Top DNA Synthesis Companies

Published: April 2024


Driven by numerous advantages of enzymatic DNA synthesis platforms, including greater accessibility and potential to increase length of DNA fragment, DNA synthesis companies are actively looking for efficient technologies to provide unmatched precision, scalability and speed. We analyzed over 65 DNA synthesis companies that are engaged in offering technologies and services related to DNA synthesis. In this article, discover 7 top DNA synthesis companies and their capabilities in this industry.


The concept of artificial DNA synthesis has a far-reaching impact across multiple areas, including genetic circuit design, genetic engineering, genome synthesis, diagnosis and treatment of genetic diseases. It is worth mentioning that synthetic biology has emerged as a disruptive technology, capable of delivering new solutions to global healthcare, agriculture, manufacturing and environmental challenges. Given the recent advances in the field of molecular biology, the development of automatic robust chemistries for chemical synthesis of DNA has contributed towards the engineering of biological systems and study genome in a high throughput manner. Synthetic biology, when combined with sequence data generated by Next Generation Sequencing (NGS) technology, allows analysis of RNA and DNA levels to study the genetic variations associated with the disease or other biological phenomena.

In the recent years, the spread of COVID-19 has given a significant boost to the development of DNA and RNA-based vaccines to induce potent immune responses in the patients. Moreover, customized DNA and RNA synthesis coupled with CRISPR technologies for gene editing and other synthetic biology technologies have demonstrated the potential to change the standard of care for a wide range of disease indications. DNA synthesis technologies not only facilitate parallelized synthesis of DNA but also provide unmatched precision, scalability and speed. Several companies have developed proprietary enzymatic DNA synthesis platforms offering distinct advantages (such as the potential to increase length of DNA fragment, greater accessibility and convenience) over conventional DNA synthesis methods. Furthermore, a significant proportion of medical researchers and drug developers prefer to outsource DNA synthesis and replication operations to third party platforms / service providers who claim to provide expertise in DNA synthesis and production. Given the rising need for DNA across a wide range of applications, we are led to believe that the DNA synthesis and DNA replication platforms and services industry is likely to witness noteworthy market growth during the forecast period.

Roots Analysis has conducted an exhaustive study on DNA Synthesis Market featuring the current market landscape and future opportunity for the DNA synthesis companies that are engaged in the development of DNA synthesis technologies and offer services in this domain, over a span of 12 years.

Table of Contents

Below, we have listed (in alphabetical order), the top 7 DNA synthesis companies.

  1. Ajinomoto Bio-Pharma Services
  2. ATUM
  3. DNA Script
  4. Eurofins Genomics
  5. Gene Universal
  6. GenScript
  7. Synbio Technologies

Top 7 DNA Synthesis Companies

Interested in exploring all 65+ DNA synthesis companies and their recent initiatives?

Discover Below the Details on 7 Top DNA Synthesis Companies

Let us deep dive to understand the activity of the 7 top DNA synthesis companies (shortlisted on the basis of company size ((large (more than 1,000 employees) and mid-sized (51 to 500 employees)) that offer technologies and services related to synthesis of DNA. It is essential to note that the selection of top players can differ substantially according to the defined criteria.

With Operations Across 35 Countries and More than 100 Manufacturing Facilities, Ajinomoto Bio-Pharma Services is Engaged in Offering Services for Oligonucleotides Synthesis

1. Ajinomoto Bio-Pharma Services

Ajinomoto Bio-Pharma Services is a US-based contract development and manufacturing organization, that offers customized services for the synthesis of high-quality oligonucleotides and peptides. The service offerings of the company include oligonucleotide synthesis, protein expression, antibody drug conjugates development, bio catalysis and continuous flow manufacturing. It is worth noting that, the company employs AJIPHASE® technology and fast solid phase synthesis for the large-scale manufacturing of DNA / RNA oligonucleotides, phosphorodiamidate morpholino oligonucleotides (PMOs) and long chain peptides.

Ajinomoto Bio-Pharma Services: Company Details

Key Parameters Description
Company Logo Ajinomoto Bio-Pharma Services, Top DNA Synthesis Companies
Year of Establisment   1997
Number of Employees  1,001-5000
Headquarter Ajinomoto Bio-Pharma Services, Headquarter


Ajinomoto Bio-Pharma Services: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name AJIPHASE® Synthesis Technology
Method of DNA Synthesis 
  • Chemical Synthesis
  • Enzymatic Synthesis
Cusotm Synthsis Yes
Application Areas
  • Research and Development
  • Diagnostics


Recent Initiatives by Ajinomoto Bio-Pharma Services Focusing on DNA Synthesis Domain: In February 2023, the company announced the development of highly functional ancestral RNA ligase for the formation of double strand oligonucleotide with high productivity.

Further details on recent initiatives taken by Ajinomoto Bio-Pharma Services as well as other DNA synthesis companies have been provided in detail in the report.

