Single Use Bioreactors Market

Single Use Bioreactors Market (3rd Edition) - Distribution by Type of Bioreactor, Scale of Operation, Type of Cell Culture, Type of Biologics Synthesized, Application Area, End-users, and Key Geographical Regions: Industry Trends and Global Forecasts, 2023-2035

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Report Description

Single Use Bioreactors Market Overview

The global single use bioreactors market is estimated to be worth USD 1.3 billion in 2023 and is expected to grow at compounded annual growth rate (CAGR) of ~17% during the forecast period. Over the past few years, biopharmaceuticals have gained significant attention owing to their therapeutic efficacy. In fact, in the past two decades, over 170 biologics have received the USFDA approval, while over 10,000 biologics are currently under different stages of development. It is a well-known fact that the commercial and clinical scale manufacturing of these complex biomolecules requires highly specialized bioprocessing equipment. Conventionally, stainless steel bioreactors were the preferred choice for biologics manufacturing; however, to fulfill the need for high quality antibodies, cell therapies, gene therapies and other bio-therapeutics, a gradual shift towards the use of a single use bioreactor has been observed. A single-use bioreactor, also known as disposable bioreactor, employs single use bioreactor bags instead of stainless steel culture vessel for the manufacturing of various biologics. Single-use bioreactors offer various advantages over conventional bioreactors; these include cost efficiency (~40%), shorter production timeline (~35%), reduction in energy and water consumption (45%-50%), better product yield and low risk of contamination. Owing to the aforementioned benefits, various stakeholders have adopted disposable bioreactors for the manufacturing of biologics. Moreover, many single use bioreactor manufacturers are focusing on incorporating a variety of advanced features, including provisions for alerts / alarms, electronic process logs, built-in system process control sensors, touch screens, remote monitoring features, and advanced safety provisions in their proprietary offerings. In order to address the growing demand for biologics, such companies are working towards manufacturing more efficient single use bioreactors for global markets and thereby, supporting the adoption of single use technology. The global market for single use bioreactors is anticipated to witness substantial growth during the forecast period.

The image provides contedxt of single user bioreactors market. Owing to the rising demand for biologics and various benefits associated with single-use systems, the biopharmaceutical industry is gradually shifting its focus from conventional bioreactors to more advanced disposable bioreactors This image provides a list of single use bioreactors. Currently, over 60 companies claim to offer more than 260 cutting-edge single-use bioreactors in order to cater to the rising demand for biopharmaceuticals, across the globe This image highlights single-use bioreactors market landscape. The market is primarily characterized by the presence of well-established players that offer single-use bioreactors for processing of various cell cultures used for the production of different types of biologics

Key Market Insights

The Single Use Bioreactors Market (3rd Edition) – Distribution by Type of Bioreactor (Stirred Tank, Pneumatically Mixed, Rocker / Rotating, Wave-Induced, Paddle Sleeve, Fixed-Bed, Hollow Fibre, Diffusion, and Orbitally Shaken), Scale of Operation (Lab, Clinical and Commercial), Type of Cell Culture (Mammalian, Insect, Microbial, Viral, Plant and Bacterial), Type of Biologics Synthesized (Vaccine, Monoclonal Antibody, Recombinant Protein, Stem Cell, Cell Therapy, and Gene Therapy), Application Area (Cancer Research, Stem Cell Research, Tissue Engineering / Regenerative Medicine, Drug Discovery / Toxicity Testing and Others), End-users (Biopharmaceutical / Pharmaceutical Industries, Academic / Research Institutes), and Key Geographical Regions (North America, Europe, Asia-Pacific, Latin America, and Middle East and North Africa): Industry Trends and Global Forecasts, 2023-2035 report features an extensive study of the current market landscape, market size and future opportunities associated with this industry, for the given forecast period. The market research report highlights the efforts of several stakeholders engaged in this emerging and rapidly evolving segment of the biopharmaceutical industry. Key takeaways from the study of single-use bioreactor market are briefly discussed below.

Rising Interest in Large Scale Disposable Bioreactors for Single use Bioprocessing 

Several breakthroughs in the biotechnology industry, over the last few years, have provided a considerable boost to the overall growth of biopharmaceutical industry. However, in 2022, owing to the increasingly stringent regulatory guidelines related to biomanufacturing process, the new drug approvals declined by around 25%. Hence, the growing demand for quality products has encouraged biologic manufacturers to adopt single-use bioreactor, a more advanced and long-term solution. These disposable bioreactors are cost effective and have the capability to provide operational flexibility as compared to the conventional technologies.  In April 2023, mAbxience, a Spanish CDMO installed a 4000 L single-use bioreactor manufactured by ABEC, at its Leon facility. Earlier, in 2018, WuXi Biologics had also installed these 4,000 L bioreactors for large scale single use bioprocessing at their Wuxi city manufacturing facility. It is worth mentioning that ABEC, Henan Lanphan, and Thermo Fisher Scientific are amongst the key players that have launched the largest single-use bioreactors with capacity of more than 4,000 L.

The ongoing technological advancements focused on the development of improved versions of biosensors and single use bioreactor bags are likely to encourage the biopharmaceutical companies to adopt disposable bioreactor for bioprocessing, representing a lucrative opportunity for companies engaged in this growing market.

Current Single use Bioreactors Market Landscape

The single-use bioreactor market features a mix of large, mid-sized and small companies that have the required expertise to provide various types of single use bioreactors for the production of biologics. At present, more than 260 single-use bioreactors have been developed by over 60 industry stakeholders to enable the manufacturing of biologics. It is worth highlighting that majority of the single use bioreactors (~60%) offered by various manufacturers are stirred tank bioreactors. This can be attributed to the fact that stirred tank bioreactors are less likely to cause damage to the cell cultures, as these bioreactors possess optimal blade diameters and agitation speed. It is worth highlighting that constant evolution of disposable bioreactors is likely to support the development of novel and more efficacious biologics, in turn, contributing to the substantial growth of single use bioreactor market, during the forecast period.

Key Advantages Associated with Single use Bioreactors Used for the Production of Wide Variety of Biopharmaceuticals

Single use bioreactors offer various advantages over conventional stainless steel bioreactors. These advantages include ~50% reduction in total energy and water consumption and ~40% cost saving by elimination of cleaning and sterilization processes after every batch production. Apart from the aforementioned benefits, use of single-use bioreactors also lowers the risk of cross-contamination, making these disposable bioreactors more user-friendly and efficient. Further, these systems are portable and have a smaller footprint as compared to the conventional systems, which reduces the total space required for installation. Owing to the aforementioned benefits associated with single use bioreactors, we believe that there is significant growth opportunity for the companies engaged in this industry during the forecast period.

Key Challenges Associated with the Adoption of Single use Bioreactors

One of the key challenges faced by single use bioreactor manufacturers is the reluctance of industry players to adopt these novel systems. This can be attributed to the expenses that they are likely to incur while switching to a new technology. Although, disposable bioreactors have gained significant popularity in the recent past owing to their advantages, they still pose a reasonable risk of contamination from extractables and leachables. Single use bioreactors are developed using plastic materials that can release organic or inorganic chemicals into liquid pharmaceutical products under high temperature and pressure. Potentially, these chemicals can jeopardize the safety of drug products and well-being of the patient. Further, insufficient supply of raw materials, single use components and assemblies can be another roadblock in this industry. While disposable bioreactor manufacturers are striving to tackle these challenges through innovation in design and manufacturing methods, the current inability of single use bioreactors to operate at volume greater than 6,000 L for large scale production, remains another pressing concern.

Single use Bioreactor Market Size: Stirred Tank Single-Use Bioreactor Segment holds the Largest Market Share

The global single use bioreactors market is likely to be worth around USD 1.3 billion in 2023. Driven by the rising demand for novel biopharmaceuticals, high adoption rates of precision medicine, along with advancement in bioprocessing technologies, the single use bioreactor market is anticipated to grow at a CAGR of 17%, during the forecast period 2023-2035. Currently, the global market for single-use bioreactors is dominated by companies providing stirred tank bioreactors. The single-use stirred tank bioreactor segment captures 80% of the market share and it is likely to grow at a CAGR of 14% during the forecast period.

Additionally, in terms of type of cell culture, the mammalian cell cultures are anticipated to hold more than 40% share of the single use bioreactor market. It is worth mentioning that over 80% of the disposable bioreactors are suitable for processing mammalian cell cultures.

