Category: Pharmaceuticals

Pain can be defined as a feeling of physical, emotional, or mental suffering caused by injury, illness, or other factors. It is a common medical condition and symptom that prompts individuals to seek medical attention worldwide. Pain management industry has been witnessing a remarkable upgrade. Effective pain management is crucial for improving patient outcomes and

Pain is a multifaceted experience that can have various underlying causes, including neurophysiological, biochemical, psychological, cognitive, and environmental factors. Different medical experts, such as neurosurgeons and psychologists, may perceive and interpret pain differently based on their respective areas of expertise. A neurosurgeon may view pain as a neuroanatomical or neurophysiological event, while a psychologist may

In order to effectively combat the problems related to counterfeit medicines, several companies have come up with innovative technologies to provide the necessary tools to manufacturers, healthcare professionals and patients to authenticate pharmaceutical products. Anti-counterfeiting technologies technologies can be broadly classified under two categories, namely Authentication Technologies and Track & Trace Technologies. Authentication technologies are

Shares of Zealand Pharma experienced a significant surge, jumping 16% as the market opened on Monday, following the release of groundbreaking phase II trial results for an experimental obesity treatment being developed in collaboration with Boehringer Ingelheim. This surge came as the trial testing the drug survodutide for the treatment of fatty liver, specifically metabolic

The inherent expertise of CMOs and CDMOs is believed to be capable of enabling reduction in the time-to-market a product, significant cost-benefits, as well as access to larger production capacities and novel technologies.  It is worth mentioning that there has been substantial merger and acquisition activity in the pharma CMO market in the past few

The growing pipeline of monoclonal antibodies, vaccines, enzymes, biosimilars and other therapeutic proteins have created an ever- increasing demand for highly- productive and stable cell lines. Many of the recombinant biotherapeutic products, produced in cellular systems, have been translated into commercial successes; these include ALPROLIX®, ELOCTATE® and ELAPRASE®.  Given their impact on the overall quality

For developing an improved understanding of the interactions of individual cells within their microenvironment, advanced molecular probing solutions are being used by researchers across the globe. In this context, high-throughput single cell technologies, have emerged as a powerful analytical technique for studying individual cells, enabling researchers to study gene expression at single cell resolution. Single

With the ongoing pandemic of COVID-19, there is long wait for the vaccine to be approved. Even after the vaccine gets approved, there is no assurance of the complete eradication of virus. There will still be percentage of people who contract the illness. Therefore, it is very important to trace and detect the treatments in

While the definition of real world evidence (RWE) is still evolving, most proponents associate it with data that is derived from medical practice among heterogeneous sets of patients in the real world setting. It is the integration of data gathered from various sources, such as EHRs, medical charts, patient claims and billing activities, product and

The techniques used for the drug delivery are found to be have an enormous impact on the efficacy of the treatment. In fact, the slow progression of the efficacy, has suggested the need of different approaches for the effective delivery of drug (such as intranasal drugs) to the target area, along with the optimal bioavailability.

Antibody-Drug Conjugates (ADCs) have captured the attention of both large and small pharmaceutical companies, and academic / research institutions, engaged in the ADC contract manufacturing market. For the past few years, several failures of clinical trials were blamed for the lack of interest of some companies in this therapeutic approach. However, after a decade-long dribble

The ongoing COVID-19 crisis has put the pharmaceutical manufacturing supply chain under close scrutiny. The overdependence of the US on China and India to meet its API demand has been the talk of the town. However, with the number of infected cases in the US surpassing that of China, the focus has shifted from discussing

To err is human, to rectify divine, this irony perhaps holds truer for cannabis than any other domain. After using cannabis in multiple forms for at least 10,000 years, a series of events, including spread of misinformation, anti-Mexican sentiment and fear led to the ban of nature a.k.a. cannabis. The US implemented Marijuana Tax Act

It is not very common to hear venture capital firms back competitors in the same week. It happened yesterday with Nurix announcing a USD 120 million backing yesterday, immediately after Kymera had grabbed an almost similar amount earlier this week. This does tell us something about the field of Targeted Protein Degradation! Read on. How

Targeted protein degradation (TPD), as a mechanism to target previously untreatable conditions, was one of the key highlights of the year 2019. In an article published late last year titled targeted protein degradation market, we discussed, in detail, the epic rise in the popularity of TPD. What is TPD? TPD is an emerging modality that

Although the healthcare industry relies on the patient to take medications responsibly; in 2017, close to 18 million individuals were reported to have misused prescription drugs, in the US. In fact, data from a National Survey on Drug Use and Health conducted in the same year, showed that an estimated 2 million Americans misused prescription

