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Pharmaceutical Spray Drying Market (2nd Edition), 2018-2028

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    April 2018

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Example Insights

  1. Over 50 companies are offering spray drying services for pharmaceutical products. At present, the market is highly fragmented and features a mix of established companies (>500 employees, 48%), mid-sized companies (51-500 employees, 27%) and small-sized companies (<50 employees, 25%). Of the total number of service providers, 26 companies offer spray drying services at all three (laboratory, clinical and industrial) scales of operation. Examples of these companies include (in alphabetical order, no selection criteria) Catalent Pharma Solutions, Evotec, Patheon, Pulse Combustion Systems and Siegfried.
  2. The market is also characterized by presence of over 20 manufacturers that have, so far, developed 86 spray dryers for use in the pharmaceutical industry. Of these, 35% of companies are established players, 30% are mid-sized companies and 35% are small-sized companies. Majority of the spray dryers being developed by these manufacturers (38%) use a fluid nozzle (particularly 2-fluid nozzles), while others use rotary disc atomizers (8%), and centrifugal (7%) and pressure nozzles (7%). Interestingly, the rest of the spray dryers are compatible with multiple nozzle types.
  3. With respect to maximum inlet temperature, most of the spray dryers (48%) can operate at temperatures ranging from 151◦C to 250◦C. Around 11% of the dryers have maximum inlet temperatures of more than 350◦C. Of all the systems that we identified, 70% use air as the atomizing gas. However, in the rest (30%) of the spray dryers, the mode of operation is aseptic and is carried out in a closed loop configuration, using nitrogen or other inert gases.
  4. A significant number of companies (close to 70% of the facilities captured in our database) offering pharmaceutical spray drying services are based in North America and Europe. Notable examples of mid-sized and small-sized players based in North America and the US include (in alphabetical order) Coriolis Pharma, Formurex, Leukocare, North Star Processing, Norwich Pharmaceuticals, Nova Laboratories, PacMoore, Richman Chemical, Spray-Tek, Summit Custom Spray Drying, Ufag Laboratorien, Upperton and Vectura. Within Europe, majority of the contract service providers are located in Italy, Germany, France, Spain and the UK. Examples of established players that have business operations in these geographies include (in alphabetical order) AMRI Global, Capsugel (now a part of Lonza), Catalent Pharma Solutions, Juniper Pharma Services and Siegfried. Asia Pacific has 25% of the players offering spray drying services for pharmaceuticals, while 6% of service providers are based in Africa, Latin America, South America and rest of the world.
  5. Several CMOs (close to 30) have installed spray dryers developed by GEA Niro in their facilities. Amongst the 15 types of spray dryers offered by GEA Niro, its PSD and GEA Niro Mobile Minor™ models are most commonly used. In addition, spray dryers developed by Buchi (B-290 and B-90 models) are being used by a number of service providers. Spray dryers offered by SPX and ProCepT are also gaining popularity amongst the service providers.
  6. We expect the pharmaceutical spray drying services market to grow at an annualized rate of ~20% between 2018 and 2028. North America (primarily US) and Europe currently capture the largest market share (close to 70%) in the spray drying contract services market. This is followed by Asia Pacific and rest of the world. Markets in Asia-Pacific are expected to grow at a relatively higher CAGR owing to inherent advantages such as relatively low labor costs and less stringent regulatory constraints.
  7. The current market is driven, to a large extent (over 80%), by pharmaceutical products (such as APIs and intermediate products). The future advances will be jointly led by the steady rise of the biopharmaceuticals’ market; emergence of new technologies / applications is likely to provide the necessary impetus to fuel this growth.

Overview

From my point of view, the prospects of spray drying for pharmaceutical products are promising. I believe that this technology may turn out to be a well-suited option for value added generics (or super generics); further, depending on the evolution of the aforementioned products, the growth may be impacted

-Director, Business Development, Spain based small-sized CMO

The origins of spray drying can be traced back to 1872, when the first patent related to the technique was registered in the US. The first commercial use of this form of drying was reported in the 1920s when powdered milk was introduced into the market. Spray drying, which is already established in the food and chemical sector, is also considered to be a rapid, cost-effective, and scalable process for the production of dry powder formulations of pharmacological material. Owing to characteristics, such as reproducibility and its continuous mode of operation, the technique has become very popular in the pharmaceutical and biotechnology industry. It offers several advantages over alternate drying technologies, such as lyophilization (characterized by high dependence on cold chain for storage and logistics, which is prone to failure due to human error) and vacuum foam drying (characterized by volumetric restrictions due to the properties of foam, which limits the quantity of sample that can be dried in a single run) that are currently deployed in the pharmaceutical industry.