North America and Europe to Compete for the Largest Share of Single use Bioreactors Market

Overall, the companies based / headquartered in North America and Europe capture 75% share of the current market. Companies, such as ABEC, Eppendorf, Merck Millipore, PBS Biotech and Thermo Fisher Scientific offer a wide range of single use bioreactors. These companies have in-house single use bioreactor portfolio, with different types of bioreactors, such as stirred tank bioreactor, wave / induced bioreactor and pneumatically mixed bioreactor. Furthermore, Asia Pacific region is witnessing huge growth in biopharmaceutical market, with a number of CMOs setting up new facilities or announcing expansions in countries such as Singapore and Korea. In May 2023, Merck KgaA announced its plan to build a bioprocessing center in Daejeon City, Korea. Further, several companies, including WuXi Biologics have invested for biopharmaceutical manufacturing in Singapore. Moreover, a number of manufacturing facilities are being set up in Asia Pacific region, to meet the growing local demand for biologics from the consumers as well as the demand from small biopharmaceutical startups, which are likely to drive the market for single use bioreactors over the coming years.

Bioreactor manufacturers are continuously putting efforts to improve their product portfolio in order to address the challenges related to biomanufacturing by delivering innovative disposable bioreactors to the pharmaceutical industry. Given the ongoing efforts of stakeholders, we believe that the single use bioreactor market is poised to witness significant growth over the forecast period.

Partnership Activity in Single-use Bioreactor Market

In recent years, several partnerships have been established by industry stakeholders, in order to consolidate their presence in this field and enhance their capabilities and product portfolio to meet the growing demand for biotherapeutics. In fact, the partnership activity in this domain grew at a CAGR of ~15% over the past five years. Interestingly, most of the agreements were supply and technology integration agreements. The domain also witnessed a significant number of mergers and acquisitions during the past five years, indicating the growing interest of stakeholders in this industry.

In January 2023, Thermo Fisher Scientific entered into a manufacturing agreement with ASLAN Pharmaceuticals for the manufacturing of eblasakimab for phase III clinical studies. Sartorius Stedim Biotech has signed several deals in the past few years to provide innovative single use systems to various biomanufacturers with an aim to support biologics manufacturing. Given the trends in this market, we believe that such deals are likely to drive the single use bioreactors market during the forecast period.

Key Emerging Trends in the Single use Bioreactor Market

Stakeholders engaged in this industry are identifying new ways to enhance efficiency and reduce turnaround time. This has led to various technological advancements in this field, which include alerts / alarms, built-in system process control sensors, electronic process logs, remote monitoring features, touch screens, and advanced safety provisions, that have demonstrated increase in efficiency and quality of the process. Further, the integration of controllers and automated systems is another advancement that allows to keep the process parameters within the desired and acceptable limits, but also make the necessary adjustments, while minimizing the risks of human errors. It is worth mentioning that the single use bioreactors market is also witnessing the adoption of bioprocessing 4.0 solutions that leverages machine learning (ML) and artificial intelligence (AI) for real-time process monitoring. Such advancements are anticipated to result into better yields, reduced waste, and development of higher quality biologics. The ongoing efforts in the field of single use technologies will support the growth of the single use bioreactors market over the forecast period.

Leading Companies Engaged in Single Use Bioreactors Market

Examples of key companies engaged in this industry include (which have also been captured in this report) Applikon Biotechnology, Biolinx Labsystems, Celartia, Cell Culture Company, Cellexus, Cercell, CESCO Bioengineering, Cytiva, Eppendorf, Merck Millipore, Pall Corporation, PBS Biotech, PerfuseCell, ProlifeCell, Sartorius Stedim Biotech, Solaris Biotech, Synthecon and Thermo Fisher Scientific. This market report includes an easily searchable excel database of the single use bioreactor manufacturers worldwide.

Recent Developments in Single-use Bioreactors Market

Several recent developments have taken place in the field of single-use bioreactors. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.

  • In August 2023, Sartorius and Repligen Corporation announced the launch of an integrated bioreactor system that incorporates Repligen XCell® ATF upstream intensification technology into Sartorius’ Biostat STR® bioreactor, simplifying intensified seed train and N perfusion implementation for biopharmaceutical manufacturers. 
  • In August 2023, Sartorius entered into a partnership wih Emerson to integrate Sartorius’s Biostat STR® Generation 3 family of bioreactors with Emerson’s DeltaVTM distributed control system (DCS). 
  • In June 2023, Cytiva collaborated with Culture Biosciences to advance innovation in upstream bioprocessing by providing customers greater access to predictive and robust scale-up capabilities. 
The image provides single-use bioreactors competitive landscape. In pursuit of gaining a competitive edge, single-use bioreactor manufacturers are upgrading their existing capabilities and enhancing their product portfolios to achieve better, cost-effective and faster biomanufacturing The snapshot highlights various single-user bioreactor companies profiled in the market report. Several well-established stakeholders, located across various regions of globe, have taken multiple initiatives in single-use bioreactor industry to cater to the demand for novel biopharmaceuticals This image provides details on partnerships that have been forged in the disposable bioreactor market. The growing interest of biologic manufacturers in single-use bioreactors is evident from the rise in partnership activity; more than 50% of the deals were inked specifically for stirred tank bioreactors

Scope of the Report

The market report presents an in-depth analysis of the various firms / organizations that are engaged in this market, across different segments as defined in the below table:

Key Report Attributes Details

Base Year

2022

Forecast Period

2023 – 2035

Market Size 2023

$1.3 billion

CAGR

17%

Type of Bioreactor

  • Stirred Tank
  • Pneumatically Mixed
  • Rocker / Rotating
  • Wave-Induced
  • Paddle Sleeve
  • Fixed-Bed
  • Hollow Fiber
  • Diffusion
  • Orbitally Shaken

Scale of Operation

  • Lab
  • Clinical
  • Commercial

Type of Cell Culture

  • Mammalian
  • Insect
  • Microbial
  • Viral
  • Plant
  • Bacterial

Type of Biologics Synthesized

  • Vaccine
  • Monoclonal Antibody
  • Recombinant Protein
  • Stem Cell
  • Cell Therapy
  • Gene Therapy

Application Area

  • Cancer Research
  • Stem Cell Research
  • Tissue Engineering / Regenerative Medicine
  • Drug Discovery / Toxicity Testing
  • Others

End-Users

  • Biopharmaceutical / Pharmaceutical Industries
  • Academic / Research Institutes

Key Geographical Regions

  • North America
  • Europe
  • Asia-Pacific
  • Middle East and North Africa (MENA)
  • Latin America

Key Companies Profiled

  • Applikon Biotechnology
  • Biolinx Labsystems
  • Celartia
  • Cell Culture Company 
  • Cellexus
  • Cercell
  • CESCO Bioengineering
  • Cytiva
  • Eppendorf
  • Merck Millipore
  • Pall Corporation
  • PBS Biotech
  • PerfuseCell
  • ProlifeCell
  • Sartorius Stedim Biotech
  • Solaris Biotech
  • Synthecon 
  • Thermo Fisher Scientific

(Full list of 60+ companies captured in the market landscape analysis of the report)

Customization Scope

15% Free Customization Option

PowerPoint Presentation (Complimentary)

Available

Excel Data Packs (Complimentary)

  • Market Landscape Analysis
  • Key Insights
  • Company Competitiveness Analysis
  • Partnerships and Collaborations
  • Product Competitiveness Analysis
  • Brand Positioning Analysis
  • Patent Analysis
  • Market Forecast and Opportunity Analysis

The market report presents an in-depth analysis, highlighting the capabilities of various companies engaged in this industry, across different regions. Amongst other elements, the research report includes:

