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CAR-T Cell Therapies Market (3rd Edition) by Target Indications (NHL, Multiple Myeloma, Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Hepatocellular Carcinoma and Others), Target Antigens (CD19, BCMA, CD19 / CD22, GPC3 and EGFR), Key Players and Key Geographies (North America, Europe, Asia Pacific, Latin America, Middle East and North Africa, and Rest of the World) – Industry Trends and Global Forecasts, 2021-2030

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    March 2021

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Example Insights

CAR-T-Therapies-Market-Context CAR-T-Therapies-Market-Trends-on-Twitter CAR-T-Therapies-Market-Development-Pipeline CAR-T-Therapies-Market-Distribution-by-Indication
CAR-T-Therapies-Market-Distribution-by-Geography CAR-T-Therapies-Market-Mapping-Key-Opinion-Leaders CAR-T-Therapies-Market-Industry-Players CAR-T-Therapies-Market-Distribution-by-Type-of-Partnership
CAR-T-Therapies-Market-Distribution-by-Type-of-Therapy 	CAR-T-Therapies-Market-Market-Forecast CAR-T-Therapies-Market-Cost-Price-Analysis  

 

Overview

Cancer is one of the leading causes of death worldwide, accounting for an estimated 1.8 million mortalities in 2020, in the US alone. Moreover, according to the World Health Organization, the number of newly diagnosed cancer cases is anticipated to grow by 70%, worldwide, over the next 20 years. Till date, it has been established that conventional treatment options, which include chemotherapy, radiation therapy, and surgery, are limited when it comes to treating late-stage cancers. Immunotherapy, especially T cell-based products, has emerged as a viable and promising treatment option, having demonstrated the capability to selectively target and eliminate tumor cells. Over time, the approval and clinical success of several chimeric antigen receptor (CAR) transduced T-cell based immunotherapy candidates, have inspired numerous research groups across the world, to focus their efforts on this relatively novel class of anticancer therapies. In fact, CAR-T cell therapies are presently considered among the most promising therapeutics available to treat various types of hematological malignancies and solid tumors. In addition, T-cell based therapies featuring CAR constructs designed against pathogenic entities that are characteristic of a number of non-oncological indications, are also under investigation.

Currently, there are four approved CAR-T cell therapies, namely KYMRIAH® (Novartis), YESCARTA® (Gilead Sciences), TECARTUS™ (Gilead Sciences) and BREYANZI® (Bristol Myers Squibb / Juno Therapeutics). Owing to advances in fundamental research on disease biology, a myriad of viable biological targets that can be drugged using CARs have been identified.  Leveraging available data, industry stakeholders are actively strengthening their respective pipelines; there are more than 755 CAR-T cell-based product candidates that are presently being evaluated in clinical and preclinical trials. This upcoming class of biologics is also driven by the availability of several innovative technology platforms that enable genetic manipulation and cell therapy development, and lucrative capital investments from both public and private investors. With multiple therapeutic leads in the mid to late-stages of development (phase II and above), and soon anticipated to enter the market, we are led to believe that the CAR-T cell therapy market is likely to witness significant growth in the foreseen future.

Scope of the Report

The “CAR-T Cell Therapies Market (3rd Edition) by Target Indications (Non-Hodgkin’s Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Hepatocellular Carcinoma and Colorectal Cancer), Target Antigens (CD19, BCMA, CD19 / CD22, GPC3 and EGFR), Key Players and Key Geographies (North America, Europe, Asia Pacific, Latin America, Middle East and North Africa, and Rest of the World) – Global Forecast 2021-2030” report features an extensive study of the current market landscape and the future potential of CAR-T cell therapies. The report highlights the efforts of both industry players and academic organizations in this rapidly evolving segment of the biopharmaceutical industry. Amongst other elements, the report features the following:

  • A detailed assessment of the current market landscape of CAR-T cell therapies based on the type of developer (industry / non-industry), phase of development (preclinical, phase I, phase I/II, phase II, phase III and approved), therapeutic area (hematological cancer, solid tumor and others), target therapeutic indication (acute lymphoblastic leukemia, non-Hodgkin lymphoma, multiple myeloma, acute myeloid leukemia, brain cancer, chronic lymphocytic leukemia, pancreatic cancer, liver cancer, lung cancer, stomach cancer, ovarian cancer, breast cancer, mesothelioma, colon cancer, Hodgkin lymphoma, sarcoma, bone cancer, melanoma, and others), key target antigen (CD19, BCMA, CD22, CD20, GD2, Meso, CD38, CD123, MUC1, CD30, HER2, GPC3, CD33, EGFR, EGFRvIII, PD-L1, PSMA and others), source of T-cells (autologous / allogeneic), route of administration (intravenous, intratumor, intraperitoneal, intrapleural, intraventricular and others), dose frequency (single dose, multiple dose and split dose), target patient segment (children, adults and seniors), and type of therapy (monotherapy and combination therapy). Further, the chapter provides a list of the most active players (in terms of number of pipeline candidates) and an insightful logo landscape, highlighting product developers in North America, Europe and the Asia Pacific.
  • Detailed profiles of marketed and mid to late stage clinical products (phase I/II or above); each profile features an overview of the therapy, its mechanism of action, dosage information, details on the cost and sales information (wherever available), clinical development plan, and key clinical trial results.
  • An analysis of the CAR constructs of clinical-stage CAR-T therapies based on the generation of CAR-T therapy (first generation, second generation, third generation and fourth generation), type of binding domain (murine, humanized, fully human and rabbit derived), type of vector (lentivirus, retrovirus, mRNA and other vectors) and type of co-stimulatory domain used.
  • An analysis highlighting the key opinion leaders (KOLs) in this domain. It features a 2×2 representation highlighting the KOLs shortlisted based on their contributions (in terms of involvement in various clinical studies) to this field, and a schematic world map representation, indicating the geographical location of eminent scientists / researchers involved in the development of CAR-T cell therapies.
  • An analysis of the completed, ongoing, and planned clinical studies of various CAR-T cell therapies, based on trial registration year and geographical location of the clinical trial centers. In addition, we have provided a list of factors that have influenced the growth of CAR-T therapies, especially in China.
  • An overview of the focus areas of therapy developers (in terms of target disease indication), including an assessment of the opportunity (in terms of revenue generation potential from therapy sales) across oncological and non-oncological disease indications.
  • A detailed discussion on innovative technology platforms that are being used for the development of CAR-T cell therapies, along with profiles of key technology providers, and a competitiveness analysis of different gene editing platforms (used for the development of CAR-T cell therapies), based on various parameters, such as ease of system design, cost of technology, level of toxicity and efficiency of technology.
  • An analysis of the partnerships that have been established in the recent past, covering R&D agreements, license agreements (specific to technology platforms and product candidates), product development and commercialization agreements, manufacturing agreements, clinical trial collaborations, product supply management agreements, joint ventures and others.
  • An analysis of the investments that have been made into companies that have proprietary CAR-T cell based products / technologies, including seed financing, venture capital financing, capital raised from IPOs and subsequent offerings, grants and debt financing.
  • A case study on manufacturing cell therapy products, highlighting the key challenges, and a detailed list of contract service providers and in-house manufacturers involved in this space.
  • An elaborate discussion on various factors that form the basis for the pricing of cell-based therapies. It features different models / approaches that a pharmaceutical company may choose to adopt to decide the price of a CAR-T cell based therapies that is likely to be marketed in the coming years.
  • An analysis of the prevalent and emerging trends in this domain, as represented on the social media platform, Twitter, highlighting the yearly trend of tweets, most frequently talked about product candidates, popular disease indications, target antigens, and prolific authors and social media influencers.
  • A review of the key promotional strategies that have been adopted by the developers of the marketed T-cell therapies, namely KYMRIAH® and YESCARTA®.

One of the key objectives of the report was to estimate the existing market size and identify potential growth opportunities for CAR-T cell therapies over the coming decade. Based on several parameters, such as target consumer segments, region specific adoption rates and expected prices of such products, we have developed informed estimates of the likely evolution of the market over the period 2021-2030. The report also includes likely sales forecasts of CAR-T cell therapies that are already marketed or in the late stages of development. Additionally, it features market size projections for the overall CAR-T cell therapy market, wherein opportunity has been segmented across [A] target indications (non-Hodgkin’s lymphoma, multiple myeloma, chronic lymphocytic leukemia, acute lymphoblastic leukemia, follicular lymphoma, mantle cell lymphoma, hepatocellular carcinoma and colorectal cancer), [B] target antigens (CD19, BCMA, CD19 / CD22, GPC3 and EGFR) and [C] key geographies (North America (US and Canada), Europe (UK, Germany, France, Italy, Spain and rest of EU), Asia Pacific (China, Japan, Australia), Latin America, Latin America, Middle East and North Africa and rest of the world). In order to account for future uncertainties and to add robustness to our model, we have provided three market forecast scenarios namely the conservative, base and optimistic scenarios, which represent different tracks of the industry’s evolution.

The opinions and insights presented in this study were influenced by discussions conducted with several stakeholders in this domain. The report features detailed transcripts of interviews held with the following individuals:

  • Tim Oldham (Chief Executive Officer, Cell Therapies)
  • Vincent Brichard (Vice President, Immuno-Oncology, Celyad)
  • Xian-Bao Zhan (Professor of Medicine and Director, Department of Oncology, Changhai Hospital)
  • Troels Jordansen (Chief Executive Officer, Glycostem Therapeutics)
  • Wei (William) Cao (Chief Executive Officer, Gracell Biotechnologies)
  • Adrian Bot (Vice President, Scientific Affairs, Kite Pharma)
  • Aino Kalervo (Competitive Intelligence Manager, Strategy & Business Development, Theravectys)
  • Miguel Forte (Chief Operating Officer, TxCell)
  • Enkhtsetseg Purev (Assistant Professor of Medicine, University of Colorado)
  • Brian Dattilo (Manager of Business Development, Waisman Biomanufacturing)

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

Key Questions Answered

  • What are the prevalent R&D trends in CAR-T cell therapies domain?
  • What are the key therapeutic areas for which CAR-T cell therapies are being / have been developed?
  • What are the various challenges being faced by stakeholders engaged in this domain?
  • Who are the leading industry and non-industry players in this market?
  • Which are the key geographies where extensive research on CAR-T cell therapies is being conducted?
  • Who are the key investors in this domain? 
  • Who are the key opinion leaders / experts that can help in driving the development efforts?
  • What kind of partnership models are commonly adopted by industry stakeholders? 
  • What kind of contract manufacturing support is available for CAR-T cell therapies, across different regions?
  • What kind of promotional strategies are likely to be adopted for CAR-T cell therapies that are approved and commercialized in future?
  • What are the factors that are likely to influence the evolution of this upcoming market?
  • How is the current and future market opportunity likely to be distributed across key market segments? 

Contents

Chapter Outlines

Chapter 2 provides an executive summary of the insights captured during our research. It offers a high-level view on the likely evolution of the CAR-T cell therapy market in the short to mid-term and long term.

Chapter 3 provides a general overview of CAR-T cell therapies. In this section, we have briefly discussed the conventional forms of therapy that are being used for the treatment of various oncological indications. Further, it includes a discussion on the advent and historical evolution of cancer immunotherapy, general manufacturing procedure of CAR-T cell therapies, factors supporting the growing popularity of CAR-T cell based therapies and the challenges associated with such therapies. 

Chapter 4 provides insights on the popularity of CAR-T cell therapies on the social media platform, Twitter. The section highlights the yearly distribution of tweets posted on the platform in the time period 2012-2019, and the most significant events responsible for increase in the volume of tweets each year. Additionally, the chapter highlights the most frequently talked about product candidates, popular disease indications, target antigens, and prolific authors and social media influencers.

Chapter 5 features an assessment of  the CAR-T cell therapies that are currently approved or in different stages of development. It features a detailed analysis of pipeline molecules with respect to the type of developer (industry / non-industry), phase of development (preclinical, phase I, phase I/II, phase II, phase III and approved), therapeutic area (hematological cancer, solid tumor and others), target therapeutic indication (acute lymphoblastic leukemia, non-Hodgkin lymphoma, multiple myeloma, acute myeloid leukemia, brain cancer, chronic lymphocytic leukemia, pancreatic cancer, liver cancer, lung cancer, stomach cancer, ovarian cancer, breast cancer, mesothelioma, colon cancer, Hodgkin lymphoma, sarcoma, bone cancer, melanoma, and others), key target antigen (CD19, BCMA, CD22, CD20, GD2, Meso, CD38, CD123, MUC1, CD30, HER2, GPC3, CD33, EGFR, EGFRvIII, PD-L1, PSMA and others), source of T-cells (autologous / allogeneic), route of administration (intravenous, intratumor, intraperitoneal, intrapleural, intraventricular and others), dose frequency (single dose, multiple dose and split dose), target patient segment (children, adults and seniors), and type of therapy (monotherapy and combination therapy). Further, the chapter provides a list of the most active players (in terms of number of pipeline candidates) and an insightful logo landscape, highlighting product developers in North America, Europe and the Asia Pacific. 

Chapter 6 presents a collection of key insights derived from the study. It includes an insightful  representation highlighting the most popular targets of CAR-T therapies in hematological cancer and solid tumor space. To offer due credit to the work of eminent researchers in this domain, we have mapped the presence of key opinion leaders (who are involved in this field of research) across the globe. In addition, we have presented an analysis of the CAR constructs being used in the clinical CAR-T therapies on the basis of generation of CAR-T therapies (first generation, second generation, third generation and fourth generation), type of binding domain (murine, humanized, fully human and rabbit derived), type of vector (lentivirus, retrovirus, mRNA and other vectors) and type of co-stimulatory domain used.

