therapies Market: Analysis by Target Indication
10.4.2. Non-hormonal Therapies Market: Analysis by Type of Molecule
10.4.3. Non-hormonal Therapies Market: Analysis by Route of Administration
10.4.4. Non-hormonal Therapies Market: Analysis by Geography
10.5. Non-hormonal Therapies for Women’s Health Market: Value Creation Analysis
10.5.1. Bacterial Vaginosis
10.5.2. Contraception
10.5.3. Endometriosis
10.5.4. Postmenopausal Osteoporosis
10.5.5. Uterine Fibroids
10.5.6. Vasomotor Symptoms
10.6. Non-hormonal Therapies for Women’s Health Market: Product Wise Sales Forecasts
10.6.1. Nuvessa (Metronidazole)
10.6.1.1. Target Patient Population
10.6.1.2. Sales Forecast
10.6.1.3. Net Present Value
10.6.2. VivaGel (SPL 7013)
10.6.2.1. Target Patient Population
10.6.2.2. Sales Forecast
10.6.2.3. Net Present Value
10.6.3. Solosec (Secnidazole)
10.6.3.1. Target Patient Population
10.6.3.2. Sales Forecast
10.6.3.3. Net Present Value
10.6.4. Tymlos (Abaloparatide)
10.6.4.1. Target Patient Population
10.6.4.2. Sales Forecast
10.6.4.3. Net Present Value
10.6.5. Orilissa
10.6.5.1. Target Patient Population
10.6.5.2. Sales Forecast (Endometriosis)
10.6.5.3. Sales Forecast (Uterine Fibroids)
10.6.5.4. Net Present Value
10.6.6. Osphena (Ospemifene)
10.6.6.1. Target Patient Population
10.6.6.2. Sales Forecast
10.6.6.3. Net Present Value
10.6.7. Evenity(Romosozumab-aqqg)
10.6.7.1. Target Patient Population
10.6.7.2. Sales Forecast
10.6.7.3. Net Present Value
10.6.8. Esmya and Fibristal (Ulipristal acetate)
10.6.8.1. Target Patient Population
10.6.8.2. Sales Forecast
10.6.8.3. Net Present Value
10.6.9. Phexxi (Amphora)
10.6.9.1. Target Patient Population
10.6.9.2. Sales Forecast
10.6.9.3. Net Present Value
10.6.10. Oriahnn
10.6.10.1. Target Patient Population
10.6.10.2. Sales Forecast
10.6.10.3. Net Present Value
10.6.11. Relugolix
10.6.11.1. Target Patient Population
10.6.11.2. Sales Forecast (Uterine Fibroids)
10.6.11.3. Sales Forecast (Endometriosis)
10.6.11.4. Net Present Value
10.6.12. DARE-BV1 (Clindamycin gel)
10.6.12.1. Target Patient Population
10.6.12.2. Sales Forecast
10.6.12.3. Net Present Value
10.6.13. Ovaprene
10.6.13.1. Target Patient Population
10.6.13.2. Sales Forecast
10.6.13.3. Net Present Value
10.6.14. Yselty (Linzagolix)
10.6.14.1. Target Patient Population
10.6.14.2. Sales Forecast (Endometriosis)
10.6014.3. Sales Forecast (Uterine Fibroids)
10.6.14.3. Net Present Value
10.6.15. Fezolinetant
10.6.15.1. Target Patient Population
10.6.15.2. Sales Forecast
10.6.15.3. Net Present Value
10.6.16. BAY1002670 (Vilaprisan)
10.6.16.1. Target Patient Population
10.6.16.2. Sales Forecast
10.6.16.3. Net Present Value
10.6.17. Abaloparatide-TD
10.6.17.1. Target Patient Population
10.6.17.2. Sales Forecast
10.6.17.3. Net Present Value
10.6.18. Terconazole(0.4%)
10.6.18.1. Target Patient Population
10.6.18.2. Sales Forecast
10.6.18.3. Net Present Value
10.6.19. SCY-078 (Ibrexafungerp)
10.6.19.1. Target Patient Population
10.6.19.2. Sales Forecast
10.6.19.3. Net Present Value
10.6.20. VT-1161 (Oteseconazole)
10.6.20.1. Target Patient Population
10.6.20.2. Sales Forecast
10.6.20.3. Net Present Value
10.6.21. MV140 (Uromune)
10.6.21.1. Target Patient Population
10.6.21.2. Sales Forecast
10.6.21.3. Net Present Value
10.6.22. EVO100
10.6.22.1. Target Patient Population
10.6.22.2. Sales Forecast
10.6.22.3. Net Present Value
11. CONCLUDING REMARKS
12. APPENDIX 1: TABULATED DATA
13. APPENDIX 2: LIST OF COMPANIES
Figure 3.1 Key Milestones in the Treatment of Women’s Health-related Disorders
Figure 3.2 Women’s Health-related Conditions
Figure 3.3 Available Treatment Modalities: Non-hormonal Therapies
Figure 4.1 Non-hormonal Therapies: Distribution by Phase of Development
Figure 4.2 Non-hormonal Therapies: Distribution by Type of Molecule
Figure 4.3 Non-hormonal Therapies: Distribution by Target Indication
Figure 4.4 Non-hormonal Therapies: Distribution by Phase of Development and Target Indication
Figure 4.5 Non-hormonal Therapies: Distribution by Type of Molecule and Target Indication
Figure 4.6 Non-hormonal Therapies: Distribution by Purpose of Therapy
Figure 4.7 Non-hormonal Therapies: Distribution by Target Women Population
Figure 4.8 Non-hormonal Therapies: Distribution by Mechanism of Action
Figure 4.9 Non-hormonal Therapies: Distribution by Route of Administration
Figure 4.10 Non-hormonal Therapies: Distribution by Special Designation(s) Awarded
