Top 5 Modular Cleanroom Manufacturers
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Published: March 2024
The future success of the modular construction market is driven by strategic initiaives by modular cleanroom manufactuters. We analyzed over 50 companies that are engaged in the development of modular cleanrooms. In this article, discover top 5 modular building companies and their service portfolio related to modular cleanrooms.
Modular facilities are prefabricated buildings that are built using multiple sections, often known as modules. Primarily, the key difference between these and conventional buildings is the fact that modular constructs or modular cleanrooms are designed, engineered and manufactured off-site, and later delivered to the intended site of use for final installation. It is worth noting that, in order to ensure that all critical systems are precisely configured, compliant to existing guidelines and fully operational, the modules are tested before shipping. In recent years, the focus of the pharmaceutical industry has shifted from mass production of blockbuster drugs for large patient populations to small batch production of personalized drugs targeting specific subpopulations of patients. The rising demand for personalized therapies has led to the increase in opportunities for modular cleanroom manufacturers. Driven by the availability of innovative technologies, lucrative funding opportunities and substantial partnerships, the modular cleanroom manufacturers market is poised to grow in the long-run.
Roots Analysis has conducted an exhaustive study on Modular Construction Market featuring the current market landscape and future opportunity for the companies offering modular construction services, over a span of 12 years.
Table of Contents
Below, we have listed (in alphabetical order), the top 5 modular building companies.
- Cytiva
- G-CON Manufacturing
- Germfree
- NNE
- Pharmadule
Interested in exploring all 50+ modular cleanroom manufacturers and their recent initiatives?
Discover Below the Details on Top 5 Modular Cleanroom Manufacturers
Let us deep dive to understand the activity of the top 5 modular cleanroom manufacturers (shortlisted on the basis of service portfolio). It is essential to note that the selection of top players can differ substantially according to the defined criteria.
Cytiva, Pioneering Single-Use Technology in Bioprocess Manufacturing with FlexFactory and KUBio Modular Solutions
1. Cytiva
Cytiva (formerly GE Healthcare) is a US-based biotechnology company that provides KUBio platform, a cGMP-compliant modular solution, including both the facility and the required equipment for bioprocess manufacturing. Further, the bioprocess platform used within the facility is FlexFactory. The aforementioned platform is primarily built with single-use technology. It consists of multiple unit operations connected by single-use tubing sets and can be automated in a number of ways. It is worth mentioning that the firm’s operations span across 40 countries. Moreover, it has established 11 customer centered innovation facilities, globally.
Cytiva: Company Details
| Particulars | Specifications |
| Company Logo |  |
| Year of Establisment | 1892 |
| Number of Employees | 10,000 |
| Headquarter |  |
| Key Executives |
|
Cytiva: Modular Construction Services
| Particulars | Specifications |
| FlexFactory |
|
| KUBio Box |
|
Cytiva: Modular Construction Projects
| S.No. | Client | Type of Modular Facility | Location | Purpose of Facility | Project Completion Year |
| 1 | Taiyo Pharma Tech | Manufacturing Facility | Osaka, Japan | Gene Therapy Medicines | 2023 |
| 2 | Lonza | Manufacturing Facility | Guangzhou, China | Antibody Development | 2021 |
| 3 | BeiGene | Manufacturing Facility | Guangzhou, China | Monoclonal Antibodies | 2019 |
| 4 | Pfizer | Manufacturing Facility | Hangzhou, China | Biosimilars | 2018 |
Recent Development: In December 2021, Cytiva entered into a supply agreement with Taiyo Pharma Tech to deliver FlexFactory solution for the development of gene therapy medicines based on AAV vector (adeno-associated viruses). Earlier, in January 2021, the company had entered into a supply agreement with Lonza to deliver a 17,000 sq. m modular biomanufacturing facility for the development and manufacturing of biologic.
Further details on recent initiatives taken by Cytiva as well as other modular cleanroom manufacturers have been provided in detail in the report.
G-Con Manufacturing: Leading the Way in Prefabricated Cleanrooms for Flexible and Scalable Pharma Manufacturing
2. G-Con Manufacturing
G-Con Manufacturing is a privately held, US based company that claims to be engaged in the construction and installation of prefabricated containment cleanrooms, called PODs. As per the firm’s website, its autonomous cleanroom PODs can be deployed to provide sufficient flexibility, mobility and scalability in order to cater to the manufacturing requirements for cell therapies, viral vectors and personalized medicines.
G-Con Manufacturing: Company Details
| Particulars | Specifications |
| Company Logo |  |
| Year of Establisment | 2009 |
| Number of Employees | 51-200 |
| Headquarter |  |
| Key Executives |
|
G-Con Manufacturing: Modular Construction Services
| Modular Services | Type | Description |
| Products |
Standard POD
megaPOD
POD Cluster
|
|
| Integrated Solutions |
Microcell POD
Pall Viral Vector POD
iCON |
|
G-Con Manufacturing: Modular Construction Projects
| S.No. | Client | Type of Modular Facility |
Location | Type of Product | PCY |
| 1 | CytoImmune Therapeutics |
Manufacturing Cleanroom Facility | California, US | Cell Therapy | 2022 |
| 2 | TrueBinding | Manufacturing Cleanroom Facility | California, US | Biotherapeutics | 2022 |
| 3 | Codiak BioSciences | Manufacturing Cleanroom Facility | Massachusetts, US | Exosome | 2020 |
| 4 | Rubius Therapeutics | Manufacturing Cleanroom Facility | Rhode Island, US | Cell Therapy | 2020 |
| 5 | GenCure | Manufacturing Cleanroom Facility | Texas, US | Cell Therapy | 2019 |
Recent Development: In May 2022, G-Con Manufacturing entered into a supply agreement with CytoImmune Therapeutics to deliver a cleanroom infrastructure for the development and manufacturing of NK cells. Earlier, in April 2022, the company announced the acquisition of Plasteurop to expand its product portfolio / capabilities related to the production of cleanroom components.