  • An executive summary of the insights captured during our research, offering a high-level view on the current state of the single use bioreactors market and its likely evolution in the mid-long term.
  • A general introduction to single use bioreactors, highlighting key technology specifications and offering details related to some of the current and future trends in this industry. It also includes a comparative summary of conventional stainless steel bioreactor and single use bioreactor. The chapter features insights related to prevalent regulatory standards, existing challenges and elaborates on the various advantages of single use bioreactors.
  • A detailed assessment of various single-use bioreactors that are either commercialized or under development. It includes detailed analysis of the overall market landscape of single use bioreactors based several relevant parameters, such as type of bioreactor (diffusion, fixed bed bioreactor, hollow fibers, pneumatically mixed, rotating bioreactor, stirred tank  bioreactor, and wave induced / rocking bioreactors), scale of operation (lab, clinical and commercial), typical working volume, stirrer speed, weight of the bioreactor, advanced display / control features (alarm system, build-in system, electronic-log, remote monitoring and touch screen), mode of operation (batch, fed-batch and continuous), type of culture (2D culture and 3D culture), type of cell culture (insect, mammalian, microbial, plant, viral and others), type of biologic synthesized (cell therapies, gene therapies, monoclonal antibodies, recombinant proteins, stem cells, vaccines and others), end-users (academic, CRO, CMO and pharmaceutical / biopharmaceutical). In addition, the chapter presents the overall market landscape of companies developing single-use bioreactors, including information on their year of establishment, company size, and location of headquarters.
  • A contemporary market trend analysis, featuring a hybrid chart representation of companies engaged in this industry based on their company size and location of headquarters, a stacked bar chart representation of company size and type of single use bioreactor, a stacked bar chart representation of type of single use bioreactor and mode of operation, a heat map representation analyzing the data on the basis of the type of single use bioreactor and type of biologic synthesized, a heat map representation analyzing the data on the basis of the scale of operation, type of cell culture and type of biologic synthesized, and a world map representation highlighting the regional distribution of companies engaged in single use bioreactors market, based on the location of their headquarters.
  • An insightful four-dimensional bubble chart representation, highlighting the competitiveness of single use bioreactor manufacturers, taking into consideration the supplier strength (based on expertise of the manufacturer), product portfolio diversity and portfolio strength.
  • Tabulated profiles of key companies based in North America, Europe, Asia-Pacific and Rest of the World (shortlisted based on a proprietary criterion) engaged in developing single use bioreactors. Each company profile features a brief overview of the company, along with its financial information (if available), product portfolio, recent developments and an informed future outlook.
  • An analysis of the recent partnerships and collaborations related to single use bioreactors, which have been established during period 2007 and 2023 (till January), based on several parameters, such as year of agreement, type of partnership (mergers / acquisitions, product / technology integration agreements, product distribution agreements, product / technology development agreements, service alliances, supply agreements, supply / distribution agreements and others), focus area (capacity expansion, geographical expansion, incorporation of automation solutions, product portfolio expansion, product development / testing, process optimization / improvement, research and development, supply of product and others), type of partner (industry and non-industry), type of biologic synthesized (antibodies, cell lines, cell therapies, gene therapies, plasmid DNA, proteins, vaccines, viral vectors and others), type of bioreactor involved (pneumatically mixed, rotating bioreactor, stirred tank bioreactor, wave induced / rocking bioreactor and others), location of facility, expanded bioreactor capacity and most active players. It also provides the regional distribution of the companies involved in these agreements.
  • A detailed product competitiveness analysis of single use bioreactors, taking into consideration several relevant parameters, such as the supplier strength (based on company’s overall experience) and product competitiveness (calculated using status of development, scale of operation, type of cell culture, type of biologics synthesized, mode of operation, working volume and weight). In order to make relevant comparisons, we segregated the aforementioned products into peer groups based on the type of bioreactor (stirred tank bioreactors, fixed-bed bioreactors, wave induced / rocking bioreactors and other bioreactors).
  • An opinion on the relative popularity of the respective brands of key industry stakeholders (companies offering single-use bioreactors), based on prevalent trends. The primary purpose of this analysis is to develop an understanding on how the brands of companies are currently perceived / positioned in different market segments, relative to their competitors, based on several relevant parameters, such as portfolio strength (based on number of products), portfolio diversity (working volume, stirrer speed, weight, type of biologics synthesized and type of cell culture), years of experience, number of patents and number of partnerships. In addition, the framework can assist companies in determining improvement areas by identifying gaps within their existing capabilities, as well as recognize ways to gain competitive advantage in the mid to long term. 
  • An overview of the various patents that have been filed / granted for single use bioreactors. Additionally, it features a detailed analysis of these patents, highlighting the prevalent trends related to the type of patent, publication year, application year, patent jurisdiction, focus area, Cooperative Patent Classification (CPC) symbols and type of applicant. Further, the chapter highlights the leading industry and non-industry players (in terms of number of patents filed / granted). In addition, it includes an informed patent benchmarking analysis, along with an analysis of the relative valuation of patents filed / granted for single use bioreactors based on parameters, such as patent age, region in which the patent was filed / granted and number of citations.
  • A case study on the key technological innovations, such as built-in system control sensors, advanced alarm systems, electronic-log records, touch screens, real-time tracking, remote monitoring and advanced mixing technologies, that have been introduced in the single use bioreactors industry. It also highlights the ongoing progression of automation in single use bioreactor for better bioprocess development. 
  • A discussion on affiliated trends, key drivers and challenges, under a SWOT framework, which are likely to impact the industry’s evolution, including a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall single use bioreactors industry.
  • A case study on the market landscape of bioprocess controllers and automation systems, providing information on scale of operation (laboratory, clinical, and commercial), key features (scalability / ease to use, visual data display, remote accessibility, built-in system control sensors, expansive I/O compatibility and provisions for alarms / alerts), compatibility with bioreactor system (stirred tank (glass), single-use bioreactor, stirred tank (steel), fermenter, rocking motion), type of bioprocess (batch, fed-batch and perfusion), and type of process controlled (cell cultivation and microbial fermentation). In addition, the chapter presents details of companies involved in the development of bioprocess control software, upstream and downstream controllers, including information on their respective year of establishment, company size, and location of headquarters.
The image highlights disposable bioreactor competitive landscape. Industry stakeholders are actively focusing on the integration of advanced features in their respective systems, in order to maintain their competitive position in the market The infographic highlights brand positioning of various single use bioreactor companies. To cater to the increasing demand for biologics, a number of players have stepped up to introduce innovative and advance single-use bioreactors, establishing a strong brand position Single-use-Bioreactors-Market-Patent-Analysis-thumb

One of the key objectives of the market report was to estimate the current opportunity and the future growth potential of the global single use bioreactor market over the forecast period. We have provided an informed estimate on the likely evolution of the market for the period 2023-2035. Our year-wise projections of the current and forecasted market have been further segmented based on relevant parameters, such as type of bioreactor (stirred tank, pneumatically mixed, rocker / rotating, wave-induced, paddle sleeve, fixed-bed, hollow fiber, diffusion, and orbitally shaken), scale of operation (lab, clinical and commercial), type of cell culture (mammalian, insect, microbial, viral, plant and bacterial), type of biologic synthesized (vaccine, monoclonal antibody, recombinant protein, stem cell, cell therapy, and gene therapy), application area (cancer research, stem cell research, tissue engineering / regenerative medicine, drug discovery / toxicity testing and others), end-users (biopharmaceutical / pharmaceutical industries, academic / research institutes), and key geographical regions (North America, Europe, Asia-Pacific, Latin America, and Middle East and North Africa). In order to account for future uncertainties associated with some of the key parameters and to add robustness to our model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic scenarios of the industry’s evolution.

The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders in this domain. The research report features detailed transcripts of interviews held with the following individuals:

  • Shane Kilpatrick (Founder and Chief Executive Officer, Membio)
  • Justin Cesmat (Manager, Bioprocessing, Distek)
  • Bradley Maykow (Quality and Products Manager, Refine Technology)
  • Per Stobbe (Chief Executive Officer, CerCell)
  • Torsten Due Bryld (Global Director of Sales Support, CelVivo)

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this market report are in USD, unless otherwise specified.

This image provides provides our estimates on single use bioreactors market. The single-use bioreactors market is projected to grow at a CAGR of ~17%, till 2035; the forecasted opportunity is likely to be distributed across different scales of operation, types of bioreactors and types of cell cultures The image provides single use bioreactors market segments. The growing demand for different types of biologics is anticipated to drive the growth of single-use bioreactors market; Asia-Pacific is anticipated to be the fastest growing region  

Frequently Asked Questions

Question 1: What is a single use bioreactor?

Answer: Single use bioreactors are those bioreactors that use disposable bags instead of reusable stainless steel cultural vessels.

Question 2: What is the market size of single use bioreactors?

Answer: The global single use bioreactor market is anticipated to be worth around USD 1.3 billion in 2023.

Question 3: What are the factors driving the single use bioreactors market?

Answer: Advancements in bioprocessing technologies and rise in demand for novel biopharmaceuticals are the key factors driving the global single use bioreactors market.

Question 4: Who are the key players in single use bioreactors market?

Answer: Presently, more than 60 companies are engaged in single use bioreactors market, worldwide. Examples of top players engaged in this industry (full list available in the report) include Applikon Biotechnology, Biolinx Labsystems, Celartia, Cell Culture Company , Cellexus, Cercell, CESCO Bioengineering, Cytiva, Eppendorf, Merck Millipore, Pall Corporation, PBS Biotech, PerfuseCell, ProlifeCell, Sartorius Stedim Biotech, Solaris Biotech, Synthecon and Thermo Fisher Scientific.

Question 5: Which region has the largest share in single use bioreactors market?

Answer: North America and Europe captures around 75% of the current single use bioreactors market, followed by Asia-Pacific.

Question 6: Which type of single use bioreactor has the largest share in the global single use bioreactor market?

Answer: Currently, the global single use bioreactor market is dominated by the companies providing stirred tank single use bioreactors. The stirred tank bioreactor market captures 80% market share and it is likely to grow at a CAGR of 14%, during the forecast period.