Amongst other merits, spray drying is known to be suitable for drying heat-sensitive products such as biologics. Moreover, this method imparts improved properties to the formulations that can be administered through more efficient and less invasive modes of delivery, such as oral, and inhalation routes. The technology also aids in improving the compression properties of drugs, allowing developers to design concentrated dose variants of medications and reduce tablet size. Such alterations have the potential to improve patient compliance. Given the flexibility offered in terms of drug development and formulation, the economics of the technique, the introduction of aseptic methods, and the recent approval of the first spray dried biologic, Raplixa ®, the adoption of spray drying is anticipated to increase steadily in the pharmaceutical industry.

 

Scope of the Report

The ‘Pharmaceutical Spray Drying Market (2nd Edition), 2018-2028’ report provides an extensive study on the use of spray drying in the pharmaceutical sector. The key focus of the report is primarily to estimate the future potential of spray drying in the manufacturing of APIs, inhalables, injectables, biologics and other pharmaceutical products. The study presents an in-depth analysis of a diverse set of companies that provide spray drying equipment and services across different regions of the globe.Amongst other elements, the report includes:

  • A detailed discussion the applications of spray drying in the pharmaceutical industry; these include enhancement of solubility and bioavailability, formulation of inhalables, taste masking, development of controlled release formulations, and aseptic production of biopharmaceuticals.
  • An assessment of the various players that are engaged in the manufacturing of spray dryers used in the pharmaceutical industry, including a detailed analysis of their products based on inlet temperature, type of nozzle (fluid, pressure, rotary disc, centrifugal and others), size of the dryer (lab, clinical and commercial) and atomizing gas (air, nitrogen and inert gases).
  • An overview of the current market landscape of spray drying service providers, featuring an analysis based on the location of their operating facilities, type of spray dryers used, scale of operation (lab, clinical and commercial), information on cGMP status of their facilitiesand availability of fill / finish services.
  • An insightful 2X2 analysis of different spray drying service providers. This analysis is based on the spray drying capabilities (represented in terms of number of manufacturing sites, scale of operation and the types of spray dryers used) and the company size. In addition, similar analysis has been done to compare the spray dryer manufacturers. This assessment is based on the company’s spray drying portfolio (number of spray dryers offered and availability of spray drying services), company’s year of establishment and the geographical coverage of its client base.
  • Tabulated profiles of the players offering spray drying services, featuring company overview, service portfolio, spray dryers used, and key developments related to its spray drying capabilities.
  • Detailed profiles of spray dryer manufacturers, featuring an overview of the company, its financial information (if available), types of spray dryers in their respective product portfolios, recent developments and a comprehensive future outlook.
  • A case study on the lyophilization of biologics, highlighting the underlying process, its applications, and merits and demerits. It features a detailed list of companies offering lyophilization services with information on location of facilities, types of drug candidates lyophilized, scale of operation and the containment systems utilized for such operations.
  • A detailed analysis of the mergers and acquisitions that have taken place in this space, highlighting the trend in the number of companies acquired in the last few years, along with the geographical distribution of this activity. The analysis highlights the ownership change matrix and presents financial evaluation of these deals (revenues and respective deal multiples).
  • A detailed discussion on affiliated trends, key drivers and challenges, under a SWOT framework.

One of the key objectives of the report was to understand the primary growth drivers and estimate the future size of the market. Based on parameters, such as trends in the pharmaceutical contract manufacturing industry, operation costs associated with spray drying and the challenges and opportunities presented by this technique, we have provided an informed estimate of the likely evolution of the market in the long term, for the period 2018-2028. In addition, we have provided insights on the likely regional evolution of the market in North America, Europe, Asia Pacific and the rest of the world. It also includes estimates regarding the likely distribution of the market based on type of industry (pharmaceuticals and biologics) and type of nozzles used in spray dryers (fluid nozzle, pressure nozzle, rotary disc atomizer, centrifugal nozzle, and others). In order to account for the uncertainties associated with some of the key parameters and to add robustness to our model, we have presented three different forecast scenarios, depicting conservative, base and optimistic tracks of the market’s evolution.

The research, analysis and insights presented in this report is backed by a deep understanding of insights gathered both from secondary and primary sources. The opinions and insights presented in this study were influenced by discussions conducted with several key players in this domain. The report features detailed transcripts of interviews held with the following key opinion leaders:

  1. Sam de Costa (Stabilization Projects Manager, Nova Laboratories)
  2. Manuel Leal (Business Development Director, Idifarma)
  3. Anonymous (Founder, India based Manufacturer)

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

Contents

Chapter 2  provides an executive summary of the insights captured in our research. It offers a high-level view on the likely evolution of the spray drying market in the long term.

Chapter 3  provides an introduction to the spray drying approach, including a detailed discussion on the principle / process of spray drying, highlighting the key steps associated with the process. It highlights the important applications of the technique and the various features that distinguish it from alternative drying technologies. The chapter also features a discussion on the various advantages and limitations associated with spray drying.

