Chromatography finds several applications across different industries, including pharmaceutical, biotechnology, chemical, environmental, food, petrochemical, and other such industries. Specifically in pharmaceutical industry, recent years have witnessed a surge in the demand for chromatography systems / chromatography instrumentation (such as liquid chromatography system, gas chromatography system, gel permeation chromatography, supercritical fluid chromatography) and chromatography consumables (such as chromatography resin, packed columns) used for the qualitative and quantitative analysis of a wide range of complex samples in large-scale translational research studies, precision medicine, virus research and vaccines development.
Further, the outbreak of COVID-19 pandemic fueled the growth of the global market of chromatography instrumentation and chromatography consumables; this can be attributed to the adoption of chromatography in various drug development processes and diagnostics. Driven by the rising adoption of chromatography techniques in drug discovery and other application areas, the chromatography instrumentation and chromatography consumables market is anticipated to witness considerable market growth during the forecast period.
Chromatography Instrumentation Companies– Current Market Landscape
Presently, close to 75 large, mid-sized and small companies, which claim to offer various types of chromatography systems, including continuous chromatography system, gas chromatography system, gel permeation chromatography system, ion chromatography system, liquid chromatography system, and supercritical fluid chromatography system, for the detection, separation and purification of various types of analytes. Nearly 70% of the companies offer liquid chromatography systems.
It is worth highlighting that more than 80% companies offer chromatography instrumentation for preclinical scale. In addition, 15 players are offering chromatography instruments for all scales of operations; examples of these players include (in alphabetical order) AAPPTec, Applied Separations, Asahi Kasei, Bio-Rad Laboratories and Knauer.
Chromatography Consumables Companies– Current Market Landscape
Currently, more than 80 companies offer different types of chromatography consumables, including chromatography resin, chromatography columns and others, for a wide range of end users. These companies are providing chromatography consumables that can be used for separation, detection and purification of different types of small molecules, biologics (including amino acids, antibodies, cells, enzymes, oligonucleotides, peptides / proteins) and other analytes.
More than 40% of these chromatography consumables companies are located in North America. It is worth highlighting that in North America, more than 90% of these players are based in the US. In addition, UK, Switzerland, and Germany are the hubs for chromatography consumables companies in Europe. Further, more than 20 chromatography consumables providers are based in Asia Pacific; examples include (in alphabetical order) GL Sciences, Hemochrom, Osaka Soda and Shimadzu.
Emerging Trends in Mergers and Acquisitions by Chromatography Consumables and Chromatography Instrumentation Companies in order to Broaden Product Portfolios
During our research, we came across multiple mergers and acquisitions between various stakeholders in this domain, in order to strengthen their expertise in the chromatography consumables and chromatography instrumentation domain.
It is interesting to note that the number of such deals increased by 37% in 2022, as compared to the deals inked in the previous year. The year 2022 witnessed acquisitions of 10 chromatography system and consumable providers; these include (in alphabetical order) Applied Research, Chromatography Research Supplies, ModuVision, Novasep, Pepsep, Polymer Standards Service, Prolab Instruments, Purologics, Sepiatech, and Virtual Control. Further, Bruker has acquired two companies in the same year; these include (in alphabetical order) Pepsep and Prolab Instruments.
Increasing interest reflective of the significant intellectual capability expansion activity of players engaged in the chromatography instrumentation and chromatography consumables market
Over the past decade, industry and non-industry stakeholders in chromatography systems and consumables have led to the expansion of intellectual capital in this domain. Several patents have been filed by companies / organizations to protect novel intellectual property generated within this field. Over 4,700 patents focused on chromatography have been granted / filed in the past four years, indicating the substantial efforts made by researchers engaged in chromatography instrumentation and chromatography consumables domain. Most of the patents have been filed for the advancement of chromatography instrumentation, chromatography consumables and other accessories. The below figure presents the distribution of filed / granted patents, based on the year and type of patent.
It is worth highlighting that Waters emerged as the leading player, having filed the maximum number of patents in this industry; of these, 58% were filed in the US. This is followed by Regeneron Pharmaceuticals and Merck.
Chromatography Market is Likely to Grow at a CAGR of ~5.6% over the Next Decade
According to our estimates, chromatography consumables and chromatography instrumentation market is estimated to reach over $20.2 billion by 2035, growing at an annualized rate of 5.57%, during the period 2023 to 2035. This opportunity will likely be well distributed across type of product, end user, type of instrument, type of consumable format and key geographical regions. The chromatography instrumentation segment (~80%) is leading the market by type of product followed by chromatography consumables and other accessories. In chromatography instrumentation market, liquid chromatography instruments are anticipated to capture over 50% share followed by gas chromatography and other instruments. Additionally, bottle / bulk resins segment led the market for chromatography consumables and chromatography instrumentation by type of consumable format, capturing more than 45.0% in 2023. This is followed by the pre-packed columns segment, which is anticipated to grow at an annual growth rate of 7% during the forecast period.
Moreover, pharmaceutical / biopharmaceutical companies segment is anticipated to lead the market for chromatography consumables and chromatography instrumentation by type of end user, capturing the majority share of close to 50% in 2023. This can be attributed to the increasing research and development of new drugs and biologics to develop cost effective and user-friendly chromatography solutions. It is worth mentioning that North America and Europe are likely to capture the majority (70%) of the overall share, and this trend is unlikely to change in the future, as well. It is worth highlighting that the market in Asia-Pacific is expected to grow at a relatively healthy growth rate, during the forecast period. Driven by the rising adoption of chromatography techniques in drug discovery and other application areas, the chromatography instrumentation and chromatography consumables market is expected to witness considerable market growth during the forecast period.