Category: 3D Cell

The growing pipeline of monoclonal antibodies, vaccines, enzymes, biosimilars and other therapeutic proteins have created an ever- increasing demand for highly- productive and stable cell lines. Many of the recombinant biotherapeutic products, produced in cellular systems, have been translated into commercial successes; these include ALPROLIX®, ELOCTATE® and ELAPRASE®.  Given their impact on the overall quality

As per the experts, one of the key reasons for the failure of therapeutic candidates in clinical trials is the use of conventional 2-dimensional (2D) cell culture systems in early research studies. The 2D systems are severely limited in a number of aspects. For instance, only 50% of the cell surface is exposed to the

The use of advanced 3D cell culture techniques in in vitro studies is seen to have the capability to overcome several challenges associated with 2D systems. The ‘3D Cell Cultures: Products, Technologies and Key Application Areas (2nd Edition), 2017-2030’ report features an extensive study on the various scaffold-based and scaffold-free 3D culture systems. Some of