Top Fill Finish Manufacturing Companies
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Published: January 2025
Given the requirement of specialized and precise processes (such as aseptic filling lines), stringent regulatory compliances, and well-established equipment, infrastructure, and personnel (associated with high capital investments), there is an increased reliance on small molecules fill finish CMOs from drug developers; consequently, driving the growth of fill finish pharmaceutical contract manufacturing market.We analyzed over 390 fill finish manufacturing companies that are engaged in offering fill finish services. In this article, discover five top companies and their capabilities in fill finish pharmaceutical contract manufacturing market.
Fill finish is the final step in downstream processing of a product, wherein the purified formulation of the small molecules is mixed with the necessary excipients and stabilizers. The product is then formulated and aliquoted into the appropriate dosage forms for clinical use or commercial distribution. These operations are automated and are usually carried out under aseptic conditions. Unit operations involved in the fill finish process include compounding and mixing, filling, lyophilization, closing, sealing, sorting, inspection, labeling and packaging of the product. Given the requirement of specialized and precise processes (such as aseptic filling lines), stringent regulatory compliances, and well-established equipment, infrastructure, and personnel (associated with high capital investments), there is an increased reliance on small molecules fill finish CMOs from drug developers; consequently, driving the growth of pharmaceutical fill finish market.
The growing pipeline of novel small molecule drugs has necessitated the drug developers to have flexible production scale. Also, companies are investing in highly automated aseptic filling machine with robotic systems to reduce manual interventions and improve efficiency of fill finish processes.
Roots Analysis has conducted an exhaustive study on Fill Finish Pharmaceutical Contract Manufacturing Market featuring the current market landscape and future opportunity for the companies engaged in offering fill finish services, over a span of 11 years.
Table of Contents
Below, we have listed (in alphabetical order), the top five fill finish manufacturing companies:
- Alcami
- Aurigene Pharmaceutical Services
- Eriochem
- Fresenius Kabi
- Sharp Services
Interested in exploring all 390+ Fill Finish Pharmaceutical Contract Manufacturing Companies and their recent initiatives?
Discover Below the Details on Five Top Fill Finish Manufacturing Companies
Let us deep dive to understand the activity of the five top fill finish manufacturing companies (companies offering more than one type of fill finish service) in the fill finish pharmaceutical contract manufacturing market. It is essential to note that the selection of top players can differ substantially according to the defined criteria.
Alcami, has Been Acquiring and Expanding to Strengthen its Service Offering
1. Alcami
Alcami is a US-based firm offering services to support the formulation development, analytical testing, manufacturing and packaging of biologics and small molecule therapies. Since 1985, the firm has contributed to the launch of more than 50 products and filing of over 500 Investigational New Drug (IND) applications. Through its state-of-the-art facilities in the US and Europe, it claims to have supported the projects of various pharmaceutical and biopharmaceutical companies, in more than 35 countries.
In January 2024, the company announced the acquisition of Pacific Pharmaceutical Services to further strengthen its service offerings from full drug product development to manufacturing of both sterile fill finish and oral solid dose.
Alcami: Company Overview
|
Key Parameters |
Description |
| Company Logo |  |
| Year of Establishment | 1979 |
| Number of Employees | 501-1,000 |
| Headquarters | US |
The company is anticipated to focus on additions to support a wide variety of research and early-phase development activities. In March 2022, the company announced the addition of 3,800 ft² non-GMP Formulation Development Laboratory (FDL) within its existing facility offering four isolator filling lines for both liquid and lyophilized products. In a recent expansion in February 2024 at the Charleston, South Carolina facility added another aseptic filling line for liquid and freeze-dried vials.
Further details on recent initiatives taken by Alcami and other fill finish manufacturing companies have been provided in detail in the report.
Aurigene is Expanding its Presence in the Asia-Pacific, to Serve the Growing Market in the Region
2. Aurigene Pharmaceutical Services
Aurigene Pharmaceutical Services is a fully integrated contract development and manufacturing organization, provides end-to-end solutions for development and cGMP manufacturing of both small and large molecules across sites in the US, the UK, Mexico and India. In addition, the firm offers a broad range of formulation development services for various dosage forms, such as oral solids, liquids, injectables, being developed across different scales of operation.
Aurigene Pharmaceutical Services: Company Details
|
Particulars |
Specifications |
| Company Logo |  |
| Year of Establishment | 2002 |
| Number of Employees | 501-1,000 |
| Headquarters | India |
In May 2023, the company announced its plans for an investment of USD 40 million on a new production facility in Hyderabad, India, where a fill finish line is also under construction.
In the coming years, the firm is likely to appoint other eminent personalities to its management team in order to augment its leadership to pave the way for future development. In November 2023, Aurigene Pharmaceutical Services appointed Roger Lias as the Chief Commercial Officer.
