RNA Therapeutics Market

RNA Therapeutics Market and RNA Vaccines Market by Type of Modality, Type of Molecule, Therapeutic Areas, Route of Administration, Key Geographical Regions (North America, Europe and Asia-Pacific) and Leading Players: Industry Trends and Global Forecasts, 2023-2035

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The image provides context of RNA therapeutics market. Owing to their clinical potential to specifically target and treat various disease indications, the next generation RNA therapeutics and vaccines have gained significant traction and are anticipated to revolutionize the healthcare and medical sector This image provides a list of next generation RNA Therapeutics and RNA Vaccines. More than 100 next generation RNA therapeutics and vaccines are being developed to offer an advanced, low-dose form of treatment, targeting a wide range of therapeutic indications The infographic looks at the RNA therapeutics market distribution. 75% of the next generation therapies are still in discovery and preclinical stages, primarily targeting infectious diseases; industry players are actively engaged in advancing their next generation drug portfolio 
The image provides a list of next generation RNA technologies. Over 35 next generation RNA technologies are being developed / offered by companies for the research, discovery, design, development, manufacturing and delivery of novel RNA therapies and vaccines
The image looks at the next generation RNA technologies market landscape. Around 55% of the technologies are used in the development of circular RNA-based therapeutics and vaccines; majority of such technologies facilitate targeted therapy delivery at a specific site within the cell
This image looks at the clinical trial analysis of RNA therapeutics. Majority of the trials focused on RNA therapeutics and vaccines were registered in 2022; more than 70% of these studies have either been completed / are currently recruiting patients across different locations The snapshot looks at the patent analysis within RNA therapeutics market. Close to 1,170 patents have been filed / granted for next generation RNA therapeutics and vaccines, by industry and non-industry players, to protect intellectual property generated within this field This image provides details on various partnerships that have been inked in the field of RNA therapy. Around 70% of the deals inked in this market were focused on clinical research of saRNA therapeutics / vaccines; of these, more than 60% partnerships were inked for the treatment of infectious diseases
The image highlights the level of interest shown by investors in RNA therapy market. Several investors, having realized the opportunity within this domain, have invested close to USD 2.9 Billion across various funding rounds in the past four years The infographic looks at the interested being shown by big pharma in development of RNA therpaeutics. The rising interest of big pharma players is reflected by the increase in the number of next generation RNA therapeutics / vaccines-focused initiatives, including partnerships and funding, undertaken in recent years This image looks at the RNA therapeutics and RNA vaccines market size. The market opportunity associated with next generation RNA therapeutics and vaccines is expected to witness an annualized growth rate of more than 50% between 2026 to 2035
The infographic provides a view on the market segmentation within RNA therapeutics and RNA vaccines market. The estimated market opportunity is expected to be well distributed across various routes of administration, geographical regions and leading players

Report Description

RNA Therapeutics and RNA Vaccines Market Overview

The global RNA Vaccines and RNA Therapeutics market is estimated to be worth over USD 1.1 billion in 2035 and is expected to grow at compounded annual growth rate (CAGR) of 50% during the forecast period (2026-2035). In the past few years, RNA based therapeutics have emerged as one of the key therapeutic modalities in the modern healthcare industry. These RNA based therapeutics play a crucial role in protein production and regulation of gene functions. In addition, they offer enhanced therapeutic and safety profiles as compared to traditional treatment approaches. However, there are some concerns associated with the highly unstable nature of such molecules and their delivery at adequate concentrations. Therefore, in order to address the challenges pertaining to the use of RNA therapeutics and RNA vaccines, several industry players have been engaged in the development / deployment of novel technologies for the design, development and manufacturing of next generation RNA-based therapeutics / vaccines, offering the healthcare sector a promising disease management recourse.

The next generation RNA therapeutics and RNA vaccines are modified treatment molecules aimed at specifically targeting and treating diseases that were earlier considered undruggable. Among these, innovative modalities, such as circular RNA (circRNA), endless RNA (eRNA), self activating RNA (sacRNA), self amplifying RNA (saRNA), self amplifying mRNA (samRNA), replicating RNA (repRNA) and transfer RNA (tRNA) have emerged as popular targeted therapeutics. The success of these next generation RNA therapeutics and RNA vaccines can be attributed to their structural stability, expression specificity, targeted delivery, non-immunogenic nature, high efficiency and ability to target a wide range of therapeutic modalities, including influenza, COVID-19 infection, breast cancer and interstitial lung disease, among others. Further, owing to their self-replicating nature, such RNA based therapeutics offer prolonged therapeutic effects at relatively low and less frequent doses, as compared to traditional methods.

Given the ongoing pace of innovation in this field, encouraging clinical trial results, accelerated approvals, and the continuous efforts of both industry and non-industry players, the next generation RNA vaccines and RNA therapeutics market is likely to witness significant growth during the forecast period.

Key Market Insights

The RNA Vaccines and RNA Therapeutics Market: Distribution by Type of Modality (RNA Therapeutics and RNA Vaccines), Type of Molecule (replicating RNA, self amplifying RNA, self activating RNA, self amplifying mRNA and transfer RNA), Therapeutic Areas (Infectious Diseases, Oncological Disorders and Pulmonary Disorders), Route of Administration (Intradermal, Intramuscular and Intravenous), Key Geographical Regions (North America, Europe and Asia-Pacific) and Leading Players: Industry Trends and Global Forecasts, 2023-2035 report features an extensive study of the current market landscape, market size and future opportunities associated with the RNA vaccines and RNA therapeutics market, during the given forecast period. Further, the market report highlights the efforts of several stakeholders engaged in this rapidly emerging segment of the pharmaceutical industry. Key takeaways of the RNA vaccines and RNA therapeutics market are briefly discussed below. 

Current Market Landscape: Next Generation RNA Therapeutics and RNA Vaccines Offering Efficient Treatment Recourse

The next generation RNA vaccines and RNA therapeutics market landscape is concentrated with the presence of over 35 large, mid-sized and small companies. Of these, 50% of the companies were established during the period 2016-2020, indicating significant start-up activity in this therapeutic market segment. Examples of companies (established in 2019 and 2020, in alphabetical order) include Chimerna Therapeutics, Orna Therapeutics, Replicate Bioscience, Transine Therapeutics, VaxEquity, VLP Therapeutics and Ziphius Vaccines. Further, more than 70% of the companies are based in North America. Within Europe, the UK has emerged as the hub of players engaged in the development of next generation RNA therapeutics and RNA vaccines.

It is worth mentioning that, currently, over 100 next generation RNA therapeutics and RNA vaccines are either approved or being evaluated in various stages of development; of these, nearly 25% of the drug candidates are being evaluated in clinical trials. Further, 40% and 32% of the drug candidates are being investigated for the treatment of infectious diseases and oncological disorders, respectively, across different phases of development. These drug candidates have emerged as popular targeted therapy among therapy developers.   

Recent advancements in the healthcare industry in the last few years have led to the development of various novel drug modalities. Interestingly, the industry is evaluating next generation RNA therapeutics and RNA vaccines, which have surfaced as possible targeted therapies for a wide range of therapeutic indications.

Clinical Trials Analysis: A number of RNA Therapeutics and RNA Vaccines are Being Evaluated in Clinical Trials

It is important to highlight that a therapeutic modality, ATYR1923, developed by aTyr Pharma, is currently being investigated in phase III, targeting Pulmonary Sarcoidosis. Recently, in August 2022, the drug received fast track designation from the USFDA. Over 1,160 clinical trial initiatives focused on various next generation drug modalities, such as circular RNA (circRNA), endless RNA (eRNA), self-activating RNA (sacRNA), self amplifying RNA (saRNA), self amplifying mRNA (samRNA), replicating RNA (repRNA) and transfer RNA (tRNA), long non coding RNA and others have been undertaken since 2019, indicating the substantial research efforts being made in this industry. 

Since 2021, 18 clinical trials have been registered for the evaluation of next generation RNA therapeutics and vaccines. Of these, 72% of the trials were focused on infectious diseases. This can be attributed to the enhanced activity of industry players towards the development of therapies targeting COVID-19. Interestingly, 27% of these trials have advanced to the late stages of development (phase II and above). As the next generation RNA therapeutics and RNA vaccines move along the clinical development trajectory, we expect the market to grow at a favorable CAGR during the forecast period. 