ATUM offers Comprehensive, Reliable and High-quality Custom Solutions for Rapid, Reliable and Accurate Synthesis of DNA Solutions

2. ATUM

ATUM (previously known as DNA2.0) is a leading biotechnology firm engaged in offering synthetic biology solutions for over a decade. The company claims to have expertise in the field of molecular biology, bioinformatics, technology development and research leadership. ATUM takes advantage of the dependence of biological activity on well-designed sequences. The company also claims that its tools and solutions are fueling the transformation of biology from a discovery science to an engineering discipline.  It is important to mention that ATUM offers GeneGPS® platforms which has applications in research and development and gene optimization.

ATUM: Company Details

Key Parameters Description
Company Logo ATUM, Top DNA Synthesis Companies
Year of Establisment   2003
Number of Employees  51-200
Headquarter ATUM, Headquarter


ATUM: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name GeneGPS®
Synthetic DNA Fragment Length  1kb - 3kb
Cusotm Synthsis Yes
Application Areas Research and Development 


Recent Initiatives by ATUM Focusing on DNA Synthesis Domain: The company offers a variety of tools, including gene design, optimization and synthesis, expression vectors, and platforms for protein production. It is worth mentioning that the company has forged a patent licensing agreement with Thermo Fisher Scientific in order to provide the latter company access to its gene design platform for manipulation and validation of genetic sequences.

Further details on recent initiatives taken by ATUM as well as other DNA synthesis companies have been provided in detail in the report.

Leveraging its DNA Synthesis Technology, DNA Script Claims to Revolutionize Enzyme-based DNA Synthesis

3. DNA Scirpt

DNA Script is a biotechnology company that has made a benchtop DNA printer- SYNTAX , by combining enzyme engineering, surface and nucleotide chemistry. The company claims to engineer biology in order to accelerate in life sciences and human health. DNA Script works with enzymatic DNA synthesis technology for various diagnostic applications. The company believes that with this technology they can expedite workflows, enabling life-saving vaccines to reach communities faster. In fact, the company claims that the use of primers produced with DNA Script's novel Enzymatic DNA Synthesis (EDS) technology for whole-genome amplicon sequencing and phylogenetic analysis of SARS-CoV-2 performed comparably to primers sourced from commercial suppliers as their EDS technology enabled broad-based, rapid access to synthetic DNA, thereby, accelerating the pace of iteration and innovation in the life sciences.

DNA Script: Company Details

Key Parameters Description
Company Logo DNA Script, Top DNA Synthesis Companies
Year of Establisment   2014
Number of Employees  51-200
Headquarter DNA Script, Headquarter


DNA Script: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name Enzymatic DNA Synthesis (EDS)
Method of DNA Synthesis  Enzymatic Synthesis
Cusotm Synthsis No
Application Areas Diagnostics


Recent Initiatives by DNA Script in DNA Synthesis Domain: In May 2023, the company announced the commercial availability of the fully automated SYNTAX™ DNA printing platform.

Further details on recent initiatives taken by DNA Script as well as other DNA synthesis companies have been provided in detail in the report.

Eurofins Genomics is Committed to Offering Best Practice Solutions and Versatile Concepts to its Global Network of Clients

4. Eurofins Genomics

Eurofins Genomics is a Europe-based company that claims to provide genome services for next generation sequencing, genotyping, gene expression, custom DNA sequencing, oligonucleotides, siRNA and gene synthesis. The firm also provides applications in pharma, diagnostics, agriculture, food, biotechnology and research. Additionally, with the help of the international network of companies, Eurofins claims to have expertise in genomic services, forensics, agro-science, pharmaceutical, environmental, food and feed testing. The organization has also established an outstanding team of experts with a broad range of technologies. Eurofins Genomics is globally known for its customized technologies in the life science industries and academic research institutions.

Eurofins Genomics: Company Overview

Key Parameters Description
Company Logo Eurofins Genomics, Top DNA Synthesis Companies
Year of Establisment   1990
Number of Employees  201-500
Headquarter Eurofins Genomics, Headquarter


Eurofins Genomics: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name Eurofins Genomics' DNA Synthesis Technology


Recent Initiatives by Eurofins Genomics Focusing on DNA Synthesis Domain: Based on its technical capabilities, it strives to always provide premium products and professional services. The company offers a detailed, reliable and high-quality DNA synthetic technology. Additionally, in 2019, the firm acquired Blue Heron Biotech with an aim to expand gene synthesis capabilities.

Further details on recent initiatives taken by Eurofins Genomics as well as other DNA synthesis companies have been provided in detail in the report.

Gene Universal Aims to Achieve the Prospects of Making Research in Life Sciences Efficient in a Cost-Effective Manner

5. Gene Universal

Gene Universal is a company located in Delaware, US that provides services in the field of gene synthesis and synthetic biology. It is also well known in the field of genetic engineering and biosystem engineering, The company aims to provide cost-effective services and products to accelerate the global research in drug discovery, biology optimization, food and agriculture with unparalleled customized service and fast delivery time. The firm has developed a software with the help of bioinformatic tools which helps to design and optimize complex gene libraries and genetic systems. Further, the company has also developed a variety of recombinant protein platforms, based on bacterial, mammalian, yeast, insect expression and bacillus subtilis expression systems.