Question 7: Which are the leading market segments in global single use bioreactor market, in terms of type of biologic synthesized?

Answer: Our estimates suggest that monoclonal antibodies capture more than 25% share in the overall global single use bioreactor market.

Question 8: What is the growth rate of single use bioreactors market?

Answer: The global single use bioreactor market is projected to grow at a CAGR of ~17% during the forecast period.

Contents

Table Of Contents

1. PREFACE
1.1. Introduction
1.2. Key Market Insights
1.3. Scope of the Report
1.4. Research Methodology
1.5. Frequently Asked Questions
1.6. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION 
3.1. Chapter Overview
3.2. Overview of Single-use Bioreactors 
3.2.1. Historical Evolution
3.2.2. Single-use versus Traditional Bioreactors
3.3. Types of Single-use Bioreactors 
3.3.1. Based on Cell Culture
3.3.2. Based on Agitation Mechanism
3.4. Advantages of Single-use Bioreactors 
3.5. Key Applications Areas 
3.6. Prevalent Regulatory Standards
3.7. Challenges Associated with Single-use Bioreactors 
3.8. Concluding Remarks

4. MARKET LANDSCAPE 
4.1. Chapter Overview
4.2. Single-use Bioreactors: Overall Market Landscape
4.2.1. Analysis by Type of Bioreactor
4.2.2. Analysis by Scale of Operation 
4.2.3. Analysis by Working Volume (Liters)
4.2.4. Analysis by Stirrer Speed (RPM)
4.2.5. Analysis by Weight of Bioreactor (Kg)
4.2.6. Analysis by Advanced Display / Control Features 
4.2.7. Analysis by Mode of Operation
4.2.8. Analysis by Type of Culture
4.2.9. Analysis by Type of Cell Culture 
4.2.10. Analysis by Type of Biologics Synthesized
4.2.11. Analysis by End-users

4.3. Single-use Bioreactor Manufacturers: Overall Market Landscape
4.3.1. Analysis by Year of Establishment
4.3.2. Analysis by Company Size
4.3.3. Analysis by Location of Headquarters (Region)
4.3.4. Analysis by Location of Headquarters (Country)

4.4. Leading Manufacturers: Analysis by Number of Products

5. KEY INSIGHTS
5.1. Chapter Overview
5.2. Analysis by Company Size of Manufacturer and Type of Single-use Bioreactor 
5.3. Analysis by Type of Single-use Bioreactor and Mode of Operation
5.4. Analysis by Type of Single-use Bioreactor and Type of Biologics Synthesized
5.5. Analysis by Scale of Operation, Type of Cell Culture and Type of Biologics Synthesized
5.6. Analysis by Company Size and Location of Headquarters 
5.7. Analysis by Location of Headquarters

6. COMPANY COMPETITIVENESS ANALYSIS
6.1. Chapter Overview
6.2. Methodology
6.3. Assumptions / Key Parameters
6.4. Single-use Bioreactor Manufacturers: Company Competitiveness Analysis 
6.4.1. Small Companies
6.4.2. Mid-sized Companies
6.4.3. Large Companies

7. SINGLE-USE BIOREACTOR MANUFACTURERS IN NORTH AMERICA: COMPANY PROFILES
7.1. Chapter Overview
7.2.1. Celartia
7.2.1.1. Company Overview
7.2.1.2. Product Portfolio
7.2.1.3. Recent Developments and Future Outlook

7.2.2. Cell Culture Company
7.2.2.1. Company Overview
7.2.2.2. Product Portfolio
7.2.2.3. Recent Developments and Future Outlook

7.2.3. Cytiva
7.2.3.1. Company Overview
7.2.3.2. Financial Information
7.2.3.3. Product Portfolio
7.2.3.4. Recent Developments and Future Outlook

7.2.4. Merck Millipore
7.2.4.1. Company Overview
7.2.4.2. Financial Information
7.2.4.3. Product Portfolio
7.2.4.4. Recent Developments and Future Outlook

7.2.5. Pall Corporation
7.2.5.1. Company Overview
7.2.5.2. Financial Information
7.2.5.3. Product Portfolio
7.2.5.4. Recent Developments and Future Outlook

7.2.6. PBS Biotech
7.2.6.1. Company Overview
7.2.6.2. Product Portfolio
7.2.6.3. Recent Developments and Future Outlook

7.2.7. Synthecon
7.2.7.1. Company Overview
7.2.7.2. Product Portfolio
7.2.7.3. Recent Developments and Future Outlook

7.2.8. Thermo Fisher Scientific
7.2.8.1. Company Overview
7.2.8.2. Financial Information
7.2.8.3. Product Portfolio
7.2.8.4. Recent Developments and Future Outlook

8. SINGLE-USE BIORECTOR MANUFACTURERS IN EUROPE, ASIA-PACIFIC AND REST OF THE WORLD: COMPANY PROFILES
8.1. Chapter Overview
8.2. Leading Players based in Europe
8.2.1. Applikon Biotechnology
8.2.1.1. Company Overview
8.2.1.2. Product Portfolio
8.2.1.3. Recent Developments and Future Outlook

8.2.2. Cellexus
8.2.2.1. Company Overview
8.2.2.2. Product Portfolio
8.2.2.3. Recent Developments and Future Outlook

8.2.3. CerCell
8.2.3.1. Company Overview
8.2.3.2. Product Portfolio
8.2.3.3. Recent Developments and Future Outlook

8.2.4. Eppendorf
8.2.4.1. Company Overview
8.2.4.2. Financial Information
8.2.4.3. Product Portfolio
8.2.4.4. Recent Developments and Future Outlook

8.2.5. PerfuseCell
8.2.5.1. Company Overview
8.2.5.2. Product Portfolio
8.2.5.3. Recent Developments and Future Outlook

8.2.6. ProlifeCell
8.2.6.1. Company Overview
8.2.6.2. Product Portfolio
8.2.6.3. Recent Developments and Future Outlook

8.2.7. Sartorius Stedim Biotech
8.2.7.1. Company Overview
8.2.7.2. Financial Information
8.2.7.3. Product Portfolio
8.2.7.4. Recent Developments and Future Outlook

8.2.8. Solaris Biotech
8.2.8.1. Company Overview
8.2.8.2. Product Portfolio
8.2.8.3. Recent Developments and Future Outlook

8.3. Leading Players based in Asia-Pacific and Rest of the World
8.3.1. Biolinx Labsystems 
8.3.1.1. Company Overview
8.3.1.2. Product Portfolio
8.3.1.3. Recent Developments and Future Outlook

8.3.2. CESCO Bioengineering
8.3.2.1. Company Overview
8.3.2.2. Product Portfolio
8.3.2.3. Recent Developments and Future Outlook

9. PARTNERSHIPS AND COLLABORATIONS 
9.1. Chapter Overview
9.2. Partnership Models

9.3. Single-use Bioreactors: List of Partnerships and Collaborations 
9.3.1. Analysis by Year of Partnership
9.3.2. Analysis by Type of Partnership
9.3.3. Analysis by Year and Type of Partnership
9.3.4. Analysis by Focus Area
9.3.5. Analysis by Year of Partnership and Focus Area
9.3.6. Analysis by Type of Partner
9.3.7. Analysis by Type of Biologics Synthesized
9.3.8. Analysis by Type of Bioreactor Involved
9.3.9. Analysis by Location of Facility (Country) and Expanded Bioreactor Capacity 
9.3.10. Most Active Players: Analysis by Number of Partnerships

9.3.11. Analysis by Geography
9.3.11.1. Local and International Agreements
9.3.11.2. Intracontinental and Intercontinental Agreements

10. PRODUCT COMPETITIVENESS ANALYSIS
10.1. Chapter Overview
10.2. Methodology 
10.3. Assumptions / Key Parameters
10.4. Single-use Bioreactors: Product Competitiveness Analysis
10.4.1. Stirred Tank Single-use Bioreactors
10.4.1.1 Products Offered by Players based In North America
10.4.1.2 Products Offered by Players based In Europe
10.4.1.3 Products Offered by Players based In Asia-Pacific and Rest of the World

10.4.2 Fixed-Bed Single-use Bioreactors
10.4.3 Wave-Induced / Rocking Single-use Bioreactors
10.4.4. Other Types of Single-use Bioreactors
10.4.4.1 Products Offered by Players based In North America
10.4.4.2 Products Offered by Players based In Europe
10.4.4.3 Products Offered by Players based In Asia-Pacific and Rest of the World

