Bioreactors and Fermenters Market

Global Bioreactors and Fermenters Market: Distribution by Type of Product, Fabrication Material, Type of Bioprocess, Type of Biologics, and Key Geographical Regions: Industry Trends and Global Forecasts, 2023-2035

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Report Description

Since their introduction in 1982, biologics have gained popularity owing to their therapeutic efficacy, favorable safety profiles and ability to treat a wide variety of disease indications, which are otherwise hard to treat. In fact, in the past two decades, over 170 biopharmaceuticals have already been granted approval by the FDA and over 7,500 biological interventions are under evaluation in clinical trials. It is a well-known fact that the commercial and clinical-scale manufacturing of such complex biomolecules require highly specialized bioprocessing equipment to facilitate the maintenance of ideal conditions, such as optimal temperature, pH, dissolved oxygen, fluid delivery, and other critical process parameters that are essential for steady cell growth. Bioreactors are capable of providing such optimal conditions and are critical to the upstream biomanufacturing process. These systems are designed to increase the concentration of viable cells, thereby enabling the production of large amounts of recombinant proteins, such as vaccines, fusion proteins, antibodies and enzymes. Apart from producing conventional therapeutic proteins, bioreactors can also be used to produce advanced medicinal products (ATMPs), namely cell-based and oligonucleotide-based therapies, retroviral vectors for gene therapy and cellular components of three-dimensional tissue / artificial organs. In contrast to bioreactors, fermenters are used for the anaerobic cultivation of microbial (fungal or bacterial) cell populations to produce biologics that do not require significant post translational modifications. It is worth highlighting that the use of fermenters for the manufacturing of bioproducts provides faster development, higher yields and quality, reduced variation between batches, better scalability, and lower production costs, in comparison to the biomanufacturing carried out in bioreactors.

Key Market Insights

The Global Bioreactors and Fermenters Market: Distribution by Type of Product (Bioreactors and Fermenters), Fabrication Material (Glass, Stainless Steel and Single-use), Type of Bioprocess (Batch, Fed-batch and Continuous), Type of Biologic (Antibodies, Vaccines, Cell Therapies and Other Biologics), and Key Geographical Regions (North America, Europe, Asia-Pacific, Middle East and North Africa, and Latin America): Industry Trends and Global Forecasts, 2023-2035 report features an extensive study of the current market landscape and the likely future potential of the global bioreactors and fermenters market, over the next 12 years. It highlights the efforts of various stakeholders engaged in this rapidly emerging segment of the bioprocess equipment industry. Key inclusions of the report are briefly discussed below.

Growing Demand for Bioreactors and Fermenters

Over the past 25 years, there has been a steady increase in the sales of biologics, growing at a rate of 12–14% annually. In order cater to this growing demand, over 1,500 commercial scale biomanufacturing and contract manufacturing organization (CMO) facilities, equipped with bioreactors and / or fermenters have been established, globally.  Further, during the COVID-19 pandemic, several companies enhanced their vaccine production capabilities (through capacity expansion / technology upgradation), resulting in a surge in the sales of bioreactors. Moreover, the transition in the industry from high-volume biologics towards innovative specialized biologics, particularly those focused on treating rare conditions, has created a requirement for flexible manufacturing systems.  Consequently, there is an increasing demand for a diverse range of bioreactor systems (in term of design and mechanism of action), which includes disposable (single-use), stirred-tank, mini / micro, air lift, rocker, perfusion, wave bed, bubble column, fixed-bed, fluidized bed, membrane, packed bed, fibrous bed and photobioreactors. All these developments represent an additional avenue for revenue generation in this growing market.

Role of Bioprocess Equipment Manufacturers

The design aspect of both bioreactors and fermenters, operational across different types of bioprocesses (batch, fed batch and continuous), is a complex engineering task, requiring extensive understanding of cell growth, metabolism, genetic manipulation, and product expression. As a result, industry and non-industry players producing biomolecules / cellular therapies, are relying on original equipment manufacturers (OEMs) that produce different components of bioreactors, and / or engineering, procurement, and construction (EPCs) companies that integrate all the equipment designed by OEM engineers into a complete performing system. Manufacturers that are able to offer their clients modern equipment and infrastructure upgrades, effective life cycle management for their products, responsive customer service, expert troubleshooting of equipment issues, and annual maintenance contract to ensure efficient functioning of installed bioreactors without disruption, are the preferred partners. 

Current Market Landscape of Bioreactors and Fermenters

The global bioreactors and fermenters market landscape features more than 255 companies, which claim to possess the necessary technical expertise for manufacturing high-quality bioreactors and fermenters, in order to serve the biotechnology and biopharmaceutical industry. The market is currently dominated by small companies (1-50 employees), which represent 56% of the total number of players. Based on the requirement, bioreactors are produced using different fabrication materials, such as stainless steel, glass, and plastic, and are available in varying dimensions and volumes, ranging from micro-mini (less than 1 mL and 1 to 10 mL) to large-scale (more than 10,000 L). It is interesting to highlight that companies manufacturing miniature and small-scale bioreactors represent nearly 30% of the total players in this market. These bioreactor models are essential for conducting high-throughput experimental studies related to media development, strain improvement or process optimization. Further, recent developments in this domain indicate that majority of the bioreactor manufacturers have switched to advanced bioprocessing technology by integrating the automatic mode of operation.

Key Challenges in the Bioreactors and Fermenters Market 

Although disposable (single-use) bioreactors and fermenters have gained popularity due to their advantages, such as lower water and energy consumption (by approximately 45%), reduced initial investment costs (by 40%), and faster processing times for biologics (by 33%), they pose a risk of leachables and extractables (L&E). These  bioreactors are constructed using plastic materials that can release organic or inorganic chemicals into liquid pharmaceutical products, potentially jeopardizing the safety of the drug and the well-being of the patient.  The need for frequent purchases, variable costs per run, recurrent plastic disposal, and restricted capacity are some other potential bottlenecks restricting the widespread use of disposable (single-use) bioreactors.  While bioreactor manufacturers are striving to tackle these challenges through innovation in design and manufacturing methods, the increasing costs of procuring raw materials and ensuring that they align with the customers' budget, still remain a pressing concern.

Market Size of the Global Bioreactors and Fermenters Market

Driven by the rising demand for novel biopharmaceuticals, high adoption rates of precision medicine and regenerative medicine, along with advancement in bioprocessing technologies, the bioreactors and fermenters market is anticipated to witness a noteworthy growth in the foreseen future. Specifically, in terms of types of biologics, the market is anticipated to be driven by the high demand for manufacturing different antibody formats, including monoclonal and bispecific antibodies. Currently, majority of the revenues are generated from the sales of bioreactors that operate in batch and fed-batch modes; however, in the near future, market for bioreactors that operate in continuous mode is anticipated to grow at a relatively higher rate.  

