May 28, 2025

The Future of Autonomous Deliveries: Integrating Drones and Self-Driving Vehicles

By Ronit Sharma Logistics, Medical Drone Delivery  0 Comments

As technology is rapidly evolving, so is each sector related to it. The delivery management landscape is one such sector which is evolving at an astronomical pace. With technological advancements, shifting consumer expectations, and the global expansion of e-commerce acting as the fuel, delivery management software is destined to undergo significant transformations. In this blog,

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January 27, 2025

Radiopharmaceutical Manufacturing: A Multi-Disciplinary Endeavour for Medical Imaging and Interventional Treatment

By Jasmeet Bhalla RADIOPHARMACEUTICAL MANUFACTURING  0 Comments

Nuclear medicine is a medical specialty that involves the use of radionuclides or radioactive tracers in conjunction with highly specialized imaging instrumentation to detect the emissions in the body after oral, inhalation, or intravenous administration of radionuclides. A radioactive tracer is a drug that is composed of a short-lived medical isotope tightly attached to a

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January 27, 2025

Subcutaneous Biologics Market Analysis: Current Trends and Future Outlook

By Dakshita Dhawan Antibodies, Biologics  0 Comments

Over the years, the incidence and prevalence of chronic diseases, such as diabetes, multiple sclerosis and rheumatoid arthritis, have increased significantly. This has led to the growing research and development towards the development of biologics for therapy purpose. These biologics are generally administered through parenteral route of administration in order to ensure maximum therapeutic benefit.

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January 27, 2025

Key Trends in the Microbial CMO Market

By Ronit Sharma microbial, Microbial Manufacturing  0 Comments

Benefits offered by microbial manufacturing, such as low production costs and faster development timelines, have led many innovators to adopt microbial fermentation for next generation biologics, offering lucrative opportunities for microbial CMOs / CDMOs. Within microbial fermentation market, service providers presently claim to have most of the microbial production capacity, driving innovators to outsource their

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January 27, 2025

Emerging Trends in Protein Expression Systems: Growth Opportunities And Future Outlook

By Gurleen Kaur Protein Expression  0 Comments

Protein therapeutics have completely revolutionized the healthcare segment, greatly influencing the study and treatment of human diseases by conferring precise targeting ability to therapeutic modalities. Considering their vast potential, close to 50% of the top selling drugs in 2023 were protein therapeutics. Owing to the benefits of protein-based therapeutics, such as target specificity, biological compatibility,

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January 27, 2025

Building Tomorrow’s Therapies Today: The Evolution of Cell Therapy Manufacturing Process

By Ronit Sharma Cell Therapy Manufacturing  0 Comments

The American Society of Gene and Cell Therapy (ASGCT) defines cell therapy as a therapeutic modality that involves the administration of either normal or modified cells to patients for the treatment of various diseases. In this form of therapy, patients are injected with living and intact human cells that are deemed to be capable of

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September 10, 2024

Neurovascular Medical Device Companies: Driving A New Paradigm For Neurovascular Disorders Treatment

By Shreeya Agrawal Medical Device, neurovascular devices  0 Comments

Neurovascular disorders are recognized among the top five life-threatening conditions, accounting for approximately 15 million new cases and five million mortalities annually, across the globe. This increased incidence of neurovascular disorders can be attributed to other underlying pathological conditions, such as diabetes, hypertension and obesity along with poor lifestyle choices. Currently, several conventional approaches, such

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September 9, 2024

From Gene to Protein: The Journey of Protein Expression Technology

By Dhriti Gulati Proteins  0 Comments

Over the years, pharmaceutical companies have shifted their priorities from traditional interventions towards more advanced pharmacological strategies, such as protein therapeutics. It is worth highlighting that in 2023 alone, close to 20 protein-based drugs were approved for the treatment of myriad of disease indications including oncological and metabolic disorders. Further, $400 billion is the anticipated

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September 4, 2024

IVD Market: SWOT Analysis

By Gaurav Raj Diagnostics  0 Comments

The main purpose of in vitro diagnostic solutions is to perform non-invasive / minimally invasive test procedures in order to detect a variety of health conditions using samples, such as blood, tissue or urine. Such tests help to diagnose health conditions, monitor treatments, perform disease screening and aid in early diagnosis of diseases. The process

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August 31, 2024

Pain Management Industry: Current Landscape of Leading Device Developers And Upcoming Trends

By Prachi Bhalla Medical Device, Medical Devices and Technology, Pharmaceuticals  0 Comments

Pain can be defined as a feeling of physical, emotional, or mental suffering caused by injury, illness, or other factors. It is a common medical condition and symptom that prompts individuals to seek medical attention worldwide. Pain management industry has been witnessing a remarkable upgrade. Effective pain management is crucial for improving patient outcomes and

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August 30, 2024

Radiopharmaceutical Production Market: Current Landscape And Upcoming Trends

By Usama Firoz RADIOPHARMACEUTICALS  0 Comments

In the realm of modern medicine, nuclear medicine has emerged as a promising and advanced tool that can be used for the diagnosis and treatment of diseases. Nuclear medicine involves the use of radiopharmaceuticals or radiotracers in which radioisotopes are bound to biological molecules that can target specific organs, tissues, or cells within the human

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August 29, 2024

Robots in the Medical Field: Current Landscape and Upcoming Trends

By Prachi Bhalla Medical Robots Market, Robots  0 Comments

The two main categories of robots in the medical field include surgical robots and rehabilitation robots. The surgeries being performed with the assistance of robots are often termed robot-assisted surgeries. Robotic surgery allows surgeons / clinicians to perform complex medical procedures with higher precision and ease. Mostly, robotic surgery accounts for minimally invasive surgery which

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August 28, 2024

The Transformative Impact of Pain Relief Devices

By Prachi Bhalla Medical Device, Medical Devices and Technology, Pharmaceuticals  0 Comments

Pain is a multifaceted experience that can have various underlying causes, including neurophysiological, biochemical, psychological, cognitive, and environmental factors. Different medical experts, such as neurosurgeons and psychologists, may perceive and interpret pain differently based on their respective areas of expertise. A neurosurgeon may view pain as a neuroanatomical or neurophysiological event, while a psychologist may

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August 27, 2024

Radiopharmaceutical Manufacturing : A Multi-disciplinary Endeavour for Medical Imaging and Interventional Treatment

By Rupali Bhardwaj RADIOPHARMACEUTICALS, Uncategorized  0 Comments

Nuclear medicine is a medical specialty that involves the use of radionuclides or radioactive tracers in conjunction with highly specialized imaging instrumentation to detect the emissions in the body after oral, inhalation, or intravenous administration of radionuclides. A radioactive tracer is a drug that is composed of a short-lived medical isotope tightly attached to a

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August 26, 2024

Pioneering Sustainability: A Journey Through Milestones in Sustainable Packaging Industry

By Dakshita Dhawan Healthcare Packaging, Pharmaceutical Packaging, Pharmaceutical Secondary Packaging, SUSTAINABLE PACKAGING  0 Comments

In today’s global landscape, sustainability has emerged as a pivotal concern across various sectors including the pharmaceutical packaging industry. With mounting pressure to reduce the degrading impact on the environment posed due to conventional packaging materials, stakeholders engaged in the pharmaceutical sector have been compelled to reevaluate traditional practices and step into the sustainable packaging

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August 23, 2024

The Booming Potential of mRNA Technology

By Vaibhav Singh mRNA, mRNA Technology  0 Comments

In recent years, mRNA technology has rocked the world of medicine, making it possible to prevent and treat a vast array of diseases and disorders. Vaccinations in the past have always been either weak or inactive forms of a pathogen which was given to the body so that our immune system is trained to recognize

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August 16, 2024

Oncology Molecular Diagnostics Market: Solutions Driving Early Cancer Detection

By Gaurav Raj Diagnostics, Non-Invasive Diagnostics  0 Comments

Globally, cancer is one of the leading causes of death, however advancements in molecular diagnostics have enabled early detection and improved outcomes. Early detection of cancer is crucial as it improves the treatment process and increases the chances of survival. This article explores the role of molecular diagnostics in early cancer detection, highlighting the benefits

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August 15, 2024

Sustainable Pharmaceutical Packaging Market: The Need, Advantages and Drivers

By Dakshita Dhawan Healthcare Packaging, Pharmaceutical Packaging, Pharmaceutical Secondary Packaging, SUSTAINABLE PACKAGING  0 Comments

Packaging is the process of enclosing a product in a container in order to protect and store it. In the pharmaceutical industry, packaging plays a crucial role in ensuring the strength and integrity of a product. Further, the type of raw material utilized for packaging highly depends on the type of product / drug to

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August 14, 2024

Landscape of mRNA-Based Therapeutics and Vaccines: Growth Opportunities and Future Outlook

By Vaibhav Singh Uncategorized  0 Comments

Messenger ribonucleic acid (mRNA) is a type of single-stranded ribonucleic acid (RNA), which helps in transferring genetic information in order to produce proteins. The mRNA encoding instructions for protein synthesis are transferred from a strand of DNA to the ribosomes, where these instructions are translated and processed into functional proteins. mRNA-based therapeutics and vaccines have

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August 13, 2024

Synthetic Leather Industry – The Sustainable, Innovative Solution That Redefines Luxury Without Compromise

By Rishav Thakur Uncategorized  0 Comments

Synthetic leather industry is emerging as a game-changer in the world of materials. It is an alternative to genuine leather, offering a compelling balance between style and sustainability. Synthetic leather is made from innovative materials that are constantly evolving, caters to the growing demand for eco-conscious and animal-friendly options. Synthetic leather boasts impressive versatility, allowing

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August 12, 2024

Molecular Diagnostic Tests: The Unsung Hero of Precise Clinical Decision Making

By Gaurav Raj Diagnostics, Non-Invasive Diagnostics  0 Comments

Molecular diagnostic tests are advanced techniques and tools used to analyze biological markers in the genome and proteome. These diagnostic solutions are essential for detecting and monitoring diseases, identifying genetic abnormalities, and guiding personalized treatment plans. The primary technologies used in the molecular diagnostics domain include polymerase chain reaction, next-generation sequencing and microarrays. Molecular diagnostic

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August 2, 2024

GLP1 Receptor Agonist Market: Current Landscape, Growth Opportunities and Future Market Outlook

By Simran Kaur Non-Insulin Therapies Market, Uncategorized  0 Comments

GLP-1 receptor agonist market have captured the attention of both large and small pharmaceutical companies, for more than a decade. However, after a decade-long dribble of GLP-1 drugs and the recent approval of obesity drugs, the domain has gained significant attention. Currently, more than 10 GLP-1 receptor agonists are commercially available, while various molecules are

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August 1, 2024

Medical Robots Market: A Multi-Disciplinary Endeavour for Aiding Patients and Healthcare Professionals

By Prachi Bhalla Medical Robots Market, Robots  0 Comments

Medical robots are medical devices that are programmed to assist medical professionals in a variety of tasks, such as patient interaction, patient welfare assessment, operating in hazardous and emergency circumstances, data mining to enhance the efficiency of a pharmacy, and disinfection of hospital rooms. As a result, these robots are being utilized in medical robots

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July 31, 2024

Oncology Biomarkers: Current Landscape, Growth Opportunities and Future Market Outlook

By Simran Kaur ONCOLOGY BIOMARKERS, Uncategorized  0 Comments

Over the last couple of decades, the healthcare market has witnessed the entry of several advanced and effective treatment options for cancer; these include a variety of targeted therapies, immunotherapies and certain anti-cancer vaccines as well. However, clinical cancer research is still plagued by high failure rates, various drug / therapy-related limitations, and treatment-based adverse

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July 30, 2024

Artificial Intelligence in Wound Care: “A Paradigm Shift in Healthcare”

By Aanchal Chaudhary artificial intelligence, Healthcare  0 Comments

Before we dive into the details on artificial intelligence in wound care, it is important to go through some of the basiscs related to wound care. Wounds are injuries to the skin or underlying tissues that can be caused by cuts, scrapes, burns, or other forms of trauma. Further, wounds can vary in terms of

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July 29, 2024

Skincare Industry Trends

By Kumar Shagnick NOVEL DRUG  0 Comments

In 1967, renowned zoologist Desmond Morris quoted, “Flawless skin is the most universally desired human feature”. According to him, social convention dictates that the well-being of human health and fertility are indicative of an even-toned, clear skin with a radiant complexion. While cosmetic procedures can effectively target specific aging concerns like deep wrinkles, sagging skin,

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July 28, 2024

In Vitro Diagnostic Industry: A Review of The Unsung Hero of Precise Clinical Decision Making

By Gaurav Raj Diagnostics  0 Comments

In vitro diagnostic solutions are the behind-the-scenes hero of healthcare, quietly working to help diagnose and manage variety of health issues. The blog below includes information about these solutions, the latest trends in this market and how such solutions help to diagnose and detect disease conditions. In addition to the healthcare providers, the stakeholders in

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June 6, 2024

Injecting Innovation: The Rising Trend of Autoinjectors in Modern Medicine

By Simran Kaur Autoinjectors  0 Comments

Autoinjector are medical devices that enable the rapid and safe delivery of drugs through different administration routes. They are designed to offer patients a convenient and effective means of self-administering medications, particularly in emergency situations and chronic conditions (that require frequent injections). Further, various advancements, such as hidden or retractable needles (which mitigate the risk

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May 24, 2024

Autoinjector: Empowering The Healthcare Industry

By Simran Kaur Autoinjectors  0 Comments

In the dynamic landscape of the healthcare sector, the evolution of drug delivery systems plays a significant role in transforming the management of chronic diseases. Among the various innovations, self-injection devices (specifically autoinjector) have emerged as a promising solution. Autoinjector are self-injection devices that automatically insert the needle and deliver a particular amount of therapeutic

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May 23, 2024

Decoding Health – Unravelling the Power of Digital Biomarkers

By Simran Kaur Digital Biomarker  0 Comments

The evolution of the healthcare industry is being driven by advancements in technology and rising adoption of telemedicine & digital biomarker. With increasing digitization across the globe, the need for real-time data access, management and analysis of health data has gained remarkable importance. The growing use of wearable devices and mobile applications to monitor health

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May 22, 2024

Allogeneic Cell Therapies – An Emerging Modality in Therapeutics

By Simran Kaur Cell Therapies  0 Comments

Cell therapy refers to the introduction of active, healthy cells into a patient’s body in order to replace the damaged or previously compromised tissues. The cells used in the cell therapy can be from the patient’s own body (autologous) or from a donor (allogeneic). In allogeneic cell therapies, the cells are engineered (to elicit a

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May 21, 2024

The Power of Lipids: Enhancing Drug Delivery with Nanoparticles

By Simran Kaur Nanoparticles  0 Comments

Over the last decade, one of the major challenges faced by pharmaceutical companies across the globe is low drug solubility. In fact, it has been observed that around 40% of the pharmaceutical drugs approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the main causes of drug

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May 21, 2024

Protein Precision: “Harnessing Targeted Protein Degradation”

By Ajay Kumar Target Protein Degradation  0 Comments

Proteins are the chains of amino acids linked together in different combinations and perform a wide variety of functions. These are the vital structural component of cells, which help in cell functioning and regulation of building body tissues. However, continuous regulation of the cellular proteome is essential for maintaining the right balance of different proteins

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April 29, 2024

Rare Kidney Diseases: Exploring The Uncommon Rare Conditions

By Aanchal Chaudhary Chronic Kidney Disease, Rare Kidney Diseases  0 Comments

Rare kidney diseases are a group of conditions, with at least 150 different disorders falling into this category. Kidney disorders are known to have a serious impact on the general kidney function, often lowering its ability to filter out waste and fluids from the blood, maintaining blood pressure, hemoglobin levels and electrolyte balance. Kidney disorders

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April 15, 2024

Outsourcing Biologics Fill Finish Manufacturing : Streamlining the Production Process for Biopharmaceutical Companies

By Pemba Lahmo Fill-Finish Manufacturing  0 Comments

Biologics fill finish represent one of the fastest growing segments of the pharmaceutical industry. Over the years, these large molecules have demonstrated promising therapeutic outcomes in the treatment of myriad of chronic and challenging disorders, including autoimmune disorders, infectious diseases, genetic disorders, and oncological disorders. These complex entities, such as antibodies, antibody drug conjugates, cell

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March 27, 2024

Squamous Non Small Cell Lung Cancer Market: Current Scenario

By Simriti Gupta Cancer, CANCER MARKET, cancer therapeutics, Novel Cancer  0 Comments

Close to 1.8 million fatalities reported in 2020 were observed to be associated with lung cancer, which is believed to be one of the most aggressive forms of carcinoma, globally. One of the primary reasons for the high mortality rate associated with this condition is anticipated to be improper liquid biopsy, which eventually results in

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March 27, 2024

Remote Patient Monitoring System: A Paradigm Shift in Healthcare

By Arun Gupta Patient Monitoring  0 Comments

The development of the concept of remote patient monitoring system (RPM) started nearly 200 years ago in 1800s. However, it wasn’t until the introduction of cloud computing, that the domain evolved at a significant pace. In fact, remote patient monitoring system solutions are gradually being integrated into mainstream healthcare; specifically, during the COVID-19 induced lockdown,

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March 27, 2024

Pandemic Like Never Before – Continuous Manufacturing to the Rescue

By Pemba Lahmo Contract Manufacturing, Coronavirus, COVID-19  1 Comment

The coronavirus outbreak and the drop in economy that we are facing today is unlike anything that most of us have seen in our lifetime. The pandemic has threatened the whole world to such an extent that life has come to a standstill. In fact, the initial stage of lockdown featured the fragile nature of

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March 14, 2024

Antiviral Medications: An Unmet Requirement in Pharmaceuticals

By Arun Gupta antiviral drugs  0 Comments

Over the past few years, a number of antiviral drugs targeting a myriad of infectious diseases, including human immunodeficiency virus (HIV) infection, hepatitis, herpes simplex virus (HSV) infection, cytomegalovirus (CMV) infection, influenza, coronavirus infection (COVID-19) and others, have received approvals from various regulatory authorities, globally. However, it is important to note that, currently, the approved

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March 13, 2024

mRNA Technology: Transforming Medicine

By Simran Kaur mRNA  0 Comments

Messenger ribonucleic acid (mRNA) serves as a carrier of genetic instructions from DNA to the cell machinery for the production of proteins. mRNA technology plays a significant role in the development of therapeutic interventions, exemplified by the incredible success of COVID-19 vaccines (namely COMIRNATY and Spikevax). It holds promise in treating various autoimmune disorders, degenerative

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March 1, 2024

Anti-Counterfeiting Technologies in Healthcare

By Arun Gupta Anti-Counterfeiting, Pharmaceuticals  0 Comments

In order to effectively combat the problems related to counterfeit medicines, several companies have come up with innovative technologies to provide the necessary tools to manufacturers, healthcare professionals and patients to authenticate pharmaceutical products. Anti-counterfeiting technologies technologies can be broadly classified under two categories, namely Authentication Technologies and Track & Trace Technologies. Authentication technologies are

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March 1, 2024

Zealand Pharma Stock Surge on Liver Disease Drug Trial Data

By Pemba Lahmo Pharmaceuticals  0 Comments

Shares of Zealand Pharma experienced a significant surge, jumping 16% as the market opened on Monday, following the release of groundbreaking phase II trial results for an experimental obesity treatment being developed in collaboration with Boehringer Ingelheim. This surge came as the trial testing the drug survodutide for the treatment of fatty liver, specifically metabolic

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February 29, 2024

ADCs Pipeline Update: Sutro Biopharma Presents Encouraging Data in Patients with Advanced Ovarian Cancer

By Gaurav Chaudhary ADCs Pipeline  0 Comments

Sutro Biopharma, a California based, clinical-stage company, announced initial safety data in ovarian cancer patients from its ongoing phase I study (NCT03748186) of STRO-002. The drug is a folate receptor alpha (FolRα)-targeting antibody-drug conjugate (ADC) and potent anti-tumor activity in preclinical endometrial cancer patient-derived xenograft (PDX) models. Sutro Biopharma, Inc., is a clinical-stage company relentlessly focused

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February 29, 2024

COVID-19 and Recession: How Big will be the Impact?

By Gaurav Chaudhary Coronavirus  2 Comments

In a blog posted a few weeks ago, I talked about the key strategies that the pharma companies can adopt to deal with the impact of COVID-19 and Recession. The strategies were dependent on the position of the companies on the recession readiness evaluation framework (added below). Check out the blog for more details on

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February 29, 2024

Cell Therapy Pipeline Update: Talaris Therapeutics Announces Initiation of Phase 3 Clinical Trial

By Gaurav Chaudhary Cell Therapy  0 Comments

Cell Therapy pipeline update, Talaris Therapeutics, a late-clinical stage biotechnology company based in Boston, MA and Louisville, KY, announced the initiation of FREEDOM-1 (NCT03995901), the company’s Phase 3 clinical trial of FCR001 in living donor kidney transplant (LDKT) recipients. What is the objective of the trial: This pivotal trial will evaluate the safety and efficacy of a

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February 28, 2024

CARsgen anti-BCMA CAR T CellTherapy Receives RMAT Designation

By Gaurav Chaudhary Cell Therapy  0 Comments

On 28 October 2019, CARsgen Therapeutics, a clinical-stage biopharma company, announced that the FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation to its investigational CT053 CAR-T cell therapy. What is CT-053: CT053 is a fully human anti-BCMA (B Cell Maturation Antigen) autologous chimeric antigen receptor (CAR) T Cell therapy for the treatment of relapsed and/or refractory multiple

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February 28, 2024

COVID-19 and Recession: Identifying Long-Term Growth Opportunities

By Gaurav Chaudhary Biopharmaceutical, COVID-19  0 Comments

Well before the COVID-19 and Recession pandemic, there were warning signs of an imminent US recession. The ongoing pandemic, and trade conflicts between the US. and China, and the US and Europe have just accelerated the fall of the global economy. In fact, as per the United Nations, the world economy is expected to go

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February 28, 2024

Genome Editing Market Update: Intellia Therapeutics Presents Data at the 2019 Annual Congress of the European Society of Gene and Cell Therapy

By Gaurav Chaudhary Therapeutics  1 Comment

Intellia Therapeutics, one of the leading genome editing company focused on the development of curative therapeutics using CRISPR/Cas9 technology is presenting one oral presentation and four poster presentations at the 27th Annual Congress of the European Society of Gene and Cell Therapy (ESGCT) meeting taking place October 22-25, 2019, in Barcelona, Spain. The global genome

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February 28, 2024

Unlocking the Potential of Digital Twins in Healthcare: Benefits, Challenges and Opportunities

By Gaurav Raj Digital Therapeutics  0 Comments

The application of digital twins in healthcare has the potential to revolutionize patient care, improve clinical outcomes, and reduce costs. Digital twins, or virtual replicas of physical objects and environments, are being used in many different industries, and healthcare is no exception. In healthcare, these can be used to provide better patient monitoring, improve remote

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February 27, 2024

Adeno-Associated Viral Vectors: Unlocking the Future Opportunities

By Pomila Kaushal Delivery Systems, Gene Therapy, Vector Manufacturing  0 Comments

Given the potential of gene therapies in targeting the underlying cause of a disease at cellular level,  the gene therapy market has increased considerably over the past few years. Currently, more than 285 gene therapies are being evaluated in different phases of clinical development. Further, various gene therapy developers have raised more than USD 10 billion capital

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February 27, 2024

NFC Tags and RFID Smart Labels for Pharmaceutical and Healthcare Industry: Lets trace medicines from its origin

By Simriti Gupta Anti-Counterfeiting  0 Comments

Traditionally, text and images were printed on pharmaceutical products to convey important information. In recent years, the use of smart labels allows the developer to convey a greater amount of information about the product to the consumers, without the need for additional packaging space. It is worth noting that smart labels contain a transponder code

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February 27, 2024

Gene Therapy Pipeline Update: AGTC Presents Promising Data of its AAV Vectors for Ocular Gene Therapy

By Gaurav Chaudhary Cell Therapy, Gene Therapy  1 Comment

Applied Genetic Technologies Corporation (AGTC), a clinical-stage biotechnology company, developing transformational genetic therapies for patients suffering from rare and debilitating diseases, announced new data from non-clinical studies evaluating the effect of pre-existing anti-AAV antibodies on the transduction and expression efficiency of AAV vectors. Presently, over 250 companies are engaged in the gene therapy pipeline, the gene

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February 27, 2024

Prescription Digital Therapeutics: Advancing Access to the Digital Pills

By Sourindra_Laha Digital Therapeutics, Women’s Digital Health  0 Comments

As per United Nation’s report, the current global population stands at around 8 billion and expected to reach 9 billion by the end of 2030. This increase in population is accompanied with a rise in the incidence of several chronic disease indications. In fact, as per a report published by National Association of Chronic Disease

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February 27, 2024

Bioconjugation of Molecules: A Novel Advancement in Therapeutics

By Prachi Bhalla Canjugation, Conjugation and Labeling of Molecules  0 Comments

Bioconjugation is the process of formation of a single, stable hybrid, wherein one of the entities is a molecule, such as protein, antibody, peptide and small molecule. These molecules can be conjugated with various modalities, such as haptens, enzymes, isotopes, fluorescent tags, carrier proteins, polymers, particle conjugates and photoreactive molecules. Bioconjugation is a subset of

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February 27, 2024

Antibody Drug Conjugates Market Update: Ambrx and NovoCodex Collaborate

By Gaurav Chaudhary Antibody Drug  0 Comments

Ambrx and NovoCodex Biopharmaceuticals announced that they have formed a second collaboration to develop and commercialize Ambrx’s internally developed site-specific antibody drug conjugates. The antibody drug conjugates market is expected to grow at a CAGR of ~10% during the forecast period. What is the focus of the agreement: Under the agreement, Ambrx and NovoCodex will

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February 27, 2024

ADCs Pipeline Update: Avacta Partners with ADC Therapeutics

By Gaurav Chaudhary ADCs Pipeline  0 Comments

ADCs Pipeline

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February 27, 2024

Cybersecurity in Healthcare: A Must Have in Today’s Digital World

By Arun Gupta Cybersecurity, Future Perspectives, Healthcare  1 Comment

The healthcare industry has been amongst the prime targets for hackers over the last several years. In 2017, the healthcare industry had been compromised a number of times, representing 25% of the total number of breaches worldwide. Across these instances, around 31 million records were compromised, stolen or lost. In order to overcome these challenges,

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February 27, 2024

Viral Vector Manufacturing: Current Landscape and Opportunities

By Arun Gupta Biologics, Gene Therapy, Immunotherapy  0 Comments

Over the last few decades, various viral vector manufacturing have been developed, optimized and standardized for introduction of therapeutic DNA / gene of interest into a patient’s body / cells. Currently, the most popular viral vectors, on the basis of their use in active clinical trials, are those based on AAV, adenovirus, lentivirus and retrovirus.