Gene Universal: Company Overview

Key Parameters Description
Company Logo Gene Universal, Top DNA Synthesis Companies
Number of Employees  51-200
Headquarter Gene Universal, Headquarter


Gene Universal: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name Gene Universal's DNA Synthesis Technology
Synthetic DNA Fragment Length  150-5,000bp
Cusotm Synthsis Yes
Application Areas Research and Development


Recent Initiatives by Gene Universal Focusing on DNA Synthesis Domain: The firm is engaged in the development of its DNA synthesis technology and offers affiliated services for research, diagnostic and therapeutic purposes. The company claims to possess a vast range of capabilities, which are dedicated to high quality DNA synthesis for its global clientele.

Further details on recent initiatives taken by Gene Universal as well as other DNA synthesis companies have been provided in detail in the report.

Strengthened by its Solid DNA Synthesis Technology, GenScript Envisions To Pioneer in the Field of Biotechnology

6. GenScript

GenScript is a leading biotechnology company focused on providing DNA synthesis technology services. The firm primarily operates through four segments, namely life science services and products, biologics development services, industrial synthetic biology products, and cell therapy. It is important to mention that GenScript claims to be widely known for its gene synthesis capabilities around the world. The company claims that they provide cost effective gene synthesis technology which can be used to obtain customized DNA constructs. The company’s second platform gene on demand has applications in diagnostics.

GenScript: Company Overview

Key Parameters Description
Company Logo GenScript, Top DNA Synthesis Companies
Year of Establisment   2002
Number of Employees  1,001-5,000
Headquarter GenScript, Headquarter


GenScript: Technology / Service Portfolio for DNA Synthesis

Key Parameters Description
Technology Name
  • GenScript's DNA Synthesis Technology
  • Gene-on-Demand® Technology Platform
Synthetic DNA Fragment Length  
  • GenScript's DNA Synthesis Technology: 100-800 bp 
  • Gene-on-Demand® Technology Platform: 0-30,000 bp
Cusotm Synthsis Yes
Application Areas
  • Therapeutics
  • Diagnostics


Recent Initiatives by GenScript Focusing on DNA Synthesis Domain: In July 2023, the company announced the expansion of its facility in China for the manufacturing of cGMP sgRNA and non-viral DNA payload.

Further details on recent initiatives taken by GenScript as well as other DNA synthesis companies have been provided in detail in the report.

Synbio Technologies Operates as a One-stop Shop to Satisfy the DNA Manufacturing Needs of its Customers

7. Synbio Technologies

Founded in 2013, Synbio Technologies aims to empower scientific discoveries and drug innovation by providing the most advanced and cost-effective DNA technology platforms. The company has developed a full range of DNA sequencing, DNA synthesis, and DNA engineering capabilities to deliver suitable solutions globally to researchers for various applications, including diagnostic DNA probes, precision medicine, protein production, antibody discovery, vaccine development and novel enzymes. In addition, the company has established a chip-based DNA synthesis platform Syno® 3.0 which helps to generate thousands of sequences on a single chip. The company claims that their technology helps users to generate multiple sequences with high accuracy

Synbio Technologies: Company Details

Key Parameters Description
Company Logo Synbio Technologies, Top DNA Synthesis Companies
Year of Establisment   2013
Number of Employees  51-200
Headquarter Synbio Technologies, Headquarter


Synbio Technologies: Technology / Service Portfolio for DNA Synthesis

Key Parameters Details
Technology Name Syno® 3.0 Platform
Method of DNA Synthesis   Chemical Synthesis
Synthetic DNA Fragment Length  More than 6,000 bp


Recent Initiatives by Synbio Technologies Focusing on DNA Synthesis Domain: The company claims to have developed a detailed platform oligo synthesis, gene synthesis (fragment and clonal genes) and next-generation high-throughput gene synthesis. It also claims to synthesize over 3 million base pairs of gene sequences, each month, for a wide range of applications, including protein production, antibody discovery, genetically engineered vaccine, molecular breeding and biofuel.

Further details on recent initiatives taken by Synbio Technologies as well as other DNA synthesis companies have been provided in detail in the report.

What About the Other DNA Synthesis Companies Around the World?

The above presentation features seven top DNA synthesis companies selected from a pool of over 65 players that we have compiled. If you're interested, you can download the Sample Report on this topic by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com.

About Author

Prachi_Bhalla

Prachi holds an M.Tech degree in Biotechnology from Indian Institute of Technology, Guwahati and B.E. degree in Biotechnology from Panjab University, Chandigarh. Upon completing her postgraduate studies, she embarked on her research career by securing the position of Senior Research Fellow at PGIMER, Chandigarh. In her more than two years of scientific career, she honed her skills in the field of cell and molecular biology, pathology and organic chemistry. Prachi has over two years of remarkable experience in the business research and consulting domain. She is equipped with the distinctive skill set to thrive and contribute immensely to the development of syndicate reports and assignments pertaining to the pharmaceutical and biotechnology industry. She has persistently sought to present impactful, critical insights to the clients through several drug-based, product-based, technology-based and service-based research reports.

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