Tag: Market Research Report

May 2, 2022

Plant Host Systems: A Novel Advancement in Protein Expression

By Yuveena Singh Plant Host Systems 0 Comments

Roots Analysis Blog

In the past few years, plants have been gaining a rapid traction, involving genetic modification and expression of new genes in plant host cells. Owing to significant advantages over conventional expression systems, such as low production costs, product safety, and ease of scaling up, plants are being widely recognized as a potential platform for the

March 25, 2022

Metabolomics: An Emerging yet Powerful Tool in Clinical Research and Development

By Jayita Sood Metabolomics 0 Comments

Scientific fields involved in high throughput measurement of biological molecules are referred with the suffix-omics including, transcriptomics, genomics, proteomics and metabolomics. Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. Likewise, metabolomics refers to the study of byproducts of metabolism. Although, metabolomics is

March 14, 2022

Biopharmaceutical Excipient Manufacturing – Current Scenario and Future Trends

By Arun Gupta Biopharmaceutical 0 Comments

Roots Analysis Blog

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical products are currently

October 28, 2021

Sustainable Packaging: Paramount for Pharmaceutical Sector

By Nobel Dhingra Pharmaceutical Packaging, SUSTAINABLE PACKAGING 0 Comments

Sustainable Packaging in pharmaceutical industry plays a crucial role in ensuring the sterility and quality of a drug product, while it also provides information related to its identity and, in certain cases, dosing instructions. Pharmaceutical packaging is typically carried out under Packagingcontrolled conditions; specifically, for therapeutics that are designed for parenteral administration, fill / finish

October 26, 2021

Alzheimer’s Disease and Its Evolving Market

By Sunidhi Thakur Alzheimer's Disease, Alzheimer's Pipeline, Alzheimer’s Disease 0 Comments

Alzheimer’s disease is a progressive neurological disorder characterized by the death of brain cells, eventually leading to memory loss, cognitive dysfunction and dementia. Accounting for 60-70% cases of dementia, Alzheimer’s disease is known to be the sixth leading cause of death in the US. Presently, more than 6 million Americans of all ages are living

October 25, 2021

Cell Therapy Packaging – Importance and Future Perspective

By Shivangi Anand Cell Therapy, Pharmaceutical Packaging 0 Comments

Over the years, the pharmaceutical industry has witnessed several advancements in drug development. It has gradually shifted from a one-drug treats all model to a more personalized approach of treatment, which involves the use of personalized cell therapies for various disease indications. This shift has led to an evident change in the pharmaceutical packaging domain

October 22, 2021

Progressive Supranuclear Palsy (PSP): A Tough Nut to Crack

By Ishita Nanda Supranuclear Palsy 0 Comments

Since John Steele, John Richardson, and Jerzy Olszewski first described Progressive Supranuclear Palsy (PSP) in 1964, the neuroscience community has been on the lookout to find a “miracle molecule” or an “elixir” that can cure patients diagnosed with this debilitating disease. With more than 2,000 research studies published so far, the domain has garnered significant

September 27, 2021

Bioprocess Automation: A Step Towards Digital Transformation

By Ridhima Gupta BIOPROCESS AUTOMATION 0 Comments

In the era of digitalization where the world is looking forward towards automating their manufacturing process, the bioprocess industry took a while to adopt the automation technology. The biopharmaceutical industry came across several obstacles while adopting the automated technology. Examples of which include, complexity of the processes and delicacy of the living cells and organisms

September 2, 2021

Clinical Trial Planning and Design Services Market: What Does the Future Hold?

By Bhavishya Bhardwaj CLINICAL TRIAL PLANNING, Clinical Trials, virtual clinical trials 0 Comments

Rootsanalysis Blog

Over the years, clinical research has undergone an evolutionary change, in terms of cost of research, technology used, and duration of the study. It is worth highlighting that clinical research involves two major steps, namely study design and study reporting. Further, study design involves three key steps, theoretical design, data collection design and statistical analysis

June 29, 2021

Target Protein Degradation – Transformative Approach to Selectively Eliminate Disease-Causing Protein

By Nancy Kapila Target Protein Degradation 0 Comments

Targeted protein degradation is an emerging therapeutic modality that has the potential to enable the treatment of difficult-to-treat diseases. While conventional medicines, such as small molecule inhibitors and monoclonal antibodies, address fewer than 20% of the proteome, TPD offers a unique means to tap into the rest of the vast, unexplored proteome. Through TPD, a