Key Emerging Trends in Bioreactors and Fermenters Market

The bioreactors and fermenters market is witnessing the adoption of bioprocessing 4.0 solutions that leverage machine learning (ML) and artificial intelligence (AI) for real-time process monitoring. For instance, a US based company, Culture Biosciences, has designed an integrated bioreactor platform to design, monitor and analyze experiments, remotely via the cloud. The industry is also embracing advanced modular bioreactors that can be configured sequentially or in parallel. Further, the integration of controllers and automated systems is another technological advancement, that not only ensures that the processes continue to run within precise limits but also make the necessary adjustments, while minimizing the risk of human errors. 

Key Players Engaged in Manufacturing Bioreactors and Fermenters

The key players engaged in this domain (which have also been captured in this report) include Applikon Biotechnology, Bionet, Cytiva, Eppendorf, Merck, Ollital Technology, Parr Instrument Company, Sartorius, Shanghai Bailun Biological Technology, Solaris Biotech, Solida Biotech and Zhengzhou Laboao Instrument Equipment (LABAO).

Scope of the Report

The study presents an in-depth analysis of the various firms / organizations that are engaged in this domain, across different segments as defined in the below table:

Key Report Attributes Details

Forecast Period

  • 2023 – 2035

Type of Product

  • Bioreactors
  • Fermenters

Fabrication Material

  • Glass
  • Stainless Steel
  • Single-use

Type of Bioprocess

  • Batch and Fed-batch
  • Continuous

Type of Biologic

  • Antibodies
  • Vaccines
  • Cell Therapies
  • Other Biologics

Key Geographical Regions

  • North America
  • Europe
  • Asia-Pacific
  • Middle East and North Africa
  • Latin America

Key Companies Profiled

  • Applikon Biotechnology
  • Bionet
  • Cytiva
  • Eppendorf
  • Merck
  • Ollital Technology
  • Parr Instrument Company
  • Sartorius
  • Shanghai Bailun Biological Technology
  • Solaris Biotech
  • Solida Biotech
  • Zhengzhou Laboao Instrument Equipment (LABAO)
(Full list of 255+ companies captured in the market landscape analysis of the report)

Customization Scope

  • 15% Free Customization Option (equivalent to 5 analysts working days)

PowerPoint Presentation (Complimentary)

  • Available

Excel Data Packs (Complimentary)

  • Market Landscape Analysis
  • Company Competitiveness Analysis
  • Capacity Analysis
  • Market Forecast and Opportunity Analysis

The report presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain, across different regions. Amongst other elements, the report includes:

  • An executive summary of the insights captured during our research, offering a high-level view on the current state of the global bioreactors and fermenters market and its likely evolution in the mid-long term.
  • A general introduction to bioreactors and fermenters, along with details related to the components of a bioreactor. Additionally, the chapter presents information on different types of bioreactors based on type of bioprocess and mode of action. Further, it concludes with a discussion on applications of bioreactors and future perspectives in this domain. 
  • A detailed assessment of the overall market landscape of companies manufacturing bioreactors and fermenters, based on several relevant parameters, such as year of establishment, company size (in terms of number of employees), region of headquarters, geographical reach (North America, Europe, Asia-Pacific and Rest of the World), type of product (bioreactors and fermenters), capacity (micro-mini, small-scale, bench-scale, lab-scale, pilot-scale and large-scale), scale of operation (preclinical, clinical and commercial), scalability, type of bioprocess (batch, fed-batch and continuous), type of cell culture (2D cell culture, 3D cell culture and 4D cell culture), mode of operation (manual, semi-automatic and automatic) and type of end user (academic institutes and research laboratories, biopharmaceutical and pharmaceutical industries, contract manufacturing organizations, and contract research organizations).
  • A detailed competitiveness analysis of bioreactor and fermenter manufacturers based on manufacturer strength (in terms of years of experience and company size), portfolio strength (considering geographical reach, type of product, number of products in portfolio, type of bioreactor or fermenter, capacity, scale of operation, scalability, type of bioprocess, type of cell culture, mode of operation and end users).
  • Elaborate profiles of key players manufacturing bioreactors and fermenters (shortlisted on the basis of cumulative strength of manufacturers and product portfolio); each profile includes a brief overview of the company, along with information on its financial information (if available), product portfolio, recent developments and an informed future outlook. 
  • An estimate of the global installed bioreactors and fermenters capacity of biologics, based on information provided by various industry stakeholders in the public domain. It also features distribution of the available capacity on the basis of fabrication material (glass, stainless steel and single-use), source of cell culture (mammalian, microbial and others), reactor volume (less than 2,000 L, 2,000 to 5,000 L, 5,001 to 10,000 L and more than 10,000 L), type of manufacturer (in-house, hybrid and CMOs) and key geographical regions (North America, Europe, and Asia-Pacific and Rest of the World).
  • A case study on the market landscape of bioprocess controllers and automation systems, providing information on scale of operation (laboratory, clinical, and commercial), key features (scalability / ease to use, visual data display, remote accessibility, built-in system control sensors, expansive I/O compatibility and provisions for alarms / alerts), compatibility with bioreactor system (stirred tank (glass), single-use bioreactor, stirred tank (steel), fermenter, rocking motion), type of bioprocess (batch, fed-batch and perfusion), and type of process controlled (cell cultivation and microbial fermentation). In addition, the chapter presents details of companies involved in the development of bioprocess control software, upstream and downstream controllers, including information on their year of establishment, company size, and location of headquarters.

One of the key objectives of the report was to estimate the current opportunity and the future growth potential of the global bioreactors and fermenters market over the coming years. We have provided an informed estimate on the likely evolution of the market for the period, 2023-2035. Our year-wise projections of the current and forecasted opportunity have been further segmented based on relevant parameters, such as type of product (bioreactors and fermenters), fabrication material (glass, stainless steel and single-use), type of bioprocess (batch, fed-batch and continuous), type of biologic (antibodies, vaccines, cell therapies and other biologics), and key geographical regions (North America, Europe, Asia-Pacific, Middle East and North Africa, and Latin America). In order to account for future uncertainties associated with some of the key parameters and to add robustness to our model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic scenarios of the industry’s evolution.