Self Amplifying mRNA Vaccines Offer Several Advantages Over the First Generation mRNA Vaccines

RNA vaccines have caught the attention of the pharmaceutical industry, specifically during the COVID-19 pandemic, when the first generation mRNA based COVID vaccine received approval from regulatory authorities. Prior to mRNA vaccines, other modalities, such as antisense RNA, siRNA and RNA aptamers were evaluated as therapeutics. Gemcovac®, developed by HDT Bio was the first self amplifying mRNA (saRNA) based COVID vaccine to receive emergency use approval in India, in June 2022. Notably, this COVID vaccine is currently being evaluated in clinical trials in the US, Brazil and South Korea. According to the pivotal trial results, Gemcovac® demonstrated a much lower rate of adverse events as compared to the COVID vaccine, developed by Moderna and Pfizer. The immunological response of the therapy was comparable to that developed by AstraZeneca. Additionally, Gemcovac® is supplied in lyophilized powder form and requires storage in a normal refrigerator. This self amplifying mRNA vaccine is delivered intradermally, unlike most of the COVID vaccines that are administered intramuscularly. Owing to their highly stable structure, enhanced therapeutic profile and low concentration administration, the next generation RNA therapeutics and RNA vaccines have emerged as a potential alternative to conventional RNA-based approaches.

Another player, Arcturus Therapeutics is developing the COVID vaccine using its proprietary self amplifying mRNA technology platform. In April 2023, its collaboration partner, Meiji Seika Pharma, submitted an NDA to commercialize the vaccine, ARCT-154, in Japan. The launch of more such self amplifying mRNA vaccines will drive the market growth over the forecast period.

Potential of tRNA Therapeutics is Being Explored by Few Key Companies

The pandemic offered a major thrust to RNA-based therapies. Since then, industry stakeholders are actively being engaged in the development of therapies that are long lasting and can target a wide range of therapeutic targets, giving rise to the development of next generation RNA therapeutics and RNA vaccines using various approaches.

One such approach involves the use of transfer RNA (tRNA), being engineered by US-based Alltrna, in order to correct gene code and ultimately gene expression. The company raised USD 50 million in Series A funding in 2020. However, Alltrna is not the sole company working on tRNA technology. Other companies include ReCode Therapeutics, ShapeTX, Tevard Biosciences and hC Bioscience. The current tRNA market landscape features the presence of close to ten therapies, of which, majority are still in early stages of development. These therapies are primarily being developed to target indications, such as Cystic Fibrosis, Duchenne Muscular Dystrophy and Pulmonary Sarcoidosis.

Circular RNA Therapeutics Market is Witnessing a number of Start Ups and Funding Activity

Circular RNA is a covalently bonded closed-loop RNA structure, engineered from linear RNAs by circularization. These structures confer higher stability to the RNA molecules, protecting the molecule from rapid degradation by exonucleases. Recently, the next generation RNA therapeutics and vaccines domain has witnessed the emergence of industry players engaged in the development of circular RNA therapies, owing to the vast potential and high stability of such therapies. Examples of some players include (in alphabetical order) Chimerna Therapeutics, Esperovax, Flagship Pioneering’s Laronde, Ginkgo Bioworks, Orna Therapeutics, Ring Code Biotech, Circio and Therorna. Notably, since 2019, more than USD 380 million has been raised / invested by companies engaged in the development of circular RNA, reflecting significant funding activity for circular RNA-based therapies in this domain.

It is worth highlighting that industry players are actively collaborating with circular RNA therapy developers in order to support the discovery, development and delivery of circRNA molecules. For instance, Renagade Therapeutics has entered into a collaboration with Orna Therapeutics in order to support the delivery of circular RNA therapies being discovered by Orna Therapeutics. Considering the potential of these therapies, several industry stakeholders are actively engaging in the development of such therapeutics. The support from venture capitalists and big pharmaceutical companies will continue to drive the development of circular RNA therapeutics and market growth over the forecast period.

Key Trends in the Next Generation RNA Therapeutics and RNA Vaccines Market

Many stakeholders are undertaking initiatives to forge alliances with other industry / non-industry players. Of the strategic partnerships focused on next generation RNA therapeutics and RNA vaccines that have been inked since 2019, close to 22% of partnerships are research and development agreements, indicating that the stakeholders are actively engaged in research and development of these next generation RNA therapeutics and RNA vaccines. Interestingly, it was observed that many big pharma players, such as Merck, Gilead Sciences, AstraZeneca and others have partnered with several next generation RNA therapeutics and RNA vaccines players, in order to expand their respective portfolios. It is worth highlighting that a sum of $2.9 billion has been raised / invested by players engaged in the development of RNA therapeutics and RNA vaccines, indicating the interest of stakeholders in this market.

Given the inclination towards development of novel next generation RNA therapeutics and RNA vaccines, along with the engagement of big pharma players and high investments, we believe that the next generation RNA therapeutics and RNA vaccines market is likely to evolve at a rapid pace over the forecast period. 

Next Generation RNA Vaccines and RNA Therapeutics Market Size: North America to Hold the Largest Market Share

Driven by the rising interest in R&D activities and growing demand for effective therapies for rare and oncological disorders, the next generation RNA therapeutics and RNA vaccines market is anticipated to witness an annualized growth rate (CAGR) of over 50%, during the forecast period (2026-2035). Specifically, in terms of type of molecule, the global market for next generation RNA therapeutics and RNA vaccines is anticipated to be driven by self amplifying mRNAs. Likewise, in terms of therapeutic area, the market is anticipated to be dominated by the RNA therapeutics and RNA vaccines targeting oncological disorders and pulmonary disorders.

In addition, close to 94% of the market share in 2035 is captured by the players based in North America. However, it is worth highlighting that the next generation RNA therapeutics and RNA vaccines market in Asia-Pacific is anticipated to grow at a higher CAGR, during the forecast period (2030-2035). 

Recently, the increasing number of orphan and fast track designations granted by the regulatory authorities, such as the USFDA and the EMA, has intrigued interest and increased the confidence of the pharmaceutical industry in these novel targeted therapies. All the above factors will contribute to a healthy market growth of the next generation RNA therapeutics and RNA vaccines market during the forecast period.

Leading Next Generation RNA Therapeutics and RNA Vaccines Developers

Examples of key companies engaged in the next generation RNA therapeutics and RNA vaccines development (which have also been captured in this market report, arranged in alphabetical order) include Alphavax, Arcturus Therapeutics, Atyr Pharma, Flagship Pioneering, Forge Therapeutics, Gingko Bioworks, Gritstone Bio, HDT Bio, Laronde Therapeutics, MiNA Therapeutics, Orna Therapeutics, Recode Therapeutics, Renegade Therapeutics, Replicate Bioscience, Shape Therapeutics and VLP Therapeutics. This market report includes an easily searchable excel database of all the companies developing next generation RNA therapeutics and RNA vaccines, worldwide.

Recent Developments in the Next Generation RNA Vaccines and RNA Therapeutics  Market

Several recent developments have taken place in the field of next generation RNA vaccines and RNA therapeutics, some of which have been outlined below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that we’ve outlined in our analysis.

  • In February 2023, Tevard Biosciences entered into a research and development agreement with Vertex Pharmaceuticals for the development of novel tRNA based therapies, intended for the treatment of Duchenne Muscular Dystrophy.
  • In January 2023, Esperovax entered into a product development agreement with Gingko Bioworks for the development of circular RNA therapeutics, specifically targeting colorectal cancer.
  • Further, in January 2023, HDT Bio entered into a technology utilization agreement with the Pan African Cancer Research Institute (PACRI), in order to develop self-amplifying RNA vaccines and therapeutics.