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February 27, 2024

Subcutaneous Medications and Drug Delivery Systems

By Arun Gupta Biologics, Drug Delivery  0 Comments

Biologics constitute a majority of the top selling drugs and represent one of the fastest growing segments of the overall pharmaceutical industry. In fact, the share of biologics in the overall pharmaceutical contract manufacturing market has increased from 16% in 2006 to over 25% in 2017.  Having reported over 70% increase in revenues over the

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February 27, 2024

Trends in Human Health Management: A Journey through Time

By Arun Gupta Healthcare  0 Comments

According to classical Greek mythology, human health management were initially a race of children free from all forms of maladies and sorrow. In order to punish them for some error, the gods sent a girl, named Pandora, with a sealed box that she was forbidden to open. Curiosity caused Pandora to open the box, setting

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February 27, 2024

Myeloid Cell Targeting Therapies: Budding Therapy Against Cancer

By Shivangi Anand Anti-cancer, Anti-cancer Therapy, cancer therapeutics, CELL TARGETING  0 Comments

The global cancer burden is increasing rapidly with over 19 million new cancer cases and 10 million deaths reported in the year 2020. Given the rising prevalence, researchers have made significant efforts in discovering new approaches for the treatment of oncological diseases using cell and gene therapy solutions. With several programs having entered the clinical

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February 27, 2024

New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030

By Arun Gupta Future Perspectives, Oncology  0 Comments

Cancer Therapies continues to be one of the most active segments within the pharmaceutical industry. However, certain biological targets have long eluded drug development efforts. One such target is Ras family, which has been identified to play a critical role in oncogenesis. Scientific literature suggests that the RAS gene is mutated across about 30% of

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February 23, 2024

Outsourcing Antibody Discovery Process: The Profit-Driven Approach to Research

By Gaurav Raj Antibody Discovery  0 Comments

Imagine a world where scientists work together to create special “soldiers” in our bodies called antibodies. These heroes help to fight diseases. Sometimes, scientists ask for help from experts who are really good at finding and designing these antibodies. These experts are like the superhero squad for medical research. They provide their antibody discovery services

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February 22, 2024

Advanced Wound Care Products: The Novel Wound Care and Management Products

By Sourindra_Laha Healthcare  0 Comments

The rising prevalence of chronic diseases has resulted in rise in the associated co-morbidities, including wounds, mental health disorders, vascular disorders, sensory impairments, and others. Among these, the management of wounds has emerged as a critical aspect within the healthcare sector. Presently, more than 15 million individuals worldwide are suffering from various types of wounds,

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February 21, 2024

Industrial and Medical Exoskeleton: Current Landscape and Future Market Outlook

By Jasparam Kaur Medical Devices and Technology  0 Comments

Originally used in biology, the term exoskeleton refers to a chitinous or calcified external skeleton used by various animal taxa for structural support and defense against predators. Drawing from a similar concept, in the field of robotics, exoskeletons are wearable electromechanical devices that have been developed as augmentative devices to enhance the physical performance of

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February 20, 2024

Sleep Apnea Devices Market: Current Landscape and Upcoming Trends

By Ajay Kumar Medical Device  0 Comments

Sleep apnea is an underrecognized sleep disorder, affecting millions of people worldwide. It is characterized by frequent interruptions in breathing during sleep. It happens when the pharyngeal airway (upper airway) gets collapsed or it does not receive signal from the brain, causing a brief pause in breathing. This breathing halt might continue from a few

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February 1, 2024

Cold Chain Packaging – Current Scenario and Future Potential

By Dhriti Gulati Pharmaceutical Packaging  0 Comments

Cold chain is a three-fold concept, involving certain aspects that can be co-related to science, technology, and process development. In terms of science, cold chain industry requires the understanding of chemical and biological processes associated with the product. This technology usually relies on physical methods to ensure desirable temperature conditions for perishable products throughout the

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January 30, 2024

Aesthetic Alchemy: “Artistry of Medical Aesthetic Procedures”

By Nishta Garg Medical Aesthetics  0 Comments

Medical Aesthetics is an area of modern medicine that specializes in improving the outer appearance of an individual without surgery. Medical aesthetic procedures can be broadly categorized into two categories, namely non-invasive and invasive. Medical aesthetic treatments that don’t require to puncture the skin and involve non-surgical devices are termed as non-invasive procedures whereas treatments

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January 29, 2024

Revolutionizing Medicine and Public Health: The Emergence of Big Data in Healthcare

By Jayita Sood Healthcare  0 Comments

Big Data in healthcare refers to the vast amount of data that is continuously expanding and cannot be efficiently stored or processed using traditional tools. Not only in healthcare, but various industries have also adopted big data to enhance their capabilities, improve customer experiences, and strengthen their brand reputation, thereby contributing to overall growth of

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January 26, 2024

Discovering Relief: Exploring Sleep Apnea Medical Devices and Drug Therapies for Sleep Apnea Treatment

By Ajay Kumar Medical Device  0 Comments

Sleep apnea (also known as sleep apnoea), is a sleep disorder characterized by interruptions in breathing during sleep. These interruptions in sleep, often caused by obstruction or reduced airflow, can result in reduced oxygen flow and last up to several minutes. Sleep apnea is often an underdiagnosed condition that can affect all age groups. According

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January 25, 2024

Beyond Batch: The Transformative Force of Continuous Manufacturing

By Pemba Lahmo Continuous Manufacturing  0 Comments

Continuous manufacturing process involves the production of pharmaceutical drug substance in a single run, while operating 24×7. In this process, the drug is developed from its base ingredients / raw materials and processed to the final product in one facility, without any hold time. For decades, pharmaceutical companies have manufactured drugs using batch processing in

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January 24, 2024

Outsourcing Peptide Synthesis: Preferred Choice of Drug Developers

By Mahek Saini Peptide Synthesis  0 Comments

The peptide therapeutics market has undergone substantial evolution since the inception of insulin. It is worth mentioning that over the span of years, the pharmaceutical companies have shifted their focus from conventional interventions towards more advanced pharmacological strategies, such as peptide therapeutics. Presently, over 80 peptide-based drugs are available in the market for myriad of

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January 23, 2024

Oncology Precision Medicine: A Symphony of Hope for Cancer Patients

By Shreeya Agrawal Oncology  0 Comments

Cancer has been recognized as one of the life-threatening diseases, accounting for an alarming global prevalence rate of approximately 20 million new cases and 10 million fatalities. According to the World Health Organization, the global burden for cancer is likely to witness a 60% increase by the end of 2040. Currently, several conventional approaches, such

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January 22, 2024

Exploring the Miracle Antibody Drug Conjugate Technologies

By Ankita Kashyap Antibody Drug  0 Comments

With fourteen approved drugs and several drug candidates being evaluated under different stages of development, antibody drug conjugates (ADCs) are now recognized as a potent class of targeted therapeutics. The success of this relatively novel class of therapeutics is attributed to the ability of lead molecules to specifically identify and eliminate disease associated cells /

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January 19, 2024

BridgeBio Pharma Secures $1.25 Billion to Propel Genetic Medicine Development

By Pemba Lahmo Biopharmaceutical  0 Comments

Introduction In a strategic move to accelerate the development and launch of genetic medicines, BridgeBio Pharma has successfully secured up to USD 1.25 billion from Blue Owl Capital and Canada Pension Plan Investment Board. The cornerstone of BridgeBio’s funding initiative involves a strategic agreement with Blue Owl Capital and Canada Pension Plan Investment Board. In

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January 19, 2024

Chromatography Consumables and Chromatography Instrumentation Industry: Current Scenario and Future Trends

By Ajay Kumar Chromatography  0 Comments

Chromatography finds several applications across different industries, including pharmaceutical, biotechnology, chemical, environmental, food, petrochemical, and other such industries. Specifically in pharmaceutical industry, recent years have witnessed a surge in the demand for chromatography systems / chromatography instrumentation (such as liquid chromatography system, gas chromatography system, gel permeation chromatography, supercritical fluid chromatography) and chromatography consumables (such

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January 18, 2024

Plasma Fractionation: An Indispensable Component for Plasma-derived Therapies Manufacturing

By Ankita Kashyap Plasma fractionation  0 Comments

Plasma fractionation, a critical process in the field of medical science, involves the separation of various components present in blood plasma to create valuable therapeutic products. This intricate procedure has gained significant recognition due to its ability to provide essential treatments and to address various medical indications. The success of plasma fractionation companies hinges upon

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January 18, 2024

Eli Lilly’s Weight-Loss Drug, Mounjaro, Sparks an Epic Run in Pharma Shares

By Pemba Lahmo DRUG DEVELOPMENT  0 Comments

Introduction Over years, Eli Lilly has undergone a significant transformation, positioning itself as the world’s most valuable drugmaker. Renowned for psychiatric drugs such as Prozac, the company faced several challenges in revenue generation during the 2010s due to patent expiration of its innovative drugs. However, a strategic shift and a focus on innovative treatments have

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January 17, 2024

Prefilled Syringes: Delivering Convenience and Precision in Every Dose

By Simran Kaur Drug Delivery  0 Comments

Prefilled syringes are syringes that come pre-filled with a specific dose of medication. They offer several advantages over traditional drug delivery systems (such as vials and syringes), including reduced chances of dosing errors, increased patient compliance and decreased risk of microbial contamination. It is worth highlighting that, prefilled syringes are preferably being used in the

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January 16, 2024

Novartis Steps Back from Cytokinetics Acquisition Amid Stock Plunge

By Pemba Lahmo DRUG DEVELOPMENT  0 Comments

Introduction In a surprising turn of events, Swiss pharmaceutical giant Novartis has decided to step back from the pursuit of much-anticipated acquisition of Cytokinetics, a US based cardiovascular drug developer. This sudden decision has sent ripples through the market, prompting a significant drop in Cytokinetics’ stock value and leaving investors and industry analysts questioning the

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January 16, 2024

Biologics Contract Manufacturing – Current Interest of the Pharmaceutical Industry

By Jasmeet Bhalla Biologics  0 Comments

Biologics represent one of the fastest growing segments of the pharmaceutical industry. This canbe attributed to the rapid pace of innovation in this field, driven by the need for effective and personalized pharmacological interventions. Although biopharmaceuticals offer significant profit margins and have demonstrated the potential to treat a myriad of disease indications, they are generally

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January 15, 2024

Biologics – The Next Step in Revolutionary Medication

By Jasmeet Bhalla Biologics  0 Comments

With the increased interest and gradual shift of investment from small molecule drugs to biologics and the establishment of several biologics manufacturing companies / biologics CMOs, more than 250 biologic therapies and vaccines have been developed, globally. Notably, biologics have higher success rates than conventional small-molecule drugs owing to lesser off-target toxicity of biologics, which

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January 4, 2024

Medical Aesthetics: “Redefining Beauty through Medical Expertise”

By Nishta Garg Medical Aesthetics  0 Comments

In the pursuit of self-reinvention and confidence, medical aesthetics emerges as a powerful tool for reshaping not only the outer appearance of individuals but also their lives as well. Medical aesthetics is a growing area of modern medicine that focuses on improving the cosmetic appearance of an individual through various medical treatments. The idea of

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January 3, 2024

The Promising Potential of Pulsed Field Ablation for Cardiac Rhythm Management

By Jasparam Kaur Pulsed Field Ablation  0 Comments

Heart disorders, which affect millions of lives worldwide, encompass a wide range of abnormalities related to the heart’s structure and function.  Amongst the various types of heart disorders, the prevalence of cardiac arrythmias has grown considerably. This condition manifests as heart beating too fast (tachycardia), too slow (bradycardia) or irregularly. These irregularities in the heart’s

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January 2, 2024

A Deep Dive into Fine Grained Sentiment Analysis of Patient Engagement Solutions

By Ronit Sharma Patient Engagement Solutions  0 Comments

Patient engagement refers to a strategic collaboration between patients and their treatment providers to offer all the relevant resources to patients in order to enable them to make appropriate decisions for their health. This approach allows patients to become well informed regarding the available treatment options, recovery, prescription choices or any other important medical solutions,

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January 1, 2024

The Non Invasive Frontier: Liquid Biopsy Companies Refining Healthcare

By Tamanna Sharma Liquid Biopsy, Liquid Biopsy Market  0 Comments

Cancer has high mortality rate, primarily because of the delayed detection and complexities of current diagnostic procedures. The mortality rates associated with cancer can be significantly reduced if the efforts shift towards the development of methods for early detection of cancer. Amid the increasing burden of cancer and the limitations of traditional tissue biopsies, there

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December 29, 2023

Virtual Clinical Trial Companies: Bringing Revolution in Medical Research

By Shreeya Agrawal decentralized clinical trials companies, Virtual Clinical Trial  0 Comments

Clinical trials are prospective biomedical research studies designed to evaluate medical, surgical or behavioral interventions in people and investigate novel approaches for the diagnosis and prevention / treatment of diseases. In order to gain marketing approval from regulatory authorities for a novel therapeutic intervention, highly accurate and elaborate clinical trial data is required to validate

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December 18, 2023

GalNAc Conjugates – Spearheading the Innovation for Conjugated Drugs

By Sourindra_Laha Next Generation Drug Conjugates  0 Comments

The next generation drug conjugate is relatively a new concept. This novel modality emerged when pharmaceutical developers used non-antibody-based entities as targeting ligand to develop targeted therapeutics. Similar to the structure of the antibody drug conjugates, these next generation drug conjugates use a non-antibody-based targeting ligand, a cytotoxic payload and a linker. However, the key

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December 15, 2023

Chromatography Instrumentation and Chromatography Consumables: The Growing Role in Pharmaceutical Industry

By Ajay Kumar Chromatography  0 Comments

Chromatography is an analytical technique, used for separation, identification and purification of the mixture of components. Chromatography Consumables and Chromatography Instrumentation are used in various industries, including pharmaceutical, biotechnology, chemical, environmental, food, and petrochemical industries, for multiple applications. Specifically in pharmaceutical industry, the demand for chromatography instrumentation and chromatography consumables (such as chromatography resin, packed

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December 14, 2023

Healthcare Through Plasma Fractionation

By Ankita Kashyap Plasma fractionation  0 Comments

Blood plasma, an invaluable component of human blood, stands as a cornerstone in the realm of modern healthcare and therapeutic interventions. In the plasma fractionation industry, plasma donation (which acts as the starting point for plasma fractionation), meticulous screening protocols, and judicious plasma fractionation processes are collectively utilized to develop life-saving plasma-derived therapies. These possibilities

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December 13, 2023

ADC Conjugation – An Innovative Approach for Optimizing Targeted Delivery

By Ankita Kashyap ADC Conjugation  0 Comments

Over the years, researchers and scientists have been on the lookout to find effective ways to treat various types of oncological disorders. This is because one of the approaches, such as chemotherapy, results in killing of both healthy and cancerous cells. Therefore, an innovative approach that can kill the targeted cell while minimizing toxicity was

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December 10, 2023

Magnetic CPAP Masks: A Growing Concern for Patient Safety

By Pemba Lahmo Magnetic CPAP Masks  0 Comments

ResMed has sold millions of magnetic CPAP masks since 2014 and received only five reports of serious harm related to the magnets, which were reported to authorities. Introduction to Magnetic CPAP Masks The medical devices domain is facing a wave of safety concerns as ResMed, a prominent manufacturer of continuous positive airway pressure (CPAP) machines,

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December 10, 2023

Aya Healthcare’s Strategic Acquisition of Winnow AI: A Game-Changer in Healthcare Recruitment

By Pemba Lahmo Healthcare  0 Comments

Aya Healthcare strengthens its physician recruitment technology by acquiring Winnow AI, a move aimed at boosting its capabilities in the digital staffing sector. In a significant move poised to revolutionize healthcare recruitment, Aya Healthcare, a leading healthcare staffing and workforce solutions provider, has successfully acquired Winnow AI. The acquisition marks a strategic partnership between Aya

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December 10, 2023

Novo Nordisk’s Pioneering Endeavor: Unraveling the Complexities of Obesity to Forge a Preventive Pathway

By Pemba Lahmo Healthcare  0 Comments

Novo Nordisk aims to employ insights from obesity drug research to proactively hinder the occurrence of weight gain. Introduction Novo Nordisk, the eminent Danish pharmaceutical giant, has embarked on a groundbreaking journey. While the demand for Novo Nordisk’s weight-loss and diabetes drugs has already propelled the company to the status of Europe’s largest, it now

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December 10, 2023

Unveiling the Future: A Breakthrough Blood Test for Early Alzheimer’s Detection

By Pemba Lahmo Alzheimer's Disease  0 Comments

Introduction In the ever-evolving landscape of medical advancements, a groundbreaking study conducted by Resonant, a Utah-based biotech company specializing in diagnostic tests for neurodegenerative diseases, is developing an Alzheimer’s blood test, a potential game-changer in the early detection of Alzheimer’s disease. The research suggests that a simple blood test could be the key to identifying

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December 10, 2023

Unraveling the Mystery: A Comprehensive Guide to the Science, Safety, and Secrets of Keto Gummies and Weight Loss Gummies

By Pemba Lahmo Healthcare  0 Comments

Introduction In the ever-evolving landscape of weight loss solutions, keto gummies and weight loss gummies have emerged as tantalizing options, promising to revolutionize the journey to a healthier, slimmer self. As the hype around these supplements continues to build, the pressing questions on everyone’s minds are: Do they really work, and are they safe? In

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November 28, 2023

Novo Nordisk Invested EUR 2.1 Billion in a French Manufacturing Site to Meet Growing Demand for Diabetes and Obesity Therapies

By Arun Gupta Metabolomics  0 Comments

In a strategic move to address the escalating demand for its diabetes and obesity therapies, Novo Nordisk, a global healthcare company, has announced a significant investment of EUR 2.1 billion (USD 2.3 billion) in expanding its manufacturing facility in Chartres, France. This capital infusion aligns with Novo Nordisk’s commitment to increasing production capacity for key

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November 12, 2023

Autism and Maternal Immune Activation: Groundbreaking Insights

By Arun Gupta Neurodegeneration  0 Comments

Inflammation induced during pregnancy, a known factor contributing to autism in both mice and humans, plays a pivotal role in altering brain development and, surprisingly, prevents the usual loss of memories formed during infancy

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November 12, 2023

EzriCare Eye Drops Recall: Unveiling a Nationwide Health Crisis

By Arun Gupta Ophthalmic Drugs, Ophthalmic Lenses  0 Comments

The Centers for Disease Control and Prevention (CDC) recently issued a formal health advisory in response to an unprecedented outbreak of carbapenem-resistant Pseudomonas aeruginosa (CRPA), a bacterium notorious for its resistance to specific antibiotics, thereby instigating severe infections in affected individuals. This concerning development has been traced back to the utilization of EzriCare Artificial Tears

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November 7, 2023

The future of RNA-based Therapeutics  and Vaccines: Introducing advanced, Unrivalled Treatment Approaches

By Dhriti Gulati RNA Therapeutics  0 Comments

RNA-based therapeutics have completely revolutionized the healthcare segment, greatly influencing the study and treatment of human diseases by conferring precise targeting ability to therapeutic modalities. Further, the enhanced safety and efficacy of treatment using RNA-based therapeutics has surpassed the safety profiles of the conventional treatment approaches. Considering their vast potential, stakeholders are actively engaged in

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November 6, 2023

Unveiling the Future of Liquid Biopsy Market

By Tamanna Sharma Liquid Biopsy, Uncategorized  0 Comments

Cancer is the second leading cause of death globally, and the increasing global incidence of cancer is becoming a critical health challenge. According to WHO, approximately 16.3 million cancer related deaths are likely to occur by 2040. In order to address the growing cancer burden, numerous cancer research organizations are actively adopting innovative strategies and

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November 3, 2023

Prominent Reasons Behind The Failure Of NAMPT inhibitors And Key Strategies Adopted By Developers To Overcome Such Challenges

By Ronit Sharma NAMPT inhibitors  0 Comments

NAMPT inhibitors are a class of drugs that target the enzyme nicotinamide phosphoribosyltransferase (NAMPT). This enzyme plays a crucial role in the production of nicotinamide adenine dinucleotide (NAD+), a molecule that is essential for cellular metabolism. NAMPT inhibitors work by blocking the activity of NAMPT, which in turn reduces the production of NAD+. NAD+ is

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November 2, 2023

Agricultural Biologicals Market: Current Landscape, Growth Opportunities and Future Market Outlook

By Kumar Shagnick Agriculture Biologics  0 Comments

The agricultural biologicals market (including biopesticides market, biofertilizers market and biostimulants market) has emerged to be an essential component of sustainable farming practices in order to grow organic food products. These novel bio solutions have the potential to address a number of challenges associated with conventional farming. Presently, over 185 nations worldwide have started adopting

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November 1, 2023

Digital Therapeutics: Pioneer of the Modern Healthcare System

By Ronit Sharma Digital Therapeutics  0 Comments

The COVID-19 pandemic and its reverberation led to a paradigm shift in the healthcare industry. It acted as a catalyst of change and led to rapid transformation of the healthcare system and the industry. One among the many healthcare transformation evolved out of it is the transformation of the general healthcare services to the remote

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October 31, 2023

Next Generation RNA Therapeutics and Vaccines – A Marvel of The Lifesciences Industry

By Dhriti Gulati Next Generation RNA Therapeutics, RNA Therapeutics  0 Comments

In the past few years, Next Generation RNA therapeutics have emerged as one of the key therapeutic modalities in the modern healthcare industry. These RNA based therapeutics play a crucial role in protein production and regulation of gene functions. In addition, they offer enhanced therapeutic and safety profiles as compared to traditional treatment approaches. However,

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October 30, 2023

Decentralized Clinical Trials: The Future of Clinical Research

By Shreeya Agrawal Clinical Trials, Decentralized Clinical Trials, virtual clinical trials  0 Comments

Over the past decade, the rise of this digital technology has transformed various sectors, from finance to healthcare. One particular area that has seen significant innovation is the realm of clinical trials. Traditionally conducted at centralized sites like hospitals or clinics, the latest trend is moving towards decentralized clinical trials (DCTs). Clinical trials are prospective

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October 28, 2023

Injected Version of Eisai/Biogen Alzheimer’s Drug Works as Well as IV Leqembi

By Arun Gupta Alzheimer's Disease, Alzheimer's Pipeline, Alzheimer’s Disease  0 Comments

On 26 October 2023, Eisai and Biogen’s Alzheimer’s drug, Leqembi, was found to be as effective as the current intravenous administration in removing toxic brain plaques. However, the review conducted by the drugmakers revealed that the rates of serious side effects were higher when using the drug in its subcutaneous injection form. The company’s analysis

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October 27, 2023

BioNtech Reports Preliminary Phase I/II Results of its CAR T Cell Therapy CarVAC and BNT211-01 (NEO-PTC-01) at European Society for Medical Oncology (ESMO) Conference

By Arun Gupta cell and gene therapy, Cell Therapy  0 Comments

On 24 October 2023, BioNtech announced the preliminary results of phase I/II trial evaluating BNT.221-01, a combination of Claudin 6 (CLDN6)-targeted CAR T cell therapy and the mRNA-based CAR T booster CarVac at ESMO conference in Madrid. BioNtech reported acceptable safety and tolerability data and first hints to efficacy in solid tumours. The CAR T

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October 26, 2023

Merck Enters into a Development Agreement with Daiichi for Antibody Drug Conjugates

By Arun Gupta ADC Conjugation, Antibody Drug, Next Generation Drug Conjugates  0 Comments

On 23 October 2023, Merck announced a development agreement for Daiichi Sankyo’s clinical-phase antibody-drug conjugate, namely patritumab deruxtecan (HER3-DXd), ifinatamab deruxtecan (I-DXd), and raludotatug deruxtecan (R-DXd), targeting cancer. Merck has invested $5.5 billion to jointly develop three of its candidate cancer drugs and is likely to invest up to $22 billion in addition depending on

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October 25, 2023

Single-use Bioreactor: An Indispensable Component for Biopharmaceutical Manufacturing

By Mahek Saini Uncategorized  0 Comments

The limitations of stainless-steel bioreactors such as high risk of contamination, process related challenges and high operational cost have prompted innovators to develop more advanced single use bioreactor in order to meet the rising demand for safe and efficacious biotherapeutics. Conventional stainless-steel bioreactors require more energy as compared to the single use bioreactor for sterilization,

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October 24, 2023

HPAPIs – Current Interest of the Pharmaceutical Industry

By Simran Kaur Cytotoxic Drugs and HPAPI Manufacturing, HPAPI Manufacturing  0 Comments

Owing to the advancement in clinical pharmacology and oncology domain, and the rising demand for targeted therapeutics and precision medicines, high potency active pharmaceutical ingredients (HPAPIs) and cytotoxic drugs have become one of the key areas of interest to researchers and drug manufacturers across the globe. HPAPIs, due to their selective mode of action, are

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October 23, 2023

RNA Therapeutics: A Novel Approach to Treating Diseases

By Ronit Sharma RNA Therapeutics  0 Comments

RNA therapeutics are a novel class of biopharmaceuticals that harness the power of RNA molecules for the treatment and prevention of a wide range of disorders, including oncological, and genetic disorders as well as infectious diseases. These therapeutics are broadly classified into two categories, namely coding RNAs and non-coding RNAs. Coding RNAs include messenger RNA

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October 20, 2023

Bacteriophage Therapy – A Revolutionary Approach Towards Multi-Resistant Bacteria

By Ankita Kashyap Bacteriophage  0 Comments

Bacteria plays a crucial role in maintaining the ecosystem balance. However, there are few species of bacteria that can cause several infectious diseases (such as strep throat, salmonellosis, tuberculosis, whooping cough). These are mainly transmitted through air, water, living organisms, and food. Further, the spread of infections to a larger population is attributed to the

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October 17, 2023

Rising Demand for DNA and Gene Cloning Service Providers

By Shreeya Agrawal DNA Cloning Market  0 Comments

DNA cloning refers to the process of generating multiple copies of a particular DNA segment. DNA and Gene Cloning involves the isolation of a DNA sequence of any species and its insertion into a vector to enable growth without any alteration in the original DNA sequence. Once isolated, molecular clones can be used to generate

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October 16, 2023

Biopharmaceutical Filtration: A Deep Dive

By Ankita Kashyap Biopharmaceutical Filtration  0 Comments

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. It involves the separation of unwanted particles from biological materials to obtain contaminant free products. Filtration plays a crucial role in ensuring the safety, efficacy, and quality of biopharmaceutical products. The biopharmaceutical industry uses different filtration systems depending on

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October 13, 2023

Can The Next Generation Drug Conjugates Revolutionize The Rare Disorder Domain?

By Simriti Gupta Next Generation Drug Conjugates  1 Comment

Over the last two decades the pharmaceutical industry has observed a paradigm shift from conventional drug delivery strategies to more enhanced, potent, and targeted therapeutics. This led the researchers to find alternative pathways and drug delivery strategies to enhance the potent delivery of the drug to the site of action. As a result, in late

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October 12, 2023

Berkus Method of Start-up Valuation to Evaluate Start-ups Engaged in Digital Twins Domain

By Gaurav Raj Digital Therapeutics  0 Comments

Digital twins is a rapidly emerging space and there are several start-ups working to provide novel solutions. In this article, we’ve looked at a method of company valuation. Berkus start-up valuation is a method developed by the American venture capitalist and angel investor, Dave Berkus in the mid 1990’s. The Berkus method was designed to

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October 11, 2023

Agricultural Biologicals: An Answer to a Sustainable Future

By Kumar Shagnick Agriculture Biologics  0 Comments

The introduction of the Green Revolution in the late 1960s led to a substantial agricultural intensification. The primary objective of the initiative was to feed a growing population with limited land resources and enhanced crop yields. Consequently, the use of agrochemicals, such as chemical pesticides and fertilizers, became an integral part of this industrialized approach.

