Antibody Purification Services Market

Global Antibody Purification Services Market by Company Size, Type of Antibody, Purification Method, End User and by Key Geographical Regions (North America, Europe, Asia-Pacific, Latin America and Middle-East and North Africa), 2021-2030

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Antibody Purification Services Market Overview

The global antibody purification services market is projected to be worth $2.02 billion in 2030, representing a CAGR of nearly 10%, between 2020 and 2030. Orthoclone OKT3® was the first monoclonal antibody-based drug (approved in 1986). As of today, more than 100 such products are available for therapeutic use across different geographies. Recently, Margenza™ (December 2020), Danyelza® (November 2020), Adakveo® (November 2019), Beovu® (October 2019), SKYRIZI™ (April 2019) and EVENITY™ (April 2019), were approved by the USFDA. Owing to their specificity for a target biomolecule (antigen) and favorable safety profile (compared to small molecule drugs), antibody-based interventions presently make up the largest class of biologic drugs. This trend is unlikely to change as multiple advanced variants of these drugs, such as bispecific antibodies and antibody fragments-based products, have been developed and several pharmacological leads based on these relatively novel constructs, are under evaluation. However, as is the case with all biologics, the production of antibodies is also a complex process. Specifically, antibody purification, which is one of the most crucial steps downstream of the manufacturing process, is a cost intensive operation. The investment of both effort and capital at this stage of production is justified because any impurity, or unwanted antibody molecule, poses a serious threat to not only therapeutic efficacy but also to the safety of patients. A variety of physiochemical approaches, including ammonium sulphate precipitation, hydrophobic interaction chromatography, ion-exchange chromatography and size exclusion chromatography techniques, are used to purify antibodies. 

This image highlights the context of Antibody Purification Market This image provides list of Antibody Purification Service Providers in Antibody Purification Market This image presents the overall market landscape of Antibody Purification Market

With the surge in demand for antibodies across research, diagnostic and therapeutic applications, there is now an urgent, parallel need to optimize production throughput. In this context, the purification aspect needs to be handled with extra caution, considering the dangers associated with contaminated medical products. Owing to prohibitive capital investments on purification infrastructure and the required expertise, not all therapy developers are able to establish in-house capabilities, especially at the larger (clinical and commercial) scales. Outsourcing is, therefore, a widely used operational model in this industry. The antibody purification services market today has evolved into a competitive domain, featuring the presence of start-ups, mid-sized companies and several established firms, some of which claim to offer end-to-end downstream processing solutions, as well. Moreover, such service-focused companies generally ensure that they have the latest upgrades in equipment and infrastructure, in order to differentiate themselves from the contemporary competition. Given the growing trend of outsourcing in the healthcare industry and the ongoing efforts of service providers to further improve / expand their respective portfolios, we believe the antibody purification services market is likely to witness a steady market growth during the forecast period.

Recent Developments in Global Antibody Purification Services Market:

Several recent developments have taken place in the field of global antibody purification services market. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.

  • In August 2023, Cambridge Healthtech Institute organized 9th annual conference focused on advances in purification and recovery of antibodies, complex biologics and macromolecules entities.

Scope of the Report

The "Global Antibody Purification Services Market, 2020-2030" market report features an extensive study on the current market landscape, market size, market share, market forecast, market outlook and future opportunities of the antibody purification services market. The market research report underlines an in-depth analysis of the purification services for antibodies offered by service providers, which are intended for use in various R&D and / or therapeutic purposes.

This image represents the geographical distribution of the players engaged in Antibody Purification Market This image highlights the competitiveness analysis, highlighting prominent antibody purification service providers in Antibody Purification Market This image provides an insightful regional capability assessment framework in Antibody Purification Market

In addition to other elements, market research report includes:

  • A detailed review of the overall landscape of the antibody purification services market, highlighting the contributions of service providers, along with the information on year of establishment, company size, location of headquarters, sources of antibodies and type of antibody (monoclonal, polyclonal and others), type of purification method (physio chemical, class specific and antigen affinity purification), application area (diagnostics, therapeutics and research) and end user (hospitals and clinics, industry and research institutes). 
  • A company competitiveness analysis, highlighting prominent antibody purification service providers based in different regions, taking into consideration supplier strength (in terms of experience and size of the service provider), and portfolio specifications (sources of antibody, type of antibody, type of purification method, application and end user).
  • Elaborate profiles of antibody purification service providers. Each company profile features a brief overview of the company, its financial information (if available), antibody purification service portfolio and an informed future outlook.
  • An insightful regional capability assessment framework, highlighting the comparison of the capabilities of service providers (based on source of antibody, purification method, application area, purification demand and the market size) across different geographies.
  • Informed estimates of the annual commercial and clinical demand for antibodies, based on various relevant parameters, such as target patient population, dosing frequency and dose strength.
  • A case study on market landscape of companies, offering contract services for the manufacturing of antibodies, including information on year of establishment, company size, scale of operation (preclinical, clinical and commercial), location of headquarters, number of manufacturing facilities and location of these facilities, type of antibody manufactured (monoclonal antibodies, bispecific antibodies and polyclonal antibodies), type of expression systems used (mammalian, microbial and others), and affiliations to regulatory agencies

The key objective of antibody purification services market report is to provide a detailed market analysis in order to estimate the existing market size, market value, statistics and future opportunity for antibody purification services market during the forecast period. Based on multiple parameters, such as projected growth of overall antibody-based products market, cost of goods sold and direct manufacturing costs, we have developed informed estimates on the financial evolution of the market over the forecast period 2020-2030. The market report also provides details on the likely distribution of the current and forecasted opportunity across [A] company size (small, mid-sized and large / very large), [B] type of  antibody (monoclonal, polyclonal and others), [C] type of purification method (physio chemical, class specific and antigen affinity purification), [D] end user (pharmaceutical and biotechnology companies, and diagnostic laboratories) and [E] key geographies (North America, Europe, Asia Pacific, Middle East and North Africa (MENA), and Latin America (LATAM)).
To account for the uncertainties associated with this industry and to add robustness to our model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic tracks of the market's evolution.

This image provides list of Antibody Contract Manufacturers in Antibody Purification Market This image provides an estimate the existing market size and the future opportunities within the Antibody Purification Market This image highlights the market segments of Antibody Purification Market

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this market research report are in USD, unless otherwise specified.

Key Questions Answered

  • Who are the leading players offering antibody purification services?
  • What is the current geographical distribution of antibody purification service providers?
  • What are the common purification methods, end users and application areas offered by the service providers?
  • What are the key factors that are likely to influence the evolution of this market?
  • What is the likely demand in the antibody purification services domain?
  • How is the current and future opportunity likely to be distributed across key market segments?
  • What are the anticipated future trends in antibody purification services market?

Frequently Asked Questions

Question 1: What is antibody purification?

Answer: Antibody purification refers to the enrichment and isolation of antibodies from serum, or cell culture supernatant.

Question 2: How big is the antibody purification market?

Answer: The antibody purification market size for service providers is estimated to be worth $2.02 billion in 2030.

Question 3: What is the projected market growth of the antibody purification market?

Answer: The antibody purification market is expected to grow at compounded annual growth rate (CAGR) of 10% during the forecast period 2021 – 2030.

Question 4: Who are the leading service providers in the antibody purification market?

Answer: Examples of key service providers engaged in antibody purification market (which have also been profiled in this market report; the complete list of companies is available in the full report) include Antibody Research, Bio-synthesis, Genscript Biotech, ProSci, QED Bioscience, SouthernBiotech, Thermo Fisher Scientific, Virusys, 2BScientific, BBI Solutions, Covalab, RD-Biotech, Allele Life Sciences, Detai Bio-Tech and Syngene.

Question 5: What is the current commercial and clinical demand for antibodies globally?

Answer: Currently, over 3,200 Kg is the commercial and clinical demand for antibodies globally.

Question 6: How many service providers are currently engaged in the antibody purification market?

Answer: Presently, over 200 service providers are engaged in the antibody purification market, offering capabilities to purify antibodies and associated products.

Question 7: What is the projected net worth of antibody based drugs market?

Answer: Currently over USD 125 billion is the projected net worth of the antibody based drugs market.

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