Scope of the Report

The market report presents an in-depth analysis of the various firms / organizations that are engaged in this market, across different segments, as defined in the below table:

Key Report Attributes Details
Bese Year 2022
Forecast Period 2023-2035
CAGR (2026-2035)

~50%

Type of Modality

Therapeutics, Vaccines

Type of Molecule

  • Replicating RNA (repRNA)
  • Self amplifying RNA (saRNA)
  • Self activating RNA (sacRNA)
  • Self activating mRNA (samRNA)
  • Transfer RNA (tRNA)

Therapeutic Area

  • Infectious Diseases
  • Oncological Disorders
  • Pulmonary Disorders

Route of Administration

  • Intradermal
  • Intramuscular
  • Intravenous
Key Geographical Regions
  • North America
  • Europe
  • Asia-Pacific
Key Companies Profiled
  • Alphavax
  • Arcturus Therapeutics
  • Atyr Pharma
  • Gritstone Bio
  • HDT Bio
  • MiNA Therapeutics
  • VLP Therapeutics
Customization Scope 15% Free Customization Option
PowerPoint Presentation (Complimentary)

Available

Excel Data Packs (Complimentary)
  • RNA Vaccines and RNA Therapeutics Market Landscape
  • RNA Therapeutics and RNA Vaccines Technology Landscape
  • Clinical Trials Analysis
  • Patent Analysis
  • Partnerships and Collaborations
  • Funding and Investment Analysis
  • Big Pharma Initiatives
  • Market Sizing and Opportunity Analysis

The market report presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this industry, across different geographies. Amongst other elements, the market report includes:

  • A preface providing an introduction to the full report, RNA Therapeutics and RNA Vaccines Market, 2023-2035.
  • An outline of the systematic research methodology adopted to conduct the study on next generation RNA therapeutics and RNA vaccines market, providing insights on the various assumptions, methodologies, and quality control measures employed to ensure accuracy and reliability of our findings.
  • An overview of economic factors that impact the overall next generation RNA therapeutics and RNA vaccines market, including historical trends, currency fluctuation, foreign exchange impact, recession, and inflation measurement.
  • An executive summary of the insights captured during our research, offering a high-level view of the current state of the next generation RNA therapeutics and RNA vaccines market and its likely evolution in the mid-to-long term.
  • A brief introduction to the next generation RNA therapeutics and RNA vaccines, highlighting their historical background, as well as information on their types, key aspects, key challenges and the advantages of using next generation RNA modalities.
  • A detailed assessment of the market landscape of more than 100 next generation RNA therapeutics and RNA vaccines that are either approved or being evaluated in different stages of development, based on several relevant parameters, such as type of modality (therapeutics and vaccines), type of molecule (saRNA, circRNA, tRNA, sacRNA, ARC, SINEUPs, eRNA and lamRNA), type of delivery vehicle (lipid nanoparticles, viral vectors, non-lipid nanoparticles, non-viral vectors and polymers), phase of development (discovery, preclinical, phase I, phase I / II, phase II, phase II / III, phase III and emergency use approval), therapeutic area (infectious diseases, oncological disorders, genetic disorders, neurological disorders, immunological disorders and other disorders). Further, the chapter features analysis on key niche market segments (circRNA and saRNA). In addition, the chapter features analysis of various next generation RNA therapeutic and RNA vaccine developers, based on their year of establishment, company size, location of headquarters and most active players (in terms of number of therapies).
  • A detailed assessment of the market landscape of more than 35 technologies that are being developed / deployed to support the development of next generation RNA therapeutics and RNA vaccines, based on several relevant parameters, such as class of molecule (therapeutics and vaccines), type of molecule (saRNA, circRNA, tRNA, sacRNA, ARC, SINEUPs, eRNA and lamRNA), capabilities of the technology (development, delivery, research and discovery, design and manufacturing), therapeutic area (oncological disorders, infectious diseases, genetic disorders, neurological disorders, immunological disorders, cardiovascular disorders, inflammatory disorders, ophthalmic disorders, rare disorders, pulmonary disorders, unspecified and other disorders) and highest phase of development (discovery, preclinical, clinical and commercial). In addition, the chapter features analysis of various next generation RNA therapeutic and RNA vaccine technology developers, based on their year of establishment, company size, location of headquarters and operational model.
  • Elaborate profiles of drug candidates that are in advanced stages of development (Phase II, III and above). Each drug profile features details on its developer, drug overview, clinical trial information, clinical trial endpoints, clinical trial results and estimated sales.
  • An in-depth analysis of completed and ongoing clinical trials of various next generation RNA therapeutics and RNA vaccines, based on several relevant parameters, such as trial registration year, trial status, trial phase, patients enrolled, type of sponsor, therapeutic area, study design, leading organizations (in terms of number of trials), focus area and geography.
  • An in-depth analysis of patents related to next generation RNA therapeutics and RNA vaccines, filed / granted, since 2019, based on several relevant parameters, such as type of patent (granted patents, patent applications and others), patent publication year, patent jurisdiction, CPC symbols, emerging focus areas, patent age, leading industry / non-industry players (in terms of number of patents filed / granted), and patent valuation.
  • An in-depth analysis of partnerships that have been inked between various stakeholders, since 2019, based on several relevant parameters, such as the year of partnership, type of partnership, type of molecule, focus of partnership, purpose of partnership, therapeutic area and most active players (in terms of number of partnerships). It also highlights the regional distribution of partnership activity in this market. 
  • A detailed analysis of various investments made by companies engaged in this industry, since 2019, based on several relevant parameters, such as year of funding, type of funding (grants, seed, venture capital, initial public offering, secondary offerings, private equity and debt financing), type of molecule, amount invested, geography, purpose of funding, stage of development, therapeutic area, most active players (in terms of number and amount of funding instances) and leading investors (in terms of number of funding instances).
  • An in-depth analysis of the various next generation RNA therapeutics and RNA vaccines focused initiatives undertaken by big pharma players, based on several relevant parameters, such as number of initiatives, year of initiative, type of initiative, purpose of initiative, focus of initiative and location of headquarters of the big pharma players.

One of the key objectives of this market report was to estimate the current market size and the future growth potential of the next generation RNA therapeutics and RNA vaccines over the forecast period. Based on several parameters, such as region-specific adoption rates and expected prices of such modalities, we have developed informed estimates of the likely evolution of the next generation RNA vaccines and RNA therapeutics market over the forecast period 2023-2035. Our year-wise projections of the current and future opportunity have further been segmented based on relevant parameters, such as type of modality (therapeutics and vaccines), type of molecule (repRNA, saRNA, sacRNA, samRNA and tRNA), therapeutic area (infectious diseases, oncological disorders and pulmonary disorders), route of administration (intradermal, intramuscular and intravenous), key geographical regions (North America, Europe and Asia-Pacific) and leading players. In order to account for future uncertainties associated with some of the key parameters and to add robustness to our model, we have provided three market forecast scenarios, namely conservative, base, and optimistic scenarios, representing different tracks of the industry’s evolution.

All actual figures have been sourced and analyzed from publicly available information forums and secondary research. Financial figures mentioned in this report are in USD, unless otherwise specified.

Frequently Asked Questions

Question 1: What are RNA-based therapeutics?

Answer: RNA-based molecules are a class of therapeutics that utilize RNA molecules for specifically targeting genes in order to regulate their function and expression. The altered gene expression aids in the management of several disease indications by producing the desired therapeutic effect.

Question 2: What is self replicating RNA mechanism? What are self-amplifying mRNA vaccines?

Answer: The self replicating property of RNA molecules enables them to create multiple copies of themselves within the cell without using additional cellular machinery, such as proteins and DNA. The mechanism involves the use of a short RNA strand as the template guide to synthesize a complementary copy of itself, thereby generating a new RNA molecule. The two new molecules then segregate to act as the template guides for further replication.

Question 3: What are self-amplifying mRNA vaccines?

Answer: Self-amplifying mRNA vaccines utilize a strand of messenger RNA designed to self-replicate and elicit a sustained immune response when administered to the human body. Owing to the self-replicating nature, the vaccine would not require frequent administration and would lead to a higher expression of proteins even at low dose concentration.

Question 4: Are RNA-based therapies approved by the FDA?

Answer: RNA-based therapies are continuously being evaluated in clinical trials for their safety and efficacy in the treatment of a wide range of therapeutic indications. It is worth noting that the first clinical trial of an mRNA-based vaccine was conducted in 2008. However, the first mRNA vaccine received the FDA approval for the treatment of COVID in 2021.

Question 5: What RNA drugs are FDA approved?

Answer: Interestingly, close to 10 RNA therapeutics have been approved till date. Of these, the primary types of therapies include those based on antisense oligonucleotides and small interfering RNA molecules. Further, Gemcovac®, a self amplifying RNA vaccine, has been granted emergency use approval as a COVID vaccine in India.

Question 6: How big is the next generation RNA vaccines and RNA therapeutics market?

Answer: The market size for the next generation RNA therapeutics and RNA vaccines market is estimated to be USD 1.1 billion in 2035.

Question 7: What is the likely market growth rate (CAGR) for the next generation RNA vaccines and RNA therapeutics market?

Answer: The market size for next generation RNA therapeutics and RNA vaccines is projected to grow at an annualized rate (CAGR) of ~50%, during the forecast period (2026-2035).

Question 8: Who are the leading companies in the next generation RNA therapeutics and RNA vaccines market?