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October 5, 2023

Pharmaceutical Polymers / Medical Polymers -Current Scenario and Future Potential

By Simran Kaur Pharmaceutical Polymers  0 Comments

Driven by the increasing need for safe and efficient medical devices and drug delivery systems, the pharmaceutical polymers / medical grade polymers domain is advancing significantly. There has been a rise in the development of polymers for biopharma with improved biocompatibility, biodegradability and functionality. It is worth highlighting that the manufacturing of polymers for biopharma

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October 4, 2023

Future of Bispecific Antibody: Exploring the Rise in Approvals

By Gaurav Raj Antibodies  0 Comments

Bispecific antibodies are a type of antibody that can bind to two different targets at the same time. They are designed to recognize and bind to two specific molecules, such as a tumor cell and an immune cell, or two different parts of the same molecule. This allows them to potentially be more effective in

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October 3, 2023

Bioreactor Industry: Current Scenario and Future Trends

By Jasparam Kaur Bioreactors  0 Comments

Bioreactors and fermenters are complex systems used across numerous sectors of the industry, for the production of pharmaceuticals, nutraceuticals, food, and beverages. These systems provide controlled conditions for cell growth by providing optimum nutrient supply, and oxygenation, enabling the production of biologics. Bioreactors and fermenters can range from small laboratory-scale to industrial-scale systems, and may

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October 2, 2023

Nanoparticle Formulation: A Paradigm Shift towards Novel Drug Delivery

By Prachi Bhalla Nanoparticles  0 Comments

Nanoparticles (zero-dimensional nanomaterials) are ultra-fine particles with overall dimension ranging between 1-100 nm. Owing to their unique size and physicochemical properties (surface roughness, surface area, surface energy, crystal structure and shape), nanoparticles can be widely used as a contrasting agent in medical imaging, a vesicle to cross the blood-brain barrier and a carrier for targeted

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September 29, 2023

Cryobags – Current Scenario and Future Trends

By Jasmeet Bhalla Cryopreservation Bags  0 Comments

Since the 1980s, there have been significant advancements in the cryopreservation techniques used for storing stem cells, particularly hematopoietic stem cells and embryonic stem cells, which are essential in various medical applications, including regenerative medicine and biobanking. This can be attributed to the fact that the demand for biologics has been constantly increasing and driven

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September 22, 2023

Wearable Injectors Unveiled: Future of Healthcare

By Rupali Bhardwaj WEARABLE INJECTORS  0 Comments

In the continuous evolving landscape of healthcare, wearable injectors have emerged as transformative devices with the potential to redefine patient care. These innovative instruments combine precision, convenience, and patient-centered design to revolutionize drug delivery. In this detailed blog, we will delve deeply into the world of wearable injectors, exploring their underlying technology, advantages, limitations, diverse

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September 21, 2023

Cannabis Testing: Unlocking the Future Opportunities in Healthcare

By Kumar Shagnick Cannabis  0 Comments

Cannabis belongs to a class of flowering plants famous for its psychoactive properties and recreational uses. Cannabis sativa is the most widely used variety of the plant; other forms such as Cannabis indica and Cannabis ruderalis are also popular in different regions.  In earlier times, cannabis was used primarily for recreational purposes, however, medical applications

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September 20, 2023

Advancements In Automation Of Manufacturing Processes: Key Value Driver For Escalated Interest In The Cell Therapy Domain

By Dhriti Gulati Cell Therapies, Cell Therapy Manufacturing  0 Comments

Cell therapies are based on the premise that the patient’s own cells (autologous), or those from a healthy donor (allogeneic), can be genetically re-programmed to combat various diseases. In this form of therapy, patients are injected with living and intact human cells that are deemed to be capable of providing therapeutic benefit. It is important

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September 19, 2023

Cryogenic Bags – A Critical Component in the Successful Delivery of Biological Samples and Therapies

By Jasmeet Bhalla Cryomacs Freezing Bags, Cryopreservation Bags  0 Comments

Owing to the ability to preserve a wide variety of elements for such a long period of time, including cells, tissues, blood and DNA, cryopreservation has emerged as a key focus area for stakeholders in the biopharmaceutical industry. It is worth mentioning that it is extremely difficult to store biological components, such as stem cells

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September 18, 2023

On Body Injectors: The Future of Drug Delivery

By Rupali Bhardwaj WEARABLE INJECTORS  0 Comments

With the increasing global population, the incidence rates of several chronic disease indications, such as diabetes, heart disorders, neurological disorders and oncological disorders, are on the rise. Therefore, medical technology is rapidly evolving, enabling more advanced and patient-friendly methods of drug delivery. In the pursuit of creating patient-centric healthcare solutions, the medical industry has witnessed

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September 5, 2023

How Can Quantum Computing Technology Help In Pharmaceutical R&D?

By Rupali Bhardwaj Quantum Computing, Quantum Technology  0 Comments

The early stages of research related to drug discovery, including the identification of a relevant biological target and a viable lead compound, play a crucial role in the overall success of a drug candidate in preclinical and clinical studies. It is also worth noting that the process of drug discovery is extremely demanding, both in

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September 4, 2023

Companion Diagnostics Services: Future of Outsourcing

By Jasparam Kaur Companion Diagnostics, Diagnostics  0 Comments

In the recent years, service industry has become a fast-growing segment in the overall healthcare domain – thanks to the steady increase in demand for contract research organizations (CROs) and contract manufacturing organizations. The need to focus on developing more efficient interventions, within stipulated timelines and budget constrains is the key driver for outsourcing operations

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September 1, 2023

Breaking the Waves: How Blue Ocean Strategy in Healthcare Can Propel Pharma / Biotech Companies to Success

By Ronit Sharma Red and Blue Ocean Strategy  0 Comments

In the fiercely competitive landscape of the pharma and biotech industries, standing out from the crowd is crucial for success. One strategy that has gained traction in recent years is the Blue Ocean Strategy. By charting new waters and creating uncontested market spaces, companies can differentiate themselves and unlock unprecedented growth opportunities. In this blog

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September 1, 2023

Molecular Switch: A Novel Platform for Switching Genes On and Off

By Pemba Lahmo Gene Switch, Gene Therapies  0 Comments

The notion that genes might be turned on and off was discovered several decades ago when studies revealed that E. coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Molecular switch is a site on genes where regulatory molecules can bind to trigger transcription process,

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August 31, 2023

Nutrigenomics: The Future of Personalized Nutrition

By Pemba Lahmo Nutrigenomics  0 Comments

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Given the recent shift from the one-size-fits-all model to a more personalized mode of treatment, there has been a growing interest for identification and adoption of novel techniques. According to a study, around 20,000 genes are

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August 31, 2023

Tissue Engineering: The Power of Tissue Regeneration

By Ronit Sharma Tissue Engineering  0 Comments

Do you know that scientists are now able to grow body parts in the lab? Yes, you read it right! This incredible medical breakthrough is called tissue engineering. So, what is tissue engineering? It’s a process that uses a combination of cells and biochemical and physicochemical factors to improve or replace biological functions. In simpler

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August 30, 2023

Digital Manufacturing – Current Scenario and Future Trends

By Jasmeet Bhalla BIOMANUFACTURING  0 Comments

Breakthroughs in the biotechnology industry, over the last few decades, has provided a considerable boost to the overall development landscape of biopharmaceutical drugs. In 2022, a milestone was witnessed when the number of approvals received by biologics narrowly outpaced those reported by small molecules. Further, in the same year, nearly half of the biologic approvals

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August 30, 2023

Biologics Contract Manufacturing: Changing Promise into Reality

By Jasmeet Bhalla Biopharmaceutical, Contract Manufacturing  0 Comments

Over the last few decades, the development landscape of small molecule drugs has been significantly impacted by various biotechnology breakthroughs. Further, with the advent of novel technologies, biologics have made a significant impact in the pharmaceutical domain, delivering ground-breaking treatment for a myriad of disease indications, including immunological, oncological and rare disorders. In this context,

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August 29, 2023

Cell Therapy Consumables Industry: Current Scenario and Future Trends

By Arun Gupta Cell Therapy  0 Comments

Cell therapy is the therapeutic approach which involves the injection of healthy cells in the human body, in order to replace the diseased / non-functioning cells to regulate certain functions. Driven by the benefits offered by cellular therapies and recent approvals by regulatory authorities, the demand for such therapies has increased considerably. This trend has

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August 29, 2023

Cell and Gene Therapy CROs: The Next Growth Opportunity

By Jasmeet Bhalla cell and gene therapy, Cell Therapies, Cell Therapy, Gene Therapies, Gene Therapy  0 Comments

Over the years, cell and gene therapy (CGT) and other advanced therapy medicinal products (ATMPs) have managed to capture the interest of both drug developers and healthcare investors. Their popularity can be attributed to various factors, such as minimal side effects, clinical efficacy and their personalized nature. However, there are several complexities associated with the

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August 24, 2023

Quantum Computing in Drug Discovery: Unleashing the Power

By Rupali Bhardwaj Quantum Computing  0 Comments

Drug discovery has always been a time-consuming process. On an average, it takes 10-15 years and investments worth USD 4-10 billion to commercially launch a drug. In order to address these concerns, developers are shifting their focus from traditional techniques to the use of novel discovery techniques. Quantum computing in drug discovery has emerged to

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August 21, 2023

Novel Spectrometry Platforms: Key Advancements

By Nancy Kapila Future Perspectives, Spectrometry  0 Comments

Spectrometry is an analytical technique that is used to analyze the fundamental components of a radiation or ion beam’s spectrum. There are two main divisions of spectrometry, which involve the use of electromagnetic radiation and ionization (also known as mass spectrometry), respectively. The former division of spectrometry uses electromagnetic radiation from different regions of an

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August 18, 2023

RNA Sequencing Services: Growth Opportunities

By Nancy Kapila Contract Service Providers, mRNA, Next Generation Sequencing, Service Providers, SINGLE CELL SEQUENCING, Uncategorized  0 Comments

Genome sequencing has historically been classified into DNA sequencing and RNA sequencing. DNA sequencing generates data that is very robust, reproducible, insightful, and can be applied to genes having different expression level by selecting genomic region. In spite of several developments made to increase the efficiency of DNA sequencing even further, there are certain challenges

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August 17, 2023

Market Landscape of Blockchain in Healthcare: The growing use of the technology in Drug Discovery and Clinical Trials

By Muskaan Arora Blockchain  0 Comments

In recent years, blockchain has garnered significant interest of researchers, as well as industry players, as it has proven to be a versatile tool for decentralized monetary transactions and data exchange in various industries, such as banking, cyber security, supply chain management, government and healthcare. Several stakeholders in healthcare have adopted blockchain for various operations,

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August 17, 2023

TIL Cell Therapy: Future of Cancer Immunotherapies

By Ajay Kumar Cancer Immunotherapies, Cell Therapies, Cell Therapy, T-Cell Therapies  0 Comments

Cancer is known to be one of the leading causes of deaths worldwide. In fact, as per the WHO, close to 10 million cancer related deaths were reported in 2020. Further, it is estimated that, by the end of 2040, 27.5 million new cancer cases will be added to the global numbers, exerting tremendous physical,

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August 16, 2023

mRNA Manufacturing: Pioneering the Future of Medicine

By Ajay Kumar BIOMANUFACTURING, Continuous Manufacturing, Contract Manufacturing, Manufacturing, mRNA  0 Comments

mRNA manufacturing has completely revolutionized the field of medicine and significantly influenced the study and treatment of human diseases. The success of COVID-19 vaccines paved the path for mRNA vaccines and therapeutics. Safety, efficacy and rapid production of mRNA drives the interest in this domain. However, mRNA production is fraught with several challenges as the

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August 16, 2023

Intracellular Drug Delivery – A Potential Treatment for Lethal Orphan Diseases

By Tanya Shastri Delivery Systems, Drug Delivery  0 Comments

What do we do when we have to revive a drying plant? Of course, we will have to water the roots of the plant regularly to make it back to its freshness. This could be a simple method to revive a drying plant, as directing water at the base of your plant delivers the hydration

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August 15, 2023

Cell Free Protein Expression: Transforming Biomanufacturing

By Divya Nagla BIOMANUFACTURING, Cell Free Systems  0 Comments

Overview of Cell Free Protein Expression Cell free protein expression systems are ­in-vitro platforms which allow occurrence of biochemical reactions in the absence of living cells. These expression systems utilize bio machinery harvested from the lysate of disrupted cells for the manufacturing of a wide array of macromolecular and small molecule products. Biomanufacturing utilizing cell

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August 15, 2023

TCR Therapy: Revolutionizing Cancer Immunotherapy

By Ajay Kumar Cell Therapies, Cell Therapy, T-Cell Therapies, TCR therapies  0 Comments

Cancer is known to be one of the leading causes of deaths worldwide. In fact, as per the WHO, close to 10 million cancer related deaths were reported in 2020. Further, it is estimated that, by the end of 2040, 27.5 million new cancer cases will be added to the global numbers, exerting tremendous physical,

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August 14, 2023

Manufacturing Execution System: A Necessity in Healthcare Market

By Ronit Sharma BIOMANUFACTURING, Continuous Manufacturing, Manufacturing, Manufacturing Execution Systems  0 Comments

Like any other industry, the healthcare industry is drastically growing in its way. Thus, manufacturers need to update themselves with the new technologies and tools to stay relevant and competitive with the current market trends. Manufacturing execution system plays a crucial role in achieving long term competitive advantages in the healthcare industry. Manufacturing execution system

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August 14, 2023

Novel Antibody Therapies: Addressing Unmet Needs for Oncological Disorders

By Nancy Kapila Antibodies, Antibody Discovery, Antibody Therapy  0 Comments

Antibodies are key components of the immune system that bind to specific markers on cells or tissues, thereby offering first line of defense against multiple disorders. The novel antibody therapies include different classes of antibodies, that are responsible for killing or inhibiting disease-causing agents. These therapies target proteins that are expressed on the surface of

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August 10, 2023

MES System: A Step Towards Smart Manufacturing in Healthcare

By Ronit Sharma BIOMANUFACTURING, Continuous Manufacturing, Manufacturing, Manufacturing Execution Systems  0 Comments

The continuously growing demand for healthcare products and present economic environment drives the need for adoption of automated tool and technologies in order to improve manufacturing, process, increase throughput reduce cycle time, maintain quality and to get the best out of the available resources to eliminate unnecessary production costs. It is worth mentioning that in

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August 9, 2023

Novel Antibody Therapies Market: Current Scenario and Future Potential

By Hardik Patel Antibody Discovery, Antibody Drug, Antibody Humanization, Antibody Purification, Antibody Therapy  0 Comments

Novel antibody therapies are chimeric proteins having antibodies attached lethal effector molecules. Currently, six of these therapies are commercially available, while around 140 molecules are under development majorly for oncological disorders. Multiple novel antibody formats have been engineered to enhance therapeutic efficacy. This has opened a new target space for the development of antibody therapeutics

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August 9, 2023

Unlocking the Potential of Liposome Drug Delivery

By Nancy Kapila Liposomes, lipososomes  0 Comments

Introduction to Liposome Owing to their flexible physicochemical and biophysical characteristics, which allow easy manipulation to address various delivery requirements, liposome drug delivery has evolved into an attractive delivery system. Liposome was initially identified and described as swollen phospholipid systems, called Banghasomes, by British hematologist Alec D. Bangham, in 1961 at the Babraham Institute, University

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August 8, 2023

Transformation of Biopharmaceuticals Manufacturing Through Single Use Bioreactors

By Mahek Saini BIOMANUFACTURING, Bioreactors, Contract Manufacturing, Manufacturing, Single-use Bioreactors, Single-use Technology  0 Comments

Recently, in the biopharmaceutical industry an increasing demand for quality biologics has been observed, where single use bioreactors have emerged as one of the most prominent and reliable solution for biomanufacturing. Disposable bioreactors have transformed the process of conventional biomanufacturing, and their adoption is increasing rapidly for production of various biologics, such as antibody, recombinant proteins,

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August 8, 2023

Medical Device Coating and Surface Modification Technologies: Current Market Landscape and Emerging Opportunities

By Kumar Shagnick Medical Device, Medical Device Coatings, Medical Devices and Technology  0 Comments

Over the past 50 years, the medical device industry has seen several notable developments. In fact, the use of biomedical devices, such as medical implants, surgical instruments, and prostheses has increased substantially over the time. Every year, millions of individuals undergo surgeries and implantations. Cardioverter defibrillators, prosthetic hips and knees, contact lenses, and cardiac pacemakers

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August 7, 2023

Cell Free System market: Current Landscape and Future Market

By Divya Nagla Cell Free Systems  0 Comments

In recent years, cell free system / cell free protein expression system have emerged as a promising alternative for the conventional cell-based biomanufacturing process. It is a well-known fact that traditional biomanufacturing is a complex process that requires living cells and specific conditions in order to maintain proper homeostasis for cell growth. Moreover, cell based

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August 1, 2023

Elevating Healthcare: The Soaring Potential of Medical Delivery Drones!

By Tanya Shastri Medical Drone Delivery  0 Comments

Once upon a time, the concept of medical delivery drones seemed like something out of a science fiction movie. Who would have imagined that these remote-controlled flying machines could become a lifeline in the field of healthcare? A Life-Changing Invention In recent times, COVID-19 has sparked significant investments in the medical drone market, leading to

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June 30, 2023

Next Generation Biomanufacturing – The Upcoming Era of Digital Transformation

By Jasmeet Bhalla BIOMANUFACTURING, Continuous Manufacturing, Contract Manufacturing, DNA Manufacturing, Manufacturing, Manufacturing Execution Systems, Microbial Manufacturing, Uncategorized, Vector Manufacturing  0 Comments

Upon realizing the potential of digital biomanufacturing over traditional processes, players are actively undertaking initiatives to adopt advanced platforms to drive operational excellence, visibility, control and synchronization in bioprocessing. Industry 4.0: An amalgamation of physical equipment and smart software Digital biomanufacturing offers real-time process optimization based on factors, such as anticipated product quality and batch

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April 5, 2023

Non Viral Transfection Reagent: Market Landscape and Key Trends

By Ankita Kashyap cell and gene therapy, Gene Technologies, Gene Therapies, Gene Therapy, Viral Diseases  0 Comments

In order to manipulate the cells, genetic material / nucleic acid is artificially introduced into the cells by using specific carriers / vectors. This process is known as transfection. It does not use viral components for transfection and are aimed at circumventing the challenges, such as inflammation, immunogenicity and non-specific transduction, associated with viral vectors.

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April 4, 2023

Deep Learning Technology: Advanced Human Neural Networks

By Dhriti Gulati artificial intelligence, Digital Therapeutics  0 Comments

Artificial intelligence is the ability of a system to think like humans, discover the meaning, and execute the tasks. Recent advancements in the AI in drug discovery market (e.g. deep learning technology, machine learning) have contributed to an invariable increase in the popularity of this technology across several othe industries as well, having impacted the

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March 17, 2023

mRNA Therapeutics Market: Current Scenario and Future Trends

By Jasmeet Bhalla mRNA  0 Comments

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in part of the protein engineering market because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein. In the last few years, researchers have become interested

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March 16, 2023

Flow Cytometer Market Analysis: Current Trends and Future Projections

By Yash Kumar Cell Cytometers  0 Comments

The domain of novel cell cytometers, particularly flow cytometer, has attracted much attention within the global biopharmaceutical industry in recent years. This popularity can be attributed mainly to the need of these tools to address the rising prevalence of chronic disease conditions. Flow cytometers allow simultaneous characterization of cells from a mixed population, thereby helping

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March 15, 2023

Clinical Trial Recruitment – Determinant of Successful Clinical Trials

By Simran Kaur Patient Recruitment  0 Comments

Clinical trials are a fundamental requirement for evaluating the safety and efficacy of novel therapeutic interventions. Initiating a clinical trial is a complex and time-consuming process, involving suitable planning and execution. In addition, there are several other challenges, including inefficiencies related to data handling, and difficulties associated with patient engagement solutions, which further complicates the

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March 14, 2023

AI Pathology: Key Trends and Opportunities

By Ronit Sharma Diagnostics, Digital Therapeutics, Non-Invasive Diagnostics  0 Comments

How is AI being used in Digital Pathology? AI pathology is a transformative technology that has enabled pathologists to make the shift from visual inspection of tissue samples to automated image analysis. With the advent of artficial intelligence pathology, researchers are now benefiting from computerized image analysis software that can draw conclusions and deliver diagnoses

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March 10, 2023

Rare Kidney Disease: Future Miracle Drugs

By Arun Gupta Chronic Kidney Disease  0 Comments

Kidney disorders are one of the most common causes of mortality, accounting for 850 million deaths, per year, across the globe. Over 300 congenital, inherited and acquired disorders fall under the umbrella of rare kidney disease. It is worth mentioning that these set of disorders are known to have a serious effect on the general

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March 8, 2023

Introduction To Exosome Therapeutics

By Aanchal Chaudhary Exosomes, NOVEL DRUG  0 Comments

In  recent years, therapies utilizing extracellular vesicles have garnered significant attention among the industry stakeholders for the treatment of diverse target indication, primarily owing to the various benefits offered by them, including target specificity, enhanced tissue regeneration, and reduced inflammation and chronic pain. Over time, various research studies have demonstrated the potential of exosomes (membrane

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March 3, 2023

Women’s Health Market: The Rising Investment Opportunities

By Diksha Agarwal Digital Therapeutics, Women’s Digital Health  0 Comments

Digital health is a broad term that refers to the utilization of communication and information technologies to manage, track, and improve the overall healthcare delivery system. As a part of the growing digital therapeutics market to optimize patient healthcare and the development of pharmaceuticals, the women’s health market has witnessed significant rise in investments in

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March 2, 2023

Genotoxicity Testing: The Future Safety Assessment Opportunities

By Pomila Kaushal Testing Services  0 Comments

Genotoxicity testing refers to the evaluation of detrimental effects of chemical or physical agents on the genetic processes and related hereditary material of living cells. On the other hand, mutagenicity is the process of inducing irreversible and transmissible alterations in the genetic material of organisms either spontaneously or through mutagenic activity. Disruption of the integrity

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February 28, 2023

Modular Construction – Retrofitting Conventional Buildings

By Nishta Garg MODULAR FACILITIES  0 Comments

Shifting construction away from traditional sites and into factories could dramatically change the way we build. Will off-site builds bolster construction this time around? Over the years, construction has straggled behind other sectors in terms of efficiency. Off-site builds or modular construction is a powerful way to reform construction business saving more time, labor, cost

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February 27, 2023

Long Acting Injectable: Delivering Therapeutic Modalities

By Prachi Bhalla Drug Delivery, Injectors, Injectors Market, Medical Devices and Technology  0 Comments

Over the last two decades, the pharmaceutical industry has observed a paradigm shift from conventional drug delivery strategies to the long acting injectable products to treat several disease indications, such as ophthalmic disorders, oncological disorders, neurological disorders and infectious diseases. Long acting injectable products have emerged as the novel and advanced drug delivery system which

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February 23, 2023

Medical Coatings and Modification Technologies for Medical Devices: The Need and Advantages

By Kumar Shagnick Medical Device, Medical Device Coatings, Medical Devices and Technology  0 Comments

Over the past 50 years, the medical device industry has seen several notable developments. In fact, according to the World Health Organization (WHO), presently, around two million medical devices are available across the globe. Further, since 2020, the Food and Drug Administration (FDA) has approved 125 medical devices. The growing demand for complex medical devices,

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February 17, 2023

Demand for Fill Finish Manufacturing Services for Biologics

By Ridhima Gupta Biologics  0 Comments

Th increasing demand for biologics has led to an increasing need for production capacity, which is characterized by high quality standards. Although, it is a challenging field, outsourcing has emerged as a promising segment, especially for drug fill finish manufacturing and aseptic fill finish operations. Despite being one of the crucial steps of all the

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February 16, 2023

The Future of Dentistry: Dental 3D Printers

By Rohit Pareek 3D Bioprinting, Dental 3D Printing  0 Comments

3D printing, also known as additive manufacturing, is a method of producing 3-dimensional objects layer-by-layer, using a computer aided design. Owing to its ability to print complex models using a wide range of materials, 3D printing has applications across various industries, including dental, aerospace, automotive, healthcare, food, fashion, mechanical engineering and other manufacturing industries.  In

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February 15, 2023

Bioavailability Enhancement Technologies

By Jayita Sood Service Providers  0 Comments

A study conducted on terminated drug development projects revealed that majority of the drug candidates fail in early drug development phases, due to the problems associated with their pharmacokinetic profiles, ADME (distribution, metabolism, absorption and excretion) properties and toxicity-related issues. Moreover, it is a well-established fact that the systemic / local absorption and distribution of

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February 14, 2023

Liposome Manufacturing: Service Providers Landscape

By Diksha Agarwal lipososomes, Service Providers  0 Comments

In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material. Liposomes are small, artificial and lipid-based bilayered spherical vesicles, which are created spontaneously by hydrated phospholipids. Owing to their ability

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February 13, 2023

Understanding mRNA Production: The Key to Modern Medicine

By Ajay Kumar mRNA  0 Comments

Messenger ribonucleic acid (mRNA) is a single-stranded molecule, which carries coding sequence and plays a prominent role in protein synthesis. It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. Despite the challenges associated, there is a growing need for mRNA production service providers.