June 22, 2021

Nothing Ventured, Nothing Gain: Bringing to Light The Continuous Manufacturing Equipment Providers

By Shivangi Anand BIOMANUFACTURING, Contract Manufacturing, Manufacturing, Microbial Manufacturing 0 Comments

Over the years, several industries have implemented evolutionary changes in their respective manufacturing processes. One to the most rewarding advancements in this direction, is process automation. In pharmaceutical manufacturing, the automation of various aspects of the production process has led to the establishment of the continuous manufacturing paradigm. However, the transition to continuous manufacturing is

June 21, 2021

Polycystic Ovary Syndrome (PCOS)

By Nancy Kapila Polycystic Ovary Syndrome 2 Comments

women's digital health

Polycystic Ovary Syndrome is a condition in which the ovaries produce abnormal amount of androgens (males sex hormones), higher than the amount usually present in a woman with normal ovaries. The ovaries develop fluid filled sacs, known as follicles, which contain an immature egg. However, in polycystic ovary syndrome, none of the eggs mature and

June 7, 2021

Immunocytokines – The Power of Fusion Proteins

By Ishita Nanda Immunocytokines, Market Research, Proteins 1 Comment

Cancer is one of the leading causes of death worldwide, accounting for an estimated 0.6 million deaths in 2020, in the US alone. The World Health Organization has estimated the number of new cancer cases to rise by 70%, worldwide, over the next 20 years. It is a well-known fact that the conventional treatment options,

October 14, 2020

3D Cell Cultures: Rejuvenation amidst COVID-19

By Abhishek Dogra 3D Cell, 3D Cell Cultures, COVID-19, Market Research 1 Comment

As per the experts, one of the key reasons for the failure of therapeutic candidates in clinical trials is the use of conventional 2-dimensional (2D) cell culture systems in early research studies. The 2D systems are severely limited in a number of aspects. For instance, only 50% of the cell surface is exposed to the

October 13, 2020

Digital Therapeutics: Key Concepts and Regulations to Tackle COVID-19 Pandemic

By Yash Kumar COVID-19, Digital Therapeutics, Therapeutics, therapeutics market 1 Comment

Digital Therapeutics: Key Concepts and Regulations to Tackle COVID-19 Pandemic

Digital therapeutics are clinically validated applications / software / online programs that have demonstrated the capability to facilitate positive outcomes when used in the prevention / treatment / management of diseases / clinical conditions. These therapeutics are designed to engage patients in personalized treatment or disease prevention programs, through mediating behavioral or psychological modifications, providing

October 12, 2020

Inhaled and Intranasal Drug Delivery: A Deeper Look into Service Providers Landscape

By Ankita Kashyap Inhaled and Intranasal Drug Delivery, Market Research, Pharmaceuticals, Service Providers 1 Comment

Inhaled and Intranasal Products: Contract Service Providers Market

The techniques used for the drug delivery are found to be have an enormous impact on the efficacy of the treatment. In fact, the slow progression of the efficacy, has suggested the need of different approaches for the effective delivery of drug to the target area, along with the optimal bioavailability. Over the years, several

October 7, 2020

Targeted Drug Delivery Devices: An Attractive Option for Improving the Efficacy of Biologics

By Gaurav Chaudhary Biologics, Drug Delivery, Medical Device, Medical Devices and Technology 1 Comment

Targeted Drug Delivery Devices: An Attractive Option for Improving the Efficacy of Biologics

The gradual shift of healthcare industry towards the development of biologics is a well-known fact. Owing to this shift, there are over 1,000 cell and gene therapies which are being developed for the treatment of various disorders, majority of them being oncological disorders, cardiovascular disorders and neurological disorders. Additionally, over the last decade, multiple immunotherapies

September 17, 2020

Single-Use Bioreactors on Rescue for COVID-19 Research

By Sayoni Banerjee Bioreactors, COVID-19 1 Comment

The development of single-use bioreactors started nearly 40 years ago in 1980s. It was around this time that the bio-processors began to use plastic film bags to culture cells, which were initially designed for food storage and culture media containment. Moreover, incremental evolution of the concept of disposable technologies have facilitated various advancements in development

September 8, 2020

Nuclear Medicines And Radiopharmaceuticals: Redefining The Use Of Radioactivity In Modern Day Healthcare

By Gaurav Chaudhary RADIOPHARMACEUTICALS 1 Comment

Fostered by partnerships between national laboratories, academia, and the pharmaceutical industry, the field of nuclear medicines and radiopharmaceuticals has evolved over the past few decades, in parallel with advances in imaging instrumentation, radionuclide production, and radiopharmaceutical development. Nuclear reactors and particle accelerators are presently used to produce a wide array of radionuclides for diagnostic and

September 7, 2020

Will the Renascence of Microbial Manufacturing be Impacted by the Pandemic?