Answer: Some of the leading companies engaged in the next generation RNA therapeutics and RNA vaccines development (which have also been captured in this market report, arranged in alphabetical order) include Arcturus Therapeutics, Flagship Pioneering, Forge Therapeutics, Gingko Bioworks, Laronde Therapeutics, Orna Therapeutics, Recode Therapeutics, Renegade Therapeutics, Replicate Bioscience and Shape Therapeutics.

Contents

Table Of Contents

1. PREFACE
1.1. RNA Therapeutics and RNA Vaccines Market Overview
1.2. Key Market Insights
1.3. Scope of the Report
1.4. Research Methodology
1.5. Frequently Asked Questions
1.6. Chapter Outlines

2. RESEARCH METHODOLOGY
2.1. Chapter Overview
2.2. Research Assumptions
2.3. Project Methodology
2.4. Forecast Methodology
2.5. Robust Quality Control
2.6. Key Market Segmentations

2.7. Key Considerations
2.7.1. Demographics
2.7.2. Economic Factors
2.7.3. Government Regulations
2.7.4. Supply Chain
2.7.5. COVID Impact / Related Factors
2.7.6. Market Access
2.7.7. Healthcare Policies
2.7.8. Industry Consolidation

3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS
3.1. Chapter Overview
3.2. Market Dynamics
3.2.1. Time Period
3.2.1.1. Historical Trends
3.2.1.2. Current and Forecasted Estimates

3.2.2. Currency Coverage
3.2.2.1. Overview of Major Currencies Affecting the Market
3.2.2.2. Impact of Currency Fluctuations on the Industry

3.2.3. Foreign Exchange Impact
3.2.3.1. Evaluation of Foreign Exchange Rates and Their Impact on Market
3.2.3.2. Strategies for Mitigating Foreign Exchange Risk

3.2.4. Recession
3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market

3.2.5. Inflation
3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
3.2.5.2. Potential Impact of Inflation on the Market Evolution

4. EXECUTIVE SUMMARY

5. INTRODUCTION
5.1. An Overview of Next Generation RNA Therapeutics and Vaccines
5.2. Key Contributors in the Evolution of Next Generation RNA Therapeutics and Vaccines
5.3. Types of Next Generation RNA Molecules
5.4. Key Aspects of Next Generation RNA Molecules
5.5. Key Challenges Associated with Traditional RNA Modalities
5.6. Advantages of Using Next Generation RNA Modalities

6. MARKET LANDSCAPE
6.1. RNA Therapeutics and RNA Vaccines: Overall Therapies Landscape
6.1.1. Analysis by Type of Modality
6.1.2. Analysis by Type of Molecule
6.1.3. Analysis by Delivery Vehicle
6.1.4. Analysis by Phase of Development
6.1.5. Analysis by Therapeutic Area
6.1.6. Most Active Players: Analysis by Number of Therapies

6.2 RNA Therapeutics and RNA Vaccines: Clinical Stage Therapies Landscape
6.2.1. Analysis by Phase of Development
6.2.2. Analysis by Route of Administration
6.2.3. Analysis by Therapeutic Area

6.3. RNA Therapeutics and RNA Vaccines: Therapy Developers Landscape
6.3.1. Analysis by Year of Establishment
6.3.2. Analysis by Company Size
6.3.3. Analysis by Location of Headquarters

6.4. RNA Therapeutics and RNA Vaccines: Circular RNA Therapies Landscape
6.4.1. Analysis by Phase of Development
6.4.2. Analysis by Therapeutic Area
6.4.3. Most Active Players: Analysis by Number of Therapies

6.5. RNA Therapeutics and RNA Vaccines: Self-amplifying RNA Therapies Landscape
6.5.1. Analysis by Phase of Development
6.5.2. Analysis by Therapeutic Area
6.5.3. Most Active Players: Analysis by Number of Therapies

7. TECHNOLOGY LANDSCAPE
7.1. RNA Therapeutics and RNA Vaccines: Next Generation RNA Technologies Landscape
7.1.1. Analysis by Class of Molecule
7.1.2. Analysis by Type of Molecule
7.1.3. Analysis by Capabilities of the Technology
7.1.4. Analysis by Therapeutic Area
7.1.5. Analysis by Highest Phase of Development

7.2. RNA Therapeutics and RNA Vaccines: Next Generation RNA Technology / Platform Developers Landscape
7.2.1. Analysis by Year of Establishment
7.2.2. Analysis by Company Size
7.2.3. Analysis by Location of Headquarters
7.2.4. Analysis by Operational Model

8. DRUG PROFILES
8.1. Gemcovac
8.1.1. Developer Overview
8.1.2. Drug Overview
8.1.3. Clinical Trial Information
8.1.4. Clinical Trial Endpoints
8.1.5. Clinical Trial Results
8.1.6. Estimated Sales

8.2. ATYR1923
8.2.1. Developer Overview
8.2.2. Drug Overview
8.2.3. Clinical Trial Information
8.2.4. Clinical Trial Endpoints
8.2.5. Clinical Trial Results
8.2.6. Estimated Sales

8.3. ARCT-154
8.3.1. Developer Overview
8.3.2. Drug Overview
8.3.3. Clinical Trial Information
8.3.4. Clinical Trial Endpoints
8.3.5. Clinical Trial Results
8.3.6. Estimated Sales

8.4. GRT-C901
8.4.1. Developer Overview
8.4.2. Drug Overview
8.4.3. Clinical Trial Information
8.4.4. Clinical Trial Endpoints
8.4.5. Clinical Trial Results
8.4.6. Estimated Sales

8.5. VLPCOV-01
8.5.1. Developer Overview
8.5.2. Drug Overview
8.5.3. Estimated Sales

8.6. AVX901
8.6.1. Developer Overview
8.6.2. Drug Overview
8.6.3. Clinical Trial Information
8.6.4. Clinical Trial Endpoints
8.6.5. Clinical Trial Results
8.6.6. Estimated Sales

8.7. MTL-CEBPA + Sorafenib
8.7.1. Developer Overview
8.7.2. Drug Overview
8.7.3. Clinical Trial Information
8.7.4. Clinical Trial Endpoints
8.7.5. Clinical Trial Results
8.7.6. Estimated Sales

8.8. SLATE
8.8.1. Developer Overview
8.8.2. Drug Overview
8.8.3. Clinical Trial Information
8.8.4. Clinical Trial Endpoints
8.8.5. Clinical Trial Results
8.8.6. Estimated Sales

9. CLINICAL TRIAL ANALYSIS
9.1. Analysis Methodology and Key Parameters
9.2. RNA Therapeutics and RNA Vaccines: Clinical Trial Analysis
9.2.1. Analysis by Trial Registration Year
9.2.2. Analysis by Trial Status
9.2.3. Analysis by Trial Registration Year and Trial Status
9.2.4. Analysis by Trial Phase
9.2.5. Analysis by Patients Enrolled
9.2.6. Analysis by Type of Sponsor
9.2.7. Analysis by Therapeutic Area
9.2.8. Analysis by Study Design
9.2.9. Leading Organizations: Analysis by Number of Trials
9.2.10. Analysis by Focus Area
9.2.11. Analysis by Geography

10. PATENT ANALYSIS
10.1. Analysis Methodology and Key Parameters
10.2. RNA Therapeutics and RNA Vaccines: Patent Analysis
10.2.1. Analysis by Type of Patent
10.2.2. Analysis by Patent Publication Year
10.2.3. Analysis by Patent Jurisdiction
10.2.3.1. Analysis by Patent Jurisdiction: North American Scenario
10.2.3.2. Analysis by Patent Jurisdiction: European Scenario
10.2.3.3. Analysis by Patent Jurisdiction: Asia-Pacific Scenario

10.2.4. Analysis by CPC Symbols
10.2.5. World Cloud Analysis: Emerging Focus Areas
10.2.6. Analysis by Patent Age
10.2.7. Leading Industry Players: Analysis by Number of Patents
10.2.8. Leading Non-Industry Players: Analysis by Number of Patents

10.3. RNA Therapeutics and RNA Vaccines: Patent Benchmarking Analysis
10.4. RNA Therapeutics and RNA Vaccines: Patent Valuation Analysis