11. BRAND POSITIONING ANALYSIS 
11.1. Chapter Overview
11.2. Methodology
11.3. Key Parameters
11.4. Brand Positioning Matrix
11.5. Brand Positioning Matrix: Pall Corporation
11.6. Brand Positioning Matrix: Biolinx Labsystems
11.7. Brand Positioning Matrix: Eppendorf
11.8. Brand Positioning Matrix: Solaris Biotech
11.9. Brand Positioning Matrix: Sartorius Stedim Biotech
11.10. Brand Positioning Matrix: Applikon Biotechnology
11.11. Brand Positioning Matrix: Cercell

12. PATENT ANALYSIS 
12.1. Chapter Overview
12.2. Scope and Methodology
12.3. Single-use Bioreactors: Patent Analysis
12.3.1. Analysis by Application Year
12.3.2. Analysis by Publication Year
12.3.3. Analysis by Type of Patents and Publication Year
12.3.4. Analysis by Patent Jurisdiction
12.3.5. Analysis by CPC Symbols
12.3.6. Analysis by Type of Applicant
12.3.7. Leading Industry Players: Analysis by Number of Patents
12.3.8. Leading Patent Assignees: Analysis by Number of Patents

12.4. Single-use Bioreactors: Patent Benchmarking Analysis
12.4.1. Analysis by Patent Characteristics

12.5. Single-use Bioreactors: Patent Valuation
12.6. Leading Patents by Number of Citations

13. MARKET FORECAST AND OPPORTUNITY ANALYSIS
13.1. Chapter Overview
13.2. Key Assumptions and Methodology 
13.3. Global Single-use Upstream Bioprocessing Technology Market, 2023-2035
13.3.1. Global Single-use Upstream Bioprocessing Technology Market: Distribution by Scale of Operation, 2023-2035
13.3.2. Global Single-use Upstream Bioprocessing Technology Market: Distribution by Type of Equipment, 2023-2035
13.3.3. Global Single-use Upstream Bioprocessing Technology Market: Distribution by Geographical Region, 2023-2035

13.4. Global Single-use Bioreactors Market, 2023-2035
13.4.1. Global Single-use Bioreactors Market: Distribution by Type of Bioreactor, 2023-2035
13.4.2. Global Single-use Bioreactors Market: Distribution by Scale of Operation, 2023-2035
13.4.3. Global Single-use Bioreactors Market: Distribution by Type of Cell Culture, 2023-2035
13.4.4. Global Single-use Bioreactors Market: Distribution by Type of Biologics Synthesized, 2023-2035
13.4.5. Global Single-use Bioreactors Market: Distribution by Application Area, 2023-2035
13.4.6. Global Single-use Bioreactors Market: Distribution by End-users, 2023-2035
13.4.7. Global Single-use Bioreactors Market: Distribution by Geographical Region, 2023-2035

14. CASE STUDY: KEY TECHNOLOGICAL INNOVATIONS IN THE SINGLE-USE BIOREACTORS INDUSTRY
14.1. Chapter Overview
14.2. Innovations in Bioreactor Display / Control Features
14.2.1. Built-in System Control Sensors
14.2.2. Advanced Alarm Systems
14.2.3. Electronic-Log Records and Touch Screens
14.2.4. Real-Time Tracking and Remote Monitoring
14.3. Innovation in Mixing Technologies
14.4. Automation in Single-use bioreactors
14.5. Concluding Remarks

15. SWOT ANALYSIS
15.1. Chapter Overview
15.2. Single-use Bioreactors: SWOT Analysis
15.3. Strengths
15.4. Weaknesses
15.5. Opportunities
15.6. Threats
15.7. Comparison of SWOT Factors

16. CASE STUDY: BIOPROCESS CONTROLLERS AND AUTOMATION SYSTEMS
16.1. Chapter Overview
16.2. Bioprocess Control Software: Overall Market Landscape
16.2.1. Analysis by Scale of Operation
16.2.2. Analysis by Key Features
16.2.3. Analysis by Compatibility with System
16.2.4. Analysis by Type of Process Controlled

16.3. Bioprocess Control Software Manufacturers: Overall Market Landscape
16.3.1. Analysis by Year of Establishment
16.3.2. Analysis by Company Size
16.3.3. Analysis by Location of Headquarters

16.4. Upstream Controllers: Overall Market Landscape
16.4.1. Analysis by Scale of Operation
16.4.2. Analysis by Key Features
16.4.3. Analysis by Compatibility with Bioreactor System
16.4.4. Analysis by Type of Bioprocess
16.4.5. Analysis by Type of Process Controlled

16.5. Upstream Controller Manufacturers: Overall Market Landscape
16.5.1. Analysis by Year of Establishment
16.5.2. Analysis by Company Size
16.5.3. Analysis by Location of Headquarters

16.6. Downstream Controller Systems: Overall Market Landscape
16.6.1. Analysis by Scale of Operation
16.6.2. Analysis by Key Features
16.6.3. Analysis by Type of System
16.6.4. Analysis by Type of Bioprocess
16.6.5. Analysis by Application Area

16.7. Downstream Controller System Manufacturers: Overall Market Landscape
16.7.1. Analysis by Year of Establishment
16.7.2. Analysis by Company Size
16.7.3. Analysis by Location of Headquarters

17. CONCLUSION

18. EXECUTIVE INSIGHTS
18.1. Chapter Overview
18.2. Membio
18.2.1. Company Snapshot
18.2.2. Interview Transcript: Shane Kilpatrick, Founder and Chief Executive Officer

18.3. Distek
18.3.1. Company Snapshot
18.3.2. Interview Transcript: Justin Cesmat, Manager, Bioprocessing

18.4. Refine Technology
18.4.1. Company Snapshot
18.4.2. Interview Transcript: Bradley Maykow, Quality and Products Manager

18.5. CerCell
18.5.1. Company Snapshot
18.5.2. Interview Transcript: Per Stobbe, Chief Executive Officer

18.6. CelVivo 
18.6.1. Company Snapshot
18.6.2. Interview Transcript: Torsten Due Bryld, Global Director of Sales Support