By Simriti Gupta Contract Manufacturing, Microbial Manufacturing 1 Comment

Since the discovery of recombinant DNA technology, several types of microbes have been established as a versatile biomolecule expression system. This can be attributed to the ease of handling of microbial cell lines, which are considered less fragile (compared to cells of higher eukaryotes); rendering them a popular choice for manufacturing operations. Moreover, incremental evolution

July 31, 2020

Outsourcing: An Attractive Option For Antibody Production

By Simriti Gupta Market Research, therapeutics market 1 Comment

In recent years, contract manufacturers have become an integral part of the overall biopharmaceutical market. This trend is also gaining popularity within the antibody therapeutics market, as developers are increasingly outsourcing their antibody production requirements to contract service providers. This can be attributed to the fact that employing such third-party service providers offers various advantages,

July 28, 2020

Large Volume Wearable Injectors: A breakthrough to simplify Chronic Disease Management

By Ishita Nanda Injectors, Injectors Market 1 Comment

The last few years have witnessed a rising incidence of chronic illnesses across the globe. Long term clinical conditions, such as neurological disorders, cardiovascular disorders, chronic pain and oncological disorders, have been shown to impose a significant burden on the modern healthcare system and those who suffer from such diseases. It is reported that about

July 27, 2020

Significant Potential of Gut Flora: Human Microbiome

By Nancy Kapila Human Microbiome 1 Comment

Human Microbiome Therapies are Viable Alternatives to Antibiotics, with Substantial Therapeutic Potential The term microorganisms was perceived to be synonymous to harmful, disease causing agents, until the discovery of certain beneficial microbial colonies in the human system. Currently, humans and a variety of species of bacteria, yeast and protozoa, are known to co-exist in mutually

July 23, 2020

The Evolving Dynamics of Large Volume Wearable Injectors Market

By Ishita Nanda Injectors, Injectors Market 1 Comment

The field of self-injection devices has witnessed a lot of innovation in the recent years. Specifically, , large volume wearable injectors are certainly a boon due to their ability to address challenges associated with the administration of high volume formulations, viscous drug solutions and cater to frequent dosing requirements of patients suffering from chronic health

July 9, 2020

Fill / Finish Services Industry: Impact of the Swelling Biopharmaceutical Pipelines

By Gaurav Chaudhary Biopharmaceutical, Biotech 1 Comment

Biopharmaceuticals represent the most rapidly growing and high-value segment of the pharmaceutical industry. Growing at an annualized rate of ~12%, the industry stands tall with more than 5,000 biologics in development and over 300 FDA approved biologics, since 2002. Biologic drug development is characterized by high quality standards and a rapidly growing demand for novel

July 8, 2020

In Vitro ADME Testing Services: Emerging Opportunities for Service Providers

By Gaurav Chaudhary Market Research, Testing Services 0 Comments

According to the US Food and Drug Administration (USFDA), less than 10% of investigational new drug (IND) candidates progress beyond the submission of a new drug application (NDA); this implies that majority of the drug / therapy candidates fail to reach the market owing to unacceptable safety and efficacy profiles and the problems associated with

July 8, 2020

Increasing Prevalence of Chronic Diseases- Driving the Demand for Self-Administration Devices, Like Autoinjectors

By Gaurav Chaudhary Autoinjectors, Drug Adherence, Medical Device, Medical Devices and Technology, Therapeutics 0 Comments

Over the last decade, autoinjectors have emerged as a promising therapeutic commodity for safe administration of parenteral therapies. Patients who suffer from chronic diseases, such as diabetes, rheumatoid arthritis and multiple sclerosis, often require frequent dosing of medication which poses significant inconvenience to them for visiting proper healthcare centers. Hence, autoinjector devices enable such patients

July 3, 2020

Peptide APIs – A Deeper Look Into Contract Manufacturing Market

By Simriti Gupta Contract Manufacturing, Manufacturing 1 Comment

The recent years have portrayed the renaissance of peptide APIs, as pharma industry has once again turned its attention towards the potential of therapeutic peptides. Adoption of peptides as therapeutic agents have side-lined some of the earlier concerns associated with them, such as bioavailability, and has led to manufacturing of high-quality peptides in a larger