11. PARTNERSHIPS AND COLLABORATIONS
11.1. Partnership Models
11.2. RNA Therapeutics and RNA Vaccines: Partnerships and Collaborations
11.2.1. Analysis by Year of Partnership
11.2.2. Analysis by Type of Partnership
11.2.3. Analysis by Year and Type of Partnership
11.2.4. Analysis by Year and Type of Molecule
11.2.5. Analysis by Focus of Partnership
11.2.6. Analysis by Purpose of Partnership
11.2.7. Analysis by Therapeutic Area
11.2.8. Most Active Players: Analysis by Number of Partnerships
11.2.9. Analysis by Geography
11.2.9.1. Local and International Agreements
11.2.9.2. Intracontinental and Intercontinental Agreements

12. FUNDING AND INVESTMENT ANALYSIS
12.1. Types of Funding
12.2. RNA Therapeutics and RNA Vaccines: Funding and Investment Analysis
12.3. Analysis by Year of Funding
12.4. Analysis by Type of Funding
12.5. Analysis by Type of Molecule
12.6. Analysis of Amount Invested by Year of Funding
12.7. Analysis of Amount Invested by Type of Funding
12.8. Analysis by Geography
12.9. Analysis by Year and Type of Funding
12.10. Analysis by Purpose of Funding
12.11. Analysis by Stage of Development
12.12. Analysis by Therapeutic Area
12.13. Most Active Players: Analysis by Number of Funding Instances
12.14. Most Active Players: Analysis by Amount Invested
12.15. Leading Investors: Analysis by Number of Funding Instances

13. BIG PHARMA INITIATIVES
13.1. RNA Therapeutics and RNA Vaccines: Big Pharma Initiatives
13.1.1. Analysis by Number of Initiatives
13.1.2. Analysis by Year of Initiative
13.1.3. Analysis by Type of Initiative
13.1.3.1. Analysis by Type of Partnership
13.1.3.2. Analysis by Type of Funding

13.1.4. Analysis by Purpose of Initiative
13.1.5. Analysis by Year and Number of Initiatives
13.1.6. Analysis by Focus of Initiative
13.1.7. Analysis by Location of Headquarters of Big Pharma Players

14. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, 2023-2035
14.1. Key Assumptions and Methodology
14.2. Overall RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035)
14.2.1. Scenario Analysis

14.3. Key Market Segmentations
14.4. Dynamic Dashboard

15. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY TYPE OF MODALITY
15.1. Therapeutics: Forecasted Estimates (2023-2035)
15.2. Vaccines: Forecasted Estimates (2023-2035)
15.3. Data Triangulation and Validation

16. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY TYPE OF MOLECULE
16.1. repRNA: Forecasted Estimates (2023-2035)
16.2. saRNA: Forecasted Estimates (2023-2035)
16.3. sacRNA: Forecasted Estimates (2023-2035)
16.4. sa-mRNA: Forecasted Estimates (2023-2035)
16.5. tRNA: Forecasted Estimates (2023-2035)
16.6. Data Triangulation and Validation

17. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY THERAPEUTIC AREA
17.1. Infectious Diseases: Forecasted Estimates (2023-2035)
17.2. Oncological Disorders: Forecasted Estimates (2023-2035)
17.3. Pulmonary Disorders: Forecasted Estimates (2023-2035)
17.4. Data Triangulation and Validation
 
18. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY ROUTE OF ADMINISTRATION
18.1. Intradermal Therapeutics and Vaccines: Forecasted Estimates (2023-2035)
18.2. Intramuscular Therapeutics and Vaccines: Forecasted Estimates (2023-2035)
18.3. Intravenous Therapeutics and Vaccines: Forecasted Estimates (2023-2035)
18.4. Data Triangulation and Validation

19. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY KEY GEOGRAPHICAL REGIONS
19.1. North America: Forecasted Estimates (2023-2035)
19.1.1. US: Forecasted Estimates (2023-2035)
19.2. Europe: Forecasted Estimates (2023-2035)
19.2.1. France: Forecasted Estimates (2023-2035)
19.2.2. Italy: Forecasted Estimates (2023-2035)
19.2.3. Spain: Forecasted Estimates (2023-2035)
19.2.4. UK: Forecasted Estimates (2023-2035)
19.2.5. The Netherlands: Forecasted Estimates (2023-2035)

19.3. Asia-Pacific: Forecasted Estimates (2023-2035)
19.3.1. India: Forecasted Estimates (2023-2035)
19.3.2. Japan: Forecasted Estimates (2023-2035)
19.3.3. Singapore: Forecasted Estimates (2023-2035)

19.4. Data Triangulation and Validation

20. OVERALL RNA THERAPEUTICS AND RNA VACCINES MARKET, BY LEADING PLAYERS
20.1. Company A
20.2. Company B
20.3. Company C
20.4. Company D
20.5. Company E