19. APPENDIX I: TABULATED DATA

20. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS

21. APPENDIX III: LIST OF BUSINESSES OFFERING BIOPROCESS RELATED ACCESSORIES, EQUIPMENT, AND AUTOMATION SOLUTIONS

List Of Figures

Figure 2.1 Executive Summary: Current Market Landscape of Single-use Bioreactors 
Figure 2.2 Executive Summary: Partnerships and Collaborations
Figure 2.3 Executive Summary: Patent Analysis
Figure 2.4 Executive Summary: Market Forecast and Opportunity Analysis
Figure 3.1 Historical Events related to the Development of Single-use Bioreactors
Figure 3.2 Conventional Stainless-steel Bioreactors and Single-use Bioreactors: Energy Consumption (Mega Joules)
Figure 3.3 Conventional Stainless-steel Bioreactors and Single-use Bioreactors: Water Consumption (Kilo Liters)
Figure 3.4 Single-use Bioreactors: Type of Cell Culture Handled
Figure 3.5 Advantages of Single-use Bioreactors
Figure 3.6 Applications of Single-use Bioreactors
Figure 4.1 Single-use Bioreactors: Distribution by Type of Bioreactor
Figure 4.2 Single-use Bioreactors: Distribution by Scale of Operation
Figure 4.3 Single-use Bioreactors: Distribution by Working Volume (Liters)
Figure 4.4 Single-use Bioreactors: Distribution by Stirrer speed (RPM)
Figure 4.5 Single-use Bioreactors: Distribution by Weight of Bioreactor (Kg)
Figure 4.6 Single-use Bioreactors: Distribution by Advanced Display / Control Features
Figure 4.7 Single-use Bioreactors: Distribution by Mode of Operation 
Figure 4.8 Single-use Bioreactors: Distribution by Type of Culture
Figure 4.9 Single-use Bioreactors: Distribution by Type of Cell Culture
Figure 4.10 Single-use Bioreactors: Distribution by Type of Biologics Synthesized
Figure 4.11 Single-use Bioreactors: Distribution by End-users
Figure 4.12 Single-use Bioreactor Manufacturers: Distribution by Year of Establishment
Figure 4.13 Single-use Bioreactor Manufacturers: Distribution by Company Size
Figure 4.14 Single-use Bioreactor Manufacturers: Distribution by Location of Headquarters (Region)
Figure 4.15 Single-use Bioreactor Manufacturers: Distribution by Location of Headquarters (Country)
Figure 4.16 Leading Manufacturers: Distribution by Number of Products
Figure 5.1 Distribution by Company Size of Manufacturer and Type of Single-use Bioreactor
Figure 5.2 Distribution by Type of Single-use Bioreactor and Mode of Operation
Figure 5.3 Heat Map Representation: Distribution by Type of Single-use Bioreactor and Type of Biologics Synthesized
Figure 5.4 Hybrid Chart: Distribution by Scale of Operation, Type of Cell Culture and Type of Biologics Synthesized
Figure 5.5 Distribution by Company Size and Location of Headquarters
Figure 5.6 World Map Representation: Distribution by Location of Headquarters
Figure 6.1 Company Competitiveness Analysis: Small Companies
Figure 6.2 Company Competitiveness Analysis: Mid-sized Companies
Figure 6.3 Company Competitiveness Analysis: Large Companies
Figure 7.1 Danaher (a parent company of Cytiva): Annual Revenues, 2018 - 2022 (USD Billion)
Figure 7.2 Merck Millipore: Annual Revenues, 2017-2022 (EUR Billion)
Figure 7.3 Danaher (a parent company of Pall Corporation): Annual Revenues, 2018 - 2022 (USD Billion)
Figure 7.4 Thermo Fisher Scientific: Annual Revenues, FY 2017-FY 2022 (USD Billion)
Figure 8.1 Eppendorf: Annual Revenues, FY 2018-FY 2022 (EUR Million)
Figure 8.2 Sartorius Stedim Biotech: Annual Revenues, 2018-Q1 2023 (EUR Million)
Figure 9.1 Partnerships and Collaborations: Cumulative Year-Wise Trend
Figure 9.2 Partnerships and Collaborations: Distribution by Type of Partnership
Figure 9.3 Partnerships and Collaborations: Distribution by Year and Type of Partnership
Figure 9.4 Partnerships and Collaborations: Distribution by Focus Area
Figure 9.5 Partnerships and Collaborations: Distribution by Year of Partnership and Focus Area
Figure 9.6 Partnerships and Collaborations: Distribution by Type of Partner
Figure 9.7 Partnerships and Collaborations: Distribution by Type of Biologics Synthesized
Figure 9.8 Partnerships and Collaborations: Distribution by Type of Bioreactor Involved
Figure 9.9 Partnerships and Collaborations: Distribution by Location of Facility (Country) and Expanded Bioreactor Capacity
Figure 9.10 Most Active Players: Distribution by Number of Partnerships
Figure 9.11 Partnerships and Collaborations: Local and International Agreements
Figure 9.12 Partnerships and Collaborations: Intracontinental and Intercontinental Agreements
Figure 10.1 Product Competitiveness Analysis: Stirred Tank Single-use Bioreactors Offered by Players in North America
Figure 10.2 Product Competitiveness Analysis: Stirred Tank Single-use Bioreactors Offered by Players in Europe
Figure 10.3 Product Competitiveness Analysis: Stirred Tank Single-use Bioreactors Offered by Players in Asia-Pacific and Rest of the World
Figure 10.4 Product Competitiveness Analysis: Fixed-Bed Single-use Bioreactors
Figure 10.5 Product Competitiveness Analysis: Wave-Induced / Rocking Single-use Bioreactors
Figure 10.6 Product Competitiveness Analysis: Other Types of Single-use Bioreactors Offered by Players in North America
Figure 10.7 Product Competitiveness Analysis: Other Types of Single-use Bioreactors Offered by Players in Europe
Figure 10.8 Product Competitiveness Analysis: Other Types of Single-use Bioreactors Offered by Players in Asia-Pacific and Rest of the World
Figure 11.1 Brand Positioning Analysis: Competitive Advantage
Figure 11.2 Brand Positioning Analysis: Reasons to Believe
Figure 11.3 Brand Positioning Matrix: Pall Corporation
Figure 11.4 Brand Positioning Matrix: Biolinx Labsystems
Figure 11.5 Brand Positioning Matrix: Eppendorf
Figure 11.6 Brand Positioning Matrix: Solaris Biotech
Figure 11.7 Brand Positioning Matrix: Sartorius Stedim Biotech
Figure 11.8 Brand Positioning Matrix: Applikon Biotechnology
Figure 11.9 Brand Positioning Matrix: Cercell
Figure 12.1 Patent Analysis: Distribution by Type of Patent
Figure 12.2 Patent Analysis: Cumulative Year-wise Trend by Application Year, Pre-2015–2023
Figure 12.3 Patent Analysis: Cumulative Year-wise Trend by Publication Year, Pre-2015–2023
Figure 12.4 Patent Analysis: Distribution of Type of Patents and Publication Year, Pre-2015-2023
Figure 12.5 Patent Analysis: Distribution by Patent Jurisdiction
Figure 12.6 Patent Analysis: Distribution by CPC Symbols and Sections
Figure 12.7 Patent Analysis: Cumulative Year-wise Distribution by Type of Applicant
Figure 12.8 Leading Industry Players: Distribution by Number of Patents
Figure 12.9 Leading Patent Assignees: Distribution by Number of Patents
Figure 12.10 Patent Benchmarking Analysis: Distribution of Top Nine Industry Players by CPC Codes
Figure 12.11 Patent Analysis: Distribution by Patent Age
Figure 12.12 Single-use Bioreactors: Patent Valuation
Figure 13.1 Global Single-use Upstream Bioprocessing Technology Market, 2023-2035 (USD Billion)
Figure 13.2 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Scale of Operation, 2023-2035 (USD Billion)
Figure 13.3 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Type of Equipment, 2023-2035 (USD Billion)
Figure 13.4 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Geographical Region, 2023-2035 (USD Billion)
Figure 13.5 Global Single-use Bioreactors Market, 2023-2035 (USD Billion)
Figure 13.6 Global Single-use Bioreactors Market: Distribution by Type of Bioreactor, 2023-2035 (USD Billion)
Figure 13.7 Global Single-use Bioreactors Market: Distribution by Scale of Operation, 2023-2035 (USD Billion)
Figure 13.8 Global Single-use Bioreactors Market: Distribution by Type of Cell Culture, 2023-2035 (USD Billion)
Figure 13.9 Global Single-use Bioreactors Market: Distribution by Type of Biologics Synthesized, 2023-2035 (USD Billion)
Figure 13.10 Global single-use Bioreactors Market: Distribution by Application Area, 2023-2035 (USD Billion)
Figure 13.11 Global single-use Bioreactors Market: Distribution by End-users, 2023-2035 (USD Billion)
Figure 13.12 Global Single-use Bioreactors Market: Distribution by Geographical Region, 2023-2035 (USD Billion)
Figure 14.1 Single-use Bioreactors Market: SWOT Analysis
Figure 14.2 Comparison of SWOT Factors: Harvey Ball Analysis
Figure 16.1 Bioprocess Control Software: Distribution by Scale of Operation
Figure 16.2 Bioprocess Control Software: Distribution by Key Features
Figure 16.3 Bioprocess Control Software: Distribution by Compatibility with System
Figure 16.4 Bioprocess Control Software: Distribution by Type of Process Controlled
Figure 16.5 Bioprocess Control Software Manufacturers: Distribution by Year of Establishment
Figure 16.6 Bioprocess Control Software Manufacturers: Distribution by Company Size
Figure 16.7 Bioprocess Control Software Manufacturers: Distribution by Location of Headquarters
Figure 16.8 Upstream Controllers: Distribution by Scale of Operation
Figure 16.9 Upstream Controllers: Distribution by Key Features
Figure 16.10 Upstream Controllers: Distribution by Compatibility with Bioreactor systems
Figure 16.11 Upstream Controllers: Distribution by Type of Bioprocess
Figure 16.12 Upstream Controllers: Distribution by Type of Process Controlled
Figure 16.13 Upstream Controller Manufacturers: Distribution by Year of Establishment
Figure 16.14 Upstream Controller Manufacturers: Distribution by Company Size
Figure 16.15 Upstream Controller Manufacturers: Distribution by Location of Headquarters
Figure 16.16 Downstream Controller Systems: Distribution by Scale of Operation
Figure 16.17 Downstream Controller Systems: Distribution by Key Features
Figure 16.18 Downstream Controller Systems: Distribution by Type of System
Figure 16.19 Downstream Controller Systems: Distribution by Type of Bioprocess
Figure 16.20 Downstream Controller Systems: Distribution by Application Area
Figure 16.21 Downstream Controller System Manufacturers: Distribution by Year of Establishment
Figure 16.22 Downstream Controller System Manufacturers: Distribution by Company Size
Figure 16.23 Downstream Controller System Manufacturers: Distribution by Location of Headquarters
Figure 17.1 Concluding Remarks: Current Market Landscape of Single-use Bioreactors
Figure 17.2 Concluding Remarks: Partnerships and Collaborations
Figure 17.3 Concluding Remarks: Patent Analysis
Figure 17.4 Concluding Remarks: Market Forecast and Opportunity Analysis