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February 10, 2023

TIL Therapies: A New Paradigm in Cancer Treatment

By Ajay Kumar Cancer, cancer therapeutics, T-Cell Immunotherapies, T-Cell Therapies  0 Comments

Modified tumor-infiltrating lymphocytes or TIL therapies have emerged as a viable and potent option to selectively eradicate the tumor population, with minimal side effects. Till date, several clinical trials have demonstrated the efficacy and therapeutic superiority (over conventional treatment options) of TIL-based therapies. Their tumor-cell killing efficiency is attributed to the fact that they are

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February 9, 2023

Viral Clearance Testing and Viral Testing Services

By Manoti Vyas Testing Services  1 Comment

Considering the rising demand for biologics, innovators in the biopharmaceutical industry are constantly exploring avenues that would enable them to overcome the existing technical and operational challenges related to viral clearance testing for timely approval of biologics. Outsourcing the viral clearance testing studies has emerged as a promising alternative for most of the manufacturers. Despite

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February 8, 2023

AI Cancer Treatment: Current Scenario And Future Potential

By Muskaan Arora artificial intelligence, Cancer, CANCER MARKET, cancer therapeutics, Novel Cancer, Oncology  0 Comments

In the last decade, the popularity of AI has grown invariably. Specifically, it has made a considerable impact in the medical sector and oncologic treatment as well, due to a surge in electronic data, breakthroughs in technological infrastructure and groundbreaking research in deep learning neural networks. AI cancer treatment has demonstrated potential in improving liquid

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February 7, 2023

Medical Device CRO: An Opportunity to Look For

By Simriti Gupta Medical Device, Medical Devices and Technology  0 Comments

Over the past decade, numerous scientific and technological breakthroughs in the medical device CRO industry have resulted in an accelerated pace of research and innovation within this domain. Further, the demand for advanced and minimally invasive medical devices has been augmented due to the increase in expenditure on healthcare. However, one of the primary challenges

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February 6, 2023

SARM1 Inhibitor: A Solution Against Neurodegenerative Disorders

By Rohit Pareek Alzheimer's Disease, Alzheimer's Pipeline, Alzheimer’s Disease, Neurodegeneration, Parkinson’s Disease  0 Comments

Presently, several industry and non-industry stakeholders are evaluating SARM1 inhibitor as potential therapeutic agent for the treatment of neurological disorders across various preclinical studies and early stages of clinical development, worldwide. Given the encouraging research outcomes, the players in the SARM1 inhibitor market have received more than USD 10 million in grants, since 2014, from

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February 6, 2023

TCR T Cell Therapy: An Emerging Therapeutic Modality

By Ajay Kumar T-Cell Therapies, TCR therapies  0 Comments

Modified T-cell receptors or TCR T cell therapy is an emerging class of adoptive therapy that employs genetically modified lymphocytes to target specific tumor markers. Structurally, TCR is a heterodimer comprising of two different polypeptide chains, namely the α-chain and β-chain. TCR therapies’ tumor-cell killing efficacy may be primarily attributed to the fact that they

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February 3, 2023

Cell Therapy – The Revolutionary Therapeutic Modality: All Set To Obliterate Oncological Disorders

By Dhriti Gulati Cell Therapies, Cell Therapy, Manufacturing, Stem Cell Therapy, Stem Cells, T-Cell Immunotherapies, T-Cell Therapies  0 Comments

The American Society of Gene and Cell Therapy (ASGCT) defines cell therapy as a therapeutic modality that involves the administration of either normal or modified cells to patients for the treatment of various diseases. In this form of therapy, patients are injected with living and intact human cells that are deemed to be capable of

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February 2, 2023

4D Bioprinting Market: Key Trends

By Shreeya Agrawal 3D Bioprinting, 4D Bioprinting  0 Comments

What is 4D Bioprinting? 4D bioprinting refers to the addition of a fourth dimension that enables 3D printed structures to change their shape with time with the help of smart biomaterials, which have the tendency to morph in the presence of stimuli (such as, heat, water, light, electricity, magnetic energy, stress, strain, and pressure). Various

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February 1, 2023

Applications of Blockchain in Various Sectors: An Introduction

By Muskaan Arora Blockchain, Clinical Trials, Cybersecurity, Healthcare, virtual clinical trials  0 Comments

Introduction and Applications of Blockchain The term blockchain refers to the way it stores transaction data in blocks that are linked to form a chain. This technology is also known as Distributed Ledger Technology. Since every entry is stored as a block on the chain, the length of the chain increases as more transactions are

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January 31, 2023

Intracellular Drug Delivery – Future Potential

By Tanya Shastri CELL TARGETING, Drug Delivery, Targeting Therapies  0 Comments

Healthcare treatment is important for those having fatal diseases and so is the precision treatment in almost every case. One of such disease which has squabbled the entire humanity and accounts for the highest number of death rates globally is cancer. It’s a disease wherein the body’s abnormal cells grow uncontrollably and spread to other

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January 30, 2023

T Cell Therapy: The Future of Modern Cancer Treatments

By Ajay Kumar Cell Therapies, T-Cell Immunotherapies, T-Cell Therapies  0 Comments

Cancer is known to be one of the leading causes of deaths worldwide. In fact, as per the WHO, close to 10 million cancer related deaths were reported in 2020. Further, it is estimated that, by the end of 2040, 27.5 million new cancer cases will be added to the global numbers, exerting tremendous physical,

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January 23, 2023

Monkeypox Vaccine: Disease Overview, Transmission and Diagnosis

By Divya Nagla Viral Diseases  0 Comments

Monkeypox is a viral disease, which is usually transmitted to humans from animals. The disease is known to have symptoms similar to those observed in smallpox patients, although it is considered to be clinically less severe. In recent years, monkey pox has emerged as a prominent orthopox virus affecting public health. In May 2022, multiple

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January 18, 2023

Antiviral Drugs: Are we Prepared for the Next Viral Pandemic?

By Rohit Pareek COVID-19, COVID-19 Pandemic, Covid19, NOVEL DRUG  0 Comments

Infectious diseases are known to be one of the top 10 leading causes of deaths, worldwide. In-fact, more than 40 million people are affected by various types of infectious diseases annually. Further, it has been around three years since the COVID-19 pandemic hit the world, and yet, shows no signs of disappearing. An article published

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January 17, 2023

Artificial Intelligence Pathology: Transforming Medicine

By Ronit Sharma artificial intelligence, Diagnostics, Non-Invasive Diagnostics  0 Comments

How is Artificial Intelligence being used in Digital Pathology? Artificial intelligence in pathology is a transformative technology that has enabled pathologists to make the shift from visual inspection of tissue samples to automated image analysis. With the advent of AI pathology, researchers are now benefiting from computerized image analysis software that can draw conclusions and

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January 16, 2023

Self Testing Kits: A Transformation in Diagnostic Sector

By Simriti Gupta At-home Self-testing, Diagnostics, Non-Invasive Diagnostics  0 Comments

In the health industry, digitization has evolved over time with numerous advances to ensure that everyone has equitable access to health products and medical specialists.  Self testing kits have the ability to improve health equity and accelerate progress toward universal health coverage, and it has the capacity to alter health care. Self testing kits provide

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January 13, 2023

SARM1 Inhibitors: An Answer For Neurodegenerative Diseases

By Rohit Pareek Neurodegeneration  0 Comments

Neurological disorders are considered the second leading cause of death and the primary cause of long-term disability, worldwide. In fact, over 6.5 million neurological disorder related deaths are reported annually, globally. Further, according to a report published by the United Nation (UN), close to 1 billion people, across the globe, suffer from various types of

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January 12, 2023

Advancements in Automation of Processes: Key Value Driver for Escalated Interest in Cell Therapies Manufacturing Domain

By Dhriti Gulati Cell Therapies, Cell Therapy, Contract Manufacturing  0 Comments

Considering the vast potential of cell therapies in the treatment of rare disorders and sufficient body of evidence validating the clinical benefits / therapeutic potential of this complex class of biologic drugs, cell therapies have garnered considerable attention of players engaged in the healthcare industry, in the past few years. The focus of stakeholders has

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January 11, 2023

CAR-T Cell Therapy: Addressing Key Unmet Needs in Oncology

By Ajay Kumar Cell Therapies, Cell Therapy, T-Cell Therapies  0 Comments

Amidst the active initiatives undertaken to develop more targeted anti-cancer therapies, CAR-T therapies have emerged as a promising option, given their ability to eradicate tumor cells from the body with minimal treatment-related side effects. Further, CAR-T cell therapy, relatively recent addition to the gamut of anticancer interventions, has demonstrated significant promise. Overall, this highly specific

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December 13, 2022

Rising Need of Organ on a Chip Products And Technologies

By Simriti Gupta 3D Bioprinting, Healthcare  0 Comments

The process of drug development and safety testing is extremely expensive and time-consuming. Animal testing is a vital part of drug development process, which is beneficial for researchers in understanding the cause, diagnosis, and treatment of various medical conditions. However, there are several concerns over the validity of animal research; drugs that seem to be

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December 12, 2022

T Cell Immunotherapy: A New Paradigm in Cancer Treatment

By Ajay Kumar T-Cell Immunotherapies, T-Cell Therapies  0 Comments

Cancer is one of the leading causes of mortality, accounting for 0.6 million deaths in 2021, in the US alone. As per the International Agency for Research on Cancer (IARC), by 2040, there are likely to be 27.5 million new cases and 16.3 million deaths related to cancer, annually. Although cancer therapeutics continue to be

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December 12, 2022

Antibody Drug Conjugates Market: The Future of Novel Therapies

By Bhavishya Bhardwaj ADC Conjugation, ADC Cytotoxic Payloads, ADC Therapeutics, ADCs Pipeline  0 Comments

Antibody drug conjugates (ADCs) are an upcoming class of targeted therapeutic agents that have garnered the attention of pharmaceutical companies, and academic / research institutions across the world. Fundamentally, these complex biotherapeutic entities represent the combination of the target specificity of an antibody and the therapeutic features of a chemotherapy / cytotoxic drug. Such conjugates

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December 12, 2022

CAR T Therapy: Advancing Immune Cells to Treat Cancer

By Ajay Kumar Cell Therapies, T-Cell Therapies, Therapies  0 Comments

Cancer is known to be one of the leading causes of deaths worldwide. In fact, as per the WHO, close to 10 million cancer related deaths were reported in 2020. Further, it is estimated that, by the end of 2040, 27.5 million new cancer cases will be added to the global numbers, exerting tremendous physical,

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August 29, 2022

Spatial Genomics – An Amelioration of Tissue Analytics

By Nishta Garg Genomics, SPATIAL GENOMICS  0 Comments

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS kits), single-cell analysis, flow cytometry and mass spectrometry. These platforms, although widely adopted, require tissue fixation and are therefore not capable of providing

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June 2, 2022

DNA Cloning: A Step Towards Future of Genetics Science

By Tamanna Sharma DNA Cloning Market  0 Comments

Over the past decade, the field of synthetic biology has witnessed several advancements. DNA / gene cloning is the field of synthetic biology which can be helpful to understand the effect of mutation on a particular gene. Many diseases that can be treated using artificial DNA synthesis, such as leukemia and sickle cell anemia, involving

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May 12, 2022

Targeted Protein Degradation Market: Riding on the Popularity of PROTAC, Market is set to Grow Exponentially

By Gaurav Chaudhary Degradation Market  2 Comments

Over the years, the drug hunters have tried to target the tens of thousands of proteins responsible for sickness and health. But a vast majority of them have remained out of reach. While, the scientific evolution has led to the development of potent and selective small-molecule inhibitors of protein function, but still, multiple targets of

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May 3, 2022

Is Blue Ocean Strategy The Silver Bullet For Emerging Teleradiology Players to Achieve A Breakthrough In This Highly Competitive Market?

By Gaurav Raj Teleradiology Services Market  0 Comments

Blue ocean strategy, a concept first introduced in 2004, by W Chan Kim, and Renee Mauborgne in their bestselling book of the same name, talks about how to achieve a breakthrough in a highly saturated market by focusing on creating a new uncontested market. Blue ocean strategy is a systematic approach that helps emerging service

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May 2, 2022

Plant Based Protein: A Novel Advancement in Protein Expression

By Yuveena Singh Plant Host Systems  0 Comments

In the past few years, plants have been gaining a rapid traction, involving genetic modification and expression of new genes in plant host cells. Owing to significant advantages over conventional expression systems, such as low production costs, product safety, and ease of scaling up, plant based protein expression systems are being widely recognized as a

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April 26, 2022

Women’s Digital Health: A New Era of Female Healthcare

By Arun Gupta Women’s Digital Health  0 Comments

Women’s digital health involves the initiatives taken by industry stakeholders and researchers, which include technological remedies, such as mobile apps, software, wearable devices and diagnostic tools that exclusively aid in improving female health and wellness. Since it is primarily focused on women’s healthcare, it is termed as Female Technology or FemTech. The term “FemTech” was

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April 22, 2022

Sustainable Packaging: A Paradigm Shift in Healthcare Packaging

By Nobel Dhingra Healthcare Packaging  0 Comments

What is Sustainability and Why is Sustainable Packaging Important? The term sustainability is derived from the Latin word sustinere, which means to hold or support. Sustainable packaging is defined as packaging that is safe for individuals, as well as the environment, while meeting all requirements for performance, cost and ease of fabrication. Further, the product should be

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April 20, 2022

Pharmaceutical Packaging: The Rising Demand and Opportunities

By Rohit Pareek Pharmaceutical Secondary Packaging  0 Comments

On an average, around 50 drugs are approved by the US Food and Drug Administration (US FDA) annually. Further, studies indicate that more than 100,000 tons of pharmaceutical products are consumed globally per year. In addition, over the next five years, the global pharmaceutical contract manufacturing market is projected to grow at a CAGR of

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April 19, 2022

Single Use Sensors: A Step Towards Future Transformation

By Rupali Bhardwaj Single-use Technology  0 Comments

Over the past decade, the pharmaceutical contract manufacturing market has witnessed several advancements in terms of bioprocessing. Bioprocess technology is one of the integral parts of biotechnology that deals with different biological processes involving living or competent cells to get value added products at the end of the process. Recently, an increasing demand for various

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March 28, 2022

Continuous Manufacturing: Meeting the Demand for Drugs and API

By Tanya Shastri Continuous Manufacturing  0 Comments

Over the last few decades, the pharmaceutical contract manufacturing market has been using batch processes for production of pharmaceutical products, which is a multi-phase process. However, the surge in the demand for drugs due to COVID-19 has led the pharmaceutical industry to shift on to a more agile and flexible technique- continuous manufacturing, which is

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March 25, 2022

Metabolomics Testing: An Emerging Tool in Clinical Research

By Jayita Sood Metabolomics  0 Comments

Scientific fields involved in high throughput measurement of biological molecules are referred with the suffix-omics including, nutrigenomics, transcriptomics, genomics, proteomics and metabolomics testing. Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. Likewise, metabolomics testing involves the study of by products of metabolism.

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March 22, 2022

Subcutaneous Drugs: The Unmet Need in the Pharma Space

By Ronit Sharma Biologics  0 Comments

Over the years, the incidence and prevalence of chronic diseases, have increased significantly. Presently, the recommended treatment options for such clinical conditions are mostly biologics, which need to be administered via parenteral routes to ensure maximum therapeutic benefit. Given the inherent requirement for frequent medication, patients suffering from such long-lasting clinical conditions generally end up

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March 16, 2022

Exosome Companies: In-depth Look into Service Providers Market

By Aanchal Chaudhary Exosomes  0 Comments

Over the years, applications of exosomes in therapeutics have undergone an evolutionary change, in terms of cost of research, technology used, and duration of the study. Moreover, various exosome companies have entered into collaborations in order to advance their innovations and offer specialized research expertise, services and technologies. In order to promote the use of

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March 14, 2022

Pharmaceutical Excipients – Current Scenario and Future Trends

By Arun Gupta Biopharmaceutical  0 Comments

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical products are currently

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March 11, 2022

Exosomes: A Trending Term in Therapeutic Domain

By Aanchal Chaudhary Exosomes  0 Comments

Exosome Therapy has been of great interest in the recent years due to the discovery of their potential in so many research and analytic procedures. Exosomes are known to have some unique functions, such as their ability to alter recipient cell bioactivities, acting like intercellular messengers and also having therapeutic potential in disease diagnostics as

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March 10, 2022

Pharmaceutical Excipient Market: Current Scenario and the Future

By Pemba Lahmo Biopharmaceutical  0 Comments

Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines, and gene therapies), by the US FDA, have steadily risen. In fact, over 8,000 biological pharmaceutical excipient products are

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March 7, 2022

Complement Therapeutics: Treating Complement-Related Diseases

By Diksha Agarwal Complement Therapeutics  0 Comments

Complement System:  Key Component of Complement Therapeutics Complement system was discovered in 19th century as a part of immune system responsible for tissue repair and homeostasis, thereby providing first line of defense against multiple infections. This complete process is in association with a complex and highly regulated assembly of proteins which involve several soluble and

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March 4, 2022

Next Generation Therapeutics: Novel Therapies for Rare Diseases

By Diksha Agarwal Complement Therapeutics  0 Comments

Since the approval of Soliris® in 2007, an anti-C5 antibody, the field of complement drug discovery has gained significant attention. Currently, nine complement therapeutics are commercially available, while around 190 molecules are under development for various disease indications. Some of the complement therapeutics, namely Berinert®, Cinryze®, ORLADEYO®, Ruconest® and TAKHZYRO® were approved for the treatment

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March 3, 2022

Peptide Pills: Addressing Key Unmet Needs Across Diseases

By Simriti Gupta Oral Protein  0 Comments

Orally administrable protein / peptide pills offer several advantages including, effective treatment of numerous clinical conditions and degenerative disorders. Interestingly, recent advances in this domain have led to the development of several treatment strategies that, according to developers, exhibit the necessary capabilities to overcome challenges posed by traditional oral formulations  and peptide pills. One of the

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March 2, 2022

Intranasal Drugs: An Alternate Route of Administration

By Bhavishya Bhardwaj Intranasal Therapeutics  0 Comments

The intranasal drugs delivery is widely accepted as effective and non-invasive option for the local and systemic delivery of several types of active pharmaceutical ingredients (API). Majority of such formulations are designed to treat chronic obstructive pulmonary disorders (COPD), asthma and other respiratory diseases. Interestingly, over the past few years, drug developers focused on non-respiratory

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February 28, 2022

Container Closure Integrity Testing for Pharmaceutical Industry

By Ridhima Gupta integrity testing  0 Comments

Over the past few years, the pharmaceutical industry is growing a tremendous pace. Considering patient’s health and safety, the drug products are expected to be free from microbial contamination and should be safe for use throughout the drug’s life cycle. Therefore, several quality checks are performed to ensure product’s sterility and stability. One of the

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February 25, 2022

DNA Replication Demand: Driving Contract Manufacturing Market

By Dhriti Gulati Oligonucleotides  0 Comments

Since the approval of the first antisense therapy in 1998, DNA replication has been in light for their capabilities as therapeutic agents. DNA replication provides a short synthetic nucleotide chain with immense potential in the diagnosis and treatment of a myriad of disease indications. In addition to therapeutics, these complex molecules act as a significant

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February 24, 2022

Next Generation Sequencing: Revolutionizing the Field of Genetics

By Arun Gupta Next Generation Sequencing  0 Comments

Next generation sequencing has emerged as an evolutionary technology in modern biotechnology and healthcare research, enabling researchers to better understand the cause and consequences of disease and develop next generation drug conjugates. Over the past few years, several companies have started offering a diverse range of genome sequencing products and services using various second and

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February 23, 2022

Auto Injector: The Rising Need

By Ishita Nanda Autoinjectors  0 Comments

With the increasing global population, the incidence rates of several chronic disease indications, such as diabetes, anaphylaxis, rheumatoid arthritis and psoriasis, are on the rise. This has led to a rise in the demand for effective treatment options for patients suffering from these diseases. Further, in order to improve the quality of life in these

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February 22, 2022

NGS Library Preparation Kits: Current Scenario and the Future

By Arun Gupta Next Generation Sequencing  0 Comments

Since the introduction of a gene sequencing method by Frederick Sanger in 1977, the field of genomic data collection and analysis has evolved significantly. Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as next generation drug conjugates and personalized medicine. However, the conventional nucleotide library preparation process

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February 21, 2022

Nanoparticles: Emerging Stars for Pharmaceutical Industry

By Yash Kumar Nanoparticles  0 Comments

Over the last decade, one of the major challenges faced by pharmaceutical players across the globe is low drug solubility. In fact, it has been observed that around 40% of the pharmaceutical products approved by regulatory organizations exhibit poor bioavailability / solubility. Further, every year, poor bioavailability is one of the prime reasons that leads

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February 19, 2022

Oligonucleotide Therapeutics: A Driving Force for CMOs

By Dhriti Gulati Oligonucleotides  0 Comments

In the 20th century, major research went into discovery of a therapeutic class with the primary purpose of interfering with the RNA expression linked to disease causing proteins, nowadays classified as Oligonucleotide therapeutics. These short, single-stranded DNA or RNA molecules, which are the product of DNA manufacturing services, have various applications in biopharmaceutical and biotechnology

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February 17, 2022

Integrity testing: Shift in Trend for Container Closures

By Ridhima Gupta integrity testing  0 Comments

In earlier times, container closure integrity testing was not regarded as an essential step in the process of manufacturing. The company developing drug product through such an intense process, use to consider container closure system only for packaging of the product. However, gradually it was realized that container closure integrity testing is a key factor

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February 16, 2022

Gene Editing Technology: ZFN, TALEN and Meganucleases

By Ishita Nanda Genome Editing Techniques  0 Comments

Presently, there are several companies and universities, which are exploring the potential of gene editing technology beyond CRISPR for basic research, and the development of gene editing solutions. With the development of a versatile gene editing technology, including zinc-finger nucleases (ZFNs), TAL effector nucleases (TALENs), engineered endonucleases / meganucleases (EMNs) and clustered regularly interspaced short

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February 15, 2022

ADC Payload / Warheads and Rise in its Demand

By Ishita Nanda ADC Cytotoxic Payloads  0 Comments

With six approved drugs, namely POLIVY™ (2019), LUMOXITI™ (2018), BESPONSA® (2017), MYLOTARG™ (2017, reapproval), KADCYLA® (2013) and ADCETRIS® (2011), and more than 300 candidates in the pipeline (clinical / preclinical stages), antibody drug conjugates (ADCs) have emerged as a promising class of therapeutics for the treatment of various disease indications. Over time, medical researchers have

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January 4, 2022

Clinical Trial Management: Clinical trial site management landscape

By Rohit Pareek CLINICAL TRIAL PLANNING, Clinical Trials, Site Management Organizations, virtual clinical trials  0 Comments

Clinical trials form an integral part of the overall drug development process, enabling the necessary evaluation of the safety and efficacy of a drug candidate. Studies suggest that around 40% of the total investment made for the development of drug candidate is dedicated to clinical trials; this is equivalent to an expenditure of USD 78

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January 3, 2022

At Home Blood Collection: New Era of Diagnosis and Testing

By Simriti Gupta AT-HOME BLOOD COLLECTION, HOME BLOOD COLLECTION  0 Comments

In the era of COVID-19, where the world is looking for point of care treatment, in order to avoid maintain physical distance. Post the onset of COVID-19 pandemic, there has been a decline in number of patients visiting laboratories for sample collection and testing. To avoid risk of infections, patients have postponed their routine tests

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December 23, 2021

Treg Cell Therapy: A Hotspot in the Field of Immunotherapy

By Ravneet Kaur Cell Therapies, Cell Therapy, T-Cell Therapies  0 Comments

Classification of Treg Cell Therapy The Treg cell therapy (Tregs) is a therapeutic modality based on the mature subpopulation of T-cell therapy that plays a critical role in mediating immunological tolerance to self-antigens and suppress immune responses that are harmful to the host, thereby, enabling homeostasis. These mainly develop in thymus from CD4+ thymocytes and

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December 15, 2021

Site Management Organization: A Trend in the Clinical Trial Domain

By Rohit Pareek Clinical Practice, CLINICAL TRIAL PLANNING, Clinical Trials, Site Management Organizations, virtual clinical trials  0 Comments

Innovators in the pharmaceutical industry are constantly developing ways to improve the process of conducting clinical trial management. Amidst other alternatives, outsourcing various trial operations to a specialized service provider, such as site management organization, has emerged as a viable option for various developers. The advantages of engaging such specialized service providers are numerous and

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December 14, 2021

BLOOD COLLECTION AT HOME: IMPACT AND TRENDS

By Simriti Gupta AT-HOME BLOOD COLLECTION  0 Comments

Earlier, approaches used for blood collection were invasive, time consuming and needed a healthcare expert. However, in recent years, the methods for blood collection at home are evolving at a rapid pace. According to research study, 69% of participant were found to take part more likely in clinical trials, if they are able to provide

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December 13, 2021

DNA DATA STORAGE: RESEARCH LANDSCAPE AND FUTURE

By Mansi Dhingra DATA STORAGE, DNA Encoded, DNA Manufacturing  0 Comments

DNA data storage involves encoding and decoding binary data to and from synthesized strands of DNA. It offers generous, long-lasting, and stable data storage solution with orders of magnitude relatively higher than current storage mediums. Owing to the numerous benefits offered by DNA data storage as compared to other mediums, it is anticipated that this

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December 10, 2021

HER2 Targeted Therapy: Market Landscape and Future Potential

By Ishita Nanda Anti-cancer, Anti-cancer Therapy, Cancer, cancer therapeutics, Targeting Therapies  0 Comments

The epidermal growth factor receptor (EGFR) is a tumor resistance biomarker which plays an essential role in the differentiation and proliferation upon activation through the binding of one of its ligands. A non-ligand-binding member of EGFR family, HER2 exerts its activity through heterodimerisation along with its other family members. HER2 targeted therapy affects the transmembrane

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December 9, 2021

BIOPRESERVATION MEDIA INDUSTRY: A RISING MARKET

By Prachi Bhalla 3D Cell Cultures, BIOPRESERVATION  0 Comments

Biopreservation is the exclusive biological approach designated for the preservation of cells, tissues and organs ex-vivo for the purpose of storage, shipment and transportation. Biopreservation media is one of the most crucial entity in conferring effectiveness. The selection of the type of media depends upon the considerable time duration desired for the storage, type of

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December 1, 2021

Bioassay Services – A Prerequisite for the ATMPs Development

By Vaibhav Singh Bioassay, Cell Therapies, Gene Therapies  0 Comments

Bioassay Services – A Prerequisite for the Cell and Gene Therapy Development Over the past few years, investigational new drug (IND) filings by cell and gene therapy companies have significantly increased. In fact, from year 2016 to 2020 more than 300 IND filing for cell and gene therapy product have been recorded, indicating that several

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November 24, 2021

Rising Need of Wearable Injection Device Platform

By Rupali Bhardwaj Injectors, Injectors Market, WEARABLE INJECTORS  0 Comments

With the increasing global population, the incidence rates of several chronic disease indications, such as diabetes, heart disorders, neurological disorders and oncological disorders, are on the rise. This has led to a rise in the demand for effective treatment options for patients suffering from these diseases. Further, in order to improve the quality of life

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November 17, 2021

Pharmaceutical Vials Witnessing High Demand in Pandemic

By Simran Kaur COVID-19 Pandemic, Pharmaceutical Packaging, Pharmaceutical Vials, SUSTAINABLE PACKAGING  0 Comments

Over the years, advances in drug / therapy development processes have led the pharmaceutical industry to gradually shift from a one-drug treats all model to a more personalized approach of treatment. The growing complexity of modern pharmacological interventions, such as monoclonal antibodies, and cell and gene therapies, has further prompted the drug developers to develop

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November 16, 2021

Fc Fusion Protein – A New Approach to Drug Therapy

By Mansi Dhingra Antibody Discovery, Antibody Drug, Antibody Humanization, FUSION THERAPEUTICS  0 Comments

Since the approval of Enbrel®, CD4 – Fc fusion protein (for the treatment of rheumatoid arthritis) in 1998, Fc fusion protein therapies have evolved into a prominent class of therapeutics. Currently, 13 Fc fusion protein based drugs are commercially available, while around 50 molecules are under development for various disease indications. Some of the Fc fusion

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November 11, 2021

Pharmaceutical Glass Vials: Current Scenario and Future Trends

By Simran Kaur Pharmaceutical Packaging, Pharmaceutical Vials, SUSTAINABLE PACKAGING  0 Comments