21. CONCLUSION

22. APPENDIX 1: TABULATED DATA

23. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List Of Figures

Figure 4.1 Executive Summary: Overall Market Landscape
Figure 4.2 Executive Summary: Overall Technology Landscape
Figure 4.3 Executive Summary: Clinical Trial Analysis
Figure 4.4 Executive Summary: Patent Analysis
Figure 4.5 Executive Summary: Partnerships and Collaborations
Figure 4.6 Executive Summary: Funding and Investment Analysis
Figure 4.7 Executive Summary: Big Pharma Initiatives
Figure 4.8 Executive Summary: Market Forecast and Opportunity Analysis
Figure 5.1 Key Contributors in the Evolution of Next Generation RNA Therapeutics and Vaccines
Figure 5.2 Key Aspects of Next Generation RNA Molecules
Figure 5.3 Key Challenges Associated with Traditional RNA Modalities
Figure 5.4 Advantages of Using Next Generation RNA Modalities
Figure 6.1 Next Generation RNA Therapies: Distribution by Type of Modality
Figure 6.2 Next Generation RNA Therapies: Distribution by Type of Molecule
Figure 6.3 Next Generation RNA Therapies: Distribution by Delivery Vehicle
Figure 6.4 Next Generation RNA Therapies: Distribution by Phase of Development
Figure 6.5 Next Generation RNA Therapies: Distribution by Therapeutic Area
Figure 6.6 Most Active Players: Distribution by Number of Therapies
Figure 6.7 Clinical Stage Therapies: Distribution by Phase of Development
Figure 6.8 Clinical Stage Therapies: Distribution by Route of Administration
Figure 6.9 Clinical Stage Therapies: Distribution by Therapeutic Area
Figure 6.10 Therapy Developer Landscape: Distribution by Year of Establishment
Figure 6.11 Therapy Developer Landscape: Distribution by Company Size
Figure 6.12 Therapy Developer Landscape: Distribution by Location of Headquarters
Figure 6.13 circRNA Therapies: Distribution by Phase of Development
Figure 6.14 circRNA Therapies: Distribution by Therapeutic Area
Figure 6.15 Most Active Players: Distribution by Number of circRNA Therapies
Figure 6.16 saRNA Therapies: Distribution by Phase of Development
Figure 6.17 saRNA Therapies: Distribution by Therapeutic Area
Figure 6.18 Most Active Players: Distribution by Number of saRNA Therapies
Figure 7.1 Next Generation RNA Technologies: Distribution by Class of Molecule
Figure 7.2 Next Generation RNA Technologies: Distribution by Type of Molecule
Figure 7.3 Next Generation RNA Technologies: Distribution by Capabilities of the Technology
Figure 7.4 Next Generation RNA Technologies: Distribution by Therapeutic Area
Figure 7.5 Next Generation RNA Technologies: Distribution by Highest Phase of Development
Figure 7.6 Technology Developer Landscape: Distribution by Year of Establishment
Figure 7.7 Technology Developer Landscape: Distribution by Company Size
Figure 7.8 Technology Developer Landscape: Distribution by Location of Headquarters
Figure 7.9 Technology Developer Landscape: Distribution by Operational Model
Figure 8.1 Gemcovac®: Estimated Sales
Figure 8.2 ATYR1923: Estimated Sales
Figure 8.3 ARCT-154: Estimated Sales
Figure 8.4 GRT-C901: Estimated Sales
Figure 8.5 VLPCOV-01: Estimated Sales
Figure 8.6 AVX901: Estimated Sales
Figure 8.7 MTL-CEBPA + Sorafenib: Estimated Sales
Figure 8.8 SLATE: Estimated Sales
Figure 9.1 Clinical Trial Analysis: Cumulative Year-wise Trend, Pre-2019-2023
Figure 9.2 Clinical Trial Analysis: Distribution by Trial Status
Figure 9.3 Clinical Trial Analysis: Distribution by Trial Registration Year and Trial Status, Pre-2019-2022
Figure 9.4 Clinical Trial Analysis: Distribution by Trial Phase
Figure 9.5 Clinical Trial Analysis: Distribution by Patients Enrolled
Figure 9.6 Clinical Trial Analysis: Distribution by Type of Sponsor
Figure 9.7 Clinical Trial Analysis: Distribution by Therapeutic Area
Figure 9.8 Clinical Trial Analysis: Distribution by Study Design
Figure 9.9 Leading Organizations: Distribution by Number of Trials
Figure 9.10 Clinical Trial Analysis: Distribution by Focus Area
Figure 9.11 Clinical Trial Analysis: Distribution by Geography
Figure 10.1 Patent Analysis: Distribution by Type of Patent
Figure 10.2 Patent Analysis: Cumulative Year-wise Trend, 2019-2023
Figure 10.3 Patent Analysis: Distribution by Patent Jurisdiction
Figure 10.4 Patent Jurisdiction: North American Scenario
Figure 10.5 Patent Jurisdiction: European Scenario
Figure 10.6 Patent Jurisdiction: Aisa-Pacific Scenario
Figure 10.7 Patent Analysis: Distribution by Patent Age
Figure 10.8 Patent Analysis: Distribution by CPC Symbols
Figure 10.9 Word Cloud Analysis: Emerging Focus Areas
Figure 10.10 Leading Industry Players: Distribution by Number of Patents
Figure 10.11 Leading Non-Industry Players: Distribution by Number of Patents
Figure 10.12 Patent Analysis: Distribution by Patent Characteristics
Figure 10.13 RNA Therapeutics and RNA Vaccines: Patent Valuation Analysis
Figure 11.1 Partnerships and Collaborations: Cumulative Year-wise Trend, 2019-2023
Figure 11.2 Partnerships and Collaborations: Distribution by Type of Partnership
Figure 11.3 Partnerships and Collaborations: Distribution by Year and Type of Partnership, 2019-2023
Figure 11.4 Partnerships and Collaborations: Distribution by Year and Type of Molecule, 2019-2023
Figure 11.5 Partnerships and Collaborations: Distribution by Focus of Partnership
Figure 11.6 Partnerships and Collaborations: Distribution by Purpose of Partnership
Figure 11.7 Partnerships and Collaborations: Distribution by Therapeutic Area
Figure 11.8 Most Active Players: Distribution by Number of Partnerships
Figure 11.9 Partnerships and Collaborations: Local and International Deals
Figure 11.10 Partnerships andCollaborations: Intercontinental and Intracontinental Deals
Figure 12.1 Funding and Investment Analysis: Cumulative Year-wise Trend, 2019-2023
Figure 12.2 Funding and Investment Analysis: Distribution by Type of Funding
Figure 12.3 Funding and Investment Analysis: Distribution by Type of Molecule
Figure 12.4 Funding and Investment Analysis: Cumulative Amount Invested by Year, 2019-2023 (USD Million)
Figure 12.5 Funding and Investment Analysis: Distribution of Amount Invested by Type of Funding (USD Million)
Figure 12.6 Funding and Investment Analysis: Distribution of Amount Invested by Geography (USD Million)
Figure 12.7 Funding and Investment Analysis: Distribution by Year and Type of Funding, 2019-2023
Figure 12.8 Funding and Investment Analysis: Distribution by Purpose of Funding
Figure 12.9 Funding and Investment Analysis: Distribution by Stage of Development
Figure 12.10 Funding and Investment Analysis: Distribution by Therapeutic Area
Figure 12.11 Most Active Players: Distribution by Number of Funding Instances
Figure 12.12 Most Active Players: Distribution by Amount Invested (USD Million)
Figure 12.13 Leading Investors: Distribution by Number of Funding Instances
Figure 13.1 Big Pharma Initiatives: Distribution by Number of Initiatives
Figure 13.2 Big Pharma Initiatives: Cumulative Distribution by Year of Initiative
Figure 13.3 Big Pharma Initiatives: Distribution by Type of Initiative
Figure 13.4 Big Pharma Initiatives: Cumulative Distribution by Purpose of Initiative
Figure 13.5 Big Pharma Initiatives: Cumulative Year-wise Trend, 2019-2023
Figure 13.6 Big Pharma Initiatives: Distribution by Focus of Initiative
Figure 13.7 Big Pharma Initiatives: Distribution by Location of Headquarters of Big Pharma Players
Figure 14.1 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), BaseScenario (USD Million)
Figure 14.2 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), Conservative Scenario (USD Million)
Figure 14.3 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), Optimistic Scenario (USD Million)
Figure 15.1 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Type of Modality, 2023, 2028 and 2035 (USD Million)
Figure 15.2 Global RNA Therapeutics Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 15.3 Global RNA Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 16.1 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Type of Molecule, 2023, 2028 and 2035 (USD Million)
Figure 16.2 Global repRNA Therapeutics Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 16.3 Global saRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 16.4 Global sacRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 16.5 Global sa-mRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 16.6 Global tRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Figure 17.1 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Therapeutic Area, 2023, 2028 and 2035 (USD Million)
Figure 17.2 Global RNA Therapeutics and RNA Vaccines Market for Infectious Diseases, Forecasted Estimates (2023-2035) (USD Million)
Figure 17.3 Global RNA Therapeutics and RNA Vaccines Market for Oncological Disorders, Forecasted Estimates (2023-2035) (USD Million)
Figure 17.4 Global RNA Therapeutics and RNA Vaccines Market for Pulmonary Disorders, Forecasted Estimates (2023-2035) (USD Million)
Figure 18.1 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Route of Administration, 2023, 2028 and 2035 (USD Million)
Figure 18.2 Global RNA Therapeutics and RNA Vaccines Market for Intradermal Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Figure 18.3 Global RNA Therapeutics and RNA Vaccines Market for Intramuscular Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Figure 18.4 Global RNA Therapeutics and RNA Vaccines Market for Intravenous Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.1 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Key Geographical Regions, 2023, 2028 and 2035 (USD Million)
Figure 19.2 RNA Therapeutics and RNA Vaccines Market in North America, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.3 RNA Therapeutics and RNA Vaccines Market in the US, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.4 RNA Therapeutics and RNA Vaccines Market in Europe, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.5 RNA Therapeutics and RNA Vaccines Market in France, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.6 RNA Therapeutics and RNA Vaccines Market in Italy, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.7 RNA Therapeutics and RNA Vaccines Market in Spain, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.8 RNA Therapeutics and RNA Vaccines Market in the UK, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.9 RNA Therapeutics and RNA Vaccines Market in the Netherlands, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.10 RNA Therapeutics and RNA Vaccines Market in Asia-Pacific, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.11 RNA Therapeutics and RNA Vaccines Market in India, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.12 RNA Therapeutics and RNA Vaccines Market in Japan, Forecasted Estimates (2023-2035) (USD Million)
Figure 19.13 RNA Therapeutics and RNA Vaccines Market in Singapore, Forecasted Estimates (2023-2035) (USD Million)
Figure 20.1 RNA Therapeutics and RNA Vaccines Market: Distribution by Leading Players, 2023, 2028 and 2035 (USD Million)

