Month: March 2022

Continuous Manufacturing: Meeting the Demand for Drugs and API

Over the last few decades, the pharmaceutical contract manufacturing market has been using batch processes for production of pharmaceutical products, which is a multi-phase process. However, the surge in the demand for drugs due to COVID-19 has led the pharmaceutical industry to shift on to a more agile and flexible technique- continuous manufacturing, which is

Metabolomics Testing: An Emerging Tool in Clinical Research

Scientific fields involved in high throughput measurement of biological molecules are referred with the suffix-omics including, nutrigenomics, transcriptomics, genomics, proteomics and metabolomics testing. Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. Likewise, metabolomics testing involves the study of by products of metabolism.

Subcutaneous Drugs: The Unmet Need in the Pharma Space

Over the years, the incidence and prevalence of chronic diseases, have increased significantly. Presently, the recommended treatment options for such clinical conditions are mostly biologics, which need to be administered via parenteral routes to ensure maximum therapeutic benefit. Given the inherent requirement for frequent medication, patients suffering from such long-lasting clinical conditions generally end up

Exosome Companies: In-depth Look into Service Providers Market

Over the years, applications of exosomes in therapeutics have undergone an evolutionary change, in terms of cost of research, technology used, and duration of the study. Moreover, various exosome companies have entered into collaborations in order to advance their innovations and offer specialized research expertise, services and technologies. In order to promote the use of

Pharmaceutical Excipients – Current Scenario and Future Trends

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical products are currently

Exosomes: A Trending Term in Therapeutic Domain

Exosome Therapy has been of great interest in the recent years due to the discovery of their potential in so many research and analytic procedures. Exosomes are known to have some unique functions, such as their ability to alter recipient cell bioactivities, acting like intercellular messengers and also having therapeutic potential in disease diagnostics as

Pharmaceutical Excipient Market: Current Scenario and the Future

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines, and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical excipient products are

Complement Therapeutics: Treating Complement-Related Diseases

Complement System:  Key Component of Complement Therapeutics Complement system was discovered in 19th century as a part of immune system responsible for tissue repair and homeostasis, thereby providing first line of defense against multiple infections. This complete process is in association with a complex and highly regulated assembly of proteins which involve several soluble and

Next Generation Therapeutics: Novel Therapies for Rare Diseases

Since the approval of Soliris® in 2007, an anti-C5 antibody, the field of complement drug discovery has gained significant attention. Currently, nine complement therapeutics are commercially available, while around 190 molecules are under development for various disease indications. Some of the complement therapeutics, namely Berinert®, Cinryze®, ORLADEYO®, Ruconest® and TAKHZYRO® were approved for the treatment

Peptide Pills: Addressing Key Unmet Needs Across Diseases

Orally administrable protein / peptide pills offer several advantages including, effective treatment of numerous clinical conditions and degenerative disorders. Interestingly, recent advances in this domain have led to the development of several treatment strategies that, according to developers, exhibit the necessary capabilities to overcome challenges posed by traditional oral formulations  and peptide pills. One of the

Intranasal Drugs: An Alternate Route of Administration

The intranasal drugs delivery is widely accepted as effective and non-invasive option for the local and systemic delivery of several types of active pharmaceutical ingredients (API). Majority of such formulations are designed to treat chronic obstructive pulmonary disorders (COPD), asthma and other respiratory diseases. Interestingly, over the past few years, drug developers focused on non-respiratory