The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders in this domain. The report features detailed transcripts of interviews held with the following individuals:

  • Sachin Kishor Chauhan (Director and Business Unit Head, Power and Energy, Oil and Gas, and Renewable Energy, Ensofa Projects)
  • N. V. Chaudhari (Founder and Director, Sunrise Process Equipments)
  • Per Stobbe (Chief Executive Officer, Marketing, Technical Support, CerCell)
  • Torsten Due Bryld (Chief Commercial Officer, CelVivo)

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

Frequently Asked Questions

Question 1: What is the global market size of bioreactors and fermenters?
Answer: The current global bioreactors and fermenters market size is anticipated to be over USD 25 billion. 

Question 2: Which are the top players in the global bioreactors and fermenters market?
Answer: Presently, more than 255 companies are engaged in manufacturing bioreactors and fermenters, worldwide. The top players engaged in this domain (which have also been captured in this report) include Applikon Biotechnology, Bionet, Cytiva, Eppendorf, Merck, Ollital Technology, Parr Instrument Company, Sartorius, Shanghai Bailun Biological Technology, Solaris Biotech, Solida Biotech and Zhengzhou Laboao Instrument Equipment (LABAO).

Question 3: What are the factors driving the global bioreactors and fermenters market?
Answer: The factors driving the global bioreactors and fermenters market include advancement in bioprocessing technologies, and the surge in demand for novel biopharmaceuticals, such as precision and regenerative medicine.

Question 4: Which region has the highest market share in global bioreactors and fermenters market?
Answer: North America and Europe capture around 60% share in the current global bioreactors and fermenters market, followed by Asia-Pacific. It is worth mentioning that, within Asia-Pacific, majority of the market share is contributed by China and India.

Question 5: What are the leading market segments in global bioreactors and fermenters market?
Answer: Currently, in terms of fabrication material, stainless steel bioreactors / fermenters capture the largest share of this market. However, single-use bioreactors / fermenters are likely to witness higher annual growth rates in the upcoming years, owing to their smaller footprint, cost efficiency and increased productivity. Further, in terms of type of biologic, cell culture systems used for the production of antibodies are anticipated to capture a prominent share of the current and future market.

Question 6: Which segment, in terms of bioreactor / fermenter capacity, accounts for the largest share in the global bioreactors and fermenters market?
Answer: The capacity of the bioreactors varies, ranging from a few milliliters to several liters, contingent upon the specific design and operational mode employed across diverse bioprocesses.  At present, the global bioreactors and fermenters market is dominated by laboratory-scale bioreactors / fermenters. This category considers bioreactors / fermenters in the volume range of 1 L to 299 L. This is followed by pilot-scale bioreactors (300 L to 10,000 L) and bench-scale bioreactors (101 mL to 999 mL).

Question 7: What is the growth rate (CAGR) in the global bioreactors and fermenters market?
Answer: The global bioreactors and fermenters market size is projected to grow at a CAGR of ~12% in the coming years.

Question 8: What are the upcoming trends in the global bioreactors and fermenters market?
Answer: The industry is presently witnessing the rising adoption of bioprocessing 4.0 solutions leveraging AI and ML for real-time process monitoring. Further, in order to ensure that the bioprocess runs within the precise limits, several players have integrated automated bioprocess controllers that offer various additional benefits, such as lowering of production and labor cost (by 20-30%), optimizing the energy consumption (by 5-30%) and increasing the overall productivity (by 10-20%).

Contents

Table Of Contents

1. PREFACE
1.1. Introduction
1.2. Key Market Insights
1.3.  Scope of the Report
1.4.  Research Methodology
1.5.  Frequently Asked Questions
1.6. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION
3.1. Chapter Overview
3.2. Overview of Bioreactors
3.3. Components of a Bioreactor 
3.4. Types of Bioreactors
3.4.1. Classification based on Type of Bioprocess
3.4.2. Classification based on Mode of Action
3.5. Applications of Bioreactors
3.6. Future Perspectives

4. BIOREACTOR AND FERMENTER MANUFACTURERS: MARKET LANDSCAPE
4.1.  Chapter Overview
4.2.  Bioreactor and Fermenter Manufacturers: Overall Market Landscape
4.2.1.  Analysis by Year of Establishment
4.2.2.  Analysis by Company Size
4.2.3.  Analysis by Region of Headquarters
4.2.4.  Analysis by Location of Headquarters
4.2.5.  Analysis by Year of Establishment and Region of Headquarters
4.2.6.  Analysis by Company Size and Region of Headquarters
4.2.7.  Analysis by Year of Establishment, Company Size and Region of Headquarters
4.2.8. Analysis by Geographical Reach
4.2.9.  Analysis by Region of Headquarters and Geographical Reach
4.2.10. Analysis by Type of Product 
4.2.11. Analysis by Capacity
4.2.12.  Analysis by Scale of Operation
4.2.13.  Analysis by Scalability
4.2.14.  Analysis by Type of Bioprocess
4.2.15. Analysis by Type of Cell Culture
4.2.16. Analysis by Mode of Operation
4.2.17. Analysis by Type of End-user

5. COMPANY COMPETITIVENESS ANALYSIS
5.1. Chapter Overview
5.2. Assumptions / Key Parameters
5.3. Methodology
5.4. Company Competitiveness Analysis: Small Companies
5.4.1. Company Competitiveness Analysis: Small Companies based in North America
5.4.2. Company Competitiveness Analysis: Small Companies based in Europe
5.4.3. Company Competitiveness Analysis: Small Companies based in Asia-Pacific and Rest of the World

5.5. Company Competitiveness Analysis: Mid-sized Companies
5.5.1. Company Competitiveness Analysis: Mid-sized Companies based in North America
5.5.2. Company Competitiveness Analysis: Mid-sized Companies based in Europe
5.5.3. Company Competitiveness Analysis: Mid-sized Companies based in Asia-Pacific and Rest of the World

5.6. Company Competitiveness Analysis: Large and Very Large Companies

6. COMPANY PROFILES
6.1. Chapter Overview
6.2. Applikon Biotechnology (acquired by Getinge)
6.2.1. Company Overview
6.2.2. Product Portfolio
6.2.3. Recent Developments and Future Outlook

6.3. Bionet
6.3.1. Company Overview
6.3.2. Product Portfolio
6.3.3. Recent Developments and Future Outlook

6.4. Cytiva
6.4.1. Company Overview
6.4.2. Financial Information
6.4.3. Product Portfolio
6.4.4. Recent Developments and Future Outlook

6.5. Eppendorf
6.5.1. Company Overview
6.5.2. Financial Information
6.5.3. Product Portfolio
6.5.4. Recent Developments and Future Outlook

6.6. Merck
6.6.1. Company Overview
6.6.2. Financial Information
6.6.3. Product Portfolio
6.6.4. Recent Developments and Future Outlook

