Chromatography Instrumentation Market

Chromatography Instrumentation Market (Distribution by Type of Chromatography Instruments (Liquid Chromatography, Gas Chromatography, and Other Systems), Type of Consumable Formats (Prepacked Columns, Bottles / Bulk Resins and Other Formats), End Users (Pharmaceutical / Biotechnology Industries, Academic / Research Institutes and Other Industries) and Key Geographical Regions (North America, Europe, Asia-Pacific, Middle East and North Africa and Latin America): Industry Trends and Global Forecasts, 2023-2035

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Chromatography Instrumentation Market Overview 2023-2035

The global chromatography instrumentation market size is estimated to be worth $7.6 billion in 2023, growing at CAGR of 5.3% during the forecast period from 2023 to 2035.

Chromatography is a vital analytical technique used for the separation, identification, and purification of components in a mixture. It involves the distribution of each analyte between a mobile phase (liquid or gas) and a stationary phase (solid or liquid). This technique finds applications in various industries, including pharmaceutical, biotechnology, chemical, environmental, food, and petrochemical. In the pharmaceutical industry, there has been a growing demand for chromatography systems and consumables attributed to their use in qualitative and quantitative analysis of complex samples, large-scale translational research studies, precision medicine, virus research, and vaccine development. The outbreak of the COVID-19 pandemic has further fueled the growth of the global market for chromatography instrumentation and consumables, attributed to their adoption in various drug development processes and diagnostics.

Market Drivers

The primary factors driving the growth of the high performance liquid chromatography HPLC market include evolving process-specific needs across different industries, advanced features of chromatography techniques, and ongoing technological advancements. Various industries, such as pharmaceutical, forensic, and molecular biology, utilize chromatography techniques for purification, separation, identification, and analysis of compounds across multiple processes and scales. To meet the needs of these industries, chromatography companies are developing efficient chromatography instruments. Further, technological advancements in chromatography have led to the discovery of new techniques, such as silica-based monolith columns with reduced particle and column size for UPLC, automated UPLC, and advanced detection systems. Additionally, several advanced pre-packed columns have been launched in the market, which are more convenient and cost-effective.

Market Restraints

Market restraints in chromatography instrument market include the high cost of chromatography instrumentation and operations, strict regulatory guidelines and safety concerns, and lack of user training and expertise. The high operating cost of chromatography instruments, which involves the use of multiple consumables, solvents, and maintenance of instruments, restricts the use of such instruments by small companies and research institutions with financial constraints. Moreover, the use of chromatography requires a deep understanding of chromatography systems and expertise to operate the instruments. The lack of expertise and training can lead to inaccurate results, misinterpretation of data, and even instrumental damage in some cases. The high equipment costs and lack of skilled personnel for equipment handling are identified as key restraints in the chromatography instrumentation market.

Market Opportunities

The key market opportunities in the chromatography instrumentation market are the increasing demand for advanced analytical instruments, the growing pipeline of complex drug molecules, and the rising research activities in the pharmaceutical and biotech industry. This has led to the development of novel resins and convenient formats to fulfill specific purification needs for complex drug molecules. Additionally, the usage of chromatography is increasing across various research and industry processes, leading to a rise in demand for different types of chromatography consumables. As a result, chromatography consumable providers are actively expanding their product portfolio to meet the growing demand.

Chromatography Instrumentation Market Segments Overview

The chromatography instrumentation market forecast on the basis of type of chromatography instruments (liquid chromatography instrumentation, gas chromatography instrumentation, and other systems). On the basis of type of consumable formats (prepacked columns, bottles / bulk resins and other formats). On the basis of end users (pharmaceutical / biotechnology industries, academic / research institutes and other industries). By geographical regions, the market is analyzed across North America, Europe, Asia-Pacific, Middle East and North Africa and Latin America.

Type of Consumable Formats Analysis Section

Based on type of consumable formats, the chromatography instrumentation market is analyzed across prepacked columns, bottles / bulk resins and other formats. The chromatography market is currently led by bottle/bulk resins, followed by other formats. However, the market for pre-packed columns is expected to grow at a relatively high CAGR over the forecast period owing to their convenient and cost-effective advantages. This growth is driven by increasing demand for process development, affordable purification, and technological advancements in pre-packed chromatography columns, especially in the biopharmaceutical industry. Moreover, there has also been a surge in interest for pre-packed columns, which are seen as a convenient and cost-effective solution for purifying large quantities of proteins. With the increasing complexity of biologics, their purification needs are expected to rise, and chromatography consumable providers are anticipated to play a crucial role in developing novel resins and convenient formats suitable for various applications.

Regional Analysis Section

Based on region, the chromatography instrumentation market is analyzed across North America, Europe, Asia-Pacific, and LAMEA. Currently, North America and Europe account for more than 70% of the total market share in the field of chromatography. In recent years, there has been a significant increase in the demand for chromatography systems in North America. However, it is anticipated that in the coming years, the Asia-Pacific region will experience a much faster growth rate compared to other regions, given to the expected drug approvals and the growing need for separation processes in biopharmaceutical manufacturing.

Top Companies Engaged in Chromatography Instrumentation Market

Key chromatography companies that are engaged in chromatography instrumentation market are (in alphabetical order) Agilent Technologies, Bio-Rad Laboratories, Cytiva, PerkinElmer, Pall Corporation, Sartorius, Shimadzu, Shodex, ThermoFisher Scientific and Waters Corporation. This market report includes an easily searchable excel database of all the chromatography companies worldwide.

Chromatography Instrumentation Market Report Highlights

Report Segments Details
by Type of Chromatography Instruments 
  • Liquid Chromatography
  • Gas Chromatography
  • Other Systems
by Type of Consumable Formats
  • Prepacked Columns
  • Bottles / Bulk Resins 
  • Other Formats
by End Users
  • Pharmaceutical / Biotechnology Industries
  • Academic / Research Institutes 
  • Other Industries
Key Geographical Regions
  • North America (U.S., Canada, Mexico)
  • Europe (France, Germany, Italy, Spain, UK, Russia, Rest of Europe)
  • Asia-Pacific (China, Japan, India, South Korea, Australia, Thailand, Malaysia, Indonesia, Rest of Asia-Pacific)
  • LAMEA (Brazil, South Africa, Saudi Arabia, UAE, Argentina, Rest of LAMEA)
Key Market Players
  • Agilent Technologies
  • Bio-Rad Laboratories
  • Cytiva
  • PerkinElmer
  • Pall Corporation
  • Sartorius
  • Shimadzu
  • Shodex
  • ThermoFisher Scientific
  • Waters Corporation


Recent Developments in Chromatography Instrumentation Market

There has been recent activity in the chromatography instrumentation industry and some of the key developments have been mentioned below:

  • In July 2023, Valmet announced the acquisition of Process Gas Chromatography business of Siemens. The former company intends to strengthen its automation segment and process automation with the addition of the latter company’s process industry gas chromatography system and process analyzer systems to its offering.
  • In March 2023, US based Waters Corporation introduced its next generation HPLC chromatography system, Alliance™ iS, for its users in the QC laboratories.


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