Chapter 7 presents an analysis of the clinical trials of CAR-T registered across the world, between 2009 and 2019, highlighting the year wise trend and the distribution across different geographies. In addition, we have provided a detailed list of factors that have influenced the growth of CAR-T therapies market in China.

Chapter 8 provides detailed profiles of marketed and mid to late stage CAR-T therapies (phase I/II or above). Each profile features an overview of the therapy, its mechanism of action, dosage information, details on the cost and sales information (wherever available), clinical development plan, and key clinical trial results.

Chapter 9 includes an overview of  the most commonly targeted therapeutic indications, including hematological cancers and solid tumors and features brief discussions on the CAR-T cell therapies being developed against them. The section also highlights key epidemiological facts and the currently available treatment options for each indication.

Chapter 10 provides a list of technology platforms that are either available in the market or under designed for the development of CAR-T cell therapies and a detailed discussion on innovative technology platforms that are being used for the development of T-cell therapies, along with profiles of key technology providers, and a relative competitiveness analysis of different gene editing platforms (used for the development of CAR-T cell therapies), based on various parameters, such as ease of system design, cost of technology, level of toxicity and efficiency of technology.

Chapter 11 features a analysis of the various collaborations and partnerships that have been inked amongst players in this market, in the past few years. Further, the partnership activity in this domain has been analyzed on the basis of the type of partnership model (R&D collaborations, license agreements (specific to technology platforms and product candidates), product development and commercialization agreements, manufacturing agreements, clinical trial collaborations, product supply management agreements and others), companies involved, type of therapy, prominent product candidates involved and regional distribution of the collaborations.

Chapter 12 provides details on the investments and grants that have been awarded to players focused on the development of CAR-T cell therapies. It includes a detailed analysis of the funding instances that have taken place in the period between 2000 to 2020, highlighting the growing interest of venture capital (VC) community and other strategic investors in this domain.

Chapter 13 provides insights on cell therapy manufacturing, highlighting the current challenges in this domain, and the pre-requisites for owning and maintaining cell therapy manufacturing sites. It includes a list of cell therapy manufacturers, covering both contract manufacturing organizations and companies with in-house manufacturing capabilities. For the players mentioned in the chapter, we have included details on location of various manufacturing facilities, the products being manufactured, scale of operation and compliance to cGMP standards.

Chapter 14 highlights our views on the various factors that must be taken into consideration while deciding the prices of CAR-T cell-based therapies. It features discussions on different models / approaches that a pharmaceutical company may choose to follow to decide the price at which their CAR-T cell-based therapy product can be marketed. Additionally, we have provided a brief overview of the reimbursement consideration for CAR-T cell therapies and a case study on the National Institute for Health and Care Excellence (NICE) appraisal of CAR-T therapy.

Chapter 15 features an elaborate discussion on the future commercial opportunity offered by CAR-T cell therapies. It provides an informed market forecast analysis for molecules that are approved or are in phase I/II, phase II and phase III of development, taking into consideration the target patient population, existing / future competition, likely adoption rates and the likely price of different therapies. The chapter also presents a detailed market segmentation on the basis of [A] target indications (non-Hodgkin’s lymphoma, multiple myeloma, chronic lymphocytic leukemia, acute lymphoblastic leukemia, follicular lymphoma, mantle cell lymphoma, hepatocellular carcinoma and colorectal cancer), [B] target antigens (CD19, BCMA, CD19 / CD22, GPC3 and EGFR) and [C] key geographies (North America (US and Canada), Europe (UK, Germany, France, Italy, Spain and rest of EU), Asia Pacific (China, Japan, Australia), Latin America, Latin America, Middle East and North Africa and rest of the world).

Chapter 16 highlights the key promotional strategies that are being implemented by the developers of the marketed products, KYMRIAH® and YESCARTA®. The promotional aspects covered in the chapter include details that are provided on the product website (covering key messages for patients and healthcare professionals), patient support offerings and informative downloadable content.

Chapter 17 includes brief company profiles of the leading players in the CAR-T cell therapy market. Each company profile includes an overview of the developer and brief description of the product portfolio specific to technology portfolio (if available), recent developments related to CAR-T cell therapy and manufacturing capabilities of the companies. Additionally, we have provided details of the strategic / venture capital investments made in these companies.

Chapter 18 is a summary of the overall report. In this chapter, we have provided a list of key takeaways from the report, and expressed our independent opinion related to the research and analysis described in the previous chapters.

Chapter 19 is a collection of transcripts of interviews conducted with key stakeholders in the market. In this chapter, we have presented the details of our conversations with Tim Oldham (Chief Executive Officer, Cell Therapies), Vincent Brichard (Vice President, Immuno-Oncology, Celyad), Xian-Bao Zhan (Professor of Medicine and Director, Department of Oncology, Changhai Hospital), Troels Jordansen (Chief Executive Officer, Glycostem Therapeutics), Wei (William) Cao (Chief Executive Officer, Gracell Biotechnologies), Adrian Bot (Vice President, Scientific Affairs, Kite Pharma), Aino Kalervo (Competitive Intelligence Manager, Strategy & Business Development, Theravectys), Miguel Forte (Chief Operating Officer, TxCell), Enkhtsetseg Purev (Assistant Professor of Medicine, University of Colorado) and Brian Dattilo (Manager of Business Development, Waisman Biomanufacturing).

Chapter 20 is an appendix, which provides tabulated data and numbers for all the figures included in the report.

Chapter 21 is an appendix, which contains the list of companies and organizations mentioned in the report.

Table Of Contents

1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Key Questions Answered
1.4. Chapter Outlines

2. EXECUTIVE SUMMARY

3. INTRODUCTION
3.1. Chapter Overview
3.2. Pillars of Cancer Therapy
3.3. Overview of Immunotherapy
3.4. Fundamentals of Cancer Immunotherapy
3.5. Classification of Cancer Immunotherapies
3.5.1. By Mechanism of Action
3.5.1.1. Active Immunotherapy
3.5.1.2. Passive Immunotherapy

3.5.2. By Type of Target
3.5.3. By Approach
3.5.3.1. Activation and Suppression Immunotherapy

3.5.4. By Product Class
3.5.4.1. Monoclonal Antibodies
3.5.4.2. Bispecific Antibodies
3.5.4.3. Cytokines
3.5.4.4. Oncolytic Virus Therapy
3.5.4.5. Therapeutic Cancer Vaccines
3.5.4.6. Cell-based Therapies

3.6. T-Cell Immunotherapies
3.6.1. Historical Evolution
3.6.2. Key Considerations for Developing T-Cell Immunotherapies
3.6.3. Strategies Employed for the Redirection of T-Cells
3.6.4. Manufacturing of Engineered T-Cells
3.6.5. T-Cell Transduction and Transfection Methods
3.6.5.1. Retroviral Vectors
3.6.5.2. Lentiviral Vectors
3.6.5.3. Non-viral Transfection Methods

3.7. Chimeric Antigen Receptor T-Cell Therapy (CAR-T)
3.7.1. History of Development
3.7.2. Anatomical Layout of CAR
3.7.2.1. Ectodomain
3.7.2.2. Transmembrane (TM) Domain
3.7.2.3. Endodomain

3.7.3. Development of CAR-T Cells
3.7.4. Universal CAR-T Cells
3.7.5. Route of Administration of CAR-T Cell Therapies
3.7.6. Case Study: CD19 CAR-T Cell Therapies
3.7.6.1. Other Important Biological Targets for CAR Development

3.7.7. Challenges Associated with CAR-T Cell Therapies
3.7.7.1. Competitive Risks
3.7.7.2. Clinical Risks
3.7.7.3. Regulatory Risks
3.7.7.4. Commercial Risks

4. EMERGING TRENDS ON SOCIAL MEDIA
4.1. Chapter Overview
4.2. CAR-T Cell Therapies: Trends on Twitter
4.2.1. Historical Trend in Volume of Tweets
4.2.2. Trending Words / Phrases on Twitter
4.2.3. Most Popular Drugs on Twitter
4.2.4. Most Prolific Authors on Twitter
4.2.5. Most Popular Indications and Target Antigens

5. MARKET LANDSCAPE
5.1. Chapter Overview
5.2. CAR-T Cell Therapies: Overall Market Landscape
5.2.1. Analysis by Type of Developer
5.2.2. Analysis by Phase of Development
5.2.3. Analysis by Therapeutic Area
5.2.4. Analysis by Popular Target Indications
5.2.5. Analysis by Popular Target Antigens
5.2.6. Analysis by Source of T-Cells
5.2.7. Analysis by Route of Administration
5.2.8. Analysis by Dose Frequency
5.2.9. Analysis by Target Patient Segment
5.2.10. Analysis by Type of Therapy
5.2.11. Key Industry Players: Distribution by Number of Therapies in Pipeline
5.2.12. Key Non-Industry Players: Distribution by Number of Therapies in Pipeline

6. KEY INSIGHTS
6.1. Chapter Overview
6.2. CAR-T Cell Therapies: Competitive Analysis by Popular Target Antigens
6.2.1. Popular Targets Related to Hematological Malignancies
6.2.1.1. Competitive Landscape of CD19 CAR-T Cell Therapies
6.2.1.2. Clinical Trial Results of Prominent CD19 CAR-T Cell Therapies
6.2.1.3. Competitive Landscape of BCMA CAR-T Cell Therapies
6.2.1.4. Clinical Trial Results of Prominent BCMA CAR-T Cell Therapies

6.2.2. Popular Targets Related to Solid Tumors 
6.2.2.1. Competitive Landscape of Meso CAR-T Cell Therapies
6.2.2.2. Clinical Trial Results of Prominent Meso CAR-T Cell Therapies
6.2.2.3. Competitive Landscape of GD2 CAR-T Cell Therapies
6.2.2.4. Clinical Trial Results of Prominent GD2 CAR-T Cell Therapies

6.3. CAR-T Cell Therapies: Key Opinion Leaders
6.3.1. CAR-T Cell Therapies: Most Prominent Key Opinion Leaders

6.4. CAR-T Cell Therapies: CAR Construct Analysis
6.4.1. Analysis by Generation of CAR
6.4.2. Analysis by Type of scFv Antibody
6.4.3. Analysis by Type of Vector
6.4.4. Analysis by Type of Co-Stimulatory Domain(s)

7. CLINICAL TRIAL ANALYSIS
7.1. Chapter Overview
7.2. CAR-T Cell Therapies: Clinical Trial Analysis
7.2.1. Methodology
7.2.2. Analysis by Trial Registration Year
7.2.3. Geographical Analysis by Number of Registered Trials
7.2.4. Case Study: CAR-T Cell Therapy Market in China
7.2.4.1. Factors Contributing to the Growth of CAR-T Cell Therapy Trials in China

8. CAR-T CELL THERAPY PROFILES
8.1. Chapter Overview
8.2. KYMRIAH® / Tisagenlecleucel / CTL019 (Novartis)
8.2.1. Therapy Overview
8.2.1.1. History of Development
8.2.2. Current Status of Development 
8.2.3. Key Clinical Trial Results
8.2.4. Dosage Regimen, Price and Manufacturing

8.3. YESCARTA® / Axicabtagene Ciloleucel / KTE-C19 (Kite Pharma)
8.3.1. Therapy Overview
8.3.1.1. History of Development
8.3.2. Current Status of Development 
8.3.3. Key Clinical Trial Results
8.3.4. Dosage Regimen, Price and Manufacturing

8.4. TECARTUS® / Brexucabtagene Autoleucel (Kite Pharma)
8.4.1. Therapy Overview
8.4.2. Current Status of Development 
8.4.3. Key Clinical Trial Results
8.4.4. Dosage Regimen, Price and Manufacturing

8.5. JCAR (Juno Therapeutics (a Bristol Myers Squibb Company))
8.5.1. Therapy Overview
8.5.1.1. CAR-T Design
8.5.2. Current Status of Development 
8.5.3. Key Clinical Results
8.5.3.1. JCAR014
8.5.3.2. JCAR017
8.5.3.3. JCAR018
8.5.3.4. JCARH125
8.5.4. Dosage Regimen and Manufacturing

8.6. Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol-Myers Squibb)
8.6.1. Therapy Overview
8.6.2. Current Status of Development 
8.6.3. Key Clinical Trial Results
8.6.4. Dosage Regimen and Manufacturing

8.7. Ciltacabtagene Autoleucel / LCAR-B38M CAR-T / JNJ-68284528 (Nanjing Legend Biotech / Janssen Biotech)
8.7.1. Therapy Overview
8.7.2. Current Status of Development 
8.7.3. Key Clinical Trial Results
8.7.4. Dosage Regimen and Manufacturing

8.8. TBI-1501 / CD19 CAR-T Cell Therapy (Takara Bio)
8.8.1. Therapy Overview
8.8.2. Current Status of Development 
8.8.3. Key Clinical Trial Results
8.8.4. Dosage Regimen and Manufacturing

8.9. Next Generation CAR-T Cell therapies (Autolus)
8.9.1. Therapy Overview
8.9.2. Current Status of Development 
8.9.3. Key Clinical Trial Results
8.9.3.1. AUTO1
8.9.3.2. AUTO3
8.9.4. Dosage Regimen and Manufacturing

8.10. CAR-T Cell Therapies (Sinobioway Cell Therapy)
8.10.1. Therapy Overview
8.10.2. Current Status of Development 
8.10.3. Dosage Regimen and Manufacturing