Primary packaging material (e.g. Pharmaceutical Glass Vials) plays a crucial role in preserving the stability, efficacy and safety of the drug as it is in direct contact with the packaged therapeutic. Additionally, pharmaceutical primary packaging material assists in maintaining the sterility and quality of a drug product, while also providing information related to its identity

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November 10, 2021

ADC Therapeutics – Alternative to Traditional Anticancer Therapies

By Ishita Nanda ADC Conjugation, ADC Therapeutics, ADCs Pipeline, Antibody Discovery, Antibody Drug, Antibody Humanization, Antibody Purification  0 Comments

Antibody-drug conjugates (ADCs) are an upcoming class of targeted therapeutic agents that have captured the attention of both large and small pharmaceutical companies, and academic / research institutions from all across the world. Fundamentally, these complex biotherapeutic entities demonstrate the combination of target specificity of an antibody and therapeutic features of a chemotherapy / cytotoxic

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November 8, 2021

Glycoengineered Antibodies – Virtue of enhanced effector functions

By Chaitanya Anand Antibodies, Antibody Discovery, Antibody Drug, Antibody Purification, Glycoengineered Antibodies  0 Comments

With close to 100 approved monoclonal antibodies, and over 550 molecules in the clinical pipeline, antibody based pharmacological interventions have become one of the fast growing segment of the biopharmaceutical industry. In fact, these interventions are anticipated to generate a cumulative sales of USD 300 billion by 2025. Further, within the antibody therapeutics industry, engineered

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November 1, 2021

ADC Therapy – A Potential Tool Against Cancer

By Ishita Nanda ADC Conjugation, ADC Therapeutics, ADCs Pipeline, Antibodies, Antibody Drug  0 Comments

Over the years, various technological advancements, such as antibody engineering for site-specific conjugation and enhanced pharmacokinetic and pharmacodynamic properties, have paved the way for antibody drug conjugates to be recognized as potent therapies (ADC therapy) targeting a wide range of indications, including solid tumors and hematological malignancies. ADC therapy is an engineered therapy comprised of

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October 28, 2021

Green Packaging: Paramount for Pharmaceutical Sector

By Nobel Dhingra Pharmaceutical Packaging, SUSTAINABLE PACKAGING  0 Comments

Green Packaging in pharmaceutical secondary packaging industry plays a crucial role in ensuring the sterility and quality of a drug product, while it also provides information related to its identity and, in certain cases, dosing instructions. Pharmaceutical packaging is typically carried out under Packagingcontrolled conditions; specifically, for therapeutics that are designed for parenteral administration, fill

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October 26, 2021

Alzheimers Treatment and Its Evolving Market

By Sunidhi Thakur Alzheimer's Disease, Alzheimer's Pipeline, Alzheimer’s Disease  0 Comments

Alzheimer’s disease is a progressive neurological disorder characterized by the death of brain cells, eventually leading to memory loss, cognitive dysfunction and dementia. Accounting for 60-70% cases of dementia, Alzheimer’s disease is known to be the sixth leading cause of death in the US.   Presently, more than 6 million Americans of all ages are living

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October 25, 2021

Cell Therapy Packaging Market – Importance and Future Potential

By Shivangi Anand Cell Therapy, Pharmaceutical Packaging  0 Comments

Over the years, the pharmaceutical industry has witnessed several advancements in drug development. It has gradually shifted from a one-drug treats all model to a more personalized approach of treatment, which involves the use of personalized cell and gene therapies for various disease indications. This shift has led to an evident change in the pharmaceutical

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October 22, 2021

Progressive Supranuclear Palsy: A Tough Nut to Crack

By Ishita Nanda Supranuclear Palsy  0 Comments

Since John Steele, John Richardson, and Jerzy Olszewski first described Progressive Supranuclear Palsy (PSP) in 1964, the neuroscience community has been on the lookout to find a “miracle molecule” or an “elixir” that can cure patients diagnosed with this debilitating disease. With more than 2,000 research studies published so far, the progressive supranuclear palsy domain

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October 12, 2021

Teleradiology Services: The Need During COVID-19 Pandemic

By Gaurav Raj artificial intelligence, Digital Therapeutics, Patient Monitoring, TELERADIOLOGY  0 Comments

Teleradiology services is a branch of telemedicine that uses telecommunication systems for the transmission of radiological images from one location to another. Additionally, it helps the radiologists to interpret various types of images, such as computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), ultrasound, and X-rays, remotely. As of late, teleradiology have

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September 27, 2021

Bioprocess Automation: A Step Towards Digital Transformation

By Ridhima Gupta BIOPROCESS AUTOMATION  0 Comments

In the era of digitalization where the world is looking forward towards automating their manufacturing process, the bioprocess industry took a while to adopt the automation technology. The biopharmaceutical industry came across several obstacles while adopting the automated technology. Examples of which include, complexity of the processes and delicacy of the living cells and organisms

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September 23, 2021

Drug Reconstitution Systems: Reconstitution of Drug and Delivery

By Diksha Agarwal Drug Delivery, Drug Reconstitution  0 Comments

The novel drug reconstitution systems have emerged as a promising alternative to traditional methods of reconstitution, adding significant value to the storage and transfer of lyophilized therapeutics. These systems enhance the portability, efficiency and optimum delivery of the lyophilized drugs and have the potential to reduce the number of steps significantly, which enable the dilution

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September 21, 2021

Bioprocess Controllers and Automation: Key Facts and Trends

By Ridhima Gupta BIOPROCESS CONTROLLERS  0 Comments

For more details, you can also download the SAMPLE REPORT on bioprocess controllers by Roots Analysis. Our Social Media Platform

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September 20, 2021

Reconstitution Medication: Reconstitution of Lyophilized Drug

By Diksha Agarwal Drug Reconstitution, NOVEL DRUG  0 Comments

Lyophilization of Pharmaceuticals and Reconstitution Medication In 2018, seven out of ten top-selling prescription medicines were biologics. The liquid formulations of biologics are not much stable and tend to loose efficacy with time due to the changes in their pharmacokinetic and pharmacodynamic properties. Therefore, lyophilization of such drugs is essential before their storage. Around 50%

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September 14, 2021

CMO Manufacturing and The Rising Adoption of Novel Processes

By Simriti Gupta BIOMANUFACTURING, Contract Manufacturing, Manufacturing  0 Comments

Recent developments in pharmacology and biotechnology have been able to drive significant advances and innovation in understanding the root causes of various diseases; this has further aided in the discovery and development of more targeted treatment strategies. It is worth noting that such advances in the healthcare industry have made pharmaceutical development and CMO manufacturing

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September 8, 2021

Squamous NSCLC Market: An Emerging Treatment Modality

By Abhishek Dogra CANCER MARKET, Immunotherapy  0 Comments

Over the years, a number of targeted therapies have been developed for the treatment of various type of cancers, with the primary focus on the safety and efficacy of the treatment. The uncontrolled growth of cells originating in the bronchi lining, bronchioles or alveoli of the lungs is termed as lung cancer. Around 85% of

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September 2, 2021

Clinical Trial Design: What Does the Future Hold?

By Bhavishya Bhardwaj CLINICAL TRIAL PLANNING, Clinical Trials, virtual clinical trials  0 Comments

Over the years, clinical research has undergone an evolutionary change, in terms of cost of research, technology used, and duration of the study. It is worth highlighting that clinical research involves two major steps, namely study design and study reporting. Further, study design involves three key steps, theoretical design, data collection design and statistical analysis

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August 17, 2021

Pharma CMO: The Solution to Production of Complex Substances

By Simriti Gupta Contract Manufacturing, Manufacturing, Market Research, Pharmaceuticals  1 Comment

The inherent expertise of CMOs and CDMOs is believed to be capable of enabling reduction in the time-to-market a product, significant cost-benefits, as well as access to larger production capacities and novel technologies.  It is worth mentioning that there has been substantial merger and acquisition activity in the pharma CMO market in the past few

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July 12, 2021

Phage Display Libraries: Where do we stand?

By Sunidhi Thakur Display Library Technologies  0 Comments

Over time, a variety of methods / approaches have been developed for the generation of viable therapeutic leads. These include the hybridoma technology, B-cell cloning, transgenic animal-based techniques, in vitro display methods (using phage display, ribosomes, mRNA, and cDNA) and cell surface display methods (involving mammalian, yeast, and bacterial cells). Despite being responsible for the

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June 29, 2021

TPD – Targeted Elimination of Disease Causing Proteins

By Nancy Kapila Target Protein Degradation  0 Comments

Targeted protein degradation (TPD) is an emerging therapeutic modality that has the potential to enable the treatment of difficult-to-treat diseases. While conventional medicines, such as small molecule inhibitors and monoclonal antibodies, address fewer than 20% of the proteome, TPD offers a unique means to tap into the rest of the vast, unexplored proteome. Through TPD,

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June 22, 2021

Continuous Manufacturing System Providers

By Shivangi Anand BIOMANUFACTURING, Contract Manufacturing, Manufacturing, Microbial Manufacturing  0 Comments

Over the years, several industries have implemented evolutionary changes in their respective manufacturing processes. One to the most rewarding advancements in this direction, is process automation. In pharmaceutical contract manufacturing, the automation of various aspects of the production process has led to the establishment of the continuous manufacturing system providers. However, the transition to continuous

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June 21, 2021

Polycystic Ovary Syndrome (PCOS)

By Nancy Kapila Polycystic Ovary Syndrome  2 Comments

Polycystic Ovary Syndrome is a condition in which the ovaries produce abnormal amount of androgens (males sex hormones), higher than the amount usually present in a woman with normal ovaries. The ovaries develop fluid filled sacs, known as follicles, which contain an immature egg. However, in polycystic ovary syndrome, none of the eggs mature and

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June 16, 2021

Cell Line Development: An Ocean of Opportunities for Stakeholders

By Jasparam Kaur 3D Cell, 3D Cell Cultures, Cell Line, Cell Line Development, Cell Therapies, Cell Therapy  1 Comment

The growing pipeline of monoclonal antibodies, vaccines, enzymes, biosimilars and other therapeutic proteins have created an ever- increasing demand for highly- productive and stable cell lines. Many of the recombinant biotherapeutic products, produced in cellular systems, have been translated into commercial successes; these include ALPROLIX®, ELOCTATE® and ELAPRASE®.  Given their impact on the overall quality

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June 15, 2021

Modular Cleanroom: A Paradigm Shift in Pharmaceutical Facilities

By Yuveena Singh BIOMANUFACTURING, Contract Manufacturing, DNA Manufacturing, Manufacturing, Microbial Manufacturing, MODULAR FACILITIES, Vector Manufacturing  1 Comment

The concept of modular cleanroom has long been employed in other sectors, but it has only recently acquired traction in the pharmaceutical business over the last two to three decades. Modular cleanroom construction is a process wherein factory-produced, pre-engineered building units, which are constructed offsite under controlled plant conditions, are assembled on site to construct

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June 14, 2021

Intracellular drug delivery – solution to undruggable targets

By Chaitanya Anand Modern pharmaceutical industry  1 Comment

Over time, advances in molecular biology and pharmacological chemistry have enabled the identification of biological targets localized in the subcellular space, and development of therapeutic leads against them. In fact, there are several clinical conditions, which were previously considered undruggable since the traditional small molecule-based interventions were unable to penetrate the selectively permeable cell membrane.

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June 11, 2021

Antibody Purification: The Service Providers Landscape

By Ishita Nanda Antibody Drug, Antibody Purification  0 Comments

Over time, several innovative technologies have been developed to support the designing and manufacturing of various types of antibody products; however, the aforementioned processes are characterized by high costs and technical complexities, especially during the production and downstream processing steps. Therefore, it is challenging for new entrants and companies with limited resources and capital, to

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June 10, 2021

Antisense Oligonucleotides – Gene Silencing Revolutionized

By Mansi Dhingra Antisense Oligonucleotide, Oligonucleotides  1 Comment

Oligonucleotide (commonly referred to as oligos), are short single stranded DNA or RNA molecules, typically containing 15-20 nucleotide residues.[1],[2] In the modern biopharmaceuticals and biotechnology, the applications of these molecules are vast, including (but not limited to) genetic testing, fundamental biomolecular research, and forensic analysis. Antisense oligonucleotides are a diverse class of therapeutics that are

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June 9, 2021

Fibrotic Disease Diagnosis: A Step Towards Painless Detection of Fibrosis

By Ishita Nanda Non-Invasive Diagnostics  1 Comment

Advances in the field of biotechnology have enabled the development of several minimally invasive / non-invasive approaches for diagnosis of fibrotic disease which include imaging diagnostics and biomarker-based assays. Among the biomarker-based tests, liquid biopsy (based on the analysis of biofluids such as blood, urine and / or plasma), a relatively new concept, has emerged

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June 8, 2021

STING Pathway Targeting

By Shivangi Anand Market Research, STING Pathway  1 Comment

Stimulator of interferon genes or STING, discovered by the laboratory of Glen N Barber in 2008, is one of the signaling proteins that is responsible for the transcription of genes associated with the innate immunity of an individual. Amidst the recent COVID-19 pandemic, it has become even more essential to strengthen the immune system. The

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June 7, 2021

Immunocytokines – The Power of Fusion Proteins

By Ishita Nanda Immunocytokines, Market Research, Proteins  1 Comment

Cancer is one of the leading causes of death worldwide, accounting for an estimated 0.6 million deaths in 2020, in the US alone. The World Health Organization has estimated the number of new cancer cases to rise by 70%, worldwide, over the next 20 years. It is a well-known fact that the conventional treatment options,

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March 2, 2021

Virtual Clinical Trials: The Present And Future Of Pharma Research

By Simriti Gupta Clinical Trials, virtual clinical trials  1 Comment

The lack of patient centricity in traditional clinical trials is known to inhibit trial sponsors to retain enough patients, which is critical to successfully complete safety and efficacy evaluations of novel therapeutic interventions on predetermined completion dates. In addition, the lack of participant compliance in clinical trials often leads to massive delays which are known

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February 26, 2021

Biopharma CRO: Fueling the research of novel biologics

By Bhavishya Bhardwaj Biopharmaceutical, Contract Research Organizations, Contract Service Providers  1 Comment

Biologics, often referred to as biopharmaceuticals or large molecules, are manufactured in the biological system, such as microorganisms, plants, or animal cells. Biologics contract manufacturing organizations represent one of the fastest growing segments of the pharmaceutical industry. This can be attributed to the rapid pace of innovation in this field, driven by the need for

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February 16, 2021

Biologics CMO: Industry Outlook and the Growing Pipeline

By Jasmeet Bhalla BIOMANUFACTURING, Contract Manufacturing, Manufacturing, Microbial Manufacturing, Vector Manufacturing  1 Comment

The recent years have portrayed the renaissance in the domain of biologics, as pharmaceutical industry has once again gained attention towards the production of bioproducts. In fact, in 2019, a total of 28 biopharmaceutical products (including monoclonal antibodies, recombinant proteins and gene therapy) were approved in the US. Further, over 8,000 biological pharmaceutical products are

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February 15, 2021

Digital Biomarkers: The Incessant Rise in Demand

By Yash Kumar Biomarkers  0 Comments

Biomarkers or biological markers are distinctive physiological features in an individual, which can be detected and quantified in order to gain insights about health and disease, one common example is a cancer biomarker, marking the presence of malignant cells within the body. On the other hand, digital biomarkers are defined as digital means that are

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February 9, 2021

Artificial Intelligence in Drug Discovery

By Ajay Kumar artificial intelligence, Drug Discovery  0 Comments

Drug discovery is a complex process which involves significant utilization of time and resources. As per several sources, on an average, the entire drug development process (from initial proof-of-concept to commercial launch) takes around 10-15 years and capital investments worth USD 4-10 billion to develop a drug from concept to commercial launch. The early stages

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February 4, 2021

mRNA Vaccines: What Lies Ahead?

By Avin Kakkar mRNA, Vaccines  1 Comment

Messenger RNA (mRNA) is a single-stranded molecule, which is complementary to the DNA strands of a gene. It plays a prominent role in the process of protein engineering, wherein mRNA is responsible for transferring genetic information from DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. In the last

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February 3, 2021

AI in Drug Discovery: Advancing Healthcare

By Ajay Kumar artificial intelligence, Drug Discovery  0 Comments

Artificial Intelligence have demonstrated intelligent behavior through their ability to learn, communicate with its users and solve complex problems using highly sophisticated algorithms. AI in drug discovery technologies have continued to evolve rapidly, with several industries increasingly deploying such solutions across key aspects of value chain. Furthermore, artificial intelligence in drug discovery is also made

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January 6, 2021

Antibody Drug Conjugates Manufacturing: How Are the Contract Manufacturers Supporting the Growing Demand

By Gaurav Chaudhary ADC Conjugation, ADC Therapeutics, ADCs Pipeline, Antibody Drug, Therapeutics  1 Comment

Antibody Drug Conjugates (ADCs) manufacturing known as the 21st Century Magic Bullets, have emerged as a promising class of targeted therapies being developed for the treatment of cancer. Two decades ago, in the year 2000, the domain witnessed the approval of first ADC known as Mylotarg®, by the US FDA.  This was followed by the

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December 21, 2020

Single Cell Technologies: A New Era of Gene Expression Analysis

By Simriti Gupta Market Research, Pharmaceuticals, SINGLE CELL SEQUENCING  1 Comment

For developing an improved understanding of the interactions of individual cells within their microenvironment, advanced molecular probing solutions are being used by researchers across the globe. In this context, high-throughput single cell technologies, have emerged as a powerful analytical technique for studying individual cells, enabling researchers to study gene expression at single cell resolution. Single

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October 27, 2020

Real World Evidence: Fighting COVID-19 Pandemic

By Nancy Kapila COVID-19, Market Research, Pharmaceuticals, Real World Evidence, RWE  1 Comment

With the ongoing pandemic of COVID-19, there is long wait for the vaccine to be approved. Even after the vaccine gets approved, there is no assurance of the complete eradication of virus. There will still be percentage of people who contract the illness. Therefore, it is very important to trace and detect the treatments in

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October 26, 2020

Microbial Fermentation: Growing Microbial-Based Biologics Pipeline

By Simriti Gupta BIOMANUFACTURING, Contract Manufacturing, Manufacturing, Microbial Biopharma Industry, Microbial Manufacturing  1 Comment

The recent years have portrayed the renaissance in the domain of microbial fermentation, as microbial biopharma industry has once again gained attention towards the production of biologics using microbial expression system. The modification and innovation in the microbial fermentation based expression systems for the production of various biologics have side-lined some of the earlier concerns

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October 20, 2020

RWE: THE GAME CHANGER IN DRUG DEVELOPMENT

By Nancy Kapila DRUG DEVELOPMENT, Pharmaceuticals  1 Comment

While the definition of real world evidence (RWE) is still evolving, most proponents associate it with data that is derived from medical practice among heterogeneous sets of patients in the real world setting. It is the integration of data gathered from various sources, such as EHRs, medical charts, patient claims and billing activities, product and

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October 19, 2020

Handheld Ultrasound Scanner: Revolutionizing Diagnostic Imaging

By Ronit Sharma Diagnostics, Market Research, Ultrasound  0 Comments

Advancements in the field of disease diagnostics have led to development of point of care diagnostics market; handheld ultrasound scanner has emerged as a novel solution to cater to unmet need in this domain. The handheld ultrasound scanner is the lightest portable ultrasound device, which permits patient diagnosis from a single transducer and transmit images

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October 14, 2020

3D Cell Culture: Rejuvenation amidst COVID-19

By Abhishek Dogra 3D Cell, 3D Cell Cultures, COVID-19, Market Research  1 Comment

As per the experts, one of the key reasons for the failure of therapeutic candidates in clinical trials is the use of conventional 2-dimensional (2D) cell culture systems in early research studies. Source for the featured image is https://pillreports.net/ Pillreports is a global database of Ecstasy” pills based on both subjective user reports and scientific

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October 13, 2020

Digital Therapeutics: Key Concepts to Tackle COVID-19 Pandemic

By Yash Kumar COVID-19, Digital Therapeutics, Therapeutics, therapeutics market  1 Comment

Digital therapeutics are clinically validated applications / software / online programs that have demonstrated the capability to facilitate positive outcomes when used in the prevention / treatment / management of diseases / clinical conditions. These therapeutics are designed to engage patients in personalized treatment or disease prevention programs, through mediating behavioral or psychological modifications, providing

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October 12, 2020

Intranasal Drugs: A Deeper Look into Service Providers Landscape

By Ankita Kashyap Inhaled and Intranasal Drug Delivery, Market Research, Pharmaceuticals, Service Providers  1 Comment

The techniques used for the drug delivery are found to be have an enormous impact on the efficacy of the treatment. In fact, the slow progression of the efficacy, has suggested the need of different approaches for the effective delivery of drug (such as intranasal drugs) to the target area, along with the optimal bioavailability.

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October 7, 2020

Targeted Drug Delivery System: Improving the Efficacy of Biologics

By Gaurav Chaudhary Biologics, Drug Delivery, Medical Device, Medical Devices and Technology  1 Comment

The gradual shift of healthcare industry towards the development of biologics is a well-known fact. Owing to this shift, there are over 1,000 cell and gene therapies which are being developed for the treatment of various disorders, majority of them being oncological disorders, cardiovascular disorders and neurological disorders.  Additionally, over the last decade, multiple immunotherapies

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September 17, 2020

Disposable Bioreactor on Rescue for COVID-19 Research

By Arun Gupta Bioreactors, COVID-19  1 Comment

The development of disposable bioreactor, also called a single use bioreactor, started nearly 40 years ago in 1980s. It was around this time that the bio-processors began to use plastic film bags to culture cells, which were initially designed for food storage and culture media containment. Moreover, incremental evolution of the concept of disposable technologies

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September 8, 2020

Radiopharmaceutical Manufacturing : Radioactivity In Healthcare

By Gaurav Chaudhary RADIOPHARMACEUTICALS  1 Comment

Fostered by partnerships between national laboratories, academia, and the pharmaceutical industry, the field of nuclear medicines and radiopharmaceutical manufacturing industry has evolved over the past few decades, in parallel with advances in imaging instrumentation, radionuclide production, and radiopharmaceutical development. Nuclear reactors and particle accelerators are presently used to produce a wide array of radionuclides for

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September 7, 2020

Microbial Fermentation Companies: Impact of the Pandemic

By Simriti Gupta Contract Manufacturing, Microbial Manufacturing  1 Comment

Since the discovery of recombinant DNA technology, several types of microbes have been established as a versatile biomolecule expression system. This can be attributed to the ease of handling of microbial cell lines, which are considered less fragile (compared to cells of higher eukaryotes); rendering them a popular choice for manufacturing operations. Moreover, incremental evolution

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August 11, 2020

Drug Repurposing – A Deeper Look into Service Providers Market

By Jasmeet Bhalla Drug Repurposing, Service Providers  1 Comment

Over the past decade, several scientific and technological breakthroughs in the drug repurposing industry have resulted in an accelerated pace of research and innovation within this domain. Further, the demand for effective repurposed drugs in the on-going war with the pandemic, is on the rise. However, one of the primary challenges faced by this industry

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July 31, 2020

Antibody Manufacturing Outsourcing Activities

By Simriti Gupta Market Research, therapeutics market  1 Comment

In recent years, contract manufacturers have become an integral part of the overall biopharmaceutical market. This trend is also gaining popularity within the antibody manufacturing market, as developers are increasingly outsourcing their antibody manufacturing requirements to contract service providers. This can be attributed to the fact that employing such third-party service providers offers various advantages,

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July 28, 2020

Wearable Injectors: Simplifying Chronic Disease Management

By Ishita Nanda Injectors, Injectors Market  1 Comment

The last few years have witnessed a rising incidence of chronic illnesses across the globe. Long term clinical conditions, such as neurological disorders, cardiovascular disorders, chronic pain and oncological disorders, have been shown to impose a significant burden on the modern healthcare system and those who suffer from such diseases. It is reported that about

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July 27, 2020

Human Microbiome: Significant Potential of Gut Flora

By Nancy Kapila Human Microbiome  1 Comment

Human Microbiome Therapies are Viable Alternatives to Antibiotics, with Substantial Therapeutic Potential The term microorganisms was perceived to be synonymous to harmful, disease causing agents, until the discovery of certain beneficial microbial colonies in the human system. Currently, humans and a variety of species of bacteria, yeast and protozoa, are known to co-exist in mutually

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July 23, 2020

Wearable Injector Market: The Evolving Trends

By Ishita Nanda Injectors, Injectors Market  1 Comment

The field of on body injector devices has witnessed a lot of innovation in the recent years. Specifically, large volume wearable injector is certainly a boon due to their ability to address challenges associated with the administration of high volume formulations, viscous drug solutions and cater to frequent dosing requirements of patients suffering from chronic

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July 22, 2020

Gut Microbiome: Fighter Against COVID-19

By Nancy Kapila Covid19, Healthy Microbiome  1 Comment

The COVID-19 pandemic is spreading to every corner of the world. During this worldwide attack of virus, human beings are highly concerned for their immune system, since it is the only savior currently. In circumventing a response to pathogenic infections like coronavirus, a healthy gut microbiome is essential to maintain an optimal immune system in

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July 22, 2020

Drug Repurposing Industry to Boom due to the Pandemic

By Jasmeet Bhalla Drug Repurposing  1 Comment

Since, the outbreak of novel coronavirus, drug repurposing industry has become one of the core research strategies for finding a treatment. Several clinical studies for the already approved repurposed drugs, have been registered in order to identify cure for the novel coronavirus infection. It is known that on an average, it takes around 12 to

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July 17, 2020

Medical Device CRO – The next Growth Opportunity

By Simriti Gupta Medical Device  1 Comment

Over the past decade, numerous scientific and technological breakthroughs in the medical device CRO industry have resulted in an accelerated pace of research and innovation within this domain. Further, the demand for high quality and efficient medical devices, driven by a growing geriatric population and increasing incidence of various chronic clinical conditions, is on the

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July 9, 2020

Fill Finish Services: Impact of the Growing Biopharma Pipelines

By Gaurav Chaudhary Biopharmaceutical, Biotech  1 Comment

Biopharmaceuticals represent the most rapidly growing and high-value segment of the pharmaceutical industry. Growing at an annualized rate of ~10%, the biologics contract manufacturing market stands tall with more than 5,000 biologics in development and over 300 FDA approved biologics, since 2002. Biologic drug development is characterized by high quality standards and a rapidly growing

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July 8, 2020

ADME Testing Services: Rising Opportunities for Service Providers

By Gaurav Chaudhary Market Research, Testing Services  0 Comments

According to the US Food and Drug Administration (USFDA), less than 10% of investigational new drug (IND) candidates progress beyond the submission of a new drug application (NDA); this implies that majority of the drug / therapy candidates fail to reach the market owing to unacceptable safety and efficacy profiles and the problems associated with

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July 8, 2020

Autoinjectors: Increasing Demand for Self-Administration Devices

By Gaurav Chaudhary Autoinjectors, Drug Adherence, Medical Device, Medical Devices and Technology, Therapeutics  0 Comments

Over the last decade, autoinjectors have emerged as a promising therapeutic commodity for safe administration of parenteral therapies. Patients who suffer from chronic diseases, such as diabetes, rheumatoid arthritis and multiple sclerosis, often require frequent dosing of medication which poses significant inconvenience to them for visiting proper healthcare centers. Hence, autoinjector devices enable such patients

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July 3, 2020

Peptide Therapeutics – A Deeper Look Into the CMO Market

By Simriti Gupta Contract Manufacturing, Manufacturing  1 Comment

The recent years have portrayed the renaissance of peptide therapeutics, as pharma industry has once again turned its attention towards the potential of therapeutic peptides. Adoption of peptide therapeutics agents have side-lined some of the earlier concerns associated with them, such as drug bioavailability enhancement, and has led to manufacturing of high-quality peptide therapeutics in

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July 3, 2020

In Vitro ADME Testing Services for Outsourcing Requirements

By Gaurav Chaudhary ADME Testing, Drug Discovery  1 Comment

It is important to note that the process of drug discovery is extremely demanding, both in terms of capital and time. In fact, the overall amount spent on R&D initiatives in the pharmaceutical / biotechnology sector has increased from around USD 128 billion in 2008 to USD 165 billion in 2018. Moreover, only a small

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June 25, 2020

TPD: A Major Therapeutic Modality in the Coming Decade

By Gaurav Chaudhary Protein Degradation, Therapeutics  1 Comment

The targeted protein degradation (TPD) approach is believed to possess the potential to unlock the undruggable proteome profile, which was traditionally considered to be inaccessible. Compared to conventional inhibition strategies, TPD offers several benefits, which include the opportunity to completely remove aberrant proteins and associated systemic malfunctions. As a result, TPD-based therapeutics have generated enthusiasm

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June 25, 2020

PARP Inhibitors for Treatment of Advanced Cancer Indications

By Gaurav Chaudhary Cancer, cancer therapeutics  1 Comment

Cancer is considered to be the second leading cause of mortality, after cardiovascular diseases, accounting for every sixth reported death in the world. The International Agency for Research on Cancer (IARC) states that the number of new cancer cases is expected to grow to 27.5 million across the globe, by 2040. Experimental evidence has shown

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June 23, 2020

Cell Therapy Manufacturing: A Potential Answer for COVID-19?