Figure 5.1 Non-hormonal Therapy Developers: Distribution by Year of Establishment
Figure 5.2 Non-hormonal Therapy Developers: Distribution by Company Size
Figure 5.3 Non-hormonal Therapy Developers: Distribution by Location of Headquarters
Figure 5.4 Non-hormonal Therapy Developers: Distribution by Year of Establishment, Company Size and Location of Headquarters
Figure 5.5 Non-hormonal Therapy Developers: Big Pharma Initiatives
Figure 6.1 Successful Drug Launch Strategy: ROOTS Framework
Figure 6.2 Successful Drug Launch Strategy: Product Differentiation
Figure 6.3 Commonly Adopted Commercialization Strategies based on Development Stage of the Product
Figure 6.4 Harvey Ball Analysis: Commercialization Strategies Adopted by Companies Focused on Women’s Health
Figure 6.5 Approved Non-hormonal Prescription Drugs: Snapshot of Promotional Activities on Product Websites
Figure 6.6 Key Commercialization Strategies: Harvey Ball Analysis by Ease of Implementation, Value Addition and Current Adoption
Figure 8.1 Clinical Trial Analysis: Cumulative Distribution by Trial Registration Year, Pre 2013-2020
Figure 8.2 Clinical Trial Analysis: Distribution by Trial Status
Figure 8.3 Clinical Trial Analysis: Distribution by Trial Phase
Figure 8.4 Clinical Trial Analysis: Distribution by Trial Registration Year and Trial Status
Figure 8.5 Clinical Trial Analysis: Distribution by Target Patient Segment
Figure 8.6 Clinical Trial Analysis: Distribution by Target Indication
Figure 8.7 Clinical Trial Analysis: Distribution by Type of Sponsor
Figure 8.8 Clinical Trial Analysis: Distribution by Geography
Figure 8.9 Clinical Trial Analysis: Distribution by Geography,Pre-2017 and Post-2017
Figure 8.10 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Registration Year
Figure 8.11 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Status
Figure 8.12 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Phase
Figure 8.13 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Location of Trial Site
Figure 8.14 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Geography, Pre-2017 and Post 2017
Figure 8.15 Clinical Trial Analysis: Distribution by Study Design
Figure 9.1 Partnerships and Collaborations: Cumulative Year-wise Trend, 2013-2021
Figure 9.2 Partnerships and Collaborations: Distribution by Type of Partnership
Figure 9.3 Partnerships and Collaborations: Cumulative Trend by Year and Type of Collaboration, 2013-2021
Figure 9.4 Partnerships and Collaborations: Distribution by Type of Merger / Acquisition
Figure 9.5 Partnerships and Collaborations: Distribution by Focus Area
Figure 9.6 Partnerships and Collaborations: Distribution by Target Indication
Figure 9.7 Most Active Players: Distribution by Number of Partnerships
Figure 9.8 Partnerships and Collaborations: Intercontinental and Intracontinental Distribution
Figure 9.9 Funding and Investment Analysis: Cumulative Year-wise Distribution by Number of Instances, 2016-2020
Figure 9.10 Funding and Investment Analysis: Cumulative Year-wise Distribution of Amount Invested, 2016-2020 (USD Million)
Figure 9.11 Funding and Investment Analysis: Distribution by Type of Funding
Figure 9.12 Funding and Investment Analysis: Distribution by Year and Type of Funding
Figure 9.13 Funding and Investment Analysis: Distribution by Year and Funding Amount (USD Million)
Figure 9.14 Funding and Investment Analysis: Summary of Investments, 2016-2020 (USD Million)
Figure 9.15 Funding and Investment Analysis: Distribution by Geography
Figure 9.16 Funding and Investment Analysis: Regional Distribution of Funding Instances
Figure 9.17 Most Active Players: Distribution by Number of Funding Instances, 2016-2020
Figure 9.18 Most Active Players: Distribution by Amount Invested, 2016-2020 (USD Million)
Figure 9.19 Funding and Investment Summary, 2016-2020 (USD Million)
Figure 10.1 Global Non-hormonal Therapies for Women’s Health Market, 2021-2030: Base Case Scenario (USD Million)
Figure 10.2 Non-hormonal Therapies Market: Distribution by Target Indication, 2021, 2025 and 2030
Figure 10.3 Non-hormonal Therapies Market: Distribution by Type of Molecule, 2021, 2025 and 2030
Figure 10.4 Non-hormonal Therapies Market: Distribution by Route of Administration, 2021, 2025 and 2030
Figure 10.5 Non-hormonal Therapies Market: Distribution by Geography, 2021, 2025 and 2030