July 3, 2020

Increasing Rate of Drug Failure has Prompted the Drug Developers to Rely on CROs offering In Vitro ADME Testing Services for their Outsourcing Requirements

By Gaurav Chaudhary ADME Testing, Drug Discovery 1 Comment

It is important to note that the process of drug discovery is extremely demanding, both in terms of capital and time. In fact, the overall amount spent on R&D initiatives in the pharmaceutical / biotechnology sector has increased from around USD 128 billion in 2008 to USD 165 billion in 2018. Moreover, only a small

June 25, 2020

Targeted Protein Degradation is Anticipated to Become a Major Therapeutic Modality in the Coming Decade

By Gaurav Chaudhary Protein Degradation, Therapeutics 1 Comment

The targeted protein degradation approach is believed to possess the potential to unlock the undruggable proteome, which was traditionally considered to be inaccessible. Compared to conventional inhibition strategies, degradation offers several benefits, which include the opportunity to completely remove aberrant proteins and associated systemic malfunctions. As a result, targeted protein degradation-based therapeutics have generated enthusiasm

June 23, 2020

Cell Therapy: A Potential Treatment for COVID-19?

By Simriti Gupta Cell Therapy, COVID-19 1 Comment

With the success of first vaccine to reach phase I clinical trial and turning out to be safe, well-tolerated, and capable of generating an immune response against the virus in humans, a lot of hope has been created with this vaccine. However, the research is still ongoing to develop novel therapeutic treatments that could aid

June 22, 2020

In Silico / Computer-Aided Drug Discovery Service Providers for Large Molecules

By Nancy Kapila Drug Discovery 1 Comment

Over time, the complexities associated with drug discovery have increased, especially in case of large molecule drugs, which are inherently more complex than conventional small molecules. As a result, an increase in the overall research and development (R&D) expenditure in the pharmaceutical / biotechnology sector has been witnessed. In addition to the complexities involved, the

June 22, 2020

Computational / In Silico Drug Discovery: A Boon in Disguise for Faster Drug Discovery Operations Amidst COVID-19

By Gaurav Chaudhary COVID-19, Drug Discovery 1 Comment

The COVID-19 pandemic is predicted to throw the global economy into recession, with loss of trillions of dollars. The pharmaceutical industry cannot escape the brunt of the circumstances as well. In fact, according to a survey, 95% of healthcare industry professionals are worried about the impact the pandemic is likely to have on the industry. So far,

June 18, 2020

Liquid Biopsy – The Beginning of a New Era in Cancer Diagnostics

By Ishita Nanda Cancer, Liquid Biopsy 1 Comment

Cancer is known to be one of the leading causes of death worldwide. In 2019, 0.6 million deaths due to cancer are estimated in the US alone. Moreover, the World Health Organization has estimated the number of new cancer cases to rise by 70% over the next 20 years. One of the primary reasons for

June 18, 2020

Next Generation Immune Checkpoint Inhibitors and Stimulators: Another Big Opportunity

By Ishita Nanda cancer therapeutics, Therapeutics 1 Comment

There is an urgent unmet need for developing innovative and effective cancer therapeutics for the treatment of patients with late-stage and refractory cancer. Amidst the widespread initiatives to develop more targeted anti-cancer therapies, immune checkpoint inhibitors emerged as a highly specific and potent option to eradicate tumor cells with minimal side effects. Once the body

June 17, 2020

Outsourcing has become a popular trend in ophthalmic drug development domai

By Gaurav Chaudhary Contract Manufacturing, Ophthalmic Drugs 1 Comment

Ophthalmic Drugs Contract Manufacturing Market

Owing to various reasons, such as growing manufacturing demand, need for specialized facilities, equipment and operational expertise, and high costs of development associated with certain drugs / therapies, a number of innovator companies have demonstrated a preference to outsource certain aspects of ophthalmic drug development and production operations to contract service providers. Over 240 companies

June 17, 2020

Microbiome-based Live Biotherapeutics Contract Manufacturing: Rising Opportunities for Specialized CMOs / CDMOs

By Gaurav Chaudhary Contract Manufacturing, Microbiome Research 1 Comment

What is the current development pipeline of microbiome-based live biotherapeutics? With over 85 products under preclinical and clinical development, the current development pipeline of microbiome-based live biotherapeutics has several promising candidates, which are anticipated to get commercialized over the next few years. Hence, the demand for R&D and manufacturing services for such products is anticipated

