Cold Chain Logistics: Opportunities in Cell Therapies and Vaccines

Presently, a wide variety of pharmaceutical products, such as biologics, vaccines, human organs for transplantation and certain conventional pharmacological interventions as well, are temperature sensitive and require freezing / cryogenic holding temperatures. In fact, over 95% of all approved biologics and 90% of all vaccines are cold chain logistics dependent.  Stakeholders in this segment have designed and established a variety of innovative solutions to serve the evolving demands. Given the recent technical breakthroughs and advances, and the steadily rising demand for biologics contract manufacturing, the reliance on cold chain logistics is expected to increase substantially, causing service providers to contemplate, devise and implement flexible business strategies and operational models to cope up with the future needs.


Cold chain logistics operations for modern pharmaceuticals are complicated; for temperature sensitive products, cold chain is an indispensable asset in preserving drug integrity and viability


Over 40% of all drugs approved in 2018 are cold chain logistics dependent and have different holding temperature requirements for transportation


Considering that there are a limited number of commercially available cell-based therapies, the short-term demand for cell therapy packaging and logistics is likely to stem from the ongoing clinical trials

There are 73000+ patients enrolled in various cell therapies in North America alone suggesting growing patient population for Cell Therapies as per Roots Analysis

For vaccines, the growing demand can be gauged by the fact that there are close to 1,300 active clinical trials across the globe, sponsored by both industry and non-industry players

more than one third of the Clinical trials are sponsored by Industry for Vaccines

For organ transplants as well, the demand is steadily increasing; transporting live tissues for such delicate procedures requires cryogenic holding temperatures

Within organ demand, Kidney represents almost two third of the global demand followed by liver and heart

Presently, over 85 firms are actively involved in providing cold chain logistics services for healthcare products across a variety of recommended holding temperature ranges


Although the market is dominated by established players, several small and mid-sized players are also offering a wide range of services, striving to attain a competitive edge


Growth in the number of partnerships also reflects the rising interest of industry stakeholders; most of these involved developer companies recruiting the services of logistics providers

Service alliance and logistics service agreements form almost 60% of the partnerships in cold chain logistics as per the study done by Roots Analysis

The adoption of novel tools / techniques, such as artificial intelligence and cloud storage, in cold chain logistics operations is likely to further revolutionize the overall supply chain


Driven by an increasing global demand for biopharmaceuticals, the healthcare cold chain logistics market is currently a multi-billion dollar industry that is anticipated to continue to grow at a steady pace


The overall opportunity is expected to be well-distributed across the various holding temperatures, type of containers and the concerned end-users


To learn more, please click here. For any queries / suggestions, please do not hesitate to contact us at sales@rootsanalysis.com

You can also download the SAMPLE REPORT on cold chain by Roots Analysis.

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