9. KEY THERAPEUTIC AREAS FOR CAR-T CELL THERAPIES
9.1. Chapter Overview
9.2. Hematological Malignancies
9.2.1. Leukemia and Lymphoma
9.2.1.1. Leukemia: Introduction and Epidemiology
9.2.1.1.1. Acute Myeloid Leukemia (AML)
9.2.1.1.2. Chronic Myeloid Leukemia (CML)
9.2.1.1.3. Acute Lymphocytic Leukemia (ALL)
9.2.1.1.4. Chronic Lymphocytic Leukemia (CLL)

9.2.1.2. Lymphoma: Introduction and Epidemiology
9.2.1.3. Current Treatment Landscape
9.2.1.3.1. Targeted Therapies

9.2.1.4. CAR-T Cell Therapies and Affiliated Research Landscape
9.2.1.4.1. CAR-T Cell Therapies and Leukemia / Lymphoma

9.2.2. Multiple Myeloma
9.2.2.1. Introduction and Epidemiology
9.2.2.2. Current Treatment Landscape
9.2.2.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3. Solid Tumors
9.3.1. Metastatic Melanoma
9.3.1.1. Introduction and Epidemiology
9.3.1.2. Current Treatment Landscape
9.3.1.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.2. Lung Cancer
9.3.2.1. Introduction and Epidemiology
9.3.2.2. Current Treatment Landscape
9.3.2.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.3. Pancreatic Cancer
9.3.3.1. Introduction and Epidemiology
9.3.3.2. Current Treatment Landscape
9.3.3.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.4. Liver Cancer
9.3.4.1. Introduction and Epidemiology
9.3.4.1. Current Treatment Landscape
9.3.4.2. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.5. Breast Cancer
9.3.5.1. Introduction and Epidemiology
9.3.5.2. Current Treatment Landscape
9.3.5.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.6. Ovarian Cancer
9.3.6.1. Introduction and Epidemiology
9.3.6.2. Current Treatment Landscape
9.3.6.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.7. Bladder Cancer
9.3.7.1. Introduction and Epidemiology
9.3.7.2. Current Treatment Landscape
9.3.7.3. CAR-T Cell Therapies and Affiliated Research Landscape

9.3.8. Kidney Cancer
9.3.8.1. Introduction and Epidemiology
9.3.8.2. Current Treatment Landscape
9.3.8.3. CAR-T Cell Therapies and Affiliated Research Landscape

10. EMERGING TECHNOLOGIES
10.1. Chapter Overview
10.2. Genome Editing Technologies
10.2.1. Applications of Genome Editing Technologies 
10.2.2. Emerging Technology Platforms for CAR-T Cell Therapy Development and Production
10.2.2.1. CRISPR / Cas9 System
10.2.2.1.1. Key Components and Function
10.2.2.1.2. Mechanism of Action
10.2.2.1.3. Targeting Efficiency and Challenges
10.2.2.1.4. Next-GEN CRISPR Technology
10.2.2.1.5. Technology Providers
10.2.2.1.5.1. Editas Medicine
10.2.2.1.5.2. Intellia Therapeutics
10.2.2.1.5.3. CRISPR Therapeutics
10.2.2.1.5.4. Beam Therapeutics
10.2.2.1.5.5. Gracell Biotechnologies

10.2.2.2. TALENs
10.2.2.2.1. Key Components and Function
10.2.2.2.2. Mechanism of Action
10.2.2.2.3. Advantages and Challenges
10.2.2.2.4. Technology Providers
10.2.2.2.4.1. Cellectis
10.2.2.2.4.2. Editas Medicine

10.2.2.3. megaTAL
10.2.2.3.1. Technology Providers
10.2.2.3.1.1. bluebird bio

10.2.2.4. Zinc Finger Nuclease
10.2.2.4.1. Technology Providers
10.2.2.4.1.1. Sangamo Therapeutics

10.2.3. Competitive Analysis: Gene Editing Platforms

10.3. Designing CAR-T Cell Therapies with Improved Characteristics
10.3.1. Technologies for Targeting Multiple Cancers
10.3.1.1. Antibody Coupled T-Cell Receptor
10.3.1.1.1. Unum Therapeutics

10.3.1.2. NKR-T Platform
10.3.1.2.1. Celyad Oncology
10.3.1.2.2. Glycostem

10.3.2. Technologies for Improved Safety
10.3.2.1. Armored CAR and EGFRt Technology
10.3.2.1.1. Juno Therapeutics

10.3.2.2. RheoSwitch Therapeutic System
10.3.2.2.1. Intrexon

10.3.2.3. Inducible Caspase 9 Safety Switch
10.3.2.3.1. Bellicum Pharmaceuticals
10.3.2.3.1.1. CaspaCIDe Technology
10.3.2.3.1.2. CIDeCAR Technology
10.3.2.3.1.3. GoCAR-T Technology

10.3.2.3. On-Off Switch, Multiple Companies
10.3.2.3.1. Inhibitory CAR (iCAR) (Juno Therapeutics)
10.3.2.3.2. On-Off Switch (Theravectys)

10.3.2.4. Other Technologies to Improve CAR-T Safety

10.3.3. Allogeneic Technologies
10.3.3.1. CIK CAR-T Cells (Formula Pharmaceuticals)
10.3.3.2. Allogeneic Platform (Celyad)
10.3.3.3. Allogeneic Platform (Cellectis)

11. PARTNERSHIPS AND COLLABORATIONS
11.1. Chapter Overview
11.2. Partnership Models
11.3. CAR-T Cell Therapy Market: List of Partnerships and Collaborations
11.3.1. Analysis by Year of Partnership
11.3.2. Analysis by Type of Partnership
11.3.3. Most Popular Products
11.3.4. Most Active Industry Players: Analysis by Number of Partnerships
11.3.5. Most Active Non-Industry Players: Analysis by Number of Partnerships
11.3.6. Most Active Contract Manufacturers: Analysis by Number of Manufacturing 
11.3.7. Regional Analysis
11.3.8. Intercontinental and Intracontinental Agreements

12. FUNDING AND INVESTMENT ANALYSIS
12.1. Chapter Overview
12.2. Types of Funding
12.3. CAR-T Cell Therapy Market: Funding and Investment Analysis
12.3.1. Analysis by Year of Investment
12.3.2. Analysis by Amount Invested
12.3.3. Analysis by Type of Funding
12.3.4. Most Active Players: Analysis by Number of Funding Instances
12.3.5. Analysis by Type of Investor
12.3.6. Most Active Investors: Analysis by Number of Funding Instances
12.3.7. Regional Analysis by Amount Invested

13. CASE STUDY: CELL THERAPY MANUFACTURING
13.1. Chapter Overview
13.2. Overview of Cell Therapy Manufacturing
13.3. Cell Therapy Manufacturing Models
13.3.1. Centralized Manufacturing Model
13.3.2. Decentralized Manufacturing Model

13.4. Scalability of Cell Therapy Manufacturing Processes
13.4.1. Scale-Up
13.4.2. Scale-Out

13.5. Types of Cell Therapy Manufacturers
13.6. Key Challenges Associated with Manufacturing of Cell Therapies
13.7. Important Factors for Cell Therapy Manufacturing
13.7.1. Characterization
13.7.2. Cost of Goods

13.8. Automation of Cell Therapy Manufacturing Process
13.9. Cell Therapy Manufacturing Supply Chain
13.10. Companies with In-House Capabilities
13.11. Contract Manufacturers
13.12. Regulatory Landscape

14. COST PRICE ANALYSIS
14.1. Chapter Overview
14.2. Factors Contributing to the High Price of Cell / Gene Therapies
14.3. Pricing Models for CAR-T Cell Therapies
14.3.1. Based on Associated Costs
14.3.2. Based on Availability of Competing Products
14.3.3. Based on Target Patient Segment
14.3.4. Based on the Opinions of Industry Experts

14.4. Reimbursement-related Considerations for CAR-T Cell Therapies
14.4.1. Case Study: The National Institute for Health and Care Excellence (NICE) Appraisal of CAR-T Therapies

15. MARKET SIZING AND OPPORTUNITY ANALYSIS
15.1. Chapter Overview
15.2. Scope and Limitations
15.3. Key Assumptions and Forecast Methodology
15.4. Overall CAR-T Cell Therapy Market, 2021-2030
15.4.1. CAR-T Cell Therapies Market: Distribution by Target Indication
15.4.2. CAR-T Cell Therapies Market: Distribution by Target Antigen
15.4.3. CAR-T Cell Therapies Market: Distribution by Key Players
15.4.4. CAR-T Cell Therapies Market: Distribution by Geography
15.4.5. Product Wise Sales Forecast

15.4.5.1. KYMRIAH® (Novartis)
15.4.5.1.1. Target Patient Population
15.4.5.1.2. Sales Forecast (USD Million)
15.4.5.1.3. Net Present Value (USD Million)
15.4.5.1.4. Value Creation Analysis

15.4.5.2. YESCARTA® (Gilead Sciences)
15.4.5.2.1. Target Patient Population
15.4.5.2.2. Sales Forecast (USD Million)
15.4.5.2.3. Net Present Value (USD Million)
15.4.5.2.4. Value Creation Analysis

15.4.5.3. Tecartus / Brexucabtagene Autoleucel (Gilead Sciences)
15.4.5.3.1. Target Patient Population
15.4.5.3.2. Sales Forecast (USD Million)
15.4.5.3.3. Net Present Value (USD Million)
15.4.5.3.4. Value Creation Analysis

15.4.5.4. BREYANZI® / Lisocabtagene Maraleucel / JCAR017JCAR017 (Bristol Myers Squibb / Juno Therapeutics)
15.4.5.4.1. Target Patient Population
15.4.5.4.2. Sales Forecast (USD Million)
15.4.5.4.3. Net Present Value (USD Million)
15.4.5.4.4. Value Creation Analysis

15.4.5.5. Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb)
15.4.5.5.1. Target Patient Population
15.4.5.5.2. Sales Forecast (USD Million)
15.4.5.5.3. Net Present Value (USD Million)
15.4.5.5.4. Value Creation Analysis

15.4.5.6. Ciltacabtagene Autoleucel / LCAR-B38M CAR-T (Nanjing Legend Biotech / Janssen)
15.4.5.6.1. Target Patient Population
15.4.5.6.2. Sales Forecast (USD Million)
15.4.5.6.3. Net Present Value (USD Million)
15.4.5.6.4. Value Creation Analysis

15.4.5.7. MB-CART19.1 (Miltenyi Biotec)
15.4.5.7.1. Target Patient Population
15.4.5.7.2. Sales Forecast (USD Million)
15.4.5.7.3. Net Present Value (USD Million)
15.4.5.7.4. Value Creation Analysis

15.4.5.8. Descartes-11 (Cartesian Therapeutics)
15.4.5.8.1. Target Patient Population
15.4.5.8.2. Sales Forecast (USD Million)
15.4.5.8.3. Net Present Value (USD Million)
15.4.5.8.4. Value Creation Analysis

15.4.5.9. CD19 CAR-T (Sinobioway Cell Therapy)
15.4.5.9.1. Target Patient Population
15.4.5.9.2. Sales Forecast (USD Million)
15.4.5.9.3. Net Present Value (USD Million)
15.4.5.9.4. Value Creation Analysis

15.4.5.10. AUTO1 (Autolus)
15.4.5.10.1. Target Patient Population
15.4.5.10.2. Sales Forecast (USD Million)
15.4.5.10.3. Net Present Value (USD Million)
15.4.5.10.4. Value Creation Analysis

15.4.5.11. AUTO3 (Autolus)
15.4.5.11.1. Target Patient Population
15.4.5.11.2. Sales Forecast (USD Million)
15.4.5.11.3. Net Present Value (USD Million)
15.4.5.11.4. Value Creation Analysis

15.4.5.12. GPC3 CAR-T (Shanghai GeneChem)
15.4.5.12.1. Target Patient Population
15.4.5.12.2. Sales Forecast (USD Million)
15.4.5.12.3. Net Present Value (USD Million)
15.4.5.12.4. Value Creation Analysis

15.4.5.13. BCMA CAR-T (The Pregene (ShenZhen) Biotechnology)
15.4.5.13.1. Target Patient Population
15.4.5.13.2. Sales Forecast (USD Million)
15.4.5.13.3. Net Present Value (USD Million)
15.4.5.13.4. Value Creation Analysis

15.4.5.14. CD19 CAR-T (The Pregene (ShenZhen) Biotechnology)
15.4.5.14.1. Target Patient Population
15.4.5.14.2. Sales Forecast (USD Million)
15.4.5.14.3. Net Present Value (USD Million)
15.4.5.14.4. Value Creation Analysis

15.4.5.15. CD19 CAR-T (Shanghai Bioray Laboratory)
15.4.5.15.1. Target Patient Population
15.4.5.15.2. Sales Forecast (USD Million)
15.4.5.15.3. Net Present Value (USD Million)
15.4.5.15.4. Value Creation Analysis

15.4.5.16. Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicine Technology)
15.4.5.16.1. Target Patient Population
15.4.5.16.2. Sales Forecast (USD Million)
15.4.5.16.3. Net Present Value (USD Million)
15.4.5.16.4. Value Creation Analysis

15.4.5.17. PCAR-019 (PersonGen BioTherapeutics)
15.4.5.17.1. Target Patient Population
15.4.5.17.2. Sales Forecast (USD Million)
15.4.5.17.3. Net Present Value (USD Million)
15.4.5.17.4. Value Creation Analysis

15.4.5.18. TBI-1501 (Takara Bio)
15.4.5.18.1. Target Patient Population
15.4.5.18.2. Sales Forecast (USD Million)
15.4.5.18.3. Net Present Value (USD Million)
15.4.5.18.4. Value Creation Analysis