Chapter 4  provides an overview of the applications of spray drying in the pharmaceutical industry, from generation of extremely fine particles for pulmonary administration to large agglomerated powders for oral formulations. Specifically, the different applications discussed in the chapter include enhancement of solubility and bioavailability, formulation of inhalables, taste masking, development of controlled release formulations, and aseptic production of biopharmaceuticals.

Chapter 5  includes a comprehensive market overview, featuring information on various types of spray dryers used in the pharmaceutical industry. It provides information on their respective manufacturers (company size and year of establishment) and presents an analyses of spray dryers on the basis of inlet temperature, type of nozzle (fluid, pressure, rotary disc and others) used, size of the unit (lab, clinical and commercial), and atomizing gas (air, nitrogen and inert gases) used. Further, the chapter includes a discussion on companies that offer pharmaceutical spray drying services. It presents an analysis of various spray drying service providers on the basis of the geographical location of their facilities, scale of operation (lab, clinical and commercial) and information on cGMP statuses of their facilities.

Chapter 6  presents the key insights derived from the study. It features detailed 2X2 matrices, comparing the spray drying capabilities and the supplier power of different spray drying service providers. A similar analysis comparing the spray dryer portfolio and the establishment year of different manufacturers of spray dryers, is also included in the chapter. In addition, the chapter features a comprehensive geographical landscape analysis, which highlights the spray drying activity across the globe, in terms of presence of both manufacturers and service providers.

Chapter 7  features tabular profiles of the most active service providers ( as identified in chapter 6 ) in the pharmaceutical industry. It highlights the expertise of these players in terms of their spray drying capabilities. Each profile provides a brief overview of the company, highlighting its employee strength ( if available ), its product / service portfolio, spray dryers used ( if available ) and the key developments related to spray drying ( if available ).

Chapter 8  provides detailed profiles of the most active spray dryer manufacturers ( as identified in chapter 6 ) in the pharmaceutical industry. Each profile provides a brief overview of the company, its financial information ( if available ), its portfolio of spray dryers, recent developments, and a comprehensive future outlook.

Chapter 9  features a case study on lyophilization of biologics, the key competing technique to spray drying. The chapter elaborates on the steps involved in lyophilization, and lyophilization cycle development and optimization. It includes an exemplary list of service providers offering lyophilization services with information on location of facilities, type of drug candidates lyophilized, scale of operation and the containment systems utilized for such operations.

Chapter 10  presents a detailed analysis of the mergers and acquisitions that have taken place within this industry. The chapter highlights the information on the acquiring and the acquired company (headquarters and the ownership (public / private)), along with the year of acquisition, acquiring amount ( if available ), and the financial status of the acquired company, at the time of acquisition. It features a detailed ownership change matrix depicting the distribution of mergers and acquisitions across private firms, public firms and sole proprietorships. It also includes an evaluation of the financials of these deals (revenues of the acquired firms at the time of acquisition and their respective deal multiples).

Chapter 11  presents a comprehensive market forecast analysis, highlighting the future potential of the spray drying services market till the year 2028. The chapter also presents detailed market segmentation on the basis of geographical regions (North America, Europe, Asia Pacific and the rest of the world), type of industry (pharmaceuticals and biologics), and type of nozzles used in spray dryers (fluid nozzle, pressure nozzle, rotary disc atomizer, centrifugal nozzle and others).

Chapter 12  presents a detailed analysis capturing the key parameters and trends that are likely to influence the future of the spray drying market, under a comprehensive SWOT framework. The chapter also features a schematic Harvey ball analysis to highlight the relative impact of each SWOT parameter on the overall market.

Chapter 13  is a summary of the overall report. In this chapter, we have provided a list of the key takeaways from the report, and expressed our independent opinion related to the research and analysis described in the previous chapters.

Chapter 14  is a collection of transcripts of interviews held with key stakeholders in this market. In this chapter, we have presented the details of our conversations with Sam de Costa (Stabilisation Projects Manager, Nova Laboratories), Manuel Leal (Business Development Director, Idifarma), Anonymous (Founder, India based Manufacturer).

Chapter 15  is an appendix, which provides tabulated data and numbers for all the figures included in the report.

Chapter 16  is an appendix, which contains the list of companies and organizations mentioned in the report.

Table of Contents

1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
 
2. EXECUTIVE SUMMARY
 
3. INTRODUCTION
3.1. The Spray Drying Process
3.1.1. Feed Preparation
3.1.2. Atomization
3.1.3. Feed Drying
3.1.4. Separation of the Powder, Cooling and Packaging
 
3.2. Applications of Spray Drying
3.3. Spray Drying of Biopharmaceuticals
3.4. Alternatives to Spray Drying
3.4.1. Lyophilization
3.4.2. Spray Freeze Drying
3.4.3. Atmospheric Spray Freeze Drying
3.4.4. Vacuum Foam Drying
 
