Top 10 Viral Vector Manufacturing Companies

Published: March 2026

Viral vectors are the biological tools that are used to transport genetic material to the target cell. Despite being a complex and resource-intensive process, development and manufacturing of cell and gene therapies has gained substantial momentum, with an increasing number of clinical programs moving to later-phase clinical trials and towards market approval. There are currently over 30 commercially available cell and gene therapy products, along with hundreds of ongoing clinical trials for these innovative therapies. Further, this domain has witnessed a significant increase in the number of clinical candidates due to the COVID-19 pandemic.

Apart from various applications in gene therapy, cell therapy and vaccine, certain virus, such as vaccinia virus, CMV, Sendai virus and adenovirus, are being used to immunize patients against HIV-1, influenza, hepatitis, tuberculosis, and malaria. It is expected that the biotechnology sector is likely to explore novel technologies to decrease the overall vector manufacturing cost. To date, there are numerous advancements adopted in vector manufacturing domain, including adoption of modular facilities and disposable / single use bioreactors, and the development of automated cell processing systems for cell and gene therapy processes. In addition, the viral vector manufacturers along with cell and gene therapy developers are actively investing in the infrastructure that will be required to support the current pipeline.

Further, in order to meet the increasing demand for vectors, contract manufacturers, such as Lonza, Fujifilm Diosynth and Thermo Fisher Scientific have identified the gaps in the market and are aggressively expanding their production capacity. Moreover, various newly forged alliances between academic and industry players are expected to be complementary and instrumental in addressing the challenges in this domain.

Roots Analysis has conducted an exhaustive study on Viral Vector Manufacturing Market featuring the current market landscape and future opportunity for viral vector manufacturing companies offering contract services, till 2035.

Top Ten Leading Viral Vector Manufacturers

Advanced BioScience Laboratories
AGC Biologics
Aldeveron
Catalent Biologics
Charles River Laboratories
Lonza
Novartis
Oxford Biomedica
Thermo Fisher Scientific
VectorBuilder

The figure below highlights the top ten viral vector manufacturers:

Top 10 Viral Vector Manufacturing Companies

Interested in exploring all 135+ viral vector manufacturing companies and their recent initiatives?

Discover Below the Details on Top 10 Viral Vector Manufacturing Companies

Let us deep dive to understand the activity of the top 10 viral vector manufacturing companies. It is essential to note that the selection of top players can differ substantially according to the defined criteria.

1. Advanced BioScience Laboratories

Advanced BioScience Laboratories is a US-based contract research and manufacturing organization, which offers viral and non-viral vector manufacturing services for vaccines and other therapies at the preclinical, clinical, and commercial scales of operation. It is interesting to highlight that these services include manufacturing of several types of viral vectors, including adeno associated viruses, adeno viruses, arena viruses, measles viruses and pox viruses.

Further, the firm also offers development and manufacturing services for virus and protein production, using single-use bioreactor platforms and other technologies, through its facilities located in the US and Europe. Interestingly, the company’s offerings include additional services to support manufacturing of aforementioned products including cell line and process development, GMP manufacturing, QC release testing and QA / regulatory support.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Advanced BioScience Laboratories, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors and Lentiviral Vectors
Location of Manufacturing Facility: North Dakota, US; Nebraska, US; Wisconsin, US
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Gene Therapy and Cell Therapy

Recent Development: In November 2025, Advanced BioScience Laboratories entered into a collaboration with Ginkgo Bioworks under a project agreement from BARDA's BioMaP Consortium. ABL will provide its GMP viral vector and biologics manufacturing expertise to optimize and streamline production processes for Ginkgo Bioworks.

To know more about the recent initiatives of Advanced BioScience Laboratories and other vector manufacturers, access full report.

2. AGC Biologics

AGC Biologics is a global CDMO, focused on development as well as offering manufacturing services, for protein-based antibodies, enzymes, plasmid DNA, mRNA, viral vectors and other pharmaceutical ingredients using mammalian and microbial production systems. In addition, the company offers services for analytical testing, antibody drug development and conjugation, bioprocess development, cell banking and storage, cell line development, formulation, and protein expression. The company claims to comply with GMP guidelines for its development and manufacturing operations

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by AGC Biologics, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Lentiviral Vectors and Retroviral Vectors
Location of Manufacturing Facility: Colorado, US; Milan, Italy; Bresso, Italy
Scale of Operation: Clinical and Commercial
Application Areas: Gene Therapy and Cell Therapy

Recent Development: In November 2025, AGC Biologics signed a manufacturing agreement with AAVantgarde to produce dual-AAV gene therapies for inherited retinal disorders utilizing its BravoAAV high-yield suspension platform.

To know more about the recent initiatives of AGC Biologics and other vector manufacturers, access full report.

3. Aldeveron

Aldevron is a US-based firm claims to offer various services for the manufacturing of enzymes, plasmid DNA, proteins, and biologics, for the purpose of research, and other clinical and commercial applications. With an experience of more than 20 years, the firm offers a wide range of services related to plasmid DNA manufacturing, including plasmid design, production, purification, and analytical testing.

