On Body Injectors: The Future of Drug Delivery

With the increasing global population, the incidence rates of several chronic disease indications, such as diabetes, heart disorders, neurological disorders and oncological disorders, are on the rise. Therefore, medical technology is rapidly evolving, enabling more advanced and patient-friendly methods of drug delivery. In the pursuit of creating patient-centric healthcare solutions, the medical industry has witnessed a groundbreaking advancement in drug delivery with the emergence of on body injectors. These medical devices are designed to administer drug subcutaneously. These wearable injection device have capability to hold and deliver precise dosages of drugs ranging from a few milliliters to several milliliters. Unlike traditional syringes, these are compact, portable, and can be worn directly on the body, providing patients with a discreet and user-friendly experience. These devices have potential to offer enhanced convenience, improved medication adherence and empowering patients to take control of their treatment regimens. Additionally, it lowers costs associated with needlestick injuries by minimizing the risk to a great extent. The US healthcare industry is reported to endure the cost burden of more than USD 1 billion every year due to these injuries. As a result, wearable injectors have shown a lot of promise to address this problem.

Significance of On Body Injectors

High drug delivery volume: Wearable Injectors have the capacity to deliver higher volumes of drugs in a single administration. This is particularly beneficial for patients who require frequent dosing of high volumes of medication, as it reduces the number of injections they need to endure.

Convenience and portability: These injectors empower patients by providing them with the freedom to administer medication outside of clinical settings. This freedom allows individuals to continue their daily routines without interruption, leading to better treatment adherence and improved health outcomes. This is specifically true for patients using insulin patch pump.

Improved patient compliance: With reduced injection frequency and simplified administration, these on body injectors can lead to better patient adherence to prescribed treatments. Patients are more likely to comply with their medication schedules when the process is less cumbersome and requires fewer interactions.

Precise Dosing and Monitoring: These injectors are equipped with sophisticated software that enables precise dosing and medication scheduling. This level of control ensures that patients receive the right amount of medication at the right time, thereby reducing the risk of adverse reactions and enhancing treatment efficacy.

Enhanced safety and reliability: The devices are designed with safety features, such as dose limiting and error detection mechanisms, which can reduce the risk of medication errors and enhance overall treatment safety.

Reduced Healthcare Burdens: With on body injectors, healthcare providers can minimize the need for frequent visits, particularly for patients requiring long-term therapies. This not only eases the burden on healthcare facilities but also optimizes the allocation of medical resources.

Driving Factors for On Body Injectors

The adoption of on body injectors is increasing due to several driving factors.

Driving Factors for Large Volume Wearable Injectors

Rising Burden of Chronic Diseases: The last few years have witnessed a rising incidence of chronic illnesses across the globe. Long term clinical conditions, such as neurological disorders, cardiovascular disorders, chronic pain and oncological disorders, have been shown to impose a significant burden on the modern healthcare system. and those who suffer from such diseases.

On body injectors simplify this process by offering a convenient and user-friendly solution. Further, by enabling patients to manage their conditions at home with wearable injectors, unnecessary hospitalizations and emergency room visits can be minimized.

Healthcare Cost Savings: The emerging trend of self-injection has been dubbed as a win-win scenario for both patients and healthcare professionals. In addition to being user-friendly and convenient for patients, it saves on healthcare resources and costs by facilitating a lower-cost method to administer medicines, making self-injection system much more cost effective.

Need for Immediate Treatment in Emergency Situations: The need for self-administration is evident in emergency situations, for life-threatening indications, and in conditions where immediate pain relief is required. Such critical situations demand immediate and rapid treatment options. In such cases, devices that enable self-administration can prevent fatality by providing immediate treatment to the patient.

Growing Injectable Drugs Market: Over the past several years, the rapid growth of the biologics and biosimilars market has spurred significant demand for self-injection devices for the treatment of chronic disease indications. Biologics or biological drugs are defined as substances that are derived from living organisms or their by-products. Due to their relatively high specificity (compared to small molecule drugs), the number of biologic drugs reaching the commercial space has notably increased over the past few years. In addition, the global biosimilars market is expected to witness a significant growth owing to the patent expiration of several biologic drugs in the coming years. In fact, there are several biosimilar molecules that have already been commercialized, and many are in the clinical stages of development. Of these, several biologics / biosimilar products have been reformulated as stable liquids to be made available in prefilled syringes for delivery via self-injection devices, such as large volume wearable injectors and autoinjectors. Therefore, self-administration devices are best suited for this class of therapeutics due to the inherent advantages they offer in terms of convenience and safe handling.

Need for Improving Medication Adherence:

Non-adherence to therapy impacts both patients and healthcare providers. For patients, a major long-term consequence for those who refrain from complying with their prescribed medication regimens, is a significant hike in annual healthcare costs. Estimates suggest that, on an average, non-compliant patients suffering from diabetes, hypertension and congestive heart failure typically pay USD 3,700, USD 3,900 and USD 7,800, respectively, in annual treatment costs, accounting for additional treatment for non-compliance.

The modern healthcare industry is now focusing on the development of home-based drug administration devices to provide real-time inputs related to medication management. This has encouraged companies to develop unique devices, such as on body injectors, pen injectors and autoinjectors. Other technological innovations incorporated in these devices enable real-time patient engagement, offering a chance to improve therapy adherence, treatment outcomes and offer enhanced support.

Conclusion

The industry is constantly evolving in the space of drug delivery, with emergence of more convenient and patient compliant systems. As the number of commercially available biologics increases, the need for novel delivery devices is also expected to elevate. The historical trends of existing delivery devices, such as prefilled syringes, autoinjectors and insulin pumps, suggest a strong demand in the market. The wearable injectors market is expected to follow a similar growth trend as more patients shift from conventional to user-friendly drug delivery alternatives. On body injectors represent a paradigm shift in healthcare delivery, offering patients a new level of independence, convenience, and control over their treatment regimens. With the potential to transform various therapeutic areas, these devices mark a significant step towards patient-centric and value-based care. As technology continues to evolve, the future of healthcare looks brighter, due to the revolutionary capabilities of on body injectors.

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