3.5. Advantages and Limitations of Spray Drying
 
4. SPRAY DRYING: KEY APPLICATIONS IN THE PHARMACEUTICAL INDUSTRY
4.1. Chapter Overview
4.2. Enhancement of Solubility and Bioavailability
4.3. Distribution of Particle Size of Inhalable Drugs
4.4. Modified Release and Taste Masking
4.5. Aseptic Production of Pharmaceuticals
 
5. PHARMACEUTICAL SPRAY DRYING: MARKET OVERVIEW
5.1. Chapter Overview
5.2. Pharmaceutical Spray Dryers: List of Manufacturers
5.2.1. Distribution by Type of Nozzles
5.2.2. Distribution by Inlet Temperature
5.2.3. Distribution by Atomizing Gas
5.2.4. Key Manufacturers
 
5.3. Pharmaceutical Spray Drying: Service Providers
5.3.1. Distribution by Scale of Operation
5.3.2. Distribution by cGMP Availability
6.3.3. Popularly Used Spray Dryers
 
5.4. Pharmaceutical Spray Drying: Companies with In-house Facilities
5.5. Pharmaceutical Spray Drying: Companies Involved in Bioavailability Enhancement
 
6. SPRAY DRYING SERVICE AND EQUIPMENT PROVIDERS: COMPETITIVE LANDSCAPE
6.1. Chapter Overview
6.2. Pharmaceutical Spray Drying Service Providers: Competitive Landscape
6.3. Pharmaceutical Spray Dryer Manufacturers: Competitive Landscape
6.4. Pharmaceutical Spray Drying: Geographical Landscape
 
7. SPRAY DRYING SERVICE PROVIDERS: COMPANY PROFILES
7.1. Chapter Overview
7.2 Ajinomoto (Omnichem)
7.3. Almac Group
7.4. Biotech Investment Group (Formex)
7.5. Catalent Pharma Solutions
7.6. Coriolis Pharma
7.7. Evotec
7.8. Fuji Chemical Industry
7.9. Hovione
7.10. Idifarma
7.11. Lonza (Capsugel / Bend Research)
7.12.Micro-Sphere
7.13. Nova Laboratories
7.14. Patheon (Agere Pharmaceuticals)
7.15. Pulse Combustion Systems
7.16. Richman Chemical
7.17. Siegfried
7.18. Upperton
 
8. SPRAY DRYER MANUFACTURERS: COMPANY PROFILES
8.1. Chapter Overview
8.2. Buchi Labortechnik
8.2.1. Company Overview
8.2.2. Financial Overview
8.2.3. Portfolio of Spray Dryers and Services
8.2.4 Recent Developments
8.2.5 Future Outlook
 
8.3. GEA Niro
8.3.1. Company Overview
8.3.2. Financial Information
8.3.3. Portfolio of Spray Dryers and Services
8.3.4. Recent Developments
8.3.5. Future Outlook
 
8.4. Hemraj India
8.4.1. Company Overview
8.4.2. Portfolio of Spray Dryers
8.4.3 Recent Developments
8.4.4 Future Outlook
 
8.5. SPX (SPX FLOW)
8.5.1. Company Overview
8.5.2. Financial Information
8.5.3. Portfolio of Spray Dryers
8.5.4. Future Outlook
 
8.6. Techni Process
8.6.1. Company Overview
8.6.2. Portfolio of Spray Dryers
8.6.3 Future Outlook
 
8.7. Labultima
8.7.1. Company Overview
8.7.2. Portfolio of Spray Dryers
8.7.3 Future Outlook
 
8.8. Other Manufacturers
8.8.1. Advanced Drying Systems
8.8.2. ProCepT
8.8.3. Raj Process Equipments
8.8.4. Spray Drying Systems (SDS)
 
9. CASE STUDY ON THE KEY COMPETING STRATEGY: LYOPHILIZATION
9.1. Chapter Overview
9.2. Historical Background
9.3. Underlying Principle
9.4. Equipment
9.5. Advantages and Disadvantages
9.6. Applications of Lyophilization
9.6.1. Pharmaceutical and Biotechnology Industry
9.6.2. Food Industry
9.6.3. Microbiology
9.6.4. Chemical Industry
9.6.5. Dairy Industry
9.6.6. Nutraceutical Industry
9.6.7. Floral Lyophilization
9.6.8. Other Applications
9.7. Lyophilization Process for Biopharmaceuticals
9.7.1. Formulation and Filling
9.7.2. Freezing
9.7.3. Primary Drying
9.7.4. Secondary Drying
9.8. Lyophilization Service Providers for Biopharmaceuticals
 
10. MERGERS AND ACQUISITIONS
10.1. Chapter Overview
10.2. Pharmaceutical Spray Drying: Mergers and Acquisitions
10.2.1. Year-wise Trend
10.2.2. Geographical Activity
10.2.3. Ownership Change Matrix
10.3. Key Acquisitions: Deal Multiples
 
