Month: December 2021

Myeloid Cell Targeting Therapies: Budding Therapy Against Cancer

The global cancer burden is increasing rapidly with over 19 million new cancer cases and 10 million deaths reported in the year 2020. Given the rising prevalence, researchers have made significant efforts in discovering new approaches for the treatment of oncological diseases. With several programs having entered the clinical stages, myeloid cell targeting therapies have

Regulatory T-cell Therapies: A Research Hotspot in the Field of Immunotherapy

Classification of Regulatory T-Cell Therapies The Regulatory T-Cell Therapies (Tregs) are a mature subpopulation of T-cells that play a critical role in mediating immunological tolerance to self-antigens and suppress immune responses that are harmful to the host, thereby, enabling homeostasis. These mainly develop in thymus from CD4+ thymocytes and are mainly of three types: natural

Site Management Organizations (SMOs): A Trending Term in the Clinical Trial Domain

Innovators in the pharmaceutical industry are constantly developing ways to improve the process of conducting clinical trials and managing research sites. Amidst other alternatives, outsourcing various trial operations to a specialized service provider, such as site management organizations (SMOs), has emerged as a viable option for various developers. The advantages of engaging such specialized service

DNA DATA STORAGE: RESEARCH LANDSCAPE AND FUTURE PROSPECTS

DNA data storage involves encoding and decoding binary data to and from synthesized strands of DNA. It offers generous, long-lasting, and stable data storage solution with orders of magnitude relatively higher than current storage mediums. Owing to the numerous benefits offered by DNA data storage as compared to other mediums, it is anticipated that this

HER2 Targeting Therapies Market: A Deeper Look into Therapy Developer Landscape and Future Opportunities

The epidermal growth factor receptor (EGFR is a tumor resistance biomarker which plays an essential role in the differentiation and proliferation upon activation through the binding of one of its ligands. A non-ligand-binding member of EGFR family, HER2 exerts its activity through heterodimerisation along with its other family members. HER2 is a transmembrane growth factor

THE RISING REALM: BIOPRESERVATION MEDIA INDUSTRY

Biopreservation is the exclusive biological approach designated for the preservation of cells, tissues and organs ex-vivo for the purpose of storage, shipment and transportation. Biopreservation media is one of the most crucial entity in conferring effectiveness. The selection of the type of media depends upon the considerable time duration desired for the storage, type of

Cell and Gene Therapy Bioassay – A Prerequisite for the ATMPs Development

Bioassay – A Prerequisite for the Cell and Gene Therapy Development Over the past few years, investigational new drug (IND) filings for cell and gene therapy product have significantly increased. In fact, from year 2016 to 2020 more than 300 IND filing for cell and gene therapy product have been recorded, indicating that several developers