6.7. Ollital Technology
6.7.1. Company Overview
6.7.2. Product Portfolio
6.7.3. Recent Developments and Future Outlook

6.8. Parr Instrument Company
6.8.1. Company Overview
6.8.2. Product Portfolio
6.8.3. Recent Developments and Future Outlook

6.9. Sartorius
6.9.1. Company Overview
6.9.2. Financial Information
6.9.3. Product Portfolio
6.9.4. Recent Developments and Future Outlook

6.10. Shanghai Bailun Biological Technology
6.10.1. Company Overview
6.10.2. Product Portfolio
6.10.3. Recent Developments and Future Outlook

6.11. Solaris Biotech (acquired by Donaldson Company)
6.11.1. Company Overview
6.11.2. Product Portfolio
6.11.3. Recent Developments and Future Outlook

6.12. Solida Biotech
6.12.1. Company Overview
6.12.2. Product Portfolio
6.12.3. Recent Developments and Future Outlook

6.13. Zhengzhou Laboao Instrument Equipment (LABAO)
6.13.1. Company Overview
6.13.2. Product Portfolio
6.13.3. Recent Developments and Future Outlook

7. CAPACITY ANALYSIS
7.1.  Chapter Overview
7.2.  Key Assumptions and Methodology
7.2.1 Bioreactors and Fermenters: Global Installed Capacity of Biologics
7.2.1.1. Analysis by Fabrication Material
7.2.1.2. Analysis by Source of Cell Culture
7.2.1.3. Analysis by Reactor Volume
7.2.1.4. Analysis by Type of Manufacturer
7.2.1.5. Analysis by Key Geographical Regions

7.3. Concluding Remarks

8. CASE STUDY: BIOPROCESS CONTROLLERS AND AUTOMATION SYSTEMS
8.1. Chapter Overview
8.2.  Bioprocess Control Software: Overall Market Landscape
8.2.1.  Analysis by Scale of Operation
8.2.2.  Analysis by Key Features
8.2.3.  Analysis by Compatibility with System
8.2.4.  Analysis by Type of Process Controlled

8.3.  Bioprocess Control Software Developers: Overall Market Landscape
8.3.1.  Analysis by Year of Establishment
8.3.2.  Analysis by Company Size
8.3.3.  Analysis by Location of Headquarters

8.4.  Upstream Controllers: Overall Market Landscape
8.4.1.  Analysis by Scale of Operation
8.4.2.  Analysis by Key Features
8.4.3.  Analysis by Compatibility with Bioreactor System
8.4.4.  Analysis by Type of Bioprocess
8.4.5.  Analysis by Type of Process Controlled

8.5.  Upstream Controller Developers: Overall Market Landscape
8.5.1.  Analysis by Year of Establishment
8.5.2.  Analysis by Company Size
8.5.3.  Analysis by Location of Headquarters

8.6.  Downstream Controller Systems: Overall Market Landscape
8.6.1.  Analysis by Scale of Operation
8.6.2.  Analysis by Key Features
8.6.3.  Analysis by Type of System
8.6.4.  Analysis by Type of Bioprocess
8.6.5.  Analysis by Application Area

8.7.  Downstream Controller System Developers: Overall Market Landscape
8.7.1.  Analysis by Year of Establishment
8.7.2.  Analysis by Company Size
8.7.3.  Analysis by Location of Headquarters 

9. MARKET FORECAST
9.1. Chapter Overview
9.2. Key Assumptions and Forecast Methodology

9.3. Global Bioreactors and Fermenters Market, 2023-2035
9.3.1. Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Product
9.3.1.1. Global Bioreactors Market, 2023-2035
9.3.1.2. Global Fermenters Market, 2023-2035

9.3.2. Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Fabrication Material
9.3.2.1. Global Glass Bioreactors and Fermenters Market, 2023-2035
9.3.2.2. Global Stainless Steel Bioreactors and Fermenters Market, 2023-2035
9.3.2.3. Global Single-use Bioreactors and Fermenters Market, 2023-2035

9.3.3. Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Bioprocess
9.3.3.1. Global Bioreactors and Fermenters Market for Batch and Fed-batch Process, 2023-2035
9.3.3.2. Global Bioreactors and Fermenters Market for Continuous Process, 2023-2035

9.3.4. Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Biologic
9.3.4.1. Global Bioreactors and Fermenters Market for Antibodies, 2023-2035
9.3.4.2. Global Bioreactors and Fermenters Market for Vaccines, 2023-2035
9.3.4.3. Global Bioreactors and Fermenters Market for Cell Therapies, 2023-2035
9.3.4.4. Global Bioreactors and Fermenters Market for Other Biologics, 2023-2035

9.3.5. Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Key Geographical Regions
9.3.5.1.  Global Bioreactors and Fermenters Market in North America, 2023-2035
9.3.5.2.  Global Bioreactors and Fermenters Market in Europe, 2023-2035
9.3.5.3.  Global Bioreactors and Fermenters Market in Asia-Pacific, 2023-2035
9.3.5.4.  Global Bioreactors and Fermenters Market in Middle East and North Africa, 2023-2035
9.3.5.5.  Global Bioreactors and Fermenters Market in Latin America, 2023-2035