Further details on recent initiatives taken by G-Con Manufacturing as well as other modular cleanroom manufacturers have been provided in detail in the report.
Germfree: Innovating Modular Cleanrooms for cGMP Compliance and Pharmaceutical Excellence
3. Germfree
Germfree is a US-based company that claims to deliver solutions for laboratory equipment, cleanrooms, biosafety labs and cGMP facilities to pharmaceutical and biotechnology industries. As per the company’s website, its bioGO modular cleanrooms are designed to meet the cGMP guidelines established for drug development and production. Additionally, these facilities are available in multiple configurations to meet the client’s requirements. The company provides single-source original equipment manufacturer (OEM) solutions enabling faster delivery of modular facilities that are ready for operation. It is worth mentioning that the firm claims to have deployed more than 200 facilities, across the globe.
Germfree: Company Details
| Particulars | Specifications |
| Company Logo |  |
| Year of Establisment | 1962 |
| Number of Employees | 51-200 |
| Headquarter |  |
| Key Executives |
|
Germfree: Modular Construction Services
| Modular Service | Products |
| Biopharma Modules |
|
| Biocontainment Modular Laboratories |
|
| Modular Compounding Pharmacies |
|
Recent Development: In October 2023, Germfree announced the launch of decentralized mobile manufacturing platform, seamlessly integrated with an advanced manufacturing operating system, in collaboration with Title21, for cell and gene therapy manufacturing.
Further details on recent initiatives taken by Germfree as well as other modular cleanroom manufacturers have been provided in detail in the report.
NNE: Empowering Pharma Innovation with Expertise in Future-Proof Engineering Solutions
4. NNE
NNE is a privately held biotechnology company that has expertise in pharma engineering and delivers flexible and future-proof solutions to the pharmaceutical players, in order to bring products to the market. Additionally, it is engaged in providing facility design services for cleanrooms, cGMP facilities and biocontainment plants. It is worth highlighting that, earlier, the firm was owned by Novo Nordisk and was known as NNE Pharmaplan. However, in 1991, it became an independent company. Subsequently, in February 2017, it changed its name to NNE.
NNE: Company Details
| Particulars | Specifications |
| Company Logo |  |
| Year of Establisment | 1991 |
| Number of Employees | 1,001-5000 |
| Headquarter |  |
| Key Executives |
|
NNE: Modular Construction Services
NNE: Modular Construction Projects
| S.No. | Client | Type of Modular Facility | Location of Facility | Service Provided | Project Completion Year |
| 1 | Shanghai Junshi Biosciences | Manufacturing Facility | Shanghai, China | Conceptual and Basic Design | 2019 |
| 2 | Emergent Biosolution | Manufacturing Facility | Baltimore, US | Conceptual Design | 2017 |
Recent Development: In May 2023, NNE announced the opening of new office in Bangalore, India. Earlier in December 2021, NNE entered into a supply agreement with Novo Nordisk to expand their existing infrastructure in Kalundborg to produce current and future oral and injectable products.
Further details on recent initiatives taken by NNE as well as other modular cleanroom manufacturers have been provided in detail in the report.
Pharmadule, Revolutionizing Pharma Production with Global Modular Solutions and Industry-Leading Expertise
5. Pharmadule
In June 2011, Morimatsu Industry Group acquired Pharmadule, an engineering company that designs, constructs and delivers modular production facilities for pharmaceutical, biopharmaceutical and life science industries, across the globe. Following the acquisition, the company currently operates as Pharmadule Morimatsu. It claims to have delivered more than 70 production facilities based on the modular concept, to its clients across the globe. It is also worth mentioning that the modular concept has so far been used by leading pharmaceutical companies, such as AstraZeneca, Baxter International, Eli Lilly, Genentech, GlaxoSmithKline, Merck and Pharmacia.
Pharmadule: Company Details
| Particulars | Specifications |
| Company Logo |  |
| Year of Establisment | 2011 |
| Number of Employees | 51-200 |
| Headquarter |  |
| Key Executives |
|
Pharmadule: Modular Construction Services
Pharmadule: Modular Construction Projects
| S.No. | Name of Client | Type of Modular Facility |
Location | Type of Project | PCY |
| 1 | Undisclosed African Partner | Manufacturing Facility | Africa | Pharmaceutical | 2022 |
| 2 | WALVAX | Manufacturing Facility | Asia-Pacific | Pharmaceutical | 2021 |
| 3 | Lonza | Manufacturing Facility | Asia-Pacific | Biopharmaceutical | 2019 |
| 4 | Undisclosed Global Pharmaceutical Company |
Fill and Finish Facility | MEA Region | Pharmaceutical | 2018 |
Recent Development: In May 2023, Pharmadule announced the completion of delivery of its EIPICO3 (first monoclonal antibody and small molecule protein hybrid production plant and filling plant in Egypt) modular pharmaceutical plant project based in Cairo for Egyptian International Pharmaceutical Industries Company.
Further details on recent initiatives taken by Pharmadule as well as other modular cleanroom manufacturers have been provided in detail in the report.
What About the Other Modular Cleanroom Manufacturers Around the World?
The above presentation features top five modular cleanroom manufacturers selected from a pool of more than 50 modular construction companies that we have compiled. If you're interested, you can download the Sample Report on this topic by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com.