List Of Tables

Table 6.1 List of Next Generation RNA Therapeutics and RNA Vaccines
Table 6.2 List of Clinical Stage Next Generation RNA Therapeutics and RNA Vaccines
Table 6.3 List of Next Generation RNA Therapeutic and RNA Vaccine Developers
Table 7.1 List of Next Generation RNA Technologies
Table 7.2 List of Next Generation RNA Technology / Platform Developers
Table 8.1 Gemcovac®: Developer Overview
Table 8.2 Gemcovac®: Drug Overview
Table 8.3 Gemcovac®: Clinical Trial Information
Table 8.4 Gemcovac®: Clinical Trial Endpoints
Table 8.5 Gemcovac®: Clinical Trial Results
Table 8.6 ATYR1923: Developer Overview
Table 8.7 ATYR1923: Drug Overview
Table 8.8 ATYR1923: Clinical Trial Information
Table 8.9 ATYR1923: Clinical Trial Endpoints
Table 8.10 ATYR1923: Clinical Trial Results
Table 8.11 ARCT-154: Developer Overview
Table 8.12 ARCT-154: Drug Overview
Table 8.13 ARCT-154: Clinical Trial Information
Table 8.14 ARCT-154: Clinical Trial Endpoints
Table 8.15 ARCT-154: Clinical Trial Results
Table 8.16 GRT-C901: Developer Overview
Table 8.17 GRT-C901: Drug Overview
Table 8.18 GRT-C901: Clinical Trial Information
Table 8.19 GRT-C901: Clinical Trial Endpoints
Table 8.20 GRT-C901: Clinical Trial Results
Table 8.21 VLPCOV-01: Developer Overview
Table 8.22 VLPCOV-01: Drug Overview
Table 8.23 AVX-901: Developer Overview
Table 8.24 AVX-901: Drug Overview
Table 8.25 AVX-901: Clinical Trial Information
Table 8.26 AVX-901: Clinical Trial Endpoints
Table 8.27 AVX-901: Clinical Trial Results
Table 8.28 MTL-CEBPA + Sorafenib: Developer Overview
Table 8.29 MTL-CEBPA + Sorafenib: Drug Overview
Table 8.30 MTL-CEBPA + Sorafenib: Clinical Trial Information
Table 8.31 MTL-CEBPA + Sorafenib: Clinical Trial Endpoints
Table 8.32 MTL-CEBPA + Sorafenib: Clinical Trial Results
Table 8.33 SLATE: Developer Overview
Table 8.34 SLATE: Drug Overview
Table 8.35 SLATE: Clinical Trial Information
Table 8.36 SLATE: Clinical Trial Endpoints
Table 8.37 SLATE: Clinical Trial Results
Table 9.1 RNA Therapeutics and RNA Vaccines: List of Clinical Trials, Pre-2019-2023
Table 10.1 RNA Therapeutics and RNA Vaccines: List of Filed / Granted Patents, 2019-2023
Table 11.1 RNA Therapeutics and RNA Vaccines: List of Partnerships and Collaborations, 2019-2023
Table 12.1 RNA Therapeutics and RNA Vaccines: List of Funding and Investments, 2019-2023
Table 13.1 RNA Therapeutics and RNA Vaccines: List of Big Pharma Initiatives, 2019-2023
Table 14.1 RNA Therapeutics and RNA Vaccines Market: Expected Launch Year of Forecasted Drug Candidates
Table 22.1 Next Generation RNA Therapies: Distribution by Type of Modality
Table 22.2 Next Generation RNA Therapies: Distribution by Type of Molecule
Table 22.3 Next Generation RNA Therapies: Distribution by Delivery Vehicle
Table 22.4 Next Generation RNA Therapies: Distribution by Phase of Development
Table 22.5 Next Generation RNA Therapies: Distribution by Therapeutic Area
Table 22.6 Most Active Players: Distribution by Number of Therapies
Table 22.7 Clinical Stage Therapies: Distribution by Phase of Development
Table 22.8 Clinical Stage Therapies: Distribution by Route of Administration
Table 22.9 Clinical Stage Therapies: Distribution by Therapeutic Area
Table 22.10 Therapy Developer Landscape: Distribution by Year of Establishment
Table 22.11 Therapy Developer Landscape: Distribution by Company Size
Table 22.12 Therapy Developer Landscape: Distribution by Location of Headquarters
Table 22.13 circRNA Therapies: Distribution by Phase of Development
Table 22.14 circRNA Therapies: Distribution by Therapeutic Area
Table 22.15 Most Active Players: Distribution by Number of circRNA Therapies
Table 22.16 saRNA Therapies: Distribution by Phase of Development
Table 22.17 saRNA Therapies: Distribution by Therapeutic Area
Table 22.18 Most Active Players: Distribution by Number of saRNA Therapies
Table 22.19 Next Generation RNA Technologies: Distribution by Class of Molecule
Table 22.20 Next Generation RNA Technologies: Distribution by Type of Molecule
Table 22.21 Next Generation RNA Technologies: Distribution by Capabilities of the Technology
Table 22.22 Next Generation RNA Technologies: Distribution by Therapeutic Area
Table 22.23 Next Generation RNA Technologies: Distribution by Highest Phase of Development
Table 22.24 Technology Developer Landscape: Distribution by Year of Establishment
Table 22.25 Technology Developer Landscape: Distribution by Company Size
Table 22.26 Technology Developer Landscape: Distribution by Location of Headquarters
Table 22.27 Technology Developer Landscape: Distribution by Operational Model
Table 22.28 Gemcovac®: Estimated Sales
Table 22.29 ATYR1923: Estimated Sales
Table 22.30 ARCT-154: Estimated Sales
Table 22.31 GRT-C901: Estimated Sales
Table 22.32 VLPCOV-01: Estimated Sales
Table 22.33 AVX901: Estimated Sales
Table 22.34 MTL-CEBPA + Sorafenib: Estimated Sales
Table 22.35 SLATE: Estimated Sales
Table 22.36 Clinical Trial Analysis: Cumulative Year-wise Trend, Pre-2019-2023
Table 22.37 Clinical Trial Analysis: Distribution by Trial Status
Table 22.38 Clinical Trial Analysis: Distribution by Trial Registration Year and Trial Status, Pre-2019-2022
Table 22.39 Clinical Trial Analysis: Distribution by Trial Phase
Table 22.40 Clinical Trial Analysis: Distribution by Patients Enrolled
Table 22.41 Clinical Trial Analysis: Distribution by Type of Sponsor
Table 22.42 Clinical Trial Analysis: Distribution by Therapeutic Area
Table 22.43 Clinical Trial Analysis: Distribution by Study Design
Table 22.44 Leading Organizations: Distribution by Number of Trials
Table 22.45 Clinical Trial Analysis: Distribution by Focus Area
Table 22.46 Clinical Trial Analysis: Distribution by Geography
Table 22.47 Patent Analysis: Distribution by Type of Patent
Table 22.48 Patent Analysis: Cumulative Year-wise Trend, 2019-2023
Table 22.49 Patent Analysis: Distribution by Patent Jurisdiction
Table 22.50 Patent Jurisdiction: North American Scenario
Table 22.51 Patent Jurisdiction: European Scenario
Table 22.52 Patent Jurisdiction: Aisa-Pacific Scenario
Table 22.53 Patent Analysis: Distribution by Patent Age
Table 22.54 Patent Analysis: Distribution by CPC Symbols
Table 22.55 Leading Industry Players: Distribution by Number of Patents
Table 22.56 Leading Non-Industry Players: Distribution by Number of Patents
Table 22.57 Patent Analysis: Distribution by Patent Characteristics
Table 22.58 RNA Therapeutics and RNA Vaccines: Patent Valuation Analysis
Table 22.59 Partnerships and Collaborations: Cumulative Year-wise Trend, 2019-2023
Table 22.60 Partnerships and Collaborations: Distribution by Type of Partnership
Table 22.61 Partnerships and Collaborations: Distribution by Year and Type of Partnership, 2019-2023
Table 22.62 Partnerships and Collaborations: Distribution by Year and Type of Molecule, 2019-2023
Table 22.63 Partnerships and Collaborations: Distribution by Focus of Partnership
Table 22.64 Partnerships and Collaborations: Distribution by Purpose of Partnership
Table 22.65 Partnerships and Collaborations: Distribution by Therapeutic Area
Table 22.66 Most Active Players: Distribution by Number of Partnerships
Table 22.67 Partnerships and Collaborations: Local and International Deals
Table 22.68 Partnerships and Collaborations: Intercontinental and Intracontinental Deals
Table 22.69 Funding and Investment Analysis: Cumulative Year-wise Trend, 2019-2023
Table 22.70 Funding and Investment Analysis: Distribution by Type of Funding
Table 22.71 Funding and Investment Analysis: Distribution by Type of Molecule
Table 22.72 Funding and Investment Analysis: Cumulative Amount Invested by Year, 2019-2023 (USD Million)
Table 22.73 Funding and Investment Analysis: Distribution of Amount Invested by Type of Funding (USD Million)
Table 22.74 Funding and Investment Analysis: Distribution of Amount Invested by Geography (USD Million)
Table 22.75 Funding and Investment Analysis: Distribution by Year and Type of Funding, 2019-2023
Table 22.76 Funding and Investment Analysis: Distribution by Purpose of Funding
Table 22.77 Funding and Investment Analysis: Distribution by Stage of Development
Table 22.78 Funding and Investment Analysis: Distribution by Therapeutic Area
Table 22.79 Most Active Players: Distribution by Number of Funding Instances
Table 22.80 Most Active Players: Distribution by Amount Invested (USD Million)
Table 22.81 Leading Investors: Distribution by Number of Funding Instances
Table 22.82 Big Pharma Initiatives: Distribution by Number of Initiatives
Table 22.83 Big Pharma Initiatives: Cumulative Distribution by Year of Initiative, 2019-2023
Table 22.84 Big Pharma Initiatives: Distribution by Type of Initiative
Table 22.85 Big Pharma Initiatives: Cumulative Distribution by Purpose of Initiative
Table 22.86 Big Pharma Initiatives: Cumulative Year-wise Trend, 2019-2023
Table 22.87 Big Pharma Initiatives: Distribution by Focus of Initiative
Table 22.88 Big Pharma Initiatives: Distribution by Location of Headquarters of Big Pharma Players
Table 22.89 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), Base Scenario (USD Million)
Table 22.90 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), Conservative Scenario (USD Million)
Table 22.91 Global RNA Therapeutics and RNA Vaccines Market, Forecasted Estimates (2023-2035), Optimistic Scenario (USD Million)
Table 22.92 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Type of Modality, 2023, 2028 and 2035 (USD Million)
Table 22.93 Global RNA Therapeutics Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.94 Global RNA Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.95 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Type of Molecule, 2023, 2028 and 2035 (USD Million)
Table 22.96 Global repRNA Therapeutics Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.97 Global saRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.98 Global sacRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.99 Global sa-mRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.100 Global tRNA Therapeutics and Vaccines Market, Forecasted Estimates (2023-2035) (USD Million)
Table 22.101 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Therapeutic Area, 2023, 2028 and 2035 (USD Million)
Table 22.102 Global RNA Therapeutics and RNA Vaccines Market for Infectious Diseases, Forecasted Estimates (2023-2035) (USD Million)
Table 22.103 Global RNA Therapeutics and RNA Vaccines Market for Oncological Disorders, Forecasted Estimates (2023-2035) (USD Million)
Table 22.104 Global RNA Therapeutics and RNA Vaccines Market for Pulmonary Disorders, Forecasted Estimates (2023-2035) (USD Million)
Table 22.105 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Route of Administration, 2023, 2028 and 2035 (USD Million)
Table 22.106 Global RNA Therapeutics and RNA Vaccines Market for Intradermal Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Table 22.107 Global RNA Therapeutics and RNA Vaccines Market for Intramuscular Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Table 22.108 Global RNA Therapeutics and RNA Vaccines Market for Intravenous Therapeutics / Vaccines, Forecasted Estimates (2023-2035) (USD Million)
Table 22.109 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Key Geographical Regions, 2023, 2028 and 2035 (USD Million)
Table 22.110 RNA Therapeutics and RNA Vaccines Market in North America, Forecasted Estimates (2023-2035) (USD Million)
Table 22.111 RNA Therapeutics and RNA Vaccines Market in the US, Forecasted Estimates (2023-2035) (USD Million)
Table 22.112 RNA Therapeutics and RNA Vaccines Market in Europe, Forecasted Estimates (2023-2035) (USD Million)
Table 22.113 RNA Therapeutics and RNA Vaccines Market in France, Forecasted Estimates (2023-2035) (USD Million)
Table 22.114 RNA Therapeutics and RNA Vaccines Market in Italy, Forecasted Estimates (2023-2035) (USD Million)
Table 22.115 RNA Therapeutics and RNA Vaccines Market in Spain, Forecasted Estimates (2023-2035) (USD Million)
Table 22.116 RNA Therapeutics and RNA Vaccines Market in the UK, Forecasted Estimates (2023-2035) (USD Million)
Table 22.117 RNA Therapeutics and RNA Vaccines Market in the Netherlands, Forecasted Estimates (2023-2035) (USD Million)
Table 22.118 RNA Therapeutics and RNA Vaccines Market in Asia-Pacific, Forecasted Estimates (2023-2035) (USD Million)
Table 22.119 RNA Therapeutics and RNA Vaccines Market in India, Forecasted Estimates (2023-2035) (USD Million)
Table 22.120 RNA Therapeutics and RNA Vaccines Market in Japan, Forecasted Estimates (2023-2035) (USD Million)
Table 22.121 RNA Therapeutics and RNA Vaccines Market in Singapore, Forecasted Estimates (2023-2035) (USD Million)
Table 22.122 Global RNA Therapeutics and RNA Vaccines Market: Distribution by Leading Players, 2023, 2028 and 2035 (USD Million)