11. MARKET SIZING AND FORECAST
11.1. Chapter Overview
11.2. Forecast Methodology
11.3. Pharmaceutical Spray Drying Services Market, 2018-2028 (USD Billion)
11.4. Pharmaceutical Spray Drying Services Market, 2018-2028: Distribution by Product Type (Pharmaceuticals / Biologics) (USD Billion)
11.5. Pharmaceutical Spray Drying Services Market, 2018-2028: Distribution by Region (USD Billion)
11.5.1. Pharmaceutical Spray Drying Services Market: North America (USD Billion)
11.5.2. Pharmaceutical Spray Drying Services Market: Europe (USD Billion)
11.5.3. Pharmaceutical Spray Drying Services Market: Asia Pacific and Rest of the World (USD Billion)
11.6. Pharmaceutical Spray Drying Services Market, 2018-2028: Distribution by Type of Nozzle (USD Billion)
 
12. SWOT ANALYSIS
12.1. Chapter Overview
12.2. Strengths
12.3. Weaknesses
12.4. Opportunities
12.5. Threats
12.6. Concluding Remarks
 
13. CONCLUSION
13.1. Given its Benefits Over Alternative Formulation Technologies, the Applications of Spray Drying Are Likely to Increase in the Pharmaceutical and Biotechnology Sector
13.2. Several Stakeholders with Spray Drying Capabilities Have Established their Presence Across Different Regions; North America and Europe have Emerged as Key Hubs
13.3. Players are Actively Procuring Spray Drying Facilities and Capabilities; This is Evident From the Number of Acquisitions that have Recently Taken Place
13.4 Advanced Technologies, such as Aseptic Spray Drying, Are Expected to Positively Impact the Future Adoption
13.5. Despite Various Challenges and Competition from Legacy Drying Technologies, the Market is Anticipated to Grow at an Annualized Rate of 17% Between 2018 and 2028
 

14. EXECUTIVE INSIGHTS
14.1. Chapter Overview
14.2. Idifarma, Manuel Leal, Business Development Director
14.3. Sam De Costa, Stabilisation Projects Manager, Nova Laboratories
14.4. Anonymous, Founder, Mid-sized India Based Spray Dryer Manufacturer
 
15. APPENDIX 1: TABULATED DATA
 
16. APPENDIX 2: LIST OF COMPANIES

List of Figures

Figure 3.1  Spray Drying: A Schematic View of Equipment
Figure 3.2  Spray Drying: Key Steps Involved in the Process
Figure 3.3  Spray Drying: Advantages and Limitations 
Figure 4.1 Spray Drying: Key Applications in Pharmaceutical Industry
Figure 4.2 Biopharmaceutics Classification System
Figure 4.3  Dispersion Mechanism for Inhalable Nanoparticles
Figure 5.1 Pharmaceutical Spray Dryers: Distribution by Type of Nozzles
Figure 5.2 Pharmaceutical Spray Dryers: Distribution by Inlet Temperature
Figure 5.3 Pharmaceutical Spray Dryers: Distribution by Atomizing Gas
Figure 5.4 Pharmaceutical Spray Dryers: Key Manufacturers
Figure 5.5 Pharmaceutical Spray Drying Service Providers: Distribution by Scale of Operation
Figure 5.6 Pharmaceutical Spray Drying Service Providers: Distribution by cGMP Availability
Figure 5.7 Pharmaceutical Spray Drying Service Providers: Popularly Used Spray Dryers
Figure 6.1 Pharmaceutical Spray Drying Service Providers: Competitive Landscape
Figure 6.2 Pharmaceutical Spray Dryer Manufacturers: Competitive Landscape
Figure 6.3 Pharmaceutical Spray Drying Capabilities: Geographical Landscape
Figure 8.1  Buchi: Annual Revenues, 2012- 2017 (EUR Billion)
Figure 8.2  GEA Niro: Annual Revenues, 2012- 2017 (USD Billion)
Figure 8.3  SPX: Annual Revenues, 2012- 2017 (USD Billion)
Figure 9.1  Lyophilization: Historical Timeline
Figure 9.2  Phase Diagram of Water
Figure 9.3  Sublimation of Ice Crystals
Figure 9.4  Components of a Lyophilizer
Figure 9.5  Applications of Lyophilization
Figure 9.6  Formulation and Filling of Biopharmaceuticals: Key Steps
Figure 9.7 Freezing of Biopharmaceuticals: Key Steps
Figure 10.1  Pharmaceutical Spray Drying Mergers and Acquisitions: Year-Wise Trend
Figure 10.2  Pharmaceutical Spray Drying Mergers and Acquisitions: Geographical Activity
Figure 10.3  Pharmaceutical Spray Drying Mergers and Acquisitions: Distribution by Local and International Acquisitions
Figure 10.4  Pharmaceutical Spray Drying Mergers and Acquisitions: Ownership Change Matrix
Figure 11.1  Pharmaceutical Spray Drying Services Market, 2018-2028: Base Scenario (USD Billion)
Figure 11.2  Pharmaceutical Spray Drying Services Market, 2018, 2023, 2028: Distribution by Product Type (Pharmaceuticals / Biologics), (USD Billion)
Figure 11.3  Pharmaceutical Spray Drying Services Market, 2018, 2023 and 2028:  Distribution by Region
Figure 11.5  Pharmaceutical Spray Drying Services Market, 2018-2028: North America, Base Scenario (USD Billion)
Figure 11.6 Pharmaceutical Spray Drying Services Market, 2018-2028: Europe, Base Scenario (USD Billion)
Figure 11.7  Pharmaceutical Spray Drying Services Market, 2018-2028: Asia Pacific and Rest of the World, Base Scenario (USD Billion)
Figure 11.8  Pharmaceutical Spray Drying Services Market, 2018-2028: Distribution by Type of Nozzle, Base Scenario (USD Billion)
Figure 12.1  Pharmaceutical Spray Drying Market: SWOT Analysis
Figure 12.2  Pharmaceutical Spray Drying Market: Comparison of SWOT Factors, Harvey Ball Analysis
Figure 13.1  Pharmaceutical Spray Drying Services Market: 2018, 2022 and 2028 (USD Billion)