Additionally, Aldevron has developed proprietary manufacturing technologies that enable the production of high-quality plasmid DNA in a scalable and cost-effective manner.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Aldevron, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors and Lentiviral Vectors
Location of Manufacturing Facility: North Dakota, US; Nebraska, US; Wisconsin, US
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Gene Therapy and Cell Therapy

Recent Development: In October 2025, Aldevron enrolled in the G-Rex Grant Program. This partnership will provide over 300 grant recipients with exclusive offers on research-use and GMP-grade plasmids, vectors, and proteins (including nucleases/enzymes) to support scalable cell and gene therapy manufacturing.

To know more about the recent initiatives of Aldeveron and other vector manufacturers, access full report.

4. Catalent Biologics

Catalent Biologics is a US-based contract development and manufacturing organization that is focused on product optimization, product launch, and product lifecycle for pharmaceutical, biotechnology, and consumer health partners. With a vast network of over 45 facilities worldwide, Catalent offers a comprehensive range of services, including formulation development, preclinical, clinical and commercial manufacturing, packaging, and advanced delivery technologies.

Further, It is worth highlighting that the company’s expertise extends to various dosage forms, such as oral, injectable, inhalable, and topical medications. In addition, through its Biologics unit, the firm offers development and manufacturing services for high-quality biopharmaceutical products, including cell and gene therapies.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Catalent Biologics, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Lentiviral Vectors, Retroviral Vectors, Plasmid DNA (Linearized) and Other Viral Vectors
Location of Manufacturing Facility: Charleroi, Belgium, Gosselies, Belgium and Maryland, US
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy , Gene Therapy and Vaccines

Recent Development: In January 2025, Catalent entered into a partnership with GenSight wherein Catalent will manufacture LUMEVOQ for GenSight's upcoming global Phase III RECOVER trial and regulatory submissions, improving yields and analytical methods for enhanced safety and quality.

To know more about the recent initiatives of Catalent Biologics and other vector manufacturers, access full report.

5. Charles River Laboratories

Charles River Laboratories is a US-based CDMO, offering basic research, drug discovery and development services, conducting safety and efficacy studies, and providing clinical support and manufacturing services across a wide range of therapeutic areas to pharmaceutical companies, biotechnology companies, government agencies, hospitals and academic institutions, worldwide. With over 75 years of experience, the firm offers viral vector and plasmid DNA manufacturing services as part of its cell and gene therapy CDMO solutions.

Further, it is worth mentioning that the company utilizes advanced technologies to produce high-quality viral vectors and plasmid DNA at various scales, catering to preclinical, clinical, and commercial requirements. Further, the company provides customizable plasmid and viral vector products to facilitate gene therapy discovery and research programs.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Charles River Laboratories, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Lentiviral Vectors, Retroviral Vectors and Plasmid DNA
Location of Manufacturing Facility: Keele, UK, Maryland, US , Matfors, Sweden and Sodertalje, Sweden
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy , Gene Therapy and Vaccines

Recent Development: In January 2026, Charles River Laboratories enters into a collaboration with Gazi University Faculty of Medicine with an aim to provide plasmid DNA for AAV production and in vitro efficacy studies.

To know more about the recent initiatives of Charles River Laboratories and other vector manufacturers, access full report.

6. Lonza

Lonza is a Switzerland based firm that offers contract manufacturing services in pharma and biotech domains. The company operates through more than 30 sites and offices, spread across the globe. Additionally, it offers R&D and manufacturing services to pharmaceutical clients worldwide. It is worth highlighting that the company entered into the viral vector manufacturing domain post acquiring Vivante GMP Solutions, in August 2010. Further, in April 2018, Lonza completed the construction of another state-of-the-art manufacturing facility in Houston for the development of viral gene therapies and virally modified cell therapies. In addition to viral vectors, the company is able to efficiently and effectively manufacture other biopharmaceuticals, including conjugated vaccines, new molecular formats, novel scaffolds, recombinant proteins, and plasmid DNA.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Lonza, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Lentiviral Vectors, Plasmid DNA and Other Viral Vectors
Location of Manufacturing Facility: Holland, Netherlands, New Hampshire, US, Texas, US and Tuas, Singapore
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy, Gene Therapy and Vaccines

Recent Development: In October 2025, Lonza expanded its cell and gene therapy portfolio by launching new GMP-grade cytokines and an AAV (adeno-associated virus) medium to improve scalability, consistency, and efficiency in viral vector and cell therapy production.

To know more about the recent initiatives of Lonza and other vector manufacturers, access full report.