June 11, 2020

RISE OF ANTIBODY DRUG CONJUGATES WITH THE RECENT APPROVALS

By Ankita Kashyap Antibody Drug, Healthcare, Pharmaceuticals 1 Comment

RISE OF ANTIBODY DRUG CONJUGATES WITH THE RECENT APPROVALS

Antibody drug conjugates (ADCs) have captured the attention of both large and small pharmaceutical companies, and academic / research institutions, for more than a decade. For the past few years, several failures of clinical trials were blamed for the lack of interest of some companies in this therapeutic approach. However, after a decade-long dribble of

May 25, 2020

Response to COVID-19 Pandemic with Oligonucleotides

By Gaurav Chaudhary COVID-19, Covid19, Oligonucleotides 1 Comment

Never before, scientists say, the universal community of researchers have put a halt to all other ongoing research and have urgently focused towards swiftly evolving health emergency. In the past few months, scientists have been repurposing their research efforts towards contributing to the global effort in response to COVID-19 pandemic. For the purpose of mitigating

May 19, 2020

Neoantigen Targeted Therapies Pave the Way to Personalized Anti-cancer Therapy

By Ishita Nanda Anti-cancer, Anti-cancer Therapy, Therapies 1 Comment

Neoantigen Targeted Therapies Pave the Way to Personalized Anti-cancer Therapy There is an urgent unmet need for developing innovative and effective cancer therapeutics for the treatment of patients with late-stage and refractory cancer. Amidst the widespread initiatives to develop more targeted anti-cancer therapies, immunotherapy emerged as a highly specific and potent option to eradicate tumor

May 15, 2020

Neoantigen Targeted Therapies – A Potential Weapon in the Fight against Cancer

By Ishita Nanda Cancer, Therapies 1 Comment

Cancer – one of the most feared and dreaded diseases. It is known to be one of the leading causes of death worldwide, accounting for 0.6 million deaths in 2018, in the US alone. The World Health Organization has estimated the number of new cancer cases, reported across the globe, to rise by 70% over

April 2, 2020

Fragment-based Drug Discovery – A Boon in Disguise to get a Breakthrough Drug Against Covid-19

By Ishita Nanda Drug Discovery 0 Comments

RootsAnalysis Blog

With over 855,000 cases and 42,000 deaths, the novel coronavirus has taken its toll on humanity. The pandemic is predicted to throw the global economy into recession, with loss of trillions of dollars. The pharmaceutical industry cannot escape the brunt of the circumstances as well. In fact, according to a survey, 95% of healthcare industry

April 2, 2020

Coronavirus: Stem Cell Contract Manufacturing Demand to Surge Rapidly

By Ishita Nanda Coronavirus, Stem Cells 1 Comment

Roots Analysis Blog

As is the case with numerous pharmaceutical companies who have been racing to find a potential cure for the patients suffering from infection with Corornavirus, the stem cell industry has been on an outlook to identify stem cell therapies which can treat the disease and / or its symptoms. Athersys is developing a possible therapy

October 9, 2019

Synthetic Lethality Market: Riding on the ESMO 2019 Success of PARP Inhibitors

By Gaurav Chaudhary Synthetic Lethality 0 Comments

Synthetic Lethality Market: Riding on the ESMO 2019 Success of PARP Inhibitors

After a strong showdown at ESMO 2019, both GSK and AstraZeneca have reignited the fight of small molecule anti-cancer drugs against the industry’s brawny immunotherapy push. Leading this fight is poly(ADP-ribose) polymerase (PARP) inhibitor, one of the leading synthetic lethality targets. These better than expected results at ESMO further validate the potential of synthetic lethality

October 18, 2017

Antibody Discovery: The Rise of Services and Platform Providers

By Arun Gupta Antibody Discovery 0 Comments

The rising demand for personalized medicines to provide targeted treatment options has encouraged pharmaceutical companies to shift their focus from small molecules to discovery and development of biologics, particularly antibody-based therapeutics. The ‘Antibody Discovery: Services and Platforms, 2017-2027’ report provides an extensive study on the current market landscape and future outlook of the antibody discovery service and

August 31, 2017

Bolu Injectors: The Goldrush Continues

By Arun Gupta Injectors 0 Comments

The large scale adoption of prefilled syringes demonstrated the growing interest in the concept of such convenient drug delivery systems. Large volume wearable injectors (also termed as bolus injectors) are advanced versions of the existing self-injection devices. The ‘Large Volume Wearable Injectors Market (3rd Edition), 2017-2027′ report features an extensive study of the current landscape and the