15.4.5.19. IM19 CAR-T (Beijing Immunochina Medical Science & Technology)
15.4.5.19.1. Target Population
15.4.5.19.2. Sales Forecast (USD Million)
15.4.5.19.3. Net Present Value (USD Million)
15.4.5.19.4. Value Creation Analysis

15.4.5.20. CCT301 CAR-T Cell Therapy (Shanghai Sinobioway Sunterra Biotech)
15.4.5.20.1. Target Patient Population
15.4.5.20.2. Sales Forecast (USD Million)
15.4.5.20.3. Net Present Value (USD Million)
15.4.5.20.4. Value Creation Analysis

15.4.5.21. BinD19 (Shenzhen BinDeBio)
15.4.5.21.1. Target Patient Population
15.4.5.21.2. Sales Forecast (USD Million)
15.4.5.21.3. Net Present Value (USD Million)
15.4.5.21.4. Value Creation Analysis

15.4.5.22. CARCIK-CD19 (Formula Pharmaceuticals)
15.4.5.22.1. Target Patient Population
15.4.5.22.2. Sales Forecast (USD Million)
15.4.5.22.3. Net Present Value (USD Million)
15.4.5.22.4. Value Creation Analysis

15.4.5.23. EGFR CAR-T Cell Therapy (The Beijing Pregene Science and Technology)
15.4.5.23.1. Target Patient Population
15.4.5.23.2. Sales Forecast (USD Million)
15.4.5.23.3. Net Present Value (USD Million)
15.4.5.23.4. Value Creation Analysis

15.4.5.24. Anti-MUC1 CAR-T Cell Therapy (Guangzhou Anjie Biomedical Technology)
15.4.5.24.1. Target Patient Population
15.4.5.24.2. Sales Forecast (USD Million)
15.4.5.24.3. Net Present Value (USD Million)
15.4.5.24.4. Value Creation Analysis

15.4.5.25. PBCAR269A (Precision BioSciences and Servier)
15.4.5.25.1. Target Patient Population
15.4.5.25.2. Sales Forecast (USD Million)
15.4.5.25.3. Net Present Value (USD Million)
15.4.5.25.4. Value Creation Analysis

15.4.5.26. CD123 CAR-T cell Therapy (Chongqing Precision Biotechnology)
15.4.5.26.1. Target Patient Population
15.4.5.26.2. Sales Forecast (USD Million)
15.4.5.26.3. Net Present Value (USD Million)
15.4.5.26.4. Value Creation Analysis

15.4.5.27. BCMA CAR-T (Chongqing Precision Biotech)
15.4.5.27.1. Target Patient Population
15.4.5.27.2. Sales Forecast (USD Million)
15.4.5.27.3. Net Present Value (USD Million)
15.4.5.27.4. Value Creation Analysis

15.4.5.28. P-BCMA-101 (Poseida Therapeutics and California Institute for Regenerative Medicine)
15.4.5.28.1. Target Patient Population
15.4.5.28.2. Sales Forecast (USD Million)
15.4.5.28.3. Net Present Value (USD Million)
15.4.5.28.4. Value Creation Analysis

16. PROMOTIONAL ANALYSIS
16.1. Chapter Overview
16.2. Channels Used for Promotional Campaigns
16.3. Summary of Product Website Analysis
16.4. Summary of Patient Support Services and Informative Downloads

16.5. KYMRIAH®: Promotional Analysis
16.5.1. Drug Overview
16.5.2. Product Website Analysis
16.5.2.1. Messages for Healthcare Professionals
16.5.2.2. Messages for Patients
16.5.3. Patient Support Services and Informative Downloads
16.5.4. Other Promotional Activities
16.5.4.1. Presence in Conferences

16.6. YESCARTA®: Promotional Analysis
16.6.1. Drug Overview
16.6.2. Product Website Analysis
16.6.2.1. Messages for Healthcare Professionals
16.6.2.3. Messages for Patients
16.6.3. Patient Support Services and Informative Downloads
16.6.4. Other Promotional Activities
16.6.4.1. Presence in Conferences

17. COMPANY PROFILES
17.1. Chapter Overview
17.2. Autolus
17.3. bluebird bio
17.4. CARsgen Therapeutics
17.5. Celgene (A Bristol Myers Squibb Company)
17.6. Cellectis
17.7. Cellular Biomedicine Group
17.8. Innovative Cellular Therapeutics
17.9. Kite Pharma (A Gilead Sciences Company)
17.10. Kuur Therapeutics
17.11. Noile-Immune Biotech
17.12. Novartis
17.13. Shanghai Genechem
17.14. Sinobioway Cell Therapy
17.15. Takara Bio
17.16. Ziopharm Oncology

18. CONCLUDING REMARKS
18.1. Chapter Overview

19. EXECUTIVE INSIGHTS
19.1. Chapter Overview
19.2. Cell Therapies
19.2.1. Interview Transcript: Tim Oldham, Chief Executive Officer

19.3. Celyad
19.3.1. Interview Transcript: Vincent Brichard, Vice President, Immuno-Oncologys

19.4. Changhai Hospital
19.4.1. Interview Transcript: Xian-Bao Zhan, Professor of Medicine and Director, Department of Oncology

19.5. Glycostem Therapeutics
19.5.1. Interview Transcript: Troels Jordansen, Chief Executive Officer

19.6. Gracell Biotechnologies
19.6.1. Interview Transcript: Wei (William) Cao, Chief Executive Officer

19.7. Kite Pharma
19.7.1. Interview Transcript: Adrian Bot, Vice President, Scientific Affairs

19.8. Theravectys
19.8.1. Interview Transcript: Aino Kalervo, Competitive Intelligence Manager, Strategy & Business Development

