Cancer diagnosis, today, employs a mix of invasive and non-invasive strategies. Invasive cancer diagnostic methods are generally expensive and uncomfortable. Biopsies have been the gold standard to determine the clinicopathological characteristics of cancer tissues for many years. The procedure is very uncomfortable and painful for patients and in many cases, the results are known to be negative. On the other hand, non-invasive methods are quicker, need no elaborate preparation before the procedure, and the subject can return to his/her daily activities almost immediately after the procedure.