Figure 10.6 Nuvessa Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.7 VivaGel Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.8 Solosec Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.9 Tymlos Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.10 Orilissa (Endometriosis) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.11 Orilissa (Uterine Fibroids) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.12 Osphena Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.13 Evenity Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.14 Esmya and Fibristal Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.15 Phexxi Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.16 Oriahnn Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.17 Relugolix (Uterine Fibroids) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.18 Relugolix (Endometriosis) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.19 DARE-BV1 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.20 Ovaprene Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.21 Yselty (Endometriosis) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.22 Yselty (Uterine Fibroids) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.23 Fezolinetant Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.24 BAY1002670 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.25 Abaloparatide-TD Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.26 Terconazole (0.4%) Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.27 SCY-078 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.28 VT-1161 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.29 MV140 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 10.30 EVO100 Sales Forecast (Till 2030): Base Scenario (USD Million)
Figure 11.1 Concluding Remarks: Summary of the Current Market Landscape
Figure 11.2 Concluding Remarks: Summary of the Current Developer Landscape
Figure 11.3 Concluding Remarks: Summary of Recent Developments
Figure 11.4 Concluding Remarks: Market Sizing and Opportunity Analysis
Table 3.1 Women’s Health-related Conditions: Menopause
Table 3.2 Available Treatment Modalities: Surgeries
Table 3.3 Available Treatment Modalities: Hormonal Therapies
Table 4.1 Non-hormonal Therapies Market: Development Pipeline
Table 5.1 Non-hormonal Therapies Market: List of Developers
Table 6.1 Solosec™: Presentations in Conferences Before Product Approval
Table 6.2 Orilissa™: Presentations in Conferences Before Product Approval
Table 6.3 Evenity™: Presentations in Conferences Before Product Approval
Table 6.4 Phexxi™: Presentations in Conferences Before Product Approval
Table 6.5 Oriahnn™: Presentations in Conferences Before Product Approval
Table 6.6 Tymlos™: Presentations in Conferences After Product Approval
Table 6.7 Phexxi™: Presentations in Conferences After Product Approval
Table 6.8 Approved Non-hormonal Therapies: Comparison of Patient Support Services Available on Product Websites
Table 7.1 Non-hormonal Therapy Market: List of Phase III Products
Table 7.2 Drug Profile: Relugolix (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.3 Drug Profile: DARE-BV1 (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.4 Drug Profile: Ovaprene® (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.5 Drug Profile: Yselty® (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.6 Drug Profile: Fezolinetant (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.7 Drug Profile: BAY1002670 (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.8 Drug Profile: Abaloparatide-TD (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.9 Drug Profile: Terconazole (0.4%) (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.10 Drug Profile: SCY-078(Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.11 Drug Profile: VT-1161(Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.12 Drug Profile: MV140 (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.13 Drug Profile: Orilissa (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 7.14 Drug Profile: EVO100 (Overview of Drug, Current Development Status and Clinical Trial Results)
Table 8.1 Clinical Trial Analysis: Emerging Molecules
Table 8.2 Clinical Trial Analysis: Prominent Ongoing Studies
Table 9.1 Non-hormonal Therapy Market: List of Partnerships and Collaborations, Pre 2013-2021
Table 9.2 Non-hormonal Therapy Market: List of Funding and Investments, 2016-2020
Table 10.1 Non-hormonal Therapies: Expected Launch Years of Advanced Stage Drug Candidates