10. EXECUTIVE INSIGHTS 

11. CONCLUDING REMARKS

12. APPENDIX 1: TABULATED DATA

13. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List Of Figures

Figure 2.1 Executive Summary: Overall Market Landscape
Figure 2.2 Executive Summary: Capacity Analysis
Figure 2.3 Executive Summary: Market Forecast
Figure 3.1 Components of a Bioreactor
Figure 3.2 Types of Bioreactors (based on Type of Bioprocess)
Figure 3.3 Types of Bioreactors (based on Mode of Action)
Figure 3.4 Industries Employing Bioreactors 
Figure 3.5 Applications of Bioreactors in Pharmaceutical Industry
Figure 4.1 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment
Figure 4.2 Bioreactor and Fermenter Manufacturers: Distribution by Company Size
Figure 4.3 Bioreactor and Fermenter Manufacturers: Distribution by Region of Headquarters
Figure 4.4 Bioreactor and Fermenter Manufacturers: Distribution by Location of Headquarters
Figure 4.5 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment and Region of Headquarters
Figure 4.6 Bioreactor and Fermenter Manufacturers: Distribution by Company Size and Region of Headquarters
Figure 4.7 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment, Company Size and Region of Headquarters
Figure 4.8 Bioreactor and Fermenter Manufacturers: Distribution by Geographical Reach
Figure 4.9 Bioreactor and Fermenter Manufacturers: Distribution by Region of Headquarters and Geographical Reach
Figure 4.10 Bioreactor and Fermenter Manufacturers: Distribution by Type of Product
Figure 4.11 Bioreactor and Fermenter Manufacturers: Distribution by Capacity
Figure 4.12 Bioreactor and Fermenter Manufacturers: Distribution by Scale of Operation
Figure 4.13 Bioreactor and Fermenter Manufacturers: Distribution by Scalability
Figure 4.14 Bioreactor and Fermenter Manufacturers: Distribution by Type of Bioprocess
Figure 4.15 Bioreactor and Fermenter Manufacturers: Distribution by Type of Cell Culture
Figure 4.16 Bioreactor and Fermenter Manufacturers: Distribution by Mode of Operation
Figure 4.17 Bioreactor and Fermenter Manufacturers: Distribution by Type of End-user
Figure 5.1 Competitiveness Analysis: Small Companies 
Figure 5.2 Competitiveness Analysis: Small Companies based in North America 
Figure 5.3 Competitiveness Analysis: Small Companies based in Europe
Figure 5.4 Competitiveness Analysis: Small Companies based in Asia-Pacific and Rest of the World
Figure 5.5 Competitiveness Analysis: Mid-sized Companies 
Figure 5.6 Competitiveness Analysis: Mid-sized Companies based in North America 
Figure 5.7 Competitiveness Analysis: Mid-sized Companies based in Europe
Figure 5.8 Competitiveness Analysis: Mid-sized Companies based in Asia-Pacific and Rest of the World
Figure 5.9 Competitiveness Analysis: Large and Very Large Companies 
Figure 5.10 Competitiveness Analysis of Bioreactor and Fermenter Manufacturers: Competitiveness Score of Top Players
Figure 6.1 Cytiva: Annual Revenues, FY 2017-FY 2021 (USD Million)
Figure 6.2 Eppendorf: Annual Revenues, FY 2017-FY 2021 (EUR Million)
Figure 6.3 Merck: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Figure 6.4 Sartorius: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Figure 7.1 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Fabrication Material
Figure 7.2 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Source of Cell Culture
Figure 7.3 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Reactor Volume
Figure 7.4 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Type of Manufacturer
Figure 7.5 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Key Geographical Regions
Figure 8.1 Bioprocess Control Software: Distribution by Scale of Operation
Figure 8.2 Bioprocess Control Software: Distribution by Key Features
Figure 8.3 Bioprocess Control Software: Distribution by Compatibility with System
Figure 8.4 Bioprocess Control Software: Distribution by Type of Process Controlled
Figure 8.5 Bioprocess Control Software Developers: Distribution by Year of Establishment
Figure 8.6 Bioprocess Control Software Developers: Distribution by Company Size
Figure 8.7 Bioprocess Control Software Developers: Distribution by Location of Headquarters
Figure 8.8 Upstream Controllers: Distribution by Scale of Operation
Figure 8.9 Upstream Controllers: Distribution by Key Features
Figure 8.10 Upstream Controllers: Distribution by Compatibility with Bioreactor System
Figure 8.11 Upstream Controllers: Distribution by Type of Bioprocess
Figure 8.12 Upstream Controllers: Distribution by Type of Process Controlled
Figure 8.13 Upstream Controller Developers: Distribution by Year of Establishment
Figure 8.14 Upstream Controller Developers: Distribution by Company Size
Figure 8.15 Upstream Controller Developers: Distribution by Location of Headquarters
Figure 8.16 Downstream Controller Systems: Distribution by Scale of Operation
Figure 8.17 Downstream Controller Systems: Distribution by Key Features
Figure 8.18 Downstream Controller Systems: Distribution by Type of System
Figure 8.19 Downstream Controller Systems: Distribution by Type of Bioprocess
Figure 8.20 Downstream Controller Systems: Distribution by Application Area
Figure 8.21 Downstream Controller System Developers: Distribution by Year of Establishment
Figure 8.22 Downstream Controller System Developers: Distribution by Company Size
Figure 8.23 Downstream Controller System Developers: Distribution by Location of Headquarters 
Figure 9.1 Global Bioreactors and Fermenters Market, 2023-2035 (USD Billion)
Figure 9.2 Global Bioreactors and Fermenters Market, 2023 and 2035: Distribution by Type of Product (USD Billion)
Figure 9.3 Global Bioreactors Market, 2023- 2035 (USD Billion)
Figure 9.4 Global Fermenters Market, 2023- 2035 (USD Billion)
Figure 9.5 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Fabrication Material
Figure 9.6 Global Glass Bioreactors and Fermenters Market, 2023-2035
Figure 9.7 Global Stainless Steel Bioreactors and Fermenters Market, 2023-2035
Figure 9.7 Global Single-use Bioreactors and Fermenters Market, 2023-2035
Figure 9.8 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Bioprocess
Figure 9.9 Global Bioreactors and Fermenters Market for Batch and Fed-batch Process, 2023-2035
Figure 9.10 Global Bioreactors and Fermenters Market for Continuous Process, 2023-2035
Figure 9.11 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Biologic
Figure 9.12 Global Bioreactors and Fermenters Market for Antibodies, 2023-2035
Figure 9.13 Global Bioreactors and Fermenters Market for Vaccines, 2023-2035
Figure 9.14 Global Bioreactors and Fermenters Market for Cell Therapies, 2023-2035
Figure 9.15 Global Bioreactors and Fermenters Market for Other Biologics, 2023-2035
Figure 9.16 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Key Geographical Regions
Figure 9.17 Bioreactors and Fermenters Market in North America, 2023-2035
Figure 9.18 Bioreactors and Fermenters Market in Europe, 2023-2035
Figure 9.19 Bioreactors and Fermenters Market in Asia-Pacific, 2023-2035
Figure 9.20 Bioreactors and Fermenters Market in Middle East and North Africa, 2023-2035
Figure 9.21 Bioreactors and Fermenters Market in Latin America, 2023-2035
Figure 11.1 Concluding Remarks: Overall Market Landscape of Bioreactor and Fermenter Manufacturers
Figure 11.2 Concluding Remarks: Geographical Distribution of Bioreactor and Fermenter Manufacturers
Figure 11.3 Concluding Remarks: Capacity Analysis
Figure 11.4 Concluding Remarks: Market Forecast