List Of Companies

The following companies / institutes / government bodies and organizations have been mentioned in this report:

  1. 4SR Biosciences
  2. 8VC
  3. Alexandria Real Estate Equities
  4. Alltrna
  5. AlphaVax
  6. aMoon
  7. Apple Tree Partners
  8. Arcturus Therapeutics
  9. Aspire Capital
  10. AstraZeneca
  11. Atlas Special Opportunities
  12. aTyr Pharma
  13. Aurora Vaccines
  14. Avidity Partners
  15. AyurMaya Capital Management Fund
  16. BeiGene
  17. MPM BioImpact
  18. BioNTech
  19. Camford Capital
  20. Catalent
  21. Charles River
  22. Chimerna Therapeutics
  23. Chimeron Bio
  24. Circio
  25. Circularis
  26. Coalition for Epidemic Preparedness Innovations (CEPI)
  27. Colt Ventures
  28. Cowen Healthcare Investments
  29. Creative Biolabs
  30. CSL Behring
  31. CSL Seqirus
  32. CureVac
  33. Curia
  34. Dualsystems Biotech
  35. Duke-NUS Medical School
  36. EcoR1 Capital
  37. Eli Lilly
  38. Elixirgen Therapeutics
  39. Epidarex
  40. Esperovax
  41. F2 Ventures
  42. Flagship Pioneering
  43. FPV Ventures
  44. Frazier Life Sciences
  45. Friends of FSH Research
  46. FUJIFILM
  47. FUJIFILM Diosynth Biotechnologies
  48. Genevant Sciences
  49. George Mason University
  50. Gilead Sciences
  51. Ginkgo Bioworks
  52. GlaxoSmithKline
  53. Gritstone bio
  54. hC Bioscience
  55. HDT Bio
  56. Hercules Capital
  57. ImmunityBio
  58. Imperial College London
  59. Israeli Ministry of Health
  60. Japanese Ministry of Economy, Trade and Industry (METI)
  61. K2 HealthVentures
  62. Konishiyasu
  63. KYORIN Pharmaceutical
  64. Laronde
  65. Leaps by Bayer
  66. Levatio Therapeutics
  67. Maryland Industrial Partnerships
  68. thisMerck
  69. Michigan Rise
  70. MiNA Therapeutics
  71. miRecule
  72. Miyako Capital
  73. MPM Capital
  74. MSA Capital
  75. MUFG Bank
  76. National Cancer Institute (NCI)
  77. National Institutes of Health
  78. Nobelpharma
  79. Oncorus
  80. OrbiMed
  81. Orbital Therapeutics
  82. Orna Therapeutics
  83. Pan African Cancer Research Institute (PACRI)
  84. Panacea Venture
  85. Perceptive Advisors
  86. Pfizer
  87. Playground Global
  88. Precision NanoSystems
  89. Quanchuang Capital
  90. Recipharm
  91. ReCode Therapeutics
  92. Redmile Group
  93. Replicate Bioscience
  94. Ring Code Biotech
  95. Sanofi
  96. Servier
  97. ShapeTX
  98. Silicon Valley Bank
  99. Simnova
  100. SK Impact Fund
  101. Sojitz
  102. Solve FSHD
  103. Strand Therapeutics
  104. SYTE.bio
  105. Taiho Ventures
  106. Takeda Ventures
  107. Tevard Biosciences
  108. Biomedical Advanced Research and Development Authority (BARDA)
  109. Coalition for Epidemic Preparedness Innovations (CEPI)
  110. National Institute of Allergy and Infectious Diseases
  111. The National University Cancer Institute, Singapore (NCIS)
  112. University of Nebraska Medical Center
  113. The University of Texas Medical Branch (UTMB)
  114. Therorna
  115. Transine Therapeutics
  116. TriLink BioTechnologies
  117. University of Antwerp
  118. UZ Gent
  119. VaxEquity
  120. Vertex Pharmaceuticals
  121. Vida Ventures
  122. Vingroup
  123. VLP Therapeutics
  124. Ziphius Vaccines
  125. Zogenix (Acquired by UCB)
  126. Zoic Capital

Source 1: https://www.biospace.com/article/releases/esperovax-and-ginkgo-bioworks-announce-partnership-to-develop-circular-rna-based-therapeutics/
Source 2: https://www.hdt.bio/news-blog/hdt-bio-to-develop-rna-cancer-vaccines-and-treatments-with-south-africas-pan-african-cancer-research-institute-pacri

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