By Simriti Gupta Cell Therapy, COVID-19  1 Comment

With the success of first vaccine to reach phase I clinical trial and turning out to be safe, well-tolerated, and capable of generating an immune response against the virus in humans, a lot of hope has been created with these coronavirus preventive vaccines. However, the research is still ongoing to develop novel therapeutic treatments that

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June 23, 2020

Targeted Protein Degradation – A New Frontier in Modern Medicine

By Gaurav Chaudhary Drug Discovery, Protein Degradation  1 Comment

The concept of targeted protein degradation (TPD) presents revolutionary drug development opportunities and is anticipated to bring about a paradigm shift in modern healthcare. While conventional medicines, such as small molecule inhibitors and monoclonal antibodies, address fewer than 20% of the proteome, targeted protein degradation offers a unique means to tap into the rest of

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June 22, 2020

Computer Aided Drug Discovery Providers for Large Molecules

By Nancy Kapila Drug Discovery  1 Comment

Over time, the complexities associated with drug discovery have increased, especially in case of large molecule drugs, which are inherently more complex than conventional small molecules. As a result, an increase in the overall research and development (R&D) expenditure in the pharmaceutical contract manufacturing / biotechnology sector has been witnessed. In addition to the complexities

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June 22, 2020

In Silico Drug Discovery: Drug Discovery Operations in COVID-19

By Gaurav Chaudhary COVID-19, Drug Discovery  1 Comment

The COVID-19 pandemic is predicted to throw the global economy into recession, with loss of trillions of dollars. The pharmaceutical industry cannot escape the brunt of the circumstances as well. In fact, according to a survey, 95% of healthcare industry professionals are worried about the impact the pandemic is likely to have on the industry. So far,

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June 18, 2020

Liquid Biopsy: The Beginning of a New Era in Cancer Diagnostics

By Ishita Nanda Cancer, Liquid Biopsy  1 Comment

Cancer is known to be one of the leading causes of death worldwide. In 2019, 0.6 million deaths due to cancer are estimated in the US alone.  Moreover, the World Health Organization has estimated the number of new cancer cases to rise by 70% over the next 20 years. One of the primary reasons for

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June 18, 2020

Immune Checkpoint Inhibitors: Another Big Opportunity

By Ishita Nanda cancer therapeutics, Therapeutics  1 Comment

There is an urgent unmet need for developing innovative and effective cancer therapeutics for the treatment of patients with late-stage and refractory cancer. Amidst the widespread initiatives to develop more targeted anti-cancer therapies, immune checkpoint inhibitors emerged as a highly specific and potent option to eradicate tumor cells with minimal side effects. Once the body

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June 17, 2020

Ophthalmic Drugs Contract Manufacturing Industry

By Abhishek Dogra Contract Manufacturing, Manufacturing, Ophthalmic Drugs  1 Comment

In the past two decades, advances in optometry, along with an increased understanding of human eye and vision care, have led scientists to develop innovative treatment methods in order to treat eye disorders and to overcome the limitations offered by conventional medical practices. The current ophthalmic diseases treatment landscape is characterized by a number of

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June 17, 2020

Ophthalmic Medication: Outsourcing has become a popular trend

By Gaurav Chaudhary Contract Manufacturing, Ophthalmic Drugs  1 Comment

Owing to various reasons, such as growing manufacturing demand, need for specialized facilities, equipment and operational expertise, and high costs of development associated with certain drugs / therapies, a number of innovator companies have demonstrated a preference to outsource certain aspects of ophthalmic medication development and production operations to contract service providers. Over 240 companies

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June 17, 2020

Microbiome Manufacturing: Opportunities for Specialized CDMOs

By Gaurav Chaudhary Contract Manufacturing, Microbiome Research  1 Comment

What is the current development pipeline of microbiome manufacturing based live biotherapeutics? With over 85 products under preclinical and clinical development, the current development pipeline of microbiome manufacturing based live biotherapeutics has several promising candidates, which are anticipated to get commercialized over the next few years. Hence, the demand for R&D and manufacturing services for

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June 11, 2020

ANTIBODY DRUG CONJUGATES: THE RECENT APPROVALS

By Ankita Kashyap Antibody Drug, Healthcare, Pharmaceuticals  1 Comment

Antibody-Drug Conjugates (ADCs) have captured the attention of both large and small pharmaceutical companies, and academic / research institutions, engaged in the ADC contract manufacturing market. For the past few years, several failures of clinical trials were blamed for the lack of interest of some companies in this therapeutic approach. However, after a decade-long dribble

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June 11, 2020

Needle Free Injection System: Simplifying COVID-19 Treatment

By Ishita Nanda Coronavirus, COVID-19, Medical Device, Medical Devices and Technology  1 Comment

The apocalyptic images of the COVID-19 induced locked-down world are heart wrenching. All healthcare related domains are being created at a rapid rate. Around the world, the coronavirus pandemic is overstretching health services and reportedly more than 40 companies have boosted their R&D efforts to hit the bulls eye and deliver the much awaited coronavirus

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June 8, 2020

CRISPR Gene Editing: A Solution to Address COVID-19

By Gaurav Chaudhary Coronavirus, COVID-19, Diagnostics  1 Comment

As we know, COVID-19 is causing large scale loss of life and severe human suffering. With the pandemic spreading across the globe, researchers are racing against the clock to develop diagnostic tools, coronavirus preventive vaccines and treatments. Recently, WHO has launched a Solidarity clinical trial to assess relative effectiveness of four potential drugs against COVID-19.

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June 4, 2020

ASCO 2020: AstraZeneca Presents a Game-Changer in Lung Cancer

By Gaurav Chaudhary Cancer  1 Comment

While the AstraZeneca at ASCO 2020 presentation was virtual this year, the phase III results from AstraZeneca’s drug Tagrisso, in lung cancer patients, were as real as they could get. 89% of patients treated with Tagrisso were alive and cancer-free after two years, compared to 53% of patients treated with the placebo. Oncology Dominance AstraZeneca

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June 2, 2020

Microbiome Therapeutics Fuel the Manufacturing Demand

By Gaurav Chaudhary Biotherapeutics, Manufacturing, Microbiome Research  1 Comment

Microbiome therapeutics are fragile bacteria, which require ideal conditions of heat, moisture and pH of products, to survive and prevent premature germination. In fact, microbiome manufacturing is presently one of the biggest bottlenecks in this domain; manufacturing such products is both technically challenging and financially demanding. One of the biggest challenges in the development of

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May 26, 2020

Oligonucleotide Drugs Pipeline Escalates Manufacturing Demand

By Gaurav Chaudhary COVID-19, Oligonucleotides  2 Comments

As therapeutic agents, oligonucleotide drugs are known to be associated with several unique features, such as high selectivity and potency (similar to biologics), and differentiated pharmacology, which further augment their drug-like properties. At present, eight oligonucleotide drugs are available in the market, namely (in reverse chronological order of year of approval) GIVLAARI™ (2019), ONPATTRO® (2018),

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May 25, 2020

Oligonucleotides: A Response to COVID-19 Pandemic

By Gaurav Chaudhary COVID-19, Covid19, Oligonucleotides  1 Comment

Never before, scientists say, the universal community of researchers have put a halt to all other ongoing research and have urgently focused towards swiftly evolving health emergency. In the past few months, scientists have been repurposing their research efforts towards oligonucleotides contributing to the global effort in response to developing coronavirus preventive vaccines. For the

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May 20, 2020

Biopharma Contract Manufacturing Market in China: Covid-19 Impact

By Simriti Gupta Biopharmaceutical, Contract Manufacturing, COVID-19  1 Comment

China, epicenter of the COVID-19, is the world’s second largest pharmaceutical market and accounts for 20 % of the global output of APIs. With over 25 biologics and biosimilar products approved till date and close to 1,000 clinical trials, investigating a variety of biologics and biosimilars, being underway in this region, the biopharma contract manufacturing

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May 19, 2020

Neoantigen Targeted Therapies: Personalized Anti-cancer Therapy

By Ishita Nanda Anti-cancer, Anti-cancer Therapy, Therapies  1 Comment

Neoantigen Targeted Therapies Pave the Way to Personalized Anti-cancer Therapy There is an urgent unmet need for developing innovative and effective cancer therapeutics for the treatment of patients with late-stage and refractory cancer. Amidst the widespread initiatives to develop more targeted anti-cancer therapies, immunotherapy emerged as a highly specific and potent option to eradicate tumor

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May 15, 2020

Neoantigen Vaccines – A Weapon in the Fight against Cancer

By Ishita Nanda Cancer, Therapies  1 Comment

Cancer – one of the most feared and dreaded diseases. It is known to be one of the leading causes of death worldwide, accounting for 0.6 million deaths in 2018, in the US alone. The World Health Organization has estimated the number of new cancer cases, reported across the globe, to rise by 70% over

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May 7, 2020

Collaborative Robots: The Future of Manufacturing

By Nancy Kapila Cobots, Robots  1 Comment

The world has experienced a radical change with the advancements in technologies and systems that aid daily activities. Particularly, lab automation has played an important role in increasing the productivity and quality of the production process in various industries. Within the automation industry, robots have already been established; however, one of the fastest-growing segment of

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May 4, 2020

Collaborative Robotics Helping in Pandemic Management?

By Nancy Kapila Cobots, Coronavirus, COVID-19, Robots  1 Comment

With the new threat to humanity presented by Pandemic COVID-19, another bigger challenges for the pharmaceutical industries are bulk vaccine production in the limited time span. How will the pharma sector be going to cope with these challenges? Well, lab automation has always improved the quality and efficiency of the production process in the pharmaceutical

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April 24, 2020

Prefilled Syringe: Impact on COVID 19 and Vaccines

By Gaurav Chaudhary Coronavirus, COVID-19, Medical Device, Vaccines  1 Comment

Coronavirus(COVID 19) is spreading around the world, with 2.6 million global active cases. Till date, there are no approved treatments for COVID-19. However, multiple pharmaceutical companies are doing research at breakneck speed to develop therapeutics and coronavirus preventive vaccines against this novel virus. The pharma industry is hoping to compress the development timelines to get

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April 6, 2020

COVID-19: Drugwatch – 6 April 2020

By Snehasish Das COVID-19  1 Comment

To date, there are no approved treatments for COVID-19. However, the pharmaceutical industry is abuzz with activity as medical researchers strive to develop a cure, and possibly a vaccine, for the illness caused by the novel coronavirus. In this article, we have attempted to explore some of the more popular treatments / preventive measures that

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April 6, 2020

Covid Vaccines: Is the World Ready to Embrace the New Normal?

By Gaurav Chaudhary COVID-19  1 Comment

It is the first time in the history of medicine that so many scientists / researchers across the globe focused so urgently on a single disease in such a short span of time. Looking at the developments in the past few month, I really feel that COVID-19 vaccines has changed how the world does science

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April 6, 2020

Stem Cell Therapy: Hope to End Global Pandemic of COVID-19

By Ronit Sharma Coronavirus, Stem Cell Therapy  0 Comments

I would never have thought that a mutant flu virus could create that big panic in people at each and every corner of the world. In fact, the past few days in quarantine have really made me realize where exactly the humanity is heading. For majority of us, our lives are on a temporary hold

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April 5, 2020

COVID-19: Where are we today?

By Snehasish Das Infectious Diseases  4 Comments

Comparison with other communicable diseases According to worldometers.info, as of 5 April 2020 (5:30 PM GMT), the total number of COVID-19 cases rose to over a million, with a reported mortality rate of 5%. Further, a comparison with certain other communicable disease-related deaths (Figure below) presents a worrisome situation. As of 5-April 2020, the novel

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April 2, 2020

Fragment based Drug Discovery – Potential Drug Against Covid-19

By Ishita Nanda Drug Discovery  0 Comments

With over 855,000 cases and 42,000 deaths, the novel coronavirus has taken its toll on humanity. The pandemic is predicted to throw the global economy into recession, with loss of trillions of dollars. The pharmaceutical contract manufacturing industry cannot escape the brunt of the circumstances as well. In fact, according to a survey, 95% of

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April 2, 2020

Stem Cell Companies Contract Services Demand to Surge Rapidly

By Ishita Nanda Coronavirus, Stem Cells  1 Comment

As is the case with numerous pharmaceutical companies who have been racing to find a potential cure for the patients suffering from infection with Corornavirus, the stem cell companies have been on an outlook to identify novel stem cell therapy which can treat the disease and / or its symptoms. Athersys is developing a possible

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April 1, 2020

NHS Advises COVID-19 Related Risk Assessment of Phase I Trials

By Gaurav Chaudhary Clinical Trials  1 Comment

In a recently released statement, the NHS has advised all companies that are conducting early phase clinical trials to seek confirmation that the trials have undergone a risk assessment in relation to coronavirus (COVID-19). As per the statement, this is likely to result in the halt/termination of some of the virtual clinical trial. With several

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March 29, 2020

Cell and Gene Therapy Manufacturing: COVID-19 Impact

By Gaurav Chaudhary Cell Therapy, Gene Therapy, Vector Manufacturing  1 Comment

With close to half-million infections and the economy showing signs of the 2008 financial crisis, COVID-19 has impacted several industries. Government institutes and industry players have announced various steps to deal with the ongoing situation. In this article, we will highlight the developments in the cell and gene therapy manufacturing industry amid the ongoing COVID-19

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March 29, 2020

Continuous Manufacturing: Solution to Pharma Manufacturing

By Gaurav Chaudhary Contract Manufacturing, Pharmaceuticals  1 Comment

The ongoing COVID-19 crisis has put the pharmaceutical manufacturing supply chain under close scrutiny. The overdependence of the US on China and India to meet its API demand has been the talk of the town. However, with the number of infected cases in the US surpassing that of China, the focus has shifted from discussing

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March 29, 2020

Gene Therapy Companies: Impact on COVID-19

By Gaurav Chaudhary Gene Therapy  2 Comments

In a recent press release, bluebird bio, one of the leading gene therapy companies, announced that COVID-19 has delayed the EU launch and US filing of the company’s gene therapy candidate Zynteglo (LentiGlobin). The company now expects to dose the first commercial patient with Zynteglo in Germany in the second half of 2020. Earlier, the company had

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March 29, 2020

COVID19 Vaccine: Do We Have Enough Manufacturing Capacity?

By Gaurav Chaudhary Vaccines  2 Comments

As per a recent article published in Financial Times, Sanofi has warned that Europe lacks the coronavirus preventive vaccines market capacity to cope with the pandemic. Roots Analysis, in a recent report, has identified more than 40 covid19 vaccine that the currently being developed against the virus. To know more about the covid vaccines under

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March 29, 2020

Virtual Clinical Trials During COVID-19

By Gaurav Chaudhary Clinical Trials  2 Comments

The ongoing COVID-19 pandemic has been nothing short of a nightmare. As the number of infected patients approaches 400,000, there is already a sense of worry looming across the industries. From disrupted supply chains to a prominent decrease in demand, the pharmaceutical industry is also facing its share of difficulties. A prominent shift towards the

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March 24, 2020

Endocannabinoid System and Clinical Trials

By Ishita Nanda Clinical Trials, Pharmaceuticals  3 Comments

To err is human, to rectify divine, this irony perhaps holds truer for cannabis than any other domain. After using cannabis in multiple forms for at least 10,000 years, a series of events, including spread of misinformation, anti-Mexican sentiment and fear led to the ban of nature a.k.a. cannabis. The US implemented Marijuana Tax Act

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March 16, 2020

Biomarkers in Cancer: Benchmarking Big Pharma Activity

By Gaurav Chaudhary Diagnostics, Oncology  1 Comment

Over the past few years, therapeutic advancements in conventional treatment paradigms have led to an increase in survival among cancer patients. Recent developments in the field of immuno-oncology, such as the introduction of several liquid biopsy techniques, adoptive T-cell therapies, and immune checkpoint inhibitor based therapies, have demonstrated significant potential, and some of the aforementioned

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March 15, 2020

Cell Therapy Manufacturing: Here are the Key Innovations

By Gaurav Chaudhary Cell Therapies, Cell Therapy, Gene Therapy  2 Comments

Last week, during our weekly industry update sessions, our prime focus was to understand the recent innovations in the field of cell therapy manufacturing. We were also looking out for players that are driving these innovations. To start with, the first news that caught our attention was Novartis’ decision to sidestep Europe travel ban to

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March 13, 2020

Targeted Protein Degradation: Nurix betters Kymera

By Gaurav Chaudhary Pharmaceuticals  1 Comment

It is not very common to hear venture capital firms back competitors in the same week. It happened yesterday with Nurix announcing a USD 120 million backing yesterday, immediately after Kymera had grabbed an almost similar amount earlier this week. This does tell us something about the field of Targeted Protein Degradation! Read on. How

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March 12, 2020

TPD and the Rise of Kymera Therapeutics

By Gaurav Chaudhary Pharmaceuticals  1 Comment

Targeted protein degradation (TPD), as a mechanism to target previously untreatable conditions, was one of the key highlights of the year 2019. In an article published late last year titled targeted protein degradation market, we discussed, in detail, the epic rise in the popularity of TPD. What is TPD? TPD is an emerging modality that

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March 12, 2020

Microbiome CMO: Time to Push the Increase Capacity Button

By Gaurav Chaudhary Contract Manufacturing, Microbiology  1 Comment

The interest in the trillions of human microbiome present in the human body has attracted a lot of research effort in the microbiome domain. The first such effort at a large scale was The Human Microbiome Project, conducted by the National Institutes of Health in the United States, which characterized the microbial communities at five

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March 11, 2020

Cell Therapy and The Rise of Novel Technologies

By Gaurav Chaudhary Cell Therapies, Cell Therapy, Contract Manufacturing, Gene Therapy, Natural Killer Cells  2 Comments

Roots Analysis has actively tracked the developments in the field of cell therapy and gene therapies. The team has focused on identifying the key challenges that are hampering the growth of these revolutionary therapies. To identify the challenges, the team has interviewed several stakeholders involved in cell therapy development and manufacturing. In addition, a recent

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March 9, 2020

Coronavirus: The World Must Unite In Its Fight

By Gaurav Chaudhary Biologics, Vaccines  1 Comment

A lot has happened. And that too in a short span of time. A few weeks ago, everyone outside China was worried about the quarantined cruise ships. No one at that stage would have thought that, just in a few days, the virus may be knocking at the doorsteps. Now there is fear and it

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March 6, 2020

ADC: The Excitement Continues to Build

By Gaurav Chaudhary Biologics, Drug Discovery  1 Comment

So, another round of the World ADC (Antibody Drug Conjugates) just concluded. With a stellar line up that included Alain Beck from Pierre Fabre, Thorsten Sperber from Immunomedics, Nicholas Choong form Seattle Genetics, Rakesh Dixit from BioNavigen, Trevor Hallam from Sutro Bio and many other eminent personalities, the event did live up to its expectations.

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February 14, 2020

Blockchain in Genomic Data Management

By Gaurav Chaudhary Diagnostics, Drug Discovery, Genomics  2 Comments

Have you had your genomics sequenced? If you asked this question a few years ago, people would have thought you were crazy. However, today, genetic tests are up for sale in supermarkets! Fifteen years ago, the first ever Human Genome Project was carried out, which took more than 13 years to complete. This (Human Genome

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February 4, 2020

Catalent’s Shopping List: Towards a One-Stop Cell & Gene Therapy CMO

By Gaurav Chaudhary Cell Therapy, Gene Therapy  3 Comments

There appear to be no Monday blues for Catalents as the company announces the acquisition of MaSTherCell Global, a technology-focused cell and gene therapy contract development and manufacturing organization. Following its last year’s acquisition of Paragon Bioservices (a leading viral vector developer), Recent acquisition by Catalent in Gene Therapy segment has extended the company’s leadership

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January 3, 2020

Cell and Gene Therapy Manufacturing: Rising Demand Forces Companies to Look Beyond Viral Vectors

By Gaurav Chaudhary Cell Therapies  2 Comments

The rise in the popularity of cell and Gene Therapy has been widely talked about in recent years. The rise in this popularity has come with its own challenges, a number of which were identified in a recent report by Root Analysis. The challenges vary from the high cost of manufacturing to low capacity. In

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January 2, 2020

Vector Manufacturing Market: Opinion Leaders Highlight Key Concerns

By Gaurav Chaudhary Vector Manufacturing  3 Comments

The growing pipeline of cell and gene therapies has led to an increase in demand for high-quality gene delivery vehicles and, therefore, has created significant opportunities for companies with expertise in manufacturing viral and non-viral vectors. In an article published last year, I discussed the growing cell and gene therapy market and how it has

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January 1, 2020

CMO, CMO Everywhere, Not a Single One That Fits: The Reality of Biopharma Contract Manufacturing Market

By Gaurav Chaudhary Biopharmaceutical  2 Comments

I was recently involved in a discussion with the global outsourcing manager of one of the big pharma companies. The premise of the discussion was around the criteria that big Biopharma Contract players follow for choosing a supplier for their products. One key question that came up in the discussion was whether one-stop-shops are really

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January 1, 2020

A Pizza Hut Prescription for Gene Therapy Companies

By Gaurav Chaudhary Gene Therapy  2 Comments

As we enter 2020, one drug class that is set to take-off is gene therapy. With three approvals (Zolgensma® (US), Zynteglo™ (Europe) and Beperminogene Perplasmid (Japan), 2019 was a break out year for gene therapy developers. The $16 billion-plus investment by various investors finally seems to be paying off as we enter 2020 with a

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December 28, 2019

Targeted Protein Degradation: Growth Drivers and Roadblocks

By Gaurav Chaudhary Degradation Market  2 Comments

In a recent article, I discussed the rise of targeted protein degradation (TPD) therapeutics and the surge in big pharma interest in this emerging space. With more than 3,600 tweets posted over the last three years to over 5,000 articles published over the last decade, the concept of targeted protein degradation has got the right

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December 27, 2019

DNA Encoded Library: Big Pharma Interest Rises

By Gaurav Chaudhary DNA Encoded  3 Comments

When a big pharma agrees to spend millions in acquiring a drug discovery company, the world is bound to take note. The same happened earlier this year – the acquisition of Nuevolution AB for 1.61 billion Swedish crowns ($166.8 million) was a piece of big news in the drug discovery world, validating the potential of DNA

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November 12, 2019

Evolution of Cancer Diagnostics: Rise of Novel Non-Invasive Methods

By Gaurav Chaudhary Cancer  0 Comments

Cancer diagnosis, today, employs a mix of invasive and non-invasive strategies. Invasive cancer diagnostic methods are generally expensive and uncomfortable. Biopsies have been the gold standard to determine the clinicopathological characteristics of cancer tissues for many years. The procedure is very uncomfortable and painful for patients and in many cases, the results are known to

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November 12, 2019

CAR T Cell Therapy: Autolus Presents Data on AUT06NG

By Gaurav Chaudhary Cell Therapies  0 Comments

Autolus Therapeutics, a clinical-stage biologics contract manufacturing company developing next-generation programmed T cell therapies for the treatment of cancer, presented pre-clinical data on AUTO6NG, the company’s next-generation GD2-targeting CAR T cell therapy, at the 34th Annual Meeting of the Society for Immunotherapy of Cancer (SITC). What did the results highlight: The results demonstrated the utility of

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November 11, 2019

Microbiome: New Study Uncovers Role of Bacteria in Bowel Cancer

By Gaurav Chaudhary Microbiome Research  0 Comments

Dr. Kaitlin, from the University of Bristol, speaking at the 2019 NCRI Cancer Conference, confirmed that they have discovered evidence of the presence of an unclassified type of bacteria from the bacterial group named ‘Bacteroidales’ increased the chances of bowel cancer by 2 to 15 percent.  The researchers employed the technique known as Mendelian randomization to

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November 11, 2019

New Research in ALS – Mitoautophagy Responsible for Development of Early Stages of Neurodegeneration

By Gaurav Chaudhary Neurodegeneration  0 Comments

Researchers at Northwestern Medicine have discovered a new phenomenon in the brain that could explain the development of early stages of neurodegeneration seen in diseases such as ALS, which affects voluntary muscle movement such as walking and talking Mitoautophagy. What is the discovery: The researchers have invented a new term to describe the discovery: Mitoautophagy,

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November 9, 2019

FDA Approves Celgene’s REBLOZYL® for the Treatment of Anemia

By Gaurav Chaudhary Celgene's REBLOZYL  0 Comments

The U.S. Food and Drug Administration FDA approves Celgene’s REBLOZYL® (luspatercept-aamt) for the treatment of anemia in adult patients with beta-thalassemia who require regular red blood cell (RBC) transfusions. What is Beta-thalassemia:  Beta-thalassemia is a blood disorder that reduces the body’s production of hemoglobin. Low levels of hemoglobin lead to a shortage of mature red blood cells and a lack of oxygen in

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November 9, 2019

CAR-T Pipeline Update: Celgene posts pivotal data ahead of FDA filing

By Gaurav Chaudhary Cell Therapies, Cell Therapy  0 Comments

Celgene has recently published positive data from a pivotal trial (NCT02631044) of its CAR-T therapy. As per the reports, the data look competitive against Gilead’s Yescarta and Novartis’ Kymriah, leading analysts to predict Celgene will win FDA approval next year. This is a big news for the overall CAR-T pipeline. As per the reported data, the

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November 8, 2019

New Real-World Data Unveiled at ACAAI Indicates Comparable Clinical Practice Logistics to Implement Oral Immunotherapy and Environmental Allergy Shots

By Gaurav Chaudhary Clinical Practice  0 Comments

In a recent press release by Aimmune Therapeutics, the company reported that the Clinical Practice logistical needs for implementing oral immunotherapy (OIT) for food allergies, such as peanut allergy, into clinical practice are comparable to those for subcutaneous immunotherapy (SCIT) for environmental allergies. These data were presented at the American College of Asthma, Allergy and Immunology

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November 8, 2019

CRISPR-edited Immune Cells Prove Safe in Small Cancer Study

By Gaurav Chaudhary Genomics  0 Comments

At the American Society of Hematology (ASH) annual meeting in Orlando, the team, led by the Abramson Cancer Center of the University of Pennsylvania, will discuss two multiple myeloma patients and one sarcoma patient who is participating in a trial, which is also supported by Tmunity Therapeutics (a company that recently raised $75 million in

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November 8, 2019

Party Like Celebrities: American Gene Technologies Hosts a Red Carpet Event to Celebrate IND Submission

By Gaurav Chaudhary Gene Technologies  0 Comments

On November 6, 2018, American Gene Technologies (AGT) announced that it will host a red carpet event to celebrate a significant milestone in the company’s 11-year history of scientific research in cell and gene therapy. Last month, the company successfully submitted its Investigational New Drug (IND) application to the Food & Drug Administration (FDA) to

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November 8, 2019

T-Cell Therapies Funding Update: Tmunity Raises $75 Million in Series B Funding

By Gaurav Chaudhary T-Cell Therapies  0 Comments

On 31st October 2019, Tmunity Therapeutics, a private biotherapeutics company focused on saving and improving lives by delivering the full potential of next-generation T-cell Therapies, announced the closing of $75 million Series B financing. Who were the key investors in T-cell Therapies: The financing was led by Andreessen Horowitz (also known as “a16z”). Joining the

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November 8, 2019

Avantgen Enters a Strategic Collaboration Agreement for its NK Cell Engager Technology

By Gaurav Chaudhary Natural Killer Cells  0 Comments

On 7 November 2019, AvantGen, a biotechnology company with its array of technology platforms for antibody discovery, optimization, and novel NK cell engager generation, announced a strategic agreement with an undisclosed biopharmaceutical company for the purpose of generating multiple novel bi-specific NK cell engaging therapeutic antibody product candidates. Under the terms of the agreement, AvantGen

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November 3, 2019

61% of the Genome Editing Service Providers are based in North America

By Gaurav Chaudhary Genome Editing  0 Comments

The rising demand for genome editing services has resulted in the rise of several players in the last few years. Around 61% of the companies that offer these services are based in North America. To get more free insights about the genome editing services market, check out the report Genome Editing Services market report.