List Of Tables

Table 4.1 Bioreactor and Fermenter Manufacturers: List of Companies
Table 4.2 Bioreactor and Fermenter Manufacturers: Information on Geographical Reach
Table 4.3 Bioreactor and Fermenter Manufacturers: Information on Volume and Type of Bioreactor and Fermenter
Table 4.4 Bioreactor and Fermenter Manufacturers: Information on Scale of Operation and Scalability 
Table 4.5 Bioreactor and Fermenter Manufacturers: Type of Bioprocess and Type of Cell Culture
Table 4.6 Bioreactor and Fermenter Manufacturers: Information on Mode of Operation and Type of End-user
Table 6.1 Bioreactor and Fermenter Manufacturers: List of Profiled Companies
Table 6.2 Applikon Biotechnology: Company Snapshot
Table 6.3 Applikon Biotechnology: Bioreactor Portfolio
Table 6.4 Applikon Biotechnology: Recent Developments and Future Outlook
Table 6.5 Bionet: Company Snapshot
Table 6.6 Bionet: Bioreactor Portfolio
Table 6.7 Bionet: Recent Developments and Future Outlook
Table 6.8 Cytiva: Company Snapshot
Table 6.9 Cytiva: Bioreactor Portfolio
Table 6.10 Cytiva: Recent Developments and Future Outlook
Table 6.11 Eppendorf: Company Snapshot
Table 6.12 Eppendorf: Bioreactor Portfolio
Table 6.13 Eppendorf: Recent Developments and Future Outlook
Table 6.14 Merck: Company Snapshot
Table 6.15 Merck: Bioreactor Portfolio
Table 6.16 Merck: Recent Developments and Future Outlook
Table 6.17 Ollital Technology: Company Snapshot
Table 6.18 Ollital Technology: Bioreactor Portfolio
Table 6.19 Ollital Technology: Recent Developments and Future Outlook
Table 6.20 Parr Instrument Company: Company Snapshot
Table 6.21 Parr Instrument Company: Bioreactor Portfolio
Table 6.22 Parr Instrument Company: Recent Developments and Future Outlook
Table 6.23 Sartorius: Company Snapshot
Table 6.24 Sartorius: Bioreactor Portfolio
Table 6.25 Sartorius: Recent Developments and Future Outlook
Table 6.26 Shanghai Bailun Biological Technology: Company Snapshot
Table 6.27 Shanghai Bailun Biological Technology: Bioreactor Portfolio
Table 6.28 Shanghai Bailun Biological Technology: Recent Developments and Future Outlook
Table 6.29 Solaris Biotech: Company Snapshot
Table 6.30 Solaris Biotech: Bioreactor Portfolio
Table 6.31 Solaris Biotech: Recent Developments and Future Outlook
Table 6.32 Solida Biotech: Company Snapshot
Table 6.33 Solida Biotech: Bioreactor Portfolio
Table 6.34 Solida Biotech: Recent Developments and Future Outlook
Table 6.35 Zhengzhou Laboao Instrument Equipment (LABAO): Company Snapshot
Table 6.36 Zhengzhou Laboao Instrument Equipment (LABAO): Bioreactor Portfolio
Table 6.37 Zhengzhou Laboao Instrument Equipment (LABAO): Recent Developments and Future Outlook
Table 7.1 Capacity Analysis: Information on Contract Biomanufacturing Capacity
Table 7.2 Capacity Analysis: Average Capacity per Category (Sample Data Set)
Table 7.3 Capacity Analysis: Average Capacity for Mammalian Expression System (Sample Data Set)
Table 7.4 Capacity Analysis: Average Capacity for Microbial Expression System (Sample Data Set)
Table 7.5 Capacity Analysis: Global Distribution of Contract, in-house and Hybrid Biomanufacturing Capacity
Table 8.1 Bioprocess Control Software: Information on Key Features, Compatibility with Bioreactor System and Process Controlled 
Table 8.2 Upstream Controllers: Information on Key Features, Type of Bioprocess and Compatibility with Bioreactor System
Table 8.3 Downstream Controller Systems: Information on Key Features, Type of System, Type of Bioprocess and Application Area
Table 10.1 Ensofa Projects: Key Highlights
Table 10.2 Sunrise Process Equipments: Key Highlights
Table 10.3 CerCell: Key Highlights
Table 10.4 CelVivo: Key Highlights
Table 12.1 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment
Table 12.2 Bioreactor and Fermenter Manufacturers: Distribution by Company Size
Table 12.3 Bioreactor and Fermenter Manufacturers: Distribution by Region of Headquarters
Table 12.4 Bioreactor and Fermenter Manufacturers: Distribution by Location of Headquarters
Table 12.5 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment and Region of Headquarters
Table 12.6 Bioreactor and Fermenter Manufacturers: Distribution by Company Size and Region of Headquarters
Table 12.7 Bioreactor and Fermenter Manufacturers: Distribution by Year of Establishment, Company Size and Region of Headquarters
Table 12.8 Bioreactor and Fermenter Manufacturers: Distribution by Geographical Reach
Table 12.9 Bioreactor and Fermenter Manufacturers: Distribution by Region of Headquarters Region and Geographical Reach
Table 12.10 Bioreactor and Fermenter Manufacturers: Distribution by Type of Product
Table 12.11 Bioreactor and Fermenter Manufacturers: Distribution by Capacity
Table 12.12 Bioreactor and Fermenter Manufacturers: Distribution by Scale of Operation
Table 12.13 Bioreactor and Fermenter Manufacturers: Distribution by Scalability
Table 12.14 Bioreactor and Fermenter Manufacturers: Distribution by Type of Bioprocess
Table 12.15 Bioreactor and Fermenter Manufacturers: Analysis by Type of Cell Culture
Table 12.16 Bioreactor and Fermenter Manufacturers: Analysis by Mode of Operation
Table 12.17 Bioreactor and Fermenter Manufacturers: Analysis by Type of End-user
Table 12.18 Cytiva: Annual Revenues, FY 2017-FY 2021 (USD Million)
Table 12.19 Eppendorf: Annual Revenues, FY 2017-FY 2021 (EUR Million)
Table 12.20 Merck: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Table 12.21 Sartorius: Annual Revenues, FY 2017-FY 2022 (EUR Billion)
Table 12.22 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Fabrication Material
Table 12.23 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Source of Cell Culture
Table 12.24 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Reactor Volume
Table 12.25 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Type of Manufacturer
Table 12.26 Global Installed Bioreactors and Fermenters Capacity (by Million Liters): Distribution by Key Geographical Regions
Table 12.27 Bioprocess Control Software: Distribution by Scale of Operation
Table 12.28 Bioprocess Control Software: Distribution by Key Features
Table 12.29 Bioprocess Control Software: Distribution by Compatibility with Systems
Table 12.30 Bioprocess Control Software: Distribution by Type of Process Controlled
Table 12.31 Bioprocess Control Software Developers: Distribution by Year of Establishment
Table 12.32 Bioprocess Control Software Developers: Distribution by Company Size
Table 12.33 Bioprocess Control Software Developers: Distribution by Location of Headquarters
Table 12.34 Upstream Controllers: Distribution by Scale of Operation
Table 12.35 Upstream Controllers: Distribution by Key Features
Table 12.36 Upstream Controllers: Distribution by Compatibility with Bioreactor Systems
Table 12.37 Upstream Controllers: Distribution by Type of Bioprocess
Table 12.38 Upstream Controllers: Distribution by Type of Process Controlled
Table 12.39 Upstream Controller Developers: Distribution by Year of Establishment
Table 12.40 Upstream Controller Developers: Distribution by Company Size
Table 12.41 Upstream Controller Developers: Distribution by Location of Headquarters
Table 12.42 Downstream Controller Systems: Distribution by Scale of Operation
Table 12.43 Downstream Controller Systems: Distribution by Key Features
Table 12.44 Downstream Controller Systems: Distribution by Type of System
Table 12.45 Downstream Controller Systems: Distribution by Type of Bioprocess
Table 12.46 Downstream Controller Systems: Distribution by Application Area
Table 12.47 Downstream Controller System Developers: Distribution by Year of Establishment
Table 12.48 Downstream Controller System Developers: Distribution by Company Size
Table 12.49 Downstream Controller System Developers: Distribution by Location of Headquarters 
Table 12.50 Global Bioreactors and Fermenters Market, 2023-2035 (USD Billion)
Table 12.51 Global Bioreactors and Fermenters Market, 2023 and 2035: Distribution by Type of Product (USD Billion)
Table 12.52 Global Bioreactors Market, 2023- 2035 (USD Billion)
Table 12.53 Global Fermenters Market, 2023- 2035 (USD Billion)
Table 12.54 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Fabrication Material
Table 12.55 Global Glass Bioreactors and Fermenters Market, 2023-2035
Table 12.56 Global Stainless-Steel Bioreactors and Fermenters Market, 2023-2035
Table 12.57 Global Single-use Bioreactors and Fermenters Market, 2023-2035
Table 12.58 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Bioprocess
Table 12.59 Global Bioreactors and Fermenters Market for Batch and Fed-batch Process, 2023-2035
Table 12.60 Global Bioreactors and Fermenters Market for Continuous Process, 2023-2035
Table 12.61 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Type of Biologic
Table 12.62 Global Bioreactors and Fermenters Market for Antibodies, 2023-2035
Table 12.63 Global Bioreactors and Fermenters Market for Vaccines, 2023-2035
Table 12.64 Global Bioreactors and Fermenters Market for Cell Therapies, 2023-2035
Table 12.65 Global Bioreactors and Fermenters Market for Other Biologics, 2023-2035
Table 12.66 Global Bioreactors and Fermenters Market, 2023-2035: Distribution by Key Geographical Regions
Table 12.67 Bioreactors and Fermenters Market in North America, 2023-2035
Table 12.68 Bioreactors and Fermenters Market in Europe, 2023-2035
Table 12.69 Bioreactors and Fermenters Market in Asia-Pacific, 2023-2035
Table 12.70 Bioreactors and Fermenters Market in Middle East and North Africa, 2023-2035
Table 12.71 Bioreactors and Fermenters Market in Latin America, 2023-2035