19.9. TxCell
19.9.1. Interview Transcript: Miguel Forte, Chief Operating Officer

19.10. University of Colorado
19.10.1. Interview Transcript: Enkhtsetseg Purev, Assistant Professor of Medicine

19.11. Waisman Biomanufacturing
19.11.1. Interview Transcript: Brian Dattilo, Manager of Business Development

20. APPENDIX 1: TABULATED DATA

21. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List Of Figures

Figure 3.1 Pillars of Cancer Therapy
Figure 3.2 Differences between Active and Passive Immunotherapies
Figure 3.3 Differences between Specific and Non-Specific Immunotherapies
Figure 3.4 Strategies Employed for the Redirection of T-Cells
Figure 3.5 T-Cell Manufacturing: General Procedure
Figure 3.6 Historical Development of CAR-T cells
Figure 3.7 Structure of Chimeric Antigen Receptor
Figure 3.8 Chimeric Antigen Receptors: Structural Variations across Different Generations
Figure 3.9 CAR-T Cell Therapies: Development Process
Figure 3.10 Challenges Associated with CAR-T Cell Therapies
Figure 4.1 Social Media Analysis: Historical Trend on Twitter, January 2012-April 2019
Figure 4.2 Social Media Analysis: Trending Words / Phrases on Twitter
Figure 4.3 Social Media Analysis: Most Popular Drug Candidates on Twitter
Figure 4.4 Social Media Analysis: Most Prolific Authors on Twitter
Figure 4.5 Average Number of Likes, Re-tweets and Comments Related to CAR-T Cell Therapies
Figure 4.6 Social Media Analysis: Most Popular Indications and Target Antigen
Figure 5.1 CAR-T Cell Therapies: Distribution by Type of Developer
Figure 5.2 CAR-T Cell Therapies: Distribution by Phase of Development
Figure 5.3 CAR-T Cell Therapies: Distribution by Therapeutic Area
Figure 5.4 CAR-T Cell Therapies: Distribution by Popular Target Indications
Figure 5.5 CAR-T Cell Therapies: Distribution by Popular Target Antigens
Figure 5.6 CAR-T Cell Therapies: Distribution by Source of T-Cells
Figure 5.7 CAR-T Cell Therapies: Distribution by Route of Administration
Figure 5.8 CAR-T Cell Therapies: Distribution by Dose Frequency
Figure 5.9 CAR-T Cell Therapies: Distribution by Target Patient Segment
Figure 5.10 CAR-T Cell Therapies: Distribution by Type of Therapy
Figure 5.11 CAR-T Cell Therapies: Active Industry Players by Number of Therapies in Clinical Development
Figure 5.12 CAR-T Cell Therapies: Active Industry Players by Number of Therapies in Preclinical Development
Figure 5.13 CAR-T Cell Therapies: Active Non-Industry Players by Number of Therapies in Clinical Development
Figure 5.14 CAR-T Cell Therapies: Active Non-Industry Players by Number of Therapies in Preclinical Development
Figure 6.1 CAR-T Cell Therapies: Popular Targets in Hematological Malignancies
Figure 6.2 CAR-T Cell Therapies: Popular Targets in Solid Tumor
Figure 6.3 CAR-T Cell Therapies: Geographical Distribution of Key Opinion Leaders
Figure 6.4 CAR-T Cell Therapies: Prominent Key Opinion Leaders
Figure 6.5 CAR-Construction: Analysis by Generation of CAR-T Therapies
Figure 6.6 CAR-Construction: Analysis by Type of scFv Antibody used in CAR-T Therapies
Figure 6.7 CAR-Construction: Analysis by Type of Vector
Figure 6.8 CAR-Construction: Analysis by Type of Co-Stimulatory Domain(s)
Figure 7.1 CAR-T Cell Therapy Clinical Trials: Distribution by Trial Registration Year
Figure 7.2 CAR-T Cell Therapy Clinical Trials: Distribution by Year of Registration and Geography (Pre-2016 and 2016-2019)
Figure 8.1 Manufacturing of CD19 CAR-T Cells: Process Comparison
Figure 9.1 Leukemia: Classification
Figure 9.2 Leukemia: Global Epidemiological Distribution
Figure 9.3 Lymphoma: Global Epidemiological Distribution
Figure 9.4 Multiple Myeloma: Global Epidemiological Distribution
Figure 9.5 Melanoma: Global Epidemiological Distribution
Figure 9.6 Lung Cancer: Classification
Figure 9.7 Lung Cancer: Global Epidemiological Distribution
Figure 9.8 Pancreatic Cancer: Global Epidemiological Distribution
Figure 9.9 Liver Cancer: Global Epidemiological Distribution
Figure 9.10 Breast Cancer: Global Epidemiological Distribution
Figure 9.11 Ovarian Cancer: Global Epidemiological Distribution
Figure 9.12 Bladder Cancer: Global Epidemiological Distribution
Figure 9.13 Kidney Cancer: Global Epidemiological Distribution
Figure 10.1 Genome Editing Technologies: Applications
Figure 10.2 Genome Editing: Emerging Technology Platforms Used in CAR-T Cell Therapies
Figure 10.3 Competitiveness Analysis: Gene Editing Platforms
Figure 10.4 CAR-T Cell Therapies: Key Technologies to Enhance Features / Characteristics
Figure 10.5 Cellectis: Properties of Enhanced T-Cell Platform
Figure 10.6 Cellectis: Allogenic CAR-T Platform, Comparison with Autologous CAR-T Platform
Figure 11.1 Partnerships and Collaborations: Cumulative Year-Wise Trend, 2005-2020
Figure 11.2 Partnerships and Collaborations: Year-Wise Distribution by Type of Partner, Pre-2013-2020
Figure 11.3 Partnerships and Collaborations: Distribution by Type of Partnership
Figure 11.4 Partnerships and Collaborations: Distribution by Type of Partnership, Pre-2015 and 2015-2020
Figure 11.5 Partnerships and Collaborations: Distribution by Individual Products
Figure 11.6 Partnerships and Collaborations: Most Active Industry Players
Figure 11.7 Partnerships and Collaborations: Most Active Non-Industry Players
Figure 11.8 Partnerships and Collaborations: Most Active Contract Manufacturers
Figure 11.9 Partnerships and Collaborations: Intercontinental and Intracontinental Manufacturing Agreements
Figure 11.10 Partnerships and Collaborations: Regional Distribution
Figure 11.11 Partnerships and Collaborations: Intercontinental and Intracontinental Distribution
Figure 12.1 Funding and Investment Analysis: Cumulative Year-wise Trend of Funding Instances, Pre 2013-2020 (till October)
Figure 12.2 Funding and Investment Analysis: Cumulative Distribution of Amount Invested, Pre 2013-2020 (USD Million)
Figure 12.3 Funding and Investment Analysis: Distribution of Instances by Type of Funding
Figure 12.4 Funding and Investment Analysis: Distribution of Amount Invested by Type of Funding (USD Million)
Figure 12.5 Most Active Players: Distribution by Number of Funding Instances
Figure 12.6 Funding and Investment: Distribution by Types of Investor
Figure 12.7 Most Active Players: Distribution by Number of Instances
Figure 12.8 Funding and Investment Analysis: Distribution by Geography
Figure 12.9 Funding and Investment Analysis: Distribution of Amount Invested across Different Countries (USD Million)
Figure 13.1 Steps in Cell Therapy Manufacturing
Figure 13.2 Centralized Manufacturing: Process Model
Figure 13.3 Decentralized Manufacturing: Process Model
Figure 13.4 Cell Therapy Manufacturing: Types of Manufacturers
Figure 13.5 Cell Therapy Manufacturing: Challenges and Drivers
Figure 13.6 Cell Therapies: Potency as Critical Quality Attribute
Figure 13.7 Cell Therapy Manufacturing: Supply Chain Model
Figure 13.8 Cell Therapy Manufacturing: Supply Chain Risk Assessment Considerations
Figure 14.1 Targeted Therapies: Pricing Model Based on Patient Segment
Figure 15.1 Overall CAR-T Cell Therapies Market, 2021-2030 (USD Billion)
Figure 15.2 CAR-T Cell Therapies Market: Distribution by Target Indication (USD Billion)
Figure 15.3 CAR-T Cell Therapies Market: Distribution by Target Antigen (USD Billion)
Figure 15.4 CAR-T Cell Therapies Market: Key Players (USD Billion)
Figure 15.5 CAR-T Cell Therapies Market: Distribution by Target Geography (USD Billion)
Figure 15.6 KYMRIAH® (Novartis): Current Status of Development
Figure 15.7 KYMRIAH® (Novartis) Sales Forecast, till 2030 (USD Million)
Figure 15.8 YESCARTA® (Gilead Sciences): Current Status of Development
Figure 15.9 YESCARTA® (Gilead Sciences) Sales Forecast, till 2030 (USD Million)
Figure 15.10 TECARTUS® (Gilead Sciences): Current Status of Development
Figure 15.11 TECARTUS®: (Gilead Sciences) Sales Forecast, till 2030 (USD Million)
Figure 15.12 BREYANZI® / Lisocabtagene Maraleucel / JCAR017JCAR017 (Bristol Myers Squibb / Juno Therapeutics): Current Status of Development
Figure 15.13 BREYANZI® / Lisocabtagene Maraleucel / JCAR017JCAR017 (Bristol Myers Squibb / Juno Therapeutics) Sales Forecast, till 2030 (USD Million)
Figure 15.14 Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb): Current Statusof Development
Figure 15.15 Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb) Sales Forecast, till 2030 (USD Million)
Figure 15.16 Ciltacabtagene Autoleucel / LCAR-B38M (Nanjing Legend Biotech /Janssen): Current Status of Development
Figure 15.17 Ciltacabtagene Autoleucel / LCAR-B38M (Nanjing Legend Biotech / Janssen) Sales Forecast, till 2030 (USD Million)
Figure 15.18 MB-CART19.1 (Miltenyi Biotec): Current Status of Development
Figure 15.19 MB-CART19.1 (Miltenyi Biotec) Sales Forecast, till 2030 (USD Million)
Figure 15.20 Descartes-11 (Cartesian Therapeutics): Current Status of Development
Figure 15.21 Descartes-11 (Cartesian Therapeutics) Sales Forecast, till 2030 (USD Million)
Figure 15.22 CD19 CAR-T (Sinobioway Cell Therapy): Current Status of Development
Figure 15.23 CD19 CAR-T (Sinobioway Cell Therapy) Sales Forecast, till 2030 (USD Million)
Figure 15.24 AUTO1 (Autolus): Current Status of Development
Figure 15.25 AUTO1 (Autolus) Sales Forecast, till 2030 (USD Million)
Figure 15.26 AUTO3 (Autolus): Current Status of Development
Figure 15.27 AUTO3 (Autolus) Sales Forecast, till 2030 (USD Million)
Figure 15.28 GPC3 CAR-T (Shanghai GeneChem): Current Status of Development
Figure 15.29 GPC3 CAR-T (Shanghai GeneChem) Sales Forecast, till 2030 (USD Million)
Figure 15.30 BCMA CAR-T (The Pregene (ShenZhen) Biotechnology): Current Status of Development
Figure 15.31 BCMA CAR-T (The Pregene (ShenZhen) Biotechnology) Sales Forecast, till 2030(USD Million)
Figure 15.32 CD19 CAR-T (The Pregene (ShenZhen) Biotechnology): Current Status ofDevelopment
Figure 15.33 CD19 CAR-T (The Pregene (ShenZhen) Biotechnology) Sales Forecast, till 2030 (USD Million)
Figure 15.34 CD19 CAR-T (Shanghai Bioray Laboratory): Current Status of Development
Figure 15.35 CD19 CAR-T (Shanghai Bioray Laboratory) Sales Forecast, till 2030 (USD Million)
Figure 15.36 Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicine Technology): Current Status of Development
Figure 15.37 Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicine Technology, Sales Forecast, till 2030 (USD Million)
Figure 15.38 PCAR-019 (PersonGen BioTherapeutics): Current Status of Development
Figure 15.39 PCAR-019 (PersonGen BioTherapeutics) Sales Forecast, till 2030 (USD Million)
Figure 15.40 TBI-1501 (Takara Bio): Current Status of Development
Figure 15.41 TBI-1501 (Takara Bio) Sales Forecast, till 2030 (USD Million)
Figure 15.42 IM19 CAR-T (Beijing Immunochina Medical Science & Technology): Current Status of Development
Figure 15.43 IM19 CAR-T (Beijing Immunochina Medical Science & Technology) Sales Forecast, till 2030 (USD Million)
Figure 15.44 CCT301 CAR-T (Shanghai Sinobioway Sunterra Biotech): Current Status of Development
Figure 15.45 CCT301 CAR-T (Shanghai Sinobioway Sunterra Biotech) Sales Forecast, till 2030 (USD Million)
Figure 15.46 BinD19 (Shenzhen BinDeBio): Current Status of Development
Figure 15.47 BinD19 (Shenzhen BinDeBio) Sales Forecast, till 2030 (USD Million)
Figure 15.48 CARCIK-CD19 (Formula Pharmaceuticals): Current Status of Development
Figure 15.49 CARCIK-CD19 (Formula Pharmaceuticals) Sales Forecast, till 2030 (USD Million)
Figure 15.50 EGFR CAR-T (The Beijing Pregene Science and Technology): Current Status of Development
Figure 15.51 EGFR CAR-T (The Beijing Pregene Science and Technology) Sales Forecast, till 2030 (USD Million)
Figure 15.52 Anti-MUC1 CAR-T Cell Therapy (Guangzhou Anjie Biomedical Technology): Current Status of Development
Figure 15.53 Anti-MUC1 CAR-T Cell Therapy (Guangzhou Anjie Biomedical Technology) Sales Forecast, till 2030 (USD Million)
Figure 15.54 PBCAR269A (Precision BioSciences and Servier): Current Status of Development
Figure 15.55 PBCAR269A (Precision BioSciences and Servier) Sales Forecast, till 2030 (USD Million)
Figure 15.56 CD123 CAR-T cells (Chongqing Precision Biotechnology): Current Status of Development
Figure 15.57 CD123 CAR-T cells (Chongqing Precision Biotechnology) Sales Forecast, till 2030 (USD Million)
Figure 15.58 BCMA CAR-T (Chongqing Precision Biotech): Current Status of Development
Figure 15.59 BCMA CAR-T (Chongqing Precision Biotech) Sales Forecast, till 2030 (USD Million)
Figure 15.60 P-BCMA-101 (Poseida Therapeutics / California Institute for RegenerativeMedicine): Current Status of Development
Figure 15.61 P-BCMA-101 (Poseida Therapeutics and California Institute for Regenerative Medicine) Sales Forecast, till 2030 (USD Million)
Figure 16.1 Channels Used for Promotional Campaigns
Figure 16.2 Promotional / Marketing Strategy: Product Website Analysis
Figure 16.3 Promotional / Marketing Strategy: Patient Support Services and Informative Downloads
Figure 16.4 Product Website Analysis: KYMRIAH®, Messages for Healthcare Professionals
Figure 16.5 Product Website Analysis: KYMRIAH®, Messages for Patients
Figure 16.6 Product Website Analysis: KYMRIAH®, Patient Support Program
Figure 16.7 KYMRIAH®, Presence in Conferences
Figure 16.8 Product Website Analysis: YESCARTA®, Messages for Healthcare Professionals
Figure 16.9 Product Website Analysis: YESCARTA®, Messages for Patients
Figure 16.10 Product Website Analysis: YESCARTA®, Kite Konnect
Figure 16.11 Product Website Analysis: YESCARTA®, Platform for Reporting Adverse Events  / Products Complaints and Requesting Medical Information
Figure 16.12 YESCARTA®, Presence in Conferences
Figure 18.1 Concluding Remarks: Overall Market Landscape
Figure 18.2 Concluding Remarks: Clinical Trial Analysis
Figure 18.3 Concluding Remarks: Partnerships & Collaborations and Funding and Investment Analysis
Figure 18.4 Concluding Remarks: Market Forecast