List of Tables

Table 3.1  Types of Atomizers Used in Spray Dryers
Table 3.2  Spray Dryers: Modes of Operation
Table 3.3  Comparison of Spray Drying and Lyophilization
Table 3.4  Comparison of Spray Drying and Spray Freeze Drying
Table 4.1  Examples of Spray Dried Drugs for Improved Solubility and Bioavailability
Table 4.2 Examples of Spray Dried Inhalation Drugs
Table 4.3 Polymers Used for Drug Encapsulation
Table 4.4 Polymers Used for Controlled and Immediate Release
Table 4.5 Examples of Spray Dried Drugs for Taste Masking
Table 5.1  Pharmaceutical Spray Drying Service Providers: Capabilities
Table 5.2 Pharmaceutical Spray Dryer Manufacturers: Competitive Landscape
Table 5.3 Pharmaceutical Spray Drying Manufacturers and Service Providers: Geographical Distribution
Table 6.1 Pharmaceutical Spray Dryers: List of Manufacturers
Table 6.2 Pharmaceutical Spray Drying: List of Service Providers
Table 6.3 Pharmaceutical Spray Drying Service Providers: Scale of Operation
Table 6.4 Pharmaceutical Spray Drying: Companies with In-house Facilities
Table 6.5 Pharmaceutical Spray Drying: Companies Involved in Bioavailability Enhancement
Table 7.1  Pharmaceutical Spray Drying Service Providers: List of Companies Profiled
Table 7.2  Company Profile: Ajinomoto (Omnichem)
Table 7.3 Company Profile: Almac Group
Table 7.4 Company Profile: Biotech Investment Group (Formex)
Table 7.5 Company Profile: Catalent Pharma Solutions
Table 7.6  Company Profile: Coriolis Pharma
Table 7.7  Company Profile: Evotec (Aptuit / Kuecept)
Table 7.8  Company Profile: Fuji Chemical Industry
Table 7.9  Company Profile: Hovione
Table 7.10 Company Profile: Idifarma
Table 7.11  Company Profile: Lonza (Capsugel / Bend Research)
Table 7.12  Company Profile: Micro-Sphere
Table 7.13  Company Profile: Nova Laboratories
Table 7.14  Company Profile: Patheon (Agere Pharmaceuticals)
Table 7.15  Company Profile: Pulse Combustion Systems
Table 7.16 Company Profile: Richman Chemical
Table 7.17  Company Profile: Siegfried
Table 7.18 Company Profile: Upperton
Table 8.1  Pharmaceutical Spray Dryer Manufacturers: List of Companies Profiled
Table 8.2  Buchi Labortechnik Spray Dryers Portfolio: Key Features
Table 8.3  Buchi Spray Dryers: Clients
Table 8.4  GEA Spray Dryers Portfolio: Key Features
Table 8.5  GEA Spay Drying Services: Clients
Table 8.6  Hemraj India Spray Dryers Portfolio: Key Features
Table 8.7  Hemraj India: Clients
Table 8.8  SPX Spray Dryers Portfolio: Key Features
Table 8.9  SPX: MicraSpray Dryer Models
Table 8.10  Labultima Portfolio: Key Features
Table 8.11  Labultima Spay Drying Services: Clients
Table 8.12  Advanced Drying Systems Spray Dryers Portfolio: Key Features
Table 8.13  SDS Spray Dryers Portfolio: Key Features
Table 9.1  Lyophilization: Advantages and Disadvantages
Table 9.2  List of Lyophilization Service Providers for Biopharmaceuticals 