The ready to use of pharmaceutical primary packaging has emerged as a promising alternative to conventional primary packaging, adding significant value to streamline pharmaceutical fill / finish operations. These packaging components eliminate multiple steps in the overall fill finish manufacturing (mainly washing, sterilizing and preparing containers), thereby, helping improve operational efficiencies in compliance to existing 

During drug product manufacturing and fill / finish, it is important to consider not only the impurity profiles of the drugs, but also identify potential sources of contamination in the containers / packaging material used. due to high variability in the type of impurities (organic (volatile, non-volatile or semi- volatile compounds) or inorganic (metals or

Given the increase in complexity of the drug discovery process, the overall R&D spending in the pharmaceutical contract manufacturing / biotechnology sector has grown from around USD 128 billion in 2008 to USD 158 billion in 2017. As a result, the industry is currently under tremendous pressure not only to meet the expectations of a

Since the introduction of the automatic injector (autoinjectors) device in 1980s, their numerous benefits, such as ease-of-use, reduced chances of dosing errors, integrated safety mechanisms, and almost negligible risk of needlestick injuries, have been widely recognized among consumers and healthcare service providers. Automatic injector are also considered to be potential life cycle management tool. Drugs

Low drug bioavailability is one of the primary concerns associated with marketed medications; in fact, various studies indicate that around 40% of available drugs are poorly bioavailable / soluble. As the drug developers shift their focus towards development of lipophilic drug compounds, the issue with aqueous solubility / drug bioavailability is likely to be increase

Spray drying, which is already established in the food and chemical sector, is also considered to be a rapid, cost-effective, and scalable process for the production of dry powder formulations of pharmacological material. Owing to characteristics, such as reproducibility and its continuous mode of operation, the technique has become very popular in the pharmaceutical contract

The first gene therapy, Gendicine®, was only approved in 2003 in China; since then, the domain has evolved significantly. The ‘Gene Therapy Market (2nd Edition), 2018-2030’ report provides an extensive study on the current market landscape of gene therapies, with a prime focus on gene augmentation based therapies and oncolytic viral therapies, featuring an elaborate discussion on

The current treatment landscape for back of the eye disorders is characterized by the presence of blockbuster novel ophthalmic drugs, such as Lucentis® and Eylea®, and various other therapeutic options. Despite the success of these therapies, their invasive mode of administration, high dosage frequency and other drug related side effects, are some of the drawbacks

The objective of the ongoing R&D in this domain is to develop novel CSC directed treatments that can combat complications, such as off-target toxicities and disease relapse, associated with the current standard of care treatments. The ‘Cancer Stem Cell Therapies Market, 2017-2030’ report examines the current landscape and the future outlook of the growing pipeline of products

While there are close to 200 ADCs in various stages of development, the market field is currently going through a gradual transition, shifting from relying on conventional technologies to newer approaches for generating ADCs. The ‘Antibody Drug Conjugates Market (4th Edition), 2017-2030’ report provides a comprehensive study on the current landscape of ADCs, featuring an elaborate discussion

Cross contamination and cell line misidentification are some of the major concerns associated with the use of cell lines. It has been estimated that a net loss of USD 28 billion is incurred every year on research that cannot be replicated due to the involvement of misidentified or contaminated cell lines in the US. To

Owing to their use in the manufacturing of biologics and biosimilars, and various application areas, such as drug screening, gene functional studies, cell-based assay development, diagnostics and tissue engineering, there is growing demand for different types of cell lines. The ‘Cell Line Development Services Market, 2017 – 2027’ report provides an extensive study of the rapidly growing market

The concept of immunotherapies dates back to the 18th century; however, since its inception, the field has evolved tremendously and is currently cited as one of the most rapidly growing segments of the pharmaceutical industry. Post the early success of immune checkpoint inhibitors, T-cell immunotherapy has emerged as another innovative and potent arm of this market.

The Centers for Disease Control and Prevention (CDC) estimates that over two million  people suffer from life threatening infections caused by drug resistant strains of bacteria every year, in the US. According to a report published in the UK, the global death toll due to the current ADR crisis is likely to reach as high as 10

When it comes to taking medicine, we usually have blind faith in what the Pharmaceutical hands us and consume it without a second thought. The thought that a prescription drug may be a fake medicine or even harmful does not generally cross our minds. However, the issue of fake medicine is more serious than we

The importance of the pharmaceutical industry as a global sector is undeniable. In 2014, pharmaceutical sales reached a milestone of USD 1 trillion. Apart from discovering and developing innovative healthcare solutions, pharmaceutical companies also need to market and promote their products to remain profitable. It is worth mentioning that the sales and distribution of pharmaceutical

India is en route to becoming a powerful and dynamic nation. Numerous initiatives undertaken by both the private and public sectors have been launched to revolutionize the way the nation operates. Prominent examples include the smart cities initiative, introduction of high speed trains, and the extensive efforts by the current Prime Minister, Mr. Narendra Modi,