List Of Tables

Table 3.1 Types of Immunotherapies and Affiliated Mechanisms of Action
Table 3.2 FDA Approved Antibody based Cancer Therapeutics
Table 3.3 Key Characteristics of CAR-T Cells
Table 3.4 Comparison of First and Second-Generation CAR-Ts
Table 3.5 CD19 CAR-T Cells: Preclinical Results
Table 3.6 Other Targets under Clinical / Preclinical Studies for CAR-T Cell Therapies
Table 5.1 CAR-T Cell Therapies: Clinical Pipeline
Table 5.2 CAR-T Cell Therapies: Preclinical Pipeline
Table 6.1 CD19 CAR-T Cell Therapies: Competitive Landscape
Table 6.2 CD19 CAR-T Cell Therapies: Clinical Outcomes
Table 6.3 BCMA CAR-T Cell Therapies: Competitive Landscape
Table 6.4 BCMA CAR-T Cell Therapies: Clinical Outcomes
Table 6.5 Meso CAR-T Cell Therapies: Competitive Landscape
Table 6.6 Meso CAR-T Cell Therapies: Clinical Outcomes
Table 6.7 GD2 CAR-T Cell Therapies: Competitive Landscape
Table 6.8 GD2 CAR-T Cell Therapies: Clinical Outcomes
Table 6.9 CAR-T Cell Therapies: Principle Investigators
Table 6.10 CAR-T Therapies: Information on Constructs of Clinical Candidates
Table 7.1 CAR-T Cell Therapies: List of Clinical Trials
Table 7.2 Advanced Phase CAR-T Cell Therapies in China
Table 8.1 KYMRIAH®: Clinical Studies
Table 8.2 KYMRIAH®: Clinical Trial Endpoints (ALL)
Table 8.3 KYMRIAH®: Clinical Trial Endpoints (CLL / NHL / FL / MCL / CNSL)
Table 8.4 YESCARTA®: Clinical Studies
Table 8.5 YESCARTA®: Clinical Trial Endpoints
Table 8.6 TECARTUS® / Brexucabtagene Autoleucel: Clinical Studies
Table 8.7 TECARTUS® / Brexucabtagene Autoleucel: Clinical Trial Endpoints
Table 8.8 JCAR Series: Molecules in Clinical Phase of Development
Table 8.9 JCAR: CAR-T Design
Table 8.10 JCAR014: Clinical Studies
Table 8.11 JCAR017: Clinical Studies
Table 8.12 JCAR018: Clinical Studies
Table 8.13 JCAR020: Clinical Studies
Table 8.14 JCAR023: Clinical Studies
Table 8.15 JCAR024: Clinical Studies
Table 8.16 JCARH125: Clinical Studies
Table 8.17 JCAR Series: Clinical Trial Endpoints (Phase I/II / Phase II / Phase III)
Table 8.18 JCAR Series: Clinical Trial Endpoints (Phase I)
Table 8.19 JCAR: Dosage Regimen
Table 8.20 Idecabtagene Vicleucel / bb2121: Clinical Studies
Table 8.21 Idecabtagene Vicleucel / bb2121: Clinical Trial Endpoints
Table 8.22 Ciltacabtagene Autoleucel / LCAR-B38M / JUN-68284528: Clinical Studies
Table 8.23 Ciltacabtagene Autoleucel / LCAR-B38M / JUN-68284528: Clinical Trial Endpoints
Table 8.24 TBI-1501: Clinical Studies
Table 8.25 TBI-1501: Clinical Trial Endpoints
Table 8.26 TBI-1501: Dosage Regimen
Table 8.27 AUTO1: Clinical Studies
Table 8.28 AUTO3: Clinical Studies
Table 8.29 AUTO4: Clinical Studies
Table 8.30 Autolus’s Next Generation CAR-T Cell Therapies: Clinical Trial Endpoints
Table 8.31 Sinobioway Cell Therapy’s CD19 CAR-T Therapy: Clinical Studies
Table 8.32 Sinobioway Cell Therapy’s EPCAM CAR-T Therapy: Clinical Studies
Table 8.33 Sinobioway Cell Therapy’s Targeting CAR-T Cell Therapies: Clinical Trial Endpoints
Table 8.34 Phase I/II or Phase II CAR-T Cell Therapies from the Industry Players
Table 9.1 Comparison of Hodgkin’s and Non-Hodgkin’s Lymphoma
Table 9.2 Leukemia: List of Marketed Targeted Therapeutics
Table 9.3 Lymphoma: List of Marketed Targeted Therapeutics
Table 9.4 CAR-T Cell Therapies: Targets under Investigation for Leukemia
Table 9.5 CAR-T Cell Therapies: Targets under Investigation for Lymphoma
Table 9.6 Multiple Myeloma: List of Marketed Targeted Therapeutics
Table 9.7 CAR-T Cell Therapies: Targets under Investigation for Multiple Myeloma
Table 9.8 Melanoma: List of Marketed Targeted Therapeutics
Table 9.9 CAR-T Cell Therapies: Targets under Investigation for Melanoma
Table 9.10 Lung Cancer: List of Marketed Targeted Therapeutics
Table 9.11 CAR-T Cell Therapies: Targets under Investigation for Lung Cancer
Table 9.12 Pancreatic Cancer: List of Marketed Targeted Therapeutics
Table 9.13 CAR-T Cell Therapies: Targets under Investigation for Pancreatic Cancer
Table 9.14 Liver Cancer: List of Marketed Targeted Therapeutics
Table 9.15 CAR-T Cell Therapies: Targets under Investigation for Liver Cancer
Table 9.16 Breast Cancer: List of Marketed Targeted Therapeutics
Table 9.17 CAR-T Cell Therapies: Targets under Investigation for Breast Cancer
Table 9.18 Ovarian Cancer: List of Marketed Targeted Therapeutics
Table 9.19 CAR-T Cell Therapies: Targets under Investigation for Ovarian Cancer
Table 9.20 Bladder Cancer: List of Marketed Targeted Therapeutics
Table 9.21 Renal Cell Carcinoma: List of Marketed Targeted Therapeutics
Table 10.1 Editas Medicine: CRISPR / Cas9 Technology, Research Publications
Table 10.2 Editas Medicine: Funding Instances
Table 10.3 Editas Medicine: Partnerships & Collaborations
Table 10.4 Intellia Therapeutics: CRISPR / Cas9 Technology, Research Publications
Table 10.5 Intellia Therapeutics: Funding Instances
Table 10.6 Intellia Therapeutics: Collaborations
Table 10.7 CRISPR Therapeutics: CRISPR / Cas9 Technology, Research Publications
Table 10.8 CRISPR Therapeutics: Funding Instances
Table 10.9 CRISPR Therapeutics: Partnerships & Collaborations
Table 10.10 Beam Therapeutics: Funding Instances
Table 10.11 Beam Therapeutics: Collaborations
Table 10.12 Gracell Biotechnologies: Funding Instances
Table 10.13 Cellectis: Funding Instances
Table 10.14 Cellectis: Partnerships & Collaborations
Table 10.15 bluebird bio: megaTAL Technology, Research Publications
Table 10.16 bluebird bio: Funding Instances
Table 10.17 bluebird bio: Partnerships & Collaborations
Table 10.18 Sangamo Therapeutics: Funding Instances
Table 10.19 Sangamo Therapeutics: Partnerships & Collaborations
Table 10.20 Cogent Biosciences: Funding Instances
Table 10.21 Cogent Biosciences: Partnerships & Collaborations
Table 10.22 Celyad Oncology: Funding Instances
Table 10.23 Celyad Oncology: Partnerships & Collaborations
Table 10.24 Glycostem: Funding Instances
Table 10.25 Glycostem: Partnerships & Collaborations
Table 10.26 Intrexon: Funding Instances
Table 10.27 Intrexon: Collaborations
Table 10.28 Bellicum Pharmaceuticals: Key Switch Technologies
Table 10.29 Bellicum Pharmaceuticals: Switch Technologies, Research Publications
Table 10.30 Bellicum Pharmaceuticals: Funding Instances
Table 10.31 Bellicum Pharmaceuticals: Collaborations
Table 10.32 Theravectys: Funding Instances
Table 10.33 Technologies For CAR-T Safety Enhancement
Table 10.34 Formula Pharmaceuticals: Collaborations
Table 11.1 CAR-T Cell Therapy Market: List of Partnerships and Collaborations, 2005-2020 (till October)
Table 12.1 CAR-T Cell Therapies: Funding and Investments, 2000-2020 (till October)
Table 12.2 CAR-T Cell Therapies Summary of Investments
Table 13.1 Assessment Strategies for Different Manufacturing Processes
Table 13.2 Advantages and Disadvantages of Centralized and Decentralized Manufacturing Models
Table 13.3 Cell Therapy Manufacturing: Companies with In-house Capabilities
Table 13.4 Cell Therapy Manufacturing: Contract Manufacturers
Table 14.1 Price of Marketed Gene / Cell Therapies
Table 14.2 Price of Marketed Targeted Drugs
Table 14.3 CAR-T Cell Therapies: Expert Opinions on Pricing
Table 14.4 CAR-T Cell Therapies: Reimbursement Landscape
Table 15.1 CAR-T Cell Therapies: List of Forecasted Molecules
Table 15.2 KYMRIAH® (Novartis): Net Present Value (USD Million)
Table 15.3 KYMRIAH® (Novartis): Value Creation Analysis (USD Million)
Table 15.4 YESCARTA® (Gilead Sciences): Net Present Value (USD Million)
Table 15.5 YESCARTA® (Gilead Sciences): Value Creation Analysis (USD Million)
Table 15.6 TECARTUS®: (Gilead Sciences): Net Present Value (USD Million)
Table 15.7 TECARTUS®: (Gilead Sciences): Value Creation Analysis (USD Million)
Table 15.8 BREYANZI® / Lisocabtagene Maraleucel / JCAR017JCAR017 (Bristol Myers Squibb / Juno Therapeutics): Net Present Value (USD Million)
Table 15.9 BREYANZI® / Lisocabtagene Maraleucel / JCAR017JCAR017 (Bristol Myers Squibb / Juno Therapeutics): Value Creation Analysis (USD Million)
Table 15.10 Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb): Net Present Value (USD Million)
Table 15.11 Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb): Value Creation Analysis (USD Million)
Table 15.12 Ciltacabtagene Autoleucel / LCAR-B38M (Nanjing Legend Biotech / Janssen): Net Present Value (USD Million)
Table 15.13 Ciltacabtagene Autoleucel / LCAR-B38M (Nanjing Legend Biotech/ Janssen): Value Creation Analysis (USD Million)
Table 15.14 MB-CART19.1 (Miltenyi Biotec): Net Present Value (USD Million)
Table 15.15 MB-CART19.1 (Miltenyi Biotec): Value Creation Analysis (USD Million)
Table 15.16 Descartes-11 (Cartesian Therapeutics): Net Present Value (USD Million)
Table 15.17 Descartes-11 (Cartesian Therapeutics): Value Creation Analysis (USD Million)
Table 15.18 CD19 CAR-T (Sinobioway Cell Therapy): Net Present Value (USD Million)
Table 15.19 CD19 CAR-T (Sinobioway Cell Therapy): Value Creation Analysis (USD Million)
Table 15.20 AUTO1 (Autolus): Net Present Value (USD Million)
Table 15.21 AUTO1 (Autolus): Value Creation Analysis (USD Million)
Table 15.22 AUTO3 (Autolus): Net Present Value (USD Million)
Table 15.23 AUTO3 (Autolus): Value Creation Analysis (USD Million)
Table 15.24 GPC3 CAR-T (Shanghai Genechem): Net Present Value (USD Million)
Table 15.25 GPC3 CAR-T (Shanghai Genechem): Value Creation Analysis (USD Million)
Table 15.26 BCMA CAR-T (The Pregene (ShenZhen) Biotechnology): Net Present Value (USD Million)
Table 15.27 BCMA CAR-T (The Pregene (ShenZhen) Biotechnology): Value Creation Analysis (USD Million)
Table 15.28 CD19 CAR-T (The Pregene (ShenZhen) Biotechnology): Net Present Value (USD Million)
Table 15.29 CD19 CAR-T (The Pregene (ShenZhen) Biotechnology): Value Creation Analysis (USD Million)
Table 15.30 CD19 CAR-T (Shanghai Bioray Laboratory): Net Present Value (USD Million)
Table 15.31 CD19 CAR-T (Shanghai Bioray Laboratory): Value Creation Analysis (USD Million)
Table 15.32 Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicine Technology): Net Present Value (USD Million)
Table 15.33 Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicineTechnology): Value Creation Analysis (USD Million)
Table 15.34 PCAR-019 (PersonGen BioTherapeutics): Net Present Value (USD Million)
Table 15.35 PCAR-019 (PersonGen BioTherapeutics): Value Creation Analysis (USDMillion)
Table 15.36 TBI-1501 (Takara Bio): Net Present Value (USD Million)
Table 15.37 TBI-1501 (Takara Bio): Value Creation Analysis (USD Million)
Table 15.38 IM19 CAR-T T (Beijing Immunochina Medical Science & Technology): Net Present Value (USD Million)
Table 15.39 IM19 CAR-T T (Beijing Immunochina Medical Science & Technology): Value Creation Analysis (USD Million)
Table 15.40 CCT301 CAR-T (Shanghai Sinobioway Sunterra Biotech): Net Present Value (USD
Table 15.41 CCT301 CAR-T (Shanghai Sinobioway Sunterra Biotech): Value Creation Analysis (USD Million)
Table 15.42 BinD19 (Shenzhen BinDeBio): Net Present Value (USD Million)
Table 15.43 BinD19 (Shenzhen BinDeBio): Value Creation Analysis (USD Million)
Table 15.44 CARCIK-CD19 (Formula Pharmaceuticals): Net Present Value (USD Million)
Table 15.45 CARCIK-CD19 (Formula Pharmaceuticals): Value Creation Analysis (USD Million)
Table 15.46 EGFR CAR-T (The Beijing Pregene Science and Technology): Net Present Value (USD Million)
Table 15.47 EGFR CAR-T (The Beijing Pregene Science and Technology): Value Creation Analysis (USD Million)
Table 15.48 ANTI-MUC1 CAR-T Cell Therapy (Guangzhou Anjie Biomedical Technology): Net Present Value (USD Million)
Table 15.49 ANTI-MUC1 CAR-T Cell Therapy (Guangzhou Anjie Biomedical Technology): Value Creation Analysis (USD Million)
Table 15.50 PBCAR269A (Precision BioSciences and Servier): Net Present Value (USD Million)
Table 15.51 PBCAR269A (Precision BioSciences and Servier): Value Creation Analysis (USD Million)
Table 15.52 CD123 CAR-T cells (Chongqing Precision Biotechnology): Net Present Value (USD Million)
Table 15.53 CD123 CAR-T cells (Chongqing Precision Biotechnology): Value Creation Analysis (USD Million)
Table 15.54 BCMA CAR-T (Chongqing Precision Biotech): Net Present Value (USD Million)
Table 15.55 BCMA CAR-T (Chongqing Precision Biotech): Value Creation Analysis (USD Million)
Table 15.56 P-BCMA-101 (Poseida Therapeutics / California Institute for RegenerativeMedicine): Net Present Value (USD Million)
Table 15.57 P-BCMA-101 (Poseida Therapeutics / California Institute for RegenerativeMedicine): Value Creation Analysis (USD Million)
Table 16.1 KYMRIAH®: Drug Overview
Table 16.2 YESCARTA®: Drug Overview
Table 17.1 Autolus: Company Profile
Table 17.2 bluebird bio: Company Profile
Table 17.3 CARsgen Therapeutics: Company Profile
Table 17.4 Celgene: Company Profile
Table 17.5 Cellectis: Company Profile
Table 17.6 Cellular Biomedicine Group: Company Profile
Table 17.7 Innovative Cellular Therapeutics: Company Profile
Table 17.8 Kite Pharma: Company Profile
Table 17.9 Kuur Therapeutics: Company Profile
Table 17.10 Noile-Immune Biotech: Company Profile
Table 17.11 Novartis: Company Profile
Table 17.12 Shanghai Genechem: Company Profile
Table 17.13 Sinobioway Cell Therapy: Company Profile
Table 17.14 Takara Bio: Company Profile
Table 17.15 Ziopharm Oncology: Company Profile
Table 20.1 CAR-T Cell Therapies: Distribution by Type of Developer
Table 20.2 CAR-T Cell Therapies: Distribution by Phase of Development
Table 20.3 CAR-T Cell Therapies: Distribution by Target Therapeutic Area
Table 20.4 CAR-T Cell Therapies: Distribution by Popular Target Indications
Table 20.5 CAR-T Cell Therapies: Distribution by Popular Target Antigen
Table 20.6 CAR-T Cell Therapies: Distribution by Source of T-Cells
Table 20.7 CAR-T Cell Therapies: Distribution by Route of Administration
Table 20.8 CAR-T Cell Therapies: Distribution by Dose Frequency
Table 20.9 CAR-T Cell Therapies: Distribution by Target Patient Segment
Table 20.10 CAR-T Cell Therapies: Distribution by Type of Therapy
Table 20.11 CAR-T Cell Therapies: Active Industry Players by Number of Therapies in Clinical Phase of Development
Table 20.12 CAR-T Cell Therapies: Active Industry Players by Number of Therapies in Preclinical Development
Table 20.13 CAR-T Cell Therapies: Active Non-Industry Players by Number of Therapies in Clinical Development
Table 20.14 CAR-T Cell Therapies: Active Non-Industry Players by Number of Therapies in Preclinical Development
Table 20.15 CAR-T Cell Therapies: Popular Targets in Hematological Cancer
Table 20.16 CAR-T Cell Therapies: Popular Targets in Solid Tumor
Table 20.17 CAR-Construction: Analysis by Generation of CAR-T Therapies
Table 20.18 CAR-Construction: Analysis by Type of scFv Antibody used in CAR-T Therapies
Table 20.19 CAR-Construction: Analysis by Type of Vector
Table 20.20 CAR-Construction: Analysis by Type of Co-Stimulatory Domain(s)
Table 20.21 CAR-T Cell Therapy Clinical Trials: Distribution by Trial Registration Year
Table 20.22 CAR-T Cell Therapy Clinical Trials: Distribution by Number of Clinical Trials and Geography (Pre-2016 and 2019)
Table 20.23 Partnerships and Collaborations: Cumulative Year-Wise Trend, 2005-2020
Table 20.24 Partnerships and Collaborations: Distribution by Type of Partnership
Table 20.25 Partnerships and Collaborations: Distribution by Type of Partnership, Pre-2015 and 2015-2020
Table 20.26 Partnerships and Collaborations: Distribution by Type of Partner
Table 20.27 Partnerships and Collaborations: Distribution by Individual Products
Table 20.28 Partnerships and Collaborations: Most Active Industry Players
Table 20.29 Partnerships and Collaborations: Most Active Non-Industry Players
Table 20.30 Partnerships and Collaborations: Most Active Contract Manufacturers
Table 20.31 Partnerships and Collaborations: Intercontinental and Intracontinental Manufacturing Agreements
Table 20.32 Partnerships and Collaborations: Regional Distribution
Table 20.33 Partnerships and Collaborations: Intercontinental and Intracontinental Distribution
Table 20.34 Funding and Investment Analysis: Cumulative Year-wise Trend of Funding Instances, Pre 2013-2020 (till October)
Table 20.35 Funding and Investment Analysis: Distribution by Cumulative Amount Invested, Pre 2013-2020 (USD Million)
Table 20.36 Funding and Investment Analysis: Distribution of Instances by Type of Funding
Table 20.37 Funding and Investment Analysis: Distribution of Total Amount Invested by Type of Funding (USD Million)
Table 20.38 Most Active Players: Distribution by Number of Instances
Table 20.39 Funding and Investments: Distribution by Types of Investor
Table 20.40 Most Active Players: Distribution by Number of Instances
Table 20.41 Funding and Investment Analysis: Distribution by Geography
Table 20.42 Funding and Investment Analysis: Distribution of Amount Invested across Different Countries (USD Million)
Table 20.43 Overall CAR-T Cell Therapies Market, 2021-2030, Conservative, Base and Optimistic Scenarios (USD Billion)
Table 20.44 CAR-T Cell Therapies Market: Distribution by Target Indication(s), 2025 and 2030 (USD Billion)
Table 20.45 CAR-T Cell Therapies Market: Distribution by Target Antigen(s), 2025 and 2030 (USD Billion)
Table 20.46 CAR-T Cell Therapies Market: Key Players, 2025 and 2030 (USD Billion)
Table 20.47 CAR-T Cell Therapies Market: Distribution by Geography, 2025 and 2030 (USD Billion)
Table 20.48 KYMRIAH® (Novartis) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.49 YESCARTA® (Gilead Sciences) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.50 TECARTUS® (Gilead Sciences) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.51 Idecabtagene Vicleucel / bb2121 (bluebird bio / Bristol Myers Squibb) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.52 Ciltacabtagene Autoleucel / LCAR-B38M CAR-T (Nanjing Legend Biotech / Janssen) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.53 JCAR017 (Juno Therapeutics / Celgene / WuXi AppTec) Sales Forecast, Conservative, 
Table 20.54 MB-CART19.1 (Miltenyi Biotec) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.55 Descartes-11 (Cartesian Therapeutics) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.56 CD19 CAR-T (Sinobioway Cell Therapy) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.57 AUTO1 (Autolus) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.58 AUTO3 (Autolus) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.59 GPC3 CAR-T (Shanghai GeneChem) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.60 BCMA CAR-T (The Pregene (ShenZhen) Biotechnology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.61 CD19 CAR-T (The Pregene (ShenZhen) Biotechnology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.62 CD19 CAR-T (Shanghai Bioray Laboratory) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.63 Humanized CD19 CAR-T (Shanghai Unicar-Therapy Bio-medicine Technology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.64 PCAR-019 (PersonGen BioTherapeutics) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.65 TBI-1501 (Takara Bio) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.66 IM19 CAR-T (Beijing Immunochina Medical Science & Technology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.67 CCT301 CAR-T (Shanghai Sinobioway Sunterra Biotech) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.68 BinD19 (Shenzhen BinDeBio) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.69 CARCIK-CD19 (Formula Pharmaceuticals) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.70 EGFR CAR-T (The Beijing Pregene Science and Technology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.71 Anti-MUC1 CAR-T (Guangzhou Anjie Biomedical Technology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.72 PBCAR269A (Precision BioSciences) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.73 CD123 CAR-T Cells (Chongqing Precision Biotechnology) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.74 BCMA CAR-T (Chongqing Precision Biotech) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)
Table 20.75 P-BCMA-101 (Poseida Therapeutics) Sales Forecast, Conservative, Base and Optimistic Scenarios, till 2030 (USD Million)