Table 9.3  Lyophilization Service Providers for Biopharmaceuticals: Type of Biopharmaceuticals Lyophilized
Table 9.4  Lyophilization Service Providers for Biopharmaceuticals: Scale of Operation 
Table 10.1  Pharmaceutical Spray Drying: List of Mergers and Acquisitions
Table 10.2  Pharmaceutical Spray Drying: Deal Multiples of Mergers and Acquisitions
Table 15.1 Pharmaceutical Spray Dryers: Distribution by Type of Nozzles
Table 15.2  Pharmaceutical Spray Dryers: Distribution by Inlet Temperature
Table 15.3  Pharmaceutical Spray Dryers: Distribution by Atomizing Gas
Table 15.4 Pharmaceutical Spray Dryers: Key Manufacturers
Table 15.5  Pharmaceutical Spray Drying Service Providers: Distribution by Scale of Operation
Table 15.6  Pharmaceutical Spray Drying Service Providers: Distribution by cGMP Availability
Table 15.7  Pharmaceutical Spray Drying Service Providers: Popularly Used Spray Dryers
Table 15.8 Buchi: Annual Revenues, 2012-2017 (EUR Billion)
Table 15.9  GEA: Annual Revenues, 2012- 2017 (EUR Billion)
Table 15.10  SPX: Annual Revenues, 2012- 2017 (USD Billion)
Table 15.11  Pharmaceutical Spray Drying Mergers and Acquisitions: Year-Wise Trend
Table 15.12  Pharmaceutical Spray Drying Mergers and Acquisitions: Key Geographical Regions
Table 15.13  Pharmaceutical Spray Drying Services Market, 2018, 2023, 2028: Distribution by Product Type (Pharmaceuticals / Biologics), (USD Billion)
Table 15.14  Pharmaceutical Spray Drying Services Market, 2018, 2023 and 2028:  Distribution by Region (USD Billion)
Table 15.15 Pharmaceutical Spray Drying Services Market, 2018-2028: North America, Conservative Scenario (USD Billion)
Table 15.16  Pharmaceutical Spray Drying Services Market, 2018-2028: North America, Base Scenario (USD Billion)
Table 15.17 Pharmaceutical Spray Drying Services Market, 2018-2028: North America, Optimistic Scenario (USD Billion)
Table 15.18  Pharmaceutical Spray Drying Services Market, 2018-2028: Europe, Conservative Scenario (USD Billion)
Table 15.19  Pharmaceutical Spray Drying Services Market, 2018-2028: Europe, Base Scenario (USD Billion)
Table 15.20 Pharmaceutical Spray Drying Services Market, 2018-2028: Europe, Optimistic Scenario (USD Billion)
Table 15.21 Pharmaceutical Spray Drying Services Market, 2018-2028: Asia Pacific and Rest of the World, Conservative Scenario (USD Billion)
Table 15.22 Pharmaceutical Spray Drying Services Market, 2018-2028: Asia Pacific and Rest of the World, Base Scenario (USD Billion)
Table 15.23 Pharmaceutical Spray Drying Services Market, 2018-2028: Asia Pacific and Rest of the World, Optimistic Scenario (USD Billion)
Table 15.24 Pharmaceutical Spray Drying Services Market, 2018-2028: Distribution by Type of Nozzle (USD Billion)
Table 15.25 Pharmaceutical Spray Drying Services Market: 2018, 2022 and 2028 (USD Billion)Figure 3.1  Spray Drying: A Schematic View of Equipment