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November 3, 2019

Cell Line Engineering is the Most Common Service Offered by CRISPR-Based Genome Editing Companies

By Gaurav Chaudhary Uncategorized  0 Comments

As per a recent market report by Roots Analysis, cell line engineering is the most popular service, provided by close to 31% of the CRISPR based genome editing service providers. To get additional free insights about the genome editing services market, check out the report Genome Editing Services Market Report.

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November 3, 2019

Genome Editing Services Market Snapshot

By Gaurav Chaudhary Genomics  0 Comments

The rising demand for genome editing services has resulted in the rise of several players with a wide range of capabilities. Currently, there are close to 80 players that claim to offer CRISPR based genome editing services. To get more insights about the market, check out the detailed report market report – Genome Editing Services.

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November 3, 2019

Medical Device Contract Manufacturing Market Size

By Gaurav Chaudhary Medical Device  0 Comments

More than 100 medical devices were approved by the FDA in 2018, while several are currently being evaluated across more than 9,500 (active) clinical trials, worldwide. Further, the increase in the aging population, coupled with a rise in the prevalence of chronic disorders, are likely to drive the demand for medical devices. Therefore, in order

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November 3, 2019

Experts Highlight Unmet Needs in T-Cell Therapies Market

By Gaurav Chaudhary T-Cell Therapies  0 Comments

The CAR-T therapies market is projected to reach USD 11 Billion by 2030, growing at an annualized rate of 31%. Check out more insights about the overall T-cell therapies market, market report T-cell.

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November 3, 2019

More than 50 Large Volume Wearable Injectors are Available / Under Development

By Gaurav Chaudhary Autoinjectors  0 Comments

Over time, both drug developers and medical device Injectors manufacturers, have entered into strategic alliances to combine their respective expertise and develop appropriate drug-device combination products. Presently, multiple such combinations, facilitating easy delivery of both insulin and non-insulin drugs, in large volumes, are either already available in the market or under development. Check out more

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November 3, 2019

Auristatin Emerged as Most Popular ADC Payload

By Gaurav Chaudhary Clinical Pipeline  0 Comments

Antibody drug conjugates are a promising class of therapeutic drugs accepted worldwide for the treatment of cancer. ADCs comprise monoclonal antibodies that are conjugated to the cytotoxic payload via linkers that are directed towards the targeted antigen expressed on the tumor cell surface—resulting in toxicity and initiating killing action. The Antibody drug conjugate market provides

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November 3, 2019

Antibody Drug Conjugates Pipeline

By Gaurav Chaudhary Antibody Drug  0 Comments

For more free insights, check out the detailed report ADC market insights report.

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November 3, 2019

Stem Cell Therapy Contract Manufacturing Market

By Gaurav Chaudhary Stem Cell Therapy  0 Comments

Check the detailed report here.

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November 2, 2019

ADCs Pipeline Update: Daiichi Sankyo Initiates Clinical Trial

By Gaurav Chaudhary ADCs Pipeline  0 Comments

On October 31, 2019, Daiichi Sankyo and Sarah Cannon Research Institute announced the dosing of the first patient in a first-in-human phase 1/2 study (NCT04145622) evaluating DS-7300. What is DS-7300? DS-7300 is an investigational B7-H3 targeting antibody-drug conjugate (ADC). What is B7-H3? It is a Type I transmembrane protein belonging to the B7 family, which includes immune

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November 1, 2019

Cancer Biomarkers and Rise of TMB

By Gaurav Chaudhary Diagnostics  0 Comments

Over the years, several cancer biomarkers have been identified, which can be used to predict response to certain types of immunotherapy drugs. However, due to the inherent complexity of the immune microenvironment and differences in the genomic makeup of individual patients, most of these biomarkers in cancer have been proven to be insufficient in predicting

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October 30, 2019

ADCs Pipeline Update: Femtogenix Presents Novel Data on ADCs Containing Reduced Potency Payloads

By Gaurav Chaudhary ADCs Pipeline  0 Comments

Femtogenix, a UK based biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analog from its Pyridinobenzodiazepine (PDD) ADC payload platform in solid tumor models. The presented data demonstrated that Femtogenix’s reduced potency payload has a favorable

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October 25, 2019

Cell Therapy Manufacturing: A Rising Opportunity for Stakeholders

By Gaurav Chaudhary Cell Therapy  0 Comments

The Compal Group’s Raypal Biomedical and Kaohsiung Medical University Chung-Ho Memorial Hospital on October 22 signed an MoU to jointly set up a GTP (good tissue practice) cell therapy manufacturing laboratory in Kaohsiung City, southern Taiwan. What are the key capabilities of Raypal in cell therapy manufacturing: Founded in 2016, Raypal specializes in R&D of

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October 25, 2019

Gene Therapy Pipeline Update: Orchard Therapeutics Presents Data on Metachromatic Leukodystrophy

By Gaurav Chaudhary Gene Therapy  0 Comments

Orchard Therapeutics, a commercial-stage biopharmaceutical company, announced initial results from a clinical trial (NCT03392987) with a cryopreserved formulation of OTL-200, gene therapy in development for the treatment of metachromatic leukodystrophy (MLD). Get the details of the results here. What is OTL-200 OTL-200 is autologous CD34+ cells transduced with a lentiviral vector containing human arylsulfatase A (ARSA) complementary

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October 25, 2019

Cell Therapy Market Update: MaxCyte Advances Phase I Clinical Trial of Lead mRNA-based Cell Therapy

By Gaurav Chaudhary Cell Therapy  1 Comment

MaxCyte, the global Cell Therapy, and life sciences company, announced the initiation of dosing in the third cohort of patients of MaxCyte’s Phase I clinical trial (NCT03608618) with the next higher cell dose of MCY-M11. The dose-escalation trial is evaluating the safety and tolerability, as well as preliminary efficacy, of MCY-M11 administered intraperitoneally across a series

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October 25, 2019

Gene Therapy Pipeline Update: Adverum Biotechnologies Doses First Patient for Wet AMD

By Gaurav Chaudhary Gene Therapy  1 Comment

Adverum Biotechnologies, a clinical-stage gene therapy company developing drugs to teated rare ocular diseases, announced that the first patient was dosed in the third cohort (n=9) of the ongoing OPTIC phase 1 clinical trial (NCT03748784) for ADVM-022 for the treatment of neovascular or wet age-related macular degeneration (wet AMD). What is ADVM-022? ADVM-022 utilizes a

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October 25, 2019

Gene Therapy Pipeline Update: AVROBIO Receives Orphan-Drug Designation

By Gaurav Chaudhary Gene Therapy  1 Comment

AVROBIO, a US-based company, developing lentiviral-based gene therapies, has announced that the U.S. Food and Drug Administration (FDA) has granted orphan-drug designation for the Company’s investigational gene therapy, AVR-RD-02, for the treatment of Gaucher disease. What is AVR-RD-02 AVR-RD-02 consists of the patient’s own hematopoietic stem cells, genetically modified to express glucocerebrosidase (GCase), the enzyme that is

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October 25, 2019

Cell Therapy Manufacturing Update: United Therapeutics Receives Permit

By Gaurav Chaudhary Cell Therapies, Cell Therapy, Contract Manufacturing, Stem Cells  0 Comments

As per recent news coverage, United Therapeutics has received a permit for $9.5 million build-out of its cell therapy facility on the second floor of Mayo Clinic’s Discovery and Innovation Building. What is the area of the facility:  The facility will have a total of 21,843-square-foot space. What are the capabilities at the facility:  The facility will house

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October 24, 2019

Gene Therapy Funding Update: With a Promise of $100 Million in Funding, US Government Bets Big on Gene Therapy

By Gaurav Chaudhary Gene Therapy  1 Comment

In a recent press announcement, The U.S. National Institutes of Health (NIH) has agreed to invest in the development of Gene Therapy in an attempt to cure HIV and sickle cell diseases. The program, for which NIH will partner with The Bill & Melinda Gates Foundation, will involve funding of $100 million each over the next

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October 24, 2019

Cell and Gene Therapy Technology Update: ReNeuron Presents Positive Data

By Gaurav Chaudhary Cell Therapies, Cell Therapy, Gene Therapy  1 Comment

ReNeuron, the UK based, clinical-stage stem cell therapeutics company, announced that new data relating to its CTX stem cell platform will be presented today at the 27th Annual Congress of the European Society of Gene and Cell Therapy (ESGCT). Dr. Steve Pells, Principal Investigator at ReNeuron, will present new data showing the phenotypic stability and scalability

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October 22, 2019

Gene Therapy Pipeline Update: Rocket Pharmaceuticals Receives IND Clearance for Gene Therapy for Pyruvate Kinase Deficiency

By Gaurav Chaudhary Gene Therapy  1 Comment

Rocket Pharmaceuticals, a New York-based, clinical-stage company, developing first-in-class gene therapies for rare and devastating inherited diseases announced clearance of Investigational New Drug (IND) by the FDA for RP-L301 gene therapy. RP-L301 is a lentiviral vector (LVV)-based gene therapy for the treatment of Pyruvate Kinase Deficiency (PKD), a genetic rare disease. Last month, the company received

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October 22, 2019

Gene Therapy Pipeline Update: Homology Medicines Presents Data Demonstrating Preclinical Proof-of-Concept

By Gaurav Chaudhary Gene Therapy  1 Comment

Homology Medicines, a company using proprietary gene editing and gene therapy platform announced the presentation of preclinical data supporting its investigational gene therapy programs for the treatment of metachromatic leukodystrophy (MLD) and phenylketonuria (PKU) at the American Society of Human Genetics (ASHG) 2019 Meeting. The presented preclinical data showed the results from studies conducted in

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October 22, 2019

Alzheimer’s Pipeline Update: Biogen Takes a U-Turn on Failed Drug; Approval in Sight

By Gaurav Chaudhary Alzheimer's Pipeline  1 Comment

In one of the most drastic shifts in fortune in the pharmaceutical industry, Biogen has decided to submit its previously failed Alzheimer’s drug for approval. According to the company, The Phase 3 EMERGE (NCT02484547) study met its primary endpoint showing a significant reduction in clinical decline, and Biogen believes that results from a subset of patients

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October 22, 2019

Cell Therapy Manufacturing Update: Merck Becomes the First to Introduce Acoustic Technology

By Gaurav Chaudhary Cell Therapy  1 Comment

With its acquisition of FloDesign Sonics earlier this month, Merck/MilliporeSigma has become the first company to introduce acoustic technology in cell therapy manufacturing. The acquisition of FloDesign Sonics is a strategic fit for Merck, strengthening its ability alongside to manufacture cell-based therapies for patients. What is Acoustic Cell Processing:  Acoustic cell processing is a disruptive technology that

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October 22, 2019

Plasmid DNA Manufacturing Market Update: Cytovance®Introduces Integrated Single-Use Platform

By Gaurav Chaudhary DNA Manufacturing  1 Comment

In the ongoing shift of biologics manufacturers to single-use systems, Cytovance®, a leading biopharmaceutical CDMO, announced the addition of an integrated single-use platform for the manufacturing of plasmid DNA (pDNA) at their facilities in Oklahoma City, OK. According to the company, two grades are available (Critical Reagent Grade™, CGMP-grade) in lot sizes from 1g to 50g,

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October 22, 2019

Gene Therapy Funding Update: Exegenesis Bio raises $10 Million led by K2 Venture Partners

By Gaurav Chaudhary Gene Therapy  0 Comments

The gene therapy company, Exegenesis Bio has become one of the recent players to receive funding in the therapy space. According to a media statement, the company has completed fundraising of over 70 million yuan ($10 million), led by K2 Venture Partners and joined by Kaitai Capital and Legend Star. The company was founded by

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October 22, 2019

Gene Therapy Market Update: Researchers Deliver a Cure for Epidermolysis Bullosa (EB)

By Gaurav Chaudhary Gene Therapy  1 Comment

In a recent news update, a team of Irish gene therapy researchers announced a breakthrough in the search for a cure for one of the worst strands of the incredibly painful skin disease, EB (epidermolysis bullosa). According to the researchers, the incredibly painful genetic condition, which affects approximately 300 people in Ireland, is caused by a

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October 21, 2019

Gene Therapy Market: A Strong Pipeline with $12 Billion Opportunity by 2030

By Gaurav Chaudhary Gene Therapy  1 Comment

From being a thing of science fiction to topping the priority list of every big pharma player, gene therapies have come a long way. With multiple approved products, the field of gene therapies has gained substantial momentum over the last couple of decades. The growing burden of genetic disorders and the rising evidence of gene

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October 21, 2019

Technological Evolution of ADC Conjugation Platforms

By Gaurav Chaudhary ADC Conjugation  1 Comment

Last week, I wrote an article on the key innovators in ADC therapeutics space, Technological highlighting the key winners at the 6th World ADC Awards. One of the winners, that has really impressed several drug developers in this space, is Zymeworks. The company has its proprietary conjugation Technological platform, ZymeLink™, which offers site-specificity and customization

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October 21, 2019

Gene Therapy Market: Big Pharma Bets Big

By Gaurav Chaudhary Gene Therapy  0 Comments

Last week, I came across an interesting article by Andrew Dunn titled Sanofi investing in gene therapy as R&D focus turns toward rare disease. The article caught my attention because in June, this year, Sanofi scaled back its four-year-old gene therapy alliance with Voyager Therapeutics, for the second time. If we just look at the news titles,

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October 18, 2019

ADC Therapeutics Market: 6th World ADC Awards Unfold Key Innovators

By Gaurav Chaudhary ADC Therapeutics  1 Comment

Last week, the eyes of all the key stakeholders in the Antibody Drug Conjugates (ADCs) Therapeutics space were on the developments happening in San Diego, California, at the 6th World ADC Awards.  The awards were meant to recognize the companies that are driving innovation in the field of ADCs Therapeutics. With six approved and marketed

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October 17, 2019

10 Key Facts About ADC Market

By Gaurav Chaudhary Antibody Drug  0 Comments

Global Antibody Drug Conjugates ADC market is expanding and is estimated to be around USD 7.72 billion in 2023. The compound annual growth rate of ADC market is estimated to be 9.50% in the coming decade. Roots Analysis has been publishing multiple articles and key insights pack for ADC market growing potential to keep the

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October 15, 2019

Gene Therapy Companies: 10 Key Facts

By Gaurav Chaudhary Gene Therapies  0 Comments

Gene therapy companies have emerged as the savior in offering sophisticated products to treat patients with defective genes and chronic diseases. There are two types of gene therapies on the basis of targeted gene location: germline gene therapy and somatic gene therapy. These therapies are implemented to treat several diseases, such as hemophilia, Parkinson’s, Alzheimer’s,

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October 14, 2019

T-Cell Immunotherapies Market: KOL Interviews Highlight Key Trends

By Gaurav Chaudhary T-Cell Immunotherapies  1 Comment

T-Cell immunotherapies have gained a lot of traction in recent years. With a plethora of clinical evidence and billions of dollars in investment, calling T-cell therapies as the next big thing might not be incorrect. As per the recent estimates, this space is likely to grow to USD 26 billion by 2030, at a CAGR

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October 14, 2019

Hunt for Novel Cancer Treatment Options and Rise of T-Cell Immunotherapies

By Gaurav Chaudhary Novel Cancer  1 Comment

Novel Cancer is known to be one of the leading causes of death worldwide, accounting for more than 600,000 deaths in 2018 in the US alone. As per the recent reports by, the World Health Organization (WHO), the number of new cancer cases globally is expected to rise by 70% in the coming 20 years. Despite

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October 12, 2019

Super Generics Market: The Untapped Gold Mine

By Gaurav Chaudhary Generics Market  0 Comments

The Super Generics industry has enjoyed a remarkable run over the past two decades. The vast healthcare cost-saving potential of these therapies has accelerated their adoption and proven the immense potential that generics have to reach wider patient segments. The super generic drugs market is estimated to be worth $38 billion in 2019 and is

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October 10, 2019

Synthetic Lethality: Rising Interest from Funding Agencies

By Gaurav Chaudhary Synthetic Lethality  0 Comments

After the immense success of PARP inhibitors at ESMO 2019, synthetic lethality has become the talk of the town. From industry analysts to healthcare researchers, everyone is now interested in this emerging space. In this article, we will look at the financial backing that this domain has received over the last few years and also

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October 10, 2019

Vector Manufacturing: Growing Cell and Gene Therapy Market

By Gaurav Chaudhary Cell Therapies, Cell Therapy, Contract Manufacturing, Gene Therapy  0 Comments

Cell and Gene Therapy CROs are the new entrants in the pharma Superstar Club. They are selling tickets faster than a Queen’s concert in the 1980s. In fact, as per the Alliance of Regenerative Medicine’s recent findings, there has been more than 75% year on year increment in funding to support the development of various cell and gene

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October 9, 2019

Synthetic Lethality Market: Riding on the ESMO 2019 Success of PARP Inhibitors

By Gaurav Chaudhary Synthetic Lethality  0 Comments

After a strong showdown at ESMO 2019, both GSK and AstraZeneca have reignited the fight of small molecule anti-cancer drugs against the industry’s brawny immunotherapy push. Leading this fight is poly(ADP-ribose) polymerase (PARP) inhibitor, one of the leading synthetic lethality targets. These better than expected results at ESMO further validate the potential of synthetic lethality

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August 7, 2019

Mitochondrial Disease Therapies: Unlocking Treatment for Orphan Diseases

By Arun Gupta Mitochondrial Disease  0 Comments

In the US, mitochondrial diseases are known to annually affect 1 in 5,000 individuals. It is also estimated that 1,000-4,000 children are born with a mitochondrial disease every year, in the same region. Primary mitochondrial diseases are usually difficult to diagnose. Such clinical conditions are rare and are known to affect multiple parts of the

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July 18, 2019

Abuse Deterrent Formulation Technologies: Combating Prescription Drug Abuse

By Arun Gupta Abuse Deterrence, Pharmaceuticals  0 Comments

Although the healthcare industry relies on the patient to take medications responsibly; in 2017, close to 18 million individuals were reported to have misused prescription drugs, in the US. In fact, data from a National Survey on Drug Use and Health conducted in the same year, showed that an estimated 2 million Americans misused prescription

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July 17, 2019

Natural Killer Cell Therapies: Pipeline Review

By Arun Gupta Cell Therapy, Natural Killer Cells  0 Comments

Natural killer (NK) Cell Therapies , or killer (K) cells, represent an important subset of cellular mediators of the innate immune system. These cells are known to be instrumental in containing viral infections and regulating tumor development, while the adaptive immune system generates an antigen-specific response. Several studies have demonstrated the various benefits of NK

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July 12, 2019

Vaccine Manufacturing: Current Landscape and Future Potential

By Arun Gupta Contract Manufacturing, Vaccines  0 Comments

The global vaccine manufacturing market is anticipated to generate revenues worth USD 100 billion by 2025. According to the WHO, the global vaccination rate is nearly 85%, demonstrating the high clinical demand for vaccines. In addition to meeting the growing demand for vaccines, the developers of these pharmacological interventions are also plagued by high costs

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July 12, 2019

T-Cell Immunotherapy: The Goldrush Continues

By Arun Gupta Cell Therapy, Therapeutics  0 Comments

The cancer therapeutics market is considered to be one of the most active segments within the pharmaceutical industry. In the past five years, the USFDA has approved more than 100 drugs for the treatment of different types of cancer. According to the International Agency for Research on Cancer (IARC), close to 17 million new cases

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May 30, 2019

Medical Devices: The Growing Opportunities for CMOs

By Arun Gupta Medical Devices and Technology  0 Comments

In 2020, the global medical devices market is estimated to reach a net worth of approximately USD 430 billion. However, most developers lack adequate resources and the necessary expertise to manufacture medical devices and related components. Given the rise of medical device CRO, the opportunity for CMOs with expertise in medical devices is also steadily

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May 28, 2019

Neoantigen Targeted Therapies: Mapping the Future Growth Potential

By Arun Gupta Oncology  0 Comments

The World Health Organization has estimated the number of new cancer cases, reported across the globe, to rise by 70% over the next 20 years. Conventional treatment options, such as chemotherapy, surgery and radiation therapy, continue to demonstrate limited efficacy in late-stage cancers. Recent developments in genomic analysis and advances in bioinformatics have enabled the

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May 16, 2019

Biologics Fill / Finish Services: Current Landscape, Growth Opportunities and Future Market Outlook

By Arun Gupta Biologics  0 Comments

According to a recent CDMO survey, about 54% respondents claimed to have collaborated with a contract service provider for clinical and commercial-scale product development projects. Specifically, fill / finish is the final step in the production process and is considered among the most crucial stages of drug product manufacturing. Biologic drug products require special procedures

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May 9, 2019

Caps and Closures for Parenteral Containers Market

By Arun Gupta Pharmaceutical Packaging  0 Comments

The use of elastomeric materials, along with various types of coatings (such as FluoroTec® and Teflon®) have emerged as a promising alternative to conventional, non-coated caps and closures used for primary packaging containers, which were prone to leaching and shedding of particulate contaminants. The advantages of using Medical polymers in manufacturing container caps and closures

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April 30, 2019

Cancer Biomarkers Market: Focus on TMB, MSI / MMR and TILs Testing

By Arun Gupta Cancer  0 Comments

Advances in biotechnology have enabled the development of several high throughput tools, which have led to the establishment of better biomarkers based on genome / exome profiles. Novel biomarkers, such as tumour mutation burden (TMB), microsatellite instability (MSI) / mismatch repair (MMR) deficiency, tumour infiltrating lymphocytes (TILs) and certain others, are presently being investigated across

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April 29, 2019

Novel Clinical Trial Service Providers: Focus on RWD, Virtual Trials, Adaptive, Umbrella and Basket Designs

By Arun Gupta Clinical Trials  1 Comment

Studies suggest that each prescription drug requires around 10 years and over USD 2.5 billion in working capital before it reaches the market. Further, it is estimated that, in the US, 40% of the pharma industry’s R&D budget is spent solely on conducting clinical trials. Estimates suggest that nearly 85% of Novel Clinical trials fail

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April 25, 2019

Depressive Disorders: Pipeline Review, Developer Landscape and Competitive Insights

By Arun Gupta Depressive Disorders  0 Comments

It has been estimated that over 300 million people (considering all age groups) suffer from depression worldwide. Depressive disorders are estimated to be responsible for an economic burden of up to USD 210 billion per year in the US. Since the 1950s, around 30 branded drugs and more than 150 generic products have been approved

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April 24, 2019

CDX: The Road Ahead for Personalized Therapies

By Arun Gupta Diagnostics  0 Comments

It is estimated that nearly 50% of prescribed drugs / therapies fail to show adequate clinical benefits. It is also worth highlighting that companion diagnostics (CDX) guided drug development efforts have been estimated to help reduce clinical trial costs by almost 60%. Since the approval of the HercepTest (in 1998) for identifying patients for treatment

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April 2, 2019

Biopharmaceutical CMO: The Growing Need

By Arun Gupta Biopharmaceutical  0 Comments

Over the years, the biopharmaceutical market has grown into a prominent and promising segment of the overall pharmaceutical industry. Owing to the growing number of start-ups that are engaged in R&D of novel biologics, there is significant opportunity for the biopharmaceutical CMOs in this domain. It is worth highlighting that, since 2000, more than 115

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March 28, 2019

The Emergence of Encapsulated Cell Therapies and Affiliated Technologies

By Arun Gupta Cell encapsulation, Cell Therapy  0 Comments

Extensive research on  Cell Therapies encapsulation strategies have enabled the development of a variety of technologies capable of confining therapeutic entities within biocompatible matrices / carriers. Since 2013, over 3,000 patents have been published related to the aforementioned type of therapy, indicating the rapid pace of R&D activities in this domain. I have highlighted below

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March 14, 2019

Bone Cement Delivery Systems: Current Landscape, Growth Opportunities and Future Market Outlook

By Arun Gupta Delivery Systems, Uncategorized  0 Comments

According to a study conducted by the International Osteoporosis Foundation (IOF), more than 200 million individuals around the world suffer from osteoporosis. In fact, a total of 8.9 million fractures per year are attributed to osteoporosis. The annual socioeconomic burden associated with this condition is estimated to be around USD 19 billion and EUR 37