List Of Companies

The following companies / institutes / government bodies and organizations have been mentioned in this report.

  1. 3P Biopharmaceuticals
  2. AbbVie
  3. AbCellera 
  4. AbCheck
  5. AbClon
  6. Abeona Therapeutics
  7. Abzena
  8. Academy of Military Medical Sciences (AMMS)
  9. Acıbadem Altunizade Hospital
  10. Acibadem University
  11. ACROBiosystems
  12. Adaptimmune
  13. Adicet Bio
  14. Adimab
  15. Advanced Cell Therapy Laboratory (ACTL)
  16. Advent Bioservices
  17. Aeon Biotherapeutics
  18. Affiliated Hospital of Jiangnan University
  19. Affiliated Hospital to Academy of Military Medical Sciences
  20. AffyImmune Therapeutics
  21. AgenTus Therapeutics
  22. Agilent Technologies
  23. Agreen Biotech 
  24. Alberta Cell Therapy Manufacturing (ACTM)
  25. Alexandria Real Estate Equities
  26. Allele Biotechnology and Pharmaceuticals
  27. Allife Medicine 
  28. Allogene Therapeutics
  29. Altor Bioscience
  30. Amgen
  31. Angel Biotechnology
  32. Anhui Anke Biotechnology 
  33. Anhui Provincial Hospital
  34. ANTAGENE
  35. Anterogen
  36. Arbele
  37. Argos Therapeutics
  38. Artiva Biotherapeutics 
  39. Aspire Health Science
  40. Astellas Pharma
  41. Astero Bio
  42. Atara Biotherapeutics
  43. Atossa Therapeutics
  44. Aurora Biopharma
  45. Autolus
  46. Avacta
  47. Avalon GloboCare
  48. Bambino Gesù Hospital and Research Institute
  49. Baxalta
  50. Baylor College of Medicine
  51. Be The Match BioTherapies
  52. Beam Therapeutics
  53. Beijing 302 Hospital
  54. Beijing Biohealthcare Biotechnology
  55. Beijing Boren Hospital
  56. Beijing Cancer Hospital
  57. Beijing Children's Hospital
  58. Beijing Doing Biomedical Technology
  59. Beijing HuiNengAn Biotech
  60. Beijing Immunochina Medical Science & Technology
  61. Beijing Lu Daopei Hospital
  62. Beijing Mario Biotech
  63. Beijing Sanbo Brain Hospital
  64. Beijing Sanwater Biological Technology
  65. Beijing Tsinghua Chang Gung Hospital
  66. Beijing Yimiao Shenzhou Pharmaceutical
  67. Bellicum Pharmaceuticals
  68. Beth Israel Deaconess Medical Center (BIDMC)
  69. Bio Elpida
  70. BioAtla
  71. BioCardia
  72. Bioceltech Therapeutics
  73. Bio-Gene Technology
  74. Bioinova
  75. BioLife Solutions
  76. Biological & Cellular GMP Manufacturing Facility
  77. BioNTech
  78. BioRestorative Therapies
  79. Biosceptre International
  80. BioTherapeutics Unit (BTU)
  81. bluebird bio
  82. Bone Therapeutics
  83. Boya Jiyin
  84. BoYuan RunSheng Pharma (Hangzhou)
  85. Bristol Myers Squibb
  86. Cabaret Biotech
  87. Calibr
  88. California Institute for Regenerative Medicine
  89. Cancer Research UK
  90. Cancer Prevention Research Institute of Texas
  91. Capricor Therapeutics
  92. Carina Biotech
  93. Carlos III Health Institute (Instituto de Salud Carlos III)
  94. CARsgen Therapeutics
  95. Cartesian Therapeutics
  96. Cartherics
  97. Case Comprehensive Cancer Center
  98. Case Western Reserve University
  99. Casebia Therapeutics
  100. Celdara Medical
  101. Celgene
  102. Cell and Gene Therapy Catapult
  103. Cell Design Labs
  104. Cell Manufacturing Technologies (CMaT)
  105. Cell Therapies Core
  106. Cell Therapy and Regenerative Medicine
  107. Cell Therapy Manufacturing Cooperative Research Centre (CTM CRC)
  108. Cell Therapy Suite
  109. Cellectis
  110. CELLforCURE
  111. Cellin Technologies
  112. Cells for Sight Stem Cell Therapy Research Unit
  113. Cellular Biomedicine Group (CBMG)
  114. Cellular Therapy Core (CTC)
  115. Cellular Therapy Integrated Services (CTIS)
  116. Celyad Oncology
  117. Center for Cell and Gene Therapy
  118. Center for Gene and Cell Processing (CGCP)
  119. Center for International Blood and Marrow Transplant Research
  120. Center of Excellence for Cellular Therapy (C3i)
  121. Central South University
  122. Centre for Biological Engineering
  123. Centre for Cell and Vector Production (CCVP)
  124. Centre for Cell Manufacturing Ireland (CCMI)
  125. Centre for Stem Cell Research (CSCR)
  126. Changhai Hospital
  127. Changshu Frist People's Hospital
  128. Changzheng Hospital
  129. Children’s Hospital of Philadelphia
  130. Children's GMP / GMP facility St. Jude Children's Research Hospital
  131. Children's Hospital and Health System Foundation
  132. Children's Hospital of Fudan University
  133. Children's Hospital of Philadelphia
  134. Children's Mercy Hospital Kansas City
  135. China (Nanjing) Cell Valley (CNCV)
  136. China Immunotech (Beijing) Biotechnology
  137. China Meitan General Hospital
  138. China Regenerative Medicine International (CRMI)
  139. Chinese Academy of Sciences
  140. Chinese PLA General Hospital
  141. Chongqing Precision Biotech
  142. City of Hope Medical Center
  143. City of Hope National Medical Center
  144. Cleans Cells
  145. Clinical Cell and Vaccine Production Facility (CVPF)
  146. Clinical Research Facility
  147. Cognate BioServices
  148. Columbia University
  149. Connell and O'Reilly Families Cell Manipulation Core Facility (CMCF)
  150. Cook Myosite
  151. Corondo Biosciences
  152. Creative Biolabs
  153. CRISPR Therapeutics
  154. Cryoport
  155. CSIRO
  156. CTI Clinical Trial and Consulting Services
  157. CureSearch for Children's Cancer
  158. CytoLumina Technologies
  159. CytoMed Therapeutics
  160. Cytopeutics
  161. Dana-Farber / Harvard Cancer Center
  162. Dana-Farber Cancer Institute
  163. Dartmouth College
  164. Delenex Therapeutics
  165. Dendreon
  166. DLR German Aerospace Center
  167. Dongguan People's Hospital
  168. Duke University
  169. Editas Medicine
  170. Eli Lilly
  171. Emory Personalized Immunotherapy Core
  172. Endocyte
  173. Eureka Therapeutics
  174. Eutilex
  175. EXUMA Biotechnology
  176. Fate Therapeutics
  177. Federal Research Institute of Pediatric Hematology
  178. FetoLumina Technologies
  179. First Affiliated Hospital of Chengdu Medical College
  180. First Affiliated Hospital of Chongqing Medical University
  181. First Affiliated Hospital of Harbin Medical University
  182. First Affiliated Hospital of Wenzhou Medical University
  183. First Affiliated Hospital of Zhejiang University
  184. First Hospital of Jilin University
  185. First People's Hospital of Foshan
  186. Five Prime Therapeutics
  187. Fondazione Matilde Tettamanti Menotti De Marchi Onlus
  188. Fondo Social La Caixa
  189. Fondos ARI (Assistencia Recerca Intensiva)
  190. Forevertek Biotechnology
  191. Formula Pharmaceuticals
  192. Fosun Kite Biotechnology
  193. Fosun Pharma
  194. Foundation for Biomedical Research and Innovation at Kobe
  195. Fraunhofer Institute for Cell Therapy and Immunology
  196. Fred Hutchinson Cancer Research Center
  197. Froceth
  198. Fujian Medical University
  199. Fujifilm
  200. Fundamenta Therapeutics
  201. Gamida Cell
  202. Gates Biomanufacturing Facility
  203. GC Pharma
  204. GE Research
  205. GE Healthcare Life Sciences
  206. GenCure
  207. Gene and Cell Therapy Lab
  208. Genentech
  209. General Hospital of People’s Liberation Army (PLAGH)
  210. GenIbet Biopharmaceuticals
  211. Genus Oncology
  212. Gilead Sciences
  213. GlaxoSmithKline
  214. Glycostem Therapeutics
  215. GlyTherix
  216. Gracell Biotechnologies
  217. Great Ormond Street Hospital for Children (GOSH)
  218. Guangdong General Hospital
  219. Guangdong Zhaotai InVivo Biomedicine
  220. Guangzhou Eighth People’s Hospital
  221. Guangzhou Anjie Biomedical Technology
  222. Guangzhou First People's Hospital
  223. Guy's and St Thomas' Facility
  224. H. Lee Moffitt Cancer Center and Research Institute
  225. Harvard University
  226. Hebei Senlang Biotechnology
  227. Hebei Yanda Lu Daopei Hospital
  228. Hefei Binhu Hospital
  229. Hefei First People’s Hospital
  230. Helix BioPharma
  231. Henan Cancer Hospital
  232. Henan Hualong Biotech
  233. Henan Provincial People's Hospital
  234. Histocell
  235. Hitachi Chemical Advanced Therapeutics Solutions
  236. Holostem Terapie Avanzate
  237. Horizon Discovery
  238. Hrain Biotechnology
  239. HuaDao (Shanghai) Biomedical
  240. Huaian First People's Hospital
  241. Huazhong University of Science and Technology
  242. Hunan Provincial People's Hospital
  243. Hunan Yongren Medical Innovation
  244. Hunan Zhaotai Yongren Biotech
  245. iCAR Bio Therapeutics
  246. iCarTAB BioMed
  247. iCell Gene Therapeutics
  248. Icell Kealex Therapeutics
  249. ICON
  250. Immetacyte
  251. Immune Therapeutics
  252. Immunovative Therapies
  253. Imperial College London
  254. Inhibrx
  255. Innovative Cellular Therapeutics
  256. Institut Curie
  257. Institute of Cancer Research
  258. Institute of Hematology & Blood Diseases Hospital
  259. Institute of Translational Health Sciences
  260. Intellia Therapeutics
  261. Interdisciplinary Stem Cell Institute
  262. International Stem Cell
  263. Intrexon
  264. Invectys
  265. Janssen
  266. Japanese Society for Regenerative Medicine
  267. Jiangsu Province Hospital of Traditional Chinese Medicine
  268. Jiangyin People's Hospital
  269. Jichi Medical University
  270. Jingjiang People's Hospital
  271. Jingzhou Central Hospital
  272. Jiujiang University Affiliated Hospital
  273. John Goldman Centre for Cellular Therapy
  274. Jonsson Comprehensive Cancer Center
  275. Juno Therapeutics
  276. Juventas Cell Therapy
  277. JW Therapeutics
  278. Kadimastem
  279. KAEDI
  280. Karolinska institute
  281. KBI Biopharma
  282. Kecellitics Biotech
  283. Kiadis Pharma
  284. King's College London
  285. Kite Pharma
  286. Kurr Therapeutics
  287. Laboratory for Cell and Gene Medicine
  288. Legend Biotech
  289. Leucid Bio
  290. Leukemia & Lymphoma Society
  291. Leukemia Research Foundation
  292. Lianyungang Hospital Affiliated Bengbu Medical College
  293. Life Technologies
  294. Liminatus Pharma
  295. Lineage Cell Therapeutics
  296. Lion TCR
  297. Living Pharma
  298. Longeveron
  299. Lonza
  300. Loughborough University
  301. Loyola University Medical Center
  302. LUMICKS
  303. MabQuest
  304. MabVax Therapeutics Holdings
  305. Malaghan Institute of Medical Research
  306. Marino Biotechnology
  307. Marker Therapeutics
  308. Massachusetts General Hospital
  309. MaSTherCell
  310. Max Delbrück Center for Molecular Medicine
  311. MaxCyte
  312. McMaster University
  313. McMaster University- Biomedical Engineering and Advanced Manufacturing (BEAM)
  314. MD Anderson Cancer Center
  315. Medical College of Wisconsin
  316. MedImmune
  317. MEDINET
  318. Medipost