List Of Table

Table 3.1 Comparison between Conventional and Single-use Bioreactors
Table 4.1 Single-use Bioreactors: Information on Manufacturer, Status of Development, Type of Bioreactor and Scale of Operation
Table 4.2 Single-use Bioreactors: Information on Working Volume, Stirrer Speed, Weight and Dimensions of Bioreactor
Table 4.3 Single-use Bioreactors: Information on Advanced Display / Control Features
Table 4.4 Single-use Bioreactors: Information on Mode of Operation
Table 4.5 Single-use Bioreactors: Information on Type of Culture and Type of Cell Culture
Table 4.6 Single-use Bioreactors: Information on Type of Biologics Synthesized
Table 4.7 Single-use Bioreactors: Information on End-users
Table 4.8 Single-use Bioreactors: List of Manufacturers
Table 7.1 Single-use Bioreactors: List of Companies Profiled
Table 7.2 Celartia: Company Snapshot
Table 7.3 Celartia: Product Portfolio
Table 7.4 Cell Culture Company: Company Snapshot
Table 7.5 Cell Culture Company: Product Portfolio
Table 7.6 Cytiva: Company Snapshot
Table 7.7 Cytiva: Product Portfolio
Table 7.8 Merck Millipore: Company Snapshot
Table 7.9 Merck Millipore: Product Portfolio
Table 7.10 Merck Millipore: Recent Developments and Future Outlook
Table 7.11 Pall Corporation: Company Snapshot
Table 7.12 Pall Corporation: Product Portfolio
Table 7.13 Pall Corporation: Recent Developments and Future Outlook
Table 7.14 PBS Biotech: Company Snapshot
Table 7.15 PBS Biotech: Product Portfolio
Table 7.16 PBS Biotech: Recent Developments and Future Outlook
Table 7.17 Synthecon: Company Snapshot
Table 7.18 Synthecon: Product Portfolio
Table 7.19 Thermo Fisher Scientific: Company Snapshot
Table 7.20 Thermo Fisher Scientific: Product Portfolio
Table 7.21 Thermo Fisher Scientific: Recent Developments and Future Outlook
Table 8.1 Single-use Bioreactors: List of Companies Profiled
Table 8.2 Applikon Biotechnology: Company Snapshot
Table 8.3 Applikon Biotechnology: Product Portfolio
Table 8.4 Applikon Biotechnology: Recent Developments and Future Outlook
Table 8.5 Cellexus: Company Snapshot
Table 8.6 Cellexus: Product Portfolio
Table 8.7 Cellexus: Recent Developments and Future Outlook
Table 8.8 CerCell: Company Snapshot
Table 8.9 CerCell: Product Portfolio
Table 8.10 CerCell: Recent Developments and Future Outlook
Table 8.11 Eppendorf: Company Snapshot
Table 8.12 Eppendorf: Product Portfolio
Table 8.13 Eppendorf: Recent Developments and Future Outlook
Table 8.14 PerfuseCell: Company Snapshot
Table 8.15 PerfuseCell: Product Portfolio
Table 8.16 PerfuseCell: Recent Developments and Future Outlook
Table 8.17 ProlifeCell: Company Snapshot
Table 8.18 ProlifeCell: Product Portfolio
Table 8.19 ProlifeCell: Recent Developments and Future Outlook
Table 8.20 Sartorius Stedim Biotech: Company Snapshot
Table 8.21 Sartorius Stedim Biotech: Product Portfolio
Table 8.22 Sartorius Stedim Biotech: Recent Developments and Future Outlook
Table 8.21 Solaris Biotech: Company Snapshot
Table 8.22 Solaris Biotech: Product Portfolio
Table 8.23 Solaris Biotech: Recent Developments and Future Outlook
Table 8.24 Biolinx Labsystems: Company Snapshot
Table 8.25 Biolinx Labsystems: Product Portfolio
Table 8.26 CESCO Bioengineering: Company Snapshot
Table 8.27 CESCO Bioengineering: Product Portfolio
Table 9.1 Single-use Bioreactors: List of Partnerships and Collaborations
Table 9.2 Single-use Bioreactors: Information on Location of Partner (Country and Continent)
Table 10.1 Product Competitiveness Analysis: Information on Peer Groups
Table 12.1 Patent Analysis: Top CPC Sections
Table 12.2 Patent Analysis: Top CPC Symbols
Table 12.3 Patent Analysis: Top CPC Codes
Table 12.4 Patent Analysis: Summary of Benchmarking Analysis
Table 12.5 Patent Analysis: Categorization based on Weighted Valuation Scores
Table 12.6 Patent Analysis: List of Leading Patents (by Number of Citations)
Table 16.1 Bioprocess Control Software: Information on Stage of Bioprocess and Scale of Operation
Table 16.2 Bioprocess Control Software: Information on Key Features, Compatibility with Bioreactor Systems and Processes Controlled
Table 16.3 Bioprocess Control Software Manufacturers: Information of Year of Establishment, Company Size and Location of Headquarters
Table 16.4 Upstream Controllers: Information on Dimensions and Scale of Operation
Table 16.5 Upstream Controllers: Information on Key Features, Type of Bioprocess and Compatibility with Bioreactor Systems, and Processes Controlled
Table 16.6 Upstream Controller Manufacturers: Information on Year of Establishment, Company Size and Location of Headquarters
Table 16.7 Downstream Controller Systems: Information on Dimensions, Type of Controllers and Scale of Operation
Table 16.8 Downstream Controller Systems: Information on Key Features, Type of System, Type of Bioprocess and Application Areas
Table 16.9 Downstream Controller System Manufacturers: Information of Year of Establishment, Company Size and Location of Headquarters
Table 18.1 Membio: Company Snapshot
Table 18.2 Distek: Company Snapshot
Table 18.3 Refine Technology: Company Snapshot
Table 18.4 CerCell: Company Snapshot
Table 18.5 CelVivo: Company Snapshot
Table 19.1 Conventional Stainless-steel Bioreactors and Single-use Bioreactors: Energy Consumption (Mega Joules)
Table 19.2 Conventional Stainless-steel Bioreactors and Single-use Bioreactors: Water Consumption (Kilo Liters)
Table 19.3 Single-use Bioreactors: Distribution by Type of Bioreactor
Table 19.4 Single-use Bioreactors: Distribution by Scale of Operation
Table 19.5 Single-use Bioreactors: Distribution by Working Volume 
Table 19.6 Single-use Bioreactors: Distribution by Stirrer speed
Table 19.7 Single-use Bioreactors: Distribution by Weight of Bioreactor
Table 19.8 Single-use Bioreactors: Distribution by Advanced Display / Control Features
Table 19.9 Single-use Bioreactors: Distribution by Mode of Operation 
Table 19.10 Single-use Bioreactors: Distribution by Type of Culture
Table 19.11 Single-use Bioreactors: Distribution by Type of Cell Culture
Table 19.12 Single-use Bioreactors: Distribution by Type of Biologics Synthesized
Table 19.13 Single-use Bioreactors: Distribution by End-users
Table 19.14 Single-use Bioreactor Manufacturers: Distribution by Year of Establishment
Table 19.15 Single-use Bioreactor Manufacturers: Distribution by Company Size
Table 19.16 Single-use Bioreactor Manufacturers: Distribution by Location of Headquarters (Region)
Table 19.17 Single-use Bioreactor Manufacturers: Distribution by Location of Headquarters (Country)
Table 19.18 Leading Manufacturers: Distribution by Number of Products
Table 19.19 Distribution by Company Size of manufacturer and Type of Single-use Bioreactor
Table 19.20 Distribution by Type of Single-use Bioreactor and Mode of Operation
Table 19.21 Distribution by Company Size and Location of Headquarters
Table 19.22 World Map Representation: Distribution by Location of Headquarters
Table 19.23 Danaher (a parent company of Cytiva): Annual Revenues, 2018 - 2022 (USD Billion)
Table 19.24 Merck Millipore: Annual Revenues, 2017-2022 (EUR Billion)
Table 19.25 Danaher (a parent company of Pall Corporation): Annual Revenues, 2018 - 2022 (USD Billion)
Table 19.26 Thermo Fisher Scientific: Annual Revenues, 2017-2022 (USD Billion)
Table 19.27 Eppendorf: Annual Revenues, 2018-2022 (EUR Million)
Table 19.28 Sartorius Stedim Biotech: Annual Revenues, 2018-Q1 2023 (EUR Million)
Table 19.29 Partnerships and Collaborations: Cumulative Year-Wise Trend
Table 19.30 Partnerships and Collaborations: Distribution by Type of Partnership
Table 19.31 Partnerships and Collaborations: Distribution by Year and Type of Partnership
Table 19.32 Partnerships and Collaborations: Distribution by Focus Area
Table 19.33 Partnerships and Collaborations: Distribution by Year of Partnership and Focus Area
Table 19.34 Partnerships and Collaborations: Distribution by Type of Partner
Table 19.35 Partnerships and Collaborations: Distribution by Type of Biologics Synthesized
Table 19.36 Partnerships and Collaborations: Distribution by Type of Bioreactor Involved
Table 19.37 Most Active Players: Distribution by Number of Partnerships
Table 19.38 Partnerships and Collaborations: Local and International Agreements
Table 19.39 Partnerships and Collaborations: Intracontinental and Intercontinental Agreements
Table 19.40 Patent Analysis: Distribution by Type of Patent
Table 19.41 Patent Analysis: Cumulative Year-wise Trend by Application Year, Pre-2015–2023
Table 19.42 Patent Analysis: Cumulative Year-wise Trend by Publication Year, Pre-2015–2023
Table 19.43 Patent Analysis: Distribution of Type of Patents and Publication Year, Pre-2015-2023
Table 19.44 Patent Analysis: Distribution by Patent Jurisdiction
Table 19.45 Patent Analysis: Cumulative Year-wise Distribution by Type of Applicant
Table 19.46 Leading Industry Players: Distribution by Number of Patents
Table 19.47 Leading Patent Assignees: Distribution by Number of Patents
Table 19.48 Patent Analysis: Distribution by Patent Age
Table 19.49 Single-use Bioreactors: Patent Valuation
Table 19.50 Global Single-use Upstream Bioprocessing Technology Market, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.51 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Scale of Operation, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.52 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Type of Equipment, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.53 Global Single-use Upstream Bioprocessing Technology Market: Distribution by Geographical Region, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.54 Global Single-use Bioreactor Market, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.55 Global Single-use Bioreactor Market: Distribution by Type of Bioreactor, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.56 Global Single-use Bioreactor Market: Distribution by Scale of Operation, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.57 Global Single-use Bioreactor Market: Distribution by Type of Cell Culture, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.58 Global Single-use Bioreactor Market: Distribution by Type of Biologics Synthesized, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.59 Global single-use Bioreactor Market: Distribution by Application Area, Conservative, Base and Optimistic Scenario,2023-2035 (USD Billion)
Table 19.60 Global single-use Bioreactor Market: Distribution by End-users, Conservative, Base and Optimistic Scenario,2023-2035 (USD Billion)
Table 19.61 Global Single-use Bioreactor Market: Distribution by Geographical Region, Conservative, Base and Optimistic Scenario, 2023-2035 (USD Billion)
Table 19.62 Bioprocess Control Software: Distribution by Scale of Operation
Table 19.63 Bioprocess Control Software: Distribution by Key Features
Table 19.64 Bioprocess Control Software: Distribution by Compatibility with Systems
Table 19.65 Bioprocess Control Software: Distribution by Type of Process Controlled
Table 19.66 Bioprocess Control Software Manufacturers: Distribution by Year of Establishment
Table 19.67 Bioprocess Control Software Manufacturers: Distribution by Company Size
Table 19.68 Bioprocess Control Software Manufacturers: Distribution by Location of Headquarters
Table 19.69 Upstream Controllers: Distribution by Scale of Operation
Table 19.70 Upstream Controllers: Distribution by Key Features
Table 19.71 Upstream Controllers: Distribution by Compatibility with Bioreactor systems
Table 19.72 Upstream Controllers: Distribution by Type of Bioprocess
Table 19.73 Upstream Controllers: Distribution by Type of Process Controlled
Table 19.74 Upstream Controller Manufacturers: Distribution by Year of Establishment
Table 19.75 Upstream Controller Manufacturers: Distribution by Company Size
Table 19.76 Upstream Controller Manufacturers: Distribution by Location of Headquarters
Table 19.77 Downstream Controller Systems: Distribution by Scale of Operation
Table 19.78 Downstream Controller Systems: Distribution by Key Features
Table 19.79 Downstream Controller Systems: Distribution by Type of System
Table 19.80 Downstream Controller Systems: Distribution by Type of Bioprocess
Table 19.81 Downstream Controller Systems: Distribution by Application Area
Table 19.82 Downstream Controller System Manufacturers: Distribution by Year of Establishment
Table 19.83 Downstream Controller System Manufacturers: Distribution by Company Size
Table 19.84 Downstream Controller System Manufacturers: Distribution by Location of Headquarters

