Injected Version of Eisai/Biogen Alzheimer’s Drug Works as Well as IV Leqembi
On 26 October 2023, Eisai and Biogen’s Alzheimer’s drug, Leqembi, was found to be as effective as the current intravenous administration in removing toxic brain plaques. However, the review conducted by the drugmakers revealed that the rates of serious side effects were higher when using the drug in its subcutaneous injection form. The company’s analysis compared data from 72 early Alzheimer’s patients who received Leqembi through subcutaneous injection to prior pivotal trial results from 898 patients who received the drug via infusion.
During the presentation of the latest data at the Clinical Trials on Alzheimer’s Disease, it was revealed that after six months of treatment, the subcutaneous version of Leqembi removed 14% more amyloid plaques than the approved intravenous formulation. Additionally, blood concentration levels of the drug were 11% higher with the subcutaneous Leqembi compared to the intravenous version. Furthermore, the company’s conclusion was that the rates of side effects related to the infusion or injection were lower for the subcutaneous formulation, but the rates of serious side effects were higher.
According to Roots Analysis, the Alzheimer’s Market is estimated to be worth $7.6 billion in 2022 and is expected to grow at a CAGR of 12% during the forecast period.
For detailed insights about this domain, check out our report on Alzheimer’s Market or email sales@rootsanalysis.com
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Arun_Gupta
Arun is an enthusiastic professional and has been associated with Roots Analysis since the very early years. He has led multifaceted roles over the years be it business research, consulting, competitive intelligence, IT & technology, sales and marketing. He currently drives strategic thinking and execution within the sales and marketing domain. With educational background in life sciences from Thapar University and digital marketing credentials from Indian School of Business, he has led a lot of critical initiatives at the organization. His background in life sciences has been one of the key reasons for quick understanding and implementation of customized marketing strategies. During his early years, he has led multiple consulting assignments for global clients ranging from competitive landscaping, deal structuring and preparing go-to-market strategy for his clients.