Category: Microbial Manufacturing

Next Generation Biomanufacturing – The Upcoming Era of Digital Transformation

Upon realizing the potential of digital biomanufacturing over traditional processes, players are actively undertaking initiatives to adopt advanced platforms to drive operational excellence, visibility, control and synchronization in bioprocessing. Industry 4.0: An amalgamation of physical equipment and smart software Digital biomanufacturing offers real-time process optimization based on factors, such as anticipated product quality and batch

Continuous Manufacturing System Providers

Over the years, several industries have implemented evolutionary changes in their respective manufacturing processes. One to the most rewarding advancements in this direction, is process automation. In pharmaceutical contract manufacturing, the automation of various aspects of the production process has led to the establishment of the continuous manufacturing system providers. However, the transition to continuous

Modular Cleanroom: A Paradigm Shift in Pharmaceutical Facilities

The concept of modular cleanroom has long been employed in other sectors, but it has only recently acquired traction in the pharmaceutical business over the last two to three decades. Modular cleanroom construction is a process wherein factory-produced, pre-engineered building units, which are constructed offsite under controlled plant conditions, are assembled on site to construct

Biologics CMO: Industry Outlook and the Growing Pipeline

The recent years have portrayed the renaissance in the domain of biologics, as pharmaceutical industry has once again gained attention towards the production of bioproducts. In fact, in 2019, a total of 28 biopharmaceutical products (including monoclonal antibodies, recombinant proteins and gene therapy) were approved in the US. Further, over 8,000 biological pharmaceutical products are

Microbial Fermentation: Growing Microbial-Based Biologics Pipeline

The recent years have portrayed the renaissance in the domain of microbial fermentation, as microbial biopharma industry has once again gained attention towards the production of biologics using microbial expression system. The modification and innovation in the microbial fermentation based expression systems for the production of various biologics have side-lined some of the earlier concerns

Microbial Fermentation Companies: Impact of the Pandemic

Since the discovery of recombinant DNA technology, several types of microbes have been established as a versatile biomolecule expression system. This can be attributed to the ease of handling of microbial cell lines, which are considered less fragile (compared to cells of higher eukaryotes); rendering them a popular choice for manufacturing operations. Moreover, incremental evolution