7. Novartis

Novartis, a global healthcare company that leverages its innovative science and technology solutions to tackle complex healthcare challenges. The company’s focus lies in the discovery and development of breakthrough treatments while ensuring broad accessibility. The various business units through which the company operate include development, biomedical research, and operations. Additionally, it is worth noting that the company offers viral vector manufacturing services for cell and gene therapy, as well as vaccines, in a state-of-the-art facility. With an experienced team, robust upscaling capabilities, and stringent quality standards upheld by the company’s quality management system, it claims to be a trusted partner in viral vector production.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Novartis, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Lentiviral Vectors, Retroviral Vectors and Plasmid DNA
Location of Manufacturing Facility: Austria, Les Ulis, France, Switzerland
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy, Gene Therapy and Vaccines

Recent Development: In February 2025, Novartis opened its first European viral vector production facility, VIFA One, in Menges, Slovenia, following a EUR 40 million investment.

To know more about the recent initiatives of Novartis and other vector manufacturers, access full report.

8. Oxford Biomedica

Oxford BioMedica is a biopharmaceutical company headquartered in Oxford, UK. It was founded by professors of the Department of Biochemistry at the University of Oxford, Alan and Sue Kingsman, in 1995. The company claims to be the first in the world to get commercial approval for lentiviral based gene delivery system, their LentiVector platform can be utilized to administer innovative and life-changing ex vivo and in vivo treatments in patients.

The company has proprietary portfolio of cell and gene therapy candidates for the treatment of CNS disorders, liver disorders, oncology, ophthalmology and respiratory disorders. Further, the company offers a range of services including cGMP compliance, analytical development, facilities management, process transfer and improvement, quality assurance, quality control, regulatory support, supply chain management and technical operations.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Oxford Biomedica, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors and Lentiviral Vectors
Location of Manufacturing Facility: Oxford, UK
Scale of Operation: Clinical and Commercial
Application Areas: Gene Therapy, Cell Therapy and Vaccines

Recent Development: In February 2026, the company entered into multi-year commercial supply agreement with Bristol Myers Squibb for lentiviral vectors in CAR-T program.

To know more about the recent initiatives of Oxford Biomedica and other vector manufacturers, access full report.

9. Thermo Fisher Scientific

Thermo Fisher Scientific is a US-based global service provider specializing in life sciences research with the focus on solving complex analytical challenges and developing innovative technologies for its clients. The company operates globally through its industry-leading brands, including Applied Biosystems, Fisher Scientific, Invitrogen, Patheon, PPD and Unity Lab Services. The firm develops products for various fields, such as life sciences, clinical, diagnostic, industrial and applied sciences. In fact, the company states that it has manufactured more than 700 viral vector products, such as adeno-associated viral, adenoviral, retroviral, lentiviral and HSV vector by using variety of manufacturing technologies.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by Thermo Fisher Scientific, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Lentiviral Vectors, Retroviral Vectors, Plasmid DNA (Bacmid, Linearized, Nanoplasmid) and Other Viral Vectors
Location of Manufacturing Facility: California, US , Florida, US, Gosselies, Belgium, Massachusetts, US, Seneffe, Belgium
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy, Gene Therapy and Vaccines

Recent Development: In September 2025, Thermo Fisher Scientific partnered with Dr. Park CDMO, a South Korean viral vector contract development and manufacturing organization, to equip its new Phase I viral vector manufacturing facility.

To know more about the recent initiatives of Thermo Fisher Scientific and other vector manufacturers, access full report.

10. VectorBuilder

VectorBuilder is a US-based genetic engineering company. The firm offers a wide range of products and services catering to the diverse requirements of researchers and scientists worldwide. The firm’s comprehensive offerings include custom vector construction, virus packaging, gene synthesis, and genome editing services. In addition, it is worth mentioning that the company offers a free web-based platform that integrates advanced vector design capabilities with online ordering.

List of Type of Vectors Manufactured, Location of Manufacturing Facilities, Scale of Operation and Application Area

The section provides information on the vectors being manufactured by VectorBuilder, along with details on the type of vectors manufactured, location of manufacturing facilities, scale of operation and application area.

Type of Vector Manufactured: Adeno-associated Viral Vectors, Adenoviral Vectors, Retroviral Vectors, and Other Viral Vectors
Location of Manufacturing Facility: Illinois, US; Neu-Isenburg, Germany; Kanagawa, Japan; Guangzhou, China; Edinburgh, UK
Scale of Operation: Preclinical, Clinical and Commercial
Application Areas: Cell Therapy, Gene Therapy and Vaccines

Recent Development: In January 2026, VectorBuilder entered into a collaboration with Ikarovec in order to integrate its novel AAV capsid technology with Ikarovec's IKAR-003 gene therapy candidate.

To know more about the recent initiatives of VectorBuilder and other vector manufacturers, access full report.

What About other Viral Vector Manufacturers around the World?

The above article features the top ten viral vector manufacturers selected from a pool of other manufacturers that we have compiled. If you're interested, you can download the Sample Report on this topic by Roots Analysis. For personalized assistance in identifying the most relevant solutions based on your specific criteria, please don't hesitate to reach out to us at sales@rootsanalysis.com.

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