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March 11, 2019

Cybersecurity in Healthcare: The Impending Threat

By Arun Gupta Cybersecurity, Healthcare  0 Comments

Organizations, in the process of collating and storing huge volumes of data on digital platforms, end up placing themselves at enormous risk of losing valuable information to cybercriminals. Estimated annual losses attributed to cyberattacks committed globally, amount to over USD 100 billion. The year 2017 witnessed several cyberattacks; notable examples include WannaCry and NotPetya ransomware

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March 7, 2019

Alzheimers Market: Developer Landscape and Competitive Insights

By Arun Gupta Alzheimer's Disease  0 Comments

It was estimated that, in 2018, nearly 5.7 million Americans (considering all age groups) were living with Alzheimers. During the same year, Alzheimer’s pipeline and other dementias were projected to be responsible for a healthcare burden amounting to USD 277 billion, in the US. Despite extensive research aimed at comprehending the etiopathogenesis of Alzheimers, only

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March 1, 2019

Stem Cell Therapies: Upcoming Opportunities in Cardiovascular and Metabolic Disorders (CVMD)

By Arun Gupta Cell Therapy, Stem Cells  0 Comments

Cardiovascular disorders and metabolic disorders are considered to be amongst the leading causes of death worldwide. In fact, approximately one-third of the annual number of deaths across the globe are attributed to cardiovascular disorders.  Likewise, a significant proportion of the global population suffers from diabetes or some form of metabolism related clinical condition. As per

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February 26, 2019

Clinical Trial Patient Recruitment: Market Trends and Opportunities

By Arun Gupta Contract Service Providers, Patient Recruitment  0 Comments

It is estimated that 80% of studies do not meet their designated clinical trial patient recruitment deadlines. In addition, retaining patients is also a matter of concern, considering that the approximate dropout rate across clinical studies is around 30%. Delays in product launch, due to inability of proper clinical trial patient recruitment / retention practices,

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February 20, 2019

Next Generation Contact Lenses and Visual Prosthesis: Rising Popularity to Drive a Multibillion Dollar Market

By Arun Gupta Ophthalmic Lenses, Visual Prosthesis  0 Comments

For more than five decades, contact lenses have primarily been used to correct vision-related disorders. The existence of several unmet needs in the field of ophthalmology, recent technological advances and the availability of new biomaterials, have substantially expanded the range of potential application areas for contact lenses. It is also worth highlighting that Visual Prosthetics,

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January 31, 2019

Drug Delivery Technologies: Shaping the Future of Biologics

By Arun Gupta Biologics, Drug Delivery  0 Comments

Given their high target specificity and limited toxicity compared to small molecule drugs, biotherapeutics have revolutionized treatment paradigms across a myriad of clinical conditions, including metabolic disorders, cancers, neurological disorders and autoimmune disorders. In fact, the extent of growth of such therapies can be gauged from the fact that more than 300 biopharmaceuticals have been

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January 24, 2019

In Vitro ADME Testing: The Rise of Service Providers

By Arun Gupta ADME Testing, Contract Research Organizations, Drug Discovery  0 Comments

It is important to note that the process of drug discovery is extremely demanding, both in terms of capital and time. In fact, the overall amount spent on R&D initiatives in the pharmaceutical / biotechnology sector has increased from around USD 128 billion in 2008 to USD 165 billion in 2018. Moreover, only a small

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December 6, 2018

On Body Injector: The Goldrush Continues

By Arun Gupta Drug Delivery, Medical Devices and Technology  0 Comments

The on body injector market is currently characterized by the presence of a myriad of advanced and innovative drug delivery technologies, equipped with a variety of user-friendly features. Notable examples of such products include prefilled syringes, reusable and disposable pen injectors, autoinjectors and large volume wearable injectors. On body injector is capable of drug delivery

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November 15, 2018

Chronic Kidney Disease (CKD) Market: Pipeline Review, Developer Landscape and Competitive Insights

By Arun Gupta Chronic Kidney Disease  0 Comments

It is worth highlighting that over 90% of the patients suffering from reduced kidney function are unaware of their medical condition. In the US, 15% of adults are reported to be suffering from mild or severe forms of Chronic Kidney Disease. In fact, the mean global prevalence of CKD, across all five stages of the

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November 6, 2018

Blockchain Genomic Data Management

By Arun Gupta Antibodies, Biologics, Cell Therapies, Contract Research Organizations, Healthcare, LIFESTYLE  0 Comments

It is estimated that, by 2025, around 15% of the world’s population will have had their genomes sequenced, resulting in the generation of several zettabytes of data. However, currently, there are not many reliable and secure data management resources that offer secure storage, seamless exchange of information, and a reliable transaction platform, for large volumes

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October 26, 2018

Drug Adherence Enhancement: Novel Approaches to Drive Future Growth

By Arun Gupta Drug Adherence, Medical Devices and Technology  0 Comments

It has been estimated that, of the ~4 billion annual prescriptions filled by the retailers in the US,  approximately 50% are not taken by patients in accordance to physicians’ instructions.  According to the US Centers for Disease Control and Prevention (CDC), failure to comply to prescribed treatment regimens has been identified as the cause of

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October 18, 2018

The Rise of Cell and Gene Therapy CRO

By Arun Gupta Cell Therapies, Contract Research Organizations, Gene Therapy  0 Comments

Over 500 cell and gene therapy candidates are being investigated in different stages of clinical development across various geographies. In fact, in the past five years alone, more than 1,000 clinical trials, that are currently active, were initiated to evaluate the potential of these cell and gene therapies across multiple therapeutic indications. Due to several

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October 5, 2018

RWE: Unearthing the Gold Mine

By Arun Gupta Contract Research Organizations, Healthcare  0 Comments

Estimates suggest that each prescription drug requires an average of about 10 years and over USD 2.5 billion in working capital before it gets commercialized. In order to gain regulatory approval and establish standards for the safety and efficacy of these products, randomized clinical trials (RCTs) are conducted; these account for a staggering 40% of

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October 4, 2018

The Rise of Medical Device CROs

By Arun Gupta Contract Research Organizations, Medical Devices and Technology  0 Comments

According to the World Bank, more than 50,000 different types of Medical Device are currently being used every day in health care facilities worldwide.  In 2018, the global medical devices market is estimated to reach a net worth of approximately USD 450 billion. However, a relatively larger proportion of device developers lack the required internal

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September 27, 2018

Ready to Use Pharmaceutical Packaging: Trends and Opportunities

By Arun Gupta Pharmaceutical Packaging, Pharmaceuticals  0 Comments

The ready to use of pharmaceutical primary packaging has emerged as a promising alternative to conventional primary packaging, adding significant value to streamline pharmaceutical fill / finish operations. These packaging components eliminate multiple steps in the overall fill finish manufacturing (mainly washing, sterilizing and preparing containers), thereby, helping improve operational efficiencies in compliance to existing 

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September 27, 2018

Cold Chain Logistics: Opportunities in Cell Therapies and Vaccines

By Arun Gupta Cold Chain, Logistics  0 Comments

Presently, a wide variety of pharmaceutical products, such as biologics, vaccines, human organs for transplantation and certain conventional pharmacological interventions as well, are temperature sensitive and require freezing / cryogenic holding temperatures. In fact, over 95% of all approved biologics and 90% of all vaccines are cold chain logistics dependent.  Stakeholders in this segment have

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September 25, 2018

Extractables and Leachables Testing: Emerging Opportunities

By Arun Gupta Medical Devices and Technology, Pharmaceuticals  0 Comments

During drug product manufacturing and fill / finish, it is important to consider not only the impurity profiles of the drugs, but also identify potential sources of contamination in the containers / packaging material used. due to high variability in the type of impurities (organic (volatile, non-volatile or semi- volatile compounds) or inorganic (metals or

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September 11, 2018

ADC Manufacturing: Current Landscape and Growth Opportunities

By Arun Gupta Antibodies, Biologics  0 Comments

Antibody drug conjugates (ADCs) are one of the most popular classes of targeted therapeutic agents and have captured the attention of both large and small pharmaceutical companies, and academic / research institutions across the world. Owing to the fact that these novel conjugates act as cytoxic drugs and HPAPI molecules, their manufacturing requires elaborate technical

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September 4, 2018

Neurostimulation Devices: Competitive Landscape, Market Evolution and Opportunity Areas

By Arun Gupta Medical Devices and Technology  0 Comments

Extensive research in the field of Neurostimulation has demonstrated the potential of this technique in providing therapeutic relief to a number of patients, who have developed resistance to conventional medication. Since the introduction of the first neurostimulation therapy in 1960s, their numerous observed benefits, such as reversible and minimally invasive nature of the procedures (to

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August 23, 2018

Antibody Discovery Market: Rise of Platform Providers

By Arun Gupta Antibodies, Biologics, Immunotherapy  0 Comments

Owing to several beneficial features, such as high specificity, and a favorable safety profile, antibody (Ab) discovery based pharmacological interventions, with 79 molecules approved till date and over 200 molecules in the preclinical / discovery stages, presently represent the largest class of biologics. The antibody discovery market involves a long, arduous and cost intensive process.

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August 2, 2018

Chronic Pain Management: Path to USD 10 Billion+ Opportunity

By Arun Gupta Healthcare, Medical Devices and Technology  0 Comments

Owing to the rapid onset of their medicinal effect, which offers immediate relief with high efficacy, opioids are still considered to be one of the most widely used pharmacological interventions for the management of moderate to severe forms of pain. However, these drugs are known to induce a euphoric state upon intake, often causing patients

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July 13, 2018

T Cells: The Future Roadmap of The USD 15 Billion+ Opportunity

By Arun Gupta Biologics, Cell Therapies, Future Perspectives, Immunotherapy, Oncology, Uncategorized  0 Comments

Although cancer therapeutics continue to be one of the most active areas in terms of drug development, there is still a significant unmet need in this domain. Conventional cancer treatments, such as chemotherapy, surgery and radiation therapy, have demonstrated very limited efficacy in late-stage cancers. Amidst the current initiatives to develop more targeted anti-cancer therapies,

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July 11, 2018

Cell Therapy Manufacturing: The $ 8 Billion+ Growth Opportunity

By Arun Gupta Cell Therapies, Future Perspectives, Immunotherapy, Therapeutics  0 Comments

Cell Therapy Manufacturing market has gained significant attention in the overall biopharmaceutical industry. The personalized nature of these cell therapies options render them highly specific and, according to a number of clinical studies, safe and efficacious. Around 20 such therapies have been approved so far; recent approvals include Alofisel® (2018), YESCARTA® (2017) and Kymriah® (2017).

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July 5, 2018

The Meteoric Rise of Digital Therapeutic, Monitoring and Diagnostic Solutions

By Arun Gupta Diagnostics, Therapeutics  0 Comments

Chronic disorders, such as diabetes, heart disease, obesity, mental health problems and insomnia, are considered to be the leading causes of death and disability across the world.  According to a 2018 report published by the Center for Managing Chronic Disease at the University of Michigan, more than 50% of the global population currently lives with

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June 27, 2018

CADD: Opportunities to Optimize the Growing R&D Expenses

By Arun Gupta Drug Discovery, Pharmaceuticals  0 Comments

Given the increase in complexity of the drug discovery process, the overall R&D spending in the pharmaceutical contract manufacturing / biotechnology sector has grown from around USD 128 billion in 2008 to USD 158 billion in 2017. As a result, the industry is currently under tremendous pressure not only to meet the expectations of a

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May 23, 2018

Parkinson’s Disease: Pipeline Review and Competitive Insights

By Arun Gupta Parkinson’s Disease  0 Comments

Parkinson’s disease is known to affect 1-2 per 1,000 individuals and has been shown to impact approximately 1% of the population aged above 60 years. The disease has been estimated to incur combined direct and indirect costs of close to USD 25 billion in the US annually. Despite the availability of several types of dopamine

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May 16, 2018

Automatic injector: Current Opportunities and Future Growth Areas

By Arun Gupta Autoinjectors, Pharmaceuticals  0 Comments

Since the introduction of the automatic injector (autoinjectors) device in 1980s, their numerous benefits, such as ease-of-use, reduced chances of dosing errors, integrated safety mechanisms, and almost negligible risk of needlestick injuries, have been widely recognized among consumers and healthcare service providers. Automatic injector are also considered to be potential life cycle management tool. Drugs

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April 27, 2018

Drug Bioavailability Enhancement: Growth Opportunities

By Arun Gupta Pharmaceuticals  0 Comments

Low drug bioavailability is one of the primary concerns associated with marketed medications; in fact, various studies indicate that around 40% of available drugs are poorly bioavailable / soluble. As the drug developers shift their focus towards development of lipophilic drug compounds, the issue with aqueous solubility / drug bioavailability is likely to be increase

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April 25, 2018

Next Generation Batteries: Mapping the Future Potential

By Arun Gupta Li-ion batteries  0 Comments

In contrast to the conventional Li-ion batteries, next generation batteries, which include lithium polymer, solid-state, thin film and printed batteries, have been proven to be safe under abusive conditions, demonstrated significant improvements in terms of overall performance, and are environmental-friendly. Moreover, owing to their flexible form factor, it is believed that these batteries can offer

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April 19, 2018

Pharmaceutical Spray Drying: Trends and Growth Opportunities

By Arun Gupta Biologics, Pharmaceuticals  0 Comments

Spray drying, which is already established in the food and chemical sector, is also considered to be a rapid, cost-effective, and scalable process for the production of dry powder formulations of pharmacological material. Owing to characteristics, such as reproducibility and its continuous mode of operation, the technique has become very popular in the pharmaceutical contract

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April 17, 2018

T-Cell Immunotherapies: The Goldrush Continues

By Arun Gupta Biologics, Immunotherapy, Oncology  0 Comments

Amidst the current initiatives to develop more targeted anti-cancer therapies, immunotherapy has emerged as a highly potent option to eradicate tumor cells with minimal side effects. It is based on the principle of harnessing the innate potential of the immune system to target and destroy diseased cells. It encompasses several treatment approaches, such as monoclonal

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March 28, 2018

Oral Peptides and Proteins: The Growing Importance

By Arun Gupta Biologics, Healthcare, Oral Delivery, Therapeutics, Uncategorized  0 Comments

Oral peptides and protein-based therapeutics have been in use for more than three decades since the approval of recombinant human insulin, the first protein therapy, in 1982. Earlier, most biologic drugs were the subcutaneous biologics. However, over time, advances in delivery formulations have enabled the development of oral peptides / proteins. Owing to numerous compelling

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February 21, 2018

Gene Therapies: Mapping the Future Growth Potential

By Arun Gupta Future Perspectives, Gene Therapy, Healthcare, Immunotherapy, Oncology, Pharmaceuticals, Therapeutics  1 Comment

The first gene therapy, Gendicine®, was only approved in 2003 in China; since then, the domain has evolved significantly. The ‘Gene Therapy Market (2nd Edition), 2018-2030’ report provides an extensive study on the current market landscape of gene therapies, with a prime focus on gene augmentation based therapies and oncolytic viral therapies, featuring an elaborate discussion on

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February 8, 2018

Smart Grids: Current Market Landscape and Future Opportunities

By Arun Gupta Smart Grids  1 Comment

 With growing electricity consumption, the peak electricity demand is expected to increase manifold by 2050. It is believed that, owing to their intelligence features, smart grids have the potential to reduce the projected peak demand increases by up to 24% across some of the major regions of the world. This is because sensors in smart

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February 6, 2018

Respiratory Disorders: Mapping the Future Potential

By Arun Gupta Future Perspectives, Healthcare, Therapeutics  0 Comments

The World Health Organization (WHO) estimates the global prevalence of two of the most common chronic respiratory disorders, namely asthma and chronic obstructive pulmonary disease (COPD), to be around 335 million and 400 million patients respectively. According to the data provided by the WHO, more than 3 million people die annually from COPD. Asthma, on

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December 15, 2017

Back of the Eye Disorders: Novel Drugs and Delivery Technologies

By Arun Gupta Future Perspectives, Medical Devices and Technology, Pharmaceuticals  0 Comments

The current treatment landscape for back of the eye disorders is characterized by the presence of blockbuster novel ophthalmic drugs, such as Lucentis® and Eylea®, and various other therapeutic options. Despite the success of these therapies, their invasive mode of administration, high dosage frequency and other drug related side effects, are some of the drawbacks

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December 6, 2017

Cancer Stem Cell Therapies: Mapping the Future Growth Potential

By Arun Gupta Cell Therapies, Pharmaceuticals  0 Comments

The objective of the ongoing R&D in this domain is to develop novel CSC directed treatments that can combat complications, such as off-target toxicities and disease relapse, associated with the current standard of care treatments. The ‘Cancer Stem Cell Therapies Market, 2017-2030’ report examines the current landscape and the future outlook of the growing pipeline of products

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November 20, 2017

3D Bioprinting: What Lies Ahead?

By Arun Gupta 3D Bioprinting  0 Comments

The current applications of 3D bioprinting products cater to various requirements within the pharmaceutical industry for clinical testing of therapeutic drugs. The ‘3D Bioprinting: Technologies, Products and Key Application Areas, (2nd Edition), 2018-2035’ report provides a comprehensive study on the current market landscape of the 3D bioprinting industry, featuring an elaborate discussion on the future potential of this evolving

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November 17, 2017

Non-Antibody Protein Scaffolds: A Niche but Highly Promising Opportunity Area

By Arun Gupta Non-Antibod  0 Comments

Amongst other novel formats, non-antibody protein scaffolds have emerged as viable alternatives to conventional therapies, having the capability to address the existing challenges associated with classical antibody based therapies. The ‘Non-Antibody Protein Scaffolds Market‘ report provides a comprehensive study of the current market landscape , and related drugs and diagnostics, featuring an elaborate discussion on the likely future

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October 26, 2017

Antibody Drug Conjugates Market: Riding on the Growth Wave

By Arun Gupta Oncology, Pharmaceuticals, Therapeutics  0 Comments

While there are close to 200 ADCs in various stages of development, the market field is currently going through a gradual transition, shifting from relying on conventional technologies to newer approaches for generating ADCs. The ‘Antibody Drug Conjugates Market (4th Edition), 2017-2030’ report provides a comprehensive study on the current landscape of ADCs, featuring an elaborate discussion

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October 25, 2017

Biopharma Contract Manufacturing: From Promise to Reality

By Arun Gupta Biopharmaceutical  0 Comments

The development and manufacturing processes opted by biologics CMO are complex, and usually require advanced capabilities and specialized expertise. This has led many stakeholders in the industry to outsource significant parts of their business operations to biopharma contract manufacturing service providers. The ‘Biopharmaceutical Contract Manufacturing Market (2nd edition), 2017 – 2027’ report provides an extensive study of

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October 20, 2017

Cell Line Development: Landscape and Future Market Evolution

By Arun Gupta Cell Line, Diagnostics, Future Perspectives  0 Comments

Cross contamination and cell line misidentification are some of the major concerns associated with the use of cell lines. It has been estimated that a net loss of USD 28 billion is incurred every year on research that cannot be replicated due to the involvement of misidentified or contaminated cell lines in the US. To

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October 18, 2017

Antibody Discovery Platform: An Opportunity Platform Providers

By Arun Gupta Antibody Discovery  0 Comments

The rising demand for novel antibody therapy and personalized medicines to provide targeted treatment options has encouraged pharmaceutical companies to shift their focus from small molecules to discovery and development of biologics, particularly antibody-based therapeutics. The antibody discovery platform report provides an extensive study on the current market landscape and future outlook of the antibody discovery service

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October 6, 2017

Modular Facilities in Pharma / Biotech: An Evolutionary Leap Forward

By Arun Gupta Biotech  0 Comments

Modular facilities have demonstrated tremendous potential in several fields; specifically, the shorter time taken to establish such facilities has a significant impact on expediting various operational processes. The modular construction market report provides an extensive study on the current market landscape and future outlook of modular facilities manufacturers that cater to the demands of pharmaceutical

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September 28, 2017

3D Cell Cultures: A Multi-Billion Dollar Growth Opportunity

By Arun Gupta 3D Cell  0 Comments

The use of advanced 3D cell culture techniques in in vitro studies is seen to have the capability to overcome several challenges associated with 2D systems. The ‘3D Cell Cultures: Products, Technologies and Key Application Areas (2nd Edition), 2017-2030’ report features an extensive study on the various scaffold-based and scaffold-free 3D cultures system. Some of

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September 27, 2017

Bispecific Antibodies: Current Market Trends and Future Outlook

By Arun Gupta Antibodies  0 Comments

Bispecific antibodies have demonstrated the capability to address the existing challenges associated with the current novel antibody therapy market, such as high manufacturing costs, limited applicability in assays and the general lack of understanding of precise in vivo mechanisms of action. The bispecific antibodies market report provides a comprehensive study of the current landscape of bispecific antibodies,

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August 31, 2017

Deep Learning: Opportunities in Drug Discovery and Diagnostics

By Arun Gupta Drug Discovery  0 Comments

Deep learning is a novel machine learning technique that can be used to generate relevant insights from large volumes of data. The applications of the technology are being explored across a variety of areas. The ‘Deep Learning: Drug Discovery and Diagnostics Market, 2017-2035‘ report examines the current landscape and future outlook of the growing market of

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August 31, 2017

Liquid Biopsy: Will It Be The Future Gold Standard?

By Arun Gupta Liquid Biopsy  0 Comments

Invasive cancer diagnostic methods, such as tissue biopsies, have been the gold standard to determine the clinicopathological characteristics of cancer tissues for many years. The procedure is not only cost-intensive but is also a traumatic experience for the patients. The ‘Non-Invasive Cancer Diagnostics Market (2nd Edition), 2017-2030’ report provides an extensive study on liquid biopsy kits /

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August 31, 2017

Cell Therapy Manufacturing: A Niche but Rapidly Growing Multi-Billion Dollar Industry

By Arun Gupta Cell Therapy  0 Comments

Post the approval of first cell-based therapy, Carticel®, in 1997 in the US, the field has rapidly advanced and a number of such therapies are currently under development. The ‘Cell Therapy Manufacturing Market, 2017-2027‘ report provides an extensive study of the rapidly growing market of cell therapy manufacturing and focuses both on contract manufacturers and cell

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August 31, 2017

Bolu Injectors: The Goldrush Continues

By Arun Gupta Injectors  0 Comments

The large scale adoption of prefilled syringes demonstrated the growing interest in the concept of such convenient drug delivery systems. Large volume wearable injectors (also termed as bolus injectors) are advanced versions of the existing self-injection devices. The ‘Large Volume Wearable Injectors Market (3rd Edition), 2017-2027′ report features an extensive study of the current landscape and the

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August 24, 2017

Antibody Humanization and Affinity Maturation: Current Market Landscape and Opportunity Areas

By Arun Gupta Antibody Humanization  0 Comments

Certain steps of antibody drug discovery require advanced expertise, and companies offering these specialized services have attracted significant attention of drug / therapy developers. Two such specific services are to reduce antibody immunogenicity (humanization) and enhance its affinity (affinity maturation). The ‘Antibody Humanization and Affinity Maturation: Services and Platforms, 2017-2030′ report provides a comprehensive view on the current landscape and the

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August 3, 2017

Cell Line Development: A Gold Mine for Service Providers

By Arun Gupta Cell Line, Pharmaceuticals  0 Comments

Owing to their use in the manufacturing of biologics and biosimilars, and various application areas, such as drug screening, gene functional studies, cell-based assay development, diagnostics and tissue engineering, there is growing demand for different types of cell lines. The ‘Cell Line Development Services Market, 2017 – 2027’ report provides an extensive study of the rapidly growing market

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August 3, 2017

Microbiome Therapeutics and Diagnostics: Unlocking the Future Potential

By Arun Gupta Diagnostics, Future Perspectives, Microbiology, Therapeutics  0 Comments

Microbiome therapeutics represent a new frontier in the field of medicine. Currently, there are many probiotics, prebiotics, and medical foods and supplements that are commercially available, and several drug / therapy candidates that claim to be capable of modifying / manipulating the microbiome in order to provide therapeutic benefits. The ‘Human Microbiome Market’ report provides a comprehensive study on the current

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August 2, 2017

T-Cell Immunotherapy: The Next Big Thing in Immunotherapeutics

By Arun Gupta Immunotherapy, Pharmaceuticals  0 Comments

The concept of immunotherapies dates back to the 18th century; however, since its inception, the field has evolved tremendously and is currently cited as one of the most rapidly growing segments of the pharmaceutical industry. Post the early success of immune checkpoint inhibitors, T-cell immunotherapy has emerged as another innovative and potent arm of this market.

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January 20, 2017

Superbugs: The Growing Concern Related to Antibiotic Resistance

By Arun Gupta Future Perspectives, LIFESTYLE, Pharmaceuticals  0 Comments

The Centers for Disease Control and Prevention (CDC) estimates that over two million  people suffer from life threatening infections caused by drug resistant strains of bacteria every year, in the US. According to a report published in the UK, the global death toll due to the current ADR crisis is likely to reach as high as 10

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November 14, 2016

Fake Medicine: The Perils of Pharmaceutical Counterfeiting

By Arun Gupta Pharmaceuticals  0 Comments

When it comes to taking medicine, we usually have blind faith in what the Pharmaceutical hands us and consume it without a second thought. The thought that a prescription drug may be a fake medicine or even harmful does not generally cross our minds. However, the issue of fake medicine is more serious than we

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August 22, 2016

Cancer Stem Cell: A Step Closer to the Cure

By Arun Gupta Oncology  0 Comments

The discovery of cancer stem cell (CSC) may have revolutionized the field of cancer research in a manner similar to how the “germ theory of disease” altered the way medical science looked maladies in general.  Before the germ theory, disease and sicknesses were attributed to be manifestations of bad omens and evil spirits. The discovery of

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August 22, 2016

Gene Editing Companies: Future Potential and Ethical Concerns

By Arun Gupta Gene Therapy  0 Comments

Gene editing companies around the word are debating the scientific and ethical possibilities of using powerful genome editing tools, such as the CRISPR gene editing therapies, to treat heritable diseases in human embryos. In 1987, the discovery of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) genes in single celled prokaryotic systems revolutionized genetic engineering.

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July 15, 2016

Social Media in Pharmaceutical Marketing

By Arun Gupta Pharmaceuticals  0 Comments

The importance of the pharmaceutical industry as a global sector is undeniable. In 2014, pharmaceutical sales reached a milestone of USD 1 trillion. Apart from discovering and developing innovative healthcare solutions, pharmaceutical companies also need to market and promote their products to remain profitable. It is worth mentioning that the sales and distribution of pharmaceutical

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June 15, 2016

Generic Drugs: Rising Opportunity for Indian Pharmaceutical Players

By Arun Gupta Generic Drugs, Pharmaceuticals  0 Comments

India is en route to becoming a powerful and dynamic nation. Numerous initiatives undertaken by both the private and public sectors have been launched to revolutionize the way the nation operates. Prominent examples include the smart cities initiative, introduction of high speed trains, and the extensive efforts by the current Prime Minister, Mr. Narendra Modi,

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