DNA and Gene Cloning Services Market

DNA and Gene Cloning Services Market: Distribution by Type of Service Offered, Type of Gene, Company Size, End-User Industry and Key Geographical Regions: Industry Trends and Global Forecasts, 2022-2035

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DNA and Gene Cloning Services Market Overview

The DNA and gene cloning services market is estimated to be worth $2.1 billion in 2022 and is expected to grow at compounded annual growth rate (CAGR) of 16.0% during the forecast period. 

In 1973, a group of scientists reported that individual genes can be cloned and isolated by cleaving DNA enzymatically into DNA fragments. Over time, gene and DNA cloning has proved to be an important tool for researchers in their studies focused on genetics. The evolution of genetic engineering and cloning techniques has allowed for alterations in the genome of microorganisms, thereby enabling the production of substances having various research and therapeutic applications. Further, cloning can be used to produce gene therapies for the treatment of serious disease indications, such as cystic fibrosis, cancer, AIDS and others. It is interesting to note that gene cloning can be a potential solution to organ scarcity. It also plays an important role in synthesis of antibiotics, vitamins and hormones. Given the various applications of DNA and gene cloning, scientists have taken initiatives for constructing gene libraries having a collection of cloned DNA. However, the process of successful DNA cloning and gene cloning is associated with several challenges and complications, such as gene toxicity, requirement of a specific insert size or large vector, unstable DNA elements, and the presence of DNA secondary structures. In order to overcome these challenges and obtain a high-quality and stable finished product, the outsourcing of DNA and gene cloning is considered as a preferable option, among other alternatives, by companies engaged in DNA and gene cloning.  

Currently, several players offer services for DNA cloning and gene cloning. The DNA cloning and gene cloning services market is highly fragmented, featuring presence of various start-ups, mid-sized firms and well-established players. These players offer a wide range of services for DNA and gene cloning with different types of cloning methods. Further, it is worth mentioning that extensive research is being conducted for DNA cloning technologies; this is evident from more than 6,900 research articles that have been published for DNA cloning technologies in the past few years. In addition, more than 35 global events have been organized to discuss about the recent trends related to DNA and gene cloning. Driven by the growing demand for gene therapies, and the introduction and adoption of novel and advanced DNA cloning technologies, the DNA cloning and gene cloning services market is anticipated to witness steady market growth during the forecast period.

The context of DNA and Gene Cloning Services Market report, published by Roots Analysis

List of DNA and Gene Cloning Service Providers from the research report of Roots Analysis Current market landscape of DNA and Gene Cloning Service Providers domain, prepared by Roots Analysis

Key Companies in DNA and Gene Cloning Services Market

Examples of key companies engaged in DNA and gene cloning services market (which have also been profiled in this market report; the complete list of companies is available in the full report) include Aragen Life Sciences, Bio-Techne, Charles River Laboratories, Curia, Eurofins, GenScript, Integrated DNA Technologies, MedGenome, Sino Biological, Syngene and Twist Bioscience. This market report includes an easily searchable excel database of all the companies providing DNA and gene cloning services, worldwide.

Recent Developments in DNA and Gene Cloning Services Market:

Several recent developments have taken place in the field of DNA and gene cloning services market. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.

  • In March 2023, Elegen launched ENFINIA™ DNA in order to deliver up to 7kb of high-accuracy DNA.

Scope of the Report

The ‘DNA and Gene Cloning Services Market – Distribution by Type of Service Offered (Gene Synthesis, Custom Cloning, Sub-cloning and Others), Type of Gene (Standard Gene, Complex Gene and Others), Company Size (Small, Mid-sized and Large), End-User Industry (Academic and R&D, Pharmaceutical and Biotechnology Companies, and Others) and Key Geographies (North America, Europe, Asia-Pacific, Latin America and MENA): Industry Trends and Global Forecasts, 2022-2035’ market report features an extensive study of the current market landscape, market size, market share, market forecast, market outlook and future opportunities for the DNA and gene cloning services market. The market research report features an in-depth analysis, highlighting the capabilities of DNA cloning and gene cloning service providers. Amongst other elements, the market report features:

  • A detailed overview of the overall market landscape of DNA cloning and gene cloning service providers, based on several relevant parameters, such as information on their year of establishment, company size (in terms of employee count), region of headquarters (North America, Europe, Asia-Pacific and rest of the world). In addition to this, the chapter also features information on type of service(s) offered (gene synthesis, custom cloning, sub-cloning and others), cloning method(s) used (Restriction Enzyme Based Cloning, PCR Cloning, Ligation Independent Cloning, TA Cloning, Blunt End Cloning, Seamless Cloning and Recombinational Cloning), type of gene(s) cloned (standard gene and complex gene), expression system(s) used (bacterial, mammalian, insect and yeast), cloning vector(s) used (plasmids, bacteriophages, bacterial artificial chromosomes, yeast artificial chromosomes and mammalian artificial chromosomes) and end-user industry (academic and R&D, pharmaceutical and biotechnology companies, and others). 
  • An insightful benchmark analysis of the DNA and gene cloning service providers, located in North America, Europe, and Asia-Pacific and Rest of the World. The analysis compares the service providers on the basis of various parameters, such as number of cloning method(s) used, number of expression system(s) used, number of cloning vector(s) used and number of end-user(s). It also highlights the top players in various geographies.   
  • Elaborate profiles of the key players involved in providing services for DNA and gene cloning. Each profile features a brief overview of the company, its financial information (if available), details on its service portfolio and recent developments with an informed future outlook.
  • An in-depth analysis of patents related to DNA and gene cloning, filed / granted since 2017, based on several relevant parameters, such as patent type, publication year, application year, geographical location, Cooperative Patent Classification (CPC) symbols, emerging focus area, type of applicant, leading players (on the basis of number of patents), leading assignees (on the basis of number of patents) and patent benchmarking. In addition, it features a patent valuation analysis which evaluates the qualitative and quantitative aspects of the patents.
  • An analysis of more than 6,900 peer-reviewed, scientific articles related to research on DNA and gene cloning, which have been published between 2017 and 2022, including analysis based on parameters, such as year of publication, type of cloning, key focus area, popular journals (in terms of number of articles published in DNA and gene cloning services market), leading authors (in terms of number of articles published in DNA and gene cloning services market) and leading first authors (in terms of number of articles published in DNA and gene cloning services market).
  • An in-depth analysis of recent events (conferences / seminars / summits / trainings / webinars / workshops) related to DNA and gene cloning that were organized / planned. It features an analysis based on the year of occurrence of event, event platform, type of event, geographical distribution, emerging agendas / key focus areas, most active event speakers (in terms of number of events), seniority level of event speakers and geographical mapping of the upcoming events.
  • A case study on the DNA cloning kits developers, providing information and detailed analysis on kit components, number of reactions, type of cloning method used, type of fragment(s) cloned, cloning time, efficacy and kit shelf life. Further, it also includes a study on the DNA cloning reagents developers, along with a detailed analysis based on reagents’ unit size, concentration, components of reagents, exonuclease activity, product overhangs, heat inactivation temperature and storage temperature. In addition to this, the chapter concludes with the overview of geographical distribution of DNA cloning kits and reagents developers, along with DNA and gene cloning service providers.
Benchmarking analysis of DNA and Gene Cloning Service Providers, from Roots Analysis report This image presents review of scientific articles related to DNA and Gene Cloning This image provides information on patents that have been filed / granted related to DNA and Gene Cloning

The key objective of DNA and gene cloning services market report is to provide a detailed market analysis in order to estimate the existing market size, market value, statistics and future opportunity for DNA and gene cloning services market during the forecast period. We have provided informed estimates of the likely evolution of the market in the short to mid-term and long term, for the forecast period 2022-2035. Our year-wise projections of the current and future opportunity have further been segmented based on relevant parameters, such as [A] type of service offered (gene synthesis, custom cloning, sub-cloning and others), [B] type of gene (standard gene, complex gene and others), [C] company size (small, mid-sized and large), [D] end-user industry (academic and R&D, pharmaceutical and biotechnology companies and others), [E] key geographical regions (North America, Europe, Asia-Pacific, Latin America and MENA). To account for future uncertainties in the market and to add robustness to our model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic tracks of the market’s evolution.

The opinions and insights presented in the market research report were also influenced by discussions held with senior stakeholders in the industry.

This image highlights the global events undertaken by players engaged in DNA and Gene Cloning Services Market The current and future market trends of DNA and Gene Cloning Services Market according to Roots Analysis The market segments of DNA and Gene Cloning Services domain based on the research report of Roots Analysis

Frequently Asked Questions

Question 1: What is DNA and Gene cloning?

Answer: DNA and gene cloning refers to the process of creating copies of a single strand of DNA or gene of interest by employing genetic engineering techniques.

Question 2: How big is the DNA and gene cloning services market?

Answer: The DNA and gene cloning services market size is estimated to be worth $2.1 billion in 2022.

Question 3: What is the projected market growth of the DNA and gene cloning services market?

Answer: The DNA and gene cloning services market is expected to grow at compounded annual growth rate (CAGR) of 16% during the forecast period 2022 - 2035.

Question 4: Who are the leading companies in the DNA and gene cloning services market?

Answer: Examples of key companies engaged in DNA and gene cloning services market (which have also been profiled in this market report; the complete list of companies is available in the full report) include Aragen Life Sciences, Bio-Techne, Charles River Laboratories, Curia, Eurofins, GenScript, Integrated DNA Technologies, MedGenome, Sino Biological, Syngene and Twist Bioscience.

Question 5: How many research articles have been published related to DNA and gene cloning?

Answer: Since 2018, over 6,900 research articles have been published related to DNA and gene cloning globally.

Question 6: Which region is the hub for companies providing DNA and gene cloning services?

Answer: North America presently harbors the majority of the companies providing DNA and gene cloning services, with close to 60% of the companies being established in this region.

Question 7: Which type of expression system is primarily utilized by companies engaged in the DNA and gene cloning services market?

Answer: Majority (53%) of the DNA and gene cloning service providers utilize bacterial expression systems for cloning DNA and gene fragments.

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