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The high energy / hazardous chemistry market is estimated to be worth $14 billion in 2020 and is expected to grow at CAGR of 8% during the forecast period. In pharmaceutical manufacturing, the use of certain hazardous chemical reactions has been shown to enable developers to optimize existing production processes, as well as improve yields. In other words, certain chemical reactions, which are generally regarded as harmful, offer a more direct route to the end product, requiring fewer raw materials and involving a limited number of side reactions. As a result, the number of process steps are essentially reduced, when compared to using conventional synthesis chemistries. Prominent examples of hazardous chemical reactions include nitrations, oxidations, hydrogenations, alkylations, and reactions involving unstable or highly active compounds (such as azides, nitrate esters, peroxides, diazo compounds and highly potent substances). Generally, such reactions are carried out under specialized temperature and pressure conditions. However, they are usually not considered during the early drug development stages, owing to the associated risks. From a large-scale manufacturing perspective, the use of such techniques has been proven to offer substantial time and cost-related benefits. In this context, it is also worth mentioning that using hazardous synthesis chemistries it is possible to design new chemical structures, which have interesting bio-active properties, and offer the means to improve overall product quality. Owing to this, the high energy / hazardous chemistry market is likely to witness substantial market growth during the forecast period.
Examples of key companies engaged in high energy / hazardous chemistry market (which have also been profiled in this market report; the complete list of companies is available in the full report) include AGC Chemicals, Beijing Mediking Biopharm, Cambrex, Corden Pharma, Evonik, Hovione, Patheon, PCI Synthesis and Siegfried. This market report includes an easily searchable excel database of all the companies providing high energy chemistry based contract manufacturing, worldwide.
Given the inherent risks associated with hazardous chemistry-based manufacturing processes, innovator companies (especially in the fine chemicals and pharmaceutical industries) prefer to outsource such processes to contract service providers. Presently, there are a number of contract chemicals manufacturers that claim to have the necessary capabilities and infrastructure to support the synthesis of APIs under hazardous conditions. It is worth highlighting that such reactions are best contained within continuous flow processes. However, owning to various reasons (such as reaction specific complexities, fluctuating volumes and certain application specific requirements) the fine chemicals and pharmaceutical industries tend to rely on the traditional batch process. However, there is an evident shift in operating preferences to continuous systems, which is anticipated to bring about revolutionary changes in the long term. Considering the growing global population and the rising demand for new and effective drugs, faster and more efficient pharmaceutical manufacturing processes have become a necessity. In fact, if a drug against COVID-19 is successfully developed, it is imperative to develop high efficiency processes to ensure the production of sufficient volumes of the therapeutic to treat the global population. We are led to believe that the use of high energy chemistry and hazardous chemistries have much to offer in the aforementioned context. As a consequence, the contract services market catering to this segment of the pharmaceutical industry is anticipated to witness substantial market growth in the coming years.
The ‘High Energy / Hazardous Chemistry Market: Focus on High Temperature, Low Temperature / Cryogenic, High Pressure and Low Pressure Chemistries, 2020-2030’ market report features an extensive study on the current market landscape, market size, market share, market growth, market forecast, market outlook and future opportunities of the high energy / hazardous chemistry market. The market research report features an in-depth analysis, highlighting the capabilities of a diverse set of industry stakeholders.
Amongst other elements, the market research report features:
The key objective of high energy / hazardous chemistry market report is to provide a detailed market analysis in order to estimate the existing market size, market trends, market value, statistics and future opportunity for high energy / hazardous chemistry market during the forecast period. Based on multiple parameters, such as growth of the overall pharmaceutical drugs market, cost of goods sold, direct manufacturing costs and API manufacturing market, we have developed informed estimates on the financial evolution of the market, over the forecast period 2020-2030. The market report also provides details on the likely distribution of the current and forecasted opportunity across [A] reaction conditions (low temperature, high temperature, low pressure, high pressure), [B] company size (small, mid-sized, large / very large) and [C] region (North America, Europe and Asia Pacific) and [D] scale of operation (preclinical / clinical, commercial). In order to account for future uncertainties and to add robustness to our forecast model, we have provided three market forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry’s growth.
The opinions and insights presented in this market research were also influenced by discussions conducted with stakeholders in high energy / hazardous chemistry market. All actual figures have been sourced and analyzed from publicly available information forums. Financial figures mentioned in this market report are in USD, unless otherwise specified.