Table 10.2 Nuvessa: Target Patient Population
Table 10.3 Nuvessa: Net Present Value (USD Million)
Table 10.4 VivaGel: Target Patient Population
Table 10.5 VivaGel: Net Present Value (USD Million)
Table 10.6 Solosec: Target Patient Population
Table 10.7 Solosec: Net Present Value (USD Million)
Table 10.8 Tymlos: Target Patient Population
Table 10.9 Tymlos: Net Present Value (USD Million)
Table 10.10 Orilissa: Target Patient Population
Table 10.11 Orilissa: Net Present Value (USD Million)
Table 10.12 Osphena: Target Patient Population
Table 10.13 Osphena: Net Present Value (USD Million)
Table 10.14 Evenity: Target Patient Population
Table 10.15 Evenity: Net Present Value (USD Million)
Table 10.16 Esmya and Fibristal: Target Patient Population
Table 10.17 Esmya and Fibristal: Net Present Value (USD Million)
Table 10.18 Phexxi: Target Patient Population
Table 10.19 Phexxi: Net Present Value (USD Million)
Table 10.20 Oriahnn: Target Patient Population
Table 10.21 Oriahnn: Net Present Value (USD Million)
Table 10.22 Relugolix: Target Patient Population
Table 10.23 Relugolix: Net Present Value (USD Million)
Table 10.24 DARE-BV1: Target Patient Population
Table 10.25 DARE-BV1: Net Present Value (USD Million)
Table 10.26 Ovaprene: Target Patient Population
Table 10.27 Ovaprene: Net Present Value (USD Million)
Table 10.28 Yselty: Target Patient Population
Table 10.29 Yselty: Net Present Value (USD Million)
Table 10.30 Fezolinetant: Target Patient Population
Table 10.31 Fezolinetant: Net Present Value (USD Million)
Table 10.32 BAY1002670: Target Patient Population
Table 10.33 BAY1002670: Net Present Value (USD Million)
Table 10.34 Abaloparatide-TD: Target Patient Population
Table 10.35 Abaloparatide-TD: Net Present Value (USD Million)
Table 10.36 Terconazole (0.4%): Target Patient Population
Table 10.37 Terconazole (0.4%): Net Present Value (USD Million)
Table 10.38 SCY-078: Target Patient Population
Table 10.39 SCY-078: Net Present Value (USD Million)
Table 10.40 VT-1161: Target Patient Population
Table 10.41 VT-1161: Net Present Value (USD Million)
Table 10.42 MV140: Target Patient Population
Table 10.43 MV140: Net Present Value (USD Million)
Table 10.44 EVO100: Target Patient Population
Table 10.45 EVO100: Net Present Value (USD Million)
Table 13.1 Non-hormonal Therapies: Distribution by Phase of Development
Table 13.2 Non-hormonal Therapies: Distribution by Type of Molecule
Table 13.3 Non-hormonal Therapies: Distribution by Target Indication
Table 13.4 Non-hormonal Therapies: Distribution by Phase of Development and Target Indication
Table 13.5 Non-hormonal Therapies: Distribution by Type of Molecule and Target Indication
Table 13.6 Non-hormonal Therapies: Distribution by Purpose of Therapy
Table 13.7 Non-hormonal Therapies: Distribution by Target Women Population
Table 13.8 Non-hormonal Therapies: Distribution by Mechanism of Action
Table 13.9 Non-hormonal Therapies: Distribution by Route of Administration
Table 13.10 Non-hormonal Therapies: Distribution by Special Designation(s) Awarded
Table 13.11 Non-hormonal Therapy Developers: Distribution by Year of Establishment
Table 13.12 Non-hormonal Therapy Developers: Distribution by Company Size
Table 13.13 Non-hormonal Therapy Developers: Distribution by Location of Headquarters
Table 13.14 Non-hormonal Therapy Developers: Distribution by Year of Establishment, Company Size and Location of Headquarters
Table 13.15 Non-hormonal Therapy Developers: Big Pharma Initiatives
Table 13.16 Clinical Trial Analysis: Cumulative Distribution by Trial Registration Year, Pre 2013-2020
Table 13.17 Clinical Trial Analysis: Distribution by Trial Status
Table 13.18 Clinical Trial Analysis: Distribution by Trial Phase
Table 13.19 Clinical Trial Analysis: Distribution by Trial Registration Year and Trial Status
Table 13.20 Clinical Trial Analysis: Distribution by Target Patient Segment
Table 13.21 Clinical Trial Analysis: Distribution by Target Indication
Table 13.22 Clinical Trial Analysis: Distribution by Type of Sponsor
Table 13.23 Clinical Trial Analysis: Distribution by Geography
Table 13.24 Clinical Trial Analysis: Distribution by Geography, Pre-2017 and Post 2017
Table 13.25 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Registration Year
Table 13.26 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Status
Table 13.27 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Trial Phase
