Gene Therapy Funding Update: With a Promise of $100 Million in Funding, US Government Bets Big on Gene Therapy

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In a recent press announcement, The U.S. National Institutes of Health (NIH) has agreed to invest in the development of Gene Therapy in an attempt to cure HIV and sickle cell diseases. The program, for which NIH will partner with The Bill & Melinda Gates Foundation, will involve funding of $100 million each over the next four years.

Agenda of the partnership: 

One of the prime objectives of the partnership is to make the therapies affordable and accessible to people around the world. The focus is primarily on developing countries, where the burden of these diseases is the greatest.

When can we expect the drug: 

While drug development is a highly uncertain domain, as per the agency, the therapy will mostly be ready for testing in clinical trials in the US and sub-Saharan Africa within the next seven to 10 years.

Read the complete coverage here.

Who else is developing gene therapies for Infectious Diseases:

There are a number of companies that are currently developing for infectious diseases. As per the recent gene report by Roots Analysis, there are close to 35 candidates already in development for the treatment of infectious diseases.

The representation of extensive analysis done by Roots team for Gene Therapy development pipeline by phase of development and therapeutic area

How big is the gene therapy pipeline for HIV:

Given the high treatment burden, HIV remains one of the key focus areas of the therapy developers in the infectious disease space. Below, I have added a quick snapshot of the gene therapy pipeline for HIV. Further, post the onset of the COVID-19 pandemic, there has been a steady increase in the investigational new drug (IND) applications filed for cell and gene therapies. In fact, in 2021, more than 200 gene therapies were being evaluated in phase II and III studies.

Moreover, in 2022, six gene therapies are expected to receive the USFDA market approval. Promising results from ongoing clinical research initiatives have encouraged government and private firms to make investments to support therapy product development initiatives in this domain. In 2021 alone, gene therapy companies raised around USD 9.5 billion in capital investments.

The representation of extensive analysis done by Roots team for Gene Therapy development pipeline by target indication (discovery or phase I or II or pre-clinical)

How big is the gene therapy market: The overall gene therapy market is expected to reach close to $12 billion by 2030.

For detailed insights about the market, check out the report Gene Therapy Market report.

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