List Of Companies

  1. ABEC
  2. Abertay University
  3. ABL Europe
  4. Abzena
  5. Advanced Process Systems
  6. Advanced Scientifics
  7. Aetos Biologics
  8. Agilitech
  9. Applikon Biotechnology
  10. Artelis
  11. ARTeSYN BioSolutions
  12. ATMI LifeSciences (acquired by Pall Corporation)
  13. AUCTEQ Biosystems
  14. The Base Facility (a part of The University of Queensland)
  15. Bayer Technology Services
  16. bbi-biotech
  17. BioInno Bioscience 
  18. BioInvent International
  19. Biolinx Labsystems
  20. Bionet 
  21. BioReactor Sciences
  22. Bioreactors.net
  23. Biosan
  24. Biotechnologies Inc.
  25. BioVectra
  26. BlueSens
  27. Brammer Bio
  28. Catalent
  29. CB Technology
  30. CCRM
  31. Celartia
  32. Cell Culture Company 
  33. Cellexus
  34. Celltainer Biotech
  35. CelVivo
  36. CerCell
  37. CESCO Bioengineering
  38. Cobra Biologics
  39. Corning
  40. CSL
  41. Cytiva
  42. Dakewe Biotech
  43. Danaher
  44. Distek
  45. Doga
  46. Donaldson
  47. Electrolab Biotech
  48. EMD Millipore
  49. Emergent BioSolutions
  50. Emerson
  51. Entegris 
  52. Eppendorf
  53. Erbi Biosystems
  54. Esco Aster
  55. ExcellGene
  56. Exothera
  57. Finesse Solutions
  58. Flotek
  59. Freeline
  60. G&G Technologies
  61. GE Healthcare
  62. Getinge 
  63. GPC Bio
  64. Green Cross Medical Science
  65. Hamilton
  66. Hegewald Medizinprodukte
  67. Henan Lanphan
  68. ILS Automation
  69. Industrial Biotechnology Innovation Centre (IBioIC)
  70. INFORS HT
  71. INTEGRA Biosciences
  72. Integrity CMI (acquired by PBS Biotech)
  73. Kuhner shaker
  74. LAMBDA Laboratory Instruments
  75. LePure Biotech
  76. LevTech (acquired by ATMI)
  77. LFB Biomanufacturing
  78. Lonza
  79. Mabion
  80. mAbxience
  81. Membio 
  82. Merck Millipore
  83. MicroDigital 
  84. New Brunswick Scientific
  85. New Horizon Biotech
  86. Nova Biomedical
  87. Ology Bioservices
  88. OmniBRx Biotechnologies
  89. Pall Corporation
  90. PAN-Biotech
  91. PBS Biotech
  92. PendoTECH
  93. Penn State University
  94. PerfuseCell
  95. Pierre Guérin
  96. Precision Biologics
  97. Precision Technologies 
  98. Premas Biotech
  99. Progenitor Cell Therapy
  100. ProlifeCell
  101. Prometheus
  102. Protalix BioTherapeutics
  103. RealBio Technology
  104. Refine Technology
  105. Rentschler Biopharma
  106. Repligen
  107. ReproCell
  108. Roch Mechatronics
  109. RoosterBio
  110. Rosemount
  111. Rotech Bioengineering
  112. Sartorius Stedim Biotech
  113. SATAKE MultiMix
  114. Scinus Cell Expansion
  115. SCRUM
  116. Sepragen
  117. Serum Institute of India
  118. Siemens Technology
  119. Solaris Biotech
  120. Solida Biotech
  121. State Key Laboratory of Experimental Hematology
  122. STEMCELL Technologies
  123. Südpack Medica
  124. Synthecon
  125. Sysbiotech
  126. System-C Bioprocess (a part of Fortil Group)
  127. T&J Bioengineering
  128. TECNIC 
  129. Texas Tech Health Science Center
  130. University of Alberta
  131. Brescia University
  132. The University of Milan
  133. The University of Zurich
  134. Thermo Fisher Scientific
  135. Triumvirate Environmental
  136. Univercells 
  137. Verder 
  138. VERDOT Ips
  139. Viaflo 
  140. Wake Forest Intstitute for Regenerative Medicine
  141. Waters
  142. Wave Biotech
  143. Wuhan Bio-Raid Biotechnology
  144. WUHAN CEKG TECH
  145. WuXi Biologics
  146. Xcellerex
  147. Zhejiang JYSS Bio-Engineering

Source 1: https://www.scienceboard.net/index.aspx?sec=sup&sub=cell&pag=dis&ItemID=803
Source 2: https://www.nature.com/articles/s41587-022-01630-6

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