List Of Companies

The following companies and organizations have been mentioned in the report:

  1. 2mag
  2. 3D Biotek
  3. 3Dnamics
  4. ABEC
  5. Ablaze Export
  6. Ablaze Glass Works
  7. ABLE  & biott 
  8. Ace Glass
  9. Advanced Process Systems (APS)
  10. Agilitech
  11. Aishengk
  12. Aizon
  13. AlgaBloom International
  14. Alol Instruments
  15. Amerging Technologies
  16. American Alloy Fabricators
  17. Amixon
  18. Amstrong Biotech 
  19. Analytical Technologies
  20. Andel Equipment
  21. Anton Paar
  22. Applikon Biotechnology (Acquired by Getinge)
  23. Aroko Bioengineering
  24. artelis
  25. ARTeSYN BioSolutions
  26. AUCTEQ Biosystems
  27. Augusta Fiberglass
  28. Automated Engineering Services (AES)
  29. Avantica Pharmaceuticals
  30. Telstar (Subsidiary of Azbil)
  31. B&P Engineering
  32. Shanghai Bailun Biological Technology
  33. bbi-biotech
  34. Beckman Coulter 
  35. Belach Bioteknik
  36. Bellco Glass
  37. Berghof Products + Instruments
  38. Bevo Tech
  39. Bharat Process Equipment
  40. Bilfinger Life Science
  41. BINDER
  42. Bio Techno Vision
  43. Bio-Age Equipment & Services
  44. BioBridge Healthcare Solutions
  45. Biochrome India
  46. Bioengineering 
  47. BioFluid Control Systems
  48. Biolinx Labsystems
  49. Biomade India
  50. Biomatrix Systems & Services
  51. BIONET
  52. BioPharm Engineered Systems
  53. Bioprocess Technology
  54. BioReactor Sciences
  55. Bioreactors.net
  56. Biosan
  57. Biostream 
  58. BIOTECHNO
  59. Biotechnologies 
  60. Biotree
  61. BiOZEEN
  62. BioZEN Labs
  63. BISS TGT
  64. BlueSens
  65. Borg Scientific
  66. Brihat Bio-Engineering
  67. Broadley-James
  68. Buchiglas
  69. Byron Bioreactor Technologies
  70. Carelab Technology
  71. Cassia Siamia Technologies
  72. Celartia
  73. Celeritus Engineering
  74. Cell Culture Company
  75. CELLEC Biotek 
  76. Cellexus
  77. Celltainer Biotech
  78. CelVivo
  79. Centrion
  80. CerCell 
  81. CESCO Bioengineering
  82. Chema Prozeß- und Systemtechnik
  83. Chemglass Life Sciences
  84. Chemiplant Engineering
  85. Chemtrix
  86. Cleaver Scientific
  87. Codex Research
  88. Corning
  89. Cultiply
  90. Culturing Solutions
  91. Cytiva
  92. D D Automation & Engineers
  93. DCI-Biolafitte
  94. De Dietrich Process Systems
  95. Designinnova (Subsidiary of Arrow Weighing System)
  96. DHRUV FABROTECH
  97. Distek
  98. Doga
  99. Dyna Biotech
  100. EASTBIO (Zhenjiang East Biotech Equipment and Technology)
  101. Eco Green Technologies
  102. edesign Valvtec
  103. Electrolab Biotech
  104. Endülüs Krom
  105. Ensofa Projects
  106. Eppendorf
  107. Erbi Biosystems (Acquired by Merck)
  108. Esco
  109. Fabitech
  110. Fermentec
  111. Fermenter Bioreactor India
  112. Fermetec Resources
  113. Fermex Solutions
  114. FiberCell Systems
  115. FIERUS Rohr- & Anlagenbau Druckbehälterbau
  116. Flexcell International
  117. Flotek
  118. Frings
  119. Fuzhou FUL Fluid Equipment & Pharmaceutical
  120. G&F Manufacturing Company
  121. G&G Technologies
  122. Gak Equipments and Technologies
  123. Galbino Technology
  124. GMM Pfaudler
  125. GOAVEC Engineering
  126. Gongyi Yuhua Instrument
  127. GPC Bio
  128. Jinzong Machinery
  129. H.E.L 
  130. Hamilton
  131. Harvard Apparatus (Subsidiary of Harvard Bioscience)
  132. Henan Lanphan Industry
  133. Hexamide Agro Tech
  134. High Purity New England
  135. HiTec Zang
  136. idoneus
  137. IKA
  138. ILS Automation
  139. Industrial Plankton
  140. INFORS HT
  141. Innova Bio-Meditech
  142. Inofinity Tech
  143. INOXPA
  144. International Filter Products
  145. ITB Biopharm
  146. KARADANI ENGINEERING
  147. KERONE Engineering Solutions
  148. KNIK Technology
  149. Krishna Scientific Suppliers
  150. Kuhner shaker
  151. KYNOTA (A subsidiary of NECI)
  152. Labfirst Scientific Instruments
  153. Labmate Scientific
  154. Labotronics
  155. Labtronixed
  156. LAMBDA Laboratory Instruments
  157. Lark innovative Fine Teknowledge
  158. LEBAS INDUSTRIES
  159. Lee Industries
  160. Lelesil Innovative Systems