Table 13.28 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Location of Trial Site
Table 13.29 Clinical Trial Analysis: Distribution of Enrolled Patient Population by Geography , Pre-2017 and Post 2017
Table 13.30 Clinical Trial Analysis: Distribution by Study Design
Table 13.31 Partnerships and Collaborations: Cumulative Trend by Year, 2013-2021
Table 13.32 Partnerships and Collaborations: Distribution by Type of Partnership
Table 13.33 Partnerships and Collaborations: Cumulative Trend by Year and Type of Collaboration, 2013-2021
Table 13.34 Partnerships and Collaborations: Distribution by Type of Acquisition / Merger
Table 13.35 Partnerships and Collaborations: Distribution by Focus Area
Table 13.36 Partnerships and Collaborations: Distribution by Target Indication
Table 13.37 Most Active Players: Distribution by Number of Partnerships
Table 13.38 Partnerships and Collaborations: Intercontinental and Intracontinental Distribution
Table 13.39 Funding and Investment Analysis: Cumulative Year-wise Distribution by Number of Instances, 2016-2020
Table 13.40 Funding and Investment Analysis: Cumulative Year-wise Distribution of Amount Invested, 2016-2020 (USD Million)
Table 13.41 Funding and Investment Analysis: Distribution by Type of Funding
Table 13.42 Funding and Investment Analysis: Distribution by Year and Type of Funding
Table 13.43 Funding and Investment Analysis: Distribution by Year and Funding Amount (USD Million)
Table 13.44 Funding and Investment Analysis: Distribution by Geography
Table 13.45 Funding and Investment Analysis: Regional Distribution of Funding Instances
Table 13.46 Most Active Players: Distribution by Number of Funding Instances, 2016-2020
Table 13.47 Most Active Players: Distribution by Amount Invested, 2016-2020 (USD Million)
Table 13.48 Funding and Investment Summary, 2016-2020 (USD Million)
Table 13.49 Global Non-hormonal Therapies for Women’s Health Market, 2021-2030: Base Case Scenario (USD Million)
Table 13.50 Non-hormonal Therapies Market: Distribution by Target Indication, 2021, 2025 and 2030
Table 13.51 Non-hormonal Therapies Market: Distribution by Type of Molecule, 2021, 2025 and 2030
Table 13.52 Non-hormonal Therapies Market: Distribution by Route of Administration, 2021, 2025 and 2030
Table 13.53 Non-hormonal Therapies Market: Distribution by Geography, 2021, 2025 and 2030
Table 13.54 Nuvessa Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.55 VivaGel Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.56 Solosec Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.57 Tymlos Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.58 Orilissa (Endometriosis) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.59 Orilissa (Uterine Fibroids) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.60 Osphena Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.61 Evenity Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.62 Esmya and Fibristal Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.63 Phexxi Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.64 Oriahnn Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.65 Relugolix (Uterine Fibroids) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.66 Relugolix (Endomteriosis) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.67 DARE-BV1 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.68 Ovaprene Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.69 Yselty (Endometriosis) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.70 Yselty (Uterine Fibroids) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.71 Fezolinetant Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.72 BAY1002670 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.73 Abaloparatide-TD Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.74 Terconazole (0.4%) Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.75 SCY-078 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.76 VT-1161 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.77 MV140 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
Table 13.78 EVO100 Sales Forecast (Till 2030): Conservative, Base and Optimistic Scenarios (USD Million)
The following companies / institutes / government bodies and organizations have been mentioned in this report.
Source 1: www.who.int/news-room/commentaries/detail/ten-top-issues-for-women's-health
Source 2: www.webmd.com/menopause/news/20130701/health-highlights-july-1-2013