  319. Medisix Therapeutics
  320. MedStar Georgetown University Hospital
  321. Memorial Sloan Kettering Cancer Center
  322. Merck
  323. Mesoblast
  324. Mie University
  325. Miller School of Medicine
  326. Miltenyi Biomedicine
  327. Minerva Biotechnologies
  328. MingJu Therapeutics
  329. Minovia Therapeutics
  330. Moffitt Cancer Center
  331. Molecular and Cellular Therapeutics
  332. MolMed
  333. Mustang Bio
  334. Nanfang Hospital of Southern Medical
  335. Nanjing Bioheng Biotech
  336. Nanjing Children's Hospital
  337. Nanjing KAEDI Biotech
  338. NantKwest
  339. National Cancer Center Japan
  340. National Cancer Institute
  341. National Heart, Lung, and Blood Institute
  342. National Institutes of Health
  343. National Marrow Donor Program
  344. National University of Ireland Galway
  345. NeoSTEM
  346. Netherlands Cancer Institute
  347. Neuralstem
  348. Newcastle Advanced Therapies
  349. New Jersey Innovation Institute (NJII)
  350. NHS Blood and Transplant
  351. Nikon CeLL innovation
  352. Ningbo Cancer Hospital
  353. NIPRO
  354. Nkarta
  355. Nohla Therapeutics
  356. Noile-Immune Biotech
  357. Notch Therapeutics
  358. Novadip
  359. Novartis
  360. Obsidian Therapeutics
  361. Oncodesign Biotechnology
  362. Oncora Medical
  363. ONCOTracker
  364. OnCyte
  365. oNKo-innate
  366. ONO Pharmaceutical
  367. Opus Bio
  368. Orgenesis
  369. Ospedale Pediatrico Bambino Gesù (OPBG)
  370. Otsuka Pharmaceutical
  371. Ottawa Hospital Research Institute
  372. Oxford BioMedica
  373. Oxford MEStar and AK (Suzhou) Biomedical
  374. panCELLa
  375. Parker Institute for Cancer Immunotherapy
  376. Peking Union Medical College Hospital
  377. Peking University
  378. Peking University People's Hospital
  379. PeproMene Bio
  380. PersonGen BioTherapeutics
  381. Peter MacCallum Cancer Centre
  382. Pfenex
  383. PharmaBio
  384. Pharmicell
  385. Phio Pharmaceuticals
  386. Pinze Lifetechnology
  387. Pluristem Therapeutics
  388. Poseida Therapeutics
  389. Praxis Pharmaceutical
  390. Precision Biosciences
  391. Pregenen
  392. Princess Margaret Hospital
  393. ProMab Biotechnologies
  394. Promethera Biosciences
  395. Protheragen
  396. Provia Laboratories
  397. Purdue University
  398. PureTech Health
  399. Q-Gen Cell Therapeutics
  400. QIMR Berghofer Medical Research Institute
  401. Rayne Cell Therapy Suite (King's College London)
  402. Regeneron Pharmaceuticals
  403. ReNeuron
  404. RenJi Hospital
  405. Research and Development Center for Cell Therapy (RDC)
  406. resTORbio
  407. Rexgenero
  408. Riyadh Pharmaceutical
  409. Rockland Immunochemicals
  410. Roger Williams Medical Center
  411. Roslin Cells
  412. Roswell Park Cancer Institute
  413. Royal Adelaide Hospital Cancer Centre
  414. Rubius Therapeutics
  415. Ruijin Hospital
  416. Russian Direct Investment Fund
  417. S.Biomedics
  418. Samsung BioLogics
  419. San Diego Regenerative Medicine Institute
  420. Sangamo Therapeutics
  421. Scientific and Technological Research Council of Turkey
  422. SCM Lifescience
  423. Scotia Biologics
  424. Scottish National Blood Transfusion Service (SNBTS)
  425. Scripps Research
  426. Seattle Cancer Care Alliance
  427. Seattle Children's Hospital
  428. Seattle Children's Research Institute
  429. Second Affiliated Hospital of Guangzhou Medical University
  430. Second Affiliated Hospital of Nanchang University
  431. Second Affiliated Hospital of Xi'an Jiaotong University
  432. Second Military Medical University
  433. Second Xiangya Hospital of Central South University
  434. Sensei Biotherapeutics
  435. Servier
  436. Shangai Cancer Institute (SCI)
  437. Shanghai Tenth People’s Hospital
  438. Shanghai Sixth People's Hospital
  439. Shanghai Biomed-union Biotechnology
  440. Shanghai Bioray Laboratory
  441. Shanghai Cell Therapy Group
  442. Shanghai Cell Therapy Research Institute
  443. Shanghai Changzheng Hospital
  444. Shanghai Chest Hospital
  445. Shanghai Children's Medical Center
  446. Shanghai East Hospital
  447. Shanghai GeneChem
  448. Shanghai International Medical Center
  449. Shanghai Jiao Tong University School of Medicine
  450. Shanghai Longyao Biotechnology
  451. Shanghai PerHum Therapeutics
  452. Shanghai Public Health Clinical Center (SPHCC)
  453. Shanghai Tongren Hospital
  454. Shanghai Tongji Hospital
  455. Shanghai UniCAR-Therapy Bio-Medicine Technology
  456. Shanghai Zhongshan Hospital
  457. Sheba Medical Center
  458. Shenzhen Binder Biotechnology
  459. Shenzhen Children's Hospital
  460. Shenzhen Geno-immune Medical Institute
  461. Shenzhen Hospital of Southern Medical University
  462. Shenzhen Institute for Innovation and Translational Medicine
  463. Shenzhen Second People's Hospital
  464. Shenzhen University (SZU)
  465. ShiJiaZhuang Zhongxi Children Hospital
  466. Sichuan University
  467. Sidney Kimmel Cancer Center
  468. Simcere Pharmaceutical
  469. Sinobioway Cell Therapy
  470. Sorrento Therapeutics
  471. SOTIO
  472. South London and Maudsley NHS Foundation Trust
  473. Southern Medical University
  474. SpringWorks Therapeutics
  475. St. Baldrick's Foundation
  476. St. Jude Children's Research Hospital
  477. St. Michael’s Hospital
  478. Stage Cell Therapeutics
  479. Stanford University
  480. Stem Cell Institute
  481. Stemedica Cell Technologies
  482. Stemmatters
  483. Stempeutics Research
  484. Stony Brook University
  485. Stratophase
  486. Sumitomo Dainippon Pharma
  487. Sun Yat-Sen University
  488. Suzhou Municipal Hospital
  489. Sydney Cell and Gene Therapy
  490. Synthace
  491. SZU General Hospital
  492. Takara Bio
  493. Takeda Pharmaceutical
  494. Tang Du Hospital
  495. Targazyme
  496. TC BioPharm
  497. Tel Aviv Sourasky Medical Centre (Ichilov)
  498. TeneoBio
  499. Terumo BCT
  500. Tessa Therapeutics
  501. Texas Children's Hospital
  502. The Affiliated Hospital of Guizhou Medical University
  503. The Affiliated Drum Tower Hospital of Nanjing University Medical School
  504. The Beijing Pregene Science and Technology
  505. The First Affiliated Hospital of Anhui Medical University
  506. The First Affiliated Hospital of Guangdong Pharmaceutical University
  507. The First Affiliated Hospital of Kunming Medical University
  508. The First Affiliated Hospital of Nanchang University
  509. The First Affiliated Hospital of Soochow University
  510. The First Affiliated Hospital of Zhengzhou University
  511. The First Affiliated Hospital with Nanjing Medical University
  512. The First People's Hospital of Yuhang District
  513. The First People's Hospital of Yunnan
  514. The Health Sciences Authority
  515. The Islet and Cellular Transplant Facility
  516. The Krembil Good Manufacturing Practice Cell Facility
  517. The Ohio State University
  518. The Philip S. Orsino Cell Therapy Facility
  519. The Pregene ShenZhen Biotechnology
  520. The Second Affiliated Hospital of Chongqing Medical University
  521. The Second Affiliated Hospital of Hainan Medical University
  522. The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine
  523. The Second Hospital of Anhui Medical University
  524. The Second Hospital of Hebei Medical University
  525. The Second Hospital of Nanjing Medical University
  526. The Second Military Medical University (SMMU)
  527. The Second People's Hospital of Huai'an
  528. The Seventh Affilliated Hospital
  529. The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  530. The Sixth Affiliated Hospital of Wenzhou Medical University
  531. The Third Affiliated Hospital of Southern Medical University
  532. The Wistar Institute
  533. Therapeutic Cell Production Core (TCPC)
  534. ThermoFisher
  535. Third Military Medical University
  536. Tianjin Medical University Cancer Institute and Hospital
  537. Tianjin Pharmacn Medical Technology
  538. Tianjin People's Hospital
  539. TILT Biotherapeutics
  540. Timmune Biotech
  541. Tmunity Therapeutics
  542. Tongji University
  543. Toni Stephenson Lymphoma Center
  544. ToolGen
  545. Torque Pharmaceuticals
  546. TrakCel
  547. Transgene
  548. Transposagen Biopharmaceuticals
  549. TreeFrog Therapeutics
  550. TriArm Therapeutics
  551. Trinity College
  552. Tri-Service General Hospital
  553. TVAX Biomedical
  554. UC Davis Good Manufacturing Practice Laboratory
  555. UCLA Human Gene and Cell Therapy Facility (HGCTF)
  556. UNC Lineberger Comprehensive Cancer Center
  557. Union Stem Cell & Gene Engineering
  558. United States Department of Defense
  559. University College London
  560. University Health Network (UHN)
  561. University Hospital Basel
  562. University Hospital Heidelberg
  563. University Hospital Würzburg
  564. University of Birmingham
  565. University of California
  566. University of Cologne
  567. University of Colorado
  568. University of Florida
  569. University of Manchester
  570. University of Miami
  571. University of Milano-Bicocca
  572. University of Minnesota
  573. University of North Carolina Lineberger Comprehensive Cancer Center
  574. University of Oxford
  575. University of Pennsylvania
  576. University of Rochester
  577. University of Technology Sydney
  578. University of Texas
  579. University of Toronto
  580. University of Utah
  581. University of Washington
  582. University of Zurich
  583. Uppsala University
  584. Upstate Stem Cell cGMP Facility
  585. UWELL Biopharma
  586. V Foundation
  587. Vaccinogen
  588. Vecura (Karolinska University Hospital)
  589. Vericel
  590. VetStem Biopharma
  591. ViroMed Laboratories
  592. Vitruvian Networks
  593. Waisman Biomanufacturing
  594. Washington University
  595. Weill Cornell Medical College of Cornell University
  596. Wellington Zhaotai Therapies
  597. West China Hospital
  598. WindMIL Therapeutics
  599. Wuhan Bio-Raid Biotechnology
  600. Wuhan Sian Medical Technology
  601. Wuhan Union Hospital
  602. WuXi AppTec
  603. Xiangyang Central Hospital
  604. Xijing Hospital
  605. Xinqiao Hospital
  606. Xuanwu Hospital of Capital Medical University
  607. Xuzhou Medical University
  608. Yake Biotechnology
  609. Yale School of Medicine
  610. Yamaguchi University
  611. Yan'an Affiliated Hospital of Kunming Medical University
  612. Yuan Yi Biotechnology
  613. Yunnan Cancer Hospital
  614. Zelluna Immunotherapy
  615. Zhangjiagang First People's Hospital
  616. Zhejiang University (ZJU)
  617. Zhujiang Hospital
  618. Ziopharm Oncology

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