  161. LePure Biotech
  162. Liaoyang Sinotech Technology Development
  163. Liquidyne 
  164. Made in Brunel
  165. Madhav Automation & STP Solutions
  166. Magic Technology
  167. Major Science
  168. Manidharma Biotech
  169. Maruti Engineering 
  170. Materia Nova
  171. MDX Biotechnik International
  172. Mecgene Instrument Technologies
  173. Membio 
  174. Merck 
  175. MicroDigital 
  176. Motors India
  177. MSM Process Solutions
  178. MURHOPYE SCIENTIFIC COMPANY
  179. Nanjing A & M Technology
  180. Nanjing Ningbo Instrument
  181. Nanjing Ningkai Instrument
  182. Nantong Sanjing Chemglass
  183. Napro Scientific
  184. NeoTech Water Solutions
  185. Nes India Engineers
  186. New Horizon Biotechnology
  187. Nordic Engineering
  188. Novaferm
  189. Ollital Technology
  190. Omni Life Science
  191. OmniBRx Biotechnologies
  192. Padmatech Industries
  193. Pall Corporation
  194. Paragon Bio-Engineering
  195. Parker Hannifin
  196. Parr Instrument Company
  197. Patel Agro Biotech
  198. Paul Mueller Company
  199. Pavika Equipments And Technologies
  200. PBS Biotech
  201. PendoTECH
  202. PerfuseCell
  203. Peschl Ultraviolet
  204. Pharmabios 
  205. Pharmacon 
  206. Phenometrics
  207. Pierre Guérin
  208. Praj HiPurity Systems
  209. Prime Care Technology
  210. ProlifeCell 
  211. PRS Bio & Automation Solutions
  212. Q Labtech
  213. Qi Yu Industry (Shanghai)
  214. Quantek Instruments
  215. Quark Glass (Acquired by Andrews Glass)
  216. Quinxell Technologies
  217. Real Ions Technologies
  218. RealBio Technology
  219. Refine Technology
  220. Regemat 3D
  221. Regenere 3D
  222. Repligen
  223. ReproCell
  224. Rigenerand (Acquired by Evotec)
  225. Roch Mechatronics
  226. Roggetec Mader
  227. Rotech Bioengineering
  228. Ruland 
  229. SS Engineers
  230. S2 Engineering Industries
  231. Sartorius
  232. SATAKE MultiMix
  233. Scigenics
  234. Scinus
  235. Sentinel Process Systems
  236. Sepragen
  237. Shakti Lab Equipment
  238. Shanghai Baoxing Bio-Engineering Equipment (BXBIO)
  239. Shanghai Iven Pharmatech Engineering
  240. Shanghai Ritai Medicine Equipment Project
  241. Shanghai Shenheng Biological Technology
  242. Shanghai Yuanhuai Industrial 
  243. Shanghai Yuhua Instrument Equipment
  244. Sharad Agencies
  245. Shree Bhagwati Machtech
  246. Shree Biocare
  247. SKE Research Equipment
  248. SM Biosystems
  249. Solaris Biotech 
  250. Solida Biotech
  251. SpectraA Technology Solutions
  252. Spectrochem Instruments
  253. SpinChem
  254. Steel-Pro
  255. StemCell Systems
  256. Subitec
  257. Sunrise Process Equipments
  258. Super Scientific Works
  259. Synthecon
  260. Syrris
  261. SYSBIOTECH
  262. System Technik Deutschland (SYSTAG)
  263. T&J Bioengineering
  264. TA Instruments (Subsidiary of Waters Corporation)
  265. Techniserv
  266. Techno Service
  267. TECNIC 
  268. Thermo Fisher Scientific
  269. Trace Bio Tech
  270. Trident Labortek
  271. TRL Instruments
  272. Truking Technology
  273. Univercells Technologies
  274. V R Process Engineering Consultants
  275. VERDOT Ips²
  276. Vinay Enterprises
  277. Vivek Chem Fabs
  278. Vogelbusch Biocommodities
  279. VTU Group 
  280. W. B. Moore
  281. Wenzhou Chinz Machinery
  282. Wenzhou Daysly Technology
  283. Wenzhou Kosun Fluid Equipment
  284. Wenzhou Longqiang Machinery Tech
  285. Winkels 
  286. WUHAN CEKG TECH
  287. Wuxi Zhanghua Pharmaceutical Equipment
  288. XACT Systems
  289. Yadavaran Rafea Isfahan Research & Engineering
  290. ZAID STEEL
  291. Zellwerk
  292. ZETA
  293. Zhejiang JYSS Bio-Engineering
  294. Zhejiang Shuangzi Intelligent Equipment
  295. Zhengzhou Keda Machinery and Instrument Equipment
  296. Zhengzhou Laboao Instrument Equipment (LABAO)
  297. Zhengzhou Mingyi Instrument Equipment

Source 1: https://bioprocessintl.com/business/economics/total-global-biopharmaceutical-manufacturing-capacity-finally-shows-improved-productivity/
Source 2: https://www.pharmtech.com/view/pros-and-cons-single-use-bioreactors

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