Listed Companies

The following companies and organizations have been mentioned in the report:Acmefil Engineering Systems

  1. Acmefil Engineering Systems
  2. Advanced Drying Systems
  3. Aesica Pharmaceuticals
  4. Agere Pharmaceuticals
  5. Aizant Drug Research Solutions
  6. Ajinomoto
  7. Albion Manufacturing
  8. Alembic Pharmaceuticals 
  9. Almac Group
  10. Althea Technologies
  11. Amatsigroup
  12. AMRI 
  13. Anhydro
  14. Anteco Pharma
  15. Aptuit
  16. Aridis Pharmaceuticals
  17. Arrake
  18. Ascendia Pharmaceuticals
  19. Ashland Specialty Ingredients
  20. Astron Research
  21. Axcellerate Pharma
  22. Balchem
  23. BASF Pharma Solutions
  24. Baxter
  25. BEC Chemicals
  26. Bend Research
  27. Berkshire Sterile Manufacturing
  28. BETE Fog Nozzle
  29. Bharat Serum and Vaccines 
  30. Bio-Botanica
  31. Biocon 
  32. BioConnection
  33. BioDuro
  34. Biopharma Technology
  35. Biotech Investment Group 
  36. BioXcellence
  37. BioZed Engineering
  38. Birla Institute of Technology and Science 
  39. Boehringer Ingelheim
  40. Botanic Innovations
  41. Bovogen Biologicals
  42. Büchi Labortechnik 
  43. Capsugel
  44. Catalent Pharma Solutions
  45. CEPiA Sanofi
  46. ChangZhou Lemar Drying Engineering
  47. CinnaGen
  48. Cipla 
  49. Claris Lifesciences
  50. Consort Medical
  51. Cook Pharmica
  52. Coriolis Pharma
  53. DisperSol Technologies
  54. Dr.Reddy's Laboratories
  55. Dry Tech India 
  56. Drytec Contract Processing
  57. Earthrise Nutritionals 
  58. East India Pharmaceutical
  59. Eli Lilly
  60. Emergent BioSolutions
  61. European SprayDry Technologies
  62. Eurotherm
  63. Evonik Industries 
  64. Evotec
  65. Exquiron 
  66. FAMAR 
  67. FDC
  68. Formex
  69. Formurex
  70. Foundation for Revitalisation of Local Health Traditions
  71. Fuji Chemical Industries
  72. G-Con Manufacturing
  73. GEA Niro
  74. General Spray Drying Services
  75. Gen-Plus
  76. GlaxoSmithKline
  77. Glenmark Pharmaceuticals
  78. Green Ridge Consulting
  79. Hemraj 
  80. Hindustan Unilever
  81. Hovione
  82. Idifarma Desarrollo Farmacéutico
  83. Indiana Group 
  84. Indofil Industries
  85. Intas Pharmaceuticals
  86. International Specialty Products
  87. Intran Technologies 
  88. Iran Panam
  89. Italian Ceram
  90. Janssen Pharmaceuticals 
  91. Jetpharma
  92. Jay Instruments and Systems 
  93. Jubilant Life Sciences
  94. Juniper Pharmaceuticals
  95. Kelkar Education Trust's Scientific Research Centre
  96. Kuecept
  97. L A B International
  98. Labplant 
  99. Labultima Process Technologies
  100. Legacy BioDesign
  101. Lesaffre Ingredients Services
  102. LEUKOCARE 
  103. Lipomize
  104. Liquidia Technologies
  105. Lonza 
  106. LSNE Contract Manufacturing
  107. Lubrizol 
  108. Lupin Pharmaceuticals 
  109. LYOCONTRACT
  110. Lyofal
  111. Lyophilization Technology
  112. Medreich 
  113. Meggle Pharma
  114. Metrics Contract Services
  115. Microchem Silliker
  116. Micromacinazione
  117. Micro-Sphere 
  118. MINAKEM
  119. Juniper Pharmaceuticals
  120. Muskat-Plyus
  121. Mycenax Biotech
  122. NanoMaterials Technology
  123. New AVM Systech
  124. North Star Processing
  125. Norwich Pharma Services
  126. Nova Laboratories
  127. Novartis
  128. Ohkawara Kakohki
  129. Omega Flavour Technology 
  130. OmniActive Health Technologies
  131. OmniChem
  132. Orbite Technologies 
  133. PacMoore
  134. Panacea Biotec
  135. Particle Sciences
  136. PATH
  137. Patheon 
  138. Pawana Engineering Projects
  139. BV Patel Pharmaceutical Education and Research Development Centre
  140. Pfizer
  141. Pharma Spray Drying
  142. Pharmachem Laboratories
  143. PharmaForm
  144. Pharmatek Laboratories
  145. Pharmaterials
  146. Piramal Pharma Solutions
  147. Plant Lipids
  148. Proalgen Biotech
  149. ProCepT
  150. Pulse Combustion Systems
  151. Quality Bioresources
  152. Quay Pharma
  153. Quest Life Sciences
  154. Quotient Sciences 
  155. Raj Process Equipments And Systems
  156. Ranbaxy Laboratories
  157. Reliance Industries 
  158. Richman Chemical 
  159. Roche
  160. Samsung BioLogics
  161. Sandoz 
  162. Siegfried
  163. Shungeng Drying Equipment 
  164. Siam Bioscience
  165. SiccaDania
  166. Solvias
  167. Sono-Tek 
  168. Spray Drying Systems
  169. Spray-Tek
  170. SPX FLOW
  171. StemProtein
  172. Sulphur Mills 
  173. Summit Custom Spray Drying
  174. Sun Pharmaceutical Industries
  175. Symbiotec Pharmalab 
  176. Synthite Industrial Chemicals 
  177. Takeda Pharmaceutical
  178. Techni Process
  179. Technical University of Denmark
  180. Tecpro Australia
  181. TEFIC BIOTECH
  182. Temmler
  183. The Himalaya Drug Company
  184. Themis Laboratories 
  185. Toption Instrument 
  186. Torrent Pharmaceuticals
  187. UFAG LABORATORIEN 
  188. Unitop Chemicals 
  189. Upperton Pharma Solutions 
  190. USV
  191. Vectura Group 
  192. Veer Narmad South Gujarat University
  193. Vetter Pharma
  194. Wannemacher Total Logistics
  195. Wockhardt Research Centre
  196. WuXi AppTec
  197. XEDEV
  198. Xi'an Hongchang Pharmaceuticals
  199. Zydus Cadila
     

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