Research Insights

Since the mid-twentieth century, computing devices have continually been explored for applications beyond mere calculations, to emerge as machines that possess intelligence. These targeted efforts have contributed to the introduction of artificial intelligence, the next-generation simulator that employs programmed machines possessing the ability to comprehend data and execute the instructed tasks. The progress of artificial intelligence can be attributed to machine learning, a field of study imp more

The therapeutic approach involving the injection of healthy cells in the human body to replace the diseased / non-functioning cells, in order to regulate certain functions, is referred to as cell therapy. In the past few years, this therapeutic approach has emerged as one of the key areas of interest in the healthcare sector, given its ability to treat diseases which were previously considered untreatable. Consequently, driven by the benefits offered by cellular therapies and recent approvals gr more

Orthokeratology is defined as the use of custom designed (as per the patient’s needs) and fitted contact lenses that are used to improve vision. This is achieved by temporarily reshaping the patient’s cornea. Majority of these novel ortho-k lenses are worn at night, during the sleep cycle, to reshape the front surface of the eye. It is worth highlighting that the United States Food and Drug Administration (USFDA) has recently stated that ortho-k lenses are safe for use by patients be more

Genotoxicity refers to the property of hazardous (physical, chemical and biological) agents to cause damage to genetic information present within a cell. It is worth mentioning that this damage can lead to formation of mutations, activation of mistimed event and direct DNA damage. Further, researchers have been able to link the mutations caused by genetic toxicology to various disease indications, including several oncological and genetic disorders. In addition, it is believed that the changes i more

The process of drug development, beginning from the discovery of a molecule to its commercial launch, takes around 10-15 years and capital investments worth USD 4-10 billion. It is a well-known fact that only a small proportion of molecules, which are selected for further investigation during the initial stages of research, are actually translated into product candidates. Given the complexities involved in the drug discovery process, the overall research and development (R&D) expenditure in more

Viral clearance and viral testing refers to the detection and elimination of viral contaminants, using a wide array of methods, to ensure the product’s safety for human use. Over the past few years, viral clearance and viral testing has emerged as one of the key pre-requisites for biopharmaceutical regulatory approvals. It is worth mentioning that, till date, over 630 biologics have already been approved by the Food and Drug Administration (FDA), while more than 8,000 biopharmaceuticals ar more

Digital health is a broad concept that encompasses telemedicine, teleconsultation, remote monitoring, connected devices, digital health platforms and health applications. The outbreak of COVID-19 pandemic has propelled the usage of digital technologies in order to receive healthcare, remotely. The revolutionary developments in digital health have transformed medicine and biomedical science as well as promoted early disease diagnosis and treatment. In addition, several FemTech startups are focuse more

In the past few years, modular facilities or prefabricated buildings have emerged as a promising alternative to the conventionally built pharma / biotech manufacturing facilities. Modular construction involves building of structures using prefabricated modular units, off-site, under controlled factory setting, which are later assembled on site.  It is interesting to note that off-site construction can eliminate 60%-90% of the weather-related project concerns.  Further, modular faciliti more

According to the National Health Council, nearly 40% of the adult population in the US is diagnosed with at least one chronic condition, such as diabetes, asthma, and hypertension. The annual cost burden associated with chronic diseases in the US is around USD 3.8 trillion. A major share of expenses incurred by patients living with a chronic disorder is driven by the frequent need to medicate, which may require repeated visits to hospitals / out-patient clinics. This has prompted stakeholders to more

Digital therapeutics are clinically validated solutions that are delivered as applications, software and online programs, demonstrating the capability to facilitate positive outcomes when employed in the management of clinical conditions. These therapeutics are designed to engage patients in personalized treatment or disease prevention programs, through mediating behavioral or psychological modifications. The primary benefits of digital therapeutics include reduction of treatment related costs, more

Tissue injury and dysfunctioning commonly occurs in humans; however, not in all cases, the tissue regeneration capability of a human body is able to cope up with the damage caused. The conventional approach used to deal with this type of trauma involves transplantation of damaged tissues or organs; this is further associated with several limitations, including non-availability of compatible organ donor, risk of graft rejection (due to the body’s immunological reaction) and post-surgical in more

TIL Therapy Overview The global TIL therapy market is a growing market within the cell therapy market and is estimated to grow at a CAGR of 40% during the forecast period. Over the years, various studies have validated the successful use of tumor infiltrating lymphocytes (TILs) in treating patients diagnosed with refractory diseases. TILs are a heterogeneous population of mononuclear lymphocytes that comprise of T-cells, B-cells, NK cells and macrophages isolated from the tumor. These ly more

Monkeypox is a viral disease, which is usually transmitted to humans from animals. The disease is known to have symptoms similar to those observed in smallpox patients, although it is considered to be clinically less severe. Monkeypox has recently emerged as a prominent orthopox virus affecting public health. In May 2022, multiple cases of the disease were reported in several non-endemic countries, thereby making monkeypox a disease of global concern. Consequently, in July 2022, the World Health more

Blockchain technology in healthcare (drug discovery and clinical trials), driven by 50+ companies, is anticipated to reach USD 640 million by 2035, growing at 22% CAGR. Blockchain technology, also referred to as distributed ledger technology (DLT), serves an integral part of the pharmaceutical supply chain. It enhances the trackability and traceability of drugs and other pharmaceutical products, thereby reducing the prevalence of counterfeit drugs and medicine. The drug discovery process, whi more

The concept of 3D printing has been one of the biggest revolutions across the globe. Various industry stakeholders and academicians have undertaken several initiatives to further develop / improve this technology for a variety of applications. One such application area is 3D bioprinting that includes the printing of living cells and enables the development of highly complex tissues that mimic the structure and performance ability of desired organ, within the body. Although 3D bioprinting results more

Dental 3D Printing Market Overview The dental 3D printing market is estimated to be USD 2.9 billion in 2023 and is anticipated to grow at an annualized growth rate (CAGR) of 15.1% during the forecast period 2023-2035. 3D printing, also known as additive manufacturing, is a method of producing 3-dimensional objects layer-by-layer, using a computer aided design. Owing to its ability to print complex models using a wide range of materials, 3D printing has applications across various industries, more
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