Further details on recent initiatives taken by Aurigene Pharmaceutical Services and other fill finish manufacturing companies have been provided in detail in the report.
Eriochem Has a Strong Focus on Vertical Integration, With Both API and Finished Product Manufacturing Approved by Various Regulatory Authorities
3. Eriochem
Eriochem is a pharmaceutical company focused on the synthesis of Active Pharmaceutical Ingredients (API), finished pharmaceutical products in the field of oncology, and the development of added value generics or super-generics. It is worth mentioning that both API and the processing of finished products are certified by a number of authorities, including European Medicines Agency (EMA) and United States Food and Drug Administration (USFDA).
Eriochem: Company Overview
|
Particulars |
Specifications |
| Company Logo |  |
| Year of Establishment | 2000 |
| Number of Employees | 201-500 |
| Headquarters | Argentina |
The company aims for the registration and marketing of drug products registered in the US, with the establishment of its new subsidiary, ERIOCHEM USA, which is headquartered in Nevada.
Further details on recent initiatives taken by Eriochem and other fill finish manufacturing companies have been provided in detail in the report.
In FY 2023, Fresenius Reported Revenues Worth EUR 22.3 Bn, an Increase of 4% From the Revenues Reported During the Same Period in the Last Year
4. Fresenius Kabi
Fresenius Kabi is a healthcare company that is focused on offering customized contract development and manufacturing services to its global pharmaceutical and biopharmaceutical client base. The firm caters to the needs of drug development and manufacturing by providing an array of services from early process development to commercial-scale production of finished drug products. The company operates through two business segments, namely sterile pharmaceuticals and medical devices. Through its sterile pharmaceutical division, the firm offers aseptic filling, labeling and packaging services for a wide range of sterile drugs.
Fresenius Kabi: Company Overview
|
Particulars |
Specifications |
| Company Logo |  |
| Year of Establishment | 1999 |
| Number of Employees | 10,001+ |
| Headquarters | Germany |
The firm is expected to make similar appointments to its senior management team to onboard individuals who have the required qualifications and experience to see the company through its upcoming phases of growth. In June 2024, Fresenius Kabi appointed Sang-Jin Pak as the President for its Biopharma business segment.
Further details on recent initiatives taken by Fresenius Kabi and other fill finish manufacturing companies have been provided in detail in the report.
In May 2024, Sharp Services Announced the Establishment of a New Facility at Pennsylvania, US in order to Increase its Production Capacity for Sterile Injectables Secondary Packaging
5. Sharp Services
Sharp Services is a pharmaceutical company that offers a broad range of services, including formulation development, manufacturing and packaging of biologics and small molecules along with the expertise in clinical trial supply services. CDMO business is involved in sterile injectable contract manufacturing. According to the company’s website, they have eight facilities in the US and Europe to offer comprehensive support to their clients throughout the entire product lifecycle, from early-stage clinical trials to the commercial launch of its products.
Sharp Services: Company Overview
|
Particulars |
Specifications |
| Company Logo |  |
| Year of Establishment | 1993 |
| Number of Employees | 1,001-5,000 |
| Headquarters | US |
In October 2023, Sharp Services acquired Berkshire Sterile Manufacturing to further strengthen its service offerings, including sterile drug product manufacturing, clinical trial services, commercial packaging, and distribution.
Further details on recent initiatives taken by Sharp Services and other fill finish manufacturing companies have been provided in detail in the report.
What About the Other Fill Finish Manufacturing Companies Around the World?
The above presentation features five top fill finish manufacturing companies selected from a pool of over 65 players that we have compiled. If you're interested, you can download the Sample Report on this topic by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com
Sources
- https://www.alcami.com/blog/alcami-announces-acquisition-of-west-coast-based-pacific-pharmaceutical-services
- https://www.alcami.com/blog/gho-capital-and-the-vistria-group-complete-acquisition-of-leading-cdmo-alcami-corporation
- https://www.alcami.com/news/cdmo-alcami-expands-fill-finish-manufacturing-capacity-with-new-charleston-line/
- https://www.fresenius-kabi.com/content/dam/fresenius-kabi/global/documents/press-releases/20230525_FSE_Press_Release_CMD_2023.pdf.coredownload.inline.pdf
- https://www.linkedin.com/in/sang-jin-dr-pak-65516817/?originalSubdomain=kr
- https://www.sharpservices.com/about-us/news/sharp-services-announces-expansion-in-pennsylvania-to-facilitate-growth-in-sterile-injectable-market/
- https://www.sharpservices.com/about-us/news/sharp-acquires-berkshire-sterile-manufacturing/